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VTQDTSATCPLTSTVQDSSPVAGQLGRPIGFRGLAGGCPVSPLGYESPPLPLGPDSLTWRYFGDWRGMLQ GPWAGSMQNMHPQLGAAVEDHSTFFRERWPRLLRSLYPIGGVVFDGDRAPVTGVQVRDYHITIKGVDGAG RRYHALNPDVFYWAHATFFVGTLHVAERFCGGLTEAQRRQLFDEHVQWYRMYGMSMRPVPATWEEFQDYW DHMCRNVLENNFAARAVLDLTELPKPPFAQRVPDWLWAAPRKLLARFFVWLTVGLYDPPVRELMGYRWLR RDEWLHRRFGDIVRLVFALVPFRFRKHPRARAGWDRATGRIPADAPLVQTPARNLPPPDERDNPTHYCPK V
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0826 | - | - | 100% (351) | hypothetical protein Rv0826 |
| M. tuberculosis H37Rv | Rv1645c | - | 6e-98 | 57.53% (299) | hypothetical protein Rv1645c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0849 | - | 0.0 | 99.43% (351) | hypothetical protein Mb0849 |
| M. gilvum PYR-GCK | Mflv_1670 | - | 1e-140 | 66.67% (351) | hypothetical protein Mflv_1670 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0757 | - | 1e-150 | 75.56% (315) | hypothetical protein MAB_0757 |
| M. marinum M | MMAR_4854 | - | 0.0 | 86.65% (352) | hypothetical protein MMAR_4854 |
| M. avium 104 | MAV_0774 | - | 0.0 | 82.63% (357) | hypothetical protein MAV_0774 |
| M. smegmatis MC2 155 | MSMEG_5767 | - | 1e-153 | 71.79% (351) | hypothetical protein MSMEG_5767 |
| M. thermoresistible (build 8) | TH_1574 | - | 1e-144 | 75.32% (312) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0447 | - | 0.0 | 86.36% (352) | hypothetical protein MUL_0447 |
| M. vanbaalenii PYR-1 | Mvan_5083 | - | 1e-144 | 68.47% (352) | hypothetical protein Mvan_5083 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0826|M.tuberculosis_H37Rv MTQDTSATCPLTSTVQDSSP----VAGQLGRPIGF-RGLAGGCPVSPLGY
Mb0849|M.bovis_AF2122/97 MTQDTSATCPLTSTVQDSSP----VAGQLGRPIGF-RGLAGGCPVSPLGY
MMAR_4854|M.marinum_M MTQDTSAACPLTSAEPKSSTN---SAGQVAAPGDS-QPAATGCPVSPLGY
MUL_0447|M.ulcerans_Agy99 MTQDTSAACPLTSAEPKSSTN---SAGQVAAPGDS-QPAATGCPVSPLGY
MAV_0774|M.avium_104 MTQDTSASRPLTSDVTGSDAAGRTEQSISARPADAGAALAVGCPVSPLGY
MAB_0757|M.abscessus_ATCC_1997 MVNDMSELAKVQPAAESG-------------------AFVSGCPVSHGTG
MSMEG_5767|M.smegmatis_MC2_155 MTQDTSETCPVTSGSARP---------------------AAGCPAALGGY
TH_1574|M.thermoresistible__bu --------------------------------------------VSAGGY
Mflv_1670|M.gilvum_PYR-GCK MTQDTSAAGPVTSDSGEASG-----------------AVAAGCPISGGGY
Mvan_5083|M.vanbaalenii_PYR-1 MTQDTSEADPLTSGSAADSV-----------------PVAAGCPVTSGGY
:
Rv0826|M.tuberculosis_H37Rv ESPPLPLGPDSLTWRYFGDWRGMLQGPWAGSMQNMHPQLGAAVEDHSTFF
Mb0849|M.bovis_AF2122/97 ESPPLPLGPDSLTWRYFGDWRGMLQGPWAGSMQNMHPQLGAAVEDHSTFF
MMAR_4854|M.marinum_M EAPPIPLGPDSLTWRYFGDWRGMLQGPWAGSMQNMHPQLGAAVEDHSTFF
MUL_0447|M.ulcerans_Agy99 EAPPIPLGPDSLTWRYFGDWRGMLQGPWAGSMQNMHPQLGAAVEDHSTFF
MAV_0774|M.avium_104 EAPPAPLGPDSLTWKYFGDWRGMLQGPWAGSMQNMHPQLGAAVLDHSTFF
