For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
LGVASYLCVLAMTVASAGTASANPDELPVQTEALSSLMLEPGDVAPVMGAGMYVAGDWAALVSDRTDRPE CGSVVLASGASYESSNYLSGRYRSLIDSPNWTRLVDQSMVIFPEWSDATDFALAEADRWRACENQRVTSL LPQPDGSTRREWVQLRKIVQVQEVLVVGYTWPTDFGGVIYCQHALAPLRNVAIDVRACAERDGSRALDLI LGLLPRVARA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0358 | - | - | 100% (220) | membrane protein PknM or lipoprotein LppH |
| M. abscessus ATCC 19977 | MAB_0360 | - | 9e-36 | 40.65% (214) | hypothetical protein MAB_0360 |
| M. abscessus ATCC 19977 | MAB_0361 | - | 9e-23 | 32.85% (207) | hypothetical protein MAB_0361 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3607 | lppH | 2e-08 | 25.95% (185) | lipoprotein LppH |
| M. gilvum PYR-GCK | Mflv_2235 | - | 6e-10 | 24.53% (212) | putative lipoprotein LppH |
| M. tuberculosis H37Rv | Rv3576 | lppH | 4e-08 | 25.41% (185) | lipoprotein LppH |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_2444 | - | 3e-11 | 27.80% (205) | transmembrane serine/threonine-protein kinase |
| M. avium 104 | MAV_2123 | - | 2e-09 | 28.17% (213) | PknM protein |
| M. smegmatis MC2 155 | MSMEG_4596 | - | 2e-09 | 27.75% (173) | hypothetical protein MSMEG_4596 |
| M. thermoresistible (build 8) | TH_3756 | - | 7e-08 | 27.03% (185) | PUTATIVE putative conserved lipoprotein LppH |
| M. ulcerans Agy99 | MUL_4150 | lppH | 8e-10 | 26.48% (219) | lipoprotein LppH |
| M. vanbaalenii PYR-1 | Mvan_4460 | - | 4e-12 | 28.11% (217) | putative lipoprotein LppH |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3607|M.bovis_AF2122/97 --------------------------------------------------
Rv3576|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4150|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2235|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4460|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3756|M.thermoresistible__bu --------------------------------------------------
MAV_2123|M.avium_104 --------------------------------------------------
MMAR_2444|M.marinum_M MSDTVPTSRVGTQFGPYRLRRLLGRGGMGEVYEAHDTVKDRTVALKLMSQ
MAB_0358|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_4596|M.smegmatis_MC2_155 --------------------------------------------------
Mb3607|M.bovis_AF2122/97 --------------------------------------------------
Rv3576|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4150|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2235|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4460|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3756|M.thermoresistible__bu --------------------------------------------------
MAV_2123|M.avium_104 --------------------------------------------------
MMAR_2444|M.marinum_M QFNSDSTFRRRMQREAHTAGRLQEPHIVPIHDFGEIDGQLFIDMRFIEGT
MAB_0358|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_4596|M.smegmatis_MC2_155 --------------------------------------------------
Mb3607|M.bovis_AF2122/97 --------------------------------------------------
Rv3576|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4150|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2235|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4460|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3756|M.thermoresistible__bu --------------------------------------------------
MAV_2123|M.avium_104 --------------------------------------------------
MMAR_2444|M.marinum_M DLGSVLKRGALPAPRAVAIVSQVAEALDAAHRGGVVHRDIKPENILITGN
MAB_0358|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_4596|M.smegmatis_MC2_155 --------------------------------------------------
Mb3607|M.bovis_AF2122/97 --------------------------------------------------
Rv3576|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4150|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2235|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4460|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3756|M.thermoresistible__bu --------------------------------------------------
