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SSFVIATPEFLTAAANDLSGIGDAVRAATGAAAPSTTAIAPLAGDEVSAAVTRMFGAYAQEFQTLSARME QFYTDCVRALLTGAGAYSGAEAANASPLQTLEQDLLAGINAPSQMLTGRPLIGNGANGVDGTGAAGGDGG WLVGNGGNGGSGAPGQAGGAGGSAGLWGAGGAGGAGGSATTPGGAGGAGGTGGANGLIGGGNGGVGGAGG AGAAGGAGAVGSTAQAGGTGGDGGAGGANRQLVSLFGAGGAGGADGAGGLGGNGGDATGFGMTGGDGAMG GAVTVPVNFLAHAGSDGGIGTGGNGGLGGNGGAGGHGGINTGTRGTASASGGTGGNGGAGGNGGAPGAAN AIGGQGGQGGIGGNGGNGGNGGTASSSNTGPTPSAGTGGGGTGGGGGGGGGGGGGGASASGAVGGTGGGG GGGGAGAAAGTGAVGGGGGGAAPPAAPVAPPEMEAREATP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1721 | - | - | 100% (461) | PE_PGRS family protein |
| M. ulcerans Agy99 | MUL_0572 | - | e-114 | 45.42% (557) | PE-PGRS family protein |
| M. ulcerans Agy99 | MUL_0212 | - | e-113 | 49.29% (495) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0857c | PE_PGRS14 | 1e-117 | 48.07% (543) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 9e-81 | 53.17% (331) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv3345c | PE_PGRS50 | 1e-118 | 49.29% (493) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 2e-14 | 39.39% (99) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 2e-41 | 37.50% (336) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_2116 | - | 0.0 | 70.74% (605) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 1e-24 | 40.91% (198) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 3e-60 | 41.73% (405) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 8e-43 | 41.25% (303) | PUTATIVE - |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 5e-78 | 49.57% (347) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_1721|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2116|M.marinum_M --------------------------------------------------
Mb0857c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_1721|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2116|M.marinum_M --------------------------------------------------
Mb0857c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_1721|M.ulcerans_Agy99 -----------------------------------------MSSFVIATP
MMAR_2116|M.marinum_M -----------------------------------------MSSFVIATP
Mb0857c|M.bovis_AF2122/97 -----------------------------------------MS-FVIAAP
MLBr_01183|M.leprae_Br4923 -----------------------------------------MPLFLNAEP
Rv3345c|M.tuberculosis_H37Rv -----------------------------------------MVMSLMVAP
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP
MAV_4827|M.avium_104 -------------------------------------MNIVLGVSMAPSS
MUL_1721|M.ulcerans_Agy99 ----------------------------------------EFLTAAANDL
MMAR_2116|M.marinum_M ----------------------------------------EFLTAAANDL
Mb0857c|M.bovis_AF2122/97 ----------------------------------------DLVAMATEDL
MLBr_01183|M.leprae_Br4923 ----------------------------------------QALTAAANTL
Rv3345c|M.tuberculosis_H37Rv ----------------------------------------ELVAAAAADL
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu ------------------------------------------VDGDGGS-
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------VEAASYVADPEAAL
MAV_4827|M.avium_104 IQMVVLEG--------------------------------EYADGATVEE
MUL_1721|M.ulcerans_Agy99 SGIG-----------------DAVRAATGAAAPSTTAIAPLAGDEVSAAV
