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VVGAAAVAAGLGISAASLNAGSAYSAPLDPPPPCPNCHGGGGNPGGPGGGPGGQPAGPGGGAGGQHGGNT PPQGGQNNPPQNGPNNAPQNGPNNAPQSGPNNPSQGGPNNAPQNGPNNPPQGGQNEPGGQYPPNQHGQNP PQNGQNQPPYDHDQNPPTPGGPTNAPANTQNPPPPPERQRYAALNPPNTQPPHPPYVPRHDVVTASAQIG GPAGADVQFSIVGRGAPPPPREHGYGWNDGPPPHHPPPNWYGPPPPGGWDGPPPPGGWNRPWDGPPRDVA VARADFGPFSYNTFTVIPVFNWQYGGWGYWFFGVWVPLY
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_0680 | - | - | 100% (319) | hypothetical protein MAV_0680 |
M. avium 104 | MAV_0024 | - | 6e-14 | 31.35% (252) | xyppx repeat-containing protein |
M. avium 104 | MAV_2415 | - | 4e-10 | 26.88% (346) | hypothetical protein MAV_2415 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3906 | - | 7e-10 | 26.21% (248) | hypothetical protein Mb3906 |
M. gilvum PYR-GCK | Mflv_3843 | - | 1e-14 | 30.91% (317) | hypothetical protein Mflv_3843 |
M. tuberculosis H37Rv | Rv3876 | - | 7e-10 | 26.21% (248) | hypothetical protein Rv3876 |
M. leprae Br4923 | MLBr_02395 | Ag36 | 3e-06 | 35.19% (108) | proline rich antigenic protein |
M. abscessus ATCC 19977 | MAB_0803 | - | 3e-13 | 29.83% (238) | hypothetical protein MAB_0803 |
M. marinum M | MMAR_4389 | pra | 5e-13 | 34.34% (166) | proline-rich antigen, Pra |
M. smegmatis MC2 155 | MSMEG_3545 | - | 5e-15 | 33.71% (175) | hypothetical protein MSMEG_3545 |
M. thermoresistible (build 8) | TH_2237 | - | 9e-10 | 34.72% (144) | CONSERVED HYPOTHETICAL PROTEIN TB39.8 |
M. ulcerans Agy99 | MUL_1750 | - | 3e-13 | 33.12% (157) | proline and glycine rich transmembrane protein |
M. vanbaalenii PYR-1 | Mvan_2552 | - | 9e-12 | 28.78% (337) | hypothetical protein Mvan_2552 |
CLUSTAL 2.0.9 multiple sequence alignment MAV_0680|M.avium_104 -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_02395|M.leprae_Br4923 -------------------------------------------------- MMAR_4389|M.marinum_M -------------------------------------------------- Mb3906|M.bovis_AF2122/97 -------------------------------------------------- Rv3876|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK ---MSRTKKSIVVVMMGSAGLFLSAPLLGPAANATPTRGGVPCVGILQQI Mvan_2552|M.vanbaalenii_PYR-1 ---MSRTKKSIVVVMMGSAGLFLSAPLLGPSANATPTRGGVPCVGILQQV MUL_1750|M.ulcerans_Agy99 -------------------------------------------------- MAB_0803|M.abscessus_ATCC_1997 MTDTDRPDGDDAPTQTLPAAAPLSAPELTGFPAGIVGAALTVLGVWGLHV TH_2237|M.thermoresistible__bu -------------------------------------------------- MAV_0680|M.avium_104 ------------------------------------MVGAAAVAAGLGIS MSMEG_3545|M.smegmatis_MC2_155 ------------------------------------MMIVKTTTTRFVAA MLBr_02395|M.leprae_Br4923 -------------------------------------------------- MMAR_4389|M.marinum_M -------------------------------------------------- Mb3906|M.bovis_AF2122/97 --------------------MAADYDKLFRPHEGMEAPDDMAAQPFFDPS