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TELADKNGHLDGADTDALPLGPQSLVWRYFGDNRMYLIGPRPAVLQNMLAELGQGVYDHSTFFADTAERL KRTIPPILNTVYGSDEENAGLQVRDFHHHVKGVMPGPDGEEAGRYHALDPETYFWAHATFVEQVYYFADT FVKRLTDAEREQIWLESKTWYRRYGVSDRVMPATYAEFVQYWDRMMDQVVVAHPTAKYGVGYVTKGFPKP KAVHPLVWRLVAPVFNPLAAFLTTGGLPPRARMLLGLPWSDKQERRYQRFAAFWRSRPVNWVWDRLPMTV RYSGYAVKGFTRSDMRSDVRA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0060 | - | - | 100% (302) | hypothetical protein Mflv_0060 |
| M. gilvum PYR-GCK | Mflv_1670 | - | 3e-41 | 37.25% (255) | hypothetical protein Mflv_1670 |
| M. gilvum PYR-GCK | Mflv_3536 | - | 7e-39 | 32.99% (288) | hypothetical protein Mflv_3536 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0849 | - | 3e-44 | 38.06% (289) | hypothetical protein Mb0849 |
| M. tuberculosis H37Rv | Rv0826 | - | 1e-44 | 38.06% (289) | hypothetical protein Rv0826 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4646 | - | 3e-61 | 41.84% (282) | hypothetical protein MAB_4646 |
| M. marinum M | MMAR_0288 | - | 4e-72 | 48.73% (275) | hypothetical protein MMAR_0288 |
| M. avium 104 | MAV_5226 | - | 4e-73 | 47.31% (279) | hypothetical protein MAV_5226 |
| M. smegmatis MC2 155 | MSMEG_5767 | - | 1e-41 | 33.91% (289) | hypothetical protein MSMEG_5767 |
| M. thermoresistible (build 8) | TH_4628 | - | 1e-132 | 75.17% (294) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4835 | - | 4e-68 | 47.27% (275) | hypothetical protein MUL_4835 |
| M. vanbaalenii PYR-1 | Mvan_0854 | - | 1e-161 | 90.48% (294) | hypothetical protein Mvan_0854 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0060|M.gilvum_PYR-GCK ----------------------------------------MTELADKNGH
Mvan_0854|M.vanbaalenii_PYR-1 MRAVNLVTASLVQSAESVTLLP------------------MTELAQQTEH
TH_4628|M.thermoresistible__bu ----------------------------------------MTELVETPQD
MMAR_0288|M.marinum_M --------MATELTAGVDFDTG------------------VREALPMPI-
MUL_4835|M.ulcerans_Agy99 --------MATELTAGVDFDTG------------------VREALPMPI-
MAV_5226|M.avium_104 ---------MTAQRAAWDFDNG------------------VREAVPMPN-
MAB_4646|M.abscessus_ATCC_1997 ----------MVDQSALTLDEG------------------LREAIPMPVE
Mb0849|M.bovis_AF2122/97 ---------MTQDTSATCPLTSTVQDSSPVAGQLGRPIGFRGLAGGCPVS
Rv0826|M.tuberculosis_H37Rv ---------MTQDTSATCPLTSTVQDSSPVAGQLGRPIGFRGLAGGCPVS
MSMEG_5767|M.smegmatis_MC2_155 ---------MTQDTSETCPVTS----------------GSARPAAGCPAA
Mflv_0060|M.gilvum_PYR-GCK LDG-----ADTDALPLGPQSLVWRYFGDNRMYLIG-PRPAVLQNMLAELG
Mvan_0854|M.vanbaalenii_PYR-1 LD---------DALPLGPQSLVWKYFGDNRMYLIG-PRPAVLQNMLAELG
TH_4628|M.thermoresistible__bu ARR-----DTPDALPLGPDSLVWRYFGDNRMPLIG-PRPAVLQNMLAELG
MMAR_0288|M.marinum_M DRP---VDDEIVAQRLGPTSLIWKFYGDVRTQLFGFQRAAGTENCIEQLG
MUL_4835|M.ulcerans_Agy99 DRP---VDDEIVAQRLGPTSLIWKFYGDVRTQLFGFQRAAGTENCIEQLG
MAV_5226|M.avium_104 DGPDWSARDAADAPRLGPDSLIWKFYGDNRTQLFGFQRTAGVENCIEQLA
MAB_4646|M.abscessus_ATCC_1997 DKP------DEPSLRLGADSLVWKFYGDIR-GVLGFQRLAGTENCIEQLG
Mb0849|M.bovis_AF2122/97 PLG-----YESPPLPLGPDSLTWRYFGDWRGMLQG-PWAGSMQNMHPQLG
Rv0826|M.tuberculosis_H37Rv PLG-----YESPPLPLGPDSLTWRYFGDWRGMLQG-PWAGSMQNMHPQLG
MSMEG_5767|M.smegmatis_MC2_155 LGG-----YEAPPEVLGPDSLTWKIFGDWRGLLQG-PWAGSMQNMHPQLG
. **. ** *: :** * : * . :* :*.
