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RRRLLVYSAPVAVVTVLIIVKLLSVVVAGRSVTSDYAERDAGAMAGGVSVLRVFNVVEPAKAHIAEGARA VLEDRLTDAEQQYAQALGIADTCPVRVDLALVRETLGDRAASRFATPAAIAHYEAARDVVARAPQGCFTG NDDPDPQRRDIREQAQARLDDKLTAMRTAAPPPPPPPPPAAAPVPPPAGAGGTPPDTDTGDRLNPGTGDP LERLQQILRDAAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6606 | - | - | 100% (224) | hypothetical protein MSMEG_6606 |
| M. smegmatis MC2 155 | MSMEG_5268 | - | 3e-05 | 51.28% (39) | hypothetical protein MSMEG_5268 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3906 | - | 9e-06 | 52.94% (34) | hypothetical protein Mb3906 |
| M. gilvum PYR-GCK | Mflv_0044 | - | 2e-51 | 50.43% (230) | hypothetical protein Mflv_0044 |
| M. tuberculosis H37Rv | Rv3876 | - | 9e-06 | 52.94% (34) | hypothetical protein Rv3876 |
| M. leprae Br4923 | MLBr_02395 | Ag36 | 1e-05 | 42.00% (50) | proline rich antigenic protein |
| M. abscessus ATCC 19977 | MAB_0658 | - | 8e-27 | 34.11% (214) | hypothetical protein MAB_0658 |
| M. marinum M | MMAR_3242 | mmpS3 | 2e-05 | 50.00% (38) | membrane protein MmpS3 |
| M. avium 104 | MAV_0158 | - | 1e-05 | 44.83% (58) | subtilase family protein |
| M. thermoresistible (build 8) | TH_3947 | - | 1e-37 | 40.81% (223) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3555 | mmpS3 | 2e-05 | 50.00% (38) | membrane protein MmpS3 |
| M. vanbaalenii PYR-1 | Mvan_0874 | - | 2e-51 | 50.66% (229) | hypothetical protein Mvan_0874 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3242|M.marinum_M --------------------MSGPNPPGWEPDEPDPAGDSSAELEPFGDT
MUL_3555|M.ulcerans_Agy99 --------------------MSGPNPPGWEPDEPDPAGDSSAELEPFGDT
Mb3906|M.bovis_AF2122/97 --------------------MAADYDKLFRPHEGMEAPDDMAAQPFFDPS
Rv3876|M.tuberculosis_H37Rv --------------------MAADYDKLFRPHEGMEAPDDMAAQPFFDPS
Mflv_0044|M.gilvum_PYR-GCK ---------------------MTRPPARIRLRRRLLLFSAVPAVLVTLLA
Mvan_0874|M.vanbaalenii_PYR-1 ---------------------MTRLPARIRLRRRLLLASAPPALVTVVVA
MSMEG_6606|M.smegmatis_MC2_155 ------------------------------MRRRLLVYSAPVAVVTVLII
TH_3947|M.thermoresistible__bu MMLMKRPAAAVRGVLNRMRATYRHGPSRLRLRWRLYAVSAPLIVVLLAVA
MAB_0658|M.abscessus_ATCC_1997 --------MNPRSILVLVQRFFSEGPSRKVLRRRLVALSVLPALLLLGFA
MAV_0158|M.avium_104 ------------------------------MDSPLRRAAALAGMTLVALS
MLBr_02395|M.leprae_Br4923 ----------------------------MTDQPPPSGSNPTPAPPPPGSS
MMAR_3242|M.marinum_M DDEPDDALAG------GELEPVSESGQIEPVDPAQESEAYSRAYSAPESE
MUL_3555|M.ulcerans_Agy99 GDEPDDALAG------GELEPVSESGQIEPVDPAQESEAYSRAYSAPESE
