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MTRPPARIRLRRRLLLFSAVPAVLVTLLAVKLISVVVVGGAAQQHYATGDIGALSDDVSLLQFANMIEPA NAAVAAGGLAVLHDRLDVADMQFTAALETTDDSRSCPVRINLELVRERRGDIDAWEARLDDARQRYEAAL TVIADAPPACFAGNDDPDPQRRAVRADAAARVQAKIDALGTVAPLAPPSPPPPAAPVAPTAPPPAGADQP RPDERRLDIGEDPLAALRQLLRDAAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0044 | - | - | 100% (236) | hypothetical protein Mflv_0044 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0658 | - | 3e-32 | 41.33% (196) | hypothetical protein MAB_0658 |
| M. marinum M | MMAR_5451 | - | 4e-05 | 33.33% (81) | hypothetical protein MMAR_5451 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_6606 | - | 3e-51 | 50.43% (230) | hypothetical protein MSMEG_6606 |
| M. thermoresistible (build 8) | TH_4401 | - | 5e-47 | 54.84% (186) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4315 | dnaZX | 6e-05 | 36.90% (84) | DNA polymerase III subunits gamma and tau |
| M. vanbaalenii PYR-1 | Mvan_0874 | - | 2e-84 | 69.49% (236) | hypothetical protein Mvan_0874 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0044|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0874|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4401|M.thermoresistible__bu --------------------------------------------------
MSMEG_6606|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0658|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4315|M.ulcerans_Agy99 --------------------------------------------------
MMAR_5451|M.marinum_M MPADYDELFQPAEGSGPPDDETGQTFFDPGTAYPPPVKPNGDGHSAPKDW
Mflv_0044|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0874|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4401|M.thermoresistible__bu --------------------------------------------------
MSMEG_6606|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0658|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4315|M.ulcerans_Agy99 ------------------------------------------MALYRKYR
MMAR_5451|M.marinum_M SRAFPPAEDESPSDSAEPAAGPAKSPLPPMPIGGPAPTPPEPPPAPPELP
Mflv_0044|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0874|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4401|M.thermoresistible__bu --------------------------------------------------
MSMEG_6606|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0658|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4315|M.ulcerans_Agy99 PATFAEVVGQEHVTEPLSIALEAGRINHAYLFSGPRGCGKTSSARILARS
MMAR_5451|M.marinum_M PAPPEPPPARPEAPPQAPTAEAEPPDEAIPVSGPPPGGKSPLPPMPIGGP
Mflv_0044|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0874|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4401|M.thermoresistible__bu --------------------------------------------------
MSMEG_6606|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0658|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4315|M.ulcerans_Agy99 LNCAQGPTATPCGTCESCQALAPSAPGSIDVVELDAASHGGVDDTRELRD
MMAR_5451|M.marinum_M PPASPEPPAAPPEPTAPAEPPQPPEAAAQPPQAVEEQAHATAEPPAAPNP
Mflv_0044|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0874|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4401|M.thermoresistible__bu --------------------------------------------------
MSMEG_6606|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0658|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4315|M.ulcerans_Agy99 R-----------AFYAPAQSRYRVFIIDEAHMVTTAGFNALLKIVEEPPE
MMAR_5451|M.marinum_M PRPPMPIGGPPPTPPAAPEPQQDIAEEPAPAAAEAPAAPPKSPLPPMPVS
Mflv_0044|M.gilvum_PYR-GCK ---------------------MTRPPARIRLR---RRLLLFSAVPAVLVT
Mvan_0874|M.vanbaalenii_PYR-1 ---------------------MTRLPARIRLR---RRLLLASAPPALVTV
TH_4401|M.thermoresistible__bu --------------------VTGRLPARVRLR---RRLLIYSAPVAVGVL
MSMEG_6606|M.smegmatis_MC2_155 ------------------------------MR---RRLLVYSAPVAVVTV
MAB_0658|M.abscessus_ATCC_1997 --------MNPRSILVLVQRFFSEGPSRKVLR---RRLVALSVLPALLLL
MUL_4315|M.ulcerans_Agy99 HLIFIFATTEPEKVLPTIRSRTHHYPFRLLPRRTMRGLIGRICEQEGVVV
MMAR_5451|M.marinum_M GPPPEPPELPPAPPEPTASAEPPQPPQSVEEQAHATAEPPAAPKPTRPPM
:
Mflv_0044|M.gilvum_PYR-GCK LLAVKLISVVVVGGAAQQHYATGD---IGALSDDVSLLQFANMIEPANAA
Mvan_0874|M.vanbaalenii_PYR-1 VVAVKLISVVVVGNSAREHFASGD---IGALSDDVSLLRILDVVEPANTA
TH_4401|M.thermoresistible__bu LTAIKLISVVIAGHSAAAHFAAGD---ADGLRRDVATLHLADVIEPQKAR
MSMEG_6606|M.smegmatis_MC2_155 LIIVKLLSVVVAGRSVTSDYAERD---AGAMAGGVSVLRVFNVVEPAKAH
MAB_0658|M.abscessus_ATCC_1997 GFAVKLIVMVSTGYAAQSHYLAYD---SYSLRDDVRILKSWNIIDSYKAY
MUL_4315|M.ulcerans_Agy99 DEAVYPLVTRAGGGSPRDTLSVLDQLVAGAQSNHVTYQRVLGLLGATDVA
MMAR_5451|M.marinum_M PIGGPPPTPEPQQGAPQPHQDIAEEPNPAAAEAPAAPPKSPRPPMPVNGP
: : . . : . .
