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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4132 | - | - | 100% (420) | putative cytochrome P450 |
| M. thermoresistible (build 8) | TH_4556 | - | e-165 | 67.41% (402) | PUTATIVE putative cytochrome P450 |
| M. thermoresistible (build 8) | TH_2649 | - | 4e-68 | 38.87% (391) | PUTATIVE cytochrome P450 superfamily protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0801 | cyp126 | 1e-67 | 38.54% (410) | cytochrome P450 126 |
| M. gilvum PYR-GCK | Mflv_0425 | - | 2e-79 | 41.12% (394) | cytochrome P450 |
| M. tuberculosis H37Rv | Rv0778 | cyp126 | 1e-67 | 38.54% (410) | cytochrome P450 126 |
| M. leprae Br4923 | MLBr_02088 | - | 8e-49 | 34.48% (319) | putative cytochrome p450 |
| M. abscessus ATCC 19977 | MAB_1211c | - | 3e-62 | 34.47% (409) | cytochrome P450 |
| M. marinum M | MMAR_3361 | cyp124A1 | 1e-67 | 38.21% (390) | cytochrome P450 124A1, Cyp124A1 |
| M. avium 104 | MAV_2174 | - | 2e-71 | 37.87% (404) | P450 heme-thiolate protein |
| M. smegmatis MC2 155 | MSMEG_4619 | - | 3e-69 | 40.95% (398) | putative cytochrome P450 126 |
| M. ulcerans Agy99 | MUL_1282 | cyp124A1 | 4e-68 | 38.46% (390) | cytochrome P450 124A1, Cyp124A1 |
| M. vanbaalenii PYR-1 | Mvan_0246 | - | 9e-81 | 40.85% (399) | cytochrome P450 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0801|M.bovis_AF2122/97 ---------------MTTAAGLS---GIDLTDLDNF--ADGFPHHLFAIH
Rv0778|M.tuberculosis_H37Rv ---------------MTTAAGLS---GIDLTDLDNF--ADGFPHHLFAIH
Mflv_0425|M.gilvum_PYR-GCK --------------MPADAITLG---GADLADPDTY--LAGMPYDAFRTL
Mvan_0246|M.vanbaalenii_PYR-1 --------------MATDAISIG---GVDLADPDTY--VGGMPHGAFREL
MAB_1211c|M.abscessus_ATCC_199 ------------MTAMKTAAELGLPEGFDFTDPELY--GNRMPHEEFATL
MMAR_3361|M.marinum_M MDLSTNLNTGLLPRVNGTPPPEVPLADIELGSLEFWGRDDDFRDGAFATL
MUL_1282|M.ulcerans_Agy99 MDLSTNLNTGLLPRVNGTPPPEVPLADIELGSLEFWGRDDDFRDGAFATL
MAV_2174|M.avium_104 MSLKTRPKKGLATRINGAPPPRVPLADIHLESLDFWGYDDDFRDGAFATL
MSMEG_4619|M.smegmatis_MC2_155 ---------------MTVLPITRPYDAVDLSSRAFWATTAADREVAFAQL
TH_4132|M.thermoresistible__bu ------------MTVQPVTDTTWDVKHVNVFDPQWWVDGP--PHDLFKRM
MLBr_02088|M.leprae_Br4923 -----MRTCVPTRTCVYAFIEYLSHNRPMGTNPPSLVEAQMLLLRLIDPG
. :
Mb0801|M.bovis_AF2122/97 RREAPVYWHRPTEHTP--DGE--GFWSVATYAETLEVLRDPVTYSSVTGG
Rv0778|M.tuberculosis_H37Rv RREAPVYWHRPTEHTP--DGE--GFWSVATYAETLEVLRDPVTYSSVTGG
Mflv_0425|M.gilvum_PYR-GCK RREAPVAWHPQV------DKP--GFWALTGYDEIYAVSRDSETWSSQATG
Mvan_0246|M.vanbaalenii_PYR-1 RRHAPVAWHPYG------DNP--GFWALTGYDEVLAVSRDSRTWSSQTTG
MAB_1211c|M.abscessus_ATCC_199 RREAPVWWNPQPRTVGGFADE--GYWVISKHRDVREVSLHTDTFSSGRKG
MMAR_3361|M.marinum_M RREAPISFWPPIELAGLTAG--KGHWALTKHDDIHFASRHPEIFHS-SPN
MUL_1282|M.ulcerans_Agy99 RREAPISFWPPIELAGLTAG--KGHWALTKHDDIHFASRHPEIFHS-SPN
MAV_2174|M.avium_104 RREAPISFWPAIEMDGFVAG--NGYWALTKHEDVHFASRHPEIFSS-VPN
MSMEG_4619|M.smegmatis_MC2_155 RAERPVSWHPPVEDALMHDPDDKGFWAVTRHADIVAISRDSETFLS-GQG
TH_4132|M.thermoresistible__bu RAESPVHWYQFADGEGYGPG----YWSLFRHADIATVSHDTETFSS-NRG
MLBr_02088|M.leprae_Br4923 TRADPFPVYRALIDYGPMQLPGMPLTVFSSFSDCDEALRHPLSASDRLKA
*. . . : .. .