Mb3906|M.bovis_AF2122/97 ASFPPAPASANLPKPNGQTPPPTSDDLSERFVSAPPPPPPPPPPPPPTPM
Rv3876|M.tuberculosis_H37Rv ASFPPAPASANLPKPNGQTPPPTSDDLSERFVSAPPPPPPPPPPPPPTPM
Mflv_0044|M.gilvum_PYR-GCK VKLISVVVVG------GAAQQHYATGDIGALSDDVSLLQFANMIEPANAA
Mvan_0874|M.vanbaalenii_PYR-1 VKLISVVVVG------NSAREHFASGDIGALSDDVSLLRILDVVEPANTA
MSMEG_6606|M.smegmatis_MC2_155 VKLLSVVVAG------RSVTSDYAERDAGAMAGGVSVLRVFNVVEPAKAH
TH_3947|M.thermoresistible__bu AKMISVVLVG------NSAIADFDRHDIESLRGDVAMLEFVNVIDPAKTS
MAB_0658|M.abscessus_ATCC_1997 VKLIVMVSTG------YAAQSHYLAYDSYSLRDDVRILKSWNIIDSYKAY
MAV_0158|M.avium_104 ANVPAAQAITPPSVDPGMVPPDGPPRPDQPMRRANSCSAPITVRNPDVAQ
MLBr_02395|M.leprae_Br4923 GGYEPSFAPS-------ELGSAYPPPTAPPVGGSYPPPPPPGGSYPPPPP
. . .
MMAR_3242|M.marinum_M QFISGAYLPADLSLYDYDGYDDSLDEED--------EPSTPRWPWVVGVA
MUL_3555|M.ulcerans_Agy99 QFISGAYLPADLSLYDYDGYDDSLDEED--------EPSTPRWPWVVGVA
Mb3906|M.bovis_AF2122/97 PIAAGEPPSPEPAASKPPTPPMPIAGPEP----APPKPPTPPMPIAGPEP
Rv3876|M.tuberculosis_H37Rv PIAAGEPPSPEPAASKPPTPPMPIAGPEP----APPKPPTPPMPIAGPEP
Mflv_0044|M.gilvum_PYR-GCK VAAGGLAVLHDRLDVADMQFTAALETTDD----SRSCPVRINLELVRERR
Mvan_0874|M.vanbaalenii_PYR-1 SAAGGLAVLQDRLEEADAQFADALTRTGA----DRSCPVRVNLALVRERE
MSMEG_6606|M.smegmatis_MC2_155 IAEGARAVLEDRLTDAEQQYAQALGIAD-------TCPVRVDLALVRETL
TH_3947|M.thermoresistible__bu FANADLLVLEGRLDDAEAKFRESLTRTDH----GASCPARVNLELVQETL
MAB_0658|M.abscessus_ATCC_1997 FTEGDRYVLEGRLAEAETEFKESLKRVDP----PESCPVRINLEVVLETR
MAV_0158|M.avium_104 LAPGFNLLNIAKAWQYSTGNGVPVAVIDTGVSPNPRLPVVPGGDYIMGED
MLBr_02395|M.leprae_Br4923 PGGSYPPPPPSTGAYAPPPPGPAIRSLPK----------EAYTFWVTRVL
. .:
MMAR_3242|M.marinum_M AIMAAIALVASVSLLVTRTDSTKLANPA----TTSSVPPVQDEITTTKPP
MUL_3555|M.ulcerans_Agy99 AIMAAIALVASVSLLVTRTDSTKLANPA----TTSSVPPVQDEITTTKPP
Mb3906|M.bovis_AF2122/97 APPKPPTPPMPIAGPAPTPTESQLAPPR----PPTPQTPTGAPQQPESPA
Rv3876|M.tuberculosis_H37Rv APPKPPTPPMPIAGPAPTPTESQLAPPR----PPTPQTPTGAPQQPESPA
Mflv_0044|M.gilvum_PYR-GCK GDIDAWEARL-------DDARQRYEAAL----TVIADAPPACFAGNDDPD
Mvan_0874|M.vanbaalenii_PYR-1 GDIDAWEARL-------EPARQRYESAL----AVIAEAPQGCFDGNTDPD
MSMEG_6606|M.smegmatis_MC2_155 GDRAASRFAT-------PAAIAHYEAAR----DVVARAPQGCFTGNDDPD
TH_3947|M.thermoresistible__bu GDIATRSGRK-------DDAERWYRSAI----GVVNDAPPACFADNDDPN
MAB_0658|M.abscessus_ATCC_1997 GDLKSADHKR-------DDAKKFWEEAL----AVTREAPAGCFNTTSEPD
MAV_0158|M.avium_104 GLSDCDAHGTIVSSIIGAAPQGILPMPRPMPATPAFPPPAGPPPAVGAPP
MLBr_02395|M.leprae_Br4923 AYVIDN------------IPATVLLGIG----MLIQTLTKQEACVTDITQ
. . .
