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M. thermoresistible (build 8) TH_4562 (-)

annotation: FadE12_1
coordinates: 3943273 - 3944451
length: 393

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4562--100% (393)FadE12_1
M. thermoresistible (build 8)TH_3553-6e-7137.53% (397) PUTATIVE acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)TH_3057-3e-6837.40% (393) PUTATIVE acyl-CoA dehydrogenase domain protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0997cfadE126e-7136.90% (393) acyl-CoA dehydrogenase FADE12
M. gilvum PYR-GCKMflv_2442-0.085.20% (392) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37RvRv0972cfadE121e-7036.90% (393) acyl-CoA dehydrogenase FADE12
M. leprae Br4923MLBr_00737fadE256e-4931.71% (369) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977MAB_2065c-8e-7239.19% (393) acyl-CoA dehydrogenase FadE
M. marinum MMMAR_4741fadE12_10.081.63% (392) acyl-CoA dehydrogenase FadE12_1
M. avium 104MAV_1088-7e-7036.73% (392) acyl-CoA dehydrogenase fadE12
M. smegmatis MC2 155MSMEG_4836-0.089.14% (396) FadE12_1
M. ulcerans Agy99MUL_4707fadE123e-7037.31% (394) acyl-CoA dehydrogenase FadE12
M. vanbaalenii PYR-1Mvan_4210-0.085.46% (392) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb0997c|M.bovis_AF2122/97           -------MTDTSFIESEERQALRKAVASWVANYGHEYYLDKARKHEHTSE
Rv0972c|M.tuberculosis_H37Rv        -------MTDTSFIESEERQALRKAVASWVANYGHEYYLDKARKHEHTSE
MUL_4707|M.ulcerans_Agy99           ------MMTGTSFIENEDRRALRKAVSEWASNYGHEYYLKKARAHEHTTE
MAV_1088|M.avium_104                -------MTDSSFIENEERQALRKAVAEWASNYGSEYYLRKARAHEHTNE
MAB_2065c|M.abscessus_ATCC_199      ----------MELHETEERQDLRKAVAEIAKDFGHEYYLEKSLAGAKSTE
TH_4562|M.thermoresistible__bu      ----------MHFELTEDQELIRASVRELAAKFDDTYWMEKDLNHEFPQE
MSMEG_4836|M.smegmatis_MC2_155      ----MYVSGGMNFELTEDQQLIRSSVAELAAKFDDHYWMAKDQAHEFPQE
Mflv_2442|M.gilvum_PYR-GCK          ------MPG-MSFELTEDQELIRKSVAELCSKFDDHYWMEKDQNHEFPQE
Mvan_4210|M.vanbaalenii_PYR-1       ---MTSMPGGMSFELTEDQELIRKSVRELASRFDDHYWMEKDQAHEFPQE
MMAR_4741|M.marinum_M               ----------MDFELTEDQELIRRSVAELASRFDDHYWMEKDQAHEFPAE
MLBr_00737|M.leprae_Br4923          MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFPEE
                                                :   *::. :* ::          :          . *

Mb0997c|M.bovis_AF2122/97           LWAEAGKLGFLGVNLPEEYGGGGAGMYELSLVMEEMAAAGSAL-LLMVVS
Rv0972c|M.tuberculosis_H37Rv        LWAEAGKLGFLGVNLPEEYGGGGAGMYELSLVMEEMAAAGSAL-LLMVVS
MUL_4707|M.ulcerans_Agy99           LWSEAGKLGFIGVNLPEEYGGGGAGMYELSMVMEEMAAAGSAL-LLMVVS
MAV_1088|M.avium_104                LWSEAGKLGFLGVNLPEEYGGGGAGMYELSLVMEEMAAAGSAL-LLMVVS
MAB_2065c|M.abscessus_ATCC_199      LWQAVGKQGFLGVNLSEQYGGGGGGIYDMQIVGEELAAAGCPL-LMTVVS
TH_4562|M.thermoresistible__bu      FYDAIAGGGWLGMTIPEEYGGHGLGITEATILAEEVARSGGGMNAASSIH
MSMEG_4836|M.smegmatis_MC2_155      FYDAIAGGGWLGMTIPEQYGGHGLGITEATILAEEVARSGGGMNAASAIH
Mflv_2442|M.gilvum_PYR-GCK          FYDAISKGGWLGMTIPEEYGGHGLGITEATLLLEEVSRSGAAMNGASAIH
Mvan_4210|M.vanbaalenii_PYR-1       FYDAIANGGWLGMTIPEEYGGHGLGITEATLLLEEVSRSGAAMNGASAIH
MMAR_4741|M.marinum_M               FYRAIADGGWLGMTIPTEYGGHGLGITEATILLEEVAKSGGAMNAASSIH
MLBr_00737|M.leprae_Br4923          ALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVN
                                            *: .: :. :*** * .     :: **::  .        : 

