For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_4605 | - | - | 100% (480) | aldehyde dehydrogenase |
M. thermoresistible (build 8) | TH_3080 | - | e-100 | 42.92% (473) | PUTATIVE aldehyde dehydrogenase |
M. thermoresistible (build 8) | TH_3892 | - | 7e-97 | 43.51% (478) | PUTATIVE aldehyde dehydrogenase NAD dependent AldA_2 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0791 | aldA | 2e-90 | 40.39% (463) | aldehyde dehydrogenase NAD dependant AldA |
M. gilvum PYR-GCK | Mflv_1797 | - | 0.0 | 81.01% (474) | aldehyde dehydrogenase |
M. tuberculosis H37Rv | Rv0223c | - | 7e-93 | 40.00% (475) | aldehyde dehydrogenase |
M. leprae Br4923 | MLBr_02573 | gabD1 | 4e-45 | 28.88% (464) | succinic semialdehyde dehydrogenase |
M. abscessus ATCC 19977 | MAB_4484 | - | 1e-100 | 42.77% (477) | aldehyde dehydrogenase |
M. marinum M | MMAR_4928 | aldA | 4e-95 | 42.79% (458) | NAD-dependent aldehyde dehydrogenase, AldA |
M. avium 104 | MAV_5202 | - | 0.0 | 78.90% (474) | aldehyde dehydrogenase |
M. smegmatis MC2 155 | MSMEG_0455 | - | 0.0 | 81.61% (473) | aldehyde dehydrogenase |
M. ulcerans Agy99 | MUL_0477 | aldA | 5e-94 | 42.36% (458) | NAD-dependent aldehyde dehydrogenase, AldA |
M. vanbaalenii PYR-1 | Mvan_4953 | - | 0.0 | 79.11% (474) | aldehyde dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_4928|M.marinum_M -MALLADGVSSLFIDGKRCE-GAAGTFATVNPATEETLGVAADADAGDMD MUL_0477|M.ulcerans_Agy99 -MALLADGVSSLFIDGKRCE-GAAGTFATVNPATEETLGVAADAVAGDMD Mb0791|M.bovis_AF2122/97 -MALWGDGISALLIDGKLSD-GRAGTFPTVNPATEEVLGVAADADAEDMG Mflv_1797|M.gilvum_PYR-GCK -----MREYLKHYIDGQWVDPVRPNALDVDNPATEEVSGKIALGSSADVD Mvan_4953|M.vanbaalenii_PYR-1 -----MREYLKHYIDGRWVDPVRPNALEVDNPTTEEISGRIALGSSADVD MSMEG_0455|M.smegmatis_MC2_155 -----MREYLKFYIDGRWVDPVEPRTLDVDNPTTEQVAGRIAIGAAADVD TH_4605|M.thermoresistible__bu VEDEGMREYLKFYIDGAWVDPVDLKTLDVDDPATEEVSGRIAIGSATDVD MAV_5202|M.avium_104 -----MREYLKFYIDGQWVDPVRPNTFDVENPATEQVCGKISLGSAADVD Rv0223c|M.tuberculosis_H37Rv -MSDSATEYDKLFIGGKWTKPSTSDVIEVRCPATGEYVGKVPMAAAADVD MAB_4484|M.abscessus_ATCC_1997 -----MTNYDKLFIGGVWTEPATDQVIEVISPATGQKVGQCPLASPADVD