For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. marinum M MMAR_4475 (-)

annotation: PE-PGRS family protein
coordinates: 5495603 - 5497123
length: 506

MSFVLVTPEALSAAAADTARIGSAINAATTAAAAQTTSVVAAAGDEVSAAVATLFGTYGQTYQALAAQAS
TLHQQFENALTAAGSSYAGAEAANAAPLQQTQAAFSTVERDVLSAVNAPSLALTGRPLIGNGADGGPGQA
GGAGGWLYGNGGNGGNGGAGQAGGGGGSAGLLGNGGNGGNGGPGIPGGPGPAGGNGGNGGLLFGNGGAGG
NGGDAYVFGNGQPGGSGGAGGDAHLLGTGGAGGHGGLGSVGAAGTNPSGPYLQAASGTDGLSGSVGQPGG
AGADGNPGQQGGTGGTGGTSGVAAGSGGTGGTGGVGAPGGTGGTGGISISPNQAGGGGTGGTGGIGAPGG
TGGHGGDGGAGGRGGLLFGVGGAGGAGGDGLDGGPGAMGLTGGTGGHGGDNTSSATRPGVGGAGGYGGTG
GTGGTGGTGGNGGNGGAGGAGGLFGQSGAAGAGGTAGAGGAGGTGGTGGVGGTGGTGAGGGGRTGGVGGD
GVTGATGASGQPGASG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_4475--100% (506)PE-PGRS family protein
M. marinum MMMAR_4149-e-14353.25% (539) PE-PGRS family protein
M. marinum MMMAR_1162-e-13952.68% (541) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2878PE_PGRS481e-14150.98% (563) PE-PGRS family protein
M. gilvum PYR-GCKMflv_5091-1e-10144.28% (533) triple helix repeat-containing collagen
M. tuberculosis H37RvRv2853PE_PGRS481e-13950.62% (563) PE-PGRS family protein
M. leprae Br4923MLBr_01183-5e-1340.22% (92) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_4284c-7e-4736.36% (385) hypothetical protein MAB_4284c
M. avium 104MAV_4827-6e-2542.13% (178) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0868-4e-6837.25% (510) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-2e-4338.96% (326) PUTATIVE -
M. ulcerans Agy99MUL_0572-1e-13250.00% (568) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_1264-4e-9742.26% (549) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb2878|M.bovis_AF2122/97            -------------------------------------------------M
Rv2853|M.tuberculosis_H37Rv         -------------------------------------------------M
MMAR_4475|M.marinum_M               -------------------------------------------------M
MUL_0572|M.ulcerans_Agy99           -------------------------------------------------M
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------------------------------------------------M
MAV_4827|M.avium_104                ---------------------------------------------MNIVL
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb2878|M.bovis_AF2122/97            LYVVASPDLMTAAATNLAEIGSAISTANGAAALPTVEVVAAAADEVSTQI
Rv2853|M.tuberculosis_H37Rv         LYVVASPDLMTAAATNLAEIGSAISTANGAAALPTVEVVAAAADEVSTQI
MMAR_4475|M.marinum_M               SFVLVTPEALSAAAADTARIGSAINAATTAAAAQTTSVVAAAGDEVSAAV
MUL_0572|M.ulcerans_Agy99           SYVVAIPDMLASAAADVAGIGSSVGAANTAAVGATTGVMAAADDEVSVAI
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      SIIDFILNLFRDPVEAASYVADPEAALANAGLSAVSAAQVGAVMPVVAES
MAV_4827|M.avium_104                GVSMAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDRVISAI
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155      SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb2878|M.bovis_AF2122/97            AALFGAHARSYQTLSTQAAAFHSRFVQALTTAAASYASVEAANASPLQV-
Rv2853|M.tuberculosis_H37Rv         AALFGAHARSYQTLSTQAAAFHSRFVQALTTAAASYASVEAANASPLQV-
MMAR_4475|M.marinum_M               ATLFGTYGQTYQALAAQASTLHQQFENALTAAGSSYAGAEAANAAPLQQT
MUL_0572|M.ulcerans_Agy99           AALFSGHGQAYQAISAQAAAFHDQFLRALTGAGGAYAAAEAANASPLQAA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      VASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDND
MAV_4827|M.avium_104                LGTREGAADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLA
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155      PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb2878|M.bovis_AF2122/97            -------------------------------------------ALDVINA
