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VILSTPARAVRSSSWIEPDPAGRHKQAGSGSAVARTQRITLTGRAHTYTVLGQDHLPIAPVTEYLQFLRD DQASPNTLRAYAAGLAAWWNLLEETNTGWTDVTTALFGEFLTYLRTGDLPGTSRIGPPAVWLSAASVQQR AAAVLSFYRYHAHAHNLDAPYQRLYGTLGKPGRARYIPLLAGVGRPVRKPRPIYRVRGGNTSRTPVLLPE QVRTILDLCAVQDRSGQWSGSPAALRDRLLFALLAETGMRMGEALTLRHHDVHIGAGGTPWVEVVPRQDH PAGVRVKGGHRRIYVGDDLEALYSAYVWHLVDTGAHEHVPDLDTHFVFVNLAGGQLYAPTRPETVYAKVR SISHNAKGAVPKDWSPHWMRHTHATALLLSGVPPHVVMRRLGHQDIQTTLSTYGWVTEDAEMRSVAEWRN FVAGWKGLHDDPH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0442 | - | - | 100% (433) | putative transposase/integrase |
| M. abscessus ATCC 19977 | MAB_4875c | - | e-178 | 72.89% (402) | putative transposase/phage integrase |
| M. abscessus ATCC 19977 | MAB_2366 | xerD | 3e-09 | 27.47% (375) | site-specific tyrosine recombinase XerD |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1727 | xerD | 3e-10 | 27.59% (377) | site-specific tyrosine recombinase XerD |
| M. gilvum PYR-GCK | Mflv_4645 | - | 2e-15 | 28.00% (350) | phage integrase family protein |
| M. tuberculosis H37Rv | Rv1701 | xerD | 3e-10 | 27.59% (377) | site-specific tyrosine recombinase XerD |
| M. leprae Br4923 | MLBr_01365 | xerD | 1e-10 | 25.94% (374) | site-specific tyrosine recombinase XerD |
| M. marinum M | MMAR_1433 | - | 5e-14 | 25.65% (347) | site-specific integrase |
| M. avium 104 | MAV_0505 | - | 1e-149 | 64.34% (401) | putative transposase |
| M. smegmatis MC2 155 | MSMEG_4155 | - | 3e-38 | 33.33% (378) | transposase A |
| M. thermoresistible (build 8) | TH_3114 | - | 1e-167 | 70.00% (400) | PUTATIVE phage integrase family protein |
| M. ulcerans Agy99 | MUL_1690 | xerD | 1e-10 | 27.76% (371) | site-specific tyrosine recombinase XerD |
| M. vanbaalenii PYR-1 | Mvan_5418 | - | 1e-162 | 69.42% (399) | phage integrase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
TH_3114|M.thermoresistible__bu --------------------------------MARTQRIALTDRPDTYTV
Mvan_5418|M.vanbaalenii_PYR-1 --------------------------------MARTQRIALAEDTDTFTV
MAB_0442|M.abscessus_ATCC_1997 MILSTPARAVRSSSWIEPDPAGRHKQAGSGSAVARTQRITLTGRAHTYTV
MAV_0505|M.avium_104 -------------------------------MVARSQRVSFGEGPDTYTV
MSMEG_4155|M.smegmatis_MC2_155 --------------------------------------------------
Mb1727|M.bovis_AF2122/97 --------------------------------------------------
