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MRQSVTRLHATLLSVIVAIAALAGCSRGPVQTGNVFVIAIESEADILDPQVAGGWVSWRINRQIFEPLVD EDLSMPSSEATVPPLRPGLAESWDISDDGLEYTFHIRKDVKFHDGTPLDARAVEYNVRRMWDKSSPMYNA RAAGQTGFVWKFLDSVQTVDDHTLKMRLSQPFSEFLRMLAQGGNGSTAIMSPTALQTYGEDVADHPVGTG PFKFKERIRGERIDLVRNDDYWGKVPYIDGVVFRPLPDPSARTAALRSGDVDMIAVPNPDSIDNLVSEGY QLSEGTPPHTWYLSFNMKDRYTSIPEVRQAINLAVDREGMAKDMLRGSVTPAWGVQALSAGGYVERKDIY QRNLDKARQLLASVGLADGFQTTLITSTDGSGQIMPAQMAEFIQQNLAEIGIKVNIQTQEWISYLGVWAR GMQDGVGMAQMSWGMTSPYWLYIVTSSELQAPNGPNVGYYSSPALDKAMNNAIIALDPQEAEQWWRRANN IVSDEAALVPIVNDKAPYVLAPYVSGFVSASEEWYDLTSVKLEQ
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_1084 | - | - | 100% (534) | peptide/opine/nickel uptake family protein ABC transporter, periplasmic substrate-binding protein, putative |
M. smegmatis MC2 155 | MSMEG_4354 | - | 5e-49 | 29.04% (513) | dipeptide-binding protein of ABC transport system |
M. smegmatis MC2 155 | MSMEG_4385 | - | 5e-46 | 30.25% (519) | ABC transporter oligopeptide binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1311c | oppA | 3e-17 | 22.00% (450) | periplasmic oligopeptide-binding lipoprotein OppA |
M. gilvum PYR-GCK | Mflv_2761 | - | 7e-53 | 29.77% (524) | extracellular solute-binding protein |
M. tuberculosis H37Rv | Rv1280c | oppA | 3e-17 | 22.00% (450) | periplasmic oligopeptide-binding lipoprotein OppA |
M. leprae Br4923 | MLBr_01121 | - | 3e-16 | 23.70% (443) | putative extracellular solute-binding dependent transport |
M. abscessus ATCC 19977 | MAB_0426 | - | 5e-21 | 25.88% (537) | peptide ABC transporter DppA |
M. marinum M | MMAR_4139 | oppA | 1e-14 | 20.70% (570) | periplasmic oligopeptide-binding lipoprotein OppA |
M. avium 104 | MAV_3421 | - | 1e-16 | 24.71% (425) | extracellular solute-binding protein, family protein 5 |
M. thermoresistible (build 8) | TH_4152 | - | 8e-47 | 28.93% (515) | PUTATIVE extracellular solute-binding protein, family 5 |
M. ulcerans Agy99 | MUL_4002 | oppA | 3e-14 | 21.00% (562) | periplasmic oligopeptide-binding lipoprotein OppA |
