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M. thermoresistible (build 8) TH_3162 (-)

annotation: Integrase, catalytic region
coordinates: 3626022 - 3626738
length: 239

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3162--100% (239)Integrase, catalytic region
M. thermoresistible (build 8)TH_4372-7e-5951.10% (227) PUTATIVE Integrase, catalytic region
M. thermoresistible (build 8)TH_3317-1e-2432.44% (225) PUTATIVE Integrase, catalytic region

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2838c-5e-2933.92% (227) transposase
M. gilvum PYR-GCKMflv_4642-4e-3739.21% (227) integrase catalytic subunit
M. tuberculosis H37RvRv3475-5e-2933.92% (227) transposase IS6110
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2088-2e-3236.28% (215) transposase
M. marinum MMMAR_3786-8e-3035.43% (223) transposase
M. avium 104MAV_3271-2e-2432.20% (205) transposase
M. smegmatis MC2 155MSMEG_6888-6e-3436.79% (212) transposase subunit
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_5060-6e-5951.10% (227) integrase catalytic subunit

CLUSTAL 2.0.9 multiple sequence alignment


TH_3162|M.thermoresistible__bu      --------------------------------------------------
Mvan_5060|M.vanbaalenii_PYR-1       --------------------------------------MSRFELIAAECA
Mflv_4642|M.gilvum_PYR-GCK          -------------------------------------MSQKYAFIAAEHA
MAB_2088|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_6888|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3786|M.marinum_M               ---------------------------------------MPRQYSSSVRR
Mb2838c|M.bovis_AF2122/97           --------------------------------------------------
Rv3475|M.tuberculosis_H37Rv         AEALAAGQRRIAKGERDFKDRVGFLRGRARPASTLITRFIADHQGHREGP
MAV_3271|M.avium_104                --------------------------------------------------
                                                                                      

TH_3162|M.thermoresistible__bu      --------------------------------------------------
Mvan_5060|M.vanbaalenii_PYR-1       D--------HDIATLTELLGVSRSGYYAWEARQRRTEPTARQQWRRD---
Mflv_4642|M.gilvum_PYR-GCK          DGATFAGMAPTIVQMLKWLGVSKSGFYEWWGRP----ASAAMCRREE---
MAB_2088|M.abscessus_ATCC_1997      -------------MTRRVLKLARQPYYRWRANPITDAELVEAYR------
MSMEG_6888|M.smegmatis_MC2_155      -------------MTCRVLKLARQPYYRWRANPITDAEIIEAYR------
MMAR_3786|M.marinum_M               QIVSRLRVGEPVAVVAAETGVCQATLFRWKRQALIDAGVIEGTPSVEADE
Mb2838c|M.bovis_AF2122/97           ------------------MPIAPSTYYDHINREPSRRELRDGELK-----
Rv3475|M.tuberculosis_H37Rv         DGLRWGVESICTQLTELGVPIAPSTYYDHINREPSRRELRDGELK-----
MAV_3271|M.avium_104                --------------------MALSTYYDAKARVPSARALRDAVLG-----
                                                                                      

TH_3162|M.thermoresistible__bu      ------------------LDAKVAAFHKASDGVYGAPRILADLREDG---
Mvan_5060|M.vanbaalenii_PYR-1       ------------------LEVKILAHWKESKRTYGSPRITADLHAAG---
Mflv_4642|M.gilvum_PYR-GCK          ------------------LKLKIAALFTSFGAVYGYRRIHAELVRAG---
MAB_2088|M.abscessus_ATCC_1997      --------------------ANALFDAHGEDPEFGYRYLVEEAREAG---
MSMEG_6888|M.smegmatis_MC2_155      --------------------ANALFDAHRDDPEFGYRYLVEEARDAG---
MMAR_3786|M.marinum_M               LAAAHKRIAQLEAELALTRDACDLFNEEAVVPPKRRRAITEGLIARGHSA
Mb2838c|M.bovis_AF2122/97           --------------------EHISRVHAANYGVYGARKVWLTLNREG---
Rv3475|M.tuberculosis_H37Rv         --------------------EHISRVHAANYGVYGARKVWLTLNREG---
MAV_3271|M.avium_104                --------------------PALCQLWKDNYCVYGARKLWKTARRDG---
                                                                          :       *   