Rv3876|M.tuberculosis_H37Rv --------------------MAADYDKLFRPHEGMEAPDDMAAQPFFDPS Mflv_3843|M.gilvum_PYR-GCK VTRPGEIPQALTDTARSFTEPPKPAPPVVRPPASSSSSAGTPPVPGRPPA Mvan_2552|M.vanbaalenii_PYR-1 ISRPGDIPQALTETARSFTNPGQPAPPVVRPPASSSSSVGTPPVPPTPPG MUL_1750|M.ulcerans_Agy99 -----------------------------------------MSQPPENPG MAB_0803|M.abscessus_ATCC_1997 LTRGDGVAGVLGWVILLCLAFSALGKGITLLRRALAPLSAVWSASVDGVP TH_2237|M.thermoresistible__bu MGLADRIERKLEATVGDAFARVFGGSIVPQEVEARLRREAQAGARDVGGG MAV_0680|M.avium_104 AASLNAGSAYSAPLDPPPPCPNCHGGGGNPGGPGGGP-----------GG MSMEG_3545|M.smegmatis_MC2_155 ALTVGALGFGATAFG-------------TPVASAGPA-----------AP MLBr_02395|M.leprae_Br4923 ------------------------------MTDQPPP-----------SG MMAR_4389|M.marinum_M ------------------------------MTDQPPP-----------GG Mb3906|M.bovis_AF2122/97 ASFPPAPASANLPKPNGQTPPPTSDDLSERFVSAPPP-----------PP Rv3876|M.tuberculosis_H37Rv ASFPPAPASANLPKPNGQTPPPTSDDLSERFVSAPPP-----------PP Mflv_3843|M.gilvum_PYR-GCK SVVTPSSGATPPVPPSPGTPASTSTRGGTPPVPPAPPAPAGTPASGATPP Mvan_2552|M.vanbaalenii_PYR-1 SVVRPSSGATPPVPPTPGTPASTTTGVGTPPVPPTPPGSTVRPAAGATPP MUL_1750|M.ulcerans_Agy99 NQADPQDGDQSTPGYPP------------PPNYGTPP-----------PP MAB_0803|M.abscessus_ATCC_1997 PLLRAAAGIIVGAAGIWWVMRGHASGWWAQITGGDSGSGLG-------WS TH_2237|M.thermoresistible__bu RILAPNDYVITLSESDYRKVSADPDRTSTTFAKHLEG--------YIHDQ MAV_0680|M.avium_104 QPAGPGGGAGGQHGGNTPPQGGQNNPPQNGPNNAPQNGPN---------- MSMEG_3545|M.smegmatis_MC2_155 VPLKPGDGGCFPFCDGGPGKPG---------------------------- MLBr_02395|M.leprae_Br4923 SNPTPAPPPPGSSGGYEP----SFAP----SELGSAYPPP---------- MMAR_4389|M.marinum_M SYP-PPPPPPGSSGGSEPPAGGYQAPPPPSAPSGGGYPPP---------- Mb3906|M.bovis_AF2122/97 PPPPPPPPTPMPIAAGEPPSPEPAASKPPTPPMPIAGPEP---------- Rv3876|M.tuberculosis_H37Rv PPPPPPPPTPMPIAAGEPPSPEPAASKPPTPPMPIAGPEP---------- Mflv_3843|M.gilvum_PYR-GCK APPVPGVPAVTSTGGGTPPVPPVPGAPVGAPVANPGLPTPPVPGAPVFGD Mvan_2552|M.vanbaalenii_PYR-1 APPVPGVPAGTPIGGGTPPLPPVPGAPAGTPVANVAPPSPPVPGVPVIGD MUL_1750|M.ulcerans_Agy99 PPPGYGAPPAGPPGYGAPPPPPGYGTPPPPPPPGYGQAPG---------- MAB_0803|M.abscessus_ATCC_1997 LPSQLVQVAIMVVAGALLFGGAKVLGKLIFANSGTRQQPS---------- TH_2237|M.thermoresistible__bu GWQTYGDVVVRFEQSSNLHTGQFRARGLVNPDTTTGEPAQAQ-------- MAV_0680|M.avium_104 ------------NAPQSGPNNPSQGGPNNAPQNGPNNPP----QGGQNEP MSMEG_3545|M.smegmatis_MC2_155 -----------------GPGGPGHGGPG-----GPGGPG----HGGPGGP MLBr_02395|M.leprae_Br4923 ----TAP-------PVGGS--YPPPPPP-----GGSYP--------PPPP MMAR_4389|M.marinum_M ----PPP-------PSPSTSGYPPPPPPPSAPGGSAYP--------PPPP Mb3906|M.bovis_AF2122/97 ----APPKPPTPPMPIAGPEPAPPKPPTPPMPIAGPAPTPTESQLAPPRP Rv3876|M.tuberculosis_H37Rv ----APPKPPTPPMPIAGPEPAPPKPPTPPMPIAGPAPTPTESQLAPPRP Mflv_3843|M.gilvum_PYR-GCK GGAVLPPLPPAPAGPAGGPAGLVAPPAPPVPGGPAAVPAGVALPPAPPGA Mvan_2552|M.vanbaalenii_PYR-1 