MMAR_2116|M.marinum_M SGIG-----------------DAVRAATGAAAPSTTAIAPLAGDEVSAAV
Mb0857c|M.bovis_AF2122/97 AGIG-----------------ASLTAANAAAAVPTSGLLAAAGDEVSAAI
MLBr_01183|M.leprae_Br4923 EGLS-----------------AATVASNAAAAQLTTEIAPPAADDVSILL
Rv3345c|M.tuberculosis_H37Rv TGIG-----------------QAISAANAAAAGPTTQVLAAAGDEVSAAI
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu ----------------------------------------GGRTGLFSKL
MAB_4284c|M.abscessus_ATCC_199 ANAG--------------------LSAVSAAQVGAVMPVVAESVASNYGY
MAV_4827|M.avium_104 DAID-------------------VTGADDAATASAPDRVISAILGTREGA
MUL_1721|M.ulcerans_Agy99 TRMFGAYAQEFQTLSARMEQFYTDCVRALLTGAGAYSGAEAANASPLQTL
MMAR_2116|M.marinum_M TRMFGAYAQEFQTLSARMEQFHTDFVRALLTGAGAYSGAEAANASPLQTL
Mb0857c|M.bovis_AF2122/97 AALFSSHGQQYQAMSAQAAAFHARFVQALAGAMGAYAAAEAANASPLQTL
MLBr_01183|M.leprae_Br4923 AHFFSGHGRQYQAHASQGATNHQDLIQSLLTSSSAYAGTETANHDSL---
Rv3345c|M.tuberculosis_H37Rv AALFGTHAQEYQALSARVATFHEQFVRSLTAAGSAYATAEAANASPLQAL
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu SRGGDGGDGGLGGNGGHGGGTGIISLLSLAGNGGNGGNGYRTTDNNALDG
MAB_4284c|M.abscessus_ATCC_199 QSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDNDFLSHNDT
MAV_4827|M.avium_104 ADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAAALAQN
.
MUL_1721|M.ulcerans_Agy99 EQDLLAGINAPSQMLTGRPLIGNGANGVDGTGAAGGDGGWLVGNGGNGGS
MMAR_2116|M.marinum_M EQDLLAGINAPSQMLTGRPLIGNGANGVDGTGAAGGDGGWLVGNGGNGGS
Mb0857c|M.bovis_AF2122/97 EQGLLGAINAPAAALSGRPFIGNGTNGAPGTGEAGGPGGWLLGNGGNGGS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv EQQVLGAINAPTQLWLGRPLIGDGVHGAPGTGQPGGAGGLLWGNGGNGGS
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu GHGGNGGNVGFFSLFNLGGAGGWGGSGVDGVDVVGG-------NPDGGTP
MAB_4284c|M.abscessus_ATCC_199 DFASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTTAIGDG
MAV_4827|M.avium_104 VGGAMGYERTAVLLVEPDTATLAVVETSDGSIPDVYKQQIRAESYGDAAG
MUL_1721|M.ulcerans_Agy99 GAPGQAGGAGGSAGLWGAGGAGGAGGSATTPG------------------
MMAR_2116|M.marinum_M GAPGQAGGAGGSAGLWGAGGAGGAGGSATTPG------------------
Mb0857c|M.bovis_AF2122/97 GAPGQTGGAGGAAGLLGHGGTGGAGGTGASGGKGGTGGW-------LWGS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv GAAGQVGGPGGAAGLFGNGGSGGSGGAGAAGGVGGSGGW-------LNGN
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_3810|M.thermoresistible__bu GAHGESHTPGVYTDRQGEDGEDGTG-------------------------
MAB_4284c|M.abscessus_ATCC_199 AVAVGGSNSGPIASGQGSTAVNGDVRDSNIIN------------------
MAV_4827|M.avium_104 QLSAMVAGLEKLESLPGGLLLVGSGVDVAPLKQVLQT------------T
MUL_1721|M.ulcerans_Agy99 -GAGGAGGTGGANGLIGG--------------------------------
MMAR_2116|M.marinum_M -GAGGAGGTGGANGLIGG--------------------------------
Mb0857c|M.bovis_AF2122/97 GGAGGAGGSGGGSGGAGGNALMFGIGGNGGA-------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv GGAGGAGGTG-ANGGAGGNAWLFGAGGSGGAGTNGGVGGSGGFVYGNGGA
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----------------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----------------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGA-------------
TH_3810|M.thermoresistible__bu TGIGGRGGNGGSSSGTHP--------------------------------
MAB_4284c|M.abscessus_ATCC_199 ADHGSNVGVDQSQTRVGG--------------------------------
MAV_4827|M.avium_104 TFLDVSVAEEPETALARG--------------------------------