MAV_2123|M.avium_104 --------------------------------------------------
MMAR_2444|M.marinum_M DFAYLVDFGIAAAATDQHLTKTGTAVGSWSYMAPERFGDDEVTYRSDIYA
MAB_0358|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_4596|M.smegmatis_MC2_155 --------------------------------------------------
Mb3607|M.bovis_AF2122/97 --------------------------------------------------
Rv3576|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4150|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2235|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4460|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3756|M.thermoresistible__bu --------------------------------------------------
MAV_2123|M.avium_104 --------------------------------------------------
MMAR_2444|M.marinum_M LACVLYECLTGTPPYQTQNLSTLMGAHLMQPIPRPSRHRPDIPTAFDEVI
MAB_0358|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_4596|M.smegmatis_MC2_155 --------------------------------------------------
Mb3607|M.bovis_AF2122/97 --------------------------------------------------
Rv3576|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4150|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2235|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4460|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3756|M.thermoresistible__bu --------------------------------------------------
MAV_2123|M.avium_104 --------------------------------------------------
MMAR_2444|M.marinum_M ARGMAKDPALRYPTAGELARAARQALSAGDQERAATLIAGTHQLAAPPSG
MAB_0358|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_4596|M.smegmatis_MC2_155 --------------------------------------------------
Mb3607|M.bovis_AF2122/97 ---------------------MGKQLAALAALVG-ACMLAAG--CTNVVD
Rv3576|M.tuberculosis_H37Rv ---------------------MGKQLAALAALVG-ACMLAAG--CTNVVD
MUL_4150|M.ulcerans_Agy99 ---------------------MRQRVAALAALVGGAGMLVTG--CTNIVD
Mflv_2235|M.gilvum_PYR-GCK -------------------------MRR-AVAIAGIAIMVTG--CASTSS
Mvan_4460|M.vanbaalenii_PYR-1 -------------------------MRRKTVAILGICILVTG--CADTIS
TH_3756|M.thermoresistible__bu -----------------------------------MGVLVAG--CGSTGH
MAV_2123|M.avium_104 -------------------------MRRLAATLAAAGMLVAG--CGAGNH
MMAR_2444|M.marinum_M PMPWAPPPWTSPARRTRTPWLLAVAVLVVVIVVVGTGIFLARKEPASGPT
MAB_0358|M.abscessus_ATCC_1997 --------------------------MGVASYLCVLAMTVAS--------
MSMEG_4596|M.smegmatis_MC2_155 -------------------------------------MTTPK--------
: .
Mb3607|M.bovis_AF2122/97 G----TAVAADKSGPLHQDPIPVSALEGLLLDLSQINAALGATSMKVWFN
Rv3576|M.tuberculosis_H37Rv G----TAVAADKSGPLHQDPIPVSALEGLLLDLSQINAALGATSMKVWFN
MUL_4150|M.ulcerans_Agy99 G----NAVAADMSGPLNQTPIAVSALDDLLLDVSQIDSALGATSMKVWFN
Mflv_2235|M.gilvum_PYR-GCK ---AESAEPP--TRTMIPRPLVEREIGEVLLSPEEIAALMGVPAMTVIEA
Mvan_4460|M.vanbaalenii_PYR-1 SADAAGSARP--TRTMIPRPLVERELSELLLSPERAAAEMGVPAMTVIES
TH_3756|M.thermoresistible__bu ---AESTTAPSTTKTLIPRPLVERELPGLLLSPEQVNAAMGTTDMAIISS
MAV_2123|M.avium_104 G--AASSSTATGSTASPKTPLARGALPDLMLSPNDIDTALGVTGTTSDPP
MMAR_2444|M.marinum_M GGVSTTAGAPSGITATAGPTVAPTQLESFLLSPEQINTIVGTTGIVIDHN
MAB_0358|M.abscessus_ATCC_1997 --------AGTASANPDELPVQTEALSSLMLEPGDVAPVMG-AGMYVAGD
MSMEG_4596|M.smegmatis_MC2_155 --------PEPEPNAIHAGQLGRILGLGAGSGDVSISTVLGVEYLGKTAE
: . :*
Mb3607|M.bovis_AF2122/97 AKAMWD----WSKSVADKNCLAIDGPAQEKVYAGTGWTAMRGQRLDDSIN
Rv3576|M.tuberculosis_H37Rv AKAMWD----WSKSVADKNCLAIDGPAQEKVYAGTGWTAMRGQRLDDSID
MUL_4150|M.ulcerans_Agy99 AKAMWD----WSKNISDKNCLAVDGPAQDEVYAGTGWTAMRGQRMDDSVD
Mflv_2235|M.gilvum_PYR-GCK QTSLSD----HSDIMAPIECLAIDGAGELQVYANSDYRASR----DQSLN
Mvan_4460|M.vanbaalenii_PYR-1 QTTMSD----HSAIMEPPECLAIDGAAELSVYADTGYRAER----DQSLN
TH_3756|M.thermoresistible__bu QTSLSD----HSNTMAPPECLALDGAGEADVYADSGYRAAR----DHSLN
MAV_2123|M.avium_104 FTALGEDPVRRTDYTFPAECKYTTHAGLASEYAGSGSTAVYGYHDLAPTP
MMAR_2444|M.marinum_M ATEMTDP--GPENSLSTEQCLGALIGYQTRTYKSSGYTGML-----AQLM
MAB_0358|M.abscessus_ATCC_1997 WAALVS------DRTDRPECGSVVLASG-ASYESSNYLSGR----YRSLI
MSMEG_4596|M.smegmatis_MC2_155 FFGLSN------WSSDRPDCGGVLLPSLPQGYDNSGFIDTRTHVHDGAKP
: . :* * .:.