TH_3162|M.thermoresistible__bu      -------------------EKVSRKTVAASLRRQGLAGISPRTFAPVTT-
Mvan_5060|M.vanbaalenii_PYR-1       -------------------VSVSVNTVAAIMAEMGIEGISPRTFKVKTT-
Mflv_4642|M.gilvum_PYR-GCK          -------------------ERVGPELVRTLMRELNLVALQPKPYKRTTI-
MAB_2088|M.abscessus_ATCC_1997      -------------------EPMAERTAWRICSQQQLWSVFGKKRGKNGK-
MSMEG_6888|M.smegmatis_MC2_155      -------------------ETMAERTAWRICSQNRLWSVFGKKRGKNGK-
MMAR_3786|M.marinum_M               RSACRVTGLARSLLQYHRRRLVPDREVRRLIVADTITEIYQRSRGTYGRK
Mb2838c|M.bovis_AF2122/97           -------------------IEVARCTVERLMTKLGLSGTTRGKARRTTI-
Rv3475|M.tuberculosis_H37Rv         -------------------IEVARCTVERLMTKLGLSGTTRGKARRTTI-
MAV_3271|M.avium_104                -------------------HDVGRDQVARLMRAAGIEGVRRGKRVRTTK-
                                                         :    .        :              

TH_3162|M.thermoresistible__bu      --------------------------------------IVDLDTPVPKDL
Mvan_5060|M.vanbaalenii_PYR-1       --------------------------------------VVDPAASFPPDR
Mflv_4642|M.gilvum_PYR-GCK          --------------------------------------AGESATAVP-DL
MAB_2088|M.abscessus_ATCC_1997      -----------------------------------------PGPPVHDDL
MSMEG_6888|M.smegmatis_MC2_155      -----------------------------------------VGPPVHDDL
MMAR_3786|M.marinum_M               RVRAALLADYDMNVNHKLVNSIMSEHGLYGLPRHGRRKPNLIGVHTPVDL
Mb2838c|M.bovis_AF2122/97           ---------------------------------------ADPATARPADL
Rv3475|M.tuberculosis_H37Rv         ---------------------------------------ADPATARPADL
MAV_3271|M.avium_104                ---------------------------------------ADPAAARHPDL
                                                                                    * 

TH_3162|M.thermoresistible__bu      VNRRFDVGELDRVWTSDITYLRTGEGWLYLCAVRDGCSRRVIGWAIDDHM
Mvan_5060|M.vanbaalenii_PYR-1       VGRIFDQGRLDAVWTSDITYLTCGEGDAYLCAIRDEHSRRVLGWSVADHM
Mflv_4642|M.gilvum_PYR-GCK          VARDFTADRPGVKLVGDITYIRTWAGWLYLATVIDCFNKEVIGYAMADHM
MAB_2088|M.abscessus_ATCC_1997      VQRDFTAETPNMLWLSDITEHYTGDGKLYLCAIKDAFSNRIVGYSIDSRM
MSMEG_6888|M.smegmatis_MC2_155      VERDFTAGGPNQLWLSDITEHRTDEGKLYLCAIKDVFSNRIVGYSIDARM
MMAR_3786|M.marinum_M               INRRFTATKPNELWCTDITEHPARDGKVYCCAILDCFSRMIVARTFSTTA
Mb2838c|M.bovis_AF2122/97           VQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTM
Rv3475|M.tuberculosis_H37Rv         VQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTM
MAV_3271|M.avium_104                VHRNFAAAAPNQLWVTDLTFVPTWAGVAYVCFIIDAHSRMIVGWRVASHM
                                    : * *     .     *:*      *  * . : *   . ::.  .    

