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MSFVLVTPEALSAAAADTARIGSAINAATTAAAAQTTSVVAAAGDEVSAAVATLFGTYGQTYQALAAQAS TLHQQFENALTAAGSSYAGAEAANAAPLQQTQAAFSTVERDVLSAVNAPSLALTGRPLIGNGADGGPGQA GGAGGWLYGNGGNGGNGGAGQAGGGGGSAGLLGNGGNGGNGGPGIPGGPGPAGGNGGNGGLLFGNGGAGG NGGDAYVFGNGQPGGSGGAGGDAHLLGTGGAGGHGGLGSVGAAGTNPSGPYLQAASGTDGLSGSVGQPGG AGADGNPGQQGGTGGTGGTSGVAAGSGGTGGTGGVGAPGGTGGTGGISISPNQAGGGGTGGTGGIGAPGG TGGHGGDGGAGGRGGLLFGVGGAGGAGGDGLDGGPGAMGLTGGTGGHGGDNTSSATRPGVGGAGGYGGTG GTGGTGGTGGNGGNGGAGGAGGLFGQSGAAGAGGTAGAGGAGGTGGTGGVGGTGGTGAGGGGRTGGVGGD GVTGATGASGQPGASG
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_4475 | - | - | 100% (506) | PE-PGRS family protein |
M. marinum M | MMAR_4149 | - | e-143 | 53.25% (539) | PE-PGRS family protein |
M. marinum M | MMAR_1162 | - | e-139 | 52.68% (541) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2878 | PE_PGRS48 | 1e-141 | 50.98% (563) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_5091 | - | 1e-101 | 44.28% (533) | triple helix repeat-containing collagen |
M. tuberculosis H37Rv | Rv2853 | PE_PGRS48 | 1e-139 | 50.62% (563) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01183 | - | 5e-13 | 40.22% (92) | hypothetical protein MLBr_01183 |
M. abscessus ATCC 19977 | MAB_4284c | - | 7e-47 | 36.36% (385) | hypothetical protein MAB_4284c |
M. avium 104 | MAV_4827 | - | 6e-25 | 42.13% (178) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_0868 | - | 4e-68 | 37.25% (510) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_3810 | - | 2e-43 | 38.96% (326) | PUTATIVE - |
M. ulcerans Agy99 | MUL_0572 | - | 1e-132 | 50.00% (568) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_1264 | - | 4e-97 | 42.26% (549) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES TH_3810|M.thermoresistible__bu -------------------------------------------------- Mb2878|M.bovis_AF2122/97 -------------------------------------------------M Rv2853|M.tuberculosis_H37Rv -------------------------------------------------M MMAR_4475|M.marinum_M -------------------------------------------------M MUL_0572|M.ulcerans_Agy99 -------------------------------------------------M MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------M MAV_4827|M.avium_104 ---------------------------------------------MNIVL Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP-- MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT TH_3810|M.thermoresistible__bu -------------------------------------------------- Mb2878|M.bovis_AF2122/97 LYVVASPDLMTAAATNLAEIGSAISTANGAAALPTVEVVAAAADEVSTQI Rv2853|M.tuberculosis_H37Rv LYVVASPDLMTAAATNLAEIGSAISTANGAAALPTVEVVAAAADEVSTQI MMAR_4475|M.marinum_M SFVLVTPEALSAAAADTARIGSAINAATTAAAAQTTSVVAAAGDEVSAAV MUL_0572|M.ulcerans_Agy99 SYVVAIPDMLASAAADVAGIGSSVGAANTAAVGATTGVMAAADDEVSVAI MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 SIIDFILNLFRDPVEAASYVADPEAALANAGLSAVSAAQVGAVMPVVAES MAV_4827|M.avium_104 GVSMAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDRVISAI Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA TH_3810|M.thermoresistible__bu -------------------------------------------------- Mb2878|M.bovis_AF2122/97 AALFGAHARSYQTLSTQAAAFHSRFVQALTTAAASYASVEAANASPLQV- Rv2853|M.tuberculosis_H37Rv