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MPRQYSSSVRRQIVSRLRVGEPVAVVAAETGVCQATLFRWKRQALIDAGVIEGTPSVEADELAAAHKRIA QLEAELALTRDACDLFNEEAVVPPKRRRAITEGLIARGHSARSACRVTGLARSLLQYHRRRLVPDREVRR LIVADTITEIYQRSRGTYGRKRVRAALLADYDMNVNHKLVNSIMSEHGLYGLPRHGRRKPNLIGVHTPVD LINRRFTATKPNELWCTDITEHPARDGKVYCCAILDCFSRMIVARTFSTTADTALVNNAVNMAVDHRNRS GPTILHADHGTQFTSWSFGENMRRWGLLGSFGTVGDCFDNAAMESFWARLQVELLNTRKWATTIELAAAM ADYIDNFYNIERRHSYLGNISPTEFETLWTSTYSIPQLA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3786 | - | - | 100% (389) | transposase |
| M. marinum M | MMAR_2548 | - | 5e-23 | 29.34% (259) | transposase, ISMyma03_aa2 |
| M. marinum M | MMAR_2532 | - | 5e-23 | 29.34% (259) | transposase, ISMyma03_aa2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2838c | - | 1e-26 | 29.10% (268) | transposase |
| M. gilvum PYR-GCK | Mflv_3195 | - | 2e-35 | 39.60% (202) | integrase catalytic subunit |
| M. tuberculosis H37Rv | Rv3475 | - | 1e-26 | 29.10% (268) | transposase IS6110 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2088 | - | 2e-36 | 40.10% (202) | transposase |
| M. avium 104 | MAV_1454 | - | 3e-33 | 34.93% (272) | transposase |
| M. smegmatis MC2 155 | MSMEG_6888 | - | 2e-37 | 35.56% (270) | transposase subunit |
| M. thermoresistible (build 8) | TH_4372 | - | 8e-33 | 33.94% (277) | PUTATIVE Integrase, catalytic region |
| M. ulcerans Agy99 | MUL_2306 | - | 5e-05 | 31.58% (76) | transposase |
| M. vanbaalenii PYR-1 | Mvan_5959 | - | 1e-36 | 40.10% (202) | integrase catalytic subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3195|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5959|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6888|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2088|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_2306|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3786|M.marinum_M MPRQYSSSVRRQIVSRLRVGEPVAVVAAETGVCQATLFRWKRQALIDAGV
Mb2838c|M.bovis_AF2122/97 --------------------------------------------------
Rv3475|M.tuberculosis_H37Rv -------------------------------------------------A
MAV_1454|M.avium_104 --------------------------------------------------
TH_4372|M.thermoresistible__bu --------------------------------------------------
Mflv_3195|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5959|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6888|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2088|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_2306|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3786|M.marinum_M IEGTPSVEADELAAAHKRIAQLEAELALTRDACDLFNEEAVVPPKRRRAI
Mb2838c|M.bovis_AF2122/97 --------------------------------------------------
Rv3475|M.tuberculosis_H37Rv EALAAGQRRIAKGERDFKDRVGFLRGRARPASTLITRFIADHQGHREGPD
MAV_1454|M.avium_104 --------------------------------------------------
TH_4372|M.thermoresistible__bu ---------------------------------------------VSRFE
Mflv_3195|M.gilvum_PYR-GCK MKELAADGIPVAVTCRVLKLSRQPYYRWLAD----PITEAELIEAYRANA