TH_3162|M.thermoresistible__bu      HTDLVESAVAMAVAMRGQL----AEQVVLHADRGCQFTSAQLARFSRGHN
Mvan_5060|M.vanbaalenii_PYR-1       RTELVEQAVDAAVFTRGGS----VAGTILHSDRGSQYTSHDLAKACSDHG
Mflv_4642|M.gilvum_PYR-GCK          RTELATGALEMAARN-HAL----EPGCIMHTDRGTQYTSTDYAIKIADLD
MAB_2088|M.abscessus_ATCC_1997      KSRLATAALRNAVGRRGVV----AG-CVVHTDRGSQFRSRKFVQALHHHG
MSMEG_6888|M.smegmatis_MC2_155      KSRLATTALSSAVARRGDV----AG-CILHSDRGSQFRSRRFVRVLGRHE
MMAR_3786|M.marinum_M               DTALVNNAVNMAVDHRNRS----GP-TILHADHGTQFTSWSFGENMRRWG
Mb2838c|M.bovis_AF2122/97           ATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEAG
Rv3475|M.tuberculosis_H37Rv         ATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEAG
MAV_3271|M.avium_104                RTSMVLDALEMARWSRG----TTLQDLICHSDAGSQFTSIRYGERLAEIG
                                     : :.  *:  *               : *:* * *: *           

TH_3162|M.thermoresistible__bu      LARSVGRTGVCWDNAQHESFWGTMKVEFYD----RHLWPTKAAAKLAVGD
Mvan_5060|M.vanbaalenii_PYR-1       LRRSMGATGICWDNAGSESLWSTVKHEYYK----RHAFTTYANLTAGLDN
Mflv_4642|M.gilvum_PYR-GCK          MRASLGRTGICWDNALAESFFAALKNERVH----HMVYPTRKKARADIAR
MAB_2088|M.abscessus_ATCC_1997      MVGSMGRVGAAGDNAAMESFFSLLQKNVLD----RRRWATREELRIAIVT
MSMEG_6888|M.smegmatis_MC2_155      MVGSMGRVGAAGDNAAMESFFALLQKNVLD----RRRWRTREELRIAIVT
MMAR_3786|M.marinum_M               LLGSFGTVGDCFDNAAMESFWARLQVELLN----TRKWATTIELAAAMAD
Mb2838c|M.bovis_AF2122/97           IQPSVGAVGSSYDNALAETINGLYKTELIK-PGK--PWRSIEDVELATAR
Rv3475|M.tuberculosis_H37Rv         IQPSVGAVGSSYDNALAETINGLYKTELIK-PGK--PWRSIEDVELATAR
MAV_3271|M.avium_104                AVPSIGTVGDSFDNALAETVNGYYKAELIYGPARSRPWKTVEDVELATLS
                                       *.* .* . ***  *:. .  : :          : :          

TH_3162|M.thermoresistible__bu      WIERVYNRRRRPSAT---------PAAAATQRSA-------
Mvan_5060|M.vanbaalenii_PYR-1       YLH-YYNHDRRHSSLGMISPIDFEIAARINQQSS-------
Mflv_4642|M.gilvum_PYR-GCK          YIELFYNRRRLHSALGYRTPHEVRIEYMNSQLAA-------
MAB_2088|M.abscessus_ATCC_1997      WIERTYHRRRRQGALGRLTPVEYEAIMTTTASQAA------
MSMEG_6888|M.smegmatis_MC2_155      WIERTYHRRRRQAGLGRLTPIEFEAIMTTPASQAA------
MMAR_3786|M.marinum_M               YIDNFYNIERRHSYLGNISPTEFETLWTSTYSIPQLA----
Mb2838c|M.bovis_AF2122/97           WVD-WFNHRRLYQYCGDVPPVELEAAYYAQR--QRPAAG--
Rv3475|M.tuberculosis_H37Rv         WVD-WFNHRRLYQYCGDVPPVELEAAYYAQR--QRPAAG--
MAV_3271|M.avium_104                WVH-WHNTSRLHSYLGDIPPTEFEAAFYDAYRTDQPLIGIQ
                                    ::.  .:  *