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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4556 | - | - | 100% (401) | putative cytochrome P450 |
| M. thermoresistible (build 8) | TH_4132 | - | e-165 | 67.41% (402) | PUTATIVE putative cytochrome P450 |
| M. thermoresistible (build 8) | TH_1263 | - | 1e-67 | 35.71% (392) | PROBABLE CYTOCHROME P450 125 CYP125 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0801 | cyp126 | 1e-66 | 39.53% (387) | cytochrome P450 126 |
| M. gilvum PYR-GCK | Mflv_0425 | - | 4e-78 | 40.15% (396) | cytochrome P450 |
| M. tuberculosis H37Rv | Rv0778 | cyp126 | 1e-66 | 39.53% (387) | cytochrome P450 126 |
| M. leprae Br4923 | MLBr_02088 | - | 1e-47 | 32.24% (335) | putative cytochrome p450 |
| M. abscessus ATCC 19977 | MAB_1211c | - | 3e-61 | 32.51% (406) | cytochrome P450 |
| M. marinum M | MMAR_3761 | cyp268A2 | 3e-69 | 39.80% (397) | cytochrome P450 268A2 Cyp268A2 |
| M. avium 104 | MAV_2174 | - | 1e-69 | 37.07% (410) | P450 heme-thiolate protein |
| M. smegmatis MC2 155 | MSMEG_4619 | - | 3e-70 | 39.70% (398) | putative cytochrome P450 126 |
| M. ulcerans Agy99 | MUL_1282 | cyp124A1 | 7e-66 | 36.72% (403) | cytochrome P450 124A1, Cyp124A1 |
| M. vanbaalenii PYR-1 | Mvan_0246 | - | 2e-79 | 40.60% (399) | cytochrome P450 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3761|M.marinum_M --------------MTAISASVRPYDTIDLSSRAFWASSASQRESSFSEL
MSMEG_4619|M.smegmatis_MC2_155 --------------MTVLPIT-RPYDAVDLSSRAFWATTAADREVAFAQL
MAV_2174|M.avium_104 MSLKTRPKKGLATRINGAPPPRVPLADIHLESLDFWGYDDDFRDGAFATL
MUL_1282|M.ulcerans_Agy99 MDLSTNLNTGLLPRVNGTPPPEVPLADIELGSLEFWGRDDDFRDGAFATL
Mb0801|M.bovis_AF2122/97 ---------------MTTAAGLS---GIDLTDLDNFADG--FPHHLFAIH
Rv0778|M.tuberculosis_H37Rv ---------------MTTAAGLS---GIDLTDLDNFADG--FPHHLFAIH
Mflv_0425|M.gilvum_PYR-GCK --------------MPADAITLG---GADLADPDTYLAG--MPYDAFRTL
Mvan_0246|M.vanbaalenii_PYR-1 --------------MATDAISIG---GVDLADPDTYVGG--MPHGAFREL
MAB_1211c|M.abscessus_ATCC_199 ------------MTAMKTAAELGLPEGFDFTDPELYGNR--MPHEEFATL
TH_4556|M.thermoresistible__bu ---------------------------MDMLDLRWRADG--PPHGLFKRM
MLBr_02088|M.leprae_Br4923 -----MRTCVPTRTCVYAFIEYLSHNRPMGTNPPSLVEAQMLLLRLIDPG
. :
MMAR_3761|M.marinum_M RAERPVSWHPPVEDALIQDPNDPGFWAVTRRADIVAVSRTNEVFLSGNGV
MSMEG_4619|M.smegmatis_MC2_155 RAERPVSWHPPVEDALMHDPDDKGFWAVTRHADIVAISRDSETFLSGQGV
MAV_2174|M.avium_104 RREAPISFWPAIEMDGFVAG--NGYWALTKHEDVHFASRHPEIFSSVPNI
MUL_1282|M.ulcerans_Agy99 RREAPISFWPPIELAGLTAG--KGHWALTKHDDIHFASRHPEIFHSSPNI
Mb0801|M.bovis_AF2122/97 RREAPVYWHRPTEHT--P--DGEGFWSVATYAETLEVLRDPVTYSSVTGG
Rv0778|M.tuberculosis_H37Rv RREAPVYWHRPTEHT--P--DGEGFWSVATYAETLEVLRDPVTYSSVTGG
Mflv_0425|M.gilvum_PYR-GCK RREAPVAWHPQV--------DKPGFWALTGYDEIYAVSRDSETWSSQATG
Mvan_0246|M.vanbaalenii_PYR-1 RRHAPVAWHPYG--------DNPGFWALTGYDEVLAVSRDSRTWSSQTTG
MAB_1211c|M.abscessus_ATCC_199 RREAPVWWNPQPRTV--GGFADEGYWVISKHRDVREVSLHTDTFSSGRKG
TH_4556|M.thermoresistible__bu RTEAPVYWYERP--------DGIGYWSVFRHADIHRISHDTETFSSARGG
MLBr_02088|M.leprae_Br4923 TRADPFPVYRALIDYGPMQLPGMPLTVFSSFSDCDEALRHPLSASDRLKA
*. . : .
