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MTIVLSAALACAAPALAEQGSPIPPAAIDDLMVTPDEASSVMKTGFPVVDRFNALSALTTDRPDCGSVVL PSVATYDRGPYMAAHQQYLQDSAPWNVQLAQSIAVFPTDDEARDFASTEMDMWLKCSKHTVHDSAQWRYA IGSLHRDDDAVVGSYVMITNDGARMSCSRLLARVRNTATDLRACSAGPESYQRLLGIAKIIGPRYDAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0361 | - | - | 100% (208) | hypothetical protein MAB_0361 |
| M. abscessus ATCC 19977 | MAB_0360 | - | 5e-38 | 44.55% (211) | hypothetical protein MAB_0360 |
| M. abscessus ATCC 19977 | MAB_0358 | - | 8e-23 | 32.85% (207) | membrane protein PknM or lipoprotein LppH |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1297c | pknH | 5e-08 | 23.08% (182) | transmembrane serine/threonine-protein kinase H |
| M. gilvum PYR-GCK | Mflv_2235 | - | 2e-09 | 23.62% (199) | putative lipoprotein LppH |
| M. tuberculosis H37Rv | Rv1266c | pknH | 5e-08 | 23.08% (182) | transmembrane serine/threonine-protein kinase H |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_1417 | - | 8e-08 | 25.14% (179) | serine/threonine-protein kinase PknE |
| M. smegmatis MC2 155 | MSMEG_4597 | lppH | 4e-11 | 27.23% (213) | putative lipoprotein lpph |
| M. thermoresistible (build 8) | TH_3555 | - | 3e-09 | 25.52% (192) | PUTATIVE - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4460 | - | 3e-12 | 25.13% (195) | putative lipoprotein LppH |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1297c|M.bovis_AF2122/97 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAE
Rv1266c|M.tuberculosis_H37Rv MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAE
MAV_1417|M.avium_104 MSDERSSKVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLLNES
Mflv_2235|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4460|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3555|M.thermoresistible__bu --------------------------------------------------
MSMEG_4597|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0361|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1297c|M.bovis_AF2122/97 FSKDPVFRERMKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTD
Rv1266c|M.tuberculosis_H37Rv FSKDPVFRERMKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTD
MAV_1417|M.avium_104 FSSDPVFRERMKREARTAGRLQEPHVVPVHDYGEIDGQMFLEMRLVEGTD
Mflv_2235|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4460|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3555|M.thermoresistible__bu --------------------------------------------------
MSMEG_4597|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0361|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1297c|M.bovis_AF2122/97 LDSVLKRFGPLTPPRAVAIITQIASALDAAHADGVMHRDVKPQNILITRD
Rv1266c|M.tuberculosis_H37Rv LDSVLKRFGPLTPPRAVAIITQIASALDAAHADGVMHRDVKPQNILITRD
MAV_1417|M.avium_104 LDSVLKRFGPLPPPRAVAIITQIASALDAAHAAGVMHRDVKPQNILVTRD
Mflv_2235|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4460|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3555|M.thermoresistible__bu --------------------------------------------------
