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ATELTAGVDFDTGVREALPMPIDRPVDDEIVAQRLGPTSLIWKFYGDVRTQLFGFQRAAGTENCIEQLGQ GVLDHSVVFSDTLGRAKRTGSPLMRPVYSEDPHGWGRTVRDFHKPIKGTIGDGSRYHALNPELFYWAHAT FVDQILYNTDTFIRRLSRAEKEQIFEESKIWYGLYGVSDRSQPQTYDEFVAYWDGMLDRFVPHKTVLYGT GYLRKGIPGPRKLPALIWRILSAPLNAYARLVIVGTLPPQMREVCDLDWNAKKERRFQRSAALIRGLNPV LGRLPVRLIDLPWAAQARTRSGVDPRRLHRRAVST*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4835 | - | - | 100% (316) | hypothetical protein MUL_4835 |
| M. ulcerans Agy99 | MUL_1631 | - | 1e-38 | 34.84% (287) | hypothetical protein MUL_1631 |
| M. ulcerans Agy99 | MUL_0447 | - | 7e-35 | 35.77% (246) | hypothetical protein MUL_0447 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1672c | - | 2e-40 | 37.97% (237) | hypothetical protein Mb1672c |
| M. gilvum PYR-GCK | Mflv_0060 | - | 6e-68 | 47.27% (275) | hypothetical protein Mflv_0060 |
| M. tuberculosis H37Rv | Rv1645c | - | 2e-40 | 37.97% (237) | hypothetical protein Rv1645c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4646 | - | 1e-124 | 66.67% (306) | hypothetical protein MAB_4646 |
| M. marinum M | MMAR_0288 | - | 0.0 | 98.42% (316) | hypothetical protein MMAR_0288 |
| M. avium 104 | MAV_5226 | - | 1e-145 | 76.58% (316) | hypothetical protein MAV_5226 |
| M. smegmatis MC2 155 | MSMEG_3781 | - | 1e-39 | 35.27% (292) | hypothetical protein MSMEG_3781 |
| M. thermoresistible (build 8) | TH_4628 | - | 2e-75 | 52.53% (257) | PUTATIVE conserved hypothetical protein |
| M. vanbaalenii PYR-1 | Mvan_0854 | - | 1e-68 | 47.79% (272) | hypothetical protein Mvan_0854 |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_4835|M.ulcerans_Agy99 --------MATELTAGVDFDTGVREALPMPI-DRP---VDDEIVAQRLGP
MMAR_0288|M.marinum_M --------MATELTAGVDFDTGVREALPMPI-DRP---VDDEIVAQRLGP
MAV_5226|M.avium_104 ---------MTAQRAAWDFDNGVREAVPMPN-DGPDWSARDAADAPRLGP
MAB_4646|M.abscessus_ATCC_1997 ----------MVDQSALTLDEGLREAIPMPVEDKP------DEPSLRLGA
Mflv_0060|M.gilvum_PYR-GCK ----------------------MTELADKNGHLDG-----ADTDALPLGP
Mvan_0854|M.vanbaalenii_PYR-1 MRAVNLVTASLVQSAESVTLLPMTELAQQTEHLD---------DALPLGP
TH_4628|M.thermoresistible__bu ----------------------MTELVETPQDARR-----DTPDALPLGP
Mb1672c|M.bovis_AF2122/97 ----------------------------MTVASRT--------SADPLGP
Rv1645c|M.tuberculosis_H37Rv ----------------------------MTVASRT--------SADPLGP
MSMEG_3781|M.smegmatis_MC2_155 -------------------------MATRATSTDT--------ASDPLGL
: **
MUL_4835|M.ulcerans_Agy99 TSLIWKFYGDVRTQLFGFQRAAGTENCIEQLGQGVLDHSVVFSDTLGRAK
MMAR_0288|M.marinum_M TSLIWKFYGDVRTQLFGFQRAAGTENCIEQLGQGVLDHSVVFSDTLGRAK
MAV_5226|M.avium_104 DSLIWKFYGDNRTQLFGFQRTAGVENCIEQLAQGVLDHSVIFSDTLGRAK
MAB_4646|M.abscessus_ATCC_1997 DSLVWKFYGDIR-GVLGFQRLAGTENCIEQLGKAVEDHSVIFTDTIGRAR
Mflv_0060|M.gilvum_PYR-GCK QSLVWRYFGDNRMYLIG-PRPAVLQNMLAELGQGVYDHSTFFADTAERLK
