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M. thermoresistible (build 8) TH_4360 (-)

annotation: amino acid adenylation domain
coordinates: 3529591 - 3531600
length: 670

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4360--100% (670)amino acid adenylation domain
M. thermoresistible (build 8)TH_3730-2e-9336.19% (699) PUTATIVE linear gramicidin synthetase subunit D
M. thermoresistible (build 8)TH_3141-7e-7032.21% (711) PUTATIVE amino acid adenylation domain

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2400cmbtF0.066.77% (674) peptide synthetase MBTF (peptide synthase)
M. gilvum PYR-GCKMflv_2697-0.063.54% (672) amino acid adenylation domain-containing protein
M. tuberculosis H37RvRv2379cmbtF0.066.77% (674) peptide synthetase MBTF (peptide synthase)
M. leprae Br4923MLBr_01051xclC5e-2025.69% (436) acyl-CoA synthetase
M. abscessus ATCC 19977MAB_2123-1e-14543.10% (703) putative peptide synthetase MbtF
M. marinum MMMAR_3690mbtF1e-15043.69% (705) non-ribosomal peptide synthetase MbtF
M. avium 104MAV_2014-0.062.17% (674) putative sulfotransferase
M. smegmatis MC2 155MSMEG_4510-0.066.27% (679) peptide synthetase mbtf
M. ulcerans Agy99MUL_3633mbtF1e-15043.71% (707) non-ribosomal peptide synthetase MbtF
M. vanbaalenii PYR-1Mvan_3844-0.057.82% (671) amino acid adenylation domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


TH_4360|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4510|M.smegmatis_MC2_155      -----MTATGTPPGIEDVLALSPLQQGLYSLAGLTEEDTG-----ADPYV
Mb2400c|M.bovis_AF2122/97           MGPVAVTRADARGAIDDVMALSPLQQGLFSRATLVAAESGSEAAEADPYV
Rv2379c|M.tuberculosis_H37Rv        MGPVAVTRADARGAIDDVMALSPLQQGLFSRATLVAAESGSEAAEADPYV
Mflv_2697|M.gilvum_PYR-GCK          ------MTAAKTGAIADVMALSPLQQGLYSLTAMSD--------GDDPYL
MAV_2014|M.avium_104                ---MTAAETDVAPDIEDVMALSPLQEGLYSLTTLAEFADGQ--PADDPYV
Mvan_3844|M.vanbaalenii_PYR-1       --MTQIQQSVEPPVIEDVLALSPLQQGLFSMATLSEGRD------DDPYV
MMAR_3690|M.marinum_M               -------MTAAAPQIEDVLALSPLQEGLFALHQLAEDG-------VDLYS
MUL_3633|M.ulcerans_Agy99           -------MTAAAPQIEDVLALTPLQEGLFALHQLAEDG-------VDLYS
MAB_2123|M.abscessus_ATCC_1997      -----MTGTEQQPQIEDVLALSPLQEGFFALSQLADES-------VDLYS
MLBr_01051|M.leprae_Br4923          --------------------------------------------------
                                                                                      

TH_4360|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4510|M.smegmatis_MC2_155      IAMAADIEGAVDPALLRSCAEAMLVRHPNLRASFFQGNLTRPVAVVPTAV
Mb2400c|M.bovis_AF2122/97           IAMAADAAGPLDIALLRDCAAAMLTRHPNLRASFLHGNLSRPVQVIPSSA
Rv2379c|M.tuberculosis_H37Rv        IAMAADAAGPLDIALLRDCAAAMLTRHPNLRASFLHGNLSRPVQVIPSSA
Mflv_2697|M.gilvum_PYR-GCK          IGMSADITGALDVSLLHDCAAAVLARHPNLRAGFFQGDLKRPVQVIPEKV
MAV_2014|M.avium_104                IGMAADITGTLDVALLRDCAEKMLVRHPNLRASFFSRGIPRPVQIVPSRV
Mvan_3844|M.vanbaalenii_PYR-1       IAMTADATGDLDARLLRECAAELLDRHANLRASFVKGNLSRAVQVIPKRV
MMAR_3690|M.marinum_M               MQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAAFWDRDVPKPVQIVPVHA
MUL_3633|M.ulcerans_Agy99           MQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAAFWDRDVPKPVQIVPVHA
MAB_2123|M.abscessus_ATCC_1997      MQFVADIDGGLDVDLLHRSAQALLTRHPNLRAAFWDRGLPKPVQIVPTHA
MLBr_01051|M.leprae_Br4923          --------------------------------------------------
                                                                                      