AALFGAHARSYQTLSTQAAAFHSRFVQALTTAAASYASVEAANASPLQV- MMAR_4475|M.marinum_M ATLFGTYGQTYQALAAQASTLHQQFENALTAAGSSYAGAEAANAAPLQQT MUL_0572|M.ulcerans_Agy99 AALFSGHGQAYQAISAQAAAFHDQFLRALTGAGGAYAAAEAANASPLQAA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 VASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDND MAV_4827|M.avium_104 LGTREGAADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLA Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP TH_3810|M.thermoresistible__bu -------------------------------------------------- Mb2878|M.bovis_AF2122/97 -------------------------------------------ALDVINA Rv2853|M.tuberculosis_H37Rv -------------------------------------------ALDVINA MMAR_4475|M.marinum_M QA---------------------------------AFSTVERDVLSAVNA MUL_0572|M.ulcerans_Agy99 ----------------------------------------EQEVLAVINA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ------------------------------------FLSHNDTDFASHNP MAV_4827|M.avium_104 ---------------------------------------AAALAQNVGGA Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA TH_3810|M.thermoresistible__bu -------------------------------------------------- Mb2878|M.bovis_AF2122/97 P-----------------------AQTLLG--------RPLIGNGADGST Rv2853|M.tuberculosis_H37Rv P-----------------------AQTLLG--------RPLIGNGADGST MMAR_4475|M.marinum_M P-----------------------SLALTG--------RPLIGNGADGG- MUL_0572|M.ulcerans_Agy99 P-----------------------TNALLG--------RPLIGNGTDGLA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 IAS---------------------GNQVMS----------PSGNVDSFNR MAV_4827|M.avium_104 MG----------------------YERTAVLLVEPDTATLAVVETSDGSI Mflv_5091|M.gilvum_PYR-GCK -QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGG---- Mvan_1264|M.vanbaalenii_PYR-1 -QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGG---- MSMEG_0868|M.smegmatis_MC2_155 -DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGG---- TH_3810|M.thermoresistible__bu -------------------------------------------------- Mb2878|M.bovis_AF2122/97 -PGQAGGPGGLLYGNGGNGAAG-GPNQAGGAGGNAGLIGNGGAGG----- Rv2853|M.tuberculosis_H37Rv -PGQAGGPGGLLYGNGGNGAAG-GPNQAGGAGGNAGLIGNGGAGG----- MMAR_4475|M.marinum_M -PGQAGGAGGWLYGNGGNGGNG-GAGQAGGGGGSAGLLGNGGNGGNGGPG MUL_0572|M.ulcerans_Agy99 GTGAAGGAGGLLWGNGGNGGSG-AAGQAGGAGGAAGLIGTGGAGG----- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGPIASGQGSTAVNGDVR MAV_4827|M.avium_104 PDVYKQQIRAESYGDAAGQLSAMVAGLEKLESLPGGLLLVGSGVDVAPLK Mflv_5091|M.gilvum_PYR-GCK -NGLGGGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG---APGVA Mvan_1264|M.vanbaalenii_PYR-1 -NGLGSGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG---APGVA MSMEG_0868|M.smegmatis_MC2_155 -VGWAGLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGG-TGGTG TH_3810|M.thermoresistible__bu ----VDGDGGSGGRTGLFSKLSRGGDGGDGGLG--------------GNG Mb2878|M.bovis_AF2122/97 -AGGVGAVGGNGGTGG--LLFGNGGAGGQGGLGLAGINGGSG-----GQG Rv2853|M.tuberculosis_H37Rv -AGGVGAVGGKRGTGG--LLFGNGGAGGQGGLGLAGINGGSG-----GQG MMAR_4475|M.marinum_M IPGGPGPAGGNGGNGG--LLFGNGGAGGNGGDAYVFGNGQPG-----GSG MUL_0572|M.ulcerans_Agy99 MGGAGGGAGGMGGSGG--WLLGNGGAGGAGG---VGCAGVSG-----GVG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 DSNIINADHGSNVGVDQSQTRVGGDYTNVSGHGSADIDKSVTVVDDHSQR MAV_4827|M.avium_104 