Mflv_0044|M.gilvum_PYR-GCK VAAGGL--------------------------------------------
Mvan_0874|M.vanbaalenii_PYR-1 SAAGGL--------------------------------------------
TH_4401|M.thermoresistible__bu FAAGTL--------------------------------------------
MSMEG_6606|M.smegmatis_MC2_155 IAEGAR--------------------------------------------
MAB_0658|M.abscessus_ATCC_1997 FTEGDR--------------------------------------------
MUL_4315|M.ulcerans_Agy99 LIDDAVDALGAGDAAALFGAVESVIDAGHDPRRFATDLLERFRDLIVLQA
MMAR_5451|M.marinum_M APTRPEPPLPPGPPRRRAQPPTAPPNQPGQPKPISGHPPPPPRPAAFAPP
Mflv_0044|M.gilvum_PYR-GCK ---AVLHDRLDVADMQFTAALETTDDSRSCPVRINLELVRERRGDIDAWE
Mvan_0874|M.vanbaalenii_PYR-1 ---AVLQDRLEEADAQFADALTRTGADRSCPVRVNLALVREREGDIDAWE
TH_4401|M.thermoresistible__bu ---AVLDGRLADADARFTEVLSGTAAPHSCPVRINLELVRERQGDHAAWA
MSMEG_6606|M.smegmatis_MC2_155 ---AVLEDRLTDAEQQYAQALG---IADTCPVRVDLALVRETLGDRAASR
MAB_0658|M.abscessus_ATCC_1997 ---YVLEGRLAEAETEFKESLKRVDPPESCPVRINLEVVLETRGDLKSAD
MUL_4315|M.ulcerans_Agy99 VPDAVSHGVVDGPEDVLDRMREQAAHLGSATLTRYAEVVQAGLGEMRGAT
MMAR_5451|M.marinum_M ARGATPNRHESAEPPPPRRVRIGGPPQPPGPPEAESEAPRHSRHARRTHR
. . . .
Mflv_0044|M.gilvum_PYR-GCK A------------------------RLDDARQRYEAALTVIADAPPACFA
Mvan_0874|M.vanbaalenii_PYR-1 A------------------------RLEPARQRYESALAVIAEAPQGCFD
TH_4401|M.thermoresistible__bu G------------------------RPDAARERYRSALRIVDEAPPACFA
MSMEG_6606|M.smegmatis_MC2_155 F------------------------ATPAAIAHYEAARDVVARAPQGCFT
MAB_0658|M.abscessus_ATCC_1997 H------------------------KRDDAKKFWEEALAVTREAPAGCFN
MUL_4315|M.ulcerans_Agy99 APRL-----LLEVVCARLLLPSASDAESALLQRIERIETRLAMSIPAGAG
MMAR_5451|M.marinum_M YRPEPETDDLEATAVRPLPTREPMRRNGPAADESSTASFAWLQQSQPTLD
Mflv_0044|M.gilvum_PYR-GCK GNDDPDPQR----RAVR-----ADAAARVQAKIDALG--TVAPLAPPSPP
Mvan_0874|M.vanbaalenii_PYR-1 GNTDPDSAR----RAVR-----EDADERITAKIDALG--SVAPLAPP-PP
TH_4401|M.thermoresistible__bu GNTDPDPER----RXXXXGPGLALGFRRWLAPPVGLGDGDRNPSAPQLVC
MSMEG_6606|M.smegmatis_MC2_155 GNDDPDPQR----RDIR-----EQAQARLDDKLTAMR--TAAPPPPPPPP
MAB_0658|M.abscessus_ATCC_1997 TTSEPDEAV----RKHLN-ETEQRLLDKLKDPPATSASPSPTTSPSPPPP
MUL_4315|M.ulcerans_Agy99 ATSAPAPEAPAAPRATTSARAGAKEMVRQSMRRPAPPEPKSVPEPPPAPE
MMAR_5451|M.marinum_M RPSGPMPAAPGAPVESAPGRADGRRARRRAESRTSAASTPSPLVPTRAQP
* : ..