TH_4360|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4510|M.smegmatis_MC2_155      DLPWRHVTAPTAEAAAAIEAEERTRRFDLGRGPLIRFLLIEMPA-QRWRL
Mb2400c|M.bovis_AF2122/97           EVLWRHVRAHPSEVG-ALAAEERRRRFDVGRGPLIRFLLIELPD-ECWHL
Rv2379c|M.tuberculosis_H37Rv        EVLWRHVRAHPSEVG-ALAAEERRRRFDVGRGPLIRFLLIELPD-ECWHL
Mflv_2697|M.gilvum_PYR-GCK          EVLWRHVRCDGTEVE-PLEREERARRFDLGRGPAMRFLLLETGQ-QRWRF
MAV_2014|M.avium_104                ELPWRSVTASPAEVP-MLETAERRRPFDLERGPAIRFLLIELPD-AHWRL
Mvan_3844|M.vanbaalenii_PYR-1       DLPWRHVTVAGDAELEAAERLERTTPFTLARGPVIRFLLIEAP--QRWRF
MMAR_3690|M.marinum_M               ALPWSERVATPAEFD-SIARSERRRPFDLSRGPALRVVVLSVPGETKRRM
MUL_3633|M.ulcerans_Agy99           ALPWSERVATPAEFD-SIARSERRRPFDLSRGPALRVVVLSVPGETKRRM
MAB_2123|M.abscessus_ATCC_1997      DIPWEEREAQPTEFD-EIALRERLRPFNLGKGPAIRLVLLTVPGESRHRM
MLBr_01051|M.leprae_Br4923          --------------------------------------------------
                                                                                      

TH_4360|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4510|M.smegmatis_MC2_155      VVTAHHIAIDGWSLPVFVGEYITLYAADGDTAVFPAAPRPYRDYIGWLAG
Mb2400c|M.bovis_AF2122/97           VIVAHHIVIDGWSLPLFVSELLALYRAGGHVAALPAAPRPYRDYIGWLAG
Rv2379c|M.tuberculosis_H37Rv        VIVAHHIVIDGWSLPLFVSELLALYRAGGHVAALPAAPRPYRDYIGWLAG
Mflv_2697|M.gilvum_PYR-GCK          VITAHHIVIDGWSLSLLVSELLALYRAAGNTSALPDAPRPYRDYIGWLAA
MAV_2014|M.avium_104                VLTAHHIVIDGWSLPVFVNELMTLYRAGGDRSALPAAPRPYRDYIGWLAG
Mvan_3844|M.vanbaalenii_PYR-1       VVTAHHILIDGWSLPLFMGELLTLYRAGGDVTALPDPPRPYRDYIGWLAG
MMAR_3690|M.marinum_M               IFTAHHILVDGWSLAVFFTELLAVYRAGGAADALP-AARPYRDYIVWLAK
MUL_3633|M.ulcerans_Agy99           IFTAHHILVDGWSLAVFFTELLAVYRAGGAADALP-AARPYRDYIVWLAN
MAB_2123|M.abscessus_ATCC_1997      IVTSHHILMDGWAIAIFFSELLAVYQAGGSLAGLP-AVRPYRDYIAWLNA
MLBr_01051|M.leprae_Br4923          --------------------------------------------------
                                                                                      

TH_4360|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4510|M.smegmatis_MC2_155      RDHDASRARWRAHLDGLDGPTLLAPALSGREAEPG----LPARTEVTLDE
Mb2400c|M.bovis_AF2122/97           RDQTASRAMWADHLNGLDGPTLLSPALADTPVQPG----IPGRTEVRLDR
Rv2379c|M.tuberculosis_H37Rv        RDQTASRAMWADHLNGLDGPTLLSPALADTPVQPG----IPGRTEVRLDR
Mflv_2697|M.gilvum_PYR-GCK          RDQDHARSLWRAHLADLDGPTLLAPALGAATIGDG----LPGMVELTADP
MAV_2014|M.avium_104                RDLQASQRVWREHLAGLPGPTLLAASLGSAEATGGQRTALPRTTELRMPA
Mvan_3844|M.vanbaalenii_PYR-1       RDEETGRALWRRHLAGVDGPTLLTPALTSSAPTPG----RPRLTEVRLDA
MMAR_3690|M.marinum_M               QDRSAALAGWMDYLRGVSEP--LMVAYEATAGQS-----KPGKTELLLPA
MUL_3633|M.ulcerans_Agy99           QDRSAALAGWMDYLRGVSEP--LMVAYEATAGQS-----KPGKTELLLPA
MAB_2123|M.abscessus_ATCC_1997      QDTTEATARWTRYLGTVSGP--LMLADGAVAAHDN----VPEKSQFLLAP
MLBr_01051|M.leprae_Br4923          --------------------------------------------------
                                                                                      