MAB_0757|M.abscessus_ATCC_1997 KSMPVPLGPESLTWKYFGDWRGMLQGPYAGSMQNMHPQLGAAVEQHSQFF
MSMEG_5767|M.smegmatis_MC2_155 EAPPEVLGPDSLTWKIFGDWRGLLQGPWAGSMQNMHPQLGAAVEEHSIFF
TH_1574|M.thermoresistible__bu DAPPEVLGPDSLTWKIFGDWRGLLQGPWAGSMQNMHPQLGAAVKDHSIFF
Mflv_1670|M.gilvum_PYR-GCK DALPEPLGPDSLTWKYFGQWTGLFQGTWAGSMQNMHPQLGAAVKDHSIFF
Mvan_5083|M.vanbaalenii_PYR-1 DSVPQPLGPDSLTWKYFGQWTGLFQGPWAGSMQNMHPQLGAAVKDHSIFF
.: * ***:****: **:* *::**.:*************** :** **
Rv0826|M.tuberculosis_H37Rv RERWPRLLRSLYPIGGVVFDGDRAPVTGVQVRDYHITIKGVDGAGRRYHA
Mb0849|M.bovis_AF2122/97 RGRWPRLLRSLYPIGGVVFDGDRAPVTGVQVRDYHITIKGVDGAGRRYHA
MMAR_4854|M.marinum_M RERWPRLLRSLYPIGGVVFDGDRAPVTGAEVRDYHVNIKGVDAAGRRYHA
MUL_0447|M.ulcerans_Agy99 RERWPRLLRSLYPIGGVVFDGDRAPVTGAEVRDYHVNIKGVDAAGRRYHA
MAV_0774|M.avium_104 RERWPRLLRSLYPIGGVVFDGDRAPITGAEVRDYHTDIKGVDEQGRRYHA
MAB_0757|M.abscessus_ATCC_1997 RERWQRLLRSLYPIGGVVFDGDRAPMTGAEVRDYHVNIKGVDDQGRRYSA
MSMEG_5767|M.smegmatis_MC2_155 RERIPRLLRSLYPIGGVVFDGDRAPQTGAQVRDYHIGIKGVDSQGRRYSA
TH_1574|M.thermoresistible__bu TERIPRLLRSLYPIGGVVFDGDRAPRTGAEVRDYHIGIKGVDEQGRRYSA
Mflv_1670|M.gilvum_PYR-GCK MERIPRLLRSIYPIGGVVFDGDRAPKTGAQVRDYHIGLNGVDDQGRRYSA
Mvan_5083|M.vanbaalenii_PYR-1 MERMPRLLRSIYPIGGVVFDGDRAPKTGAQVRDYHIGLTGVDDQGRRYSA
* *****:************** **.:***** :.*** **** *
Rv0826|M.tuberculosis_H37Rv LNPDVFYWAHATFFVGTLHVAERFCGGLTEAQRRQLFDEHVQWYRMYGMS
Mb0849|M.bovis_AF2122/97 LNPDVFYWAHATFFVGTLHVAERFCGGLTEAQRRQLFDEHVQWYRMYGMS
MMAR_4854|M.marinum_M LNPDVFYWAHATFFVGTIHVAERFCGGLTEAQKRQLFDEHVQWYRMYGMS
MUL_0447|M.ulcerans_Agy99 LNPDVFYWAHATFFVGTIHVAERFCGGLTEAQKRQLFDEHVQWYRMYGMS
MAV_0774|M.avium_104 LNPDVFYWAHSTFFVGTIHVAERFCGGITEEQKRQLFDEHVQWYRMYGMS
MAB_0757|M.abscessus_ATCC_1997 LNPDVFYWAHATFFMGTIIVAERFCGGITEAEKRQLFDEHITWYQMYGMS
MSMEG_5767|M.smegmatis_MC2_155 LNPDVFYWAHSTFFMGTILTAERFGGGLTEDQKRQLFDEHIVWYRQYGMS
TH_1574|M.thermoresistible__bu LNPDVFYWAHSTFFMGTILTAERFGDGLTEDQKRRLFDEHITWYRMYGMS
Mflv_1670|M.gilvum_PYR-GCK LNPDVFYWAHATFFKSTLLAAEKFGGGLTEADKRQLFDEHVTWYRMYGMS
Mvan_5083|M.vanbaalenii_PYR-1 LNPDVFYWAHATFFKSTLLAAERFHGGLTEDQRRQLFDEHVTWYRMYGMS
**********:*** .*: .**:* .*:** ::*:*****: **: ****
Rv0826|M.tuberculosis_H37Rv MRPVPATWEEFQDYWDHMCRNVLENNFAARAVLDLTELPKPPFAQRVPDW
Mb0849|M.bovis_AF2122/97 MRPVPATWEEFQDYWDHMCRNVLENNFAARAVLDLTELPKPPFAQRVPDW
MMAR_4854|M.marinum_M MRPVPASWEEFQVYWDHMCCNVLENNFAARAVLDLTELPKPPFAQRVPDR
MUL_0447|M.ulcerans_Agy99 MRPVPASWEEFQVYWDHMCCNVLENNFAARAVLDLTELPKPPFAQRVPDR
MAV_0774|M.avium_104 MRPVPKSWEEFQEYWDHMCRNVLENNEAARAVLDLTELPRPPFAQRIPNR
MAB_0757|M.abscessus_ATCC_1997 MRPVPKSWEEFQEYWDHMCTNVLEDNKATRDVLDLTTLAVPPFAPWIPKW
MSMEG_5767|M.smegmatis_MC2_155 MRPVPKTWEEFQEYWDHICRNVLENNYAAREVLDLSTMPKHPSLEWIPDW
TH_1574|M.thermoresistible__bu MRPVPGSWEEFQQYWDHMCRNVLENTWAARQVLDLSTMPKHPSLQWIPDW
