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ELHETEERQDLRKAVAEIAKDFGHEYYLEKSLAGAKSTELWQAVGKQGFLGVNLSEQYGGGGGGIYDMQI VGEELAAAGCPLLMTVVSPTICGTIIQAFGSEELKQQWLPGIASGETIMAFAITEPDAGSNSHNISTTAK RDGDDWVINGTKYYISGVDEAEAILVVTRTSTNDSGRGLLSLLVVPTDVPGLTKSLIPVQAVTPEKQFTL FFDDVRVPAANLIGTENEGLRQVFMGLNPERIMGAALGNGIGRYALDKAADYARNRHVWGAPIGSHQGVS HPLAHAKIQVELARLMTQRAAALHDAGDPGSGEASNMAKYAAAEAGILALDQAIQTHGGNGMATEYGLAT LWGPARLMRTAPISREMILNFVAQHSLKLPASY*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2065c | - | - | 100% (384) | acyl-CoA dehydrogenase FadE |
| M. abscessus ATCC 19977 | MAB_1070c | - | e-124 | 57.74% (381) | acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_1863 | - | 1e-48 | 32.80% (372) | acyl-CoA dehydrogenase FadE |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0997c | fadE12 | 1e-129 | 59.06% (381) | acyl-CoA dehydrogenase FADE12 |
| M. gilvum PYR-GCK | Mflv_4615 | - | 0.0 | 87.24% (384) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv0972c | fadE12 | 1e-130 | 59.32% (381) | acyl-CoA dehydrogenase FADE12 |
| M. leprae Br4923 | MLBr_00737 | fadE25 | 3e-36 | 29.86% (365) | putative acyl-CoA dehydrogenase |
| M. marinum M | MMAR_4535 | fadE12 | 1e-131 | 59.58% (381) | acyl-CoA dehydrogenase FadE12 |
| M. avium 104 | MAV_1088 | - | 1e-131 | 59.58% (381) | acyl-CoA dehydrogenase fadE12 |
| M. smegmatis MC2 155 | MSMEG_5494 | - | 1e-133 | 60.10% (381) | acyl-CoA dehydrogenase fadE12 |
| M. thermoresistible (build 8) | TH_3553 | - | 1e-130 | 59.38% (384) | PUTATIVE acyl-CoA dehydrogenase domain protein |
| M. ulcerans Agy99 | MUL_4707 | fadE12 | 1e-131 | 59.32% (381) | acyl-CoA dehydrogenase FadE12 |
| M. vanbaalenii PYR-1 | Mvan_4850 | - | 1e-132 | 59.74% (385) | acyl-CoA dehydrogenase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_2065c|M.abscessus_ATCC_199 ----------MELHETEERQDLRKAVAEIAKDFGHEYYLEKSLAGAKSTE
Mflv_4615|M.gilvum_PYR-GCK ----------MELHETEERRALRKAVSEIAKDFGHDYYVAKSLGGEKSSE
Mb0997c|M.bovis_AF2122/97 -------MTDTSFIESEERQALRKAVASWVANYGHEYYLDKARKHEHTSE
Rv0972c|M.tuberculosis_H37Rv -------MTDTSFIESEERQALRKAVASWVANYGHEYYLDKARKHEHTSE
MMAR_4535|M.marinum_M -------MTDTSFIENEDRRALRKAVSEWASNYGHEYYLKKARAHEHTTE
MUL_4707|M.ulcerans_Agy99 ------MMTGTSFIENEDRRALRKAVSEWASNYGHEYYLKKARAHEHTTE
MAV_1088|M.avium_104 -------MTDSSFIENEERQALRKAVAEWASNYGSEYYLRKARAHEHTNE
MSMEG_5494|M.smegmatis_MC2_155 ---------MSGFVETEEQQALRRAVAAMAANYGQDYYLEKARAGQHTTE