Rv2853|M.tuberculosis_H37Rv         -------------------------------------------ALDVINA
MMAR_4475|M.marinum_M               QA---------------------------------AFSTVERDVLSAVNA
MUL_0572|M.ulcerans_Agy99           ----------------------------------------EQEVLAVINA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------------------------------FLSHNDTDFASHNP
MAV_4827|M.avium_104                ---------------------------------------AAALAQNVGGA
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1       S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155      TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb2878|M.bovis_AF2122/97            P-----------------------AQTLLG--------RPLIGNGADGST
Rv2853|M.tuberculosis_H37Rv         P-----------------------AQTLLG--------RPLIGNGADGST
MMAR_4475|M.marinum_M               P-----------------------SLALTG--------RPLIGNGADGG-
MUL_0572|M.ulcerans_Agy99           P-----------------------TNALLG--------RPLIGNGTDGLA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      IAS---------------------GNQVMS----------PSGNVDSFNR
MAV_4827|M.avium_104                MG----------------------YERTAVLLVEPDTATLAVVETSDGSI
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          -QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGG----
Mvan_1264|M.vanbaalenii_PYR-1       -QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGG----
MSMEG_0868|M.smegmatis_MC2_155      -DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGG----
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb2878|M.bovis_AF2122/97            -PGQAGGPGGLLYGNGGNGAAG-GPNQAGGAGGNAGLIGNGGAGG-----
Rv2853|M.tuberculosis_H37Rv         -PGQAGGPGGLLYGNGGNGAAG-GPNQAGGAGGNAGLIGNGGAGG-----
MMAR_4475|M.marinum_M               -PGQAGGAGGWLYGNGGNGGNG-GAGQAGGGGGSAGLLGNGGNGGNGGPG
MUL_0572|M.ulcerans_Agy99           GTGAAGGAGGLLWGNGGNGGSG-AAGQAGGAGGAAGLIGTGGAGG-----
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGPIASGQGSTAVNGDVR
MAV_4827|M.avium_104                PDVYKQQIRAESYGDAAGQLSAMVAGLEKLESLPGGLLLVGSGVDVAPLK
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          -NGLGGGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG---APGVA
Mvan_1264|M.vanbaalenii_PYR-1       -NGLGSGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG---APGVA
MSMEG_0868|M.smegmatis_MC2_155      -VGWAGLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGG-TGGTG
TH_3810|M.thermoresistible__bu      ----VDGDGGSGGRTGLFSKLSRGGDGGDGGLG--------------GNG
Mb2878|M.bovis_AF2122/97            -AGGVGAVGGNGGTGG--LLFGNGGAGGQGGLGLAGINGGSG-----GQG
Rv2853|M.tuberculosis_H37Rv         -AGGVGAVGGKRGTGG--LLFGNGGAGGQGGLGLAGINGGSG-----GQG
MMAR_4475|M.marinum_M               IPGGPGPAGGNGGNGG--LLFGNGGAGGNGGDAYVFGNGQPG-----GSG
MUL_0572|M.ulcerans_Agy99           MGGAGGGAGGMGGSGG--WLLGNGGAGGAGG---VGCAGVSG-----GVG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      DSNIINADHGSNVGVDQSQTRVGGDYTNVSGHGSADIDKSVTVVDDHSQR
MAV_4827|M.avium_104                QVLQTTTFLDVSVAEEPETALARGAALAAANAPLFASSTAALAYAQDPGT
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          GATGATGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------
Mvan_1264|M.vanbaalenii_PYR-1       GATGATGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------
MSMEG_0868|M.smegmatis_MC2_155      GTGGGTGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVL
TH_3810|M.thermoresistible__bu      GHGGGTGIIS--------------------LLSLAGNGGNGG--------
Mb2878|M.bovis_AF2122/97            GHGGNAILFGQ---GGAGGPGGT------GAMGVAGTNPT----------
Rv2853|M.tuberculosis_H37Rv         GHGGNAILFGQ---GGAGGPGGT------GAMGVAGTNPT----------