Mflv_0060|M.gilvum_PYR-GCK QGVYDHSTFFADTAERLKRTIPPILNTVYGSD-EENAGLQVRDFHHHVKG
Mvan_0854|M.vanbaalenii_PYR-1 QGVYDHSTFFADTAERLKRTIPPIFNTVYGSD-ENNAGLQVRDFHHHVKG
TH_4628|M.thermoresistible__bu QGVLDHSVFFSDTAARVRRSLPPIFMTVYGSD-DENPGRQVRDYHTEIKG
MMAR_0288|M.marinum_M QGVLDHSVVFSDTLGRAKRTGPPLMRTVYSED-PHGWGRTVRDFHKPIKG
MUL_4835|M.ulcerans_Agy99 QGVLDHSVVFSDTLGRAKRTGSPLMRPVYSED-PHGWGRTVRDFHKPIKG
MAV_5226|M.avium_104 QGVLDHSVIFSDTLGRAKRTAPPLMNTVYSDD-PQEWGRKVRDFHKTIKG
MAB_4646|M.abscessus_ATCC_1997 KAVEDHSVIFTDTIGRARRSGPPIMKTIYSAD-PQKWGRMVRDFHKPITG
Mb0849|M.bovis_AF2122/97 AAVEDHSTFFRGRWPRLLRSLYPIGGVVFDGDRAPVTGVQVRDYHITIKG
Rv0826|M.tuberculosis_H37Rv AAVEDHSTFFRERWPRLLRSLYPIGGVVFDGDRAPVTGVQVRDYHITIKG
MSMEG_5767|M.smegmatis_MC2_155 AAVEEHSIFFRERIPRLLRSLYPIGGVVFDGDRAPQTGAQVRDYHIGIKG
.* :** .* * *: *: ::. * * ***:* :.*
Mflv_0060|M.gilvum_PYR-GCK VMPGPDGEEAGRYHALDPETYFWAHATFVEQVYYFADTFVKRLTDAEREQ
Mvan_0854|M.vanbaalenii_PYR-1 EMPGTDG---ARYHALDPETYFWAHATFVEQIYYFADTFVKRLTDAEREQ
TH_4628|M.thermoresistible__bu TMP--DG---QRYHALDPETYFWAHATFVDQVLYFADTFVKRLTRAEKEQ
MMAR_0288|M.marinum_M TIG--DG---SRYHALNPELFYWAHATFVDQILYNTDTFIRRLSRAEKEQ
MUL_4835|M.ulcerans_Agy99 TIG--DG---SRYHALNPELFYWAHATFVDQILYNTDTFIRRLSRAEKEQ
MAV_5226|M.avium_104 TIS--DG---SRYHALNPELFYWAHASFVDQVIYNTDTFIRRLTRAEKEQ
MAB_4646|M.abscessus_ATCC_1997 TIS--DG---TRYHALNPELFYWAHATFVDQVLYITDTFIRRLSYEEKVR
Mb0849|M.bovis_AF2122/97 VDG--AG---RRYHALNPDVFYWAHATFFVGTLHVAERFCGGLTEAQRRQ
Rv0826|M.tuberculosis_H37Rv VDG--AG---RRYHALNPDVFYWAHATFFVGTLHVAERFCGGLTEAQRRQ
MSMEG_5767|M.smegmatis_MC2_155 VDS--QG---RRYSALNPDVFYWAHSTFFMGTILTAERFGGGLTEDQKRQ
* ** **:*: ::***::*. :: * *: :: :
Mflv_0060|M.gilvum_PYR-GCK IWLESKTWYRRYGVSDRVMPATYAEFVQYWDRMMDQVVVAHPTAKYGVGY
Mvan_0854|M.vanbaalenii_PYR-1 IWLESKTWYRRYGVSDRPMPATYAEFEQYWDRMMDQVVVAHPSAKYGVGY
TH_4628|M.thermoresistible__bu IYLESKTWYRRYGVSDRVMPATYDEFERYWDRMLDEIIVAHKTAKYGVGY
MMAR_0288|M.marinum_M IFEESKIWYGLYGVSDRSQPQTYDEFVAYWDGMLDR-FVPHKTVLYGTGY
MUL_4835|M.ulcerans_Agy99 IFEESKIWYGLYGVSDRSQPQTYDEFVAYWDGMLDR-FVPHKTVLYGTGY
MAV_5226|M.avium_104 IFNEGKVWYSLYGVSDRGQPQTYDDFLAYWDEMLDR-FVPHKTVLYGTGY
MAB_4646|M.abscessus_ATCC_1997 IFEESKVWYSLYGVSARNQPQTYDEFVTYMESMFDR-FVPTKTILYATGY
Mb0849|M.bovis_AF2122/97 LFDEHVQWYRMYGMSMRPVPATWEEFQDYWDHMCRNVLENNFAARAVLDL
Rv0826|M.tuberculosis_H37Rv LFDEHVQWYRMYGMSMRPVPATWEEFQDYWDHMCRNVLENNFAARAVLDL
MSMEG_5767|M.smegmatis_MC2_155 LFDEHIVWYRQYGMSMRPVPKTWEEFQEYWDHICRNVLENNYAAREVLDL
:: * ** **:* * * *: :* * : : . . : .