MUL_1721|M.ulcerans_Agy99 ----------------------------------------------GNGG
MMAR_2116|M.marinum_M ----------------------------------------------GNGG
Mb0857c|M.bovis_AF2122/97 ---------------------------------------GGAASGVGNGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv GGIGGIGGIGGNGGDAGLFGNGGAGGAGAAGLPGAAGLNGGDGSDGGNGG
Mflv_5091|M.gilvum_PYR-GCK -------------------------------AVGAAGAAG------TVGT
Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------AIGTAGVAG------AAGT
MSMEG_0868|M.smegmatis_MC2_155 ------------------ILIGANGGTVDGHAIGGNGGNGGNGSTTAAGG
TH_3810|M.thermoresistible__bu ---------------------------------------------MAEDG
MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------DYTNVSG
MAV_4827|M.avium_104 ---------------------------------------------AALAA
MUL_1721|M.ulcerans_Agy99 VGGAGGAG-----------------AAGGAGAVGSTAQAGG---------
MMAR_2116|M.marinum_M VGGAGGAG-----------------AAGGAGAVGSTAQAGG---------
Mb0857c|M.bovis_AF2122/97 VGGAGGAGG-------------ALVAIGGAGGAGGAATTG----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv TGGNGGRGG-------------LLVGNGGAGGAGGVGGDGGKGGAGDPSF
Mflv_5091|M.gilvum_PYR-GCK AGATGGTG---------------TGANGGAGGVGGVGGTGAAG-------
Mvan_1264|M.vanbaalenii_PYR-1 AGATGGTG---------------VGGNGGAGQAGGIGGTGAAG-------
MSMEG_0868|M.smegmatis_MC2_155 NGGTGGTGRVIAEGTGSTAEGTATGGDGGHSTGTGIGGNGGIGSVYAYGN
TH_3810|M.thermoresistible__bu EHVKALDGR--------------PGLDGGNGSHGGNGGHGG---------
MAB_4284c|M.abscessus_ATCC_199 HGSADIDKS--------------VTVVDDHSQRNTTNINDSFN-------
MAV_4827|M.avium_104 ANAPLFASS---------------TAALAYAQDPGTGAVDQYS-------
MUL_1721|M.ulcerans_Agy99 -----------------TGGDGGAG-------------------------
MMAR_2116|M.marinum_M -----------------AGGDGGAG-------------------------
Mb0857c|M.bovis_AF2122/97 -----------------TGGAGGAG-------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv AVNNGAGGNGGHGGNPGVGGAGGAGGLLAGAHGAAGATPTSGGNGGDGGI
Mflv_5091|M.gilvum_PYR-GCK -------AAGGAGGLGETGTTGGAGGVGGQ--------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------AAGQAGTAGETGVTGGVGGIGGQ--------------------
MSMEG_0868|M.smegmatis_MC2_155 NGAVSGTATGGRGGDGIDGGTGGAGGMGEIY-------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------TDRSTNIGSG-------------------------
MAV_4827|M.avium_104 -----------LPDYLYVPVDPEPG-------------------------
MUL_1721|M.ulcerans_Agy99 ----------------GANRQLVSLFGAGGAGGAD---------------
MMAR_2116|M.marinum_M ----------------GANRQLVSLFGAGGAGGAGGAG------------
Mb0857c|M.bovis_AF2122/97 ---------------SNALGLFLGLGGSGGQGGDSAMGSGGAG-------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv GATANSPLQAGGAGGNGGHGGLVGNGGTGGAGGAGHAGSTGATGTALQPT
Mflv_5091|M.gilvum_PYR-GCK ----------------GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQ
Mvan_1264|M.vanbaalenii_PYR-1 ----------------GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQ
MSMEG_0868|M.smegmatis_MC2_155 ---------------SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQ
TH_3810|M.thermoresistible__bu ------------------RGGFLGIGGSGG--------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------NTTNTEIGSHNQANIGTSTSAG------------
MAV_4827|M.avium_104 ----------------DDELAYSAVGEEDAESPTVVIEKLFLPE------