MMAR_3761|M.marinum_M LF----ENVPAELLEASQSFLA-MDPPRHTKLRKLVSAAFTPRQVRRIED
MSMEG_4619|M.smegmatis_MC2_155 LF----ENVPQELLEASQSFLA-MDAPRHTLIRKLVHSAFTPRQVARIED
MAV_2174|M.avium_104 TI----NDQTPELAEYFGSMIV-LDDPRHQRLRSIVSRAFTPKVVARIEA
MUL_1282|M.ulcerans_Agy99 VI----HDQTPELAEYFGSMIV-LDDPRHQRLRSIVSRAFTPKVVARIEA
Mb0801|M.bovis_AF2122/97 QR-RFGGTVLQD-LPVAGQVLNMMDDPRHTRIRRLVSSGLTPRMIRRVED
Rv0778|M.tuberculosis_H37Rv QR-RFGGTVLQD-LPVAGQVLNMMDDPRHTRIRRLVSSGLTPRMIRRVED
Mflv_0425|M.gilvum_PYR-GCK VF--LDVPAPEDSYQLALMMLT-MDPPRHTALRALVSRGFTPRHVARLGA
Mvan_0246|M.vanbaalenii_PYR-1 VF--LDVPAPEDSYQLSLMMLT-MDPPRHTALRALVSRGFTPRHLARLNA
MAB_1211c|M.abscessus_ATCC_199 AIPRLEDHISPEEFQATLSVLINKDAPEHTQLRGLVSRMFTPRSIAALRI
TH_4556|M.thermoresistible__bu VY---LHPDQQVPLELMRSMMLVMDPPQHTRYRRIVSKVFTPLAVAKMED
MLBr_02088|M.leprae_Br4923 TLAQQAIAAGAEPRPFYASSFMFLDPPDHTRLRKLVSKAFAPKVVQALEG
: * * * * :* ::* : :
MMAR_3761|M.marinum_M SIKINAKGIVDELRMAG--GGVDFVEHCAKELPIRTLSDMVGIPEADRER
MSMEG_4619|M.smegmatis_MC2_155 SIKANAAAIVAELKAAG--SGVDFVDHCAKELPIRTLSDMVGIPEGEREK
MAV_2174|M.avium_104 SVRERARRLVSSLVANHPNGEAELVSELAGPLPLQVICDMMGIPEEDHQR
MUL_1282|M.ulcerans_Agy99 SVRERAHRLVAAMIENHPDGQADLVSELAGPLPLQIICDMMGIPEEDHEQ
Mb0801|M.bovis_AF2122/97 DLRRRARGLLDGVEPGA---PFDFVVEIAAELPMQMICILLGVPETDRHW
Rv0778|M.tuberculosis_H37Rv DLRRRARGLLDGVEPGA---PFDFVVEIAAELPMQMICILLGVPETDRHW
Mflv_0425|M.gilvum_PYR-GCK RTADMARAIVDDALAHG---QCEFVDEVAGALPSYVIAELLGIPLEDGRR
Mvan_0246|M.vanbaalenii_PYR-1 RTADMARDILDAALQRG---ECEFVDDVAGALPSYVIAELLGIPLDDGRR
MAB_1211c|M.abscessus_ATCC_199 TLEERAERIVRAALEGG---HGEFVREVASELPMQAIAELIGVPEEDRVK
TH_4556|M.thermoresistible__bu DIRARVNRTIDNFIEKG---SCDFVEDFAVPVPLGVLLEMMGVPQQDAGV
MLBr_02088|M.leprae_Br4923 DIAALVDSLLDKGAAAG---QFDVIADLAFPLAVAVICRLLGVPYEDAPE
. : :.: . * :. : ::*:* :
MMAR_3761|M.marinum_M VAHAADALVSWADPRYLNGRE---PLAVLFENQMYLHQVAASLAAERRDR
MSMEG_4619|M.smegmatis_MC2_155 VAHAADALVSWADPIYLAGRH---PLEVLLENQMYLHQVANTLAAERREN
MAV_2174|M.avium_104 VFHWTNVILGFGDPDLATD------FEEFLQVSMDIGAYATALAEDRRVN
MUL_1282|M.ulcerans_Agy99 IFHWTNVILGFGDPDLTTD------FDDFLQVSMAIGGYATALADDRRVN
Mb0801|M.bovis_AF2122/97 LFEAVEPGFDFRGSRRATM-----PRLNVEDAGSRLYTYALELIAGKRAE