TH_4360|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4510|M.smegmatis_MC2_155      QASAEIFDGARARGVTVNTLFQMAWAAILSAFTDRTDVVYGVTVSGRPDE
Mb2400c|M.bovis_AF2122/97           EATAELADAARTRGVTISTLVQMAWATTLSAFTGRGDVTFGVTVSGRPSE
Rv2379c|M.tuberculosis_H37Rv        EATAELADAARTRGVTISTLVQMAWATTLSAFTGRGDVTFGVTVSGRPSE
Mflv_2697|M.gilvum_PYR-GCK          SITEAVVDAARARGVTVNSLVQLAWALTLSSLTDRDDITFGVTVSGRPDD
MAV_2014|M.avium_104                EATARLAAETRSRGITVNTLMQMAWALVLSRLTDTRDVVFGVTVSGRPPE
Mvan_3844|M.vanbaalenii_PYR-1       ETTRQLAEAARSRGVTMNTLIQMAWATVLSVITDRTDVSFGVTVSGRPGE
MMAR_3690|M.marinum_M               ADTARLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQ
MUL_3633|M.ulcerans_Agy99           ADTARLRQWAGRHGLTLNTTVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQ
MAB_2123|M.abscessus_ATCC_1997      EETARLRQWAAANGLTLNTVTAFAWALVLGRLTDRTDVVFGTIVSGRPKE
MLBr_01051|M.leprae_Br4923          --------------------------------------------------
                                                                                      

TH_4360|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4510|M.smegmatis_MC2_155      LSGVESMVGLFINTVPLRIRLDPAGSVGEQCLAVQREAADLRDHSYLSHT
Mb2400c|M.bovis_AF2122/97           LSGVETMIGLFINTVPLRVRLDARATVGGQCAVLQRQFAMLRDHSYLGFN
Rv2379c|M.tuberculosis_H37Rv        LSGVETMIGLFINTVPLRVRLDARATVGGQCAVLQRQFAMLRDHSYLGFN
Mflv_2697|M.gilvum_PYR-GCK          LAGVESMIGLFVNTVPLRVRLDPALTAGAQCRALQQDAATLRDHSYLGHA
MAV_2014|M.avium_104                LTGVETMVGLFINTVPLRVRLDPAATVGEQCRAVQRDAALLREHSYLGHA
Mvan_3844|M.vanbaalenii_PYR-1       LAGVERMVGLFINTVPLRVRLDPAAPAGEQCLALQREAAALRDHGYLSHS
MMAR_3690|M.marinum_M               LPGVETMVGLFINAVPVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLS
MUL_3633|M.ulcerans_Agy99           LLGVETMVGLFINAVPVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLS
MAB_2123|M.abscessus_ATCC_1997      LPDVERMVGLFINSVPMVHHIDYSASVVEQCVQLQREAAAMRDIGYLSLS
MLBr_01051|M.leprae_Br4923          --------------------------------------------------
                                                                                      

TH_4360|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4510|M.smegmatis_MC2_155      EIRALGGIGELFDTLLVYENFPPGGLVGSDEFPLGSDGDGAVLRPSALES
Mb2400c|M.bovis_AF2122/97           EFRAIAGIGEMFDTLLVYENFPPGEVVGTAEFVAN----GVTFRPVALES
Rv2379c|M.tuberculosis_H37Rv        EFRAIAGIGEMFDTLLVYENFPPGEVVGTAEFVAN----GVTFRPVALES
Mflv_2697|M.gilvum_PYR-GCK          ELRALAGVGELFDTLLVYENFPPGAVAGAGTLEAA----GATFTPVALQS
MAV_2014|M.avium_104                QLRALGGIGEMFDTLLVYENFPMDGLTAGGELSAG----GATFRPSALQT
Mvan_3844|M.vanbaalenii_PYR-1       ELRALGGIGELFDTLLVYENFPPGGLVGQARFEAN----GATFVPSALES
MMAR_3690|M.marinum_M               EIQREHGRGPLFDSLFVFENAPIDDAIRPATTPDG-----AQFLPVEMES
MUL_3633|M.ulcerans_Agy99           EIQREHGRGPLFDSLFVFENAPIDDAIRPATTPDG-----AQFLPVEMES
MAB_2123|M.abscessus_ATCC_1997      TLQRAEGSAALFDTLFVFENAPIGDVVQEVEMADG-----ARFRPVEMES
MLBr_01051|M.leprae_Br4923          --------------------------------------------------
                                                                                      