MUL_1721|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2116|M.marinum_M --------ADGAAGTLGSAGVTGQIGGFGGAGGTGGAGGADQ--------
Mb0857c|M.bovis_AF2122/97 -------GAGGSGGAASPFGIDIGIGGAGGHGGAGTNGGAGG--------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv GGNGTNGGAGGHGGNGGNGGAQHGDGGVGGKGGAGGSGGAGGNGFDAATL
Mflv_5091|M.gilvum_PYR-GCK GGQG-------------LQGGKGGDGGAGGKGGDADSMGS----------
Mvan_1264|M.vanbaalenii_PYR-1 GGQG-------------LQGGQGGDGGTGGTGGDATSMGE----------
MSMEG_0868|M.smegmatis_MC2_155 AGYGPTTGGKASGTAKAGHGGKASDGGKGGNGGDALVMAAGATG------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------GSAAVGGNAGLAGNAGLAGNAG--------
MAV_4827|M.avium_104 --------------------------DSEPRRRPVLLVGSG---------
MUL_1721|M.ulcerans_Agy99 ---------------------------------------GAGGLGGNGGD
MMAR_2116|M.marinum_M -----------------------SLIGGSSGGGGAGGLGGAGGLGGNGGD
Mb0857c|M.bovis_AF2122/97 -----------------------AGGAGGSSGTVFALDLSWGGAGGNGGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv GSPGADGGMGGNGGKGGDGGKAGDGGAGAAGDVTLAVNQGAGGDGGNGGE
Mflv_5091|M.gilvum_PYR-GCK -------------------------------------AGATGGKGGNGGN
Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------AGATGGKGGNGGN
MSMEG_0868|M.smegmatis_MC2_155 -----------------------VATGNTAIGGNGGAASANGAVGGNGGF
TH_3810|M.thermoresistible__bu ----------------------------------------WGGHGGNGGD
MAB_4284c|M.abscessus_ATCC_199 -------------------------------------LAGNAGLAGNAGL
MAV_4827|M.avium_104 -----------------------------------LAVVGISAVLALEIA
MUL_1721|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2116|M.marinum_M --------------------------------------------------
Mb0857c|M.bovis_AF2122/97 ATTG----------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv VGVGGKGGAGGVSANPALNGSAGANGTAPTSGGNGGNGGAGATPTVAGEN
Mflv_5091|M.gilvum_PYR-GCK GGRGGLFG------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 GGRGSLFG------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 TNIAAIHGSITDSSATSGHGGAA---------------------------
TH_3810|M.thermoresistible__bu TDAD----------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AGNAG---------------------------------------------
MAV_4827|M.avium_104 LAIGIR--------------------------------------------
MUL_1721|M.ulcerans_Agy99 --------------ATGFGMTGGDG---------AMG------------G
MMAR_2116|M.marinum_M --------------ATGFGMTGGDG---------AMGGAGGAAGAAGAAG
Mb0857c|M.bovis_AF2122/97 --------------TGGAGGTGGFA---------VAPDFIGFGAAYGGAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv GGAGGNGGHGGSVGNGGAGGAGGNG---------VAGTGLALNGGNGGNG
Mflv_5091|M.gilvum_PYR-GCK --------------KGGNAGNGAD----------------------GGTG
Mvan_1264|M.vanbaalenii_PYR-1 --------------RGGNAGNGGN----------------------GGTG
MSMEG_0868|M.smegmatis_MC2_155 --------------QGGNGGNGGNGWVQAYDPNGPAGTTIDKGKAAGGNG
TH_3810|M.thermoresistible__bu ---------------GGNGGDGGNG----------------------GSA
MAB_4284c|M.abscessus_ATCC_199 --------------LAGNAGLAGNAG-------------------LAGNA
MAV_4827|M.avium_104 --------------TTGTVALQPTP----------------------NQH
MUL_1721|M.ulcerans_Agy99 AVTVPVNFLAHAGSDGGIGTGG----------------------------
MMAR_2116|M.marinum_M AVTVPVNFLAHAGSDGGIGTGG----------------------------