Mflv_1670|M.gilvum_PYR-GCK MRPVPKTWEEFQEYWDHMCTDVLENNWAAREVMDLSTMPKHPSLEWIPDP
Mvan_5083|M.vanbaalenii_PYR-1 MRPVPKTWEDFQEYWDHMCTNVLENNWATREVLDLSTMPKHPSLEWVPDW
***** :**:** ****:* :***:. *:* *:**: :. * :*.
Rv0826|M.tuberculosis_H37Rv LWAAPRKLLARFFVWLTVGLYDPPVRELMGYRWLRRDEWLHRRFGDIVRL
Mb0849|M.bovis_AF2122/97 LWAAPRKLLARFFVWLTVGLYDPPVRELMGYRWLRRDEWLHRRFGDIVQL
MMAR_4854|M.marinum_M LWALQRKLLAPFFVWVTVGLYDPPVRTLMGYQWSRRDEWLHRRFGDLVRL
MUL_0447|M.ulcerans_Agy99 LWALQRKLLVPFFVWVTVGLYDPPVRTLMGYQWSRRDEWLHRRFGDLVRL
MAV_0774|M.avium_104 LWAAQRKLLAPFFVWVTVGLYDPPVRELMGYRWSARDEWLHRRFGDLVRI
MAB_0757|M.abscessus_ATCC_1997 LWALQRRMLSPFFVWFTVGLYDPPVRKRLGYTWSDRDEWLHRSFGRLVNV
MSMEG_5767|M.smegmatis_MC2_155 LWKLNLKILGPFAVWVTVGLYDPPVRELMGYTWSDRDEKLHRLFGKAVHY
TH_1574|M.thermoresistible__bu LWKLQLKVLGPFAVWVTVGLYDPPVRELMGYTWSERDERLHRLFGRAVNL
Mflv_1670|M.gilvum_PYR-GCK LWKLNLAVMQRFLTFMTVALYDPPVRELMGYTWSPRQEFLHRRFCDVVTL
Mvan_5083|M.vanbaalenii_PYR-1 LWKQNLKVMQRFLLFMTVGLYDPPIRELMGFTWSPRQEWLHRRVGNMLHL
** :: * :.**.*****:* :*: * *:* *** . :
Rv0826|M.tuberculosis_H37Rv VFALVPFRFRKHPRARAGWDRATGRIPADAPLVQTPARNLPPPDERDNPT
Mb0849|M.bovis_AF2122/97 VFALVPFRFRKHPRARAGWDRATGRIPADAPLVQTPARNLPPPDERDNPT
MMAR_4854|M.marinum_M IFALVPSRMRKHPRGRAGWDRAKGRIPADAPLVQTPARNLPPLDERDNPM
MUL_0447|M.ulcerans_Agy99 IFALVPRRMRKHPRGRAGWDRAMGRIPADAPLVQTPARNLPPLDERDNPM
MAV_0774|M.avium_104 VFALVPSRFRKHPRARAGLDRASGRIPLDAPLVQTPARNLPPEDERGNPK
MAB_0757|M.abscessus_ATCC_1997 VFRFVPERFRRHPRARAGWDRALGRIPADAPLPQTPDRNLPPLDTWGSPN
MSMEG_5767|M.smegmatis_MC2_155 TFKMLPERRRRHPRARAGWDRAQGRIPADAPLVETPARNLPPLDARDSPW
TH_1574|M.thermoresistible__bu AFKLLPKRRRMHPRARAGWDRATGRIPADAPLVHTPARNLPPVEHRGKPI
Mflv_1670|M.gilvum_PYR-GCK ATKVLPKRWLMHPRKRSAWDRATGRLPADSALVETPARNLPPLEYRDNPH
Mvan_5083|M.vanbaalenii_PYR-1 ATRLLPDRVTMHPRKRSAMDRAFGRLPADAPLVETPARNLPPVEYRDNPH
.:* * *** *:. *** **:* *:.* .** ***** : ..*
Rv0826|M.tuberculosis_H37Rv HYCPKV--
Mb0849|M.bovis_AF2122/97 HYCPKV--
MMAR_4854|M.marinum_M HYCPEV--
MUL_0447|M.ulcerans_Agy99 HYCPEV--
MAV_0774|M.avium_104 HYCPMVS-
MAB_0757|M.abscessus_ATCC_1997 HYNPKVS-
MSMEG_5767|M.smegmatis_MC2_155 HYCPAVTK
TH_1574|M.thermoresistible__bu HYCPDV--
Mflv_1670|M.gilvum_PYR-GCK YYSPKV--
Mvan_5083|M.vanbaalenii_PYR-1 YYSPKV--
:* * *