TH_4360|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4510|M.smegmatis_MC2_155      LSHFPVTIAAHPTHGRLTVLVETLDGALGMLDPHALGRRVLTVVQRLLRS
Mb2400c|M.bovis_AF2122/97           LSHFPVTVAAHRSTGELTLLVEVLDGALGTMAPESLGRRVLAVLQRLVSR
Rv2379c|M.tuberculosis_H37Rv        LSHFPVTVAAHRSTGELTLLVEVLDGALGTMAPESLGRRVLAVLQRLVSR
Mflv_2697|M.gilvum_PYR-GCK          LAHFPVTIAAHLTDGRLTVLVEAKDGALGQITPRALGTRLLATVSRIVEG
MAV_2014|M.avium_104                LSHFPIAVAAHMEGGELVVLIEVVDGALGVIPADAVGRRLLTTAERLLRH
Mvan_3844|M.vanbaalenii_PYR-1       LSHFPVTIAAHLADDELTVFVEVIDGALGALRPGDLGRRVLHTAQRLISC
MMAR_3690|M.marinum_M               LTHYPLTVVSHLREDELLVLIEAIAEALPYLPAAEIGERMLTVLRQLPDI
MUL_3633|M.ulcerans_Agy99           LTHYPLTVVSHLREDELLVLIEAIAEALPYLPAAEIGERMLTVLRQLPDI
MAB_2123|M.abscessus_ATCC_1997      LAHYPLTVVSHMHGDSLLVLIEAIPQALPHVSGASVGERLVSVLRQLPDI
MLBr_01051|M.leprae_Br4923          --------------------------------------------------
                                                                                      

TH_4360|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4510|M.smegmatis_MC2_155      WDRPVRDVAVTLDDEVATVAP--TDTAVRP-GGFHTAFTEAAAQRLGSIA
Mb2400c|M.bovis_AF2122/97           WDRPLRDVDILLDGEHDPTAPGLPDVTTSA-PAVHTRFAEIAAAQPDSVA
Rv2379c|M.tuberculosis_H37Rv        WDRPLRDVDILLDGEHDPTAPGLPDVTTSA-PAVHTRFAEIAAAQPDSVA
Mflv_2697|M.gilvum_PYR-GCK          WDRPLREISISPDDHPVPVPVSEAAPTPSPSTGVHTRFTETASARLGSVA
MAV_2014|M.avium_104                WERPLRAVSVLFDDEAAPLRAAGPIAPPSP-KCLPARFADVVAQTPDAPA
Mvan_3844|M.vanbaalenii_PYR-1       WDAPLRSVGVLLPAEHTPAPMVREPLTANS---IHDRFAGIAGDRLGSVA
MMAR_3690|M.marinum_M               GDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQATPDAVA
MUL_3633|M.ulcerans_Agy99           GDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQTTPDAVA
MAB_2123|M.abscessus_ATCC_1997      GGGTPDALELLTARER-AEIVVTASAADPSVVSVWDLFEREAQAHPESLA
MLBr_01051|M.leprae_Br4923          --------------------------------MLLASLNPSVVTATDIAD
                                                                                      