Rv0778|M.tuberculosis_H37Rv LFEAVEPGFDFRGSRRATM-----PRLNVEDAGSRLYTYALELIAGKRAE
Mflv_0425|M.gilvum_PYR-GCK LYTLTD----IMNTRPLHD-----PELVA--AQMQMFEYAAELAARKRSE
Mvan_0246|M.vanbaalenii_PYR-1 LYALTE----IMNTRPLHD-----PELMQ--TQVELFGYAGDLAASKRAA
MAB_1211c|M.abscessus_ATCC_199 LFEWSN----QMTGYDEAD-----VEIDPRVGAAQILGYSYQLAEQRRDC
TH_4556|M.thermoresistible__bu FSDWTER---LEQAQRVPG-----PLGAVDVFEEMSGYLAAQIEQQTKAA
MLBr_02088|M.leprae_Br4923 FGRVSALLVQSVDPFITITGEPPEATEERLRAGVWLRDYLEQLVKCRRGT
. : :
MMAR_3761|M.marinum_M PGDDLFSALVNAEVD---GDRLADADVAAFFVLLAVAGNDTTRQTISHGL
MSMEG_4619|M.smegmatis_MC2_155 PGNDLISALVHAEVD---GDRLTDAEVAAFFVLLAVAGNDTTRQTTSHAL
MAV_2174|M.avium_104 HHDDLTTSLVEAEVD---GERLTSSEIASFFILLVVAGNETTRNAISHGV
MUL_1282|M.ulcerans_Agy99 HHGDLTTSLVEAEVD---GERLSSSEIAMFFILLVVAGNETTRNTISHGM
Mb0801|M.bovis_AF2122/97 PADDMLSVVANATIDDPDAPALSDAELYLFFHLLFSAGAETTRNSIAGGL
Rv0778|M.tuberculosis_H37Rv PADDMLSVVANATIDDPDAPALSDAELYLFFHLLFSAGAETTRNSIAGGL
Mflv_0425|M.gilvum_PYR-GCK PGDDIATALLHAEVD---GRRLTDLEFNLFFLLLINAGGDTTRNLVAAGT
Mvan_0246|M.vanbaalenii_PYR-1 PGDDIATALLHAEVD---GQRLTDLEFNLFFMLLLNAGGDTTRNLVAAGT
MAB_1211c|M.abscessus_ATCC_199 PGNDVVSRLLTGTVD---GEQLTPEQFGFFVVMLSVAGNETTRNATTMGM
TH_4556|M.thermoresistible__bu VEDSLVMRLRNAEVD---GEKLNDMEIVAVFGLLAFAGNDTTRNTISTGL
MLBr_02088|M.leprae_Br4923 PGEDLISRLIELDES---GDQLTEEEIIATCGLLLVAGHETTVNLIANAV
.: : . . * :. :* ** :** : : .
MMAR_3761|M.marinum_M KALTDFPSQKAWLLADFDTRIGTAVEELVRWATPVMTFRRTAAADFELGG
MSMEG_4619|M.smegmatis_MC2_155 KALTDFEDQRAWLMEDFDDRIGVAVEEMVRWASPVMTFRRTAAVDVELGG
MAV_2174|M.avium_104 LALSRYPDERDKWFSDFDRLTPTAVEEVVRWASPVVYMRRTLTRDVKLRG
MUL_1282|M.ulcerans_Agy99 LALSRYPDERAKWWSDFDGLAATAVEEIVRWASPVVYMRRTLNQDVDLRG
Mb0801|M.bovis_AF2122/97 LALAENPDQLQTLRSDFE-LLPTAIEEIVRWTSPSPSKRRTASRAVSLGG
Rv0778|M.tuberculosis_H37Rv LALAENPDQLQTLRSDFE-LLPTAIEEIVRWTSPSPSKRRTASRAVSLGG
Mflv_0425|M.gilvum_PYR-GCK LALIEHPDQWRRLAADPS-LMPTAVEEMLRWTSPVTVFSRTATRDTDVGG
Mvan_0246|M.vanbaalenii_PYR-1 LALIEHPEQWARLAADPS-LMPTAIEEMLRWTSPVNVFTRTATRDTEVGG
MAB_1211c|M.abscessus_ATCC_199 MAFLEHPGQWELFKSAR---PSTTVDEIVRYTSPLISQQRTALQDTVISD
TH_4556|M.thermoresistible__bu RALIDHPQAMQELRDNPA-LIPTAIEEILRWTSVVQWFARTATRDVEVGG
MLBr_02088|M.leprae_Br4923 LAMLRNPSQWKALSSNPQ-RAPLVVEETLRYDPAIHLIGRVAAKDMTIGQ