Mb3607|M.bovis_AF2122/97 DSKKRD--HYAIQAVVGFPTAHDAEEFYSSSVQSWSSCSNRR-FVEVTPG
Rv3576|M.tuberculosis_H37Rv DSKKRD--HYAIQAVVGFPTAHDAEEFYSSSVQSWSSCSNRR-FVEVTPG
MUL_4150|M.ulcerans_Agy99 DSKRRK--HYAIQAVVAFPSAHDASAFYNSSVRSWGNCSNRR-FTDVSTD
Mflv_2235|M.gilvum_PYR-GCK DGEGWK--TYVKQAVVLFPYLEKAGEFFDASVAQWPACR------EYTHT
Mvan_4460|M.vanbaalenii_PYR-1 DGEGWK--HYLKQSVVLFPYQEKAGEFFDASVRQWPACH------RYTHT
TH_3756|M.thermoresistible__bu NGDNFT--HYAKQAVVLFPLAETARAFFEASAEQWPACH------EYRHT
MAV_2123|M.avium_104 AGANQLESPEVYQFVVLFPSPEQASAFLSASSARWPACANRQDTVPADGT
MMAR_2444|M.marinum_M QKPRSTPGYVVVQGAVIFASADQAVGFVAAQADQWRSCAGKD--VTQVNN
MAB_0358|M.abscessus_ATCC_1997 DSPNWT--RLVDQSMVIFPEWSDATDFALAEADRWRACENQRVTSLLPQP
MSMEG_4596|M.smegmatis_MC2_155 GETDSR--MMAEQQATTFYTTTAAADFVTMAVTKWGKCANQVVTVNKPKS
* . * * * * *
Mb3607|M.bovis_AF2122/97 QDDAA--WTVADVVNDNGMLS---SSQVQ--EGGDGWTCQRALTARNNVT
Rv3576|M.tuberculosis_H37Rv QDDAA--WTVADVVNDNGMLS---SSQVQ--EGGDGWTCQRALTARNNVT
MUL_4150|M.ulcerans_Agy99 QPDTI--WTVSDVVNDNGMLS---TSQVQ--EAGDGWTCQRALTVRNNVA
Mflv_2235|M.gilvum_PYR-GCK QSGSV--WNPGEITSADRTLS---TVAMQRDAAAPGWGCGRALVHRNNVI
Mvan_4460|M.vanbaalenii_PYR-1 QSGSQ--WTVGEITVDGGMLS---TVAMQQDAAAPGWGCGRALARRNNVI
TH_3756|M.thermoresistible__bu QSGTK--WYVAELTRDGDILK---AITVQRDAGHPGWGCGRALVLRNNII
MAV_2123|M.avium_104 NPELR--WKVGPVTNANGMLSSQVTVTVNGNGVNVTMPCQRALTARNNIV
MMAR_2444|M.marinum_M GKTSR--WTFREVSGAPPKIS------LQRDLADSVVVCQHVLSAVSNIV
MAB_0358|M.abscessus_ATCC_1997 DGSTR--REWVQLRKIVQVQEVLVVGYTWPTDFGGVIYCQHALAPLRNVA
MSMEG_4596|M.smegmatis_MC2_155 SENPREPYIVGEPAMVDGILT---VTATRQGPPEDPWQCQHSLTSRRNVV
* : * *:
Mb3607|M.bovis_AF2122/97 IDIVTCAYSQPDLVAIGIANQIAAKVAKQ-
Rv3576|M.tuberculosis_H37Rv IDIVTCAYSQPDLVAIGIANQIAAKVAKQ-
MUL_4150|M.ulcerans_Agy99 IDVVTCAYSQSGSVAADVAQQIAAKAAKQ-
Mflv_2235|M.gilvum_PYR-GCK VDVNTCSAA-PGDSAVRIAHQIADKVDAQW
Mvan_4460|M.vanbaalenii_PYR-1 VDVNTCSAE-PGDSAVRIARQITANVDAQW
TH_3756|M.thermoresistible__bu GDVNTCSAD-PGDSAVRIAQQIGENVDAVW
MAV_2123|M.avium_104 IDVDACRKD-VGDLGIDIAKQIAGKVDKQ-
MMAR_2444|M.marinum_M LDVNVCAPN-VTDQASEIADTMAAKVPT--
MAB_0358|M.abscessus_ATCC_1997 IDVRACAER-DGSRALDLILGLLPRVARA-
MSMEG_4596|M.smegmatis_MC2_155 IDVAICAPT-GSTQAPLLARWSADRVPQ--
*: * . : ..