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M. thermoresistible (build 8) TH_4628 (-)

annotation: conserved hypothetical protein
coordinates: 4407373 - 4408245
length: 291

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4628--100% (291)conserved hypothetical protein
M. thermoresistible (build 8)TH_1574-6e-4838.63% (277) CONSERVED HYPOTHETICAL PROTEIN
M. thermoresistible (build 8)TH_1589-1e-4437.86% (280) CONSERVED HYPOTHETICAL PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0849-2e-4639.19% (273) hypothetical protein Mb0849
M. gilvum PYR-GCKMflv_0060-1e-13275.17% (294) hypothetical protein Mflv_0060
M. tuberculosis H37RvRv0826-1e-4639.19% (273) hypothetical protein Rv0826
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4646-4e-7146.18% (288) hypothetical protein MAB_4646
M. marinum MMMAR_0288-2e-7952.22% (270) hypothetical protein MMAR_0288
M. avium 104MAV_5226-2e-8451.37% (292) hypothetical protein MAV_5226
M. smegmatis MC2 155MSMEG_5767-7e-4636.53% (271) hypothetical protein MSMEG_5767
M. ulcerans Agy99MUL_4835-2e-7552.53% (257) hypothetical protein MUL_4835
M. vanbaalenii PYR-1Mvan_0854-1e-13274.83% (290) hypothetical protein Mvan_0854

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0060|M.gilvum_PYR-GCK          ----------------------------------------MTELADKNGH
Mvan_0854|M.vanbaalenii_PYR-1       MRAVNLVTASLVQSAESVTLLP------------------MTELAQQTEH
TH_4628|M.thermoresistible__bu      ----------------------------------------MTELVETPQD
MMAR_0288|M.marinum_M               --------MATELTAGVDFDTG------------------VREALPMPI-
MUL_4835|M.ulcerans_Agy99           --------MATELTAGVDFDTG------------------VREALPMPI-
MAV_5226|M.avium_104                ---------MTAQRAAWDFDNG------------------VREAVPMPN-
MAB_4646|M.abscessus_ATCC_1997      ----------MVDQSALTLDEG------------------LREAIPMPVE
Mb0849|M.bovis_AF2122/97            ---------MTQDTSATCPLTSTVQDSSPVAGQLGRPIGFRGLAGGCPVS
Rv0826|M.tuberculosis_H37Rv         ---------MTQDTSATCPLTSTVQDSSPVAGQLGRPIGFRGLAGGCPVS
MSMEG_5767|M.smegmatis_MC2_155      ---------MTQDTSETCPVTS----------------GSARPAAGCPAA
                                                                                      

Mflv_0060|M.gilvum_PYR-GCK          LDG-----ADTDALPLGPQSLVWRYFGDNRMYLIG-PRPAVLQNMLAELG
Mvan_0854|M.vanbaalenii_PYR-1       LD---------DALPLGPQSLVWKYFGDNRMYLIG-PRPAVLQNMLAELG
TH_4628|M.thermoresistible__bu      ARR-----DTPDALPLGPDSLVWRYFGDNRMPLIG-PRPAVLQNMLAELG
MMAR_0288|M.marinum_M               DRP---VDDEIVAQRLGPTSLIWKFYGDVRTQLFGFQRAAGTENCIEQLG
MUL_4835|M.ulcerans_Agy99           DRP---VDDEIVAQRLGPTSLIWKFYGDVRTQLFGFQRAAGTENCIEQLG
MAV_5226|M.avium_104                DGPDWSARDAADAPRLGPDSLIWKFYGDNRTQLFGFQRTAGVENCIEQLA
MAB_4646|M.abscessus_ATCC_1997      DKP------DEPSLRLGADSLVWKFYGDIR-GVLGFQRLAGTENCIEQLG
Mb0849|M.bovis_AF2122/97            PLG-----YESPPLPLGPDSLTWRYFGDWRGMLQG-PWAGSMQNMHPQLG
Rv0826|M.tuberculosis_H37Rv         PLG-----YESPPLPLGPDSLTWRYFGDWRGMLQG-PWAGSMQNMHPQLG
MSMEG_5767|M.smegmatis_MC2_155      LGG-----YEAPPEVLGPDSLTWKIFGDWRGLLQG-PWAGSMQNMHPQLG
                                                .  **. ** *: :** *  : *    .  :*   :*.

