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M. thermoresistible (build 8) TH_3057 (-)

annotation: acyl-CoA dehydrogenase domain protein
coordinates: 38071 - 39231
length: 387

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3057--100% (387)acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)TH_3553-e-12055.47% (384) PUTATIVE acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)TH_4562-3e-6837.40% (393) PUTATIVE FadE12_1

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0997cfadE121e-12155.76% (382) acyl-CoA dehydrogenase FADE12
M. gilvum PYR-GCKMflv_4615-1e-12759.27% (383) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37RvRv0972cfadE121e-12156.02% (382) acyl-CoA dehydrogenase FADE12
M. leprae Br4923MLBr_00737fadE255e-3226.50% (366) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977MAB_2065c-1e-12860.52% (385) acyl-CoA dehydrogenase FadE
M. marinum MMMAR_4535fadE121e-11954.71% (382) acyl-CoA dehydrogenase FadE12
M. avium 104MAV_1088-1e-11954.71% (382) acyl-CoA dehydrogenase fadE12
M. smegmatis MC2 155MSMEG_5494-1e-11753.61% (388) acyl-CoA dehydrogenase fadE12
M. ulcerans Agy99MUL_4707fadE121e-11954.45% (382) acyl-CoA dehydrogenase FadE12
M. vanbaalenii PYR-1Mvan_4850-1e-12557.85% (382) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4615|M.gilvum_PYR-GCK          ----------MELHETEERRALRKAVSEIAKDFGHDYYVAKSLGGEKSSE
MAB_2065c|M.abscessus_ATCC_199      ----------MELHETEERQDLRKAVAEIAKDFGHEYYLEKSLAGAKSTE
TH_3057|M.thermoresistible__bu      --------MSGLLHETDEHRAIRETVAGIAQRYGVHYYLERGRAGGNIDE
Mb0997c|M.bovis_AF2122/97           -------MTDTSFIESEERQALRKAVASWVANYGHEYYLDKARKHEHTSE
Rv0972c|M.tuberculosis_H37Rv        -------MTDTSFIESEERQALRKAVASWVANYGHEYYLDKARKHEHTSE
MMAR_4535|M.marinum_M               -------MTDTSFIENEDRRALRKAVSEWASNYGHEYYLKKARAHEHTTE
MUL_4707|M.ulcerans_Agy99           ------MMTGTSFIENEDRRALRKAVSEWASNYGHEYYLKKARAHEHTTE
MAV_1088|M.avium_104                -------MTDSSFIENEERQALRKAVAEWASNYGSEYYLRKARAHEHTNE
MSMEG_5494|M.smegmatis_MC2_155      ---------MSGFVETEEQQALRRAVAAMAANYGQDYYLEKARAGQHTTE
Mvan_4850|M.vanbaalenii_PYR-1       ---------MS-FIETDEQQALRKAVAAMAANYGQDYYLEKARAGQHTDE
MLBr_00737|M.leprae_Br4923          MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFPEE
                                                :   :::. :* ::   .      :            *

Mflv_4615|M.gilvum_PYR-GCK          LWHAVGEQGFLGINIAEEYGGGGGGIYDMQIVGEELAAAGCPLLMTVVSP
MAB_2065c|M.abscessus_ATCC_199      LWQAVGKQGFLGVNLSEQYGGGGGGIYDMQIVGEELAAAGCPLLMTVVSP
TH_3057|M.thermoresistible__bu      LWKDLGAAGLLGVHLPEEYGGGGGGMAEAVIVVEELAAHGMPLLIWVISP
Mb0997c|M.bovis_AF2122/97           LWAEAGKLGFLGVNLPEEYGGGGAGMYELSLVMEEMAAAGSALLLMVVSP
Rv0972c|M.tuberculosis_H37Rv        LWAEAGKLGFLGVNLPEEYGGGGAGMYELSLVMEEMAAAGSALLLMVVSP
MMAR_4535|M.marinum_M               LWSEAGKLGFIGVNLPEEYGGGGAGMYELSMVMEEMAAAGSALLLMVVSP
MUL_4707|M.ulcerans_Agy99           LWSEAGKLGFIGVNLPEEYGGGGAGMYELSMVMEEMAAAGSALLLMVVSP
MAV_1088|M.avium_104                LWSEAGKLGFLGVNLPEEYGGGGAGMYELSLVMEEMAAAGSALLLMVVSP
MSMEG_5494|M.smegmatis_MC2_155      LWNEAGKLGFIGVNLPEEYGGGGAGMYELSLVMEEMAATGCALLMMVVSP
Mvan_4850|M.vanbaalenii_PYR-1       LWSEAGKLGFIGVNLPEEYGGGGAGMYELSLVMEEMAAAGSSLLMMVVSP
MLBr_00737|M.leprae_Br4923          ALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVN
                                         .  *: .:::.*:*** *..     :* **:*  . .  :     