GGAALPPLPPVPGGPAAVPAGVVTPPAPPIPGGPAAMPAGVAAPPAP-AP MUL_1750|M.ulcerans_Agy99 --------------GYAPPGYNPPPPPPPGYGPPPAGYSTQPGFGGPAKP MAB_0803|M.abscessus_ATCC_1997 --------PNHDGGQRWRQWWASHPGLGLTLLAGGGALVFLSGYVVPRVS TH_2237|M.thermoresistible__bu ------QDRAYTAEPGVPPMSDNPSYRGGQGPGRPADDEYDDRYGRPDDP . MAV_0680|M.avium_104 GGQYPPNQHGQNPPQNGQNQPPYDH------------------------- MSMEG_3545|M.smegmatis_MC2_155 GGHEGPGGPGR--------------------------------------- MLBr_02395|M.leprae_Br4923 P----GGSYPPPP-------PSTGA------------------------- MMAR_4389|M.marinum_M PPPLEGGYPPPPP-------PSAGG------------------------- Mb3906|M.bovis_AF2122/97 PTPQTPTGAPQQPESPAPHVPSHGP------------------------- Rv3876|M.tuberculosis_H37Rv PTPQTPTGAPQQPESPAPHVPSHGP------------------------- Mflv_3843|M.gilvum_PYR-GCK PGAPVFGEAGAAPSGAAAPVAPAAGSGGAGGAGGGSGIGGPGGGGAPVEG Mvan_2552|M.vanbaalenii_PYR-1 PGAPIFGEAGAVPPPGVGGAPLDGASGVAAPGGPGGGAGAPGAPVAAAAG MUL_1750|M.ulcerans_Agy99 PFSVGEAISWAWNRFTQNAMALVVP------------------------- MAB_0803|M.abscessus_ATCC_1997 SWLTGDDPMAALAAITAILALALLAN------------------------ TH_2237|M.thermoresistible__bu RGQYPPADQGGYPPRGGYPEQPGGG------------------------- MAV_0680|M.avium_104 -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_02395|M.leprae_Br4923 -------------------------------------YAP---------- MMAR_4389|M.marinum_M -------------------------------------YAP---------- Mb3906|M.bovis_AF2122/97 -------------------------------------HQPRRTAPAPPWA Rv3876|M.tuberculosis_H37Rv -------------------------------------HQPRRTAPAPPWA Mflv_3843|M.gilvum_PYR-GCK TGGAVPAGAPLAAAGGEVPPPAPPIPGAPVIGEAGVVPPPAPPAPAPPAG Mvan_2552|M.vanbaalenii_PYR-1 NAGPPAPGAPVGDQAGVVAPPAPPAPGAPVGDQAGLVAPPGPPAPGVPVV MUL_1750|M.ulcerans_Agy99 -------------------------------------------------I MAB_0803|M.abscessus_ATCC_1997 -----------------------------------------TWWWRALSG TH_2237|M.thermoresistible__bu -------------------------------------------------- MAV_0680|M.avium_104 ----DQNPPTPGGPTN---------APANTQNPPPPPERQRYAALNPPNT MSMEG_3545|M.smegmatis_MC2_155 -----HDGPGPGGPG----------GPGRHDGP----------------- MLBr_02395|M.leprae_Br4923 ------PPPGPAIR----------SLPKEAYTFWVTRVLAYVIDNIPATV MMAR_4389|M.marinum_M ------PPPGPAIR----------ALPAESYTPWITRVLAALIDFAPYVV Mb3906|M.bovis_AF2122/97 KMPIGEPPPAPSRPSASPAEPP--TRPAPQHSRRARRGHRYRTDTERNVG Rv3876|M.tuberculosis_H37Rv KMPIGEPPPAPSRPSASPAEPP--TRPAPQHSRRARRGHRYRTDTERNVG Mflv_3843|M.gilvum_PYR-GCK GLGGAVPPPVPGAPGVPVVDEAGVVTPPAPGGPGVPTGGEGGVVTPPAPG Mvan_2552|M.vanbaalenii_PYR-1 DQAGVVAPPGPPAPGVPVVDEAGVVTPPGPGAPGVPVVGEAGVVTPPGPG MUL_1750|M.ulcerans_Agy99 VIYGLILSAVGGVMVGLFFAFSDRTSTTYTDAYGNTSETVNMTMSPLASI MAB_0803|M.abscessus_ATCC_1997 WWAWAHTPNGPGGP-----------TPIGQIYAGAGVLALIAFSATAFGL TH_2237|M.thermoresistible__bu -----YPEQQGGYPEQQGGYPDQGGYPPRGGYPDQGGYPEQGGYPDQGGY . MAV_0680|M.avium_104 QPPHPPYVPRHDVVTASA-------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_02395|M.leprae_Br4923 LLGIGMLIQTLTKQEACV-------------------------------- MMAR_4389|M.marinum_M VTGIGWLIMMVTTTSSCV-------------------------------- Mb3906|M.bovis_AF2122/97 KVATGPSIQARLRAEEASGAQLAPGTEPSPAPLGQPRSYLAPPTRPAPTE Rv3876|M.tuberculosis_H37Rv KVATGPSIQARLRAEEASGAQLAPGTEPSPAPLGQPRSYLAPPTRPAPTE Mflv_3843|M.gilvum_PYR-GCK APGVPVVDEAGVVTPPAPGGPGVPTGGEGGVVTPPAPGAPGAPVVDEAGV Mvan_2552|M.vanbaalenii_PYR-1 APGVPVVDEAGVVTPPGPGAPGVPVVDEAGVVTPPGPGAPGVPVVDEAGV MUL_1750|M.ulcerans_Agy99 VMFIGYLAVFAVVLFMHAG------------------------------- MAB_0803|M.abscessus_ATCC_1997 ATFSSYLPQNAATASADPCGDRCGGGGNGQGSYGPDTGNFQPPQMPGQQP TH_2237|M.thermoresistible__bu PPSYEQRPPAGYGPPPGGG------------------------------- MAV_0680|M.avium_104 -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_02395|M.leprae_Br4923 -------------------------------------------------- MMAR_4389|M.marinum_M -------------------------------------------------- Mb3906|M.bovis_AF2122/97 PPPSPSPQRNSGRRAERRVHPDLAAQHAAAQPDSITAATTGGRRRKRAAP Rv3876|M.tuberculosis_H37Rv PPPSPSPQRNSGRRAERRVHPDLAAQHAAAQPDSITAATTGGRRRKRAAP Mflv_3843|M.gilvum_PYR-GCK VTPPAPGGPGVPAVGDTAVVTPPAPGAPGTPAVNSVETFSPPAPPAATPP Mvan_2552|M.vanbaalenii_PYR-1 VTPPAPGAPGVPVDGGAELVTPPGPGAPGTPTVSSVETFSPPAPPAPGTP MUL_1750|M.ulcerans_Agy99 -------------------------------------------------- MAB_0803|M.abscessus_ATCC_1997 DYQGGINQPPLDQNSGISIYNESPGQGGQQIPQQNMGPQTSGQRAAHGEP TH_2237|M.thermoresistible__bu -------------------------------------------------- MAV_0680|M.avium_104 ----------QIGGPAGADVQFSIVGRGAPPPPREHGYGWNDGPPPHHPP MSMEG_3545|M.smegmatis_MC2_155 ------------GGPGGPGWHDPGHGPDKGPWWANNRHDWWDDR--QGPP MLBr_02395|M.leprae_Br4923 ---------------TDITQYNVNQYCATQPTGIGMLAFWFAWLMATAYL MMAR_4389|M.marinum_M ---------------TDISQYDIGQYCVSQPSMIGQLAQWLLSLVGLAYL Mb3906|M.bovis_AF2122/97 DLDATQKSLRPAAKGPKVKKVKPQKPKATKPPKVVSQRGWRHWVHALTRI Rv3876|M.tuberculosis_H37Rv DLDATQKSLRPAAKGPKVKKVKPQKPKATKPPKVVSQRGWRHWVHALTRI Mflv_3843|M.gilvum_PYR-GCK SSGSVETFSPPAPPAPGTGTNSTVEISTPPPPGTPGLPSEGSTTYTTPPT Mvan_2552|M.vanbaalenii_PYR-1 SSGSIETFSPPAPPTPGTPANSSVEIVTPPPPGVPGVPGEGSTTYTTPPT MUL_1750|M.ulcerans_Agy99 -------ITTGCLDIADGKPVTIGSFFKPRNLGMVILTGLLVIVLTAIGS MAB_0803|M.abscessus_ATCC_1997 LPNYGPWQPDAQPPAQAPVQQAPVQQAPQAPQQPAQAPQNPAGQQPAQQA TH_2237|M.thermoresistible__bu ------------YDQGYRQPPPGYGPPGGQPGYGAPPAGEYDYGRPPGGR MAV_0680|M.avium_104 PNWYGPP----------PPGGWDG-------------------PPPPGGW MSMEG_3545|M.smegmatis_MC2_155 PWGWGPP----------PPVHWNG-------------------GPLPHTI MLBr_02395|M.leprae_Br4923 VWNYG------------YRQGATG-------------------SSIGKTV MMAR_4389|M.marinum_M VWDYG------------YRQGTTG-------------------SSIGKSI