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VNPRSILVLVQRFFSEGPSRKVLRRRLVALSVLPALLLLGFAVKLIVMVSTGYAAQSHYLAYDSYSLRDD VRILKSWNIIDSYKAYFTEGDRYVLEGRLAEAETEFKESLKRVDPPESCPVRINLEVVLETRGDLKSADH KRDDAKKFWEEALAVTREAPAGCFNTTSEPDEAVRKHLNETEQRLLDKLKDPPATSASPSPTTSPSPPPP EGGGGNGGDGQGGGNGGDGQGGGNDHNDGQRGGDQNGQPNSLPGEPTQEGPSPGQPTQAPTPVGPDRIPT SGANGANELHPDQGDPADVLKRSLENSTASGTDTE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0658 | - | - | 100% (315) | hypothetical protein MAB_0658 |
| M. abscessus ATCC 19977 | MAB_1830 | - | 8e-07 | 29.84% (124) | hypothetical protein MAB_1830 |
| M. abscessus ATCC 19977 | MAB_2532 | - | 7e-06 | 35.90% (78) | hypothetical protein MAB_2532 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1476c | PE_PGRS26 | 1e-08 | 44.05% (84) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_0044 | - | 5e-32 | 41.33% (196) | hypothetical protein Mflv_0044 |
| M. tuberculosis H37Rv | Rv1441c | PE_PGRS26 | 1e-08 | 44.05% (84) | PE-PGRS family protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_4475 | - | 2e-07 | 30.83% (120) | PE-PGRS family protein |
| M. avium 104 | MAV_0680 | - | 2e-08 | 37.84% (111) | hypothetical protein MAV_0680 |
| M. smegmatis MC2 155 | MSMEG_6606 | - | 2e-26 | 34.11% (214) | hypothetical protein MSMEG_6606 |
| M. thermoresistible (build 8) | TH_3947 | - | 5e-46 | 34.05% (373) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_1721 | - | 1e-06 | 36.84% (76) | PE_PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_0874 | - | 2e-30 | 36.36% (198) | hypothetical protein Mvan_0874 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0044|M.gilvum_PYR-GCK ---------------------MTRPPARIRLRRRLLLFSAVPAVLVTLLA
Mvan_0874|M.vanbaalenii_PYR-1 ---------------------MTRLPARIRLRRRLLLASAPPALVTVVVA
MSMEG_6606|M.smegmatis_MC2_155 ------------------------------MRRRLLVYSAPVAVVTVLII
TH_3947|M.thermoresistible__bu MMLMKRPAAAVRGVLNRMRATYRHGPSRLRLRWRLYAVSAPLIVVLLAVA
MAB_0658|M.abscessus_ATCC_1997 --------MNPRSILVLVQRFFSEGPSRKVLRRRLVALSVLPALLLLGFA
Mb1476c|M.bovis_AF2122/97 ----------MSNVMVVPGMLSAAAADVASIGAALSAANGAAAPTTAGVL
Rv1441c|M.tuberculosis_H37Rv ----------MSNVMVVPGMLSAAAADVASIGAALSAANGAAAPTTAGVL
MMAR_4475|M.marinum_M ----------MSFVLVTPEALSAAAADTARIGSAINAATTAAAAQTTSVV
MUL_1721|M.ulcerans_Agy99 ---------MSSFVIATPEFLTAAANDLSGIGDAVRAATGAAAPSTTAIA
MAV_0680|M.avium_104 --------------------MVGAAAVAAGLGISAASLNAGSAYSAPLDP
: .