MMAR_3242|M.marinum_M PPPPPPPPPPSTEIPTATETQTVTVTPPPPPPPPPETSAAPPPAATT---
MUL_3555|M.ulcerans_Agy99 PPPPPPPPPPSTEIPTATETQTVTVTPPPPPPPPPETSAAPPPAATT---
Mb3906|M.bovis_AF2122/97 PHVPSHGPHQPRRTAPAPPWAKMPIGEPPPAPSRPSASPAEPPTRPAPQH
Rv3876|M.tuberculosis_H37Rv PHVPSHGPHQPRRTAPAPPWAKMPIGEPPPAPSRPSASPAEPPTRPAPQH
Mflv_0044|M.gilvum_PYR-GCK PQRRAVRADAAARVQAKIDALGTVAPLAPPSPPPPAAPVAP---------
Mvan_0874|M.vanbaalenii_PYR-1 SARRAVREDADERITAKIDALGSVAPLAPP-PPPVEAPAAP---------
MSMEG_6606|M.smegmatis_MC2_155 PQRRDIREQAQARLDDKLTAMRTAAPPPPPPPPPAAAPVPP---------
TH_3947|M.thermoresistible__bu EDRRAIRHEALPRLEQKLANLRRPPEPPPPPPNPIDPPPPPTSLTQMTSA
MAB_0658|M.abscessus_ATCC_1997 EAVRKHLNETEQRLLDKLKDPPATSASPSPTTSPSPPPPEGGG-------
MAV_0158|M.avium_104 PPVEVPPPVAPPPPPPPVTITQVLPPPPPPPPPPPEGGGATAASNGPP--
MLBr_02395|M.leprae_Br4923 YNVNQYCATQPTGIGMLAFWFAWLMATAYLVWNYGYRQGATG--------
.
MMAR_3242|M.marinum_M --------------------------------------------------
MUL_3555|M.ulcerans_Agy99 --------------------------------------------------
Mb3906|M.bovis_AF2122/97 SRRARRGHRYRTDTERNVGKVATGPSIQARLRAEEASGAQLAPGTEPSPA
Rv3876|M.tuberculosis_H37Rv SRRARRGHRYRTDTERNVGKVATGPSIQARLRAEEASGAQLAPGTEPSPA
Mflv_0044|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0874|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6606|M.smegmatis_MC2_155 --------------------------------------------------
TH_3947|M.thermoresistible__bu PPLPHLGPAPDGAGAGDGAERAPQPG---------------------EGA
MAB_0658|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0158|M.avium_104 --------------------------------------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
MMAR_3242|M.marinum_M -----------PTTPAAAPPPTTTTP------AGPRQVTYSVTGTKAPGD
MUL_3555|M.ulcerans_Agy99 -----------PTTPAAAPPPTTTTP------AGPRQVTYSVTGTKAPGD
Mb3906|M.bovis_AF2122/97 PLGQPRSYLAPPTRPAPTEPPPSPSPQRNSGRRAERRVHPDLAAQHAAAQ
Rv3876|M.tuberculosis_H37Rv PLGQPRSYLAPPTRPAPTEPPPSPSPQRNSGRRAERRVHPDLAAQHAAAQ
Mflv_0044|M.gilvum_PYR-GCK ---------------------------------------------TAPPP
Mvan_0874|M.vanbaalenii_PYR-1 ---------------------------------------------SAPPV
MSMEG_6606|M.smegmatis_MC2_155 ---------------------------------------------PAG--
TH_3947|M.thermoresistible__bu DQAPQPREGSDQAPQPGEGADEAPRPGDGSAEAPRPGDGEGPQPRAQPPL
MAB_0658|M.abscessus_ATCC_1997 ------GNGGDGQGGGNGGDGQGGGNDHNDGQRGGDQNGQPNSLPGEPTQ
MAV_0158|M.avium_104 ---------DPQTEDEPAVPPLPPGAPDGVVGVAPHATIISIRQSSRAFE
MLBr_02395|M.leprae_Br4923 ------------------------------------------SSIGKTVM
MMAR_3242|M.marinum_M IISVTYVDASGRRR------------------------------------
MUL_3555|M.ulcerans_Agy99 IISVTYVDASGRRR------------------------------------
Mb3906|M.bovis_AF2122/97 PDSITAATTGGRRRKRAAPDLDATQKSLRPAAKGPKVKKVKPQKPKATKP
