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VSRFELIAAECADHDIATLTELLGVSRSGYYAWEARQRRTEPTARQQWRRDLEVKILAHWKESKRTYGSP RITADLHAAGVSVSVNTVAAIMAEMGIEGISPRTFKVKTTVVDPAASFPPDRVGRIFDQGRLDAVWTSDI TYLTCGEGDAYLCAIRDEHSRRVLGWSVADHMRTELVEQAVDAAVFTRGGSVAGTILHSDRGSQYTSHDL AKACSDHGLRRSMGATGICWDNAGSESLWSTVKHEYYKRHAFTTYANLTAGLDNYLHYYNHDRRHSSLGM ISPIDFEIAARINQQSS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5060 | - | - | 100% (297) | integrase catalytic subunit |
| M. vanbaalenii PYR-1 | Mvan_3740 | - | e-175 | 100.00% (297) | integrase catalytic subunit |
| M. vanbaalenii PYR-1 | Mvan_3720 | - | e-175 | 100.00% (297) | integrase catalytic subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2838c | - | 2e-31 | 30.00% (260) | transposase |
| M. gilvum PYR-GCK | Mflv_0608 | - | 6e-43 | 40.75% (292) | integrase catalytic subunit |
| M. tuberculosis H37Rv | Rv3475 | - | 6e-32 | 30.39% (283) | transposase IS6110 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2088 | - | 6e-26 | 29.21% (267) | transposase |
| M. marinum M | MMAR_3786 | - | 4e-30 | 33.33% (276) | transposase |
| M. avium 104 | MAV_3271 | - | 6e-36 | 34.57% (269) | transposase |
| M. smegmatis MC2 155 | MSMEG_1249 | - | 1e-31 | 31.01% (287) | ISMsm7, transposase orfB |
| M. thermoresistible (build 8) | TH_4372 | - | 1e-149 | 85.62% (292) | PUTATIVE Integrase, catalytic region |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5060|M.vanbaalenii_PYR-1 ----------------------------------------------MSRF
TH_4372|M.thermoresistible__bu ----------------------------------------------VSRF
Mflv_0608|M.gilvum_PYR-GCK ----------------------------------------------MSRF
MAB_2088|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_1249|M.smegmatis_MC2_155 ----------------------------------------------MMYP
MMAR_3786|M.marinum_M ---------------------------------------MPRQYSSSVRR
Mb2838c|M.bovis_AF2122/97 --------------------------------------------------
Rv3475|M.tuberculosis_H37Rv AEALAAGQRRIAKGERDFKDRVGFLRGRARPASTLITRFIADHQGHREGP
MAV_3271|M.avium_104 --------------------------------------------------
Mvan_5060|M.vanbaalenii_PYR-1 ELIAAECADHDIATLTELLGVSRSGYYAWEARQRRTEPT-----------
TH_4372|M.thermoresistible__bu ELIAAECAHHDVSKLAELLGVSRSGYYAWAARQRRVELS-----------
Mflv_0608|M.gilvum_PYR-GCK QFVADHLHAFEVKWLCAVVEVARSSFYAWLAG--ADGRA-----------
MAB_2088|M.abscessus_ATCC_1997 -------------MTRRVLKLARQPYYRWRANPITDA-------------
MSMEG_1249|M.smegmatis_MC2_155 LVLDLAADGVPVTVTCRVLGFSTQAFYRWRKAPVSQR-------------
MMAR_3786|M.marinum_M QIVSRLRVGEPVAVVAAETGVCQATLFRWKRQALIDAGVIEGTPSVEADE
Mb2838c|M.bovis_AF2122/97 ------------------MPIAPSTYYDHINREPSRRELR----------
Rv3475|M.tuberculosis_H37Rv DGLRWGVESICTQLTELGVPIAPSTYYDHINREPSRRELR----------
MAV_3271|M.avium_104 --------------------MALSTYYDAKARVPSARALR----------
.. :