Mvan_5959|M.vanbaalenii_PYR-1 MKELAADGIPVAVTCRVLKLSRQPYYRWLAD----PVTDAELVEAYRTNA
MSMEG_6888|M.smegmatis_MC2_155 ------------MTCRVLKLARQPYYRWRAN----PITDAEIIEAYRANA
MAB_2088|M.abscessus_ATCC_1997 ------------MTRRVLKLARQPYYRWRAN----PITDAELVEAYRANA
MUL_2306|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3786|M.marinum_M TEGLIARGHSARSACRVTGLARSLLQYHRRR----LVPDREVRRLIVADT
Mb2838c|M.bovis_AF2122/97 -----------------MPIAPSTYYDHINR----EPSRRELRDGELKEH
Rv3475|M.tuberculosis_H37Rv GLRWGVESICTQLTELGVPIAPSTYYDHINR----EPSRRELRDGELKEH
MAV_1454|M.avium_104 -------------------MALSTYYDTKAR----VPSARALRDAVLGPA
TH_4372|M.thermoresistible__bu LIAAECAHHDVSKLAELLGVSRSGYYAWAARQRRVELSPRQQWRRDLEVK
Mflv_3195|M.gilvum_PYR-GCK LFDAHADDPEFG-YRYLVEEARDAGEPMAERTAWR--ICSQNRLWSVF-G
Mvan_5959|M.vanbaalenii_PYR-1 LVNAHADDPEFG-YRYLVEEAREAGEPMAERTAWR--ICSQNRLWSVF-G
MSMEG_6888|M.smegmatis_MC2_155 LFDAHRDDPEFG-YRYLVEEARDAGETMAERTAWR--ICSQNRLWSVF-G
MAB_2088|M.abscessus_ATCC_1997 LFDAHGEDPEFG-YRYLVEEAREAGEPMAERTAWR--ICSQQQLWSVF-G
MUL_2306|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3786|M.marinum_M ITEIYQRSRGTY-GRKRVRAALLADYDMNVNHKLVNSIMSEHGLYGLP-R
Mb2838c|M.bovis_AF2122/97 ISRVHAANYGVYGARKVWLTLNREGIEVARCTVER--LMTKLGLSGTT-R
Rv3475|M.tuberculosis_H37Rv ISRVHAANYGVYGARKVWLTLNREGIEVARCTVER--LMTKLGLSGTT-R
MAV_1454|M.avium_104 LCQLWKDNYCVYGARKLWKTARREGHDVGRDQVAR--LMRAAGIEGVR-R
TH_4372|M.thermoresistible__bu ILAHWQASGRTYGSPRITADLHAEGVGVSENTVAK--IMAEMGIEGISPR
Mflv_3195|M.gilvum_PYR-GCK KKRGKNGKVGPPVH--DDLVERDFTAEGPNQLWLSDITEHRTGEGKLYLC
Mvan_5959|M.vanbaalenii_PYR-1 KKRGKSGKVGPPVH--DDLVQRDFTADAPNQLWLSDITEHRTDEGKLYLC
MSMEG_6888|M.smegmatis_MC2_155 KKRGKNGKVGPPVH--DDLVERDFTAGGPNQLWLSDITEHRTDEGKLYLC
MAB_2088|M.abscessus_ATCC_1997 KKRGKNGKPGPPVH--DDLVQRDFTAETPNMLWLSDITEHYTGDGKLYLC
MUL_2306|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3786|M.marinum_M HGRRKPNLIGVHTP--VDLINRRFTATKPNELWCTDITEHPARDGKVYCC
Mb2838c|M.bovis_AF2122/97 GKARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVA
Rv3475|M.tuberculosis_H37Rv GKARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVA
MAV_1454|M.avium_104 GKRVRTTKPDPAAARHPDLVKRNFTATAPNQLWVTDLTFVPTWAGVAYVC
TH_4372|M.thermoresistible__bu TFKVKTTQVDPTASFPPDRVGRAFDQGRLDAVWTSDITYLTCGEGDAYLC
Mflv_3195|M.gilvum_PYR-GCK AIKDVFSNRIVGYSIDSRMKSQLAIRALHSAVARRGD-----VAGCILHS
Mvan_5959|M.vanbaalenii_PYR-1 AIKDVFSNRIVGYSIDSRMKSRLATRALHSAVARRGD-----VAGCIVHT
MSMEG_6888|M.smegmatis_MC2_155 AIKDVFSNRIVGYSIDARMKSRLATTALSSAVARRGD-----VAGCILHS
MAB_2088|M.abscessus_ATCC_1997 AIKDAFSNRIVGYSIDSRMKSRLATAALRNAVGRRGV-----VAGCVVHT
MUL_2306|M.ulcerans_Agy99 ---------MVG--------------------------------------
MMAR_3786|M.marinum_M AILDCFSRMIVARTFSTTADTALVNNAVNMAVDHRNR-----SGPTILHA
Mb2838c|M.bovis_AF2122/97 FVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHHT
Rv3475|M.tuberculosis_H37Rv FVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHHT
MAV_1454|M.avium_104 FIIDAYSRMIVGWRVASHMRTSMVLDALEMARWSRGN----MLPGLRCHS
TH_4372|M.thermoresistible__bu AIRDEHSRRVLGWSLADHMRTELVEAAVDAAVFTRAG----HVAGTVMHS
::.
