For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_1263 | - | 100% (436) | PROBABLE CYTOCHROME P450 125 CYP125 | |
| M. thermoresistible (build 8) | TH_1956 | - | e-134 | 57.57% (403) | PROBABLE CYTOCHROME P450 125 CYP125 |
| M. thermoresistible (build 8) | TH_0362 | - | e-134 | 55.06% (405) | PROBABLE CYTOCHROME P450 125 CYP125 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3575c | cyp125 | 1e-133 | 56.16% (406) | cytochrome P450 125 |
| M. gilvum PYR-GCK | Mflv_1607 | - | 0.0 | 78.50% (400) | cytochrome P450 |
| M. tuberculosis H37Rv | Rv3545c | cyp125 | 1e-133 | 56.16% (406) | cytochrome P450 125 |
| M. leprae Br4923 | MLBr_02088 | - | 2e-43 | 31.96% (341) | putative cytochrome p450 |
| M. abscessus ATCC 19977 | MAB_0613 | - | 1e-129 | 53.45% (406) | putative cytochrome P450 |
| M. marinum M | MMAR_2783 | cyp125A6 | 1e-133 | 56.82% (403) | cytochrome P450 125A6 Cyp125A6 |
| M. avium 104 | MAV_0616 | - | 1e-138 | 57.78% (405) | putative cytochrome P450 124 |
| M. smegmatis MC2 155 | MSMEG_5853 | - | 0.0 | 82.06% (407) | cytochrome P450 |
| M. ulcerans Agy99 | MUL_4106 | cyp125A7 | 1e-131 | 54.68% (406) | cytochrome P450 125A7 Cyp125A7 |
| M. vanbaalenii PYR-1 | Mvan_5151 | - | 0.0 | 77.94% (417) | cytochrome P450 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3575c|M.bovis_AF2122/97 ----------MSWNHQSVEIAVRRTTVPSPNLPPGFDFTDPAIYAERLPV
Rv3545c|M.tuberculosis_H37Rv ----------MSWNHQSVEIAVRRTTVPSPNLPPGFDFTDPAIYAERLPV
MUL_4106|M.ulcerans_Agy99 --------------------------MPCPNLPPGFDFTDPDIYAERLPV
MAV_0616|M.avium_104 --------------------------MPSPNLPPGFDLLDPDVCVKGLPV
MAB_0613|M.abscessus_ATCC_1997 --------------------------MVHPSLPAGFDFTDPEIYAERLPV
MMAR_2783|M.marinum_M ------------------MPAAEPTATSVPNLPPGFDFTDPDIYAERLPV
TH_1263|M.thermoresistible__bu MVGVERVPCHTKEVVAMSAAHSSPALGQSPFG-AGFDFTDPDVLLRGIPV
MSMEG_5853|M.smegmatis_MC2_155 ----------------------MATMNTCPFG-NGYDFTDPDVLFRGIPV
Mflv_1607|M.gilvum_PYR-GCK ----------------MTAED--ARVQSCPFLPDGYDFTDPDVLLEGVPV
Mvan_5151|M.vanbaalenii_PYR-1 ----------------MTAT------QSCPFLPHGYDFTDPDVLLKGIPV
MLBr_02088|M.leprae_Br4923 ------------MRTCVPTRTCVYAFIEYLSHNRPMGTNPPSLVEAQMLL
. * : : :
Mb3575c|M.bovis_AF2122/97 AEFAELRSAAP--IWWNGQDPGKGGGFHDGGFWAITKLNDVKEISRHS-D
Rv3545c|M.tuberculosis_H37Rv AEFAELRSAAP--IWWNGQDPGKGGGFHDGGFWAITKLNDVKEISRHS-D
MUL_4106|M.ulcerans_Agy99 EEFAELRSSEP--IWWDEQFPGQGGGFHDGGFWAITKLKDVKEVSRRS-D
MAV_0616|M.avium_104 AELAELRKSAP--IYWMD-VPGGTGGFGDKGYWAITKHKDVKEISVRS-D
MAB_0613|M.abscessus_ATCC_1997 EELKELRKTAP--IWWQE-QPDGVGGFNDGGYWVVTKHKDVKEVSLRS-D
MMAR_2783|M.marinum_M AELAEMRRSAP--IWWNE-QPTGCGGFDDGGFWVVTKHKDVKEISLRS-D
TH_1263|M.thermoresistible__bu REFAELRKTAP--VWWCE---QPETIFGDTGYWVISRHEDIKNISRNS-D
MSMEG_5853|M.smegmatis_MC2_155 EEFAVLRKTAP--VWWNQ---QGESIFDDGGYWVISRHEDIKTISRDGGE
Mflv_1607|M.gilvum_PYR-GCK AEFAQLRRTAP--VWWNA---QQESIFDDGGYWVVSRHEDIKSISRNS-A
Mvan_5151|M.vanbaalenii_PYR-1 TEFAELRRTAP--VWWNE---QADSIFDDGGYWVISRHEDVKAISRNS-T
MLBr_02088|M.leprae_Br4923 LRLIDPGTRADPFPVYRALIDYGPMQLPGMPLTVFSSFSDCDEALRHP-L
.: : : . ..: .* .
