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MATELTAGVDFDTGVREALPMPIDRPVDDEIVAQRLGPTSLIWKFYGDVRTQLFGFQRAAGTENCIEQLG QGVLDHSVVFSDTLGRAKRTGPPLMRTVYSEDPHGWGRTVRDFHKPIKGTIGDGSRYHALNPELFYWAHA TFVDQILYNTDTFIRRLSRAEKEQIFEESKIWYGLYGVSDRSQPQTYDEFVAYWDGMLDRFVPHKTVLYG TGYLRKGIPGPRKLPALIWRILSAPLNAYARLVIVGTLPPQMREVCDLDWNAKKERRFQRFAALIRGLNP VLGRLPVRLIYLPWAAQAWTRSGVDPRRLHRRAVST
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_0288 | - | - | 100% (316) | hypothetical protein MMAR_0288 |
M. marinum M | MMAR_2452 | - | 1e-39 | 36.44% (247) | hypothetical protein MMAR_2452 |
M. marinum M | MMAR_4854 | - | 1e-36 | 34.56% (272) | hypothetical protein MMAR_4854 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1672c | - | 1e-40 | 36.84% (247) | hypothetical protein Mb1672c |
M. gilvum PYR-GCK | Mflv_0060 | - | 4e-72 | 48.73% (275) | hypothetical protein Mflv_0060 |
M. tuberculosis H37Rv | Rv1645c | - | 1e-40 | 36.84% (247) | hypothetical protein Rv1645c |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_4646 | - | 1e-129 | 68.30% (306) | hypothetical protein MAB_4646 |
M. avium 104 | MAV_5226 | - | 1e-150 | 78.16% (316) | hypothetical protein MAV_5226 |
M. smegmatis MC2 155 | MSMEG_3781 | - | 2e-39 | 35.27% (292) | hypothetical protein MSMEG_3781 |
M. thermoresistible (build 8) | TH_4628 | - | 1e-79 | 52.22% (270) | PUTATIVE conserved hypothetical protein |
M. ulcerans Agy99 | MUL_4835 | - | 0.0 | 98.42% (316) | hypothetical protein MUL_4835 |
M. vanbaalenii PYR-1 | Mvan_0854 | - | 9e-73 | 49.26% (272) | hypothetical protein Mvan_0854 |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_0288|M.marinum_M --------MATELTAGVDFDTGVREALPMPI-DRP---VDDEIVAQRLGP MUL_4835|M.ulcerans_Agy99 --------MATELTAGVDFDTGVREALPMPI-DRP---VDDEIVAQRLGP MAV_5226|M.avium_104 ---------MTAQRAAWDFDNGVREAVPMPN-DGPDWSARDAADAPRLGP MAB_4646|M.abscessus_ATCC_1997 ----------MVDQSALTLDEGLREAIPMPVEDKP------DEPSLRLGA Mflv_0060|M.gilvum_PYR-GCK ----------------------MTELADKNGHLDG-----ADTDALPLGP Mvan_0854|M.vanbaalenii_PYR-1 MRAVNLVTASLVQSAESVTLLPMTELAQQTEHLD---------DALPLGP TH_4628|M.thermoresistible__bu ----------------------MTELVETPQDARR-----DTPDALPLGP Mb1672c|M.bovis_AF2122/97 ----------------------------MTVASRT--------SADPLGP Rv1645c|M.tuberculosis_H37Rv ----------------------------MTVASRT--------SADPLGP MSMEG_3781|M.smegmatis_MC2_155 -------------------------MATRATSTDT--------ASDPLGL : ** MMAR_0288|M.marinum_M TSLIWKFYGDVRTQLFGFQRAAGTENCIEQLGQGVLDHSVVFSDTLGRAK MUL_4835|M.ulcerans_Agy99 TSLIWKFYGDVRTQLFGFQRAAGTENCIEQLGQGVLDHSVVFSDTLGRAK MAV_5226|M.avium_104 DSLIWKFYGDNRTQLFGFQRTAGVENCIEQLAQGVLDHSVIFSDTLGRAK MAB_4646|M.abscessus_ATCC_1997 DSLVWKFYGDIR-GVLGFQRLAGTENCIEQLGKAVEDHSVIFTDTIGRAR Mflv_0060|M.gilvum_PYR-GCK QSLVWRYFGDNRMYLIG-PRPAVLQNMLAELGQGVYDHSTFFADTAERLK