TH_4360|M.thermoresistible__bu      -------------------------------------------------V
MSMEG_4510|M.smegmatis_MC2_155      LTWDGG----ELTYRQLDEAADRVAAELRRRGVGTETPVPIRLPRGPEYV
Mb2400c|M.bovis_AF2122/97           VSWADG----QLTYRELDALADRLATGLRRADVSRETPVAVALSRGPRYV
Rv2379c|M.tuberculosis_H37Rv        VSWADG----QLTYRELDALADRLATGLRRADVSRETPVAVALSRGPRYV
Mflv_2697|M.gilvum_PYR-GCK          LSWDGG----ALTYRQLDEAADRLAAVLTASGVRTETPVAVRLRRGADYV
MAV_2014|M.avium_104                VSWAQG----SLTYRELDEATNRLAAQLVALGVEPETPVAIKLSRGPRYV
Mvan_3844|M.vanbaalenii_PYR-1       LTWEAGGDSGTLTYRQLDEAADRMAVALTAAGVGPETSVAVLLSRGPDYV
MMAR_3690|M.marinum_M               LTAAAG---VRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSI
MUL_3633|M.ulcerans_Agy99           LAAAGG---VRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSI
MAB_2123|M.abscessus_ATCC_1997      LVADAG---TRYTYAQLRGAVSRLCAELIESGVTPETTVALALPRSADSI
MLBr_01051|M.leprae_Br4923          AVCVDG--------VVLSRSGLVGAATSVAERVGGARLVAVLATPTASTV
                                                                                     :

TH_4360|M.thermoresistible__bu      IAMLAILKAGGVIVPLDPSMPGHRIAEILRQTS----APIVVDQAVSDAV
MSMEG_4510|M.smegmatis_MC2_155      VAMLGVLKAGGLIVPLDPAMPDERVDEIIRQTHPDGRQPAIVDDAFVAAV
Mb2400c|M.bovis_AF2122/97           AAMLAVLKAGGMIVPLDPAMPGERVAEILRQTS----APVVIDEGVFAAS
Rv2379c|M.tuberculosis_H37Rv        AAMLAVLKAGGMIVPLDPAMPGERVAEILRQTS----APVVIDEGVFAAS
Mflv_2697|M.gilvum_PYR-GCK          VAMFAVLKAGGAIVPLDPAMPADRIEVILRRAG----VTVVVDEDTVARA
MAV_2014|M.avium_104                VAMLAVLKAGGMCVPMEPGMPAPRVNSILRQSG----ASIVLDEERIDEL
Mvan_3844|M.vanbaalenii_PYR-1       VTMLGVLKAGGVIVPLDPAMPAERISDILEQSR----ASVVVDDAFVAAV
MMAR_3690|M.marinum_M               VAILGVLAAGGAYLPVDVTLPSARVESIVRQAS----PALAITEADYSQL
MUL_3633|M.ulcerans_Agy99           VAILGVLAAGGAYLPVDVTLPSARVESIVRQAS----PALAITEADYSQL
MAB_2123|M.abscessus_ATCC_1997      IAILAVLAAGAAYVPVDIGLPAARVESILRQSN----PTLVITVDRHRDI
MLBr_01051|M.leprae_Br4923          LAITGCLIAGVPVVPVPADIGVVERRHMLTDSG---AQAWLGPGPSADSA
                                     :: . * **   :*:   :   .   ::  :      .           

TH_4360|M.thermoresistible__bu      RAS----SAAWSP---------------PPVHPGQAAYTVFTSGTTGVPK
MSMEG_4510|M.smegmatis_MC2_155      RAADAELPADYRP---------------AHVHPGQGAYIVFTSGTTGKPK
Mb2400c|M.bovis_AF2122/97           VGAD--ILEDDRA---------------ITVPVDQAAYVIFTSGTTGTPK
Rv2379c|M.tuberculosis_H37Rv        VGAD--ILEEDRA---------------ITVPVDQAAYVIFTSGTTGTPK
Mflv_2697|M.gilvum_PYR-GCK          TAEP---PAQYRP---------------AETLPGQAAYVVFTSGTTGEPK
MAV_2014|M.avium_104                LEAGRSQHGGFEP---------------PDIPPAQAAYVVFTSGTTGEPK
Mvan_3844|M.vanbaalenii_PYR-1       PDVEP--PAGYRP---------------AEVTADRAAYIVFTSGTTGRPK
MMAR_3690|M.marinum_M               VGTAVPTLALDDPAAVESISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPK
MUL_3633|M.ulcerans_Agy99           VGTAVPTLALDDPAAVDSISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPK
MAB_2123|M.abscessus_ATCC_1997      AGRGYQVLILDDPETAARISGRSESGHAVVVHRDQSAYLIFTSGSTGEPK
MLBr_01051|M.leprae_Br4923          PDGLPHIPVQLDARSWN---------RYPEPSPDATAMVIYTSGTTGPPK
                                                .                       *  ::***:** **