Mb0801|M.bovis_AF2122/97 QR-RFGGTVLQD-LPVAGQVLNMMDDPRHTRIRRLVSSGLTPRMIRRVED
Rv0778|M.tuberculosis_H37Rv QR-RFGGTVLQD-LPVAGQVLNMMDDPRHTRIRRLVSSGLTPRMIRRVED
Mflv_0425|M.gilvum_PYR-GCK VF--LDVPAPEDSYQLALMMLT-MDPPRHTALRALVSRGFTPRHVARLGA
Mvan_0246|M.vanbaalenii_PYR-1 VF--LDVPAPEDSYQLSLMMLT-MDPPRHTALRALVSRGFTPRHLARLNA
MAB_1211c|M.abscessus_ATCC_199 AIPRLEDHISPEEFQATLSVLINKDAPEHTQLRGLVSRMFTPRSIAALRI
MMAR_3361|M.marinum_M ----IVIHDQTPELAEYFGSMIVLDDPRHQRLRSIVSRAFTPKVVARIEA
MUL_1282|M.ulcerans_Agy99 ----IVIHDQTPELAEYFGSMIVLDDPRHQRLRSIVSRAFTPKVVARIEA
MAV_2174|M.avium_104 ----ITINDQTPELAEYFGSMIVLDDPRHQRLRSIVSRAFTPKVVARIEA
MSMEG_4619|M.smegmatis_MC2_155 ----VLFENVPQELLEASQSFLAMDAPRHTLIRKLVHSAFTPRQVARIED
TH_4132|M.thermoresistible__bu GL--FIHPDQMLSLDVLTNMLNFMDPPTHTRYRKILARVFTPAAVAKMED
MLBr_02088|M.leprae_Br4923 TLAQQAIAAGAEPRPFYASSFMFLDPPDHTRLRKLVSKAFAPKVVQALEG
: * * * * :: ::* : :
Mb0801|M.bovis_AF2122/97 DLRRRARGLLDGVEPGAPF---DFVVEIAAELPMQMICILLGVPETDRHW
Rv0778|M.tuberculosis_H37Rv DLRRRARGLLDGVEPGAPF---DFVVEIAAELPMQMICILLGVPETDRHW
Mflv_0425|M.gilvum_PYR-GCK RTADMARAIVDDALAHGQC---EFVDEVAGALPSYVIAELLGIPLEDGRR
Mvan_0246|M.vanbaalenii_PYR-1 RTADMARDILDAALQRGEC---EFVDDVAGALPSYVIAELLGIPLDDGRR
MAB_1211c|M.abscessus_ATCC_199 TLEERAERIVRAALEGGHG---EFVREVASELPMQAIAELIGVPEEDRVK
MMAR_3361|M.marinum_M SVRERAHRLVAAMIENHPDGQADLVSELAGPLPLQIICDMMGIPEEDHEQ
MUL_1282|M.ulcerans_Agy99 SVRERAHRLVAAMIENHPDGQADLVSELAGPLPLQIICDMMGIPEEDHEQ
MAV_2174|M.avium_104 SVRERARRLVSSLVANHPNGEAELVSELAGPLPLQVICDMMGIPEEDHQR
MSMEG_4619|M.smegmatis_MC2_155 SIKANAAAIVAELKAAGSG--VDFVDHCAKELPIRTLSDMVGIPEGEREK
TH_4132|M.thermoresistible__bu GIRARVNRIIDKVIEAGRC---DFVEDIAVPIPLGILMELMGAPEEDMPK
MLBr_02088|M.leprae_Br4923 DIAALVDSLLDKGAAAGQF---DVIADLAFPLAVAVICRLLGVPYEDAPE
. :: :.: . * :. : ::* * :
Mb0801|M.bovis_AF2122/97 LFEAVEPGFDFRGSRRATM-----PRLNVEDAGSRLYTYALELIAGKRAE
Rv0778|M.tuberculosis_H37Rv LFEAVEPGFDFRGSRRATM-----PRLNVEDAGSRLYTYALELIAGKRAE
Mflv_0425|M.gilvum_PYR-GCK LYTLTD----IMNTRPLHD-----PELVA--AQMQMFEYAAELAARKRSE
Mvan_0246|M.vanbaalenii_PYR-1 LYALTE----IMNTRPLHD-----PELMQ--TQVELFGYAGDLAASKRAA
MAB_1211c|M.abscessus_ATCC_199 LFEWSN----QMTGYDEAD-----VEIDPRVGAAQILGYSYQLAEQRRDC