Rv1701|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1690|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01365|M.leprae_Br4923 --------------------------------------------------
Mflv_4645|M.gilvum_PYR-GCK -------------------------------MTIQHQLRLQAGTDVAWVL
MMAR_1433|M.marinum_M ---------------------------------MTKELAAVVDDDGVWQL
TH_3114|M.thermoresistible__bu LGADHLPVDPAEEYLQFLRDDAASPNTVKAYAAGLAAWWTLLEYT-GTDW
Mvan_5418|M.vanbaalenii_PYR-1 VGPDFLPIDPAEEFLQFLRDDEASPNTVKAYAAGLAAWWTVLEHT-GTDW
MAB_0442|M.abscessus_ATCC_1997 LGQDHLPIAPVTEYLQFLRDDQASPNTLRAYAAGLAAWWNLLEET-NTGW
MAV_0505|M.avium_104 VGDDGLPIGPAAEYLRFLRDGGASPHTVRAYAAGIADWFTVLSHT-GHVW
MSMEG_4155|M.smegmatis_MC2_155 -----MPVAPVERYLKYLTDIERSPNTIKAYAHDLKDWFTFLGGR-GLDW
Mb1727|M.bovis_AF2122/97 MKTLAL--QLQGYLDHLTIERGVAANTLSSYRRDLRRYSKHLEERGITDL
Rv1701|M.tuberculosis_H37Rv MKTLAL--QLQGYLDHLTIERGVAANTLSSYRRDLRRYSKHLEERGITDL
MUL_1690|M.ulcerans_Agy99 MSTLTLDTQLQGYLDHLAIERGVAANTLSSYRRDLRRYSKHLEDRGITDL
MLBr_01365|M.leprae_Br4923 MTTAALQTQLQGYLDYLIIERSIAANTLSSYRRDLIRYSKHLSDRGIEDL
Mflv_4645|M.gilvum_PYR-GCK SGPGCGKYALVNEYLRYLADRNYSPRTLRAYGYDLLAFCRWLGSV-DVEL
MMAR_1433|M.marinum_M RGTAAEQFGLVNEFLGYLADRNFSPRTCRAYAYDLLAFARWLRDE-QLGV
: :..* :* .: : *
TH_3114|M.thermoresistible__bu REVSTAMFGQFLAYLRS---GDLP--GTARIGAPPTWLGPASTQLRAAAV
Mvan_5418|M.vanbaalenii_PYR-1 REISTSLFGQFLAYLRT---GDLP--GTARIGAPEGWLGAASTALRAAAV
MAB_0442|M.abscessus_ATCC_1997 TDVTTALFGEFLTYLRT---GDLP--GTSRIGPPAVWLSAASVQQRAAAV
MAV_0505|M.avium_104 DDFPTTLFGQYLQFLRT---GDLP--GSARIGPPQQRLAASSLQPRAAAV
MSMEG_4155|M.smegmatis_MC2_155 QSVSLEDIGAFVVWLRL---PTALRQGGIAVLPSVEHHCGESTVNRKLSA
Mb1727|M.bovis_AF2122/97 AKVGEHDVSEFLVALRR----GDPDSGTAALS--------AVSAARALIA
Rv1701|M.tuberculosis_H37Rv AKVGEHDVSEFLVALRR----GDPDSGTAALS--------AVSAARALIA
MUL_1690|M.ulcerans_Agy99 AKVGEDDVSEFLVALRR----GDPESGVLGLS--------AVSAARALIA
MLBr_01365|M.leprae_Br4923 AKVGEHDVSEFLVALRR----GDPDSGVAALS--------AVSAARALIA
Mflv_4645|M.gilvum_PYR-GCK SSVTTETVLDFMRHCRQTPIAGRP-TNVVSMTGTRLDRYSSTTINHRLAA
MMAR_1433|M.marinum_M AEVNVDVLLRFLTACREATLPGRPGGNVYSIRDGRNQGYAPATINRRLAA
.. . :: * . : : .
TH_3114|M.thermoresistible__bu LACYRYHADAHGLPVPYRRLFTSRGKRGRSR-YIPMLAGVGPPR-TKDRP
Mvan_5418|M.vanbaalenii_PYR-1 LACYRYHADAHGLVGPYQRLHTSRGKRGRSR-YIPMLAGVGAARPAKDRP
MAB_0442|M.abscessus_ATCC_1997 LSFYRYHAHAHNLDAPYQRLYGTLGKPGRAR-YIPLLAGVGRPV-RKPRP
MAV_0505|M.avium_104 LSMYRYHADAHHVDTPYRRLFTSRGSWRRYRRYVGFLDGVGPQR-RGDHP
MSMEG_4155|M.smegmatis_MC2_155 LAAFYLHAVRDGIDVG--ELLTTWQIGGSRGGWKPFLHHISKHMPSPRRT