M. vanbaalenii PYR-1 | Mvan_3773 | - | 4e-48 | 28.00% (525) | extracellular solute-binding protein |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_2761|M.gilvum_PYR-GCK -----------------------------MARTAVGAAVLAVCALVLSLT Mvan_3773|M.vanbaalenii_PYR-1 ----------------------------------MRTVVLATCVFLAALT TH_4152|M.thermoresistible__bu -------------------------------------VSNLVAVLLIAAT Mb1311c|M.bovis_AF2122/97 MADRGQRRGCAPGIASALRASFQGKSRPWTQTRYWAFALLTPLVVAMVLT Rv1280c|M.tuberculosis_H37Rv MADRGQRRGCAPGIASALRASFQGKSRPWTQTRYWAFALLTPLVVAMVLT MMAR_4139|M.marinum_M MLTNADR---HDGVQPGPGARSRRPTRPWAR-RRIRCAGAALLTVTLLLA MUL_4002|M.ulcerans_Agy99 -----------------------------------------MLTVTLLLA MLBr_01121|M.leprae_Br4923 -------------------------------MIMLSRIVAALLVVGLILT MSMEG_1084|M.smegmatis_MC2_155 ---------------------------MRQSVTRLHATLLSVIVAIAALA MAB_0426|M.abscessus_ATCC_1997 --------------------------------MRLRRLAIVLLVGIVAVL MAV_3421|M.avium_104 ------------------------------MAKVASRTATLGAMLCVLAA Mflv_2761|M.gilvum_PYR-GCK GCNTG-ERVDLGDGAGGALIAAIAGEPDQLDPHKTT----AYFSFEVLEN Mvan_3773|M.vanbaalenii_PYR-1 GCSPG-DRVDLGAGAADALIAAIAGEPDQLDPHKTT----SYFSFEVLEN TH_4152|M.thermoresistible__bu GCAPG-QRVDLGD-LSGNLIAAIAGEPDQLDPHKTS----AYFSFQVLEN Mb1311c|M.bovis_AF2122/97 GCSASGTQLELAPTADRRAAVGTTSDINQQDPATLQDGGNLRLSLTDFPP Rv1280c|M.tuberculosis_H37Rv GCSASGTQLELAPTADRRAAVGTTSDINQQDPATLQDGGNLRLSLTDFPP MMAR_4139|M.marinum_M GCSAS-TQLPAATSGS--TAVGSSSDINPQDPATLEDGGDLRLSLTDFPP MUL_4002|M.ulcerans_Agy99 GCSAS-TQLPAATSGS--TAVGSSSDINPQDPATLEDGGDLRLSLTDFPP MLBr_01121|M.leprae_Br4923 GCSASNRLVPSAASNA---ALGKTSDINPQDPATLKDGGNLRLALTDFPA MSMEG_1084|M.smegmatis_MC2_155 GCSRG------PVQTGNVFVIAIESEADILDPQVAGGWVSWRINRQIFEP MAB_0426|M.abscessus_ATCC_1997 PAGCG---DLVTPAPPGYFSMYITEPEHTLVPGNTTE----NQGGRILRS MAV_3421|M.avium_104 GCSGHRHTASTGPTGPPVRGGTLTYSDVQFVTDTMA------ANYSANNL . . Mflv_2761|M.gilvum_PYR-GCK VFDTLVE----PDQDLQMKPALAESWEVSPD------------------- Mvan_3773|M.vanbaalenii_PYR-1 VFDTLVE----PDGNLQMQPALARAWEVSPD------------------- TH_4152|M.thermoresistible__bu VFDTLVE----PDEDLRMRPALAESWQVSAD------------------- Mb1311c|M.bovis_AF2122/97 NFNILHIDGNNAEVAAMMKATLPRAFIIGPDGSTTVDTNYFTSIELTRTA Rv1280c|M.tuberculosis_H37Rv NFNILHIDGNNAEVAAMMKATLPRAFIIGPDGSTTVDTNYFTSIELTRTA MMAR_4139|M.marinum_M NFNILHIDGNSAEVAAMVKATLPRAFIIGPDGSTTVDHDYFTSVELTKTN MUL_4002|M.ulcerans_Agy99 NFNILHIDGNSAEVAAMVKATLPRAFIIGPDGSTTVDHDYFTSVELTKTN