Mflv_3195|M.gilvum_PYR-GCK DRGSQFRSRKFVHALNHHEMVGSMGRVGAAGDNAAMESFFSLLQKNVLD-
Mvan_5959|M.vanbaalenii_PYR-1 DRGSQFRSRRFVHALGHYEMVGSMGRVGAAGDNAAMESFFSLLQKNVLD-
MSMEG_6888|M.smegmatis_MC2_155 DRGSQFRSRRFVRVLGRHEMVGSMGRVGAAGDNAAMESFFALLQKNVLD-
MAB_2088|M.abscessus_ATCC_1997 DRGSQFRSRKFVQALHHHGMVGSMGRVGAAGDNAAMESFFSLLQKNVLD-
MUL_2306|M.ulcerans_Agy99 -------------------TVGAMGRVQAAGDNAAMASFFSLLRKNVLG-
MMAR_3786|M.marinum_M DHGTQFTSWSFGENMRRWGLLGSFGTVGDCFDNAAMESFWARLQVELLN-
Mb2838c|M.bovis_AF2122/97 DRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIK-
Rv3475|M.tuberculosis_H37Rv DRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIK-
MAV_1454|M.avium_104 DAGSQFTSIRYGERLAEIGAVPSIGTVGDSFDNALAETVNGYYKAELIYG
TH_4372|M.thermoresistible__bu DRGSQFTSYDMAQACTRHGLLRSMGATGICWDNAGSESLWSTVKHEYYK-
:.* . . *** :. . : :
Mflv_3195|M.gilvum_PYR-GCK ---RRRWDTREQLRIAIVTWIERTYHRRRRQSGLGRLTPIEFEAIMTTPA
Mvan_5959|M.vanbaalenii_PYR-1 ---RRRWATREELRIAIVTWIERTYHRRRRQSGLGRLTPIEFEAIMTTPA
MSMEG_6888|M.smegmatis_MC2_155 ---RRRWRTREELRIAIVTWIERTYHRRRRQAGLGRLTPIEFEAIMTTPA
MAB_2088|M.abscessus_ATCC_1997 ---RRRWATREELRIAIVTWIERTYHRRRRQGALGRLTPVEYEAIMTTTA
MUL_2306|M.ulcerans_Agy99 ---RRRWETREHLRIAIATWTETHLRPPPSASRSWPVAPVRFEAIMISRA
MMAR_3786|M.marinum_M ---TRKWATTIELAAAMADYIDNFYNIERRHSYLGNISPTEFETLWTSTY
Mb2838c|M.bovis_AF2122/97 PGK--PWRSIEDVELATARWVD-WFNHRRLYQYCGDVPPVELEAAYYAQR
Rv3475|M.tuberculosis_H37Rv PGK--PWRSIEDVELATARWVD-WFNHRRLYQYCGDVPPVELEAAYYAQR
MAV_1454|M.avium_104 PARTGPWKTVEDVELATLSWVY-WHNTSRLHSYLGDIPPAEFEAAFYDAY
TH_4372|M.thermoresistible__bu ---RHAFTTYANLTAGLDNYIR-FYNHERRHSSLGMISPIDFDLSLDILL
: : .: . : . :.* :
Mflv_3195|M.gilvum_PYR-GCK SQAA------
Mvan_5959|M.vanbaalenii_PYR-1 SQAA------
MSMEG_6888|M.smegmatis_MC2_155 SQAA------
MAB_2088|M.abscessus_ATCC_1997 SQAA------
MUL_2306|M.ulcerans_Agy99 IQAA------
MMAR_3786|M.marinum_M SIPQLA----
Mb2838c|M.bovis_AF2122/97 --QRPAAG--
Rv3475|M.tuberculosis_H37Rv --QRPAAG--
MAV_1454|M.avium_104 RTDQPLIGIQ
TH_4372|M.thermoresistible__bu STQV------