Mvan_5060|M.vanbaalenii_PYR-1 ----------ARQQWRRDLEVKILAHWKESKRTYGSPRITADLHA---AG
TH_4372|M.thermoresistible__bu ----------PRQQWRRDLEVKILAHWQASGRTYGSPRITADLHA---EG
Mflv_0608|M.gilvum_PYR-GCK ----------ARRAADEALAERIRAVHDEDN-TYGAPRITAELNDGAPEG
MAB_2088|M.abscessus_ATCC_1997 -------------ELVEAYRANALFDAHGEDPEFGYRYLVEEAREAGEPM
MSMEG_1249|M.smegmatis_MC2_155 -------------DWDDAHLINAARNIHADDPAFGYRFIADELPAHGITA
MMAR_3786|M.marinum_M LAAAHKRIAQLEAELALTRDACDLFNEEAVVPPKRRRAITEGLIARGHSA
Mb2838c|M.bovis_AF2122/97 ---------------DGELKEHISRVHAANYGVYGARKVWLTLNREGIEV
Rv3475|M.tuberculosis_H37Rv ---------------DGELKEHISRVHAANYGVYGARKVWLTLNREGIEV
MAV_3271|M.avium_104 ---------------DAVLGPALCQLWKDNYCVYGARKLWKTARRDGHDV
:
Mvan_5060|M.vanbaalenii_PYR-1 VSVS-------------------VNTVAAIMAEMGIEGISPRTFKVKTTV
TH_4372|M.thermoresistible__bu VGVS-------------------ENTVAKIMAEMGIEGISPRTFKVKTTQ
Mflv_0608|M.gilvum_PYR-GCK QRVN-------------------HKRVARVMRGAGIAGYR-RRRRVKTTV
MAB_2088|M.abscessus_ATCC_1997 A----------------------ERTAWRICSQQQLWSVFGKKRGKNGKP
MSMEG_1249|M.smegmatis_MC2_155 G----------------------ENRVARLCSQERIWSIFAKKRGLNRRS
MMAR_3786|M.marinum_M RSACRVTGLARSLLQYHRRRLVPDREVRRLIVADTITEIYQRSRGTYGRK
Mb2838c|M.bovis_AF2122/97 A----------------------RCTVERLMTKLGLSGTTRGKARRTTIA
Rv3475|M.tuberculosis_H37Rv A----------------------RCTVERLMTKLGLSGTTRGKARRTTIA
MAV_3271|M.avium_104 G----------------------RDQVARLMRAAGIEGVRRGKRVRTTKA
. : :
Mvan_5060|M.vanbaalenii_PYR-1 VDP---------------------------------------AASFPPDR
TH_4372|M.thermoresistible__bu VDP---------------------------------------TASFPPDR
Mflv_0608|M.gilvum_PYR-GCK ADP---------------------------------------ANQKVPDL
MAB_2088|M.abscessus_ATCC_1997 ------------------------------------------GPPVHDDL
MSMEG_1249|M.smegmatis_MC2_155 ------------------------------------------GPPVHDDL
MMAR_3786|M.marinum_M RVRAALLADYDMNVNHKLVNSIMSEHGLYGLPRHGRRKPNLIGVHTPVDL
Mb2838c|M.bovis_AF2122/97 DP----------------------------------------ATARPADL
Rv3475|M.tuberculosis_H37Rv DP----------------------------------------ATARPADL
MAV_3271|M.avium_104 DP----------------------------------------AAARHPDL
*
Mvan_5060|M.vanbaalenii_PYR-1 VGRIFDQGRLDAVWTSDITYLTCGEGD-AYLCAIRDEHSRRVLGWSVADH
TH_4372|M.thermoresistible__bu VGRAFDQGRLDAVWTSDITYLTCGEGD-AYLCAIRDEHSRRVLGWSLADH
Mflv_0608|M.gilvum_PYR-GCK LKRDFTAAQVNTRYVGDITYLPLATGANLYLATVIDCCSRRVAGWAIADH
MAB_2088|M.abscessus_ATCC_1997 VQRDFTAETPNMLWLSDITEHYTGDGK-LYLCAIKDAFSNRIVGYSIDSR
MSMEG_1249|M.smegmatis_MC2_155 VQRQFSTHAPNQVWLADITEHRTDEGK-LYLCALKDVYSNRIVGYSIDSR
MMAR_3786|M.marinum_M INRRFTATKPNELWCTDITEHPARDGK-VYCCAILDCFSRMIVARTFSTT
Mb2838c|M.bovis_AF2122/97 VQRRFGPPAPNRLWVADLTYVSTWAGF-AYVAFVTDAYARRILGWRVAST
Rv3475|M.tuberculosis_H37Rv VQRRFGPPAPNRLWVADLTYVSTWAGF-AYVAFVTDAYARRILGWRVAST
MAV_3271|M.avium_104 VHRNFAAAAPNQLWVTDLTFVPTWAGV-AYVCFIIDAHSRMIVGWRVASH
: * * : : *:* * * . : * :. : . .