Mb3575c|M.bovis_AF2122/97 VFSSYENGVIPRFKNDIAREDIEVQRFVMLNMDAPHHTRLRKIISRGFTP
Rv3545c|M.tuberculosis_H37Rv VFSSYENGVIPRFKNDIAREDIEVQRFVMLNMDAPHHTRLRKIISRGFTP
MUL_4106|M.ulcerans_Agy99 VFSSYENGVIPRFKNDIAREDIDVQRFVMLNMDAPHHTRLRKIISRGFTP
MAV_0616|M.avium_104 IFSSQQDCAIPVWPKEMTREQIDLQRNVMLNMDAPHHTRLRKIISRGFTP
MAB_0613|M.abscessus_ATCC_1997 VFSSWENTAIPRFQDDITREAIELQRYVMLNMDAPHHTRLRKIISRGFTP
MMAR_2783|M.marinum_M VFSSLQKTALPRYKDGTVDEQIERGKFVLLNMDAPQHTRLRKIVSRAFTP
TH_1263|M.thermoresistible__bu LWSTNRKGAVMVMPEGATPEQLELTKALLINHDPPEHTRLRKLVSRLFTP
MSMEG_5853|M.smegmatis_MC2_155 VWSTNAKGAVMRLPDGVTAEQLDLTKALLINHDAPEHTRLRKLVSRLFTP
Mflv_1607|M.gilvum_PYR-GCK LWSTNAKGAVMRLPDGVTAEQLDLTKALLINHDAPEHTRLRKIVSRLFTP
Mvan_5151|M.vanbaalenii_PYR-1 QWSTNTKGAVMRLPDGVTAEQLDLTKALLINHDAPEHTRLRKIVSRLFTP
MLBr_02088|M.leprae_Br4923 SASDRLKATLAQQAIAAGAEPRPFYASSFMFLDPPDHTRLRKLVSKAFAP
* . .: * :: *.*.******::*: *:*
Mb3575c|M.bovis_AF2122/97 RAVGRLHDELQERAQKIAAEAAAAGSGDFVEQVSCELPLQAIAGLLGVPQ
Rv3545c|M.tuberculosis_H37Rv RAVGRLHDELQERAQKIAAEAAAAGSGDFVEQVSCELPLQAIAGLLGVPQ
MUL_4106|M.ulcerans_Agy99 RAIGRLHDELNDRAQNIAKAAAAAGSGDFVEQVSCELPLQAIAGLLGIPQ
MAV_0616|M.avium_104 RAVGRLRDELDARAQNIAKTAAAAGAGDFVEQVSCELPLQAIAGLLGVPQ
MAB_0613|M.abscessus_ATCC_1997 RAIGRLRDELNERAQEIAKAAAASGTGDFVEQVSCELPLQAIAGLLGVPI
MMAR_2783|M.marinum_M RAVERLRDDLRERARRIVEAAAAEGRGDFVEQVSCELPLQAIAGLMGVPQ
TH_1263|M.thermoresistible__bu RAVAELESKLAVAARDIVARARERGSGNFVEDIAMNLPLLAIADLIGVPE
MSMEG_5853|M.smegmatis_MC2_155 RSVAALEEKLAVAAHDIVAEAKAEGSGNFVEDIAMKLPLLAIADLIGVPE
Mflv_1607|M.gilvum_PYR-GCK RAIAGMEAKLADSARQIVGEAADKAGGNFVDDVATLLPLQAIADLIGVPE
Mvan_5151|M.vanbaalenii_PYR-1 RAIAGMEDRLADAAREIVRSAAEKDSGDFVDDVAMMLPLQAIADLIGVPE
MLBr_02088|M.leprae_Br4923 KVVQALEGDIAALVDSLLDKGAAAGQFDVIADLAFPLAVAVICRLLGVPY
: : :. : . : . :.: ::: *.: .*. *:*:*
Mb3575c|M.bovis_AF2122/97 EDRGKLFHWSNEMTG--------NEDPEYAHIDPKASSAELIGYAMKMAE
Rv3545c|M.tuberculosis_H37Rv EDRGKLFHWSNEMTG--------NEDPEYAHIDPKASSAELIGYAMKMAE
MUL_4106|M.ulcerans_Agy99 EDRGKLFDWSNEMTG--------TEDPEFAHIDAKASSVELIGYAMKMAE
MAV_0616|M.avium_104 EDRDKIFRWSNEMTG--------NEDPEYAHIDPAMSSAELIMYAMKMAE
MAB_0613|M.abscessus_ATCC_1997 EDRGKLFNWSNEMTS--------YDDPEYADIDPAASSMEILAYSMEMAK
MMAR_2783|M.marinum_M EDRKKLFHWSNEMVG--------DQDPEFATNDALTASVELIMYGMQMAA
TH_1263|M.thermoresistible__bu EDREKVFHWSNCIIN--------TDDPDFD-SDPTAANAELMGYAYTMAE
MSMEG_5853|M.smegmatis_MC2_155 ADREKIFAWSNAIIN--------TDDPDFD-SDPTVANAELMGYAYTMAE
Mflv_1607|M.gilvum_PYR-GCK EDREKLFHWSNAIMN--------TDDPDFD-SDPTIANAELMGYAYTMAE
Mvan_5151|M.vanbaalenii_PYR-1 EDREKLFHWTNAIMN--------TDDPEFD-ADPTMANAELMGYAYSMAE
MLBr_02088|M.leprae_Br4923 EDAPEFGRVSALLVQSVDPFITITGEPPEATEERLRAGVWLRDYLEQLVK
* :. : : :* : :. : * :.