TH_4360|M.thermoresistible__bu      GVVGTHDALLAYADDHARNVLRPAAARLGRPLRIAHAWSFTFDAAWQPLA
MSMEG_4510|M.smegmatis_MC2_155      GVIGTHQALLAYAADHARNVLRPAAQRVGHPLRVAHAWSFTFDAAWQPLV
Mb2400c|M.bovis_AF2122/97           GVIGTHRALSAYADDHIERVLRPAAQRLGRPLRIAHAWSFTFDAAWQPLV
Rv2379c|M.tuberculosis_H37Rv        GVIGTHRALSAYADDHIERVLRPAAQRLGRPLRIAHAWSFTFDAAWQPLV
Mflv_2697|M.gilvum_PYR-GCK          GVIGTHRALLAYADDHIGAILRPAADRVGRPLRIAHAWSFTFDAAWQPLA
MAV_2014|M.avium_104                GVIGTHGAVGAYADDHLDRVLRPAAAALGRPLRIAHAWSFAFDAAWQPLV
Mvan_3844|M.vanbaalenii_PYR-1       GVVGTHGAVLGYAEDHAEQVLRPAAARIGRPLRVGHAWSFTFDAAWQPLA
MMAR_3690|M.marinum_M               GVVGTNAAVLSYFADHAERVYRAARARLGRPLRIAHAWSLSFDASWQPMV
MUL_3633|M.ulcerans_Agy99           GVAGTNAAVLSYFADHAERVYRAARARLGRPLRIAHAWSLSFDASWQPMV
MAB_2123|M.abscessus_ATCC_1997      GVVGTHAALMSYFADHRDRVYRPATARLGRKLRIAHAWSLSFDASWQPMI
MLBr_01051|M.leprae_Br4923          GVLLSRRAIAVDLDALAQAWQWTADDVLVHGLPLFHVHGLVLG----LLG
                                    **  :. *:             .*   : : * : *. .: :.     : 

TH_4360|M.thermoresistible__bu      ALFEGHAVHIIGDDVQRDAEALVDTIDRHRVDMIDITPSMFEQLRAFGLL
MSMEG_4510|M.smegmatis_MC2_155      ALLDGHANHIVGDDVQRDAEALVETIGRHAIDMIDTTPSMFTQLRAAGLL
Mb2400c|M.bovis_AF2122/97           ALLDGHAVHIVDDHRQRDAGALVEAIDRFGLDMIDTTPSMFAQLHNAGLL
Rv2379c|M.tuberculosis_H37Rv        ALLDGHAVHIVDDHRQRDAGALVEAIDRFGLDMIDTTPSMFAQLHNAGLL
Mflv_2697|M.gilvum_PYR-GCK          ALLDGHSVHIVDDATQRDAEALVDTIARFGVDMIDTTPSMFARLRDVGLL
MAV_2014|M.avium_104                ALLDGHGVHVVDEATQTDAEALVALIAEHGVDMIDTTPSMFAQLQAFGLL
Mvan_3844|M.vanbaalenii_PYR-1       ALLDGHSVHLLGEESQRDAEALVYRIGRFGIDMLDTTPSMFAQLHDVGLL
MMAR_3690|M.marinum_M               GLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAAGLL
MUL_3633|M.ulcerans_Agy99           GLLDGHEIHLFDADEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAAGLL
MAB_2123|M.abscessus_ATCC_1997      GLLDGHAVHLFDAEAMRDASLLVRGMAERGVDMIDTTPSMLAQLSAAGLL
MLBr_01051|M.leprae_Br4923          SLRIGNRFVHTG---KPTPTAYAQACSEAGGSLYFGVPTVWSRLVADEAV
                                    .*  *:     .      .   .        .:   .*::  :*     :