QVLQTTTFLDVSVAEEPETALARGAALAAANAPLFASSTAALAYAQDPGT Mflv_5091|M.gilvum_PYR-GCK GATGATGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG-------- Mvan_1264|M.vanbaalenii_PYR-1 GATGATGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG-------- MSMEG_0868|M.smegmatis_MC2_155 GTGGGTGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVL TH_3810|M.thermoresistible__bu GHGGGTGIIS--------------------LLSLAGNGGNGG-------- Mb2878|M.bovis_AF2122/97 GHGGNAILFGQ---GGAGGPGGT------GAMGVAGTNPT---------- Rv2853|M.tuberculosis_H37Rv GHGGNAILFGQ---GGAGGPGGT------GAMGVAGTNPT---------- MMAR_4475|M.marinum_M GAGGDAHLLGT---GGAGGHGGL------GSVGAAGTNPSG--------- MUL_0572|M.ulcerans_Agy99 GTGGNAMLFGN---GGAGGMGGAGADGAVGAAGTAGTSTSAGGVG----- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 NTTNINDSFNTDRSTNIGSGNTTNTEIGSHNQANIGTSTSAG-------- MAV_4827|M.avium_104 GAVDQYSLPDYLYVPVDPEPGDD-----ELAYSAVGEEDAES-------- Mflv_5091|M.gilvum_PYR-GCK ------AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAA Mvan_1264|M.vanbaalenii_PYR-1 ------AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTA MSMEG_0868|M.smegmatis_MC2_155 IAGPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGAN TH_3810|M.thermoresistible__bu -------------------------------------------------- Mb2878|M.bovis_AF2122/97 -------------PIGTAAPGSDGVNQIGNGGNTDLTGGAG--------- Rv2853|M.tuberculosis_H37Rv -------------PIGTAAPGSDGVNQIGNGGNTDLTGGAG--------- MMAR_4475|M.marinum_M -------------PYLQAASGTDGLS-----GSVGQPGGAG--------- MUL_0572|M.ulcerans_Agy99 ----GAGWDATAAGVLAATGGDGGDSGGGGAGGNGGAGGAGGHGSALFGA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------GSAAVGGNAGLAGNAGLAGNAGLAGNAG--------- MAV_4827|M.avium_104 ------PTVVIEKLFLPEDSEPRRRPVLLVGSGLAVVGISAVLALEIALA Mflv_5091|M.gilvum_PYR-GCK G-------AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAA Mvan_1264|M.vanbaalenii_PYR-1 G-------VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAA MSMEG_0868|M.smegmatis_MC2_155 GGTVDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTAT TH_3810|M.thermoresistible__bu ---------------NGYRTTDNNALDGGHGGNG---------------- Mb2878|M.bovis_AF2122/97 --------GDGNAGSTTVNG-----GNGGTGGA----------------- Rv2853|M.tuberculosis_H37Rv --------GDGNAGSTTVNG-----GNGGTGGA----------------- MMAR_4475|M.marinum_M --------ADGNPGQQGGTG-----GTGGTSGV----------------- MUL_0572|M.ulcerans_Agy99 DG------ANGNGGAGGAGGNPGAPGNGGTGGVG------------PDAA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --------LAGNAGLAGNAGLAGNAGLAGNAGLAG----------NAGLA MAV_4827|M.avium_104 IG----IRTTGTVALQPTPNQHLIVPTEQAPAPP--------------PV Mflv_5091|M.gilvum_PYR-GCK GGAGGLGETGTTGGAGGVG--------------------GQGTAGGTGGV Mvan_1264|M.vanbaalenii_PYR-1 GQAGTAGETGVTGGVGGIG--------------------GQGTEGGTGGV MSMEG_0868|M.smegmatis_MC2_155 GGDGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGA TH_3810|M.thermoresistible__bu -GNVGFFSLFNLGGAGGWG--------------------GSGVDG----- Mb2878|M.bovis_AF2122/97 ARNSSGGTGNSFGGAGGAG--------------------GDGANG----- Rv2853|M.tuberculosis_H37Rv ARNSSGGTGNSFGGAGGAG--------------------GDGANG----- MMAR_4475|M.marinum_M AAGS--------GGTGGTG--------------------GVGAPG----- MUL_0572|M.ulcerans_Agy99 TSGGMGGTGGDPGAVGGRG--------------------NSGAAGGAGAV MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GNAGLAGNAGLAGNAGLAG--------------------NAGLAG----- MAV_4827|M.avium_104 QASAPQPKISVPEPVAAPKP------------------LSPPVAAPLP-- Mflv_5091|M.gilvum_PYR-GCK GGIGGAG----------STGAVGG-------VGGKG----IQGGQG---- Mvan_1264|M.vanbaalenii_PYR-1 GGVGGVG----------ATGGAGG-------VGGKG----IQGGQG---- MSMEG_0868|M.smegmatis_MC2_155 GGMGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTG TH_3810|M.thermoresistible__bu ------------------VDVVGG-------------------------- Mb2878|M.bovis_AF2122/97 -----------------GDGGAGGEALTEGGAT----------------- Rv2853|M.tuberculosis_H37Rv -----------------GDGGAGGEALTEGGAT----------------- MMAR_4475|M.marinum_M -----------------GTGGTGGISISP--------------------- MUL_0572|M.ulcerans_Agy99 AGASGAAGTI--IAGNGGNGGAGGAGYAADGPAGPAIGNGGDGGHG---- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -----------------NAGLAGNAGLAG--------------------- MAV_4827|M.avium_104 -----------------AAPPPAAPPLPEAPPIPAAP------------- Mflv_5091|M.gilvum_PYR-GCK ---------LQGGKGGDGGAGGKGGDADSMGS------------------ Mvan_1264|M.vanbaalenii_PYR-1 ---------LQGGQGGDGGTGGTGGDATSMGE------------------ MSMEG_0868|M.smegmatis_MC2_155 GKASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGA TH_3810|M.thermoresistible__bu --------------NPDGGTPG---------------------------- Mb2878|M.bovis_AF2122/97 ---------------AVSGAGGKGGNA----------------------- Rv2853|M.tuberculosis_H37Rv ---------------AVSGAGGKGGNA----------------------- MMAR_4475|M.marinum_M -----------------NQAGG---------------------------- MUL_0572|M.ulcerans_Agy99 ---------GAGGFYGNGGAGGAGGNS----------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------NAGLAGNAGLAGNAG---------------------- MAV_4827|M.avium_104 ---------------PVVPVPVVVPPVP---------------------- Mflv_5091|M.gilvum_PYR-GCK AGATGGKGGNGGNGGRGGLFG---------------KGGNAGNGAD---- Mvan_1264|M.vanbaalenii_PYR-1 AGATGGKGGNGGNGGRGSLFG---------------RGGNAGNGGN---- MSMEG_0868|M.smegmatis_MC2_155 ASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQ TH_3810|M.thermoresistible__bu --AHGESHTPGVYTDRQ--------------------------------- Mb2878|M.bovis_AF2122/97 -EASGGAGGNGGKGGFAQATTSV--------------------------- Rv2853|M.tuberculosis_H37Rv -EASGGAGGNGGKGGFAQATTSV--------------------------- MMAR_4475|M.marinum_M ----GGTGGTGGIG------------------------------------ MUL_0572|M.ulcerans_Agy99 -APGGGTGGNGGTGGDSGAMGSSG-----------GRGGDGGVGTNG--- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGNAGLAGNAGLAGN---------------------------- MAV_4827|M.avium_104 VPVPVRIPVPDPVSPPQLLAPPR--------------------------- Mflv_5091|M.gilvum_PYR-GCK ------------------GGTGGAGGAGGTGG-TGGAGGTGG-------- Mvan_1264|M.vanbaalenii_PYR-1 ------------------GGTGGNGGNGGTGG-TGGNGGTGG-------- MSMEG_0868|M.smegmatis_MC2_155 AYDPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKAN TH_3810|M.thermoresistible__bu ----------------------GEDGEDGTGTGIGGRGGNGG-------- Mb2878|M.bovis_AF2122/97 -----------------TGGNGGNGGNGHDSNAPGGAGGSGGV------- Rv2853|M.tuberculosis_H37Rv -----------------TGGNGGNGGNGHDSNAPGGAGGSGGV------- MMAR_4475|M.marinum_M --------------------------------APGGTGGHGGD------- MUL_0572|M.ulcerans_Agy99 ----------------GAGGGGGNATSYGTANATGGAGGDGGTGS----- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ------------------AAVAGNAAVAGNAAVAGNAAVGGVLN------ MAV_4827|M.avium_104 ------------------------LSVPQPVQPPVRVPQPPSPPQ----- Mflv_5091|M.gilvum_PYR-GCK ---------TGGTGGIG--GAGSTGGTGGTGGTGGTGGTGGTG-GTGGTG Mvan_1264|M.vanbaalenii_PYR-1 ---------TGGTGGIG--GAGSTGGTGGTGGTGGTGGTGGTG-GTGGTG MSMEG_0868|M.smegmatis_MC2_155 GQHSTGQTDTGGNGGRG--GDGGTFVNAGANGNGGAGGAGGVSEGEGGTG TH_3810|M.thermoresistible__bu --------SSSGTHPMA--EDG--------EHVKALDGRPGLD---GGNG Mb2878|M.bovis_AF2122/97 ----------GGDGGRG--------------------------------G Rv2853|M.tuberculosis_H37Rv ----------GGDGGRG--------------------------------G MMAR_4475|M.marinum_M ----------GGAGGRG--------------------------------G MUL_0572|M.ulcerans_Agy99 ----TGNGGSGGDGGNGGTGHGGGGGPGGTAINYGAGDAFGGAAGKGGTG MLBr_01183|M.leprae_Br4923 ------------------------------------------------MP MAB_4284c|M.abscessus_ATCC_199 ---------TGVSGAIG----------------GSSHVGGAINESLGGSG MAV_4827|M.avium_104 ---------VGGTVPQS-------------------------------PP Mflv_5091|M.gilvum_PYR-GCK GTGGTGGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------- Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------- MSMEG_0868|M.smegmatis_MC2_155 GHGGDGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVD--PSH TH_3810|M.thermoresistible__bu SHGGNGGHGGRGGFLGIGGSG-------GWGGHGGNGGD----------- Mb2878|M.bovis_AF2122/97 LLAGNGGTGGAGGNGGTGGAG-------APGGAGGAGGKADIANSLGDNA Rv2853|M.tuberculosis_H37Rv LLAGNGGTGGAGGNGGTGGAG-------APGGAGGAGGKADIANSLGDNA MMAR_4475|M.marinum_M LLFGVGGAGGAGGDGLDGGPG-------AMG------------------- MUL_0572|M.ulcerans_Agy99 VVGGNGGSGGAAYNYGTGNAT-------GAGGSSGSGGAASVPNS-ASTA MLBr_01183|M.leprae_Br4923 LFLNAEPQALTAAANTLEGLS----------------------------- MAB_4284c|M.abscessus_ATCC_199 SVGGSTAVGGGAHTGVGGGVS------TGVGVGSHVGGG----------- MAV_4827|M.avium_104 QHQTPPGEGTPPKPDGPGNYG---------------GGHVP--------- . . Mflv_5091|M.gilvum_PYR-GCK -GTGGTGGTGGAG--------------------------------DGTGG Mvan_1264|M.vanbaalenii_PYR-1 -GTGGTGGTGGAG--------------------------------DGLGG MSMEG_0868|M.smegmatis_MC2_155 TGAGGNGGNGGAGRIRVNNGT---------------------ATGTATGG TH_3810|M.thermoresistible__bu --TDADGGNGGDG------------------------------------G Mb2878|M.bovis_AF2122/97 TVTGGNGGTGGDGGS-----------------------------ALGTGG Rv2853|M.tuberculosis_H37Rv TVTGGNGGTGGDGGS-----------------------------ALGTGG MMAR_4475|M.marinum_M -LTGGTGGHGGDNTS-----------------------------SATRPG MUL_0572|M.ulcerans_Agy99 TATSGSGGAGGDGTDGGNGGSGGFAFTFGTGNIIAGVGGGGGTGSTGVGG MLBr_01183|M.leprae_Br4923 --AATVASNAAAAQL----------------------------------- MAB_4284c|M.abscessus_ATCC_199 -ISESLGGSGSVG------------------------------------G MAV_4827|M.avium_104 --TPGAGGSGGSG-----------------------------------GG : .. .. Mflv_5091|M.gilvum_PYR-GCK TGGTGG----TGGQGGQGGQGG-----------------TGGTGGQGG-L Mvan_1264|M.vanbaalenii_PYR-1 TGGTGG----TGGFGGQGGQGG-----------------TGGTGGQGG-L MSMEG_0868|M.smegmatis_MC2_155 NGGNGGNGDADGHRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTL TH_3810|M.thermoresistible__bu NGGSAG---------------------------------RGGTGGLRGVF Mb2878|M.bovis_AF2122/97 AGGAGG---------------------------------LGGHGGAGGLL Rv2853|M.tuberculosis_H37Rv AGGAGG---------------------------------LGGHGGAGGLL MMAR_4475|M.marinum_M