Mflv_0044|M.gilvum_PYR-GCK PPAAPVAPTAPPPAGADQPRP--DERRLDIGE-DPLA-------------
Mvan_0874|M.vanbaalenii_PYR-1 PVEAPAAPSAPPVAVPDTSDPS-EARRLDRGG-DPRE-------------
TH_4401|M.thermoresistible__bu EETGQDCGTGHFGGRVDEHRCRSDGQRRHRGA-DDRADTVDIVGSGDELN
MSMEG_6606|M.smegmatis_MC2_155 PAAAPVPPPAGAGGTPPDTDT---GDRLNPGTGDPLER------------
MAB_0658|M.abscessus_ATCC_1997 EGGGGNGGDGQGGGNGGDGQGGGNDHNDGQRGGDQNGQPNSLPGEPTQEG
MUL_4315|M.ulcerans_Agy99 PRPAPEPRRAPEPRPAPVPEPVSAPGELNAAAVRSMWPTVREKVRQRSRT
MMAR_5451|M.marinum_M PGPTRAQPPRTAAPAQPATEPLPDAGAPAEQSKKPNKPVPQRGWRRWVYA
Mflv_0044|M.gilvum_PYR-GCK ----ALRQLLR---------------------------DAAG--------
Mvan_0874|M.vanbaalenii_PYR-1 ----ALRQLLR---------------------------DAAAG-------
TH_4401|M.thermoresistible__bu RARGAHRDMLRRDLHHRSRGAGPLGEKFGAAVHLHQLGDGARGVEHPLDP
MSMEG_6606|M.smegmatis_MC2_155 -----LQQILR---------------------------DAAA--------
MAB_0658|M.abscessus_ATCC_1997 PSPGQPTQAPTPVGPDRIPTSGANG----ANELHPDQGDPADVLKRSLEN
MUL_4315|M.ulcerans_Agy99 TEVMLAAATVRALEDNTLVLTHDSAPLARRLSEQRNADVIAEALRDALGV
MMAR_5451|M.marinum_M VTRINFGLSPDEKYELDLRTRIGRKPRGSYQIAILGLKGGAGKTTTTVTL
*
Mflv_0044|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0874|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4401|M.thermoresistible__bu IP------------------------------------------------
MSMEG_6606|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0658|M.abscessus_ATCC_1997 STASGTDTE-----------------------------------------
MUL_4315|M.ulcerans_Agy99 NWRVRCEVGAAEPAATPTPAKAAAPAADPVAVDSARREEEESLLAEAGRS
MMAR_5451|M.marinum_M GTTLTHVRGDRILVLDADPGAGNLAERSGRSSPSSIADLLADPRLSHYND
Mflv_0044|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0874|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4401|M.thermoresistible__bu --------------------------------------------------
MSMEG_6606|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0658|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4315|M.ulcerans_Agy99 DPSEPRRDPEEVALELLRNELGARRIDNA---------------------
MMAR_5451|M.marinum_M VRAHTSVNAANLEILPTAEYTSAQRGLSGEDLRSAVDTVSKFYNLVLADC
Mflv_0044|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0874|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4401|M.thermoresistible__bu --------------------------------------------------
MSMEG_6606|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0658|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4315|M.ulcerans_Agy99 --------------------------------------------------
MMAR_5451|M.marinum_M GAGLFDPVTLGVLDTASAIVILTNVSIDSARQAAIALDWLRKHGYQDLAS
Mflv_0044|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0874|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4401|M.thermoresistible__bu --------------------------------------------------
MSMEG_6606|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0658|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4315|M.ulcerans_Agy99 --------------------------------------------------
MMAR_5451|M.marinum_M RACVAINHVAVGETNVSEQQLVRDFEQQLQPGRVVVLPWDRHIAAGTEIH
Mflv_0044|M.gilvum_PYR-GCK -----------------------------
Mvan_0874|M.vanbaalenii_PYR-1 -----------------------------
TH_4401|M.thermoresistible__bu -----------------------------
MSMEG_6606|M.smegmatis_MC2_155 -----------------------------
MAB_0658|M.abscessus_ATCC_1997 -----------------------------
MUL_4315|M.ulcerans_Agy99 -----------------------------
MMAR_5451|M.marinum_M LDQLGPVYRRRVLELAAALSDDFERAGRR