For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_4372 (-)

annotation: Integrase, catalytic region
coordinates: 3928436 - 3929332
length: 299

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4372--100% (299)Integrase, catalytic region
M. thermoresistible (build 8)TH_3162-1e-5851.10% (227) PUTATIVE Integrase, catalytic region
M. thermoresistible (build 8)TH_3317-2e-2426.37% (292) PUTATIVE Integrase, catalytic region

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2838c-1e-2929.02% (255) transposase
M. gilvum PYR-GCKMflv_4642-2e-4035.69% (269) integrase catalytic subunit
M. tuberculosis H37RvRv3475-6e-3029.03% (279) transposase IS6110
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2088-4e-2830.86% (269) transposase
M. marinum MMMAR_3786-8e-3333.94% (277) transposase
M. avium 104MAV_5037-1e-3234.05% (232) transposase
M. smegmatis MC2 155MSMEG_1249-4e-3332.48% (274) ISMsm7, transposase orfB
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_5060-1e-14985.62% (292) integrase catalytic subunit

CLUSTAL 2.0.9 multiple sequence alignment


TH_4372|M.thermoresistible__bu      --------------------------------------VSRFELIAAECA
Mvan_5060|M.vanbaalenii_PYR-1       --------------------------------------MSRFELIAAECA
Mflv_4642|M.gilvum_PYR-GCK          -------------------------------------MSQKYAFIAAEHA
MAB_2088|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_1249|M.smegmatis_MC2_155      ---------------------------------------MMYPLVLDLAA
MMAR_3786|M.marinum_M               --------------------------------MPRQYSSSVRRQIVSRLR
Mb2838c|M.bovis_AF2122/97           --------------------------------------------------
Rv3475|M.tuberculosis_H37Rv         AEALAAGQRRIAKGERDFKDRVGFLRGRARPASTLITRFIADHQGHREGP
MAV_5037|M.avium_104                --------------------------------------------------
                                                                                      

TH_4372|M.thermoresistible__bu      H--------HDVSKLAELLGVSRSGYYAWAARQRRVELS-----------
Mvan_5060|M.vanbaalenii_PYR-1       D--------HDIATLTELLGVSRSGYYAWEARQRRTEPT-----------
Mflv_4642|M.gilvum_PYR-GCK          DGATFAGMAPTIVQMLKWLGVSKSGFYEWWGRPASAAMC-----------
MAB_2088|M.abscessus_ATCC_1997      -------------MTRRVLKLARQPYYRWRANPITDA-------------
MSMEG_1249|M.smegmatis_MC2_155      DG-------VPVTVTCRVLGFSTQAFYRWRKAPVSQR-------------
MMAR_3786|M.marinum_M               VG-------EPVAVVAAETGVCQATLFRWKRQALIDAGVIEGTPSVEADE
Mb2838c|M.bovis_AF2122/97           ------------------MPIAPSTYYDHINREPSRRELR----------
Rv3475|M.tuberculosis_H37Rv         DGLRWGVESICTQLTELGVPIAPSTYYDHINREPSRRELR----------
MAV_5037|M.avium_104                --------------------MALSTYYDTKARVPSARALR----------
                                                        ..    :                       

TH_4372|M.thermoresistible__bu      ----------PRQQWRRDLEVKILAHWQASGRTYGSPRITADLHAEGVGV
Mvan_5060|M.vanbaalenii_PYR-1       ----------ARQQWRRDLEVKILAHWKESKRTYGSPRITADLHAAGVSV
Mflv_4642|M.gilvum_PYR-GCK          ----------RRE----ELKLKIAALFTSFGAVYGYRRIHAELVRAGERV
MAB_2088|M.abscessus_ATCC_1997      -------------ELVEAYRANALFDAHGEDPEFGYRYLVEEAREAGEPM
MSMEG_1249|M.smegmatis_MC2_155      -------------DWDDAHLINAARNIHADDPAFGYRFIADELPAHGITA
MMAR_3786|M.marinum_M               LAAAHKRIAQLEAELALTRDACDLFNEEAVVPPKRRRAITEGLIARGHSA
Mb2838c|M.bovis_AF2122/97           ---------------DGELKEHISRVHAANYGVYGARKVWLTLNREGIEV
Rv3475|M.tuberculosis_H37Rv         ---------------DGELKEHISRVHAANYGVYGARKVWLTLNREGIEV
MAV_5037|M.avium_104                ---------------DAVLGPALCQLWKDNYCVYGARKLWKTARREGHDV
                                                                          :       *   