Rv3876|M.tuberculosis_H37Rv PDSITAATTGGRRRKRAAPDLDATQKSLRPAAKGPKVKKVKPQKPKATKP
Mflv_0044|M.gilvum_PYR-GCK AGADQPRP-DERR-------------------------------------
Mvan_0874|M.vanbaalenii_PYR-1 AVPDTSDPSEARR-------------------------------------
MSMEG_6606|M.smegmatis_MC2_155 AGGTPPDTDTGDR-------------------------------------
TH_3947|M.thermoresistible__bu PGPNMPAPPTARGGEGPVVGPEGGDIDVL---------------------
MAB_0658|M.abscessus_ATCC_1997 EGPSPGQPTQAPTPVGPDRIPTSG--------------------------
MAV_0158|M.avium_104 PVNPPPGDPNSDEKVKAGTLNSVARAVVHAANMGAKVINISVTACLPAAA
MLBr_02395|M.leprae_Br4923 KFKVISEATGQPIG------------------------------------
MMAR_3242|M.marinum_M ---TQHNVYIPWSMTVTPISQ-----------------------------
MUL_3555|M.ulcerans_Agy99 ---TQHNVYIPWSMTVTPISQ-----------------------------
Mb3906|M.bovis_AF2122/97 PKVVSQRGWRHWVHALTRINLGLSPDEKYELDLHARVRRNPRGSYQIAVV
Rv3876|M.tuberculosis_H37Rv PKVVSQRGWRHWVHALTRINLGLSPDEKYELDLHARVRRNPRGSYQIAVV
Mflv_0044|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0874|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6606|M.smegmatis_MC2_155 --------------------------------------------------
TH_3947|M.thermoresistible__bu --------------------------------------------------
MAB_0658|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0158|M.avium_104 PADQRALGAALWYAATVKDAVVVAAAGNDG--------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
MMAR_3242|M.marinum_M --------------------------------------------------
MUL_3555|M.ulcerans_Agy99 --------------------------------------------------
Mb3906|M.bovis_AF2122/97 GLKGGAGKTTLTAALGSTLAQVRADRILALDADPGAGNLADRVGRQSGAT
Rv3876|M.tuberculosis_H37Rv GLKGGAGKTTLTAALGSTLAQVRADRILALDADPGAGNLADRVGRQSGAT
Mflv_0044|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0874|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6606|M.smegmatis_MC2_155 --------------------------------------------------
TH_3947|M.thermoresistible__bu -------------------------------NPVSPDRLPSVGGGGPPGQ
MAB_0658|M.abscessus_ATCC_1997 ---------------------------------------------ANGAN
MAV_0158|M.avium_104 ------------------------------EAGCNNNPMFDPLDPSDPRD
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
MMAR_3242|M.marinum_M -SDVGSVEASSLFRVSRLNCSITTSDGTVLSSNSNDAPQTSC--------
MUL_3555|M.ulcerans_Agy99 -SDVGSVEASSLFRVSRLNCSITTSDGTVLSSNSNDAPQTSC--------
Mb3906|M.bovis_AF2122/97 IADVLAEKELSHYNDIRAHTSVNAVNLEVLPAPEYSSAQRALSDADWHFI
Rv3876|M.tuberculosis_H37Rv IADVLAEKELSHYNDIRAHTSVNAVNLEVLPAPEYSSAQRALSDADWHFI
Mflv_0044|M.gilvum_PYR-GCK -LDIG-EDPLAALRQLLRDAAG----------------------------
Mvan_0874|M.vanbaalenii_PYR-1 -LDRG-GDPREALRQLLRDAAAG---------------------------