MMAR_4475|M.marinum_M               GAGGDAHLLGT---GGAGGHGGL------GSVGAAGTNPSG---------
MUL_0572|M.ulcerans_Agy99           GTGGNAMLFGN---GGAGGMGGAGADGAVGAAGTAGTSTSAGGVG-----
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      NTTNINDSFNTDRSTNIGSGNTTNTEIGSHNQANIGTSTSAG--------
MAV_4827|M.avium_104                GAVDQYSLPDYLYVPVDPEPGDD-----ELAYSAVGEEDAES--------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ------AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAA
Mvan_1264|M.vanbaalenii_PYR-1       ------AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTA
MSMEG_0868|M.smegmatis_MC2_155      IAGPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGAN
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb2878|M.bovis_AF2122/97            -------------PIGTAAPGSDGVNQIGNGGNTDLTGGAG---------
Rv2853|M.tuberculosis_H37Rv         -------------PIGTAAPGSDGVNQIGNGGNTDLTGGAG---------
MMAR_4475|M.marinum_M               -------------PYLQAASGTDGLS-----GSVGQPGGAG---------
MUL_0572|M.ulcerans_Agy99           ----GAGWDATAAGVLAATGGDGGDSGGGGAGGNGGAGGAGGHGSALFGA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------------GSAAVGGNAGLAGNAGLAGNAGLAGNAG---------
MAV_4827|M.avium_104                ------PTVVIEKLFLPEDSEPRRRPVLLVGSGLAVVGISAVLALEIALA
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          G-------AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAA
Mvan_1264|M.vanbaalenii_PYR-1       G-------VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAA
MSMEG_0868|M.smegmatis_MC2_155      GGTVDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTAT
TH_3810|M.thermoresistible__bu      ---------------NGYRTTDNNALDGGHGGNG----------------
Mb2878|M.bovis_AF2122/97            --------GDGNAGSTTVNG-----GNGGTGGA-----------------
Rv2853|M.tuberculosis_H37Rv         --------GDGNAGSTTVNG-----GNGGTGGA-----------------
MMAR_4475|M.marinum_M               --------ADGNPGQQGGTG-----GTGGTSGV-----------------
MUL_0572|M.ulcerans_Agy99           DG------ANGNGGAGGAGGNPGAPGNGGTGGVG------------PDAA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------LAGNAGLAGNAGLAGNAGLAGNAGLAG----------NAGLA
MAV_4827|M.avium_104                IG----IRTTGTVALQPTPNQHLIVPTEQAPAPP--------------PV
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          GGAGGLGETGTTGGAGGVG--------------------GQGTAGGTGGV
Mvan_1264|M.vanbaalenii_PYR-1       GQAGTAGETGVTGGVGGIG--------------------GQGTEGGTGGV
MSMEG_0868|M.smegmatis_MC2_155      GGDGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGA
TH_3810|M.thermoresistible__bu      -GNVGFFSLFNLGGAGGWG--------------------GSGVDG-----
Mb2878|M.bovis_AF2122/97            ARNSSGGTGNSFGGAGGAG--------------------GDGANG-----
Rv2853|M.tuberculosis_H37Rv         ARNSSGGTGNSFGGAGGAG--------------------GDGANG-----
MMAR_4475|M.marinum_M               AAGS--------GGTGGTG--------------------GVGAPG-----
MUL_0572|M.ulcerans_Agy99           TSGGMGGTGGDPGAVGGRG--------------------NSGAAGGAGAV
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GNAGLAGNAGLAGNAGLAG--------------------NAGLAG-----
MAV_4827|M.avium_104                QASAPQPKISVPEPVAAPKP------------------LSPPVAAPLP--
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          GGIGGAG----------STGAVGG-------VGGKG----IQGGQG----
Mvan_1264|M.vanbaalenii_PYR-1       GGVGGVG----------ATGGAGG-------VGGKG----IQGGQG----
MSMEG_0868|M.smegmatis_MC2_155      GGMGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTG
TH_3810|M.thermoresistible__bu      ------------------VDVVGG--------------------------
Mb2878|M.bovis_AF2122/97            -----------------GDGGAGGEALTEGGAT-----------------
Rv2853|M.tuberculosis_H37Rv         -----------------GDGGAGGEALTEGGAT-----------------