Mflv_4615|M.gilvum_PYR-GCK          TICGTIIQAFGSDELKARWLPGIASGEVIMAFAITEPDAGSNSHNISTYA
MAB_2065c|M.abscessus_ATCC_199      TICGTIIQAFGSEELKQQWLPGIASGETIMAFAITEPDAGSNSHNISTTA
TH_3057|M.thermoresistible__bu      AICGSILAHHGSDAMRKDWLPTIADGSRRMAFGLTEPDAGSNSHNVKTTA
Mb0997c|M.bovis_AF2122/97           AINGTIIAKFGTDDQKKRWLPGIADGSLTMAFAITEPDAGSNSHKITTTA
Rv0972c|M.tuberculosis_H37Rv        AINGTIIAKFGTDDQKKRWLPGIADGSLTMAFAITEPDAGSNSHKITTTA
MMAR_4535|M.marinum_M               AINGTIISKFGTDEQKQRWLPGIADGTLTMAFAITEPDAGSNSHKITTTA
MUL_4707|M.ulcerans_Agy99           AINGTIISKFGTDEQKQRWLPGIADGTLTMAFAITEPEAGSNSHKITTTA
MAV_1088|M.avium_104                AINGTIISKFGTEEQKKRWLPGIADGTLTMAFAITEPDAGSNSHKITTTA
MSMEG_5494|M.smegmatis_MC2_155      AINGTIISKFGTEEQKRRWLPGIADGSITMAFAITEPDAGSNSHRITTTA
Mvan_4850|M.vanbaalenii_PYR-1       AINGTIISKFGTEEQKKRWIPGIADGSLTMAFAITEPDAGSNSHKITTTA
MLBr_00737|M.leprae_Br4923          KLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMRTRA
                                     :    :   *::  :   :* :*      ::.::* :***::  : * *

Mflv_4615|M.gilvum_PYR-GCK          KRVGGDWILNGTKYYISGVDEAEAILVVTRTATDDR-GRGRLSLLVVPTD
MAB_2065c|M.abscessus_ATCC_199      KRDGDDWVINGTKYYISGVDEAEAILVVTRTSTNDS-GRGLLSLLVVPTD
TH_3057|M.thermoresistible__bu      RRTDSGWVISGSKYYISAVDESDAILLVTRDADLSTPEKSRLSLFVVPTD
Mb0997c|M.bovis_AF2122/97           RRDGSDWIIKGQKVFISGIDQAQAVLVVGRSEEAKT-GKLRPALFVVPTD
Rv0972c|M.tuberculosis_H37Rv        RRDGSDWIIKGQKVFISGIDQAQAVLVVGRSEEAKT-GKLRPALFVVPTD
MMAR_4535|M.marinum_M               RRDGSDWIIKGQKVYISGIDQAQAVLVVGRTEEAKT-GKLRPALFVVPTD
MUL_4707|M.ulcerans_Agy99           RRDGSDWIIKGQKVYISGIDQAQAVLVVGRTEEAKT-GKLRPALFVVPTD
MAV_1088|M.avium_104                RRDGSDWILKGQKVFISGIDQAQAVLVVARTEEAKT-GKLRPALFVVPTD
MSMEG_5494|M.smegmatis_MC2_155      RRDGSDWILKGQKVFISGIDQAQAVLVVGRTEDHKT-GNLKPALFVIPTD
Mvan_4850|M.vanbaalenii_PYR-1       RRDGSDWVLSGQKVYISGVDQAQAVLVVGRTEDHKT-GSLKPALFVVPTD
MLBr_00737|M.leprae_Br4923          KADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDKG--ANGISAFIVHKD
                                    :  ...*::.* * :*:  .::    ::      .       : ::: .*