Mb0857c|M.bovis_AF2122/97 GLGGAATGAGGTGGTGGVGAGGFAALG-----------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv GIGGNGGSAAGTGGDGGKGGNGGAGANGQDFSASANGANGGQGGNGGNGG
Mflv_5091|M.gilvum_PYR-GCK GAGGAGGTGG-TGGAGGTGG------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 GNGGNGGTGG-TGGNGGTGG------------------------------
MSMEG_0868|M.smegmatis_MC2_155 GDGGFNGTGGATGGRGGDGAGASVWKANGQHST-----------------
TH_3810|M.thermoresistible__bu GRGGTGGLRGVFGINGGNGR------------------------------
MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAGLAGNAGLAG----------------------------
MAV_4827|M.avium_104 LIVPTEQAPAPPPVQASAPQPK----------------------------
MUL_1721|M.ulcerans_Agy99 -------------------------NGGLGGNGGAG--------------
MMAR_2116|M.marinum_M -------------------------NGGLGGNGGAGS-------------
Mb0857c|M.bovis_AF2122/97 --------------------------VGVGGAGGAGG-------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv IGGKGGDAFATFAKAGNGGAGGNGGNVGVAGQGGAGGKGAIPAMKGATGA
Mflv_5091|M.gilvum_PYR-GCK -------------------------TGGTGGIGGAGS-------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------------TGGTGGIGGAGS-------------
MSMEG_0868|M.smegmatis_MC2_155 ---------------------GQTDTGGNGGRGGDGG-------------
TH_3810|M.thermoresistible__bu --------------------------AGLGGRGXXXX-------------
MAB_4284c|M.abscessus_ATCC_199 -------------------------NAGLAGNAGLAG-------------
MAV_4827|M.avium_104 --------------------------ISVPEPVAAPKP------------
MUL_1721|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2116|M.marinum_M ----IGTTGTDGTAPTTGGPGGAGGAGGDGGAGGAGIGGVGGGSGGNGGL
Mb0857c|M.bovis_AF2122/97 --AATETGGIGGAGGLGVG--LLGGAGGAGGPGGAAS-AGSGGHGGTGGD
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv DGTAPTSGGDGGNGGNGASPTVAGGNGGDGGKGGSGGNVGNGGNGGAGGN
Mflv_5091|M.gilvum_PYR-GCK TGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKGGTGGTGGAGGTG--
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKGGTGGTGGDGGTG--
MSMEG_0868|M.smegmatis_MC2_155 TFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRGGDGALGGNGGTGGV
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------NAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAG--
MAV_4827|M.avium_104 --LSPPVAAPLPAAPPPAAPPLPEAPPIPAAPPVVPVPVVVPPVPVPVP-
MUL_1721|M.ulcerans_Agy99 --------------------------------GHGGIN--------TGTR
MMAR_2116|M.marinum_M -------------------------GGNGGAGGHGGIN--------TGTG
Mb0857c|M.bovis_AF2122/97 ALGLIG-------------------AGIGGVGGVGGAA--------TDTG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv GAAGQAGTPGPTSGDSGTSGTDGGAGGNGGAGGAGGTL--------AGHG
Mflv_5091|M.gilvum_PYR-GCK -----------------------GDGGTGGTGGTGGTG---------GTG
Mvan_1264|M.vanbaalenii_PYR-1 -----------------------GTGGTGGTGGTGGTG---------GTG
MSMEG_0868|M.smegmatis_MC2_155 GL---------------------GNGGKGGNGGNGGNGGTYVDPSHTGAG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------NAAVAGNAAVAGNA---------AVA
MAV_4827|M.avium_104 -------------------------VRIPVPDPVSPPQ----------LL
MUL_1721|M.ulcerans_Agy99 GTASAS---------------------------------GGTGGNGGAGG
MMAR_2116|M.marinum_M GTASAS---------------------------------GGTGGNGGAGG
Mb0857c|M.bovis_AF2122/97 GNGGAGGSGT-----------------------------GLLGGVGGAGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv GNGGKGGNGGQGGIGGAGERGADGAGPNANGANGENGGSGGNGGDGGAGG