TH_4372|M.thermoresistible__bu      S----------------------ENTVAKIMAEMGIEGISPRTFKVKTTQ
Mvan_5060|M.vanbaalenii_PYR-1       S----------------------VNTVAAIMAEMGIEGISPRTFKVKTTV
Mflv_4642|M.gilvum_PYR-GCK          G----------------------PELVRTLMRELNLVALQPKPYKR-TTI
MAB_2088|M.abscessus_ATCC_1997      A----------------------ERTAWRICSQQQLWSVFGKKRGKNGKP
MSMEG_1249|M.smegmatis_MC2_155      G----------------------ENRVARLCSQERIWSIFAKKRGLNRRS
MMAR_3786|M.marinum_M               RSACRVTGLARSLLQYHRRRLVPDREVRRLIVADTITEIYQRSRGTYGRK
Mb2838c|M.bovis_AF2122/97           A----------------------RCTVERLMTKLGLSGTTRGKARRTTIA
Rv3475|M.tuberculosis_H37Rv         A----------------------RCTVERLMTKLGLSGTTRGKARRTTIA
MAV_5037|M.avium_104                G----------------------RDQVARLMRAAGIEGVRRGKRVRTTKA
                                                              .  :     :              

TH_4372|M.thermoresistible__bu      VD---------------------------------------PTASFPPDR
Mvan_5060|M.vanbaalenii_PYR-1       VD---------------------------------------PAASFPPDR
Mflv_4642|M.gilvum_PYR-GCK          AG---------------------------------------ESATAVPDL
MAB_2088|M.abscessus_ATCC_1997      ------------------------------------------GPPVHDDL
MSMEG_1249|M.smegmatis_MC2_155      ------------------------------------------GPPVHDDL
MMAR_3786|M.marinum_M               RVRAALLADYDMNVNHKLVNSIMSEHGLYGLPRHGRRKPNLIGVHTPVDL
Mb2838c|M.bovis_AF2122/97           DP----------------------------------------ATARPADL
Rv3475|M.tuberculosis_H37Rv         DP----------------------------------------ATARPADL
MAV_5037|M.avium_104                DP----------------------------------------AAARHPDL
                                                                                    * 

TH_4372|M.thermoresistible__bu      VGRAFDQGRLDAVWTSDITYLTCGEGDAYLCAIRDEHSRRVLGWSLADHM
Mvan_5060|M.vanbaalenii_PYR-1       VGRIFDQGRLDAVWTSDITYLTCGEGDAYLCAIRDEHSRRVLGWSVADHM
Mflv_4642|M.gilvum_PYR-GCK          VARDFTADRPGVKLVGDITYIRTWAGWLYLATVIDCFNKEVIGYAMADHM
MAB_2088|M.abscessus_ATCC_1997      VQRDFTAETPNMLWLSDITEHYTGDGKLYLCAIKDAFSNRIVGYSIDSRM
MSMEG_1249|M.smegmatis_MC2_155      VQRQFSTHAPNQVWLADITEHRTDEGKLYLCALKDVYSNRIVGYSIDSRM
MMAR_3786|M.marinum_M               INRRFTATKPNELWCTDITEHPARDGKVYCCAILDCFSRMIVARTFSTTA
Mb2838c|M.bovis_AF2122/97           VQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTM
Rv3475|M.tuberculosis_H37Rv         VQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTM
MAV_5037|M.avium_104                VHRNFAAAAPNQLWVTDLTFVPTWAGVAYVCFIIDAHSRMIVGWRVASHM
                                    : * *     .     *:*      *  * . : * . . ::.  .    