Mb3575c|M.bovis_AF2122/97 EKAKNPADDIVTQLIQADID--GE-KLSDDEFGFFVVMLAVAGNETTRNS
Rv3545c|M.tuberculosis_H37Rv EKAKNPADDIVTQLIQADID--GE-KLSDDEFGFFVVMLAVAGNETTRNS
MUL_4106|M.ulcerans_Agy99 EKAKNPGDDIVTQLIQADID--GE-KLSDDEFGFFVVMLAVAGNETTRNS
MAV_0616|M.avium_104 ERAKNPGDDIVTQLIQADLD--GE-KLSDDEFGFFVVMLAVAGNETTRNS
MAB_0613|M.abscessus_ATCC_1997 QKAENPGEDIVTTLINAEVE--GEGKLSDDEFGFFVIMLAVAGNETSRNS
MMAR_2783|M.marinum_M DRAKNPGQDLVTKLVEADID--GH-KLSDDEFGFFVILLAVAGNETTRNS
TH_1263|M.thermoresistible__bu QRRRHPQDDIVTRLVQADLEDGSGEALGEVEFAFFVILLAVAGNETTRNA
MSMEG_5853|M.smegmatis_MC2_155 ERRRCPADDIVTRLVQADV---SGESLGEVEFAFFVILLAVAGNETTRNA
Mflv_1607|M.gilvum_PYR-GCK QRRRCPADDIVTRLVEADLD---GDALGEVEFAFFVILLAVAGNETTRNA
Mvan_5151|M.vanbaalenii_PYR-1 ERRRCPADDIVTRLVQADID---GESLGEVEFAFFVILLAVAGNETTRNA
MLBr_02088|M.leprae_Br4923 CRRGTPGEDLISRLIELDES---GDQLTEEEIIATCGLLLVAGHETTVNL
: * :*::: *:: : * : *: :* ***:**: *
Mb3575c|M.bovis_AF2122/97 ITQGMMAFAEHPDQWELYKK--VRPETAADEIVRWATPVTAFQRTALRDY
Rv3545c|M.tuberculosis_H37Rv ITQGMMAFAEHPDQWELYKK--VRPETAADEIVRWATPVTAFQRTALRDY
MUL_4106|M.ulcerans_Agy99 ITQGMMAFADNPEQWELYKR--ERPGTAADEIVRWATPVTSFQRTALEDY
MAV_0616|M.avium_104 ITHGMIAFADNPDQWELFKK--ERPETAPDEIVRWATPVTAFQRTALEDY
MAB_0613|M.abscessus_ATCC_1997 ITQGMMAFTQFPEQWELYKK--ERPETAADEIVRWATPVTSFQRTALEDT
MMAR_2783|M.marinum_M ITQGMMAFTDFPDQWELYKR--ERPVTTADEIVRWATPVTSFQRTALQDY
TH_1263|M.thermoresistible__bu MTHGMNAFFENPDQWELFKR--ERPETAIDEIVRWSTPVHCFQRTALADV
MSMEG_5853|M.smegmatis_MC2_155 ITHGMNAFFENPDQWELFKR--ERPITAVDEIVRWATPVHCFQRTAVVDT
Mflv_1607|M.gilvum_PYR-GCK MTHGMNAFLDHPDQWELFKR--ERPETAIDEIIRWATPVHCFQRTALDDV
Mvan_5151|M.vanbaalenii_PYR-1 MTHGMNAFFDNPAQWELFKR--ERPETAIDEIIRWATPVHCFQRTALEDV
MLBr_02088|M.leprae_Br4923 IANAVLAMLRNPSQWKALSSNPQRAPLVVEETLRYDPAIHLIGRVAAKDM
:::.: *: * **: . *. . :* :*: ..: : *.* *
Mb3575c|M.bovis_AF2122/97 ELSGVQIKKGQRVVMFYRSANFDEEVFQDPFTFNILRNPNPHVGFGGTGA
Rv3545c|M.tuberculosis_H37Rv ELSGVQIKKGQRVVMFYRSANFDEEVFQDPFTFNILRNPNPHVGFGGTGA
MUL_4106|M.ulcerans_Agy99 ELSGVQIKKGQRVLMFYRSANFDEEVFEDPFSFNILRNPNPHVGFGGTGA