Mflv_0044|M.gilvum_PYR-GCK VKLISVVVVGGAAQQHYATGDIGALSDDVS-----LLQFANMIEPANAAV
Mvan_0874|M.vanbaalenii_PYR-1 VKLISVVVVGNSAREHFASGDIGALSDDVS-----LLRILDVVEPANTAS
MSMEG_6606|M.smegmatis_MC2_155 VKLLSVVVAGRSVTSDYAERDAGAMAGGVS-----VLRVFNVVEPAKAHI
TH_3947|M.thermoresistible__bu AKMISVVLVGNSAIADFDRHDIESLRGDVA-----MLEFVNVIDPAKTSF
MAB_0658|M.abscessus_ATCC_1997 VKLIVMVSTGYAAQSHYLAYDSYSLRDDVR-----ILKSWNIIDSYKAYF
Mb1476c|M.bovis_AF2122/97 AAGADEVSAAIASLFSGYARDYQALSAQMARFHQQFVQALTASVGSYAAA
Rv1441c|M.tuberculosis_H37Rv AAGADEVSAAIASLFSGYARDYQALSAQMARFHQQFVQALTASVGSYAAA
MMAR_4475|M.marinum_M AAAGDEVSAAVATLFGTYGQTYQALAAQASTLHQQFENALTAAGSSYAGA
MUL_1721|M.ulcerans_Agy99 PLAGDEVSAAVTRMFGAYAQEFQTLSARMEQFYTDCVRALLTGAGAYSGA
MAV_0680|M.avium_104 PPPCPNCHGGGGNPGGPGGGPGGQPAGPGGGAGGQHGGNTPPQGGQNNPP
.
Mflv_0044|M.gilvum_PYR-GCK AAGGLAVLHD--------------RLDVADMQFTAALETTDDSRSCPVR-
Mvan_0874|M.vanbaalenii_PYR-1 AAGGLAVLQD--------------RLEEADAQFADALTRTGADRSCPVR-
MSMEG_6606|M.smegmatis_MC2_155 AEGARAVLED--------------RLTDAEQQYAQALGIAD---TCPVR-
TH_3947|M.thermoresistible__bu ANADLLVLEG--------------RLDDAEAKFRESLTRTDHGASCPAR-
MAB_0658|M.abscessus_ATCC_1997 TEGDRYVLEG--------------RLAEAETEFKESLKRVDPPESCPVR-
Mb1476c|M.bovis_AF2122/97 EAANASPLQA-------LEQQVLAAINAPTQTLLGRPLIGNGADGLPGQ-
Rv1441c|M.tuberculosis_H37Rv EAANASPLQA-------LEQQVLAAINAPTQTLLGRPLIGNGADGLPGQ-
MMAR_4475|M.marinum_M EAANAAPLQQTQAAFSTVERDVLSAVNAPSLALTGRPLIGNGADGGPGQ-
MUL_1721|M.ulcerans_Agy99 EAANASPLQT-------LEQDLLAGINAPSQMLTGRPLIGNGANGVDGTG
MAV_0680|M.avium_104 QNGPNNAPQN--------------GPNNAPQSGPNNPSQGGPNNAPQNG-
. . . .
Mflv_0044|M.gilvum_PYR-GCK ---INLELVRERRGDIDAWEARLDDARQRYEAALTVIADAPPACFAGNDD
Mvan_0874|M.vanbaalenii_PYR-1 ---VNLALVREREGDIDAWEARLEPARQRYESALAVIAEAPQGCFDGNTD
MSMEG_6606|M.smegmatis_MC2_155 ---VDLALVRETLGDRAASRFATPAAIAHYEAARDVVARAPQGCFTGNDD
TH_3947|M.thermoresistible__bu ---VNLELVQETLGDIATRSGRKDDAERWYRSAIGVVNDAPPACFADNDD
MAB_0658|M.abscessus_ATCC_1997 ---INLEVVLETRGDLKSADHKRDDAKKFWEEALAVTREAPAGCFNTTSE
Mb1476c|M.bovis_AF2122/97 -NGGAGGLLWGNGGNGGAGDAAHPNGGNGGDAGMFGNGGAGGAGYSPAAG
Rv1441c|M.tuberculosis_H37Rv -NGGAGGLLWGNGGNGGAGDAAHPNGGNGGDAGMFGNGGAGGAGYSPAAG
MMAR_4475|M.marinum_M -AGGAGGWLYGNGGNGGNGGAGQAGGG-GGSAGLLGNGGNGGNGGPGIP-
MUL_1721|M.ulcerans_Agy99 AAGGDGGWLVGNGGNGGSGAPGQAGGA-GGSAGLWGAGGAGGAGGSATTP
MAV_0680|M.avium_104 PNNPPQGGQNEPGGQYPPNQHGQNPPQNGQNQPPYDHDQNPPTPGGPTNA
*:
Mflv_0044|M.gilvum_PYR-GCK PDPQRRAVRADAAARVQAK----------------IDALGTVAPLAPPSP
Mvan_0874|M.vanbaalenii_PYR-1 PDSARRAVREDADERITAK----------------IDALGSVAPLAPP-P
MSMEG_6606|M.smegmatis_MC2_155 PDPQRRDIREQAQARLDDK----------------LTAMRTAAPPPPPPP