MLBr_02573|M.leprae_Br4923 ------------------------MSIATINPATGETVKTFTPTTQDEVE : . *:* : . :: MMAR_4928|M.marinum_M RAIEAARRAFDDTDWSRNT-ELRVRCVRQLRDAMREHIEELRALTISEVG MUL_0477|M.ulcerans_Agy99 RAIEAARRAFDDTDWSRNT-ELRVRCVRQLRDAMREHIEELRALTISEVG Mb0791|M.bovis_AF2122/97 RAIEAARRAFDSTDWSRNT-ELRVRCVRQLRDAMQQHVEELRELTISEVG Mflv_1797|M.gilvum_PYR-GCK LAVTAARRAFG--TWSQTTREERLELLGAIMAEYQNRAADLADAVHEEMG Mvan_4953|M.vanbaalenii_PYR-1 LAVTAARRAFA--TWSQTTREERLELLGAIMAEYQKRAGDLAEAVTEEMG MSMEG_0455|M.smegmatis_MC2_155 AAVEAARKAFT--TWSQTSRDERLAVLGAILDEYQKRAIDLADAVGEEMG TH_4605|M.thermoresistible__bu NAVRAARRAFP--AWSQSSREERLELLQGILAEYQKRSADLADAVHEEMG MAV_5202|M.avium_104 VAVGAARRAFG--RWSQSSREDRLDLLQAILAEYQKRADDLAAAVTEEIG Rv0223c|M.tuberculosis_H37Rv AAVAAARAAFDNGPWPSTPPHERAAVIAAAVKMLAERKDLFTKLLAAETG MAB_4484|M.abscessus_ATCC_1997 AAVSAARRAFDNGPWPRLTPHERQAVLQKAVSLLESRKDEICKAIADETG MLBr_02573|M.leprae_Br4923 DAIARAYARFDN--YRHTTFTQRAKWANATADLLEAEANQSAALMTLEMG *: * * : . * . * * MMAR_4928|M.marinum_M APRMLTAAAQLEGPVNDLAFSADTAESYSWKQDLGAAAPMGIPTRRTVVR MUL_0477|M.ulcerans_Agy99 APRMLTAAAQLEGPVNDLAFSADTAESYSWKQDLGAAAPMGIPTRRTVVR Mb0791|M.bovis_AF2122/97 APRMLTASAQLEGPVGDLSFAADTAESYPWKQDLGEASPLGIATRRTLAR Mflv_1797|M.gilvum_PYR-GCK APASLASGPQVNLGIGHLATAIDALKNFQFEEQH---------GSTLVVK Mvan_4953|M.vanbaalenii_PYR-1 APAGLASGPQVNLGIGHLATTVDALKNFAFEEQH---------GSTLVVK MSMEG_0455|M.smegmatis_MC2_155 APASLAAGPQVRMGLGHLTTSIEALKKFQFEEQY---------GSTLVVK TH_4605|M.thermoresistible__bu APPSLAKGPQVNMGLGHLTTAIDVLKNFSFEEQR---------GATLVVK MAV_5202|M.avium_104 APPSLAAGPQVFLGIGHLTTAIEVLKNFAFTEQR---------GATLIAR Rv0223c|M.tuberculosis_H37Rv QPPTIIETMHWMGSMGAMNYFAGAADKVTWTETRTGSY-----GQSIVSR MAB_4484|M.abscessus_ATCC_1997 APPMVIETLQWMGGFGAIQYYANAADAVKWKELRNGAY-----GQTLVTR MLBr_02573|M.leprae_Br4923 KTLQSAKDEAMKCAKGFRYYAEKAETLLADEPAEAAAVG---ASKALARY . . . MMAR_4928|M.marinum_M EAVGVVGAITPWNFPHQINLAKLGPALAAGNTVVLKPAPDTPWCAAVLGE MUL_0477|M.ulcerans_Agy99 EAVGVVGAITPWNFPHQINLAKLGPALAAGNTVVLKPAPDTPWCAAVLGE Mb0791|M.bovis_AF2122/97 EAVGVVGAITPWNFPHQINLAKLGPALAAGNTVVLKPAPDTPWCAAALGE Mflv_1797|M.gilvum_PYR-GCK