MSMEG_4597|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0361|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1297c|M.bovis_AF2122/97 DFAYLVDFGIASATTDEKLTQLGTAVGTWKYMAPERFSNDEVTYRADIYA
Rv1266c|M.tuberculosis_H37Rv DFAYLVDFGIASATTDEKLTQLGTAVGTWKYMAPERFSNDEVTYRADIYA
MAV_1417|M.avium_104 DFAYLVDFGIASATTDEKLTQLGTAVGTWKYMAPERFSDAEVTYRADIYA
Mflv_2235|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4460|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3555|M.thermoresistible__bu --------------------------------------------------
MSMEG_4597|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0361|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1297c|M.bovis_AF2122/97 LACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRPGIPKAFDAVV
Rv1266c|M.tuberculosis_H37Rv LACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRPGIPKAFDAVV
MAV_1417|M.avium_104 LACVLFECLTGSAPYRADSAGVLVSAHVMDPIPAPSARRPGVPKAFDAVI
Mflv_2235|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4460|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3555|M.thermoresistible__bu --------------------------------------------------
MSMEG_4597|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0361|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1297c|M.bovis_AF2122/97 ARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPG--
Rv1266c|M.tuberculosis_H37Rv ARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP
MAV_1417|M.avium_104 ARGMAKKPEDRYASAGDLALAAKEALSTPDQDRAATILRRSQEAALPAAG
Mflv_2235|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4460|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3555|M.thermoresistible__bu --------------------------------------------------
MSMEG_4597|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0361|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1297c|M.bovis_AF2122/97 ---------TAAVTAQPPTMPTVTPPPIQAAP------------------
Rv1266c|M.tuberculosis_H37Rv KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPG
MAV_1417|M.avium_104 QR------DAGASTVLAPPPAVNTRQPGSAAS------------------
Mflv_2235|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4460|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3555|M.thermoresistible__bu --------------------------------------------------
MSMEG_4597|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0361|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1297c|M.bovis_AF2122/97 -TGQPSWAPNSGPMPASGPTPTPQYYQGG--GWGAPPS--GGPSPWAQTP
Rv1266c|M.tuberculosis_H37Rv PTGQPSWAPNSGPMPASGPTPTPQYYQGG--GWGAPPS--GGPSPWAQTP
MAV_1417|M.avium_104 -QAGRGWTPESGPIPAAG-QPGPPYYQGGNANWAAAPAQFAGPPPWGRPP
Mflv_2235|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4460|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3555|M.thermoresistible__bu ----------------------------------------------MTKL
MSMEG_4597|M.smegmatis_MC2_155 -------------------------------------------MIPVAPL
MAB_0361|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1297c|M.bovis_AF2122/97 RKTNPWPLVAGAAAVVLVLVLGAIGIWIANRPKPVQP-PQPVAEERLSAL
Rv1266c|M.tuberculosis_H37Rv RKTNPWPLVAGAAAVVLVLVLGAIGIWIAIRPKPVQP-PQPVAEERLSAL