Mvan_0854|M.vanbaalenii_PYR-1 QSLVWKYFGDNRMYLIG-PRPAVLQNMLAELGQGVYDHSTFFADTAERLK TH_4628|M.thermoresistible__bu DSLVWRYFGDNRMPLIG-PRPAVLQNMLAELGQGVLDHSVFFSDTAARVR Mb1672c|M.bovis_AF2122/97 DSLTWKYFGDLRTGMMG-VWIGAIQNMYPELGAGVEEHSILLREPLQRVA Rv1645c|M.tuberculosis_H37Rv DSLTWKYFGDLRTGMMG-VWIGAIQNMYPELGAGVEEHSILLREPLQRVA MSMEG_3781|M.smegmatis_MC2_155 DSLTWKYFGDLRTGMLG-VWIGAIQNMYPELGAGVEEHSILLREPLQRVA ** *:::** * ::* . :* :*. .* :** .: :. * MMAR_0288|M.marinum_M RTGPPLMRTVYSED-PHGWGRTVRDFHKPIKGTIG--DG---SRYHALNP MUL_4835|M.ulcerans_Agy99 RTGSPLMRPVYSED-PHGWGRTVRDFHKPIKGTIG--DG---SRYHALNP MAV_5226|M.avium_104 RTAPPLMNTVYSDD-PQEWGRKVRDFHKTIKGTIS--DG---SRYHALNP MAB_4646|M.abscessus_ATCC_1997 RSGPPIMKTIYSAD-PQKWGRMVRDFHKPITGTIS--DG---TRYHALNP Mflv_0060|M.gilvum_PYR-GCK RTIPPILNTVYGSD-EENAGLQVRDFHHHVKGVMPGPDGEEAGRYHALDP Mvan_0854|M.vanbaalenii_PYR-1 RTIPPIFNTVYGSD-ENNAGLQVRDFHHHVKGEMPGTDG---ARYHALDP TH_4628|M.thermoresistible__bu RSLPPIFMTVYGSD-DENPGRQVRDYHTEIKGTMP--DG---QRYHALDP Mb1672c|M.bovis_AF2122/97 RSVYPIMGVVYDGDRAAQTGQQIKGYHRTIKGVDA--EG---RRYHALNP Rv1645c|M.tuberculosis_H37Rv RSVYPIMGVVYDGDRAAQTGQQIKGYHRTIKGVDA--EG---RRYHALNP MSMEG_3781|M.smegmatis_MC2_155 RSVYPIMGVVYDGDRAPETGAQIKGFHKTIKGVDS--SG---RRYHALNP *: *:: :*. * * ::.:* :.* .* *****:* MMAR_0288|M.marinum_M ELFYWAHATFVDQILYNTDTFIRRLSRAEKEQIFEESKIWYGLYGVSDRS MUL_4835|M.ulcerans_Agy99 ELFYWAHATFVDQILYNTDTFIRRLSRAEKEQIFEESKIWYGLYGVSDRS MAV_5226|M.avium_104 ELFYWAHASFVDQVIYNTDTFIRRLTRAEKEQIFNEGKVWYSLYGVSDRG MAB_4646|M.abscessus_ATCC_1997 ELFYWAHATFVDQVLYITDTFIRRLSYEEKVRIFEESKVWYSLYGVSARN Mflv_0060|M.gilvum_PYR-GCK ETYFWAHATFVEQVYYFADTFVKRLTDAEREQIWLESKTWYRRYGVSDRV Mvan_0854|M.vanbaalenii_PYR-1 ETYFWAHATFVEQIYYFADTFVKRLTDAEREQIWLESKTWYRRYGVSDRP TH_4628|M.thermoresistible__bu ETYFWAHATFVDQVLYFADTFVKRLTRAEKEQIYLESKTWYRRYGVSDRV Mb1672c|M.bovis_AF2122/97 DTFYWAHATFFMLVIKVAEYFCGGLTEAEKHQLFEEHVRWYRMYGMSMRP Rv1645c|M.tuberculosis_H37Rv DTFYWAHATFFMLVIKVAEYFCGGLTEAEKHQLFEEHVRWYRMYGMSMRP MSMEG_3781|M.smegmatis_MC2_155 ETFYWAHATFFMLIIKTAEYFCGGLTEAEKRQLFDEHVQWYRMYGMSMRP : ::****:*. : :: * *: *: ::: * ** **:* * MMAR_0288|M.marinum_M QPQTYDEFVAYWDGMLDR-FVPHKTVLYGTGYLRKGIPGPRKLPALIWRI MUL_4835|M.ulcerans_Agy99 QPQTYDEFVAYWDGMLDR-FVPHKTVLYGTGYLRKGIPGPRKLPALIWRI MAV_5226|M.avium_104 QPQTYDDFLAYWDEMLDR-FVPHKTVLYGTGYLRKGIPGPRWMPRPVWKI MAB_4646|M.abscessus_ATCC_1997 QPQTYDEFVTYMESMFDR-FVPTKTILYATGYIRQGLPGPRQIPRPLWKV Mflv_0060|M.gilvum_PYR-GCK MPATYAEFVQYWDRMMDQVVVAHPTAKYGVGYVTKGFPKPKAVHPLVWRL Mvan_0854|M.vanbaalenii_PYR-1 MPATYAEFEQYWDRMMDQVVVAHPSAKYGVGYVTKGFPKPKAVHPLVWRL TH_4628|M.thermoresistible__bu MPATYDEFERYWDRMLDEIIVAHKTAKYGVGYVTKGFPCPKGVHPAVWKV Mb1672c|M.bovis_AF2122/97 VPKSWEDFQDYWDRVCRD-KLEINQATVDILQMRIPKPRFVLMPTPIWDQ Rv1645c|M.tuberculosis_H37Rv