TH_3947|M.thermoresistible__bu PNEDRRAIRHEALPRLEQK----------------LANLRRPPEPPPPPP
MAB_0658|M.abscessus_ATCC_1997 PDEAVRKHLNETEQRLLDK----------------LKDPPATSASPSPTT
Mb1476c|M.bovis_AF2122/97 TGAAGGAGGAGGAGGWLSG-NGGAGGNGG------TGASGADGGGGLPPV
Rv1441c|M.tuberculosis_H37Rv TGAAGGAGGAGGAGGWLSG-NGGAGGNGG------TGASGADGGGGLPPV
MMAR_4475|M.marinum_M -GGPGPAGGNGGNGGLLFG-NGGAGGNGGDAYVFGNGQPGGSGGAGGDAH
MUL_1721|M.ulcerans_Agy99 -GGAGGAGGTGGANGLIGGGNGGVGGAGG------AGAAGGAGAVGSTAQ
MAV_0680|M.avium_104 PANTQNPPPPPERQRYAALN---------------PPNTQPPHPPYVPRH
Mflv_0044|M.gilvum_PYR-GCK PPPAAPVAP-----------------------------------------
Mvan_0874|M.vanbaalenii_PYR-1 PPVEAPAAP-----------------------------------------
MSMEG_6606|M.smegmatis_MC2_155 PPAAAPVPP-----------------------------------------
TH_3947|M.thermoresistible__bu NPIDPPPPPTSLTQMTSAPPLPHLGPAPDGAGAGDGAERAPQPGEGADQA
MAB_0658|M.abscessus_ATCC_1997 SPSPPPPEGGG---------------------------------------
Mb1476c|M.bovis_AF2122/97 PASPGGNGGGGGAG--GAAGMFGTG--GAGGTGGDGGAGGAGDSPNSGAN
Rv1441c|M.tuberculosis_H37Rv PASPGGNGGGGDAG--GAAGMFGTG--GAGGTGGDGGAGGAGDSPNSGAN
MMAR_4475|M.marinum_M LLGTGGAGGHGGLGSVGAAGTNPSGPYLQAASGTDGLSGSVGQPGGAGAD
MUL_1721|M.ulcerans_Agy99 AGGTGGDGGAGGAN-RQLVSLFGAG----GAGGADGAGGLGGNGGDATGF
MAV_0680|M.avium_104 DVVTASAQIGG---------------------------------------
Mflv_0044|M.gilvum_PYR-GCK ------------------------------------------TAPPPAGA
Mvan_0874|M.vanbaalenii_PYR-1 ------------------------------------------SAPPVAVP
MSMEG_6606|M.smegmatis_MC2_155 ------------------------------------------PAG--AGG
TH_3947|M.thermoresistible__bu PQPREGSDQAPQPGEGADEAPRPGDGSAEAPRPGDGEGPQPRAQPPLPGP
MAB_0658|M.abscessus_ATCC_1997 ---GNGGDGQGGGNGGDGQGGGNDHNDGQRGGDQNGQPNSLPGEPTQEGP
Mb1476c|M.bovis_AF2122/97 GARGGDGGNGAAGGAGGRLFGNGGAGGNGGTAGQGGDGGTALGAGGIGGD
Rv1441c|M.tuberculosis_H37Rv GARGGDGGNGAAGGAGGRLFGNGGAGGNGGTAGQGGDGGTALGAGGIGGD
MMAR_4475|M.marinum_M GNPGQQGGTGGTGGTSGVAAGSGGTGGTGGVGAPGGTG----GTGGISIS
MUL_1721|M.ulcerans_Agy99 GMTGGDGAMGGAVTVPVNFLAHAGSDGGIGTG----------GNGGLGGN
MAV_0680|M.avium_104 --PAGADVQFSIVGRGAPPPPREHGYGWNDGPPPHHPPPNWYGPPPPGGW
Mflv_0044|M.gilvum_PYR-GCK DQPRP-DERR------------------------------------LDIG
Mvan_0874|M.vanbaalenii_PYR-1 DTSDPSEARR------------------------------------LDRG
MSMEG_6606|M.smegmatis_MC2_155 TPPDTDTGDR------------------------------------LNPG
TH_3947|M.thermoresistible__bu NMPAPPTARGGEGPVVGPEGGDIDVLNPVSPDRLPSVGGGGPPGQELGIG
MAB_0658|M.abscessus_ATCC_1997 SPGQPTQAPTPVGPDRIPTSG-------------------ANGANELHPD
Mb1476c|M.bovis_AF2122/97 GGTGGAGGTG-GTAGIGGSSAGAG-------------------GAGGDGG