Mvan_5060|M.vanbaalenii_PYR-1 MRTELVEQAVDAAVFTRG----GSVAGTILHSDRGSQYTSHDLAKACSDH
TH_4372|M.thermoresistible__bu MRTELVEAAVDAAVFTRA----GHVAGTVMHSDRGSQFTSYDMAQACTRH
Mflv_0608|M.gilvum_PYR-GCK MRTELVIDALKAAAALR-----GSLAGAIFHADHGSQYTSRDFANLCRDL
MAB_2088|M.abscessus_ATCC_1997 MKSRLATAALRNAVGRR-----GVVAGCVVHTDRGSQFRSRKFVQALHHH
MSMEG_1249|M.smegmatis_MC2_155 MKSSLAVAALEHAVALR-----SPVA-TIVHSDRGSQFRSRKFVHALSHN
MMAR_3786|M.marinum_M ADTALVNNAVNMAVDHR-----NRSGPTILHADHGTQFTSWSFGENMRRW
Mb2838c|M.bovis_AF2122/97 MATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEA
Rv3475|M.tuberculosis_H37Rv MATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEA
MAV_3271|M.avium_104 MRTSMVLDALEMARWSRG----TTLQDLICHSDAGSQFTSIRYGERLAEI
: :. *: * * : *:* *:*: * .
Mvan_5060|M.vanbaalenii_PYR-1 GLRRSMGATGICWDNAGSESLWSTVKHEYYK----RHAFTTYANLT-AGL
TH_4372|M.thermoresistible__bu GLLRSMGATGICWDNAGSESLWSTVKHEYYK----RHAFTTYANLT-AGL
Mflv_0608|M.gilvum_PYR-GCK GVVQSMGAVGSSADNALAESFNAALKREILQ----DRACWPDAAICRREV
MAB_2088|M.abscessus_ATCC_1997 GMVGSMGRVGAAGDNAAMESFFSLLQKNVLD----RRRWATREELRIAIV
MSMEG_1249|M.smegmatis_MC2_155 GLHGSMGRVGACGDNAAMESFFALLQRNVLD----RRRWTTRAELRLAIV
MMAR_3786|M.marinum_M GLLGSFGTVGDCFDNAAMESFWARLQVELLN----TRKWATTIELAAAMA
Mb2838c|M.bovis_AF2122/97 GIQPSVGAVGSSYDNALAETINGLYKTELIK-PGK--PWRSIEDVELATA
Rv3475|M.tuberculosis_H37Rv GIQPSVGAVGSSYDNALAETINGLYKTELIK-PGK--PWRSIEDVELATA
MAV_3271|M.avium_104 GAVPSIGTVGDSFDNALAETVNGYYKAELIYGPARSRPWKTVEDVELATL
* *.* .* . *** *:. . : : . :
Mvan_5060|M.vanbaalenii_PYR-1 DNYLHYYNHDRRHSSLGMISPIDFEIAARINQQSS-------
TH_4372|M.thermoresistible__bu DNYIRFYNHERRHSSLGMISPIDFDLSLDILLSTQV------
Mflv_0608|M.gilvum_PYR-GCK FRWLARYNTTRRHSYCRHSSPATYERNLTPATLPEAA-----
MAB_2088|M.abscessus_ATCC_1997 TWIERTYHRRRRQGALGRLTPVEYEAIMTTTASQAA------
MSMEG_1249|M.smegmatis_MC2_155 TWIERTYHRRRRQRALGRLTPIEFELLHTPVATAA-------
MMAR_3786|M.marinum_M DYIDNFYNIERRHSYLGNISPTEFETLWTSTYSIPQLA----
Mb2838c|M.bovis_AF2122/97 R-WVDWFNHRRLYQYCGDVPPVELEAAYYAQR--QRPAAG--
Rv3475|M.tuberculosis_H37Rv R-WVDWFNHRRLYQYCGDVPPVELEAAYYAQR--QRPAAG--
MAV_3271|M.avium_104 S-WVHWHNTSRLHSYLGDIPPTEFEAAFYDAYRTDQPLIGIQ
.: * .* :