EPIGVCGLITPWNWPINQIACKVFPALATGNTMVLKPSEVAPYSAQIFTE Mvan_4953|M.vanbaalenii_PYR-1 EPIGVCGLITPWNWPINQIACKVFPALATGNTMVLKPSEVAPYSAQIFTE MSMEG_0455|M.smegmatis_MC2_155 EPIGVCGLITPWNWPINQIACKVFPALATGCTMVLKPSEVAPFSAQIFTE TH_4605|M.thermoresistible__bu EPIGVCGLITPWNWPLNQIACKVFPALATGCTMVLKPSEVAPYSGQIFTE MAV_5202|M.avium_104 EPIGVCGLITPWNWPINQVAVKVYPALATGCTVVLKPSEVAPFSSYIFAE Rv0223c|M.tuberculosis_H37Rv EPVGVVGAIVAWNVPLFLAVNKIAPALLAGCTIVLKPAAETPLTANALAE MAB_4484|M.abscessus_ATCC_1997 EPAGVVAAIAAWNVPLFLALNKIGPAFLAGCAVVLKPAAETPLSSFILAE MLBr_02573|M.leprae_Br4923 QPLGVVLAVMPWNFPLWQTVRFAAPALMAGNVGLLKHASNVPQCALYLAD :. ** : .** * **: :* . :** : .* . : : MMAR_4928|M.marinum_M LIADCTDIPPGVVNIVTSSEHGLGALLAKDPRVDMVSFTGSTATGRSVMA MUL_0477|M.ulcerans_Agy99 LIADCTDIPPGVVNIVTSSEHGLGALLAKDPRVDMVSFTGSTATGRSVMA Mb0791|M.bovis_AF2122/97 IIVEHTDFPPGVVNIVTSSSHALGALLAKDPRVDMISFTGSTATGRAVMA Mflv_1797|M.gilvum_PYR-GCK ILDAAG-VPAGVYNLVYGDGPGVGAAISSHPEIDMVSFTGSTRAGIEVAR Mvan_4953|M.vanbaalenii_PYR-1 IIDAAG-VPAGVYNLVYGDGPGVGASISSHPDIDMVSFTGSTRAGIEIAR MSMEG_0455|M.smegmatis_MC2_155 IIEAAG-VPAGVYNLVYGDGPGVGSALSSHPDIDMVSFTGSTRAGIDVAR TH_4605|M.thermoresistible__bu ILDTAG-VPAGVYNMVFGDGPGVGVALSSHPDVDLVSFTGSTRAGVDVAR MAV_5202|M.avium_104 ILAAAG-VPAGVFNLVNGDGPGVGAALASHPDIDLVSFTGSTRAGVEVAR Rv0223c|M.tuberculosis_H37Rv VFAEVG-LPEGVLSVVPG-GIETGQALTSNPDIDMFTFTGSSAVGREVGR MAB_4484|M.abscessus_ATCC_1997 VFAEAG-VPEGVLSVVPG-GAETGRALTNNPDVDVFSFTGSTAVGKEIAE MLBr_02573|M.leprae_Br4923 VIARGG-FPEDCFQTLLISANGVEAILR-DPRVAAATLTGSEPAGQAVGA :: .* . . : : .* : ::*** .* : MMAR_4928|M.marinum_M DGAATIKRMFLELGGKSAFIVLDDADLAAASSVSAFTASMHAGQGCAITT MUL_0477|M.ulcerans_Agy99 DGAATIKRMFLELGGKSAFIVLDDADLAAASSVSAFTASMHAGQGCAITT Mb0791|M.bovis_AF2122/97 DAAATIKKVFLELGGKSAFVVLDDADLAAASAVSAFSACMHAGQGCAITT Mflv_1797|M.gilvum_PYR-GCK NAAPTVKRVTQELGGKSPNIVLDDDDFAKSVAAGTSVMMVNSGQSCNAPS Mvan_4953|M.vanbaalenii_PYR-1 NAAPTVKRVTQELGGKSPNIVLDDDDFAKSVAAGTSVMMVNSGQSCNAPS MSMEG_0455|M.smegmatis_MC2_155 NAAPTVKRVTQELGGKSPNIVLDDADFAKSVAAGVSAMMTNSGQSCNAPS TH_4605|M.thermoresistible__bu NAAPTVKRVTQELGGKSANIVLDDADFAKSVTAGVTTMMLNSGQSCNAPS MAV_5202|M.avium_104 NAAPTVKRVTQELGGKSPNIVLDDGGFADAVRAGVANMMPNSGQSCNAPS Rv0223c|M.tuberculosis_H37Rv RAAEMLKPCTLELGGKSAAIILEDVDLAAAIPMMVFSGVMNAGQGCVNQT MAB_4484|M.abscessus_ATCC_1997 IAAKNLKKVTLELGGKSAAIVLEDADLAAALPMLVFSGLMNAGQGCVNQT MLBr_02573|M.leprae_Br4923 IAGNEIKPTVLELGGSDPFIVMPSADLDAAVATAVTGRVQNNGQSCIAAK .. :* ****... ::: . .: : . : **.