MSMEG_6606|M.smegmatis_MC2_155 -LNPGTGDPLERLQQILRDAAA----------------------------
TH_3947|M.thermoresistible__bu ELGIGDGDPLEQLRKLLDNANAHGDNRE----------------------
MAB_0658|M.abscessus_ATCC_1997 ELHPDQGDPADVLKRSLENSTASGTDTE----------------------
MAV_0158|M.avium_104 WHQVKVVSAPSWFSDYVLSVGAVDASGAALDKSMSGPWVGVAAPGTHIMG
MLBr_02395|M.leprae_Br4923 -FGMSVVRQLAHFVDAVICCIGFLFPLWDSKRQTLADKIMTTVCLPI---
MMAR_3242|M.marinum_M --------------------------------------------------
MUL_3555|M.ulcerans_Agy99 --------------------------------------------------
Mb3906|M.bovis_AF2122/97 ADPASRFYNLVLADCGAGFFDPLTRGVLSTVSGVVVVASVSIDGAQQASV
Rv3876|M.tuberculosis_H37Rv ADPASRFYNLVLADCGAGFFDPLTRGVLSTVSGVVVVASVSIDGAQQASV
Mflv_0044|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0874|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6606|M.smegmatis_MC2_155 --------------------------------------------------
TH_3947|M.thermoresistible__bu --------------------------------------------------
MAB_0658|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0158|M.avium_104 LSPQGGGPVNAYPPSRPGEKNMPFWGTSFSAAYVSGVAALVRAKFPELSA
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
MMAR_3242|M.marinum_M --------------------------------------------------
MUL_3555|M.ulcerans_Agy99 --------------------------------------------------
Mb3906|M.bovis_AF2122/97 ALDWLRNNGYQDLASRACVVINHIMPGEPNVAVKDLVRHFEQQVQPGRVV
Rv3876|M.tuberculosis_H37Rv ALDWLRNNGYQDLASRACVVINHIMPGEPNVAVKDLVRHFEQQVQPGRVV
Mflv_0044|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0874|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6606|M.smegmatis_MC2_155 --------------------------------------------------
TH_3947|M.thermoresistible__bu --------------------------------------------------
MAB_0658|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0158|M.avium_104 HQVINRIVQSAHNPPAGVDNKVGYGLVDPVAALTFNIPPGDRMAPGSQSR
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
MMAR_3242|M.marinum_M --------------------------------------------
MUL_3555|M.ulcerans_Agy99 --------------------------------------------
Mb3906|M.bovis_AF2122/97 VMPWDRHIAAGTEISLDLLDPIYKRKVLELAAALSDDFERAGRR
Rv3876|M.tuberculosis_H37Rv VMPWDRHIAAGTEISLDLLDPIYKRKVLELAAALSDDFERAGRR
Mflv_0044|M.gilvum_PYR-GCK --------------------------------------------
Mvan_0874|M.vanbaalenii_PYR-1 --------------------------------------------
MSMEG_6606|M.smegmatis_MC2_155 --------------------------------------------
TH_3947|M.thermoresistible__bu --------------------------------------------
MAB_0658|M.abscessus_ATCC_1997 --------------------------------------------
MAV_0158|M.avium_104 IITPAPPPPPPDHRARNIAIGFLGTVAAGVLVLAIAARLRRAR-
MLBr_02395|M.leprae_Br4923 --------------------------------------------