Rv1441c|M.tuberculosis_H37Rv GGTGGAGGTG-GTAGIGGSSAGAG-------------------GAGGDGG
MMAR_4475|M.marinum_M PNQAGGGGTG-GTGGIG-APGGTG-------------------GHGGDGG
MUL_1721|M.ulcerans_Agy99 GGAGGHGGINTGTRGTASASGGTG-------------------GNGGAGG
MAV_0680|M.avium_104 DGPPPPGGWNRPWDGPPRDVAVAR--------------------ADFGPF
Mflv_0044|M.gilvum_PYR-GCK -EDPLAALRQLLRDAAG---------------------------------
Mvan_0874|M.vanbaalenii_PYR-1 -GDPREALRQLLRDAAAG--------------------------------
MSMEG_6606|M.smegmatis_MC2_155 TGDPLERLQQILRDAAA---------------------------------
TH_3947|M.thermoresistible__bu DGDPLEQLRKLLDNANAHGDNRE---------------------------
MAB_0658|M.abscessus_ATCC_1997 QGDPADVLKRSLENSTASGTDTE---------------------------
Mb1476c|M.bovis_AF2122/97 AGGNGGGSSMIGGKGGTGGNGGVGGTGGASALTIGNGSSAGAGGAGGAG-
Rv1441c|M.tuberculosis_H37Rv AGGTGGGSSMIGGKGGTGGNGGVGGTGGASALTIGNGSSAGAGGAGGAG-
MMAR_4475|M.marinum_M AGGRGGLLFGVGGAGGAGGDGLDGGPG-AMGLTGGTGGHGGDNTSSATRP
MUL_1721|M.ulcerans_Agy99 NGGAPGAANAIGGQGGQGGIGGNGGNG-------GNGGTASSSNTGPTP-
MAV_0680|M.avium_104 SYNTFTVIPVFNWQYGGWGYWFFGVWVPLY--------------------
.
Mflv_0044|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0874|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6606|M.smegmatis_MC2_155 --------------------------------------------------
TH_3947|M.thermoresistible__bu --------------------------------------------------
MAB_0658|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1476c|M.bovis_AF2122/97 GTGGTGGYIESLDGKGQAGNGGNGGNGAAGGAGG-----GGTGAGGNGGA
Rv1441c|M.tuberculosis_H37Rv GTGGTGGYIESLDGKGQAGNGGNGGNGAAGGAGG-----GGTGAGGNGGA
MMAR_4475|M.marinum_M GVGGAGGYGGTGGTGGTGGTGGNGGNGGAGGAGGLFGQSGAAGAGGTAGA
MUL_1721|M.ulcerans_Agy99 -SAGTGG----------GGTGGGGGGGGGGGGGG------ASASGAVGGT
MAV_0680|M.avium_104 --------------------------------------------------
Mflv_0044|M.gilvum_PYR-GCK -------------------------------------------------
Mvan_0874|M.vanbaalenii_PYR-1 -------------------------------------------------
MSMEG_6606|M.smegmatis_MC2_155 -------------------------------------------------
TH_3947|M.thermoresistible__bu -------------------------------------------------
MAB_0658|M.abscessus_ATCC_1997 -------------------------------------------------
Mb1476c|M.bovis_AF2122/97 GGNGGDGGPS--QGGGNPGFGGDGGTGGPGGVGVPDGIGGANGAQGKHG
Rv1441c|M.tuberculosis_H37Rv GGNGGDGGPS--QGGGNPGFGGDGGTGGPGGVGVPDGIGGANGAQGKHG
MMAR_4475|M.marinum_M GGAGGTGGTGGVGGTGGTGAGGGGRTGGVGGDGVTGATG-ASGQPGASG
MUL_1721|M.ulcerans_Agy99 GGGGGGGGAGAAAGTGAVG-GGGGGAAPPAAPVAPPEMEAREATP----
MAV_0680|M.avium_104 -------------------------------------------------