Mflv_4615|M.gilvum_PYR-GCK          APGLTKTLIPVQA-VTPEKQFTLFFDDVRVPAENLIGAENDGLRQVFMGL
MAB_2065c|M.abscessus_ATCC_199      VPGLTKSLIPVQA-VTPEKQFTLFFDDVRVPAANLIGTENEGLRQVFMGL
TH_3057|M.thermoresistible__bu      APGLTYQQIPTSI-VSPDKQFTVFLDNVEVGEEALIGEAGNGLRQVFDGL
Mb0997c|M.bovis_AF2122/97           APGFSYTPIEMEL-VSPERQFQVFLDDVRLPADALVGAEDAAIAHLFAGL
Rv0972c|M.tuberculosis_H37Rv        APGFSYTPIEMEL-VSPERQFQVFLDDVRLPADALVGAEDAAIAQLFAGL
MMAR_4535|M.marinum_M               TPGFTYTAIDMEL-VSPERQFQVFLDDVRLPADALVGAQDAAIAQLFAGL
MUL_4707|M.ulcerans_Agy99           TPGFTYTAIDMEL-VSPERQFQVFLDDVRLPADALVGAQDAAIAQLFAGL
MAV_1088|M.avium_104                APGFSATPIEMEL-ISPERQFQVFLDDVRLPSDALVGAEDAAIAQLFAGL
MSMEG_5494|M.smegmatis_MC2_155      TPGLHWTKIEMEL-ISPESQFQVFLDDVRVPADALVGSEDAALAQLFAGL
Mvan_4850|M.vanbaalenii_PYR-1       TPGFTYTKIPMEI-VSPEFQFQVFLDEVRLPADALVGSEDAAIAQLFAGL
MLBr_00737|M.leprae_Br4923          DEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTGFKTALATL
                                      *:       .  :. .    :::*. .:    ::*  . .:   :  *

Mflv_4615|M.gilvum_PYR-GCK          NPERIMGAALGNGIGRYALDKASAYARERKVWDVPIGAHQGLSHPLAHAK
MAB_2065c|M.abscessus_ATCC_199      NPERIMGAALGNGIGRYALDKAADYARNRHVWGAPIGSHQGVSHPLAHAK
TH_3057|M.thermoresistible__bu      NPERIMVGALCGGIGRYAIGKAAEYAKERTVWSTPIGAHQGVAHPLAECH
Mb0997c|M.bovis_AF2122/97           NPERIMGAASAVGMGRFALGRAVDYVKTRKVWSTPIGAHQGLAHPLAQCH
Rv0972c|M.tuberculosis_H37Rv        NPERIMGAASAVGMGRFALGRAVDYVKTRKVWSTPIGAHQGLAHPLAQCH
MMAR_4535|M.marinum_M               NPERIMGAASAVGMGRFALNRAVDYVKTRQVWSTPIGAHQGLAHPLAQCH
MUL_4707|M.ulcerans_Agy99           NPERIMGAASAVGMGRFALNRAVDYVKTRQVWSTPIGAHQGLAHPLAQCH
MAV_1088|M.avium_104                NPERIMGAASSVGMGRFALARAAEYVKTRQVWGTPVGAHQGLSHPLAQCH
MSMEG_5494|M.smegmatis_MC2_155      NPERIMGAASAVGMGRFAIHKAVDYVKTRQVWKVPIGSHQGLSHPLAQNH
Mvan_4850|M.vanbaalenii_PYR-1       NPERIMGAASAVGMGRFAIGRAVEYVKTRQVWKTPIGAHQGLSHPLAQNH
MLBr_00737|M.leprae_Br4923          DHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFMLADMA
                                    :  *   .*   *:.: *:  *  *.: *  :  .:.:.*.: . **.  

