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SQKYAFIAAEHADGATFAGMAPTIVQMLKWLGVSKSGFYEWWGRPASAAMCRREELKLKIAALFTSFGAV YGYRRIHAELVRAGERVGPELVRTLMRELNLVALQPKPYKRTTIAGESATAVPDLVARDFTADRPGVKLV GDITYIRTWAGWLYLATVIDCFNKEVIGYAMADHMRTELATGALEMAARNHALEPGCIMHTDRGTQYTST DYAIKIADLDMRASLGRTGICWDNALAESFFAALKNERVHHMVYPTRKKARADIARYIELFYNRRRLHSA LGYRTPHEVRIEYMNSQLAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4642 | - | - | 100% (301) | integrase catalytic subunit |
| M. gilvum PYR-GCK | Mflv_4633 | - | e-176 | 100.00% (301) | integrase catalytic subunit |
| M. gilvum PYR-GCK | Mflv_4620 | - | e-176 | 100.00% (301) | integrase catalytic subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2838c | - | 2e-30 | 31.84% (267) | transposase |
| M. tuberculosis H37Rv | Rv3475 | - | 1e-30 | 32.26% (279) | transposase IS6110 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2088 | - | 4e-32 | 34.48% (261) | transposase |
| M. marinum M | MMAR_2548 | - | 1e-27 | 32.97% (279) | transposase, ISMyma03_aa2 |
| M. avium 104 | MAV_1454 | - | 3e-32 | 32.97% (273) | transposase |
| M. smegmatis MC2 155 | MSMEG_6888 | - | 2e-29 | 33.08% (260) | transposase subunit |
| M. thermoresistible (build 8) | TH_4372 | - | 2e-40 | 35.69% (269) | PUTATIVE Integrase, catalytic region |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_5060 | - | 6e-42 | 35.59% (295) | integrase catalytic subunit |
CLUSTAL 2.0.9 multiple sequence alignment
TH_4372|M.thermoresistible__bu --------------------------------------VSRFELIAAECA
Mvan_5060|M.vanbaalenii_PYR-1 --------------------------------------MSRFELIAAECA
Mflv_4642|M.gilvum_PYR-GCK -------------------------------------MSQKYAFIAAEHA
MAB_2088|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6888|M.smegmatis_MC2_155 --------------------------------------------------
Mb2838c|M.bovis_AF2122/97 --------------------------------------------------
Rv3475|M.tuberculosis_H37Rv AEALAAGQRRIAKGERDFKDRVGFLRGRARPASTLITRFIADHQGHREGP
MAV_1454|M.avium_104 --------------------------------------------------
MMAR_2548|M.marinum_M --------------------------------------------------
TH_4372|M.thermoresistible__bu H--------HDVSKLAELLGVSRSGYYAWAARQRRVELSPRQQWRRDLEV
Mvan_5060|M.vanbaalenii_PYR-1 D--------HDIATLTELLGVSRSGYYAWEARQRRTEPTARQQWRRDLEV
Mflv_4642|M.gilvum_PYR-GCK DGATFAGMAPTIVQMLKWLGVSKSGFYEWWGRPASAAMCRRE----ELKL
MAB_2088|M.abscessus_ATCC_1997 -------------MTRRVLKLARQPYYRWRANPITDAELVEA-----YRA
MSMEG_6888|M.smegmatis_MC2_155 -------------MTCRVLKLARQPYYRWRANPITDAEIIEA-----YRA
Mb2838c|M.bovis_AF2122/97 ------------------MPIAPSTYYDHINREPSRRELRDG----ELKE
Rv3475|M.tuberculosis_H37Rv DGLRWGVESICTQLTELGVPIAPSTYYDHINREPSRRELRDG----ELKE
MAV_1454|M.avium_104 --------------------MALSTYYDTKARVPSARALRDA----VLGP
MMAR_2548|M.marinum_M ------------MLTEHGIKISPSTYYEWMKRTPSKQQLRDE----AVTA
:: . :* .
TH_4372|M.thermoresistible__bu KILAHWQAS--GRTYGSPRITADLHAEGVGVSENTVAKIMAEMGIEGISP
Mvan_5060|M.vanbaalenii_PYR-1 KILAHWKES--KRTYGSPRITADLHAAGVSVSVNTVAAIMAEMGIEGISP
Mflv_4642|M.gilvum_PYR-GCK KIAALFTSF--GAVYGYRRIHAELVRAGERVGPELVRTLMRELNLVALQP
MAB_2088|M.abscessus_ATCC_1997 NALFDAHGE--DPEFGYRYLVEEAREAGEPMAERTAWRICSQQQLWSVFG
MSMEG_6888|M.smegmatis_MC2_155 NALFDAHRD--DPEFGYRYLVEEARDAGETMAERTAWRICSQNRLWSVFG
Mb2838c|M.bovis_AF2122/97 HISRVHAAN--YGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTR
Rv3475|M.tuberculosis_H37Rv HISRVHAAN--YGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTR
MAV_1454|M.avium_104 ALCQLWKDN--YCVYGARKLWKTARREGHDVGRDQVARLMRAAGIEGVRR
MMAR_2548|M.marinum_M SIKEFRERNPLNKTLGSRKVWIKLRGDGMDVARCTVERLMQANRWQGARY
* : * :. . : .
