For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TRFTGLVTTASRTASRTAARTARADRATSTQEAILKAAERLYAEHGVFAVSNRQVSEAAGQGNNAAVGYH FGTKTDLVRAIEHKHRGPIEYLREQMIGTVQGSTDLRDWVGALVRPLTDHLAALGNPTWYARFAAQVMTD PAYHNIIVRDALSSPSLVQVIEGMNNCLPDLPAEIRAERNIMARNLLMHSCAERERALAQGAPVPRSSWQ GAASGLIDAIVGLWLAPVTGEDR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4858 | - | - | 100% (234) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_2179 | - | 8e-07 | 26.81% (138) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_3765 | - | 1e-05 | 34.52% (84) | transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2416 | - | 1e-104 | 80.00% (230) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0835c | - | 2e-12 | 40.59% (101) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4764 | - | 3e-92 | 75.46% (216) | hypothetical protein MMAR_4764 |
| M. avium 104 | MAV_0887 | - | 4e-93 | 75.91% (220) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2278 | - | 4e-90 | 74.19% (217) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_0335 | - | 4e-91 | 75.00% (216) | hypothetical protein MUL_0335 |
| M. vanbaalenii PYR-1 | Mvan_4236 | - | 1e-103 | 80.00% (230) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2416|M.gilvum_PYR-GCK MQSGATTFLNGTTHLKQSLDLPGVTRFTDRVTTARTVRADRATGTQEAIL
Mvan_4236|M.vanbaalenii_PYR-1 -----MSFLN------QSLDLVGVTGFTEWVTTARTVRADRASSTQEAIL
MMAR_4764|M.marinum_M -----MT------------------------AVGRAVRGERASSTQEAIL
MUL_0335|M.ulcerans_Agy99 -----MT------------------------AVGRAVRGERASSTQEAIL
MAV_0887|M.avium_104 -----MT------------------------TIGRPVRTERASSTQEAIL
MSMEG_4858|M.smegmatis_MC2_155 -----MTRFTG---------LVTTASRTASRTAARTARADRATSTQEAIL
TH_2278|M.thermoresistible__bu --VVQFTEG---------------------VTAARTVRADRASSTQEAIL
MAB_0835c|M.abscessus_ATCC_199 -----MT------------------------DTSAETTILTEDSTDQRLL
: . . .*:: :*
Mflv_2416|M.gilvum_PYR-GCK KAAERLYAEHGVFAVSNRQVSEAAGQGNNAAVGYHFGTKADLVRAIEHKH
Mvan_4236|M.vanbaalenii_PYR-1 KAAERLYAEHGVFAVSNRQVSEAAGQGNNAAVGYHFGTKADLVRAIEHKH
MMAR_4764|M.marinum_M VAAERLFAEHGVFAVSNRQVSEAAGQGNNAAVGYHFGTKTDLVRAIEQKH
MUL_0335|M.ulcerans_Agy99 VAAERLFAEHGVFAVSNRQVSEAAGQGNNAAVGYHFGTKTDLVRAIEQKH
MAV_0887|M.avium_104 VAAERLYAEHGMFAVSNRQVSEAAGQGNNAAVGYHFGTKADLVRAIEHKH
MSMEG_4858|M.smegmatis_MC2_155 KAAERLYAEHGVFAVSNRQVSEAAGQGNNAAVGYHFGTKTDLVRAIEHKH
TH_2278|M.thermoresistible__bu KAAERLYAERGMFAVSNRQVSEAAGQGNNAAVGYHFGTKTDLVRAIEQKH