* . MMAR_4928|M.marinum_M RLVVPRARYDEAVAIAAGTMSSIKPGDPDDARTVCGPLISQRQRDRVQGY MUL_0477|M.ulcerans_Agy99 RLVVPRARYDEAVAIAAGTMSSIKPGDPDDARTVCGPLISQRQRDRVEGY Mb0791|M.bovis_AF2122/97 RLVVPRARYEEAVAIAAATMSSIRPGDPNDPGTVCGPLISARQRDRVQGY Mflv_1797|M.gilvum_PYR-GCK RMLVPNSRMDEAIAVARETAGAVKVGDPGD-QSAIGPVASRAQFEKIQGL Mvan_4953|M.vanbaalenii_PYR-1 RMLVPNSRMDEAIAVARETAAAVKVGDPSD-KTAIGPVASKAQFDKIQGL MSMEG_0455|M.smegmatis_MC2_155 RMLVPNSRMGEAITIARGTAAAVKVGDPSD-KKAIGPVASKAQFDKIQGL TH_4605|M.thermoresistible__bu RMLVPNSRMDEAIEIARETAAQVAVGDPDN-KTAIGPVVSRVQFDKIQRL MAV_5202|M.avium_104 RMLVPASRMAEAISIAREVAEQVQVGDPDD-ATAIGPVASRAQFEKVQRL Rv0223c|M.tuberculosis_H37Rv RILAPRSRYDEIVAAVTNFVTALPVGPPSDPAAQIGPLISEKQRTRVEGY MAB_4484|M.abscessus_ATCC_1997 RVLAPRSRYDEVVDGIVGMVSLMGVGLPDDPATQVGPLITEKQRTRVEGY MLBr_02573|M.leprae_Br4923 RFIAHADIYDEFVEKFVARMETLRVGDPTDPDTDVGPLATESGRAQVEQQ *.:. * : : * * : **: : ::: MMAR_4928|M.marinum_M LDLAIAEGGTFACGG-GRPAGRQVGYFIEPTVIAGLTNDARPAREEIFGP MUL_0477|M.ulcerans_Agy99 LDLAIAEGGTFACGG-GRPAGRQVGYFIEPTVIAGLTTDARPAREEIFGP Mb0791|M.bovis_AF2122/97 LDLAVAEGGRFACGG-ARPADREVGFYIEPTVIAGLTNDARVAREEIFGP Mflv_1797|M.gilvum_PYR-GCK IQKGIDEGATLVVGGTGRPDGVDKGYYVKPTVFANVTNDMTIAREEIFGP Mvan_4953|M.vanbaalenii_PYR-1 IQKGIDEGATLVIGGTGRPDGIDKGYYVKPTVFANVTNDMTIAREEIFGP MSMEG_0455|M.smegmatis_MC2_155 IQKGIDEGATLVAGGTGRPDGLDTGYYVKPTVFADVTNDMTIAREEIFGP TH_4605|M.thermoresistible__bu IQQGIDEGATVVVGGPGRPDGLEVGYYVKPTVFANVKNDMTIAREEIFGP MAV_5202|M.avium_104 IQQGIDEGATVVAGGPGRPAGLDQGYYVKPTVFADVTNDMTIAREEIFGP Rv0223c|M.tuberculosis_H37Rv IAKGIEEGARLVCGG-GRPEGLDNGFFIQPTVFADVDNKMTIAQEEIFGP MAB_4484|M.abscessus_ATCC_1997 IAKGIAEGARLAYGG-KRPEGLDGGYFVQPTIFADVDNSMTIAQEEIFGP MLBr_02573|M.leprae_Br4923 VDAAAAAGAVIRCGG-KRPD--RPGWFYPPTVITDITKDMALYTDEVFGP : . *. . ** ** *:: **:::.: .. :*:*** MMAR_4928|M.marinum_M VLTVLAHDGDDDAVRIANDSPYGLSGTVYGGDPQRAADVAARLRVGTVNV MUL_0477|M.ulcerans_Agy99 VLTVLAHDGDDDAVRIANDSPYGLSGTVYGGDPQRAADVAARLRVGAVNV Mb0791|M.bovis_AF2122/97 VLTVIAHDGDDDAVRIANDSPYGLSGTVYGADPQRAARIASRLRVGTVNV Mflv_1797|M.gilvum_PYR-GCK VLCILGYDDLDQAVAIGNDTEYGLAGYVSGSDLEQARAVARRIRAGSVAI Mvan_4953|M.vanbaalenii_PYR-1 VLCILGYDDLDQAVEIGNDTEYGLAGYVSGADLDKARAVARRIRAGSVAI MSMEG_0455|M.smegmatis_MC2_155 VLCILGYDDLDQAVEIANDTEYGLAGYVSGADLETARAVARRIRAGSVAI TH_4605|M.thermoresistible__bu VLCILGYDDLDDAIEIANDTDYGLAGYVSGSDLEQARALARRIRAGSIAI MAV_5202|M.avium_104 VLCILGYDDLDHAVRLANDTDYGLAGYVSGADLDTAREVAGKIRAGWVTI Rv0223c|M.tuberculosis_H37Rv VLAIIPYDTEEDAIAIANDSVYGLAGSVWTTDVPKGIKISQQIRTGTYGI MAB_4484|M.abscessus_ATCC_1997 VLSIIAYDSVDEAVKIANDSNYGLAGSVWTTDVQKGLEVAAQIRTGTYGI MLBr_02573|M.leprae_Br4923 VASVYCATNIDDAIEIANATPFGLGSNAWTQNESEQRHFIDNIVAGQVFI * : :.*: :.* : :**.. . : . .: .* : MMAR_4928|M.marinum_M NGGVWYCADAPFGGYKQSGIGREMGLAGFEEYLETKLIA-----TAAN-- MUL_0477|M.ulcerans_Agy99 NGGVWYCADAPFGGYKQSGIGREMGLAGFEEYLETKLIA-----TAAN-- Mb0791|M.bovis_AF2122/97 NGGVWYCADAPFGGYKQSGIGREMGLLGFEEYLEAKLIA-----TAAN-- Mflv_1797|M.gilvum_PYR-GCK N--HGFDMAAPFGGYKRSGNGREWGPFAFDEFLEVKAAL---GYAPA--- Mvan_4953|M.vanbaalenii_PYR-1 N--HGFDMAAPFGGYKRSGNGREWGPFAFDEFLEVKAAL---GYAPA--- MSMEG_0455|M.smegmatis_MC2_155 N--HGFDLSAPFGGYKRSGNGREWGHFGFDEYLETKAAM---GYAPPQ-- TH_4605|M.thermoresistible__bu N--HGFDLNAPFGGYKRSGNGREWSDYGFHEYLETKAIL---GYSPS--- MAV_5202|M.avium_104 N--HAFDLNAPFGGYKRSGNGREWSDFGFHEYLEVKSIL---GYAPAQAD Rv0223c|M.tuberculosis_H37Rv NW-YAFDPGSPFGGYKNSGIGRENGPEGVEHFTQQKSVLLPMGYTVA--- MAB_4484|M.abscessus_ATCC_1997 NW-YAFDPSCPFGGYKQSGIGRENGPEGIEEYCELKSVLLPMGYTLESI- MLBr_02573|M.leprae_Br4923 NGMTVSYPELPFGGIKRSGYGRELSTHGIREFCNIKTVWIA--------- * **** *.** *** . .. .: : * MMAR_4928|M.marinum_M - MUL_0477|M.ulcerans_Agy99 - Mb0791|M.bovis_AF2122/97 - Mflv_1797|M.gilvum_PYR-GCK - Mvan_4953|M.vanbaalenii_PYR-1 - MSMEG_0455|M.smegmatis_MC2_155 - TH_4605|M.thermoresistible__bu - MAV_5202|M.avium_104 R Rv0223c|M.tuberculosis_H37Rv - MAB_4484|M.abscessus_ATCC_1997 - MLBr_02573|M.leprae_Br4923 -