Mflv_0060|M.gilvum_PYR-GCK          QGVYDHSTFFADTAERLKRTIPPILNTVYGSD-EENAGLQVRDFHHHVKG
Mvan_0854|M.vanbaalenii_PYR-1       QGVYDHSTFFADTAERLKRTIPPIFNTVYGSD-ENNAGLQVRDFHHHVKG
TH_4628|M.thermoresistible__bu      QGVLDHSVFFSDTAARVRRSLPPIFMTVYGSD-DENPGRQVRDYHTEIKG
MMAR_0288|M.marinum_M               QGVLDHSVVFSDTLGRAKRTGPPLMRTVYSED-PHGWGRTVRDFHKPIKG
MUL_4835|M.ulcerans_Agy99           QGVLDHSVVFSDTLGRAKRTGSPLMRPVYSED-PHGWGRTVRDFHKPIKG
MAV_5226|M.avium_104                QGVLDHSVIFSDTLGRAKRTAPPLMNTVYSDD-PQEWGRKVRDFHKTIKG
MAB_4646|M.abscessus_ATCC_1997      KAVEDHSVIFTDTIGRARRSGPPIMKTIYSAD-PQKWGRMVRDFHKPITG
Mb0849|M.bovis_AF2122/97            AAVEDHSTFFRGRWPRLLRSLYPIGGVVFDGDRAPVTGVQVRDYHITIKG
Rv0826|M.tuberculosis_H37Rv         AAVEDHSTFFRERWPRLLRSLYPIGGVVFDGDRAPVTGVQVRDYHITIKG
MSMEG_5767|M.smegmatis_MC2_155      AAVEEHSIFFRERIPRLLRSLYPIGGVVFDGDRAPQTGAQVRDYHIGIKG
                                     .* :** .*     *  *:  *:   ::. *     *  ***:*  :.*

Mflv_0060|M.gilvum_PYR-GCK          VMPGPDGEEAGRYHALDPETYFWAHATFVEQVYYFADTFVKRLTDAEREQ
Mvan_0854|M.vanbaalenii_PYR-1       EMPGTDG---ARYHALDPETYFWAHATFVEQIYYFADTFVKRLTDAEREQ
TH_4628|M.thermoresistible__bu      TMP--DG---QRYHALDPETYFWAHATFVDQVLYFADTFVKRLTRAEKEQ
MMAR_0288|M.marinum_M               TIG--DG---SRYHALNPELFYWAHATFVDQILYNTDTFIRRLSRAEKEQ
MUL_4835|M.ulcerans_Agy99           TIG--DG---SRYHALNPELFYWAHATFVDQILYNTDTFIRRLSRAEKEQ
MAV_5226|M.avium_104                TIS--DG---SRYHALNPELFYWAHASFVDQVIYNTDTFIRRLTRAEKEQ
MAB_4646|M.abscessus_ATCC_1997      TIS--DG---TRYHALNPELFYWAHATFVDQVLYITDTFIRRLSYEEKVR
Mb0849|M.bovis_AF2122/97            VDG--AG---RRYHALNPDVFYWAHATFFVGTLHVAERFCGGLTEAQRRQ
Rv0826|M.tuberculosis_H37Rv         VDG--AG---RRYHALNPDVFYWAHATFFVGTLHVAERFCGGLTEAQRRQ
MSMEG_5767|M.smegmatis_MC2_155      VDS--QG---RRYSALNPDVFYWAHSTFFMGTILTAERFGGGLTEDQKRQ
                                          *    ** **:*: ::***::*.      :: *   *:  :: :

Mflv_0060|M.gilvum_PYR-GCK          IWLESKTWYRRYGVSDRVMPATYAEFVQYWDRMMDQVVVAHPTAKYGVGY
Mvan_0854|M.vanbaalenii_PYR-1       IWLESKTWYRRYGVSDRPMPATYAEFEQYWDRMMDQVVVAHPSAKYGVGY
TH_4628|M.thermoresistible__bu      IYLESKTWYRRYGVSDRVMPATYDEFERYWDRMLDEIIVAHKTAKYGVGY
MMAR_0288|M.marinum_M               IFEESKIWYGLYGVSDRSQPQTYDEFVAYWDGMLDR-FVPHKTVLYGTGY
MUL_4835|M.ulcerans_Agy99           IFEESKIWYGLYGVSDRSQPQTYDEFVAYWDGMLDR-FVPHKTVLYGTGY
MAV_5226|M.avium_104                IFNEGKVWYSLYGVSDRGQPQTYDDFLAYWDEMLDR-FVPHKTVLYGTGY
MAB_4646|M.abscessus_ATCC_1997      IFEESKVWYSLYGVSARNQPQTYDEFVTYMESMFDR-FVPTKTILYATGY
Mb0849|M.bovis_AF2122/97            LFDEHVQWYRMYGMSMRPVPATWEEFQDYWDHMCRNVLENNFAARAVLDL
Rv0826|M.tuberculosis_H37Rv         LFDEHVQWYRMYGMSMRPVPATWEEFQDYWDHMCRNVLENNFAARAVLDL
MSMEG_5767|M.smegmatis_MC2_155      LFDEHIVWYRQYGMSMRPVPKTWEEFQEYWDHICRNVLENNYAAREVLDL
                                    :: *   **  **:* *  * *: :*  * : :  . .    :     . 

Mflv_0060|M.gilvum_PYR-GCK          VTKG-FPKPKAVHPLVWRLVAPVFNPLAAFLTTGGLPPRARMLLGLPWSD
Mvan_0854|M.vanbaalenii_PYR-1       VTKG-FPKPKAVHPLVWRLVAPVFNPLAAFLTTGGLPPRARMLLGLPWTD
TH_4628|M.thermoresistible__bu      VTKG-FPCPKGVHPAVWKVISVVFDPVAAFLTTGGLPPRARTLLNLPWSE
MMAR_0288|M.marinum_M               LRKG-IPGPRKLPALIWRILSAPLNAYARLVIVGTLPPQMREVCDLDWNA
MUL_4835|M.ulcerans_Agy99           LRKG-IPGPRKLPALIWRILSAPLNAYARLVIVGTLPPQMREVCDLDWNA
MAV_5226|M.avium_104                LRKG-IPGPRWMPRPVWKIVSAPLNAYARLVVVGTLPPQMREVCQLRWDA
MAB_4646|M.abscessus_ATCC_1997      IRQG-LPGPRQIPRPLWKVLSAPLNAFIRTVVVGTLPPQMKDVCRLQWSD
Mb0849|M.bovis_AF2122/97            TELPKPPFAQRVPDWLWAAPRKLLARFFVWLTVGLYDPPVRELMGYRWLR
Rv0826|M.tuberculosis_H37Rv         TELPKPPFAQRVPDWLWAAPRKLLARFFVWLTVGLYDPPVRELMGYRWLR
MSMEG_5767|M.smegmatis_MC2_155      STMPKHPSLEWIPDWLWKLNLKILGPFAVWVTVGLYDPPVRELMGYTWSD
                                          *  . :   :*      :      : .*   *  : :    *  

Mflv_0060|M.gilvum_PYR-GCK          KQERRYQRFAAFWRSRPVNWVWDRLPMTVRYSGYAVKGFTRSDMRSDVRA
Mvan_0854|M.vanbaalenii_PYR-1       KQERRYQRFAAIWRSRPVNWIWDRLPMRVRYSGYAVKGYARN--------
TH_4628|M.thermoresistible__bu      KQERRYQRFAAFCRSRPVNWVWDRLPMKVRYNKYARRGYARAA-------
MMAR_0288|M.marinum_M               KKERRFQRFAALIRG--LNPVLGRLPVRLIYLPWAAQAWTRSGVDPRRLH
MUL_4835|M.ulcerans_Agy99           KKERRFQRSAALIRG--LNPVLGRLPVRLIDLPWAAQARTRSGVDPRRLH
MAV_5226|M.avium_104                KKEKRFQRFAALMRA--LNPLINRLPVRVLYTPWAAQAWSRAGVDPRRLH
MAB_4646|M.abscessus_ATCC_1997      KKERNFRRFAALMRA--LNPVFNRLPVRWLYLPWAAEGWKREGVDPRPLH
Mb0849|M.bovis_AF2122/97            RDEWLHRRFGDIVQL-----VFALVPFRFRKHPRARAGWDRATGRIPADA
Rv0826|M.tuberculosis_H37Rv         RDEWLHRRFGDIVRL-----VFALVPFRFRKHPRARAGWDRATGRIPADA
MSMEG_5767|M.smegmatis_MC2_155      RDEKLHRLFGKAVHY-----TFKMLPERRRRHPRARAGWDRAQGRIPADA
                                    :.*  .:  .   :          :*        *  .  *         

Mflv_0060|M.gilvum_PYR-GCK          ----------------------------
Mvan_0854|M.vanbaalenii_PYR-1       ----------------------------
TH_4628|M.thermoresistible__bu      ----------------------------
MMAR_0288|M.marinum_M               RRAVST----------------------
MUL_4835|M.ulcerans_Agy99           RRAVST----------------------
MAV_5226|M.avium_104                NRAAA-----------------------
MAB_4646|M.abscessus_ATCC_1997      NRVA------------------------
Mb0849|M.bovis_AF2122/97            PLVQTPARNLPPPDERDNPTHYCPKV--
Rv0826|M.tuberculosis_H37Rv         PLVQTPARNLPPPDERDNPTHYCPKV--
MSMEG_5767|M.smegmatis_MC2_155      PLVETPARNLPPLDARDSPWHYCPAVTK