MAB_0835c|M.abscessus_ATCC_199 NAAERLFAERGVDAVSLRAIMAAAG-TNVASVHYHFGSKERLIEALLDRY
*****:**:*: *** * : *** * *:* ****:* *:.*: .::
Mflv_2416|M.gilvum_PYR-GCK RGPIEELREQRVA-------AIDSSGDMRDWVAALVCPLTDHLAALGNPT
Mvan_4236|M.vanbaalenii_PYR-1 RGPIEELREQRVA-------AIGASTDMRDWVAALVCPLTDHLAALGNPT
MMAR_4764|M.marinum_M RVPVERLREQMVA----AAAAKGVAATMRDWVACLVCPLTEHLAVLGNPT
MUL_0335|M.ulcerans_Agy99 RVPIERLREQMVA----AAAAKGAAATMRDWVACLVCPLTEHLAVLGNPT
MAV_0887|M.avium_104 RGPVEQLREQMVADLLESGAGGGRDAELRSWVACLVRPLTDHLEELGNPT
MSMEG_4858|M.smegmatis_MC2_155 RGPIEYLREQMIG------TVQG-STDLRDWVGALVRPLTDHLAALGNPT
TH_2278|M.thermoresistible__bu RVEIERLLEKMVA-------ETGDSTDLRDWVACLVCSLTEHLHQLGNPT
MAB_0835c|M.abscessus_ATCC_199 LDQIEKRRFALLD-------VAETARTLRAIAEAIVTPLS-EIAEEGSTA
:* : :* . .:* .*: .: *..:
Mflv_2416|M.gilvum_PYR-GCK WYARFAAQVMT-DPAYHNMIVKDALSSPSLVRVLDGINGCLPDLPVDVRV
Mvan_4236|M.vanbaalenii_PYR-1 WYARFAAQVMT-DPAYHNMIVKDALSSPSLVRVLDGINSCLPDLPVDVRV
MMAR_4764|M.marinum_M WYARFAAQAMT-DPAYHNIIVKDALSSPSLVQVIDGINSCLPDLPVDVRY
MUL_0335|M.ulcerans_Agy99 WYARFAAQAMT-DPAYHNIIVKDALSSPSLVQVIDGINSCLPDLPVDVRY
MAV_0887|M.avium_104 WYARFAAQAMT-DPAYYNIIVKGALSSPSLVQVVEGINRCLPDLPAEVHF
MSMEG_4858|M.smegmatis_MC2_155 WYARFAAQVMT-DPAYHNIIVRDALSSPSLVQVIEGMNNCLPDLPAEIRA
TH_2278|M.thermoresistible__bu WYARFAAQALA-DPAYQKIVVKDALASPALVRVVEGITRCLPDLPAAVVV
MAB_0835c|M.abscessus_ATCC_199 WLSTLGKLLISGHPALIPMSVSFQPQAARLQELILRLRPDATLPSIRFGV
* : :. :: .** : * :. * .:: : . . .
Mflv_2416|M.gilvum_PYR-GCK ERNIMGRNLLMHSCADRERLLAQGSPVPRGSWQSAATGLIDAIIGLWHAP
Mvan_4236|M.vanbaalenii_PYR-1 ERNIMGRNLLMHSCADRERLLAQGAPVARPSWQAAATGLIDAIIGLWHAP
MMAR_4764|M.marinum_M ERNLMARNLLMHTCADLERALAAGTSVPRPSWREAATGLIDAITGLWLAP
MUL_0335|M.ulcerans_Agy99 ERNLMARNLLMHTCADLERALAAGTSVPRPFWREAATGQIDAITGLWLAP
MAV_0887|M.avium_104 ERNIMARNLLMHTCADRERALAAGTSTSHRSWRAAASGLIDAIVGLWLAP
MSMEG_4858|M.smegmatis_MC2_155 ERNIMARNLLMHSCAERERALAQGAPVPRSSWQGAASGLIDAIVGLWLAP
TH_2278|M.thermoresistible__bu ERNIMARNLLMHTCADFERAFAEGDPVPRASWQAVGNGLIDAIVGLWRAP
MAB_0835c|M.abscessus_ATCC_199 THAVTLTCVVLGDIAHTNRLMSLSGTYLDD--GQMNAQLIDMVTAILAGP
: : ::: *. :* :: . . ** : .: .*
Mflv_2416|M.gilvum_PYR-GCK VTERP-
Mvan_4236|M.vanbaalenii_PYR-1 VTEPA-
MMAR_4764|M.marinum_M VTARE-
MUL_0335|M.ulcerans_Agy99 VTARE-
MAV_0887|M.avium_104 VTPYE-
MSMEG_4858|M.smegmatis_MC2_155 VTGEDR
TH_2278|M.thermoresistible__bu VTEPPQ
MAB_0835c|M.abscessus_ATCC_199 PDES--