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M. avium 104 MAV_2967 (-)

annotation: transcriptional regulator, TetR family protein
coordinates: 3003184 - 3003918
length: 244

VFTEAMTAERIARSDRSTGTREAILSAAEVLFAERGMYAVSNRQISEAAGQGNNAAACYHFGTRVDLLRA
IEGKHREPIEKLRAQMLAAVGDSTELRDWVGTLVRPLTDHLSALGTPSWYARFAAQAMADPSYRHVVTKD
ALSSPLLVRTLDGINRCLPELPRRVRAERMVMVRNLLMHTCAEHEGALAEHGPRSRSAWPVAAEGLIDAI
VGLWRAPVHVAAAAGPTGQTTAPATGQTDHRGAP
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_2967--100% (244)transcriptional regulator, TetR family protein
M. avium 104MAV_0887-6e-7462.56% (219) transcriptional regulator, TetR family protein
M. avium 104MAV_2626-3e-1630.45% (220) transcriptional regulator, TetR family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_2416-2e-8065.44% (217) TetR family transcriptional regulator
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0835c-5e-1138.05% (113) TetR family transcriptional regulator
M. marinum MMMAR_4764-8e-7363.68% (212) hypothetical protein MMAR_4764
M. smegmatis MC2 155MSMEG_4858-1e-8267.13% (216) transcriptional regulator, TetR family protein
M. thermoresistible (build 8)TH_2278-8e-8065.44% (217) transcriptional regulator, TetR family protein
M. ulcerans Agy99MUL_0335-4e-7263.68% (212) hypothetical protein MUL_0335
M. vanbaalenii PYR-1Mvan_4236-4e-8165.90% (217) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2416|M.gilvum_PYR-GCK          MQSGATTFLNGTTHLKQSLDLPGVTRFTDRVTTARTVRADRATGTQEAIL
Mvan_4236|M.vanbaalenii_PYR-1       -----MSFLN------QSLDLVGVTGFTEWVTTARTVRADRASSTQEAIL
MMAR_4764|M.marinum_M               -----------------------------MTAVGRAVRGERASSTQEAIL
MUL_0335|M.ulcerans_Agy99           -----------------------------MTAVGRAVRGERASSTQEAIL
MSMEG_4858|M.smegmatis_MC2_155      --------------MTRFTGLVTTASRTASRTAARTARADRATSTQEAIL
TH_2278|M.thermoresistible__bu      -----------------------VVQFTEGVTAARTVRADRASSTQEAIL
MAV_2967|M.avium_104                -------------------------MFTEAMTAERIARSDRSTGTREAIL
MAB_0835c|M.abscessus_ATCC_199      -----------------------------MTDTSAETTILTEDSTDQRLL
                                                                    .   .      .* : :*

Mflv_2416|M.gilvum_PYR-GCK          KAAERLYAEHGVFAVSNRQVSEAAGQGNNAAVGYHFGTKADLVRAIEHKH
Mvan_4236|M.vanbaalenii_PYR-1       KAAERLYAEHGVFAVSNRQVSEAAGQGNNAAVGYHFGTKADLVRAIEHKH
MMAR_4764|M.marinum_M               VAAERLFAEHGVFAVSNRQVSEAAGQGNNAAVGYHFGTKTDLVRAIEQKH
MUL_0335|M.ulcerans_Agy99           VAAERLFAEHGVFAVSNRQVSEAAGQGNNAAVGYHFGTKTDLVRAIEQKH
MSMEG_4858|M.smegmatis_MC2_155      KAAERLYAEHGVFAVSNRQVSEAAGQGNNAAVGYHFGTKTDLVRAIEHKH
TH_2278|M.thermoresistible__bu      KAAERLYAERGMFAVSNRQVSEAAGQGNNAAVGYHFGTKTDLVRAIEQKH
MAV_2967|M.avium_104                SAAEVLFAERGMYAVSNRQISEAAGQGNNAAACYHFGTRVDLLRAIEGKH
MAB_0835c|M.abscessus_ATCC_199      NAAERLFAERGVDAVSLRAIMAAAG-TNVASVHYHFGSKERLIEALLDRY
                                     *** *:**:*: *** * :  ***  * *:. ****::  *:.*:  ::