*: .::* :*: . *. :
MMAR_3761|M.marinum_M QLIRAGEKVVMFYASGNWDEDAFCHPERLDLSRSPNPHVGFGGGGVHFCL
MSMEG_4619|M.smegmatis_MC2_155 RQIAAGEKVVMFYASGNWDTTVFDRPDVLDLGRKPNPHLGFGGGGRHFCL
MAV_2174|M.avium_104 TKMKAGDKVALWYNSANRDESTFDNPWLFDVARTPNPHLGFGGGGAHFCL
MUL_1282|M.ulcerans_Agy99 TKMAAGDKVTLWYCSANRDEEKFADPWTFDVTRNPNPQVGFGGGGAHFCL
Mb0801|M.bovis_AF2122/97 QPIEAGQKVVVWEGSANRDPSVFDRADEFDITRKPNPHLGFG-QGVHYCL
Rv0778|M.tuberculosis_H37Rv QPIEAGQKVVVWEGSANRDPSVFDRADEFDITRKPNPHLGFG-QGVHYCL
Mflv_0425|M.gilvum_PYR-GCK IRLREGERVAMFYPSANRDEKHFADPDRFDIGRMPNPHLAFGGGGTHFCL
Mvan_0246|M.vanbaalenii_PYR-1 VPLRAGERVAMFYPSANRDEKHFADPDRFDIGRAPNHHLAFGGGGTHFCL
MAB_1211c|M.abscessus_ATCC_199 VRIRAGERVVMLYPSANFDEEVFENPHTFDITRDPNPHLGFGGTGAHYCL
TH_4556|M.thermoresistible__bu QRIAEGDKLVLWYGSGSRDEAVFENADTFDIHREKPNHMAFGGGGRHICL
MLBr_02088|M.leprae_Br4923 TTLTEGDTMVLLLAAANRDPAVYSRPDEFDPDRPSSRHLAFA-VGSHFCL
: *: :.: :.. * : . :* * ::.*. * * **
MMAR_3761|M.marinum_M GAHLARAQLRAIFGELLVQLPDIQA-GDPVYVPGNFVHAIRSMPCTF---
MSMEG_4619|M.smegmatis_MC2_155 GAHVARTQLRAIFGELLHQLPDIRA-GEPEYLQGNFVHAIRAMPCTFS--
MAV_2174|M.avium_104 GANLARREIRVVFDELRHEIPDIVATEEPARLLSQFIHGIKRLPVAWTPP
MUL_1282|M.ulcerans_Agy99 GANLARREIRVVFDELRRQMPDVVATEEPARLLSQFIHGIKRLPVAWSR-
Mb0801|M.bovis_AF2122/97 GANLARLELRVLFEELLSRFGSVRVVEPAEWTRSNRHTGIRHLVVELRGG
Rv0778|M.tuberculosis_H37Rv GANLARLELRVLFEELLSRFGSVRVVEPAEWTRSNRHTGIRHLVVELRGG
Mflv_0425|M.gilvum_PYR-GCK GASLARVEAAAIFRELITRTREIGLVGPVERVRSVLMNGIRSMPAQFTPA
Mvan_0246|M.vanbaalenii_PYR-1 GASLARVEATAIFGEILTRTAHIELAGPVERVRSVLMNGIRSMPVRLTPA
MAB_1211c|M.abscessus_ATCC_199 GANLAKAELEIIFNKIADRMPDISRIGDAPRFHSGWINGIKKFDTAYCPV
TH_4556|M.thermoresistible__bu GASLARLELRIVFEEVLSRMRDIRLAGTPELVPTHWVYGYSKMPITFTPG
MLBr_02088|M.leprae_Br4923 GAALARLEATVTLSAISARFPQVQLAGELVYKPNVAMRGMSALPVQV---
** :*: : : : . : . :
MMAR_3761|M.marinum_M -----
MSMEG_4619|M.smegmatis_MC2_155 -----
MAV_2174|M.avium_104 R----
MUL_1282|M.ulcerans_Agy99 -----
Mb0801|M.bovis_AF2122/97 -----
Rv0778|M.tuberculosis_H37Rv -----
Mflv_0425|M.gilvum_PYR-GCK VVPA-
Mvan_0246|M.vanbaalenii_PYR-1 SVPA-
MAB_1211c|M.abscessus_ATCC_199 TH---
TH_4556|M.thermoresistible__bu SKLGA
MLBr_02088|M.leprae_Br4923 -----