For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TRLPARIRLRRRLLLASAPPALVTVVVAVKLISVVVVGNSAREHFASGDIGALSDDVSLLRILDVVEPAN TASAAGGLAVLQDRLEEADAQFADALTRTGADRSCPVRVNLALVREREGDIDAWEARLEPARQRYESALA VIAEAPQGCFDGNTDPDSARRAVREDADERITAKIDALGSVAPLAPPPPPVEAPAAPSAPPVAVPDTSDP SEARRLDRGGDPREALRQLLRDAAAG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0874 | - | - | 100% (237) | hypothetical protein Mvan_0874 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_0044 | - | 2e-84 | 69.49% (236) | hypothetical protein Mflv_0044 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0658 | - | 1e-30 | 36.36% (198) | hypothetical protein MAB_0658 |
| M. marinum M | MMAR_5240 | dnaZX | 8e-06 | 31.45% (159) | DNA polymerase III (subunit gamma/tau) DnaZX |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_6606 | - | 2e-51 | 50.66% (229) | hypothetical protein MSMEG_6606 |
| M. thermoresistible (build 8) | TH_4401 | - | 2e-49 | 46.22% (238) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4315 | dnaZX | 6e-06 | 31.45% (159) | DNA polymerase III subunits gamma and tau |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0874|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0044|M.gilvum_PYR-GCK --------------------------------------------------
TH_4401|M.thermoresistible__bu --------------------------------------------------
MSMEG_6606|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0658|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_5240|M.marinum_M MALYRKYRPATFAEVVGQEHVTEPLSIALEAGRINHAYLFSGPRGCGKTS
MUL_4315|M.ulcerans_Agy99 MALYRKYRPATFAEVVGQEHVTEPLSIALEAGRINHAYLFSGPRGCGKTS
Mvan_0874|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0044|M.gilvum_PYR-GCK --------------------------------------------------
TH_4401|M.thermoresistible__bu --------------------------------------------------
MSMEG_6606|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0658|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_5240|M.marinum_M SARILARSLNCAQGPTATPCGTCESCQALAPSAPGSIDVVELDAASHGGV
MUL_4315|M.ulcerans_Agy99 SARILARSLNCAQGPTATPCGTCESCQALAPSAPGSIDVVELDAASHGGV
Mvan_0874|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0044|M.gilvum_PYR-GCK --------------------------------------------------
TH_4401|M.thermoresistible__bu --------------------------------------------------
MSMEG_6606|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0658|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_5240|M.marinum_M DDTRELRDRAFYAPAQSRYRVFIIDEAHMVTTAGFNALLKIVEEPPEHLI
MUL_4315|M.ulcerans_Agy99 DDTRELRDRAFYAPAQSRYRVFIIDEAHMVTTAGFNALLKIVEEPPEHLI
Mvan_0874|M.vanbaalenii_PYR-1 ----------------------MTRLPARIRLRRRLLLASAPPALVTVVV
Mflv_0044|M.gilvum_PYR-GCK ----------------------MTRPPARIRLRRRLLLFSAVPAVLVTLL