MMAR_3361|M.marinum_M IFHWTNVILG-FGDPDLTT-----DFDEFLQVSMAIGGYATALADDRRVN
MUL_1282|M.ulcerans_Agy99 IFHWTNVILG-FGDPDLTT-----DFDDFLQVSMAIGGYATALADDRRVN
MAV_2174|M.avium_104 VFHWTNVILG-FGDPDLAT-----DFEEFLQVSMDIGAYATALAEDRRVN
MSMEG_4619|M.smegmatis_MC2_155 VAHAADALVS-WADPIYLAGR--HPLEVLLENQMYLHQVANTLAAERREN
TH_4132|M.thermoresistible__bu FYYWTEAIEQAIRDPEPNT-----GVEVFDEMGAYLTEQIERQTTEAVED
MLBr_02088|M.leprae_Br4923 FGRVSALLVQSVDPFITITGEPPEATEERLRAGVWLRDYLEQLVKCRRGT
. :
Mb0801|M.bovis_AF2122/97 PADDMLSVVANATIDDPDAPALSDAELYLFFHLLFSAGAETTRNSIAGGL
Rv0778|M.tuberculosis_H37Rv PADDMLSVVANATIDDPDAPALSDAELYLFFHLLFSAGAETTRNSIAGGL
Mflv_0425|M.gilvum_PYR-GCK PGDDIATALLHAEVD---GRRLTDLEFNLFFLLLINAGGDTTRNLVAAGT
Mvan_0246|M.vanbaalenii_PYR-1 PGDDIATALLHAEVD---GQRLTDLEFNLFFMLLLNAGGDTTRNLVAAGT
MAB_1211c|M.abscessus_ATCC_199 PGNDVVSRLLTGTVD---GEQLTPEQFGFFVVMLSVAGNETTRNATTMGM
MMAR_3361|M.marinum_M HHGDLTTSLVEAEVD---GERLSSSEIAMFFILLVVAGNETTRNAISHGM
MUL_1282|M.ulcerans_Agy99 HHGDLTTSLVEAEVD---GERLSSSEIAMFFILLVVAGNETTRNTISHGM
MAV_2174|M.avium_104 HHDDLTTSLVEAEVD---GERLTSSEIASFFILLVVAGNETTRNAISHGV
MSMEG_4619|M.smegmatis_MC2_155 PGNDLISALVHAEVD---GDRLTDAEVAAFFVLLAVAGNDTTRQTTSHAL
TH_4132|M.thermoresistible__bu S---LVMRLRNAEVD---GEKLTDVEIVMFFGLLTFAGNDTTRNTASAGL
MLBr_02088|M.leprae_Br4923 PGEDLISRLIELDES---GDQLTEEEIIATCGLLLVAGHETTVNLIANAV
: : . . *: :. :* ** :** : : .
Mb0801|M.bovis_AF2122/97 LALAENPDQLQTLRSDFE-LLPTAIEEIVRWTSPSPSKRRTASRAVSLGG
Rv0778|M.tuberculosis_H37Rv LALAENPDQLQTLRSDFE-LLPTAIEEIVRWTSPSPSKRRTASRAVSLGG
Mflv_0425|M.gilvum_PYR-GCK LALIEHPDQWRRLAADPS-LMPTAVEEMLRWTSPVTVFSRTATRDTDVGG
Mvan_0246|M.vanbaalenii_PYR-1 LALIEHPEQWARLAADPS-LMPTAIEEMLRWTSPVNVFTRTATRDTEVGG
MAB_1211c|M.abscessus_ATCC_199 MAFLEHPGQWELFKSAR---PSTTVDEIVRYTSPLISQQRTALQDTVISD
MMAR_3361|M.marinum_M LALSRYPDERAKWWSDFDGLAATAVEEIVRWASPVVYMRRTLSQDVDLRG
MUL_1282|M.ulcerans_Agy99 LALSRYPDERAKWWSDFDGLAATAVEEIVRWASPVVYMRRTLNQDVDLRG
MAV_2174|M.avium_104 LALSRYPDERDKWFSDFDRLTPTAVEEVVRWASPVVYMRRTLTRDVKLRG
MSMEG_4619|M.smegmatis_MC2_155 KALTDFEDQRAWLMEDFDDRIGVAVEEMVRWASPVMTFRRTAAVDVELGG
TH_4132|M.thermoresistible__bu RTLLEHPDALQQLYDDAA-LIPNAIEEILRYTSVVQWFARTATRDVELGG
MLBr_02088|M.leprae_Br4923 LAMLRNPSQWKALSSNPQ-RAPLVVEETLRYDPAIHLIGRVAAKDMTIGQ