TH_3553|M.thermoresistible__bu ---------VTGFVESEEQRALRRAAAELAAGYGQDYYLEKARAGEHTDE
Mvan_4850|M.vanbaalenii_PYR-1 ----------MSFIETDEQQALRKAVAAMAANYGQDYYLEKARAGQHTDE
MLBr_00737|M.leprae_Br4923 MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFPEE
: :::. ** : . : . *
MAB_2065c|M.abscessus_ATCC_199 LWQAVGKQGFLGVNLSEQYGGGGGGIYDMQIVGEELAAAGCPLLMTVVSP
Mflv_4615|M.gilvum_PYR-GCK LWHAVGEQGFLGINIAEEYGGGGGGIYDMQIVGEELAAAGCPLLMTVVSP
Mb0997c|M.bovis_AF2122/97 LWAEAGKLGFLGVNLPEEYGGGGAGMYELSLVMEEMAAAGSALLLMVVSP
Rv0972c|M.tuberculosis_H37Rv LWAEAGKLGFLGVNLPEEYGGGGAGMYELSLVMEEMAAAGSALLLMVVSP
MMAR_4535|M.marinum_M LWSEAGKLGFIGVNLPEEYGGGGAGMYELSMVMEEMAAAGSALLLMVVSP
MUL_4707|M.ulcerans_Agy99 LWSEAGKLGFIGVNLPEEYGGGGAGMYELSMVMEEMAAAGSALLLMVVSP
MAV_1088|M.avium_104 LWSEAGKLGFLGVNLPEEYGGGGAGMYELSLVMEEMAAAGSALLLMVVSP
MSMEG_5494|M.smegmatis_MC2_155 LWNEAGKLGFIGVNLPEEYGGGGAGMYELSLVMEEMAATGCALLMMVVSP
TH_3553|M.thermoresistible__bu LWAEAGKLGFLGVNLPEEYGGGGAGMYELSLVMEELSAAGCGLLMMVVSP
Mvan_4850|M.vanbaalenii_PYR-1 LWSEAGKLGFIGVNLPEEYGGGGAGMYELSLVMEEMAAAGSSLLMMVVSP
MLBr_00737|M.leprae_Br4923 ALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVN
. ** .:::.*:*** *.. :* **:: ... : .
MAB_2065c|M.abscessus_ATCC_199 TICGTIIQAFGSEELKQQWLPGIASGETIMAFAITEPDAGSNSHNISTTA
Mflv_4615|M.gilvum_PYR-GCK TICGTIIQAFGSDELKARWLPGIASGEVIMAFAITEPDAGSNSHNISTYA
Mb0997c|M.bovis_AF2122/97 AINGTIIAKFGTDDQKKRWLPGIADGSLTMAFAITEPDAGSNSHKITTTA
Rv0972c|M.tuberculosis_H37Rv AINGTIIAKFGTDDQKKRWLPGIADGSLTMAFAITEPDAGSNSHKITTTA
MMAR_4535|M.marinum_M AINGTIISKFGTDEQKQRWLPGIADGTLTMAFAITEPDAGSNSHKITTTA
MUL_4707|M.ulcerans_Agy99 AINGTIISKFGTDEQKQRWLPGIADGTLTMAFAITEPEAGSNSHKITTTA
MAV_1088|M.avium_104 AINGTIISKFGTEEQKKRWLPGIADGTLTMAFAITEPDAGSNSHKITTTA
MSMEG_5494|M.smegmatis_MC2_155 AINGTIISKFGTEEQKRRWLPGIADGSITMAFAITEPDAGSNSHRITTTA
TH_3553|M.thermoresistible__bu AINGTIISRFGTEDQKRRWLPGIADGSITMAFAITEPDAGSNSHRITTTA
Mvan_4850|M.vanbaalenii_PYR-1 AINGTIISKFGTEEQKKRWIPGIADGSLTMAFAITEPDAGSNSHKITTTA
MLBr_00737|M.leprae_Br4923 KLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMRTRA
: : *::: * : :*.:* ::*::* :***:: : * *
MAB_2065c|M.abscessus_ATCC_199 KRDGDDWVINGTKYYISGVDEAEAILVVTRTSTNDSG---RGLLSLLVVP
Mflv_4615|M.gilvum_PYR-GCK KRVGGDWILNGTKYYISGVDEAEAILVVTRTATDDRG---RGRLSLLVVP
Mb0997c|M.bovis_AF2122/97 RRDGSDWIIKGQKVFISGIDQAQAVLVVGRSEEAKTG---KLRPALFVVP
Rv0972c|M.tuberculosis_H37Rv RRDGSDWIIKGQKVFISGIDQAQAVLVVGRSEEAKTG---KLRPALFVVP