Mb1727|M.bovis_AF2122/97 VRGLHRFAAAEG---LAELDVAR----------------AVRPPTPSRR-
Rv1701|M.tuberculosis_H37Rv VRGLHRFAAAEG---LAELDVAR----------------AVRPPTPSRR-
MUL_1690|M.ulcerans_Agy99 VRGLHRFAAAEG---LAALDVAR----------------AVRPPTPGRR-
MLBr_01365|M.leprae_Br4923 VRGLHRFAVAEG---LVDLDVAR----------------AVRPPTPGRR-
Mflv_4645|M.gilvum_PYR-GCK LTGLFTFRELRDPGLRTPIPSGR----------------EARRVSAEERN
MMAR_1433|M.marinum_M ISSLFAFREMRDPDARSLVGSSR----------------AARLRSRGERS
: . :
TH_3114|M.thermoresistible__bu VYTVRRGNLAATPVLLPSQVAAILDGCATQN-GHVWSGPASGLRDRLLFA
Mvan_5418|M.vanbaalenii_PYR-1 IYTVRRGNRAATPVLLPAQVGLILDGCATQT-GHEWSGPASGLRDRLLFA
MAB_0442|M.abscessus_ATCC_1997 IYRVRGGNTSRTPVLLPEQVRTILDLCAVQDRSGQWSGSPAALRDRLLFA
MAV_0505|M.avium_104 IYRMRTQNRCTTPVLTPPQVNTILDACSVQH-DGTWSGGPAAVRNRLLFA
MSMEG_4155|M.smegmatis_MC2_155 VS--LKAPKKLPRVLTPGEVQTLLDACDRLR-------------DRFLLA
Mb1727|M.bovis_AF2122/97 -------LPKS---LTIDEVLSLLEGAGGDK-PSDGP---LTLRNRAVLE
Rv1701|M.tuberculosis_H37Rv -------LPKS---LTIDEVLSLLEGAGGDK-PSDGP---LTLRNRAVLE
MUL_1690|M.ulcerans_Agy99 -------LPKS---LTIDEVLALLEGAGGDN-PADGP---LTLRNRALLE
MLBr_01365|M.leprae_Br4923 -------LPKS---LTVDEVLALLESVGGES-RADGP---LVLRNRALLE
Mflv_4645|M.gilvum_PYR-GCK GLLGHLVRPKRRSALRLREPRRLPRALNRRE-TAELLSSLRTWRDRALAG
MMAR_1433|M.marinum_M GLLAHTAKPKSRSQLRVREPRWLPRGLSREE-SAALLGSFRSWRDRAIGG
* : : :* :
TH_3114|M.thermoresistible__bu TLAETGMRLGEALSLRHHDFHLGTGATPYIEVGTRQDHPRGARGKTLHGR
Mvan_5418|M.vanbaalenii_PYR-1 VLAETGMRLGEALSLRHHDFHIGAGGTPWIDIAARQDHPRGARGKTLSPR
MAB_0442|M.abscessus_ATCC_1997 LLAETGMRMGEALTLRHHDVHIGAGGTPWVEVVPRQDHPAGVRVKGGH-R
MAV_0505|M.avium_104 VLAETGMRLGEALSLRHHDFHIGAGATPFIEIVDRQDHPHGVRVKTGS-R
MSMEG_4155|M.smegmatis_MC2_155 LLYDAGMRIGEALGLRHSDIAAAER----QVTVCRRDNDNRARAKSLTAR
Mb1727|M.bovis_AF2122/97 LLYSTGARISEAVGLDLDDIDTHAR-------------SVLLRGKGGKQR
Rv1701|M.tuberculosis_H37Rv LLYSTGARISEAVGLDLDDIDTHAR-------------SVLLRGKGGKQR
MUL_1690|M.ulcerans_Agy99 LLYSTGSRISEAVGLDVDDIDTQAR-------------TVLLQGKGGKQR
MLBr_01365|M.leprae_Br4923 LLYSTGSRISEAVGLDVDDVDTQAR-------------TVLLQGKGGKQR
Mflv_4645|M.gilvum_PYR-GCK LMLLSGLRSGELLTLDVTDVDIGAR-------------WVKVMGKGAKER
MMAR_1433|M.marinum_M LMLLSGLRSAEVLGLRVSDIDIARR-------------WVRVLGKGGKER
: :* * .* : * *. * *
TH_3114|M.thermoresistible__bu RIYIGDDLEALYSSYVWHLVDHGADLAMPNLDTHFVFVNLVAGERFAPMR
Mvan_5418|M.vanbaalenii_PYR-1 RVYIGDDLEALYSSYVWHLIDHGADLAVPDLTTHFVFVNLTAGTPFAPTR