Mb0997c|M.bovis_AF2122/97           PAING-TIIAKFGTDDQKKRWLPGIADGSLTMAFAITEPDAGSNSHKITT
Rv0972c|M.tuberculosis_H37Rv        PAING-TIIAKFGTDDQKKRWLPGIADGSLTMAFAITEPDAGSNSHKITT
MUL_4707|M.ulcerans_Agy99           PAING-TIISKFGTDEQKQRWLPGIADGTLTMAFAITEPEAGSNSHKITT
MAV_1088|M.avium_104                PAING-TIISKFGTEEQKKRWLPGIADGTLTMAFAITEPDAGSNSHKITT
MAB_2065c|M.abscessus_ATCC_199      PTICG-TIIQAFGSEELKQQWLPGIASGETIMAFAITEPDAGSNSHNIST
TH_4562|M.thermoresistible__bu      LSIFGMQPVVLFGSDEMKAATLPRIVDGSLHVCFGVTEPGAGLDTTRITT
MSMEG_4836|M.smegmatis_MC2_155      MSIFGMQPVVVFGSDEMKAETLPRIVDGDLHVCFGVTEPGAGLDTSRITT
Mflv_2442|M.gilvum_PYR-GCK          LSIFGMQPVVKHGSDELKAATLPRIVDGDLHVCFGVTEPGAGLDTSRITT
Mvan_4210|M.vanbaalenii_PYR-1       LSIFGMQPVVKHGSDELKAATLPRIVNGDLHVCFGVTEPGAGLDTSRITT
MMAR_4741|M.marinum_M               LSIFGMQPVVVHGSDELKARTLPSVATGETHVCFGVTEPGAGLDTSRITT
MLBr_00737|M.leprae_Br4923          --KLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMRT
                                        *   :   *::: *   ** :.      .:.::*  ** ::  : *

Mb0997c|M.bovis_AF2122/97           TARRDGSD----WIIKGQKVFISGIDQAQAVLVVGRSEEAKTGKLR----
Rv0972c|M.tuberculosis_H37Rv        TARRDGSD----WIIKGQKVFISGIDQAQAVLVVGRSEEAKTGKLR----
MUL_4707|M.ulcerans_Agy99           TARRDGSD----WIIKGQKVYISGIDQAQAVLVVGRTEEAKTGKLR----
MAV_1088|M.avium_104                TARRDGSD----WILKGQKVFISGIDQAQAVLVVARTEEAKTGKLR----
MAB_2065c|M.abscessus_ATCC_199      TAKRDGDD----WVINGTKYYISGVDEAEAILVVTRTSTNDSGRGL----
TH_4562|M.thermoresistible__bu      FARREGDH----YVVNGRKVWISKAMESEKILLLARTEPLDAAERPGTKK
MSMEG_4836|M.smegmatis_MC2_155      FARRDGDHPDADYVVNGRKVWISKALESEKILLLTRTESREDVEKRGGKP
Mflv_2442|M.gilvum_PYR-GCK          FAKREGDH----YRVNGRKVWISKALESEKILLLTRTETPEDLKQRGAKK
Mvan_4210|M.vanbaalenii_PYR-1       FAKREGDK----YRVNGRKVWISKALESEKILLLTRTESPDDLEKRGAKK
MMAR_4741|M.marinum_M               FAKRDGDR----YVVNGRKVWISKAVESDKILLLTRTQSYDEVK----KK
MLBr_00737|M.leprae_Br4923          RAKADGDD----WILNGFKCWITNGGKSTWYTVMAVTDPDKGANG-----
                                     *: :*.     : ::* * :*:   ::    ::  :.  .  .      