TH_4401|M.thermoresistible__bu ---------------------VTGRLPARVRLRRRLLIYSAPVAVGVLLT
MSMEG_6606|M.smegmatis_MC2_155 -------------------------------MRRRLLVYSAPVAVVTVLI
MAB_0658|M.abscessus_ATCC_1997 ---------MNPRSILVLVQRFFSEGPSRKVLRRRLVALSVLPALLLLGF
MMAR_5240|M.marinum_M FIFATTEPEKVLPTIRSRTHHYPFRLLPPRTMRGLIGRICEQEGVVVDEA
MUL_4315|M.ulcerans_Agy99 FIFATTEPEKVLPTIRSRTHHYPFRLLPRRTMRGLIGRICEQEGVVVDEA
:* : . .:
Mvan_0874|M.vanbaalenii_PYR-1 AVKLISVVVVG--------------------------------------N
Mflv_0044|M.gilvum_PYR-GCK AVKLISVVVVG--------------------------------------G
TH_4401|M.thermoresistible__bu AIKLISVVIAG--------------------------------------H
MSMEG_6606|M.smegmatis_MC2_155 IVKLLSVVVAG--------------------------------------R
MAB_0658|M.abscessus_ATCC_1997 AVKLIVMVSTG--------------------------------------Y
MMAR_5240|M.marinum_M VYPLVTRAGGGSPRDTLSVLDQLVAGAQSNHVTYQRALGLLGATDVALID
MUL_4315|M.ulcerans_Agy99 VYPLVTRAGGGSPRDTLSVLDQLVAGAQSNHVTYQRVLGLLGATDVALID
*: . *
Mvan_0874|M.vanbaalenii_PYR-1 SAREHFASGDIGALSDDVS----------------------LLRILDVVE
Mflv_0044|M.gilvum_PYR-GCK AAQQHYATGDIGALSDDVS----------------------LLQFANMIE
TH_4401|M.thermoresistible__bu SAAAHFAAGDADGLRRDVA----------------------TLHLADVIE
MSMEG_6606|M.smegmatis_MC2_155 SVTSDYAERDAGAMAGGVS----------------------VLRVFNVVE
MAB_0658|M.abscessus_ATCC_1997 AAQSHYLAYDSYSLRDDVR----------------------ILKSWNIID
MMAR_5240|M.marinum_M DAVDALGAGDAAALFGAVESVIDAGHDPRRFATDLLERFRDLIVLQAVPD
MUL_4315|M.ulcerans_Agy99 DAVDALGAGDAAALFGAVESVIDAGHDPRRFATDLLERFRDLIVLQAVPD
. * .: * : : :
Mvan_0874|M.vanbaalenii_PYR-1 PANTASAAGGLAVLQDR-----------LEEADAQFADALTRTGADRSCP
Mflv_0044|M.gilvum_PYR-GCK PANAAVAAGGLAVLHDR-----------LDVADMQFTAALETTDDSRSCP
TH_4401|M.thermoresistible__bu PQKARFAAGTLAVLDGR-----------LADADARFTEVLSGTAAPHSCP
MSMEG_6606|M.smegmatis_MC2_155 PAKAHIAEGARAVLEDR-----------LTDAEQQYAQALG---IADTCP
MAB_0658|M.abscessus_ATCC_1997 SYKAYFTEGDRYVLEGR-----------LAEAETEFKESLKRVDPPESCP
MMAR_5240|M.marinum_M AVSRGVVDGPEDVLDRMREQAAHLGAATLTRYAEVVQAGLGEMRGATAPR
MUL_4315|M.ulcerans_Agy99 AVSHGVVDGPEDVLDRMREQAAHLGSATLTRYAEVVQAGLGEMRGATAPR
. . . * **. * * :
Mvan_0874|M.vanbaalenii_PYR-1 VRVNLALVREREGDIDAWEARLEPARQRYESALAVIAEAPQGCFDGNTDP
Mflv_0044|M.gilvum_PYR-GCK VRINLELVRERRGDIDAWEARLDDARQRYEAALTVIADAPPACFAGNDDP
TH_4401|M.thermoresistible__bu VRINLELVRERQGDHAAWAGRPDAARERYRSALRIVDEAPPACFAGNTDP
MSMEG_6606|M.smegmatis_MC2_155 VRVDLALVRETLGDRAASRFATPAAIAHYEAARDVVARAPQGCFTGNDDP
MAB_0658|M.abscessus_ATCC_1997 VRINLEVVLETRGDLKSADHKRDDAKKFWEEALAVTREAPAGCFNTTSEP
MMAR_5240|M.marinum_M LLLEVVCARLLLPSASDAESALLQRIERIETRLAMSIPAGAGATSAPAPE
MUL_4315|M.ulcerans_Agy99 LLLEVVCARLLLPSASDAESALLQRIERIETRLAMSIPAGAGATSAPAPE
: ::: . . . : * ..