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGAG---------------------------------DGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGAG---------------------------------DGLGGTGG
MSMEG_0868|M.smegmatis_MC2_155 GNGGNGGAGRIR----------------------VNNGTATGTATGGNGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GNAAVGGVLN----------------------------TGVSGAIGGSSH
MAV_4827|M.avium_104 APPRLSVPQP------------------------------VQPPVRVPQP
MUL_1721|M.ulcerans_Agy99 NGGAPG---------AANAIGGQGGQGGIG--------------------
MMAR_2116|M.marinum_M NGGAPG---------AANAIGGQGGQGGIG--------------------
Mb0857c|M.bovis_AF2122/97 HGGG-----------ASVGTGGSGGAGGDG--------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv NGGAGGKAQAAGYTDGATGTGGDGGNGGDGGKAGDGGAGENGLNSGAMLP
Mflv_5091|M.gilvum_PYR-GCK TGG-------------TGGQGGQGGQGG----------------------
Mvan_1264|M.vanbaalenii_PYR-1 TGG-------------TGGFGGQGGQGG----------------------
MSMEG_0868|M.smegmatis_MC2_155 NGGNGD---------ADGHRGGKGGDGGEALIRAT--------------V
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGGAIN-----------ESLGGSGSVGG----------------------
MAV_4827|M.avium_104 PS--------------PPQVGGTVPQSPPQ--------------------
MUL_1721|M.ulcerans_Agy99 -----------GNGGNGGN-------------------------------
MMAR_2116|M.marinum_M -----------GNGGNGGNNTSGID-----------------------TA
Mb0857c|M.bovis_AF2122/97 -------FGFVGAGGNGGNAGTG-------------------------VG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv GGGTVGNPGTGGNGGNGGNAGVGGTGGKAGTGSLTGLDGTDGITPNGGNG
Mflv_5091|M.gilvum_PYR-GCK ---------TGGTGGQGG-LGGGGGTG-----------------------
Mvan_1264|M.vanbaalenii_PYR-1 ---------TGGTGGQGG-LGGVGGTG-----------------------
MSMEG_0868|M.smegmatis_MC2_155 IGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATD
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------STAVGG--------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_1721|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2116|M.marinum_M VGYAGGGGGGGAGGHGGNGGGNGALGGQ----------------------
Mb0857c|M.bovis_AF2122/97 VNGANGGNGGSATGALAAVGGAGAAGGDATSG------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv GNGGNGGKGGTAGNGSGAAGGNGGNGGSGLNGGDAGNGGNGGGALNQAGF
Mflv_5091|M.gilvum_PYR-GCK GQGGTGGTGGQGGTGGTGGTGGTG--------------------------
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTGGQGGTGGTGGTGGTG--------------------------
MSMEG_0868|M.smegmatis_MC2_155 GHGGSGINGGHGGNGGQGTIEANGPSAVASGI------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --GAHTGVGGGVSTGVGVGSHVGG--------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_1721|M.ulcerans_Agy99 -------------------------------------------------G
MMAR_2116|M.marinum_M ----------------------------------------GGTGGTGGTG
Mb0857c|M.bovis_AF2122/97 ---------------------TGGFGGAGG----SARGLIFALGGAGAAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv FGTGGKGGNGGNGGAGMINGGLGGFGGAGGGGAVDVAATTGGAGGNGGAG
Mflv_5091|M.gilvum_PYR-GCK --------------------------GTGGAGGDGGLGGLGGFGGSGGTG
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------GTGGAGGDGGLGGLGGFGGVGGTG
MSMEG_0868|M.smegmatis_MC2_155 --------------------------GAGGNGGDGIDGGLGGNGGDGVVN