Mb0997c|M.bovis_AF2122/97           ---PALFVVPTDAPGFSYTP-IEMELVSPERQFQVFLDDVRLPADALVGA
Rv0972c|M.tuberculosis_H37Rv        ---PALFVVPTDAPGFSYTP-IEMELVSPERQFQVFLDDVRLPADALVGA
MUL_4707|M.ulcerans_Agy99           ---PALFVVPTDTPGFTYTA-IDMELVSPERQFQVFLDDVRLPADALVGA
MAV_1088|M.avium_104                ---PALFVVPTDAPGFSATP-IEMELISPERQFQVFLDDVRLPSDALVGA
MAB_2065c|M.abscessus_ATCC_199      ---LSLLVVPTDVPGLTKSL-IPVQAVTPEKQFTLFFDDVRVPAANLIGT
TH_4562|M.thermoresistible__bu      TDGLSLFLTDLDRDHVDIRP-IKKMGRNAVGSNELFIDDLRVPVEDRIGE
MSMEG_4836|M.smegmatis_MC2_155      TEGLSLFLTDLDRDHVDIRP-INKMGRNAVSSNELFIDDLRVPVEHRIGE
Mflv_2442|M.gilvum_PYR-GCK          TDGMTLFLTDLDRDHVDIRP-IRKMGRNAVSSNELFIDDLMVPVEHRVGE
Mvan_4210|M.vanbaalenii_PYR-1       TDGMTLFLTDLDRNHVDIRP-IRKMGRNAVSSNEVFIDDLMVPVEHRVGE
MMAR_4741|M.marinum_M               TDGMTLFITDLDRSRVEVRP-IRKMGRNAVSSNELFIDNLEIPVEDRIGE
MLBr_00737|M.leprae_Br4923          ---ISAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGE
                                        : ::.  *   .           .      :::*.  :*    :* 

Mb0997c|M.bovis_AF2122/97           EDAAIAHLFAGLNPERIMGAASAVGMGRFALGRAVDYVKTRKVWSTPIGA
Rv0972c|M.tuberculosis_H37Rv        EDAAIAQLFAGLNPERIMGAASAVGMGRFALGRAVDYVKTRKVWSTPIGA
MUL_4707|M.ulcerans_Agy99           QDAAIAQLFAGLNPERIMGAASAVGMGRFALNRAVDYVKTRQVWSTPIGA
MAV_1088|M.avium_104                EDAAIAQLFAGLNPERIMGAASSVGMGRFALARAAEYVKTRQVWGTPVGA
MAB_2065c|M.abscessus_ATCC_199      ENEGLRQVFMGLNPERIMGAALGNGIGRYALDKAADYARNRHVWGAPIGS
TH_4562|M.thermoresistible__bu      EGKGFSYILHGLNPERMLIAAEALGIGRVALDRAVKYANERHVFDRPIGM
MSMEG_4836|M.smegmatis_MC2_155      EGKGFGYILHGLNPERMLIAAEALGIGRVALDRAVKYANDRVVFDRPIGM
Mflv_2442|M.gilvum_PYR-GCK          EGQGFKYILDGLNPERMLIAAEALGIGRVALEKAVKYGNERVVFNRPIGM
Mvan_4210|M.vanbaalenii_PYR-1       EGKGFKYILDGLNPERMLIAAEALGIGRVALEKAVKYGNERHVFNRPIGM
MMAR_4741|M.marinum_M               EGNGFQYILDGLNPERMLIAAEALGIGRVALDKAVKYGNEREVFGRPIGM
MLBr_00737|M.leprae_Br4923          PGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESIST
                                     . .:   :  *:  *   .* . *:.: **  *  * . *  :. .:. 