TH_4372|M.thermoresistible__bu      RTELVEAAVDAAVFTRAGH----VAGTVMHSDRGSQFTSYDMAQACTRHG
Mvan_5060|M.vanbaalenii_PYR-1       RTELVEQAVDAAVFTRGGS----VAGTILHSDRGSQYTSHDLAKACSDHG
Mflv_4642|M.gilvum_PYR-GCK          RTELATGALEMAARN-HAL----EPGCIMHTDRGTQYTSTDYAIKIADLD
MAB_2088|M.abscessus_ATCC_1997      KSRLATAALRNAVGR-RGV----VAGCVVHTDRGSQFRSRKFVQALHHHG
MSMEG_1249|M.smegmatis_MC2_155      KSSLAVAALEHAVAL-RSP----VA-TIVHSDRGSQFRSRKFVHALSHNG
MMAR_3786|M.marinum_M               DTALVNNAVNMAVDH-RNR----SGPTILHADHGTQFTSWSFGENMRRWG
Mb2838c|M.bovis_AF2122/97           ATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEAG
Rv3475|M.tuberculosis_H37Rv         ATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEAG
MAV_5037|M.avium_104                RTSMVLDALEMARWSRG----TTLQDLICHSDAGSQFTSIRYGERLAEIG
                                     : :.  *:  *               : *:* *:*: *          .

TH_4372|M.thermoresistible__bu      LLRSMGATGICWDNAGSESLWSTVKHEYYK----RHAFTTYANLTAGLDN
Mvan_5060|M.vanbaalenii_PYR-1       LRRSMGATGICWDNAGSESLWSTVKHEYYK----RHAFTTYANLTAGLDN
Mflv_4642|M.gilvum_PYR-GCK          MRASLGRTGICWDNALAESFFAALKNERVH----HMVYPTRKKARADIAR
MAB_2088|M.abscessus_ATCC_1997      MVGSMGRVGAAGDNAAMESFFSLLQKNVLD----RRRWATREELRIAIVT
MSMEG_1249|M.smegmatis_MC2_155      LHGSMGRVGACGDNAAMESFFALLQRNVLD----RRRWTTRAELRLAIVT
MMAR_3786|M.marinum_M               LLGSFGTVGDCFDNAAMESFWARLQVELLN----TRKWATTIELAAAMAD
Mb2838c|M.bovis_AF2122/97           IQPSVGAVGSSYDNALAETINGLYKTELIK-PGK--PWRSIEDVELATAR
Rv3475|M.tuberculosis_H37Rv         IQPSVGAVGSSYDNALAETINGLYKTELIK-PGK--PWRSIEDVELATAR
MAV_5037|M.avium_104                AVPSIGTVGDSFDNALAETVNGYYKAELIYGPARTGPWKTVEDVELATLS
                                       *.* .* . ***  *:. .  : :          : :  .       

TH_4372|M.thermoresistible__bu      YIR-FYNHERRHSSLGMISPIDFDLSLDILLSTQV------
Mvan_5060|M.vanbaalenii_PYR-1       YLH-YYNHDRRHSSLGMISPIDFEIAARINQQSS-------
Mflv_4642|M.gilvum_PYR-GCK          YIELFYNRRRLHSALGYRTPHEVRIEYMNSQLAA-------
MAB_2088|M.abscessus_ATCC_1997      WIERTYHRRRRQGALGRLTPVEYEAIMTTTASQAA------
MSMEG_1249|M.smegmatis_MC2_155      WIERTYHRRRRQRALGRLTPIEFELLHTPVATAA-------
MMAR_3786|M.marinum_M               YIDNFYNIERRHSYLGNISPTEFETLWTSTYSIPQLA----
Mb2838c|M.bovis_AF2122/97           WVD-WFNHRRLYQYCGDVPPVELEAAYYAQR--QRPAAG--
Rv3475|M.tuberculosis_H37Rv         WVD-WFNHRRLYQYCGDVPPVELEAAYYAQR--QRPAAG--
MAV_5037|M.avium_104                WVY-WHNTSRLHSYLGDIPPAEFEAAFYDAYRTDQPLIGIQ
                                    ::   .:  *     *  .* :