:: .::* :*: . *. :
Mb0801|M.bovis_AF2122/97 QPIEAGQKVVVWEGSANRDPSVFDRADEFDITRKPNPHLGFG-QGVHYCL
Rv0778|M.tuberculosis_H37Rv QPIEAGQKVVVWEGSANRDPSVFDRADEFDITRKPNPHLGFG-QGVHYCL
Mflv_0425|M.gilvum_PYR-GCK IRLREGERVAMFYPSANRDEKHFADPDRFDIGRMPNPHLAFGGGGTHFCL
Mvan_0246|M.vanbaalenii_PYR-1 VPLRAGERVAMFYPSANRDEKHFADPDRFDIGRAPNHHLAFGGGGTHFCL
MAB_1211c|M.abscessus_ATCC_199 VRIRAGERVVMLYPSANFDEEVFENPHTFDITRDPNPHLGFGGTGAHYCL
MMAR_3361|M.marinum_M TKMAAGDKVTLWYCSANRDEEKFADPWTFDVTRNPNPQVGFGGGGAHFCL
MUL_1282|M.ulcerans_Agy99 TKMAAGDKVTLWYCSANRDEEKFADPWTFDVTRNPNPQVGFGGGGAHFCL
MAV_2174|M.avium_104 TKMKAGDKVALWYNSANRDESTFDNPWLFDVARTPNPHLGFGGGGAHFCL
MSMEG_4619|M.smegmatis_MC2_155 RQIAAGEKVVMFYASGNWDTTVFDRPDVLDLGRKPNPHLGFGGGGRHFCL
TH_4132|M.thermoresistible__bu QKISEGDKVVMWYASGSRDEAVFDDSDTFDIHRPKPDHQAFGGGGRHFCL
MLBr_02088|M.leprae_Br4923 TTLTEGDTMVLLLAAANRDPAVYSRPDEFDPDRPSSRHLAFA-VGSHFCL
: *: :.: :.. * : . :* * : .*. * *:**
Mb0801|M.bovis_AF2122/97 GANLARLELRVLFEELLSRFGSVRVVEPAEWTRSNRHTGIRHLVVELRGG
Rv0778|M.tuberculosis_H37Rv GANLARLELRVLFEELLSRFGSVRVVEPAEWTRSNRHTGIRHLVVELRGG
Mflv_0425|M.gilvum_PYR-GCK GASLARVEAAAIFRELITRTREIGLVGPVERVRSVLMNGIRSMPAQFTPA
Mvan_0246|M.vanbaalenii_PYR-1 GASLARVEATAIFGEILTRTAHIELAGPVERVRSVLMNGIRSMPVRLTPA
MAB_1211c|M.abscessus_ATCC_199 GANLAKAELEIIFNKIADRMPDISRIGDAPRFHSGWINGIKKFDTAYCPV
MMAR_3361|M.marinum_M GANLARREIRVVFDELRRQMPDVVATEEPARLLSQFIHGIKRLPVAWSR-
MUL_1282|M.ulcerans_Agy99 GANLARREIRVVFDELRRQMPDVVATEEPARLLSQFIHGIKRLPVAWSR-
MAV_2174|M.avium_104 GANLARREIRVVFDELRHEIPDIVATEEPARLLSQFIHGIKRLPVAWTPP
MSMEG_4619|M.smegmatis_MC2_155 GAHVARTQLRAIFGELLHQLPDIRA-GEPEYLQGNFVHAIRAMPCTFS--
TH_4132|M.thermoresistible__bu GASLARLELRIIFEEVLGRMKNLQLAGTTEILPSNWAYGLTKLPVTFTAG
MLBr_02088|M.leprae_Br4923 GAALARLEATVTLSAISARFPQVQLAGELVYKPNVAMRGMSALPVQV---
** :*: : : : . : . .: :
Mb0801|M.bovis_AF2122/97 -----
Rv0778|M.tuberculosis_H37Rv -----
Mflv_0425|M.gilvum_PYR-GCK VVPA-
Mvan_0246|M.vanbaalenii_PYR-1 SVPA-
MAB_1211c|M.abscessus_ATCC_199 TH---
MMAR_3361|M.marinum_M -----
MUL_1282|M.ulcerans_Agy99 -----
MAV_2174|M.avium_104 R----
MSMEG_4619|M.smegmatis_MC2_155 -----
TH_4132|M.thermoresistible__bu RRLES
MLBr_02088|M.leprae_Br4923 -----