MAB_0442|M.abscessus_ATCC_1997 RIYVGDDLEALYSAYVWHLVDTGAHEHVPDLDTHFVFVNLAGGQLYAPTR
MAV_0505|M.avium_104 RVYVGDDLEALYSEYVWQLVAMAADVEVPDLASHFVFVNLAHGPRFAAMR
MSMEG_4155|M.smegmatis_MC2_155 IVPVSAELIRLYADYLHAEYG--------DLDSDYVFVNLWGRPHGHPLT
Mb1727|M.bovis_AF2122/97 LVPVGRPAVHALDAYLVRGRPDLARRGRG---TAAIFLNARGGR----LS
Rv1701|M.tuberculosis_H37Rv LVPVGRPAVHALDAYLVRGRPDLARRGRG---TAAIFLNARGGR----LS
MUL_1690|M.ulcerans_Agy99 LVPVGRPAVQALDAYLVRGRPELARRGRG---TPAIFLNARGGR----LS
MLBr_01365|M.leprae_Br4923 LVPVGRPAVQALDAYLVRGRSDLARRGPGMLATPAIFLNARGGR----LS
Mflv_4645|M.gilvum_PYR-GCK RVPLDVEVAGLIQTYLLVERPESD--------SNRLFLVAKGPHRGQPLT
MMAR_1433|M.marinum_M SVPIDTDVAGAIQTYLLAERPETD--------ADELFVVAKGAHRGRPLT
: :. *: : :*:
TH_3114|M.thermoresistible__bu AETVYAKVDSLTRRSNGVLPEDWTPHWLRHTHATALLLSGAPPHVVMRRL
Mvan_5418|M.vanbaalenii_PYR-1 PETVYAKVDSVTSRAAGALPQGWSPHWLRHTHATALLLSGAAPHVVMRRL
MAB_0442|M.abscessus_ATCC_1997 PETVYAKVRSISHNAKGAVPKDWSPHWMRHTHATALLLSGVPPHVVMRRL
MAV_0505|M.avium_104 VETVYDKVRGIKR-AQPSLPAGWTPHWLRHTHATALLLAGVPEHVVMRRL
MSMEG_4155|M.smegmatis_MC2_155 YGAVYDLVRRLRR----RTAIDFDPHWLRHTAATRMLRDGIGLEVVAKLL
Mb1727|M.bovis_AF2122/97 RQSAWQVLQDAAE--RAGITAGVSPHMLRHSFATHLLEGGADVRVVQELL
Rv1701|M.tuberculosis_H37Rv RQSAWQVLQDAAE--RAGITAGVSPHMLRHSFATHLLEGGADVRVVQELL
MUL_1690|M.ulcerans_Agy99 RQSAWQVLQDAAE--RADITSGVSPHMLRHSFATHLLEGGADVRVVQELL
MLBr_01365|M.leprae_Br4923 RQSAWQVLQDAAE--HAGITSGVSPHMLRHSFATHLLEGGADIRVVQELM
Mflv_4645|M.gilvum_PYR-GCK AAGLRTIFRYHRI--KSGVLAG-HPHALRHTFGTAMAEAGVDLAVMQALL
MMAR_1433|M.marinum_M AAGLRTVFRYHRE--RSGVAAG-HPHALRHSFGTALAEAGVDLSVIQALM
. . ** :**: .* : * *: :
TH_3114|M.thermoresistible__bu GHADIQTTLSTYGWVTEDAEMRTVAQWRNYVAGWKGLHHDDTP
Mvan_5418|M.vanbaalenii_PYR-1 GHADIQTTLSTYGWVTEDAEMRTLAQWRNYVAGWKGLTP----
MAB_0442|M.abscessus_ATCC_1997 GHQDIQTTLSTYGWVTEDAEMRSVAEWRNFVAGWKGLHDDPH-
MAV_0505|M.avium_104 GHADVQTTLSTYGWVTQDAEMRSLASWKNYVAGWKGLHDGPP-
MSMEG_4155|M.smegmatis_MC2_155 GHANVTVTAATYGHLNVEDARKAMEQAGWFIGKAQVKL-----
Mb1727|M.bovis_AF2122/97 GHASVTTTQ-IYTLVTVHALREVWAGAHPRAR-----------
Rv1701|M.tuberculosis_H37Rv GHASVTTTQ-IYTLVTVHALREVWAGAHPRAR-----------
MUL_1690|M.ulcerans_Agy99 GHASVTTTQ-IYTLVTVHALREVWAGAHPRAT-----------
MLBr_01365|M.leprae_Br4923 GHASVTTTQ-IYTLVTVQALREVWAGAHPRAK-----------
Mflv_4645|M.gilvum_PYR-GCK GHAHIDTTA-RYIHLAPTHVKAEYDAARTRLRSHT--------
MMAR_1433|M.marinum_M GHDHVDSAA-AYIHLAPTFLREEFDAARARLRARS--------
** : : * :