Mvan_0874|M.vanbaalenii_PYR-1 DSAR-------RAVR-----EDADERITAKIDALG--SVAPLAPP-PPPV
Mflv_0044|M.gilvum_PYR-GCK DPQR-------RAVR-----ADAAARVQAKIDALG--TVAPLAPPSPPPP
TH_4401|M.thermoresistible__bu DPER-------RXXXXGPGLALGFRRWLAPPVGLGDGDRNPSAPQLVCEE
MSMEG_6606|M.smegmatis_MC2_155 DPQR-------RDIR-----EQAQARLDDKLTAMR--TAAPPPPPPPPPA
MAB_0658|M.abscessus_ATCC_1997 DEAV-------RKHLN-ETEQRLLDKLKDPPATSASPSPTTSPSPPPPEG
MMAR_5240|M.marinum_M APAAPEAPAAPRATTSARAEAKEMVRQSMRRPAPPEPKSAPERPPAPEPR
MUL_4315|M.ulcerans_Agy99 APAA------PRATTSARAGAKEMVRQSMRRPAPPEPKSVPEPPPAPEPR
* : . .
Mvan_0874|M.vanbaalenii_PYR-1 EAPAAP--------------------SAPPVAVPDTSDPS-EARRLDRGG
Mflv_0044|M.gilvum_PYR-GCK AAPVAP--------------------TAPPPAGADQPRP--DERRLDIGE
TH_4401|M.thermoresistible__bu TGQDCG--------------------TGHFGGRVDEHRCRSDGQRRHRGA
MSMEG_6606|M.smegmatis_MC2_155 AAPVPP--------------------PAGAGGTPPDTDT---GDRLNPGT
MAB_0658|M.abscessus_ATCC_1997 GGGNGG--------------------DGQGGGNGGDGQGGGNDHNDGQRG
MMAR_5240|M.marinum_M PAPEPRRAPEPRPAPESRPAPVPEPVSAPGELNAAAVRSMWPTVREKVRQ
MUL_4315|M.ulcerans_Agy99 PAPEPRRAPEPR------PAPVPEPVSAPGELNAAAVRSMWPTVREKVRQ
. . .
Mvan_0874|M.vanbaalenii_PYR-1 -DPRE-------------------------------------ALRQLLR-
Mflv_0044|M.gilvum_PYR-GCK -DPLA-------------------------------------ALRQLLR-
TH_4401|M.thermoresistible__bu -DDRADTVDIVGSGDELNR--------------------ARGAHRDMLRR
MSMEG_6606|M.smegmatis_MC2_155 GDPLER-------------------------------------LQQILR-
MAB_0658|M.abscessus_ATCC_1997 GDQNGQPNSLPGEPTQEGP--------------------SPGQPTQAPTP
MMAR_5240|M.marinum_M RSRTTEVMLAAATVRALEDNTLVLTHDSAPLARRLSEQRNADVIAEALRD
MUL_4315|M.ulcerans_Agy99 RSRTTEVMLAAATVRALEDNTLVLTHDSAPLARRLSEQRNADVIAEALRD
. :
Mvan_0874|M.vanbaalenii_PYR-1 --------------------------DAAAG-------------------
Mflv_0044|M.gilvum_PYR-GCK --------------------------DAAG--------------------
TH_4401|M.thermoresistible__bu DLHHRSRGAGPLGEKFGAAVHLHQLGDGARGVEHPLDPIP----------
MSMEG_6606|M.smegmatis_MC2_155 --------------------------DAAA--------------------
MAB_0658|M.abscessus_ATCC_1997 VGPDRIPTSGANG----ANELHPDQGDPADVLKRSLENSTASGTDTE---
MMAR_5240|M.marinum_M ALGVNWRVRCEVGAAEPAATPTPAKAAAPAADPVAVDSARREEEESLLAE
MUL_4315|M.ulcerans_Agy99 ALGVNWRVRCEVGAAEPAATPTPAKAAAPAADPVAVDSARREEEESLLAE
.
Mvan_0874|M.vanbaalenii_PYR-1 ---------------------------------
Mflv_0044|M.gilvum_PYR-GCK ---------------------------------
TH_4401|M.thermoresistible__bu ---------------------------------
MSMEG_6606|M.smegmatis_MC2_155 ---------------------------------
MAB_0658|M.abscessus_ATCC_1997 ---------------------------------
MMAR_5240|M.marinum_M AGRSDPSEPRRDPEEVALELLRNELGARRIDNA
MUL_4315|M.ulcerans_Agy99 AGRSDPSEPRRDPEEVALELLRNELGARRIDNA