MMAR_4475|M.marinum_M               -----------------GTGGTGGISISP---------------------
MUL_0572|M.ulcerans_Agy99           AGASGAAGTI--IAGNGGNGGAGGAGYAADGPAGPAIGNGGDGGHG----
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----------------NAGLAGNAGLAG---------------------
MAV_4827|M.avium_104                -----------------AAPPPAAPPLPEAPPIPAAP-------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ---------LQGGKGGDGGAGGKGGDADSMGS------------------
Mvan_1264|M.vanbaalenii_PYR-1       ---------LQGGQGGDGGTGGTGGDATSMGE------------------
MSMEG_0868|M.smegmatis_MC2_155      GKASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGA
TH_3810|M.thermoresistible__bu      --------------NPDGGTPG----------------------------
Mb2878|M.bovis_AF2122/97            ---------------AVSGAGGKGGNA-----------------------
Rv2853|M.tuberculosis_H37Rv         ---------------AVSGAGGKGGNA-----------------------
MMAR_4475|M.marinum_M               -----------------NQAGG----------------------------
MUL_0572|M.ulcerans_Agy99           ---------GAGGFYGNGGAGGAGGNS-----------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------------NAGLAGNAGLAGNAG----------------------
MAV_4827|M.avium_104                ---------------PVVPVPVVVPPVP----------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          AGATGGKGGNGGNGGRGGLFG---------------KGGNAGNGAD----
Mvan_1264|M.vanbaalenii_PYR-1       AGATGGKGGNGGNGGRGSLFG---------------RGGNAGNGGN----
MSMEG_0868|M.smegmatis_MC2_155      ASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQ
TH_3810|M.thermoresistible__bu      --AHGESHTPGVYTDRQ---------------------------------
Mb2878|M.bovis_AF2122/97            -EASGGAGGNGGKGGFAQATTSV---------------------------
Rv2853|M.tuberculosis_H37Rv         -EASGGAGGNGGKGGFAQATTSV---------------------------
MMAR_4475|M.marinum_M               ----GGTGGTGGIG------------------------------------
MUL_0572|M.ulcerans_Agy99           -APGGGTGGNGGTGGDSGAMGSSG-----------GRGGDGGVGTNG---
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      LAGNAGLAGNAGLAGNAGLAGN----------------------------
MAV_4827|M.avium_104                VPVPVRIPVPDPVSPPQLLAPPR---------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ------------------GGTGGAGGAGGTGG-TGGAGGTGG--------
Mvan_1264|M.vanbaalenii_PYR-1       ------------------GGTGGNGGNGGTGG-TGGNGGTGG--------
MSMEG_0868|M.smegmatis_MC2_155      AYDPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKAN
TH_3810|M.thermoresistible__bu      ----------------------GEDGEDGTGTGIGGRGGNGG--------
Mb2878|M.bovis_AF2122/97            -----------------TGGNGGNGGNGHDSNAPGGAGGSGGV-------
Rv2853|M.tuberculosis_H37Rv         -----------------TGGNGGNGGNGHDSNAPGGAGGSGGV-------
MMAR_4475|M.marinum_M               --------------------------------APGGTGGHGGD-------
MUL_0572|M.ulcerans_Agy99           ----------------GAGGGGGNATSYGTANATGGAGGDGGTGS-----
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------------AAVAGNAAVAGNAAVAGNAAVGGVLN------
MAV_4827|M.avium_104                ------------------------LSVPQPVQPPVRVPQPPSPPQ-----
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          ---------TGGTGGIG--GAGSTGGTGGTGGTGGTGGTGGTG-GTGGTG
Mvan_1264|M.vanbaalenii_PYR-1       ---------TGGTGGIG--GAGSTGGTGGTGGTGGTGGTGGTG-GTGGTG
MSMEG_0868|M.smegmatis_MC2_155      GQHSTGQTDTGGNGGRG--GDGGTFVNAGANGNGGAGGAGGVSEGEGGTG
TH_3810|M.thermoresistible__bu      --------SSSGTHPMA--EDG--------EHVKALDGRPGLD---GGNG
Mb2878|M.bovis_AF2122/97            ----------GGDGGRG--------------------------------G
Rv2853|M.tuberculosis_H37Rv         ----------GGDGGRG--------------------------------G