MMAR_4535|M.marinum_M RRDGSDWIIKGQKVYISGIDQAQAVLVVGRTEEAKTG---KLRPALFVVP
MUL_4707|M.ulcerans_Agy99 RRDGSDWIIKGQKVYISGIDQAQAVLVVGRTEEAKTG---KLRPALFVVP
MAV_1088|M.avium_104 RRDGSDWILKGQKVFISGIDQAQAVLVVARTEEAKTG---KLRPALFVVP
MSMEG_5494|M.smegmatis_MC2_155 RRDGSDWILKGQKVFISGIDQAQAVLVVGRTEDHKTG---NLKPALFVIP
TH_3553|M.thermoresistible__bu RRDGGDWILSGQKVFISGVDQAQAVLVVGRVQKDGTGRTKSLKPALFVVP
Mvan_4850|M.vanbaalenii_PYR-1 RRDGSDWVLSGQKVYISGVDQAQAVLVVGRTEDHKTG---SLKPALFVVP
MLBr_00737|M.leprae_Br4923 KADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDKGAN----GISAFIVH
: *.**::.* * :*:. .:: *: . : :::
MAB_2065c|M.abscessus_ATCC_199 TDVPGLTKSLIPVQA-VTPEKQFTLFFDDVRVPAANLIGTENEGLRQVFM
Mflv_4615|M.gilvum_PYR-GCK TDAPGLTKTLIPVQA-VTPEKQFTLFFDDVRVPAENLIGAENDGLRQVFM
Mb0997c|M.bovis_AF2122/97 TDAPGFSYTPIEMEL-VSPERQFQVFLDDVRLPADALVGAEDAAIAHLFA
Rv0972c|M.tuberculosis_H37Rv TDAPGFSYTPIEMEL-VSPERQFQVFLDDVRLPADALVGAEDAAIAQLFA
MMAR_4535|M.marinum_M TDTPGFTYTAIDMEL-VSPERQFQVFLDDVRLPADALVGAQDAAIAQLFA
MUL_4707|M.ulcerans_Agy99 TDTPGFTYTAIDMEL-VSPERQFQVFLDDVRLPADALVGAQDAAIAQLFA
MAV_1088|M.avium_104 TDAPGFSATPIEMEL-ISPERQFQVFLDDVRLPSDALVGAEDAAIAQLFA
MSMEG_5494|M.smegmatis_MC2_155 TDTPGLHWTKIEMEL-ISPESQFQVFLDDVRVPADALVGSEDAALAQLFA
TH_3553|M.thermoresistible__bu TDAPGLSYTKIEMEL-ISPESQFQVFLDDVRLPADALVGDEDAALAQLFA
Mvan_4850|M.vanbaalenii_PYR-1 TDTPGFTYTKIPMEI-VSPEFQFQVFLDEVRLPADALVGSEDAAIAQLFA
MLBr_00737|M.leprae_Br4923 KDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTGFKTALA
.* *: : :. . :::*. *:*. ::* . .: :
MAB_2065c|M.abscessus_ATCC_199 GLNPERIMGAALGNGIGRYALDKAADYARNRHVWGAPIGSHQGVSHPLAH
Mflv_4615|M.gilvum_PYR-GCK GLNPERIMGAALGNGIGRYALDKASAYARERKVWDVPIGAHQGLSHPLAH
Mb0997c|M.bovis_AF2122/97 GLNPERIMGAASAVGMGRFALGRAVDYVKTRKVWSTPIGAHQGLAHPLAQ
Rv0972c|M.tuberculosis_H37Rv GLNPERIMGAASAVGMGRFALGRAVDYVKTRKVWSTPIGAHQGLAHPLAQ
MMAR_4535|M.marinum_M GLNPERIMGAASAVGMGRFALNRAVDYVKTRQVWSTPIGAHQGLAHPLAQ
MUL_4707|M.ulcerans_Agy99 GLNPERIMGAASAVGMGRFALNRAVDYVKTRQVWSTPIGAHQGLAHPLAQ
MAV_1088|M.avium_104 GLNPERIMGAASSVGMGRFALARAAEYVKTRQVWGTPVGAHQGLSHPLAQ
MSMEG_5494|M.smegmatis_MC2_155 GLNPERIMGAASAVGMGRFAIHKAVDYVKTRQVWKVPIGSHQGLSHPLAQ
TH_3553|M.thermoresistible__bu GLNPERIMGAASAIGMGRFAIGRAVDYVKNRQVWRTPIGAHQGLAHPLAQ
Mvan_4850|M.vanbaalenii_PYR-1 GLNPERIMGAASAVGMGRFAIGRAVEYVKTRQVWKTPIGAHQGLSHPLAQ
MLBr_00737|M.leprae_Br4923 TLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFMLAD
*: * .* . *:.: *: * *.: *: : .:.:.*.: . **.