TH_4372|M.thermoresistible__bu RTFKVKTTQVDPTASFPPDRVGRAFDQGRLDAVWTSDITYLTCGEGDAYL
Mvan_5060|M.vanbaalenii_PYR-1 RTFKVKTTVVDPAASFPPDRVGRIFDQGRLDAVWTSDITYLTCGEGDAYL
Mflv_4642|M.gilvum_PYR-GCK KPYKR-TTIAGESATAVPDLVARDFTADRPGVKLVGDITYIRTWAGWLYL
MAB_2088|M.abscessus_ATCC_1997 ---KKRGKNGKPGPPVHDDLVQRDFTAETPNMLWLSDITEHYTGDGKLYL
MSMEG_6888|M.smegmatis_MC2_155 ---KKRGKNGKVGPPVHDDLVERDFTAGGPNQLWLSDITEHRTDEGKLYL
Mb2838c|M.bovis_AF2122/97 GK-ARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYV
Rv3475|M.tuberculosis_H37Rv GK-ARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYV
MAV_1454|M.avium_104 GK-RVRTTKPDPAAARHPDLVKRNFTATAPNQLWVTDLTFVPTWAGVAYV
MMAR_2548|M.marinum_M GG-APKTTIQDEKAQRATDLVDRVFAAPAPNRLWVADFTYCPTWAGMVYV
. . * * * * . *:* * *:
TH_4372|M.thermoresistible__bu CAIRDEHSRRVLGWSLADHMRTELVEAAVDAAVFTRAGH----VAGTVMH
Mvan_5060|M.vanbaalenii_PYR-1 CAIRDEHSRRVLGWSVADHMRTELVEQAVDAAVFTRGGS----VAGTILH
Mflv_4642|M.gilvum_PYR-GCK ATVIDCFNKEVIGYAMADHMRTELATGALEMAARN-HAL----EPGCIMH
MAB_2088|M.abscessus_ATCC_1997 CAIKDAFSNRIVGYSIDSRMKSRLATAALRNAVGR-RGV----VAGCVVH
MSMEG_6888|M.smegmatis_MC2_155 CAIKDVFSNRIVGYSIDARMKSRLATTALSSAVAR-RGD----VAGCILH
Mb2838c|M.bovis_AF2122/97 AFVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHH
Rv3475|M.tuberculosis_H37Rv AFVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHH
MAV_1454|M.avium_104 CFIIDAYSRMIVGWRVASHMRTSMVLDALEMARWSRGN----MLPGLRCH
MMAR_2548|M.marinum_M AFVIDAFARRVIGWRAATSMKTALVIDALEHAFFTRAQEGFTDLSGLVAH
. : * . . ::*: * : :. *: * . *
TH_4372|M.thermoresistible__bu SDRGSQFTSYDMAQACTRHGLLRSMGATGICWDNAGSESLWSTVKHEYYK
Mvan_5060|M.vanbaalenii_PYR-1 SDRGSQYTSHDLAKACSDHGLRRSMGATGICWDNAGSESLWSTVKHEYYK
Mflv_4642|M.gilvum_PYR-GCK TDRGTQYTSTDYAIKIADLDMRASLGRTGICWDNALAESFFAALKNERVH
MAB_2088|M.abscessus_ATCC_1997 TDRGSQFRSRKFVQALHHHGMVGSMGRVGAAGDNAAMESFFSLLQKNVLD
MSMEG_6888|M.smegmatis_MC2_155 SDRGSQFRSRRFVRVLGRHEMVGSMGRVGAAGDNAAMESFFALLQKNVLD
Mb2838c|M.bovis_AF2122/97 TDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIK
Rv3475|M.tuberculosis_H37Rv TDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIK
MAV_1454|M.avium_104 SDAGSQFTSIRYGERLAEIGAVPSIGTVGDSFDNALAETVNGYYKAELIY
MMAR_2548|M.marinum_M SDAGSQYTSIAFTTRLIDAGIDASVGSVADAYDNALAETTVGSFKNELIR
:* *:*: * *:* .. . *** *: . : :
TH_4372|M.thermoresistible__bu ----RHAFTTYANLTAGLDNYIR-FYNHERRHSSLGMISPIDFDLSLDIL
Mvan_5060|M.vanbaalenii_PYR-1 ----RHAFTTYANLTAGLDNYLH-YYNHDRRHSSLGMISPIDFEIAARIN
Mflv_4642|M.gilvum_PYR-GCK ----HMVYPTRKKARADIARYIELFYNRRRLHSALGYRTPHEVRIEYMNS
MAB_2088|M.abscessus_ATCC_1997 ----RRRWATREELRIAIVTWIERTYHRRRRQGALGRLTPVEYEAIMTTT
MSMEG_6888|M.smegmatis_MC2_155 ----RRRWRTREELRIAIVTWIERTYHRRRRQAGLGRLTPIEFEAIMTTP
Mb2838c|M.bovis_AF2122/97 -PGK--PWRSIEDVELATARWVD-WFNHRRLYQYCGDVPPVELEAAYYAQ
Rv3475|M.tuberculosis_H37Rv -PGK--PWRSIEDVELATARWVD-WFNHRRLYQYCGDVPPVELEAAYYAQ
MAV_1454|M.avium_104 GPARTGPWKTVEDVELATLSWVY-WHNTSRLHSYLGDIPPAEFEAAFYDA
MMAR_2548|M.marinum_M ---RQGPWRDVDHVEIGTLNWVD-WFNNERPHEYLADLTPTQAEALHYRH
: . :: .: * . .* :
TH_4372|M.thermoresistible__bu LSTQV------
Mvan_5060|M.vanbaalenii_PYR-1 QQSS-------
Mflv_4642|M.gilvum_PYR-GCK QLAA-------
MAB_2088|M.abscessus_ATCC_1997 ASQAA------
MSMEG_6888|M.smegmatis_MC2_155 ASQAA------
Mb2838c|M.bovis_AF2122/97 R--QRPAAG--
Rv3475|M.tuberculosis_H37Rv R--QRPAAG--
MAV_1454|M.avium_104 YRTDQPLIGIQ
MMAR_2548|M.marinum_M KS-SLAAAG--