Mb0997c|M.bovis_AF2122/97           HQGLAHPLAQCHIEVELAKLMTQKAATLYDHGDDFGAAEAANMAKYAAAE
Rv0972c|M.tuberculosis_H37Rv        HQGLAHPLAQCHIEVELAKLMTQKAATLYDHGDDFGAAEAANMAKYAAAE
MUL_4707|M.ulcerans_Agy99           HQGLAHPLAQCHIEVELAKLMMQKAATLYDHGDDGGAAEAANMAKYAAAE
MAV_1088|M.avium_104                HQGLSHPLAQCHIEVELAKLMMQKAATLYDAGNDMGAAEAANMAKYAAAE
MAB_2065c|M.abscessus_ATCC_199      HQGVSHPLAHAKIQVELARLMTQRAAALHDAGDP-GSGEASNMAKYAAAE
TH_4562|M.thermoresistible__bu      NQGIQFPLADSLARLDAAELVLRKATWLYDNGKP--CGREANMAKYLCAD
MSMEG_4836|M.smegmatis_MC2_155      NQGIQFPLADSLARLDAAELVLRKATWLYDNGKP--CGREANMAKYLCAD
Mflv_2442|M.gilvum_PYR-GCK          NQGLQFPLADSLARLDAAELVLRKATWLYDNGKP--CGREANTAKYLCAD
Mvan_4210|M.vanbaalenii_PYR-1       NQGLQFPLADSLARLDAAELVLRKATWLYDNGKP--CGREANTAKYLCAD
MMAR_4741|M.marinum_M               NQGLQFPLADSLARLDAAELMLRKATWLYDNGKP--CGREANTAKYLCAD
MLBr_00737|M.leprae_Br4923          FQSIQFMLADMAMKVEAARLIVYAAAARAERGEP-DLGFISAASKCFASD
                                     *.: . **.   .:: *.*:   *:   : *.    .  :  :*  .::

Mb0997c|M.bovis_AF2122/97           ASSRAVDQAVQSMGGNGLTKEYGVAAMMTSARLARIAPISREMVLNFVAQ
Rv0972c|M.tuberculosis_H37Rv        ASSRAVDQAVQSMGGNGLTKEYGVAAMMTSARLARIAPISREMVLNFVAQ
MUL_4707|M.ulcerans_Agy99           ASARSVDQAVQSMGGNGLTQEYGVAAMLTSSRLARIAPISREMVLNFVAQ
MAV_1088|M.avium_104                AATRSVDQAVQSMGGNGLTKEYGVAAMLASARLGRIAPVSREMVLNFVAQ
MAB_2065c|M.abscessus_ATCC_199      AGILALDQAIQTHGGNGMATEYGLATLWGPARLMRTAPISREMILNFVAQ
TH_4562|M.thermoresistible__bu      AGFAAADRALQTHGGMGYSEEYSISRFFRESRLMKIAPVSQEMILNYLGS
MSMEG_4836|M.smegmatis_MC2_155      AGFAAADRALQTHGGMGYSEEYNISRFFRESRLMKIAPVSQEMILNFLGA
Mflv_2442|M.gilvum_PYR-GCK          AGFGAADRALQLHGGMGYSEEYHVSRYFRESRLMKIAPVSQEMILNFLGE
Mvan_4210|M.vanbaalenii_PYR-1       AGFGAADRALQLHGGMGYSEEYHVSRYFRESRLMKIAPVSQEMILNFLGE
MMAR_4741|M.marinum_M               AGFAAADRALQTHGGMGYAEEYHVARYFREARLMKIAPVSQEMILNFLGS
MLBr_00737|M.leprae_Br4923          IAMEVTTDAVQLFGGAGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSR
                                     .      *:*  ** * : :: :      ::: :    :.::    :. 

Mb0997c|M.bovis_AF2122/97           TSLGLPRSY
Rv0972c|M.tuberculosis_H37Rv        TSLGLPRSY
MUL_4707|M.ulcerans_Agy99           TSLGLPRSY
MAV_1088|M.avium_104                TSLGLPRSY
MAB_2065c|M.abscessus_ATCC_199      HSLKLPASY
TH_4562|M.thermoresistible__bu      HVLGLPRSY
MSMEG_4836|M.smegmatis_MC2_155      NVLGLPKSY
Mflv_2442|M.gilvum_PYR-GCK          HVLGLPRSY
Mvan_4210|M.vanbaalenii_PYR-1       HVLGLPRSY
MMAR_4741|M.marinum_M               HVLKLPRSY
MLBr_00737|M.leprae_Br4923          ALLR-----
                                      *