VGGAGG---------------------------------YGGTGGTG--- MUL_0572|M.ulcerans_Agy99 IGGSGGGADINNGAFTVVPQGG-----------------AGGHGGDGATD MLBr_01183|M.leprae_Br4923 TTEIAP---------------------------------PAADDVSILLA MAB_4284c|M.abscessus_ATCC_199 STAVGG----------------------------------GAHTGVGGGV MAV_4827|M.avium_104 HVPTPG---------------------------------AGGSGGSGGGH .. Mflv_5091|M.gilvum_PYR-GCK GGGGGTG-----------------------GQGGTGGTGGQGGTGGTGGT Mvan_1264|M.vanbaalenii_PYR-1 GGVGGTG-----------------------GTGGTGGTGGQGGTGGTGGT MSMEG_0868|M.smegmatis_MC2_155 GATNGTGGAATIVAYNVVQANPQASGTATDGHGGSGINGGHGGNGGQGTI TH_3810|M.thermoresistible__bu GINGGNG------------------------RAGLGGRGXXXXGGGVGAA Mb2878|M.bovis_AF2122/97 IGNGGAG-----------------------------GAGGLGGAGGAG-- Rv2853|M.tuberculosis_H37Rv IGNGGAG-----------------------------GAGGLGGAGGAG-- MMAR_4475|M.marinum_M -GTGGTG-----------------------------GNGGNGGAGGAG-- MUL_0572|M.ulcerans_Agy99 GGAGGAGGFTEI-------------DSSASVIAATGGAGGDGGSGGTGRG MLBr_01183|M.leprae_Br4923 HFFSGHG----------------------------RQYQAHASQGATN-- MAB_4284c|M.abscessus_ATCC_199 STGVGVG-----------------------SHVGGGISESLGGSGSVGGS MAV_4827|M.avium_104 VPTPGTG-----------------------------GPGGTGGSGGGHVP * * *. Mflv_5091|M.gilvum_PYR-GCK GGTG--------GTGGAGGDGGLGGLGGFGGSGGTGGQGGLGGPGGSTGG Mvan_1264|M.vanbaalenii_PYR-1 GGTG--------GTGGAGGDGGLGGLGGFGGVGGTGGQGGQGGPGGSTGG MSMEG_0868|M.smegmatis_MC2_155 EANGPSAVASGIGAGGNGGDGIDGGLGGNGGDGVVNTTANAANPGSATGT TH_3810|M.thermoresistible__bu VRSG---------------NGVFSGGGGTPSAGFGVPTTIQFPAGSCTSR Mb2878|M.bovis_AF2122/97 ------------------GAGGEGGAGGAGGEAIPGGASTNSAGGDGGAG Rv2853|M.tuberculosis_H37Rv ------------------GAGGEGGAGGAGGEAIPGGASTNSAGGDGGAG MMAR_4475|M.marinum_M ------------------GLFGQSGAAGAG--------------GTAGAG MUL_0572|M.ulcerans_Agy99 GTGG--------------GGTGGGGTGGGGGVGINNG-SGEAIGGAPGAG MLBr_01183|M.leprae_Br4923 ------------------HQDLIQSLLTSSS----------AYAGTETAN MAB_4284c|M.abscessus_ATCC_199 TAVG---------------GGAHTGVGGGVNTGVGVGSHVGGGISESLGG MAV_4827|M.avium_104 -------------------TPGAGTPGGSGGGHLPFPGAGSTPGGSGGGH . . Mflv_5091|M.gilvum_PYR-GCK AGGAGG--QAGTAGKGGLFG----GSGSAGKAGATGAAGASGGKGAQGAT Mvan_1264|M.vanbaalenii_PYR-1 AGGAGG--QAGVAGKGGLFG----GSGSAGTAGVTGASGASGGKGAQGAT MSMEG_0868|M.smegmatis_MC2_155 ATGGDGGKATGTASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASN TH_3810|M.thermoresistible__bu AVSREG------------------------IMPSSRAASARAG------- Mb2878|M.bovis_AF2122/97 GTGGNG--------------------------GDGGAGGAPGLGGAGGAG Rv2853|M.tuberculosis_H37Rv GTGGNG--------------------------GDGGAGGAPGLGGAGGAG MMAR_4475|M.marinum_M GAGGTG--------------------------GTGGVGG----------- MUL_0572|M.ulcerans_Agy99 GTGAVG--------------------------GDGGQGGAAYSYGTGDAT MLBr_01183|M.leprae_Br4923 HDSL---------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 SGSVGG---------------------------STAVGGGAHTSAINDAL MAV_4827|M.avium_104 LPTPGAG------------------------TPGGGLGGFGGG------- Mflv_5091|M.gilvum_PYR-GCK GAQGATG------AQGATG-ATGAAGKAGATGAAGAAGAAGSAG------ Mvan_1264|M.vanbaalenii_PYR-1 GAQGATG------AQGATG-ATGASGAQGSAGSAGSAGVAGSAG------ MSMEG_0868|M.smegmatis_MC2_155 GGVAGNGGNALVMAAGTTGVATGNTATGGDGGAATTAGATGGAGGFSNIA TH_3810|M.thermoresistible__bu --------------------AACASSTSRSRRSFCCSRA----------- Mb2878|M.bovis_AF2122/97 GWL--IG-------------QSGSTGGGGAGGAG---------------- Rv2853|M.tuberculosis_H37Rv GWL--IG-------------QSGSTGGGGAGGAG---------------- MMAR_4475|M.marinum_M ------------------------TGGTGAGGGG---------------- MUL_0572|M.ulcerans_Agy99 GSAGAAG-------------TAGTTGVGGTGGAGGAAYTLNGAS------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GGSGSVG---------------GSTAVGGGAHTSAINES----------- MAV_4827|M.avium_104 ---------------------HAPAPGGGLGGGGGHAPAP---------- Mflv_5091|M.gilvum_PYR-GCK -----TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG-------- Mvan_1264|M.vanbaalenii_PYR-1 -----TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG-------- MSMEG_0868|M.smegmatis_MC2_155 AIHGAITDSTAISGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSA TH_3810|M.thermoresistible__bu -------------------------------------------------- Mb2878|M.bovis_AF2122/97 -------GAGGAGGAGG--------------------------------- Rv2853|M.tuberculosis_H37Rv -------GAGGAGGAGG--------------------------------- MMAR_4475|M.marinum_M -------RTGGVGGDGV--------------------------------- MUL_0572|M.ulcerans_Agy99 ----TATATGGIGGNGGDGGTANGSNGGNGGAGGYAST------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --MNSSINASHSSS------------------------------------ MAV_4827|M.avium_104 --------GGGLGGFGG--------------------------------- Mflv_5091|M.gilvum_PYR-GCK AAGEDGDAGSGGSG-INGGAGGAGG-----------AGGEGGEGGDGGKG Mvan_1264|M.vanbaalenii_PYR-1 AAGDAGDPGSEAVD-INGGAGGAGG-----------AGGEGGEGGAGGAG MSMEG_0868|M.smegmatis_MC2_155 VAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNG TH_3810|M.thermoresistible__bu -------------------------------------------------- Mb2878|M.bovis_AF2122/97 -------------------------------------------------- Rv2853|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4475|M.marinum_M -------------------------------------------------- MUL_0572|M.ulcerans_Agy99 ------------------------------------TGTGTASVGNGGRG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK GAGAE--------GGAGGGGGAGGSGAGGAG--GAGGSGGSGGSGGSGGS Mvan_1264|M.vanbaalenii_PYR-1 GDGSE--------GGAGGSGGAGGSGTGGAG--GAGGSGGSGGSGGAGGS MSMEG_0868|M.smegmatis_MC2_155 GDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTPGT TH_3810|M.thermoresistible__bu -------------------------------------------------- Mb2878|M.bovis_AF2122/97 -------------SGGAGGHGDTTSGKNGS--SGTAGFDGNPGQPG---- Rv2853|M.tuberculosis_H37Rv -------------SGGAGGHGDTTSGKNGS--SGTAGFDGNPGQPG---- MMAR_4475|M.marinum_M -------------TGATG-----ASGQPGA--SG---------------- MUL_0572|M.ulcerans_Agy99 GDGTA-----TVATGGTGGVGGNAHAPAGSPVPGVGGKGGNPGPGGKPGP MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------MNESFGSSMGSHGAAGTGFEAQGHAQGHASETAHTTL MAV_4827|M.avium_104 -------------GHSGGGLGGLGGGHK---------------------- Mflv_5091|M.gilvum_PYR-GCK GGAAGDSDD Mvan_1264|M.vanbaalenii_PYR-1 GGAAGDSD- MSMEG_0868|M.smegmatis_MC2_155 AGTTGANNP TH_3810|M.thermoresistible__bu --------- Mb2878|M.bovis_AF2122/97 --------- Rv2853|M.tuberculosis_H37Rv --------- MMAR_4475|M.marinum_M --------- MUL_0572|M.ulcerans_Agy99 NGADGIVV- MLBr_01183|M.leprae_Br4923 --------- MAB_4284c|M.abscessus_ATCC_199 PGAEHH--- MAV_4827|M.avium_104 ---------