MMAR_4475|M.marinum_M               ----------GGAGGRG--------------------------------G
MUL_0572|M.ulcerans_Agy99           ----TGNGGSGGDGGNGGTGHGGGGGPGGTAINYGAGDAFGGAAGKGGTG
MLBr_01183|M.leprae_Br4923          ------------------------------------------------MP
MAB_4284c|M.abscessus_ATCC_199      ---------TGVSGAIG----------------GSSHVGGAINESLGGSG
MAV_4827|M.avium_104                ---------VGGTVPQS-------------------------------PP
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          GTGGTGGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG----------
Mvan_1264|M.vanbaalenii_PYR-1       GTGGTGGKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG----------
MSMEG_0868|M.smegmatis_MC2_155      GHGGDGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVD--PSH
TH_3810|M.thermoresistible__bu      SHGGNGGHGGRGGFLGIGGSG-------GWGGHGGNGGD-----------
Mb2878|M.bovis_AF2122/97            LLAGNGGTGGAGGNGGTGGAG-------APGGAGGAGGKADIANSLGDNA
Rv2853|M.tuberculosis_H37Rv         LLAGNGGTGGAGGNGGTGGAG-------APGGAGGAGGKADIANSLGDNA
MMAR_4475|M.marinum_M               LLFGVGGAGGAGGDGLDGGPG-------AMG-------------------
MUL_0572|M.ulcerans_Agy99           VVGGNGGSGGAAYNYGTGNAT-------GAGGSSGSGGAASVPNS-ASTA
MLBr_01183|M.leprae_Br4923          LFLNAEPQALTAAANTLEGLS-----------------------------
MAB_4284c|M.abscessus_ATCC_199      SVGGSTAVGGGAHTGVGGGVS------TGVGVGSHVGGG-----------
MAV_4827|M.avium_104                QHQTPPGEGTPPKPDGPGNYG---------------GGHVP---------
                                            .         .                               

Mflv_5091|M.gilvum_PYR-GCK          -GTGGTGGTGGAG--------------------------------DGTGG
Mvan_1264|M.vanbaalenii_PYR-1       -GTGGTGGTGGAG--------------------------------DGLGG
MSMEG_0868|M.smegmatis_MC2_155      TGAGGNGGNGGAGRIRVNNGT---------------------ATGTATGG
TH_3810|M.thermoresistible__bu      --TDADGGNGGDG------------------------------------G
Mb2878|M.bovis_AF2122/97            TVTGGNGGTGGDGGS-----------------------------ALGTGG
Rv2853|M.tuberculosis_H37Rv         TVTGGNGGTGGDGGS-----------------------------ALGTGG
MMAR_4475|M.marinum_M               -LTGGTGGHGGDNTS-----------------------------SATRPG
MUL_0572|M.ulcerans_Agy99           TATSGSGGAGGDGTDGGNGGSGGFAFTFGTGNIIAGVGGGGGTGSTGVGG
MLBr_01183|M.leprae_Br4923          --AATVASNAAAAQL-----------------------------------
MAB_4284c|M.abscessus_ATCC_199      -ISESLGGSGSVG------------------------------------G
MAV_4827|M.avium_104                --TPGAGGSGGSG-----------------------------------GG
                                      :   .. ..                                       

Mflv_5091|M.gilvum_PYR-GCK          TGGTGG----TGGQGGQGGQGG-----------------TGGTGGQGG-L
Mvan_1264|M.vanbaalenii_PYR-1       TGGTGG----TGGFGGQGGQGG-----------------TGGTGGQGG-L
MSMEG_0868|M.smegmatis_MC2_155      NGGNGGNGDADGHRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTL
TH_3810|M.thermoresistible__bu      NGGSAG---------------------------------RGGTGGLRGVF
Mb2878|M.bovis_AF2122/97            AGGAGG---------------------------------LGGHGGAGGLL
Rv2853|M.tuberculosis_H37Rv         AGGAGG---------------------------------LGGHGGAGGLL
MMAR_4475|M.marinum_M               VGGAGG---------------------------------YGGTGGTG---
MUL_0572|M.ulcerans_Agy99           IGGSGGGADINNGAFTVVPQGG-----------------AGGHGGDGATD
MLBr_01183|M.leprae_Br4923          TTEIAP---------------------------------PAADDVSILLA
MAB_4284c|M.abscessus_ATCC_199      STAVGG----------------------------------GAHTGVGGGV
MAV_4827|M.avium_104                HVPTPG---------------------------------AGGSGGSGGGH
                                                                            ..        