Mb3906|M.bovis_AF2122/97 NLGLSPDEKYELDLHARVRRNPRGSYQIAVVGLKGGAGKTTLTAALGSTL Rv3876|M.tuberculosis_H37Rv NLGLSPDEKYELDLHARVRRNPRGSYQIAVVGLKGGAGKTTLTAALGSTL Mflv_3843|M.gilvum_PYR-GCK PEITLNPANSGIDIATPPAPGLPGAPLEATANITTPGTPGVPGAPVNSSI Mvan_2552|M.vanbaalenii_PYR-1 PEITLNPANSSIDVATPPGPGVPGVPVEASANVSTPPVPGVPGAPVNSSV MUL_1750|M.ulcerans_Agy99 VLCIVPG----------LIFGFLAQ--------------FAIIAAVDRSL MAB_0803|M.abscessus_ATCC_1997 PQQPAGQQPAQQNPPQQGQPGQQQPQNPVNQQTPQQQPQKEPDTPKKNPM TH_2237|M.thermoresistible__bu PDDYGRPGHPDQGGYPDQGGGYPDQ----------------GYGDQGGGY MAV_0680|M.avium_104 NRPWDGPP-----------------------RDVAVARADFGPFSYNTFT MSMEG_3545|M.smegmatis_MC2_155 N--------------------------------------------YWGYN MLBr_02395|M.leprae_Br4923 MKFKV------------------------------ISEATGQPIGFGMS- MMAR_4389|M.marinum_M MKFKV------------------------------VSETTGEPLGFGMS- Mb3906|M.bovis_AF2122/97 AQVRADRI----------------LALDADPGAGNLADRVGRQSGATIAD Rv3876|M.tuberculosis_H37Rv AQVRADRI----------------LALDADPGAGNLADRVGRQSGATIAD Mflv_3843|M.gilvum_PYR-GCK DVATPGEVGVPAAPIERSMTVTTPDTPGAPGAPANAAVDVATPPAPGVPG Mvan_2552|M.vanbaalenii_PYR-1 EVATPAEVGVPGTPIERSTTLTTPPTPGVPGTPVNSSVEVATPPAPGAPG MUL_1750|M.ulcerans_Agy99 SPIDS-----------------------------IKSSCATVRAELGNTA MAB_0803|M.abscessus_ATCC_1997 DPTDLATAATR---------------RGSQQAGQQAAQQAGQQGAQQAAQ TH_2237|M.thermoresistible__bu PDQGYGDQ-------------------------GYGGQPYGRPDYGQQPG MAV_0680|M.avium_104 VIPVFNWQYGGWG------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 LNPVWHDGFRQWG------------------------------------- MLBr_02395|M.leprae_Br4923 --VVRQLAHFVDA------------------------------------- MMAR_4389|M.marinum_M --VVRQLAHIVDA------------------------------------- Mb3906|M.bovis_AF2122/97 VLAEKELSHYNDIRAHTSVNAVNLEVLPAPEYSSAQRALSDADWHFIADP Rv3876|M.tuberculosis_H37Rv VLAEKELSHYNDIRAHTSVNAVNLEVLPAPEYSSAQRALSDADWHFIADP Mflv_3843|M.gilvum_PYR-GCK APVVGEAGVTTPGAPGAPGAPANAAVDVATPPAPGVPGAPVVGEAAVTTP Mvan_2552|M.vanbaalenii_PYR-1 VPVVDEAGVVTPPGPGAPGVPVVGEAGVVTPPGPGAPGVPVVDEAGVVTP MUL_1750|M.ulcerans_Agy99 LSWLVQYAVVLAG------------------------------------- MAB_0803|M.abscessus_ATCC_1997 QTTQGTQQATQQG----------------------------------TQK TH_2237|M.thermoresistible__bu QGDYGAGGYGDAG------------------------------------- MAV_0680|M.avium_104 ----------YWFFGVWVP---------LY-------------------- MSMEG_3545|M.smegmatis_MC2_155 ----------VWLFGIWIP---------IFGVGFN--------------- MLBr_02395|M.leprae_Br4923 ---------VICCIGFLFP---------LWDSKRQTLA------------ MMAR_4389|M.marinum_M ---------IICYIGFLFP---------LWDAKRQTLA------------ Mb3906|M.bovis_AF2122/97 ASRFYNLVLADCGAGFFDP---------LTRGVLSTVSGVVVVASVSIDG Rv3876|M.tuberculosis_H37Rv ASRFYNLVLADCGAGFFDP---------LTRGVLSTVSGVVVVASVSIDG Mflv_3843|M.gilvum_PYR-GCK GAPGVPGVPAGGDAGVVTPPAPGVPGAPVVGEAGVTTPGAPGVPGVPAGG