Mvan_0854|M.vanbaalenii_PYR-1 QSLVWKYFGDNRMYLIG-PRPAVLQNMLAELGQGVYDHSTFFADTAERLK
TH_4628|M.thermoresistible__bu DSLVWRYFGDNRMPLIG-PRPAVLQNMLAELGQGVLDHSVFFSDTAARVR
Mb1672c|M.bovis_AF2122/97 DSLTWKYFGDLRTGMMG-VWIGAIQNMYPELGAGVEEHSILLREPLQRVA
Rv1645c|M.tuberculosis_H37Rv DSLTWKYFGDLRTGMMG-VWIGAIQNMYPELGAGVEEHSILLREPLQRVA
MSMEG_3781|M.smegmatis_MC2_155 DSLTWKYFGDLRTGMLG-VWIGAIQNMYPELGAGVEEHSILLREPLQRVA
** *:::** * ::* . :* :*. .* :** .: :. *
MUL_4835|M.ulcerans_Agy99 RTGSPLMRPVYSED-PHGWGRTVRDFHKPIKGTIG--DG---SRYHALNP
MMAR_0288|M.marinum_M RTGPPLMRTVYSED-PHGWGRTVRDFHKPIKGTIG--DG---SRYHALNP
MAV_5226|M.avium_104 RTAPPLMNTVYSDD-PQEWGRKVRDFHKTIKGTIS--DG---SRYHALNP
MAB_4646|M.abscessus_ATCC_1997 RSGPPIMKTIYSAD-PQKWGRMVRDFHKPITGTIS--DG---TRYHALNP
Mflv_0060|M.gilvum_PYR-GCK RTIPPILNTVYGSD-EENAGLQVRDFHHHVKGVMPGPDGEEAGRYHALDP
Mvan_0854|M.vanbaalenii_PYR-1 RTIPPIFNTVYGSD-ENNAGLQVRDFHHHVKGEMPGTDG---ARYHALDP
TH_4628|M.thermoresistible__bu RSLPPIFMTVYGSD-DENPGRQVRDYHTEIKGTMP--DG---QRYHALDP
Mb1672c|M.bovis_AF2122/97 RSVYPIMGVVYDGDRAAQTGQQIKGYHRTIKGVDA--EG---RRYHALNP
Rv1645c|M.tuberculosis_H37Rv RSVYPIMGVVYDGDRAAQTGQQIKGYHRTIKGVDA--EG---RRYHALNP
MSMEG_3781|M.smegmatis_MC2_155 RSVYPIMGVVYDGDRAPETGAQIKGFHKTIKGVDS--SG---RRYHALNP
*: *:: :*. * * ::.:* :.* .* *****:*
MUL_4835|M.ulcerans_Agy99 ELFYWAHATFVDQILYNTDTFIRRLSRAEKEQIFEESKIWYGLYGVSDRS
MMAR_0288|M.marinum_M ELFYWAHATFVDQILYNTDTFIRRLSRAEKEQIFEESKIWYGLYGVSDRS
MAV_5226|M.avium_104 ELFYWAHASFVDQVIYNTDTFIRRLTRAEKEQIFNEGKVWYSLYGVSDRG
MAB_4646|M.abscessus_ATCC_1997 ELFYWAHATFVDQVLYITDTFIRRLSYEEKVRIFEESKVWYSLYGVSARN
Mflv_0060|M.gilvum_PYR-GCK ETYFWAHATFVEQVYYFADTFVKRLTDAEREQIWLESKTWYRRYGVSDRV
Mvan_0854|M.vanbaalenii_PYR-1 ETYFWAHATFVEQIYYFADTFVKRLTDAEREQIWLESKTWYRRYGVSDRP
TH_4628|M.thermoresistible__bu ETYFWAHATFVDQVLYFADTFVKRLTRAEKEQIYLESKTWYRRYGVSDRV
Mb1672c|M.bovis_AF2122/97 DTFYWAHATFFMLVIKVAEYFCGGLTEAEKHQLFEEHVRWYRMYGMSMRP
Rv1645c|M.tuberculosis_H37Rv DTFYWAHATFFMLVIKVAEYFCGGLTEAEKHQLFEEHVRWYRMYGMSMRP
MSMEG_3781|M.smegmatis_MC2_155 ETFYWAHATFFMLIIKTAEYFCGGLTEAEKRQLFDEHVQWYRMYGMSMRP
: ::****:*. : :: * *: *: ::: * ** **:* *
MUL_4835|M.ulcerans_Agy99 QPQTYDEFVAYWDGMLDR-FVPHKTVLYGTGYLRKGIPGPRKLPALIWRI
MMAR_0288|M.marinum_M QPQTYDEFVAYWDGMLDR-FVPHKTVLYGTGYLRKGIPGPRKLPALIWRI
MAV_5226|M.avium_104 QPQTYDDFLAYWDEMLDR-FVPHKTVLYGTGYLRKGIPGPRWMPRPVWKI
MAB_4646|M.abscessus_ATCC_1997 QPQTYDEFVTYMESMFDR-FVPTKTILYATGYIRQGLPGPRQIPRPLWKV
Mflv_0060|M.gilvum_PYR-GCK MPATYAEFVQYWDRMMDQVVVAHPTAKYGVGYVTKGFPKPKAVHPLVWRL
Mvan_0854|M.vanbaalenii_PYR-1 MPATYAEFEQYWDRMMDQVVVAHPSAKYGVGYVTKGFPKPKAVHPLVWRL
TH_4628|M.thermoresistible__bu MPATYDEFERYWDRMLDEIIVAHKTAKYGVGYVTKGFPCPKGVHPAVWKV
Mb1672c|M.bovis_AF2122/97 VPKSWEDFQDYWDRVCRD-KLEINQATVDILQMRIPKPRFVLMPTPIWDQ