TH_3810|M.thermoresistible__bu ---------------------------------------------GGGVG
MAB_4284c|M.abscessus_ATCC_199 -------------------------------------GISESLGGSGSVG
MAV_4827|M.avium_104 ------------------------------------------HQTPPGEG
MUL_1721|M.ulcerans_Agy99 GTASSSNTGPTPSAGTG---------------------------------
MMAR_2116|M.marinum_M GTASSSNTGPTPSAGTG---------------------------------
Mb0857c|M.bovis_AF2122/97 GDASTGVGGPGGPGGTGTASSPFGIAIAIGGAGAQGGAGTSG--------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv GFASTGLGGPGGAGGPGGAGDFASGVGGVGGAGGDGGAGGVGGFGGQGGI
Mflv_5091|M.gilvum_PYR-GCK GQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAG------
Mvan_1264|M.vanbaalenii_PYR-1 GQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAG------
MSMEG_0868|M.smegmatis_MC2_155 TTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGS------
TH_3810|M.thermoresistible__bu AAVRSGNGVFSGGGGTPSAG------------------------------
MAB_4284c|M.abscessus_ATCC_199 GSTAVGGGAHTGVGGGVSTG------------------------------
MAV_4827|M.avium_104 TPPKPDGPGNYGGGHVPTPG------------------------------
MUL_1721|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2116|M.marinum_M --------------------------------------------------
Mb0857c|M.bovis_AF2122/97 -------------------------------------ATGGAGGDGVFEG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv GGEGRTGGNGGSGGDGGGGISLGGNGGLGGNGGVSETGFGGAGGNGGYGG
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_1721|M.ulcerans_Agy99 ----------GGGTGGGGGG-----------GGGGGGGGASASGAVGGTG
MMAR_2116|M.marinum_M ----------GGGTGGGGGGGASASGAVGGTGGGGGGGGAGAAAGTGAVG
Mb0857c|M.bovis_AF2122/97 ----IAVLGLGFGGAAGAGGAATGDGATGGAGGFGGAGAGIANF-LGFSV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv PGGPEGNGGLGGNGGAGGNGGVSTTGGDGGAGGKGGNGGDGGNVGLGGDA
Mflv_5091|M.gilvum_PYR-GCK --------KAGATGAAGASGGKGAQGATGAQGATG------AQGATG-AT
Mvan_1264|M.vanbaalenii_PYR-1 --------TAGVTGASGASGGKGAQGATGAQGATG------AQGATG-AT
MSMEG_0868|M.smegmatis_MC2_155 --------TLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVAT
TH_3810|M.thermoresistible__bu ---------FGVPTTIQFPAGSCTSRAVSREGIMPSSRAASARAGAACAS
MAB_4284c|M.abscessus_ATCC_199 -------VGVGSHVGGGISESLGGSGSVGGSTAVGGGAHTGVGGGVNTGV
MAV_4827|M.avium_104 -----------AGGSGGSGGGHVPTPGAGGSGGSGGG--HVPTPGTGGPG
MUL_1721|M.ulcerans_Agy99 GGGGGGGAGAAAG------------------------------TGAVG--
MMAR_2116|M.marinum_M GGGGGGGAAGGAGGTAGNGGAGGNAIAFAGSTSFSSASGGAGGTGAPGG-
Mb0857c|M.bovis_AF2122/97 LHGGAGGAGGTATGTGGNGGAGGGGGLS----SPVILGIGIGGAGGNGGD
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv GSGGAGGNGGIGTDAGGAGGAGGAGGNGGSSKSTTTGNAGSGGAGGNGGT
Mflv_5091|M.gilvum_PYR-GCK GAAGKAGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGA
Mvan_1264|M.vanbaalenii_PYR-1 GASGAQGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGA
MSMEG_0868|M.smegmatis_MC2_155 GNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGG
TH_3810|M.thermoresistible__bu STSRSRRSFCCSRA------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GVGSHVG-GGISESLGGSGSVG----------------GSTAVGGGAHTS
MAV_4827|M.avium_104 GTGGSGGGHVPTPGAGTPGGSGG---------------GHLPFPGAGSTP
MUL_1721|M.ulcerans_Agy99 -------------------------------GGGGGAAPPAAPVAPPEME