Mvan_2552|M.vanbaalenii_PYR-1 PGPGAPGVPVVGEAGVVTPPGPGAPGVPVVDEAGVVTPPGPGAPGVPVVG MUL_1750|M.ulcerans_Agy99 --------ELLCFVGMLVG--------VPVASLIQTYT------------ MAB_0803|M.abscessus_ATCC_1997 PVESGEQFPADFHMGQLGDG---LSKTGKYANTGTHWAPDAKVSTMSKST TH_2237|M.thermoresistible__bu ----------GYGAGYGDPG---------RGDYDYAGAGYGQDAGYGRQD * MAV_0680|M.avium_104 -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_02395|M.leprae_Br4923 ----------------DKIMTTVCLPI----------------------- MMAR_4389|M.marinum_M ----------------DKIMTTVCLPL----------------------- Mb3906|M.bovis_AF2122/97 AQQASVALDWLRNNGYQDLASRACVVINHIMPGEPNVAVKDLVRHFEQQV Rv3876|M.tuberculosis_H37Rv AQQASVALDWLRNNGYQDLASRACVVINHIMPGEPNVAVKDLVRHFEQQV Mflv_3843|M.gilvum_PYR-GCK DAGVVTPPAPGVPGAPAATEAGLATPPGPGAPGAPVVGDAGVATPPGPGV Mvan_2552|M.vanbaalenii_PYR-1 EAGVVTPPGPGAPGVPVVDEAGVVTPPGPGAPGVPVVDEAGVVTPPGPGA MUL_1750|M.ulcerans_Agy99 ---------------WRKLSGGQVVELSQPGPPAGLPPGPPPGAPPGPQF MAB_0803|M.abscessus_ATCC_1997 AQNLLRAGEKFTWLGRGMEVAKAGVDLANGAPVPETVGSTVGSLAGAWAG TH_2237|M.thermoresistible__bu YQQPPATGRPTTVTLQLDDGSGRTYQLREGANVIGRGQDAQFRLPDTGVS MAV_0680|M.avium_104 -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_02395|M.leprae_Br4923 -------------------------------------------------- MMAR_4389|M.marinum_M -------------------------------------------------- Mb3906|M.bovis_AF2122/97 QPGRVVVMPWDRHIAAGTEISLDLLDPIYKRKVLELAAALSDDFERAGRR Rv3876|M.tuberculosis_H37Rv QPGRVVVMPWDRHIAAGTEISLDLLDPIYKRKVLELAAALSDDFERAGRR Mflv_3843|M.gilvum_PYR-GCK PGAPIVDEAGLATPPAP-----VAPVEGAGGAVPPAGPPPAPVFGDAGAP Mvan_2552|M.vanbaalenii_PYR-1 PGVPVVDEAGVVTPPAPPAAAPGAPIDAAAASVAPSGPPAAPVLGEAGVV MUL_1750|M.ulcerans_Agy99 G------------------------------------------------- MAB_0803|M.abscessus_ATCC_1997 AEGGAIIGASIGSFFPGPGTVIGGAVGGVIGGFVGSGLGSEVGKAAGGAV TH_2237|M.thermoresistible__bu RRHLEIRWDGQVALLSDLNSTNGTTVNNAPVQEWQLADGDVIRLGHSEII MAV_0680|M.avium_104 -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_02395|M.leprae_Br4923 -------------------------------------------------- MMAR_4389|M.marinum_M -------------------------------------------------- Mb3906|M.bovis_AF2122/97 -------------------------------------------------- Rv3876|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK VEAAAGGAPVEAAAGVTGGGSVAGAGAGGGAGGAAGGAGVEGASGAVGAA Mvan_2552|M.vanbaalenii_PYR-1 APPAP-----------PGGGAPGGGAPGAGVG---TGAPIEGAAGAGGVP MUL_1750|M.ulcerans_Agy99 -------------------------------------------------- MAB_0803|M.abscessus_ATCC_1997 RAAGSALSKAGGAVASFFGSL----------------------------- TH_2237|M.thermoresistible__bu VRMH---------------------------------------------- MAV_0680|M.avium_104 -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_02395|M.leprae_Br4923 -------------------------------------------------- MMAR_4389|M.marinum_M -------------------------------------------------- Mb3906|M.bovis_AF2122/97 -------------------------------------------------- Rv3876|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK GGPGAGAAPAAAGGAAPGGAPGGPVAGGGPVGGPGALPAPGAPIVGEAGV Mvan_2552|M.vanbaalenii_PYR-1 AAPLAANAGAAT---PPAAATGG----------------AGAPIDAAAGA MUL_1750|M.ulcerans_Agy99 -------------------------------------------------- MAB_0803|M.abscessus_ATCC_1997 -------------------------------------------------- TH_2237|M.thermoresistible__bu -------------------------------------------------- MAV_0680|M.avium_104 -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_02395|M.leprae_Br4923 -------------------------------------------------- MMAR_4389|M.marinum_M -------------------------------------------------- Mb3906|M.bovis_AF2122/97 -------------------------------------------------- Rv3876|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK VSPPAPGVPGGAAAVPAGAVTPPAPGVPGAPVFGEAGVVTPPAPGVPGGA Mvan_2552|M.vanbaalenii_PYR-1 AAPPAP----------------PAP---GAPIFGEAGVAAPPLPPAPGGA MUL_1750|M.ulcerans_Agy99 -------------------------------------------------- MAB_0803|M.abscessus_ATCC_1997 -------------------------------------------------- TH_2237|M.thermoresistible__bu -------------------------------------------------- MAV_0680|M.avium_104 -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_02395|M.leprae_Br4923 -------------------------------------------------- MMAR_4389|M.marinum_M -------------------------------------------------- Mb3906|M.bovis_AF2122/97 -------------------------------------------------- Rv3876|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK AAVPAGVVTPPAPGVPGGAAAVPAGAVTPPAPGVPGAPVFGDAGVATPPV Mvan_2552|M.vanbaalenii_PYR-1 GAVPAGVVTPPVPGVPGGAGAVPAGAVTPPTP----------------PV MUL_1750|M.ulcerans_Agy99 -------------------------------------------------- MAB_0803|M.abscessus_ATCC_1997 -------------------------------------------------- TH_2237|M.thermoresistible__bu -------------------------------------------------- MAV_0680|M.avium_104 -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_02395|M.leprae_Br4923 -------------------------------------------------- MMAR_4389|M.marinum_M -------------------------------------------------- Mb3906|M.bovis_AF2122/97 -------------------------------------------------- Rv3876|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK PGVPGGGTTVPAASVTPPAPGVPGGASTVPGNAGTPSTPGLPPGSTDTYI Mvan_2552|M.vanbaalenii_PYR-1 PGSSSGG-----------------------------------------FV MUL_1750|M.ulcerans_Agy99 -------------------------------------------------- MAB_0803|M.abscessus_ATCC_1997 -------------------------------------------------- TH_2237|M.thermoresistible__bu -------------------------------------------------- MAV_0680|M.avium_104 -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_02395|M.leprae_Br4923 -------------------------------------------------- MMAR_4389|M.marinum_M -------------------------------------------------- Mb3906|M.bovis_AF2122/97 -------------------------------------------------- Rv3876|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK NYPAPPVPPTPPNSTGVSAGTPGSPAPGTPGSTLTLTDLLTPPGIARTLQ Mvan_2552|M.vanbaalenii_PYR-1 NYPAPPVPPTPPNSAGVNTGTPGSPIPGTPGSTLTISDLLTPPGVARTVQ MUL_1750|M.ulcerans_Agy99 -------------------------------------------------- MAB_0803|M.abscessus_ATCC_1997 -------------------------------------------------- TH_2237|M.thermoresistible__bu -------------------------------------------------- MAV_0680|M.avium_104 -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_02395|M.leprae_Br4923 -------------------------------------------------- MMAR_4389|M.marinum_M -------------------------------------------------- Mb3906|M.bovis_AF2122/97 -------------------------------------------------- Rv3876|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK NTASSVMGATPPGTPPVPGGSGSVSLAVPGTPSPIAPLAATGLSNLVSPP Mvan_2552|M.vanbaalenii_PYR-1 NTASSVMSIAPPGTPPVPGGAGSVSVGVPAPPSPLTPLAATGLSNLVSPP MUL_1750|M.ulcerans_Agy99 -------------------------------------------------- MAB_0803|M.abscessus_ATCC_1997 -------------------------------------------------- TH_2237|M.thermoresistible__bu -------------------------------------------------- MAV_0680|M.avium_104 -------------------------------------------------- MSMEG_3545|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_02395|M.leprae_Br4923 -------------------------------------------------- MMAR_4389|M.marinum_M -------------------------------------------------- Mb3906|M.bovis_AF2122/97 -------------------------------------------------- Rv3876|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK SLTIPSIPGLPVPLPNTVPVPSDLLCVGTDWSASQGDSAATPPAAEVPR- Mvan_2552|M.vanbaalenii_PYR-1 SLTIPSIPGLPVPLPNEVPVPSDLLCVGTDWSATQGDSATTPVNAEIPRA MUL_1750|M.ulcerans_Agy99 -------------------------------------------------- MAB_0803|M.abscessus_ATCC_1997 -------------------------------------------------- TH_2237|M.thermoresistible__bu -------------------------------------------------- MAV_0680|M.avium_104 ------------------ MSMEG_3545|M.smegmatis_MC2_155 ------------------ MLBr_02395|M.leprae_Br4923 ------------------ MMAR_4389|M.marinum_M ------------------ Mb3906|M.bovis_AF2122/97 ------------------ Rv3876|M.tuberculosis_H37Rv ------------------ Mflv_3843|M.gilvum_PYR-GCK VVTGAAPTGDRRDRWGNR Mvan_2552|M.vanbaalenii_PYR-1 LVTGAAPVGDRRDRWDTR MUL_1750|M.ulcerans_Agy99 ------------------ MAB_0803|M.abscessus_ATCC_1997 ------------------ TH_2237|M.thermoresistible__bu ------------------