Mflv_0060|M.gilvum_PYR-GCK VTKG-FPKPKAVHPLVWRLVAPVFNPLAAFLTTGGLPPRARMLLGLPWSD
Mvan_0854|M.vanbaalenii_PYR-1 VTKG-FPKPKAVHPLVWRLVAPVFNPLAAFLTTGGLPPRARMLLGLPWTD
TH_4628|M.thermoresistible__bu VTKG-FPCPKGVHPAVWKVISVVFDPVAAFLTTGGLPPRARTLLNLPWSE
MMAR_0288|M.marinum_M LRKG-IPGPRKLPALIWRILSAPLNAYARLVIVGTLPPQMREVCDLDWNA
MUL_4835|M.ulcerans_Agy99 LRKG-IPGPRKLPALIWRILSAPLNAYARLVIVGTLPPQMREVCDLDWNA
MAV_5226|M.avium_104 LRKG-IPGPRWMPRPVWKIVSAPLNAYARLVVVGTLPPQMREVCQLRWDA
MAB_4646|M.abscessus_ATCC_1997 IRQG-LPGPRQIPRPLWKVLSAPLNAFIRTVVVGTLPPQMKDVCRLQWSD
Mb0849|M.bovis_AF2122/97 TELPKPPFAQRVPDWLWAAPRKLLARFFVWLTVGLYDPPVRELMGYRWLR
Rv0826|M.tuberculosis_H37Rv TELPKPPFAQRVPDWLWAAPRKLLARFFVWLTVGLYDPPVRELMGYRWLR
MSMEG_5767|M.smegmatis_MC2_155 STMPKHPSLEWIPDWLWKLNLKILGPFAVWVTVGLYDPPVRELMGYTWSD
* . : :* : : .* * : : *
Mflv_0060|M.gilvum_PYR-GCK KQERRYQRFAAFWRSRPVNWVWDRLPMTVRYSGYAVKGFTRSDMRSDVRA
Mvan_0854|M.vanbaalenii_PYR-1 KQERRYQRFAAIWRSRPVNWIWDRLPMRVRYSGYAVKGYARN--------
TH_4628|M.thermoresistible__bu KQERRYQRFAAFCRSRPVNWVWDRLPMKVRYNKYARRGYARAA-------
MMAR_0288|M.marinum_M KKERRFQRFAALIRG--LNPVLGRLPVRLIYLPWAAQAWTRSGVDPRRLH
MUL_4835|M.ulcerans_Agy99 KKERRFQRSAALIRG--LNPVLGRLPVRLIDLPWAAQARTRSGVDPRRLH
MAV_5226|M.avium_104 KKEKRFQRFAALMRA--LNPLINRLPVRVLYTPWAAQAWSRAGVDPRRLH
MAB_4646|M.abscessus_ATCC_1997 KKERNFRRFAALMRA--LNPVFNRLPVRWLYLPWAAEGWKREGVDPRPLH
Mb0849|M.bovis_AF2122/97 RDEWLHRRFGDIVQL-----VFALVPFRFRKHPRARAGWDRATGRIPADA
Rv0826|M.tuberculosis_H37Rv RDEWLHRRFGDIVRL-----VFALVPFRFRKHPRARAGWDRATGRIPADA
MSMEG_5767|M.smegmatis_MC2_155 RDEKLHRLFGKAVHY-----TFKMLPERRRRHPRARAGWDRAQGRIPADA
:.* .: . : :* * . *
Mflv_0060|M.gilvum_PYR-GCK ----------------------------
Mvan_0854|M.vanbaalenii_PYR-1 ----------------------------
TH_4628|M.thermoresistible__bu ----------------------------
MMAR_0288|M.marinum_M RRAVST----------------------
MUL_4835|M.ulcerans_Agy99 RRAVST----------------------
MAV_5226|M.avium_104 NRAAA-----------------------
MAB_4646|M.abscessus_ATCC_1997 NRVA------------------------
Mb0849|M.bovis_AF2122/97 PLVQTPARNLPPPDERDNPTHYCPKV--
Rv0826|M.tuberculosis_H37Rv PLVQTPARNLPPPDERDNPTHYCPKV--
MSMEG_5767|M.smegmatis_MC2_155 PLVETPARNLPPLDARDSPWHYCPAVTK