MMAR_2116|M.marinum_M ------------------------------TGGGGGGGPLASTLSIDAGN
Mb0857c|M.bovis_AF2122/97 ALG----------------------LVGVGGNGGNAGTGFGANTGGNGGD
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv GLNGAGGAGGAGGNAGVAGVSFGNAVGGDGGNGGNGGHGGDGTTGGAGGK
Mflv_5091|M.gilvum_PYR-GCK NGSQGAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGG
Mvan_1264|M.vanbaalenii_PYR-1 NGSQGAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGG
MSMEG_0868|M.smegmatis_MC2_155 NGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AIN---------------------------DALGGSGSVGGSTAVGGGAH
MAV_4827|M.avium_104 GGS----------------------------GGGHLPTPGAGTPGGGLGG
MUL_1721|M.ulcerans_Agy99 AREATP--------------------------------------------
MMAR_2116|M.marinum_M GADGVNGGTGGTG----TTSGGSGGTGGGAGGQGGNSFQFVPSAAGGAGQ
Mb0857c|M.bovis_AF2122/97 TTIVVNGMLAPS-----TLGYGGNGVNGGAGG-----TGGKAGVFGAPGQ
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv GGNGSSGAASGSGVVNVTAGHGGNGGNGGNGGNGSAGAGGQGGAGGSAGN
Mflv_5091|M.gilvum_PYR-GCK AGG-----------AGGEGGEGGDGGKGGAGAE--------GGAGGGGGA
Mvan_1264|M.vanbaalenii_PYR-1 AGG-----------AGGEGGEGGAGGAGGDGSE--------GGAGGSGGA
MSMEG_0868|M.smegmatis_MC2_155 NGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TSAINESMNSSINASHSSSMNESFGSSMGSHGAAGTGFEAQGHAQGHASE
MAV_4827|M.avium_104 FGGG-----------HAPAPGGGLGGGGGHAPAPGGGLGGFGGGHSGGGL
MUL_1721|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2116|M.marinum_M SG------------------------------------------------
Mb0857c|M.bovis_AF2122/97 NGLP----------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv GGHGGGATGGDGGNGGNGGNSGNSTGVAGLAGGAAGAGGNGGGTSSAAGH
Mflv_5091|M.gilvum_PYR-GCK GGSGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD-------------
Mvan_1264|M.vanbaalenii_PYR-1 GGSGTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD--------------
MSMEG_0868|M.smegmatis_MC2_155 GGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP-------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TAHTTLPGAEHH--------------------------------------
MAV_4827|M.avium_104 GGLGGGHK------------------------------------------
MUL_1721|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2116|M.marinum_M --------------------------------------------------
Mb0857c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv GGSGGSGGSGTTGGAGAAGGNGGAGAGGGSLSTGQSGGPRRQRWCRWQRR
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_1721|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2116|M.marinum_M --------------------------------------------------
Mb0857c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv RWLGRQRRRRWCRWQRRCRRQRWRWRCRQRRLRRQWRQGRRRCRPWLHRR
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_1721|M.ulcerans_Agy99 ------------------------
MMAR_2116|M.marinum_M ------------------------
Mb0857c|M.bovis_AF2122/97 ------------------------
MLBr_01183|M.leprae_Br4923 ------------------------
Rv3345c|M.tuberculosis_H37Rv RGRQGRRWRQRRFQQRQRSRWQRR
Mflv_5091|M.gilvum_PYR-GCK ------------------------
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------
MSMEG_0868|M.smegmatis_MC2_155 ------------------------
TH_3810|M.thermoresistible__bu ------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------
MAV_4827|M.avium_104 ------------------------