Mflv_2416|M.gilvum_PYR-GCK          RGPIEELREQRVAAIDSS---GDMRDWVAALVCPLTDHLAALGNPTWYAR
Mvan_4236|M.vanbaalenii_PYR-1       RGPIEELREQRVAAIGAS---TDMRDWVAALVCPLTDHLAALGNPTWYAR
MMAR_4764|M.marinum_M               RVPVERLREQMVAAAAAKGVAATMRDWVACLVCPLTEHLAVLGNPTWYAR
MUL_0335|M.ulcerans_Agy99           RVPIERLREQMVAAAAAKGAAATMRDWVACLVCPLTEHLAVLGNPTWYAR
MSMEG_4858|M.smegmatis_MC2_155      RGPIEYLREQMIGTVQGS---TDLRDWVGALVRPLTDHLAALGNPTWYAR
TH_2278|M.thermoresistible__bu      RVEIERLLEKMVAETGDS---TDLRDWVACLVCSLTEHLHQLGNPTWYAR
MAV_2967|M.avium_104                REPIEKLRAQMLAAVGDS---TELRDWVGTLVRPLTDHLSALGTPSWYAR
MAB_0835c|M.abscessus_ATCC_199      LDQIEKRRFALLDVAETA---RTLRAIAEAIVTPLS-EIAEEGSTAWLST
                                       :*      :           :*  .  :* .*: .:   *..:* : 

Mflv_2416|M.gilvum_PYR-GCK          FAAQVMT-DPAYHNMIVKDALSSPSLVRVLDGINGCLPDLPVDVRVERNI
Mvan_4236|M.vanbaalenii_PYR-1       FAAQVMT-DPAYHNMIVKDALSSPSLVRVLDGINSCLPDLPVDVRVERNI
MMAR_4764|M.marinum_M               FAAQAMT-DPAYHNIIVKDALSSPSLVQVIDGINSCLPDLPVDVRYERNL
MUL_0335|M.ulcerans_Agy99           FAAQAMT-DPAYHNIIVKDALSSPSLVQVIDGINSCLPDLPVDVRYERNL
MSMEG_4858|M.smegmatis_MC2_155      FAAQVMT-DPAYHNIIVRDALSSPSLVQVIEGMNNCLPDLPAEIRAERNI
TH_2278|M.thermoresistible__bu      FAAQALA-DPAYQKIVVKDALASPALVRVVEGITRCLPDLPAAVVVERNI
MAV_2967|M.avium_104                FAAQAMA-DPSYRHVVTKDALSSPLLVRTLDGINRCLPELPRRVRAERMV
MAB_0835c|M.abscessus_ATCC_199      LGKLLISGHPALIPMSVSFQPQAARLQELILRLRPDATLPSIRFGVTHAV
                                    :.   :: .*:   : .     :. * . :  :    .  .  .   : :

Mflv_2416|M.gilvum_PYR-GCK          MGRNLLMHSCADRERLLAQGSPVPRGSWQSAATGLIDAIIGLWHAPVTER
Mvan_4236|M.vanbaalenii_PYR-1       MGRNLLMHSCADRERLLAQGAPVARPSWQAAATGLIDAIIGLWHAPVTEP
MMAR_4764|M.marinum_M               MARNLLMHTCADLERALAAGTSVPRPSWREAATGLIDAITGLWLAPVTAR
MUL_0335|M.ulcerans_Agy99           MARNLLMHTCADLERALAAGTSVPRPFWREAATGQIDAITGLWLAPVTAR
MSMEG_4858|M.smegmatis_MC2_155      MARNLLMHSCAERERALAQGAPVPRSSWQGAASGLIDAIVGLWLAPVTGE
TH_2278|M.thermoresistible__bu      MARNLLMHTCADFERAFAEGDPVPRASWQAVGNGLIDAIVGLWRAPVTEP
MAV_2967|M.avium_104                MVRNLLMHTCAEHEGALAEHGPRSRSAWPVAAEGLIDAIVGLWRAPVHVA
MAB_0835c|M.abscessus_ATCC_199      TLTCVVLGDIAHTNRLMSLSGTYLDD--GQMNAQLIDMVTAILAGPPDES
                                        :::   *. :  ::   .             ** : .:  .*    

Mflv_2416|M.gilvum_PYR-GCK          P----------------------
Mvan_4236|M.vanbaalenii_PYR-1       A----------------------
MMAR_4764|M.marinum_M               E----------------------
MUL_0335|M.ulcerans_Agy99           E----------------------
MSMEG_4858|M.smegmatis_MC2_155      DR---------------------
TH_2278|M.thermoresistible__bu      PQ---------------------
MAV_2967|M.avium_104                AAAGPTGQTTAPATGQTDHRGAP
MAB_0835c|M.abscessus_ATCC_199      -----------------------