Rv1645c|M.tuberculosis_H37Rv VPKSWEDFQDYWDRVCRD-KLEINQATVDILQMRIPKPRFVLMPTPIWDQ
MSMEG_3781|M.smegmatis_MC2_155 VPQTWEEFQDYWDAKCRD-ELEINRATLDIFSIRIPKPWFVLMPTPIWDQ
* :: :* * : : : * : :*
MUL_4835|M.ulcerans_Agy99 LSAPLNAYARLVIVGTLPPQMREVCDLDWNAKKERRFQRSAALIRG--LN
MMAR_0288|M.marinum_M LSAPLNAYARLVIVGTLPPQMREVCDLDWNAKKERRFQRFAALIRG--LN
MAV_5226|M.avium_104 VSAPLNAYARLVVVGTLPPQMREVCQLRWDAKKEKRFQRFAALMRA--LN
MAB_4646|M.abscessus_ATCC_1997 LSAPLNAFIRTVVVGTLPPQMKDVCRLQWSDKKERNFRRFAALMRA--LN
Mflv_0060|M.gilvum_PYR-GCK VAPVFNPLAAFLTTGGLPPRARMLLGLPWSDKQERRYQRFAAFWRSRPVN
Mvan_0854|M.vanbaalenii_PYR-1 VAPVFNPLAAFLTTGGLPPRARMLLGLPWTDKQERRYQRFAAIWRSRPVN
TH_4628|M.thermoresistible__bu ISVVFDPVAAFLTTGGLPPRARTLLNLPWSEKQERRYQRFAAFCRSRPVN
Mb1672c|M.bovis_AF2122/97 LFKPLIAGQRWIAAGLFDPAVREKAGMHWTPGDEVLLRVFGKVVEL----
Rv1645c|M.tuberculosis_H37Rv LFKPLIAGQRWIAAGLFDPAVREKAGMHWTPGDEVLLRVFGKVVEL----
MSMEG_3781|M.smegmatis_MC2_155 LFKPLVGAQRWIAAGLFDPVVREKAGMRWTPGDEVLLRIFGKAVEL----
: : : .* : * : : * .* : . .
MUL_4835|M.ulcerans_Agy99 PVLGRLPVRLIDLPWAAQARTRSGVDPRRLHRRAVST-------------
MMAR_0288|M.marinum_M PVLGRLPVRLIYLPWAAQAWTRSGVDPRRLHRRAVST-------------
MAV_5226|M.avium_104 PLINRLPVRVLYTPWAAQAWSRAGVDPRRLHNRAAA--------------
MAB_4646|M.abscessus_ATCC_1997 PVFNRLPVRWLYLPWAAEGWKREGVDPRPLHNRVA---------------
Mflv_0060|M.gilvum_PYR-GCK WVWDRLPMTVRYSGYAVKGFTRSDMRSDVRA-------------------
Mvan_0854|M.vanbaalenii_PYR-1 WIWDRLPMRVRYSGYAVKGYARN---------------------------
TH_4628|M.thermoresistible__bu WVWDRLPMKVRYNKYARRGYARAA--------------------------
Mb1672c|M.bovis_AF2122/97 -AFLAVPDEIRLHPRALAAYRRAAGRTRHDAPLVQAPGFMAPPRDRQGLP
Rv1645c|M.tuberculosis_H37Rv -AFLAVPDEIRLHPRALAAYRRAAGRTRHDAPLVQAPGFMAPPRDRQGLP
MSMEG_3781|M.smegmatis_MC2_155 -AFLAVPDEIRLHPRAVSAYRRAKGRIPADAPLVEAPGFTAPPKDRRGLP
:* * . *
MUL_4835|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0288|M.marinum_M --------------------------------------------------
MAV_5226|M.avium_104 --------------------------------------------------
MAB_4646|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0060|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0854|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4628|M.thermoresistible__bu --------------------------------------------------
Mb1672c|M.bovis_AF2122/97 MHYFPPRSHRFTRSALDPAKALMERAGALVHSTLSLAGVRPAR--GPSRA
Rv1645c|M.tuberculosis_H37Rv MHYFPPRSHRFTRSALDPAKALMERAGALVHSTLSLAGVRPAR--GPSRA
MSMEG_3781|M.smegmatis_MC2_155 MHYLPQR------------RSLLDRAGALVHSTLSLPALRPAKKSSPRRS
MUL_4835|M.ulcerans_Agy99 --
MMAR_0288|M.marinum_M --
MAV_5226|M.avium_104 --
MAB_4646|M.abscessus_ATCC_1997 --
Mflv_0060|M.gilvum_PYR-GCK --
Mvan_0854|M.vanbaalenii_PYR-1 --
TH_4628|M.thermoresistible__bu --
Mb1672c|M.bovis_AF2122/97 A-
Rv1645c|M.tuberculosis_H37Rv A-
MSMEG_3781|M.smegmatis_MC2_155 AA