Mflv_5091|M.gilvum_PYR-GCK          GGGGGTG-----------------------GQGGTGGTGGQGGTGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1       GGVGGTG-----------------------GTGGTGGTGGQGGTGGTGGT
MSMEG_0868|M.smegmatis_MC2_155      GATNGTGGAATIVAYNVVQANPQASGTATDGHGGSGINGGHGGNGGQGTI
TH_3810|M.thermoresistible__bu      GINGGNG------------------------RAGLGGRGXXXXGGGVGAA
Mb2878|M.bovis_AF2122/97            IGNGGAG-----------------------------GAGGLGGAGGAG--
Rv2853|M.tuberculosis_H37Rv         IGNGGAG-----------------------------GAGGLGGAGGAG--
MMAR_4475|M.marinum_M               -GTGGTG-----------------------------GNGGNGGAGGAG--
MUL_0572|M.ulcerans_Agy99           GGAGGAGGFTEI-------------DSSASVIAATGGAGGDGGSGGTGRG
MLBr_01183|M.leprae_Br4923          HFFSGHG----------------------------RQYQAHASQGATN--
MAB_4284c|M.abscessus_ATCC_199      STGVGVG-----------------------SHVGGGISESLGGSGSVGGS
MAV_4827|M.avium_104                VPTPGTG-----------------------------GPGGTGGSGGGHVP
                                        * *                                     *.    

Mflv_5091|M.gilvum_PYR-GCK          GGTG--------GTGGAGGDGGLGGLGGFGGSGGTGGQGGLGGPGGSTGG
Mvan_1264|M.vanbaalenii_PYR-1       GGTG--------GTGGAGGDGGLGGLGGFGGVGGTGGQGGQGGPGGSTGG
MSMEG_0868|M.smegmatis_MC2_155      EANGPSAVASGIGAGGNGGDGIDGGLGGNGGDGVVNTTANAANPGSATGT
TH_3810|M.thermoresistible__bu      VRSG---------------NGVFSGGGGTPSAGFGVPTTIQFPAGSCTSR
Mb2878|M.bovis_AF2122/97            ------------------GAGGEGGAGGAGGEAIPGGASTNSAGGDGGAG
Rv2853|M.tuberculosis_H37Rv         ------------------GAGGEGGAGGAGGEAIPGGASTNSAGGDGGAG
MMAR_4475|M.marinum_M               ------------------GLFGQSGAAGAG--------------GTAGAG
MUL_0572|M.ulcerans_Agy99           GTGG--------------GGTGGGGTGGGGGVGINNG-SGEAIGGAPGAG
MLBr_01183|M.leprae_Br4923          ------------------HQDLIQSLLTSSS----------AYAGTETAN
MAB_4284c|M.abscessus_ATCC_199      TAVG---------------GGAHTGVGGGVNTGVGVGSHVGGGISESLGG
MAV_4827|M.avium_104                -------------------TPGAGTPGGSGGGHLPFPGAGSTPGGSGGGH
                                                                                .   . 