MLBr_01121|M.leprae_Br4923 NFNILHIDGNNAEVTSMMKATMPRAFIIGTDGSTTVDTNYFTSIKLTSTS MSMEG_1084|M.smegmatis_MC2_155 LVDEDLSMPSSEATVPPLRPGLAESWDISDD------------------- MAB_0426|M.abscessus_ATCC_1997 LFTALVEFN--NETAAVEYTGVAESITSHDN------------------- MAV_3421|M.avium_104 MFQLLDRVVYVDPKTDAVRGWLAKTFSRNQN------------------- . :..: : Mflv_2761|M.gilvum_PYR-GCK QLTWTFRLRPGVTFHDGTPLAAEDVVFSYRRIID-----EQLANSDKF-- Mvan_3773|M.vanbaalenii_PYR-1 QLTWTFHLRPGVTFHDGTPLTADDVVFSYRRIID-----EQLANSDKF-- TH_4152|M.thermoresistible__bu QRVWTFRLRPGVTFHDGSPLTADDVVFSYRRIID-----EHLTNVDRL-- Mb1311c|M.bovis_AF2122/97 PQVVTYTINPEAVWSDGTPITWRDIASQIHAISGADKAFEIASSSGAE-- Rv1280c|M.tuberculosis_H37Rv PQVVTYTINPEAVWSDGTPITWRDIASQIHAISGADKAFEIASSSGAE-- MMAR_4139|M.marinum_M PQVITYTINPKAFWSDGTPITWRDIASQIHATSGADNRFEIASSGGSD-- MUL_4002|M.ulcerans_Agy99 PQVITYTINPKAFWSDGTPVTWRDIASQIHATSGADNRFEIASSGGSD-- MLBr_01121|M.leprae_Br4923 PQVVTYTINPKAVWSDGTPITWRDIDRQIHANSGKNKAFEIAGTNGCE-- MSMEG_1084|M.smegmatis_MC2_155 GLEYTFHIRKDVKFHDGTPLDARAVEYNVRRMWDKSSPMYNARAAGQTG- MAB_0426|M.abscessus_ATCC_1997 -VNWTIKLKPGWTFHNGEPVTAQSYVDAWNYTALSTNAQGSSSFLANVDG MAV_3421|M.avium_104 ATRYTFTIRDGVSFSDHTPLTAEVVKANFDQLGKGDPAKKMPAFADFVG- * :. : : *: Mflv_2761|M.gilvum_PYR-GCK ----------------SSVQAVEAPDPSTVVIRVDRPTPNMLTNLGG--- Mvan_3773|M.vanbaalenii_PYR-1 ----------------SSVAAVDAPDPNTVVIRVDRPTPNMLTNLGG--- TH_4152|M.thermoresistible__bu ----------------SAVTEVTAVDPLTVRITVARPTPNLLTNLGG--- Mb1311c|M.bovis_AF2122/97 ----------------RVASVTRGVDDRQAVVTFAKPYAEWRGMFAGNGM Rv1280c|M.tuberculosis_H37Rv ----------------RVASVTRGVDDRQAVVTFAKPYAEWRGMFAGNGM MMAR_4139|M.marinum_M ----------------RVASVTPGVDDRQAIVTFAKPYAEWRGMFAGNGM MUL_4002|M.ulcerans_Agy99 ----------------RVASVIPGVDDRQAMVTFAKPYAEWRGMFAGNGM MLBr_01121|M.leprae_Br4923 ----------------RVASIRPGANDRQAIVTFAQPYAEWRGMFAGNGM MSMEG_1084|M.smegmatis_MC2_155 -------------FVWKFLDSVQTVDDHTLKMRLSQPFSEFLRMLAQGGN MAB_0426|M.abscessus_ATCC_1997 FDDLQGDPAHKIAPRATQMRGLHVVDDVTFTVRLNTPFAIYPMTLGY--- MAV_3421|M.avium_104 -------------------YDHSEVSGNVVTVFLDRPNTNFYKVLSYSRA . : . * . :. Mflv_2761|M.gilvum_PYR-GCK -FKGMAIVSRANVESGRIATHPVGTGPFSFLGQ-KSGDSISLRANPDYWA Mvan_3773|M.vanbaalenii_PYR-1 -FKGMAIVSRANVESGRIATQPVGTGPFRFLGQ-KSGDSISLAANPNYWD