MAV_0616|M.avium_104 ELSGVQIKKGQRVVMFYRSANFDEEVFEDPHRFNILRNPNPHVGFGGTGA
MAB_0613|M.abscessus_ATCC_1997 ELDGVKIKKGQRVVMMYRSANFDEDVFEDPFSFNIMRNPNPHMGFGGSGA
MMAR_2783|M.marinum_M ELSGVRIKKGQRVVMFYRSANFDEDVFDDPYTFNILRDPNPHVGFGGTGA
TH_1263|M.thermoresistible__bu EIGGVTIREGERAGLFYSSANYDEEVFDRPFEFDILRDPNPHLGFGGHGA
MSMEG_5853|M.smegmatis_MC2_155 EIGGVPIKAGQRAGLFYSSANYDEDVFDDPFRFDILRDPNPHLGFGGNGA
Mflv_1607|M.gilvum_PYR-GCK EIGGVTVARGQRVGLFYSSANFDEDVFDNPFNFDILRNPNPHLAFGGNGA
Mvan_5151|M.vanbaalenii_PYR-1 EVGGVTIAEGQRVGLFYSSANFDEDVFDRPFDFDILRDPNPHLAFGGNGA
MLBr_02088|M.leprae_Br4923 TIGQTTLTEGDTMVLLLAAANRDPAVYSRPDEFDPDRPSSRHLAFA-VGS
:. . : *: :: :** * *:. * *: * .. *:.*. *:
Mb3575c|M.bovis_AF2122/97 HYCIGANLARMTINLIFNAVADHMPDLKPISAPERLRSGWLNGIKHWQVD
Rv3545c|M.tuberculosis_H37Rv HYCIGANLARMTINLIFNAVADHMPDLKPISAPERLRSGWLNGIKHWQVD
MUL_4106|M.ulcerans_Agy99 HYCIGANLARMTINLIFNAVADHMPDLKPIAAPERLRSGWLNGIKHWQVD
MAV_0616|M.avium_104 HYCIGANLARMTISLIFNAVADHMPDLKPLSAPERLRSGWLNGIKHWQVD
MAB_0613|M.abscessus_ATCC_1997 HYCIGANLARLTINLMFNAIADHMPNLAPAGDPKRLQSGWLNGIKHWQVD
MMAR_2783|M.marinum_M HYCIGANLARMTIDLMFNAIADVMPDLESISQPERLRSGWLNGIKHWQVD
TH_1263|M.thermoresistible__bu HYCIGANLARMEIKLIFNEIADQIPDIAKLSEPVRLRSGWLNGVKELRVS
MSMEG_5853|M.smegmatis_MC2_155 HYCIGANLARMEIRLMFDEIADQIPDITKVGEPQRLRSGWINGVKDLQVS
Mflv_1607|M.gilvum_PYR-GCK HYCIGANLARMEIKLMFEAIADRLPDISKRAEPQRLRSGWINGVKDLQVA
Mvan_5151|M.vanbaalenii_PYR-1 HFCIGANLARMEIKLMFNEIADQIPDISKLAEPQRLRSGWINGVKNLQVA
MLBr_02088|M.leprae_Br4923 HFCLGAALARLEATVTLSAISARFPQVQLAGELVYKPNVAMRGMSALPVQ
*:*:** ***: : :. :: :*:: . . :.*:. *
Mb3575c|M.bovis_AF2122/97 YTGR----CPVAH
Rv3545c|M.tuberculosis_H37Rv YTGR----CPVAH
MUL_4106|M.ulcerans_Agy99 YTGK----CPVSH
MAV_0616|M.avium_104 YTGK----CPVAH
MAB_0613|M.abscessus_ATCC_1997 FTGASG--CPVLQ
MMAR_2783|M.marinum_M YHSDSSGKCPVAH
TH_1263|M.thermoresistible__bu YVG----------
MSMEG_5853|M.smegmatis_MC2_155 YRG----------
Mflv_1607|M.gilvum_PYR-GCK YR-----------
Mvan_5151|M.vanbaalenii_PYR-1 YR-----------
MLBr_02088|M.leprae_Br4923 V------------