Mflv_4615|M.gilvum_PYR-GCK          IQLELARLMTQRAASLHDADDPG-SAEASNMAKYAAAEAGILALDQAIQT
MAB_2065c|M.abscessus_ATCC_199      IQVELARLMTQRAAALHDAGDPG-SGEASNMAKYAAAEAGILALDQAIQT
TH_3057|M.thermoresistible__bu      IAVELSRLVTARSAELFDAGEP--AGEAANIAKFAASEAALKALDQAIQT
Mb0997c|M.bovis_AF2122/97           IEVELAKLMTQKAATLYDHGDDFGAAEAANMAKYAAAEASSRAVDQAVQS
Rv0972c|M.tuberculosis_H37Rv        IEVELAKLMTQKAATLYDHGDDFGAAEAANMAKYAAAEASSRAVDQAVQS
MMAR_4535|M.marinum_M               IEVELAKLMMQKAATLYDHGDDGGAAEAANMAKYAAAEASARSVDQAVQS
MUL_4707|M.ulcerans_Agy99           IEVELAKLMMQKAATLYDHGDDGGAAEAANMAKYAAAEASARSVDQAVQS
MAV_1088|M.avium_104                IEVELAKLMMQKAATLYDAGNDMGAAEAANMAKYAAAEAATRSVDQAVQS
MSMEG_5494|M.smegmatis_MC2_155      IEIELAKLMMQKAAALYDAGDDLGAAEAANMAKYAAGEASVRAVDQAVQS
Mvan_4850|M.vanbaalenii_PYR-1       IEVELAKLMMQKAASLYDAGDDAGAAEAANMAKYAAGEASVRAVDQAVQS
MLBr_00737|M.leprae_Br4923          MKVEAARLIVYAAAARAERGEPD-LGFISAASKCFASDIAMEVTTDAVQL
                                    : :* ::*:   :*   : .:    .  :  :*  *.: .     :*:* 

Mflv_4615|M.gilvum_PYR-GCK          HGGNGLATEYGLATLWGPARLMRTAPISREMILNYVAQHSLNLPRSY
MAB_2065c|M.abscessus_ATCC_199      HGGNGMATEYGLATLWGPARLMRTAPISREMILNFVAQHSLKLPASY
TH_3057|M.thermoresistible__bu      HGGNGLSYEYGLSELWFVTRLMRTAPVSREMVLNFVAQTSLGLPRSY
Mb0997c|M.bovis_AF2122/97           MGGNGLTKEYGVAAMMTSARLARIAPISREMVLNFVAQTSLGLPRSY
Rv0972c|M.tuberculosis_H37Rv        MGGNGLTKEYGVAAMMTSARLARIAPISREMVLNFVAQTSLGLPRSY
MMAR_4535|M.marinum_M               MGGNGLTQEYGVAAMLTSSRLARIAPISREMVLNFVAQTSLGLPRSY
MUL_4707|M.ulcerans_Agy99           MGGNGLTQEYGVAAMLTSSRLARIAPISREMVLNFVAQTSLGLPRSY
MAV_1088|M.avium_104                MGGNGLTKEYGVAAMLASARLGRIAPVSREMVLNFVAQTSLGLPRSY
MSMEG_5494|M.smegmatis_MC2_155      LGGNGLTKEYGIAAAVTASKLARIAPVSREMILNFVSQTSLGLPRSY
Mvan_4850|M.vanbaalenii_PYR-1       LGGNGLTQEYGIASALTASRLARIAPVSREMILNFVAQTSLGLPRSY
MLBr_00737|M.leprae_Br4923          FGGAGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR-----
                                     ** * : :: :      ::: :    :.::    :::  *