MAB_2065c|M.abscessus_ATCC_199 AKIQVELARLMTQRAAALHDAGDP-GSGEASNMAKYAAAEAGILALDQAI
Mflv_4615|M.gilvum_PYR-GCK AKIQLELARLMTQRAASLHDADDP-GSAEASNMAKYAAAEAGILALDQAI
Mb0997c|M.bovis_AF2122/97 CHIEVELAKLMTQKAATLYDHGDDFGAAEAANMAKYAAAEASSRAVDQAV
Rv0972c|M.tuberculosis_H37Rv CHIEVELAKLMTQKAATLYDHGDDFGAAEAANMAKYAAAEASSRAVDQAV
MMAR_4535|M.marinum_M CHIEVELAKLMMQKAATLYDHGDDGGAAEAANMAKYAAAEASARSVDQAV
MUL_4707|M.ulcerans_Agy99 CHIEVELAKLMMQKAATLYDHGDDGGAAEAANMAKYAAAEASARSVDQAV
MAV_1088|M.avium_104 CHIEVELAKLMMQKAATLYDAGNDMGAAEAANMAKYAAAEAATRSVDQAV
MSMEG_5494|M.smegmatis_MC2_155 NHIEIELAKLMMQKAAALYDAGDDLGAAEAANMAKYAAGEASVRAVDQAV
TH_3553|M.thermoresistible__bu NHIEIELAKLMMQKAAALYDLGDGAGAAEAANMAKYAAGEASARAVDQAV
Mvan_4850|M.vanbaalenii_PYR-1 NHIEVELAKLMMQKAASLYDAGDDAGAAEAANMAKYAAGEASVRAVDQAV
MLBr_00737|M.leprae_Br4923 MAMKVEAARLIVYAAAARAERGEP-DLGFISAASKCFASDIAMEVTTDAV
:::* *:*: **: : .: . . : :* *.: . :*:
MAB_2065c|M.abscessus_ATCC_199 QTHGGNGMATEYGLATLWGPARLMRTAPISREMILNFVAQHSLKLPASY
Mflv_4615|M.gilvum_PYR-GCK QTHGGNGLATEYGLATLWGPARLMRTAPISREMILNYVAQHSLNLPRSY
Mb0997c|M.bovis_AF2122/97 QSMGGNGLTKEYGVAAMMTSARLARIAPISREMVLNFVAQTSLGLPRSY
Rv0972c|M.tuberculosis_H37Rv QSMGGNGLTKEYGVAAMMTSARLARIAPISREMVLNFVAQTSLGLPRSY
MMAR_4535|M.marinum_M QSMGGNGLTQEYGVAAMLTSSRLARIAPISREMVLNFVAQTSLGLPRSY
MUL_4707|M.ulcerans_Agy99 QSMGGNGLTQEYGVAAMLTSSRLARIAPISREMVLNFVAQTSLGLPRSY
MAV_1088|M.avium_104 QSMGGNGLTKEYGVAAMLASARLGRIAPVSREMVLNFVAQTSLGLPRSY
MSMEG_5494|M.smegmatis_MC2_155 QSLGGNGLTKEYGIAAAVTASKLARIAPVSREMILNFVSQTSLGLPRSY
TH_3553|M.thermoresistible__bu QSLGGNGLTKEYGIAAAITSSRLARIAPISREMILNFVAQTSLGLPRSY
Mvan_4850|M.vanbaalenii_PYR-1 QSLGGNGLTQEYGIASALTASRLARIAPVSREMILNFVAQTSLGLPRSY
MLBr_00737|M.leprae_Br4923 QLFGGAGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR-----
* ** * : :: : ::: : :.:: ::: *