MAV_1417|M.avium_104 PKRRVWPIVA-AVVAVLVVIAGGVGVWLVIRPKPEPPQAAPLTSDRLGAL
Mflv_2235|M.gilvum_PYR-GCK MRR-AVAIAGIAIMVTGCASTSS---AESAEPPTRTMIPRPLVEREIGEV
Mvan_4460|M.vanbaalenii_PYR-1 MRRKTVAILGICILVTGCADTISSADAAGSARPTRTMIPRPLVERELSEL
TH_3555|M.thermoresistible__bu TRRILGGCAAAVVVLTGAACTHSVEGSAVYAPEVPRDDLPLVKIAELRDL
MSMEG_4597|M.smegmatis_MC2_155 RRRRPSPLTLAAIVATVVALALAAAAVVVSVSG-----IGNVPSAALKGL
MAB_0361|M.abscessus_ATCC_1997 -------------------MTIVLSAALACAAPALAEQGSPIPPAAIDDL
: : :
Mb1297c|M.bovis_AF2122/97 LLNSSEVNAVMGSSSMQPGKPITSMDSSP-VTVSLPDCQGALYTSQDPVY
Rv1266c|M.tuberculosis_H37Rv LLNSSEVNAVMGSSSMQPGKPITSMDSSP-VTVSLPDCQGALYTSQDPVY
MAV_1417|M.avium_104 LLSASEVNAVMGSSTMEPGKPITATDSSS-VTVSVPDCQGALYTTQDPVY
Mflv_2235|M.gilvum_PYR-GCK LLSPEEIAALMGVPAMTVIEAQTSLSDHS-DIMAPIECLAIDGAGELQVY
Mvan_4460|M.vanbaalenii_PYR-1 LLSPERAAAEMGVPAMTVIESQTTMSDHS-AIMEPPECLAIDGAAELSVY
TH_3555|M.thermoresistible__bu IPTADEARTVVEAPNLIYLLAYTKPDSLPPDMLSEPECASAVIPNDASAY
MSMEG_4597|M.smegmatis_MC2_155 LLTPQEVAKAHGAQAIEVISDDDSLDSNE----PDSECLGLLNDRAERAY
MAB_0361|M.abscessus_ATCC_1997 MVTPDEASSVMKTG-FPVVDRFNALSALT---TDRPDCGSVVLPS-VATY
: .... : . :* . .*
Mb1297c|M.bovis_AF2122/97 AGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSADKWKN
Rv1266c|M.tuberculosis_H37Rv AGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSADKWKN
MAV_1417|M.avium_104 AGSGYSAVNGLVSSEPGDNYDHWVNQAVVLFPSADKAKSFLQTSLQKWKG
Mflv_2235|M.gilvum_PYR-GCK ANSDYRASRDQSLND-GEGWKTYVKQAVVLFPYLEKAGEFFDASVAQWPA
Mvan_4460|M.vanbaalenii_PYR-1 ADTGYRAERDQSLND-GEGWKHYLKQSVVLFPYQEKAGEFFDASVRQWPA
TH_3555|M.thermoresistible__bu RGSGYAAVYGRLADD---LRSHRISTGVAAFAGAQEAHEWVTQQVDRWRD
MSMEG_4597|M.smegmatis_MC2_155 RGSGWRAVHHQSLAD--QARHVMFSQSLIAMSDIHGAARYVDEQHALWKV
MAB_0361|M.abscessus_ATCC_1997 DRGPYMAAHQQYLQD-SAPWNVQLAQSIAVFPTDDEARDFASTEMDMWLK
: * : . .: :. . * : . *
Mb1297c|M.bovis_AF2122/97 CAGKTVTVTN-KAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSV
Rv1266c|M.tuberculosis_H37Rv CAGKTVTVTN-KAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSV
MAV_1417|M.avium_104 CAGQTVTVTN-KSKTYRWTFAQVQGAPPKITLMDTQEGADGWECQRALSV
Mflv_2235|M.gilvum_PYR-GCK CR--EYTHTQ-SGSVWNPGEITSADRTLSTVAMQRDAAAPGWGCGRALVH
Mvan_4460|M.vanbaalenii_PYR-1 CH--RYTHTQ-SGSQWTVGEITVDGGMLSTVAMQQDAAAPGWGCGRALAR
TH_3555|M.thermoresistible__bu CTDRTLTISL-NGQELQWKTSGPTRAEGVHVLLRRQEGTD-YACSRGVAA
MSMEG_4597|M.smegmatis_MC2_155 CSAQVLHRKNEDGLVADYVVTMVKRSDGILAASYHRDGGDGRTCVRGMAW
MAB_0361|M.abscessus_ATCC_1997 CSKHTVHDSA--QWRYAIGSLHRDDDAVVGSYVMITNDGARMSCSRLLAR
* . * * :
Mb1297c|M.bovis_AF2122/97 ANNVVVDVNACGYQI---TNQAGQIAAKIVDKVNKE-
Rv1266c|M.tuberculosis_H37Rv ANNVVVDVNACGYRI---TNQAGQIAAKIVDKVNKE-
MAV_1417|M.avium_104 ANNVIVDINACGYRI---TDQGDQIADKIVAKIDNE-
Mflv_2235|M.gilvum_PYR-GCK RNNVIVDVNTCSAAP---GDSAVRIAHQIADKVDAQW
Mvan_4460|M.vanbaalenii_PYR-1 RNNVIVDVNTCSAEP---GDSAVRIARQITANVDAQW
TH_3555|M.thermoresistible__bu RSNVAADVLVCGRNPEAVNPQAGKLANLMLSKIGD--
MSMEG_4597|M.smegmatis_MC2_155 RRNVVIDVTTCGPGP--TLWRLPGIIVPISARIQEA-
MAB_0361|M.abscessus_ATCC_1997 VRNTATDLRACSAGPE-SYQRLLGIAKIIGPRYDAA-
*. *: .*. : : .