Mflv_5091|M.gilvum_PYR-GCK          AGGAGG--QAGTAGKGGLFG----GSGSAGKAGATGAAGASGGKGAQGAT
Mvan_1264|M.vanbaalenii_PYR-1       AGGAGG--QAGVAGKGGLFG----GSGSAGTAGVTGASGASGGKGAQGAT
MSMEG_0868|M.smegmatis_MC2_155      ATGGDGGKATGTASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASN
TH_3810|M.thermoresistible__bu      AVSREG------------------------IMPSSRAASARAG-------
Mb2878|M.bovis_AF2122/97            GTGGNG--------------------------GDGGAGGAPGLGGAGGAG
Rv2853|M.tuberculosis_H37Rv         GTGGNG--------------------------GDGGAGGAPGLGGAGGAG
MMAR_4475|M.marinum_M               GAGGTG--------------------------GTGGVGG-----------
MUL_0572|M.ulcerans_Agy99           GTGAVG--------------------------GDGGQGGAAYSYGTGDAT
MLBr_01183|M.leprae_Br4923          HDSL----------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      SGSVGG---------------------------STAVGGGAHTSAINDAL
MAV_4827|M.avium_104                LPTPGAG------------------------TPGGGLGGFGGG-------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          GAQGATG------AQGATG-ATGAAGKAGATGAAGAAGAAGSAG------
Mvan_1264|M.vanbaalenii_PYR-1       GAQGATG------AQGATG-ATGASGAQGSAGSAGSAGVAGSAG------
MSMEG_0868|M.smegmatis_MC2_155      GGVAGNGGNALVMAAGTTGVATGNTATGGDGGAATTAGATGGAGGFSNIA
TH_3810|M.thermoresistible__bu      --------------------AACASSTSRSRRSFCCSRA-----------
Mb2878|M.bovis_AF2122/97            GWL--IG-------------QSGSTGGGGAGGAG----------------
Rv2853|M.tuberculosis_H37Rv         GWL--IG-------------QSGSTGGGGAGGAG----------------
MMAR_4475|M.marinum_M               ------------------------TGGTGAGGGG----------------
MUL_0572|M.ulcerans_Agy99           GSAGAAG-------------TAGTTGVGGTGGAGGAAYTLNGAS------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GGSGSVG---------------GSTAVGGGAHTSAINES-----------
MAV_4827|M.avium_104                ---------------------HAPAPGGGLGGGGGHAPAP----------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          -----TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG--------
Mvan_1264|M.vanbaalenii_PYR-1       -----TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG--------
MSMEG_0868|M.smegmatis_MC2_155      AIHGAITDSTAISGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb2878|M.bovis_AF2122/97            -------GAGGAGGAGG---------------------------------
Rv2853|M.tuberculosis_H37Rv         -------GAGGAGGAGG---------------------------------
MMAR_4475|M.marinum_M               -------RTGGVGGDGV---------------------------------
MUL_0572|M.ulcerans_Agy99           ----TATATGGIGGNGGDGGTANGSNGGNGGAGGYAST------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --MNSSINASHSSS------------------------------------
MAV_4827|M.avium_104                --------GGGLGGFGG---------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          AAGEDGDAGSGGSG-INGGAGGAGG-----------AGGEGGEGGDGGKG
Mvan_1264|M.vanbaalenii_PYR-1       AAGDAGDPGSEAVD-INGGAGGAGG-----------AGGEGGEGGAGGAG
MSMEG_0868|M.smegmatis_MC2_155      VAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb2878|M.bovis_AF2122/97            --------------------------------------------------
Rv2853|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4475|M.marinum_M               --------------------------------------------------
MUL_0572|M.ulcerans_Agy99           ------------------------------------TGTGTASVGNGGRG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          GAGAE--------GGAGGGGGAGGSGAGGAG--GAGGSGGSGGSGGSGGS
Mvan_1264|M.vanbaalenii_PYR-1       GDGSE--------GGAGGSGGAGGSGTGGAG--GAGGSGGSGGSGGAGGS
MSMEG_0868|M.smegmatis_MC2_155      GDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTPGT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
Mb2878|M.bovis_AF2122/97            -------------SGGAGGHGDTTSGKNGS--SGTAGFDGNPGQPG----
Rv2853|M.tuberculosis_H37Rv         -------------SGGAGGHGDTTSGKNGS--SGTAGFDGNPGQPG----
MMAR_4475|M.marinum_M               -------------TGATG-----ASGQPGA--SG----------------
MUL_0572|M.ulcerans_Agy99           GDGTA-----TVATGGTGGVGGNAHAPAGSPVPGVGGKGGNPGPGGKPGP
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------------MNESFGSSMGSHGAAGTGFEAQGHAQGHASETAHTTL
MAV_4827|M.avium_104                -------------GHSGGGLGGLGGGHK----------------------
                                                                                      

Mflv_5091|M.gilvum_PYR-GCK          GGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1       GGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155      AGTTGANNP
TH_3810|M.thermoresistible__bu      ---------
Mb2878|M.bovis_AF2122/97            ---------
Rv2853|M.tuberculosis_H37Rv         ---------
MMAR_4475|M.marinum_M               ---------
MUL_0572|M.ulcerans_Agy99           NGADGIVV-
MLBr_01183|M.leprae_Br4923          ---------
MAB_4284c|M.abscessus_ATCC_199      PGAEHH---
MAV_4827|M.avium_104                ---------