VPKSWEDFQDYWDRVCRD-KLEINQATVDILQMRIPKPRFVLMPTPIWDQ MSMEG_3781|M.smegmatis_MC2_155 VPQTWEEFQDYWDAKCRD-ELEINRATLDIFSIRIPKPWFVLMPTPIWDQ * :: :* * : : : * : :* MMAR_0288|M.marinum_M LSAPLNAYARLVIVGTLPPQMREVCDLDWNAKKERRFQRFAALIRG--LN MUL_4835|M.ulcerans_Agy99 LSAPLNAYARLVIVGTLPPQMREVCDLDWNAKKERRFQRSAALIRG--LN MAV_5226|M.avium_104 VSAPLNAYARLVVVGTLPPQMREVCQLRWDAKKEKRFQRFAALMRA--LN MAB_4646|M.abscessus_ATCC_1997 LSAPLNAFIRTVVVGTLPPQMKDVCRLQWSDKKERNFRRFAALMRA--LN Mflv_0060|M.gilvum_PYR-GCK VAPVFNPLAAFLTTGGLPPRARMLLGLPWSDKQERRYQRFAAFWRSRPVN Mvan_0854|M.vanbaalenii_PYR-1 VAPVFNPLAAFLTTGGLPPRARMLLGLPWTDKQERRYQRFAAIWRSRPVN TH_4628|M.thermoresistible__bu ISVVFDPVAAFLTTGGLPPRARTLLNLPWSEKQERRYQRFAAFCRSRPVN Mb1672c|M.bovis_AF2122/97 LFKPLIAGQRWIAAGLFDPAVREKAGMHWTPGDEVLLRVFGKVVEL---- Rv1645c|M.tuberculosis_H37Rv LFKPLIAGQRWIAAGLFDPAVREKAGMHWTPGDEVLLRVFGKVVEL---- MSMEG_3781|M.smegmatis_MC2_155 LFKPLVGAQRWIAAGLFDPVVREKAGMRWTPGDEVLLRIFGKAVEL---- : : : .* : * : : * .* : . . MMAR_0288|M.marinum_M PVLGRLPVRLIYLPWAAQAWTRSGVDPRRLHRRAVST------------- MUL_4835|M.ulcerans_Agy99 PVLGRLPVRLIDLPWAAQARTRSGVDPRRLHRRAVST------------- MAV_5226|M.avium_104 PLINRLPVRVLYTPWAAQAWSRAGVDPRRLHNRAAA-------------- MAB_4646|M.abscessus_ATCC_1997 PVFNRLPVRWLYLPWAAEGWKREGVDPRPLHNRVA--------------- Mflv_0060|M.gilvum_PYR-GCK WVWDRLPMTVRYSGYAVKGFTRSDMRSDVRA------------------- Mvan_0854|M.vanbaalenii_PYR-1 WIWDRLPMRVRYSGYAVKGYARN--------------------------- TH_4628|M.thermoresistible__bu WVWDRLPMKVRYNKYARRGYARAA-------------------------- Mb1672c|M.bovis_AF2122/97 -AFLAVPDEIRLHPRALAAYRRAAGRTRHDAPLVQAPGFMAPPRDRQGLP Rv1645c|M.tuberculosis_H37Rv -AFLAVPDEIRLHPRALAAYRRAAGRTRHDAPLVQAPGFMAPPRDRQGLP MSMEG_3781|M.smegmatis_MC2_155 -AFLAVPDEIRLHPRAVSAYRRAKGRIPADAPLVEAPGFTAPPKDRRGLP :* * . * MMAR_0288|M.marinum_M -------------------------------------------------- MUL_4835|M.ulcerans_Agy99 -------------------------------------------------- MAV_5226|M.avium_104 -------------------------------------------------- MAB_4646|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_0060|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0854|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_4628|M.thermoresistible__bu -------------------------------------------------- Mb1672c|M.bovis_AF2122/97 MHYFPPRSHRFTRSALDPAKALMERAGALVHSTLSLAGVRPAR--GPSRA Rv1645c|M.tuberculosis_H37Rv MHYFPPRSHRFTRSALDPAKALMERAGALVHSTLSLAGVRPAR--GPSRA MSMEG_3781|M.smegmatis_MC2_155 MHYLPQR------------RSLLDRAGALVHSTLSLPALRPAKKSSPRRS MMAR_0288|M.marinum_M -- MUL_4835|M.ulcerans_Agy99 -- MAV_5226|M.avium_104 -- MAB_4646|M.abscessus_ATCC_1997 -- Mflv_0060|M.gilvum_PYR-GCK -- Mvan_0854|M.vanbaalenii_PYR-1 -- TH_4628|M.thermoresistible__bu -- Mb1672c|M.bovis_AF2122/97 A- Rv1645c|M.tuberculosis_H37Rv A- MSMEG_3781|M.smegmatis_MC2_155 AA