TH_4152|M.thermoresistible__bu -FKGMAIVQRANVETGRIATHPVGTGPFEFRGA-RSGDSITLVANDDHWA Mb1311c|M.bovis_AF2122/97 LLPASMTATPEAFNKGQLDGPGPSAGPFVVSALDRTAQRIVLTRNPRWWG Rv1280c|M.tuberculosis_H37Rv LLPASMTATPEAFNKGQLDGPGPSAGPFVVSALDRTAQRIVLTRNPRWWG MMAR_4139|M.marinum_M LLPSSMTATPEAFNKGQLAGPGPSAGPFIVTSLDRSAQRIVLTRNPKWWG MUL_4002|M.ulcerans_Agy99 LLPSSMTATPEAFNKGQLTGPGPSAGPFIVTSLDRSAQRIVLIRNPKWWG MLBr_01121|M.leprae_Br4923 LLPATMTATPEAFNKGQLDRPGPSAGPFIVSSLDRTTQRIVLTHNPKWWG MSMEG_1084|M.smegmatis_MC2_155 GSTAIMSPTALQTYGEDVADHPVGTGPFKFKER-IRGERIDLVRNDDYWG MAB_0426|M.abscessus_ATCC_1997 -TAFLPLPKAFFRDPVKFGVHPIGNGPFKADGDWVRGVGFTLSRYDQYAG MAV_3421|M.avium_104 GIRAPATLALDYQRQAKVEN-VIGSGPFVYQSQIPDQQVVLTRRPDYAWP . . *** . Mflv_2761|M.gilvum_PYR-GCK -------GPPGVAGVTFRFIPEPSTALSALQAGEVDWTDSVPPQRVSQLR Mvan_3773|M.vanbaalenii_PYR-1 -------GPPGVSGVTYRFISEPSTALSALQAGEIDWTDSVPPQRVTQLR TH_4152|M.thermoresistible__bu -------GPPRLNGVTFRFISEPATALSALQAGEIDWTDAIPTQRVTQLR Mb1311c|M.bovis_AF2122/97 -------ARPRLDSITY-LVLDDAARLPALQNNTIDATGVGTLDQLTIAA Rv1280c|M.tuberculosis_H37Rv -------ARPRLDSITY-LVLDDAARLPALQNNTIDATGVGTLDQLTIAA MMAR_4139|M.marinum_M -------KKPRLDSITY-LVLDDAARIPALQNFTIDATGIGSLDQLTIAE MUL_4002|M.ulcerans_Agy99 -------KKPRLHSITY-LVLDDAARIPALQNFTIDATGIGSLDQLTIAE MLBr_01121|M.leprae_Br4923 -------TPPRLDSITY-LVLDDAARLPALQNNTIDATGVGTLDQLTTAQ MSMEG_1084|M.smegmatis_MC2_155 -------KVPYIDGVVFRPLPDPSARTAALRSGDVDMIAVPNPDSIDNLV MAB_0426|M.abscessus_ATCC_1997 E------KKAKAKGLIWRVYTEGLTAYTDMQAGALDIQLDLPDAAYENAK MAV_3421|M.avium_104 PSSWPNQGPAYVDKVVFRVIGEPGLRAGAVQSHQVDVARGIQPTDEPALK . : : : :: :* Mflv_2761|M.gilvum_PYR-GCK DDESLQLTVTPSNDYWYLALNQAR-APWNDVRVRQAIAYAIDRDAIVQAT Mvan_3773|M.vanbaalenii_PYR-1 DDESLELAVTPSNDYWYLALNEAR-EPWNDVRVRQAVAYAVDRDAIVQAT TH_4152|M.thermoresistible__bu NDDSLTLAVTPSNDYWYLALNHAR-APWHDLRVRRAIAFGIDREAIVTAT Mb1311c|M.bovis_AF2122/97 RTKGISIRRAPGPSWYHFTLNGAPGSILADKALRLAIAKGIDRYTIARVA Rv1280c|M.tuberculosis_H37Rv RTKGISIRRAPGPSWYHFTLNGAPGSILADKALRLAIAKGIDRYTIARVA MMAR_4139|M.marinum_M RTKGISIRRAPAPSWSHFTLNGAPGAVLADPALRLAVCKGIDRRTIAKVA MUL_4002|M.ulcerans_Agy99 RTKGISIRRAPAPSWSHFTLNGAPGAVLADPALRLAVCKGIDRRTIAKVA MLBr_01121|M.leprae_Br4923 RTNGISIRRTPAPRWSHFTFNGAVGSILADQGLRLAVSKGIDRRTIAKVV MSMEG_1084|M.smegmatis_MC2_155 S-EGYQLSEGTPPHTWYLSFNMKD-RYTSIPEVRQAINLAVDREGMAKDM MAB_0426|M.abscessus_ATCC_1997 AEFGSAYLERPRPDITSLGFPMYD-PRYRDVRVRQAISMAIDREAITQVI MAV_3421|M.avium_104 QGGLQVIPVAAPAETANLVGFRINNQVVDDVRVRRALQLGIDRRAVVDTV . : :* *: .:** :. Mflv_2761|M.gilvum_PYR-GCK SYGTAAANQLAIPEGNPWFTPYDR---YREDGEEGLETARDLLRQANAT- Mvan_3773|M.vanbaalenii_PYR-1 SYGTAAVNQLAIPQGNPWFTPYDR---YRDDGEQGLETARTLLREAGAQ- TH_4152|M.thermoresistible__bu GYGTATANQLAIPPGDFWYTHYDR---YRYD----LDRARALLDEARAAG Mb1311c|M.bovis_AF2122/97 QYG--LTSDPVPLNNHVFVAGQDG---YQDNSGVVAYNPEQAKRELDALG Rv1280c|M.tuberculosis_H37Rv QYG--LTSDPVPLNNHVFVAGQDG---YQDNSGVVAYNPEQAKRELDALG MMAR_4139|M.marinum_M LYG--LTNDPAPLNNHVFVAGQEG---YQDNS--SPYDPEQAKRELDALG MUL_4002|M.ulcerans_Agy99 LYG--LTNDPAPLNNHVFVAGQEG---YQDNS--SPYDPEQAKRELDALG MLBr_01121|M.leprae_Br4923 QYG--LANNPEPLNNHVYVDGQEG---YQDNSGVVGYDPEQAQHELDALG MSMEG_1084|M.smegmatis_MC2_155 LRG---SVTPAWGVQALSAGGYVE---RKDIYQRNLDKARQLLASVGLAD MAB_0426|M.abscessus_ATCC_1997 FSG---TRTPATSYGSAVVYGYRKGA-CGKLCELHVDEANKLLDEAHFDR MAV_3421|M.avium_104 LSDSYRAADSVLGHDDPLFADVSADIGYQPQRAAGLLDAAGWKPGGDGVR . . Mflv_2761|M.gilvum_PYR-GCK ---PGDLD---------MLVTTEYPETVTAAQIVADNLAPLGITVNIRTV Mvan_3773|M.vanbaalenii_PYR-1 ---PRELD---------MLVTTEYPETVTAAQIIADNLAPLGISVKIRTV TH_4152|M.thermoresistible__bu VDPPRRLD---------MLVTGDYPQTVTAAQIIADNVAPLGITVDIRTV Mb1311c|M.bovis_AF2122/97 WRRSGAFREKDGRQLVIRDLFYDAQSTRQFAQIAQHTLAQIGVKLELQAK Rv1280c|M.tuberculosis_H37Rv WRRSGAFREKDGRQLVIRDLFYDAQSTRQFAQIAQHTLAQIGVKLELQAK MMAR_4139|M.marinum_M WKLNGKFREKDGHQLVVRLLFYEAQSSRQFAQVAQYSLAQIGVKLELQSR MUL_4002|M.ulcerans_Agy99 WKLNGKFREKDGHQLVVRLLFYEAQSSRQFAQVAQYSLAQIGVKLELQSR MLBr_01121|M.leprae_Br4923 WKLNGQFREKDGRQLVIRYLFYDAQGSREFAQLAQHSLAQIGVKLELQAK MSMEG_1084|M.smegmatis_MC2_155 GFQTTLIT---------STDGSGQIMPAQMAEFIQQNLAEIGIKVNIQTQ MAB_0426|M.abscessus_ATCC_1997 NKPIELWYS-----------SSSTGALSWVQAIGNQLQSNLKVPYLLKSL MAV_3421|M.avium_104 EKDGKKLVLT-------LAASNQSVVFRPAFEFIEQQWRELGVVLQNRAG . : : :: Mflv_2761|M.gilvum_PYR-GCK DFATWLDE-QNSGNFDMLMMGWLGNIDPDD-FYYAQHHTDGTS----NAQ Mvan_3773|M.vanbaalenii_PYR-1 DFATWLDE-QNSGNFDMLMMGWLGNIDPDD-FYYAQHHTDGTS----NAQ TH_4152|M.thermoresistible__bu DFATWLDE-QNNGTFDMLMMGWLGNIDPDD-YYYAQHHTDGAS----NAQ Mb1311c|M.bovis_AF2122/97 SGSGFFSDYVNVGAFDIAQFGWVGDAFPLS-SLTQIYASDGES----NFG Rv1280c|M.tuberculosis_H37Rv SGSGFFSDYVNVGAFDIAQFGWVGDAFPLS-SLTQIYASDGES----NFG MMAR_4139|M.marinum_M SGSGFFSNYVNVGAFDIALFGWVGDAFPLS-SLTQIYMSDGES----NFG MUL_4002|M.ulcerans_Agy99 SGSGFFSNYVNVGAFDIALFGWVGDAFPLS-SLTQIYMSDGES----NFG MLBr_01121|M.leprae_Br4923 AGSGFFTNYVNVGAFDIVQFGWVGDAFPLS-ALTQIYQSDGES----NFG MSMEG_1084|M.smegmatis_MC2_155 EWISYLGVWARGMQDGVGMAQMSWGMTSPY-WLYIVTSSELQAPNGPNVG MAB_0426|M.abscessus_ATCC_1997 PWSQFLPLQDGKGMTGPFRSGWVMDYPSIYNFLESLYGTVALPPNGSNYV MAV_3421|M.avium_104 DTTFFNAS---SSQSSTPLFGTRIQYNIGLGLLFGRPKS--------NLT : . : * Mflv_2761|M.gilvum_PYR-GCK KFSNPEVDRLLDAGRVETDEQTRKAGYARAATLIADEVSYIYLYNPSVIQ Mvan_3773|M.vanbaalenii_PYR-1 KFSDPEVDRLLDASRVETDEAARKEQYAGAATLIADKVSYIYLYNPSVIQ TH_4152|M.thermoresistible__bu RFSDPEVDRLLDAARAEPDRDRRKALYDRAATLIADRVSYLFLYNPAVVQ Mb1311c|M.bovis_AF2122/97 KIGSPQIDAAIERTLAELDPGKARALANQVDELIWAEGFSLPLTQSPGTV Rv1280c|M.tuberculosis_H37Rv KIGSPQIDAAIERTLAELDPGKARALANQVDELIWAEGFSLPLTQSPGTV MMAR_4139|M.marinum_M KIGSPQIDAAIERTLQELDPAKALALANEVDKLIWAEGFSLPLTQSPGTI MUL_4002|M.ulcerans_Agy99 KIGSPQIDAAIERTLQELDPAKALALANQVDKLIWAEGFSLPLTQSPGTI MLBr_01121|M.leprae_Br4923 KISSPAVDAAIERTLAELDPAKARALANEVDKLLWAEGFSLPLTQSPGDV MSMEG_1084|M.smegmatis_MC2_155 YYSSPALDKAMNNAIIALDPQEAEQWWRRANNIVSDEAALVPIVNDKAPY MAB_0426|M.abscessus_ATCC_1997 FYSNPAFDELLRQGNNEPTVELATKAYQKAEDLLFKDLPAAPLFYEVNQA MAV_3421|M.avium_104 FAQNDALLALSEEELRQTDPTRLKDVVAREQRRIIDDQLALVLWDEVQVH . . : : Mflv_2761|M.gilvum_PYR-GCK AWNPALSGYEARRDGAVRFRSASLDSDGNV----- Mvan_3773|M.vanbaalenii_PYR-1 AWNPALSGYEARRDGAVRFRSATFGADGGA----- TH_4152|M.thermoresistible__bu AWSPDLSGYRARRDAAVRFRDASLNRDGLNRDGPP Mb1311c|M.bovis_AF2122/97 AVRSTLANFGATGLADLDYTAIGFMRR-------- Rv1280c|M.tuberculosis_H37Rv AVRSTLANFGATGLADLDYTAIGFMRR-------- MMAR_4139|M.marinum_M AVRSTLANFGARGLADLDYTAIGFMRS-------- MUL_4002|M.ulcerans_Agy99 AVRSTLANFGARGLADLDYTAIGFMRS-------- MLBr_01121|M.leprae_Br4923 AVRSTLANFGAAGFGDLNYTAIGFMQN-------- MSMEG_1084|M.smegmatis_MC2_155 VLAPYVSGFVSASEEWYDLTSVKLEQ--------- MAB_0426|M.abscessus_ATCC_1997 VHSKRVRNVKIGIQDCIEYADVEVVQ--------- MAV_3421|M.avium_104 AAAPNVHVEFTRYTEPLLQSAWKA----------- . :