TH_4360|M.thermoresistible__bu      GRVP--LAVLALGGEAVGIGTWRFIRDECERTGMAAYNCYGPTETTVEAV
MSMEG_4510|M.smegmatis_MC2_155      STVP--LAVLALGGEAIDTALWQAIQAECERTWMSAHNCYGPTEATVEAV
Mb2400c|M.bovis_AF2122/97           DRAP--LAVLALGGEALGAATWRMIQQNCARTAMTAFNCYGPTETTVEAV
Rv2379c|M.tuberculosis_H37Rv        DRAP--LAVLALGGEALGAATWRMIQQNCARTAMTAFNCYGPTETTVEAV
Mflv_2697|M.gilvum_PYR-GCK          STVP--LAVLALGGEAVDPGLWQQIRQECARTGMSAFNCYGPTETTVEAV
MAV_2014|M.avium_104                SEAP--LTVLALGGEALGNAAWARIRNACNTTTMSAYNCYGPTETTVEAV
Mvan_3844|M.vanbaalenii_PYR-1       STVP--LAVLALGGEAVSPATWRLIGDECARTGMTAFNCYGPTETTVEAV
MMAR_3690|M.marinum_M               DHN---LSVLALGGEAINTGLWDQLR---GLSQMAVYNCYGPTEMTVEAV
MUL_3633|M.ulcerans_Agy99           DHN---LSVLALGGEAINTGLWDQLR---GLSQMAVYNCYGPTEMTVEAV
MAB_2123|M.abscessus_ATCC_1997      DHE---LAVLALGGEAIETALWDRLR---SLSDTAVYNCYGPTETTVEAV
MLBr_01051|M.leprae_Br4923          ARALRPARLLVSGSASLPVPVFDRLA---HLTGHRPIERYGSTESLITLS
                                            :*. *. ::    :  :      :     : **.**  :   

TH_4360|M.thermoresistible__bu      VGRFAAHEQPVIGLPTRHTRAYVLDAWLRPVPDG--VAGELYLAGAQLTR
MSMEG_4510|M.smegmatis_MC2_155      VAAIADHRDPCIGKPTDPTAAYVLDSWLRPVPAG--VAGELYLAGGQLTR
Mb2400c|M.bovis_AF2122/97           VAAVAEHARPVIGRPTCTTRAYVMDSWLRPVPDG--VAGELYLAGAQLTR
Rv2379c|M.tuberculosis_H37Rv        VAAVAEHARPVIGRPTCTTRAYVMDSWLRPVPDG--VAGELYLAGAQLTR
Mflv_2697|M.gilvum_PYR-GCK          VAEIGAHERPTIGRPTAPTRAYVLDSWLRPVPSG--AAGELYLAGGQLTR
MAV_2014|M.avium_104                VAAIAEHAEPSIGRPTRHTRGYVLDSELRPVPCG--ATGELYLGGAQLAR
Mvan_3844|M.vanbaalenii_PYR-1       VAPIDGYQRPSIGQPTRTMRTYVLDAWLRPVPDG--VAGELYLSGRQLTR
MMAR_3690|M.marinum_M               VAAVKDYRKPTIGTANAGTFGYVFDSALRMVPDG--VVGELYLSGAQLAR
MUL_3633|M.ulcerans_Agy99           VAAVKDYRKPTIGTANAGTFGYVFDSALRMVPDG--VVGELYLSGAQLAR
MAB_2123|M.abscessus_ATCC_1997      VAAVKEYPAPTIGTPNQGMVGYVLDSRLRPVPDG--AVGELYLAGAQLAR
MLBr_01051|M.leprae_Br4923          TLADGERRAGWVGLPLAGVQTRLVDESGGPVPYDGETVGRLQVRSPTMFG
                                    .          :* .       :.*     ** .  ..*.* : .  :  

TH_4360|M.thermoresistible__bu      GYLGRAGETATRFVPDPFDPGRRMYRTGDVVRRTADGALQYLGR-SDDQV
MSMEG_4510|M.smegmatis_MC2_155      GYVGRPGETAARFVADPFTLGARMYRTGDVVRRTPDGALQFLGR-SDDQV
Mb2400c|M.bovis_AF2122/97           GYLGRPAETAARFVAEPNGRGSRMYRTGDVVRRLPDGGLEFLGR-SDDQV
Rv2379c|M.tuberculosis_H37Rv        GYLGRPAETAARFVAEPNGRGSRMYRTGDVVRRLPDGGLEFLGR-SDDQV
Mflv_2697|M.gilvum_PYR-GCK          GYLGRPGETAARFVPDPFVPGARMYRTGDVVRRAVDGTLAFLGR-SDTQV
MAV_2014|M.avium_104                GYLGRAGETASRFVADPFAASERMYRTGDLVRRLPDGSLQYVGR-ADAQV
Mvan_3844|M.vanbaalenii_PYR-1       GYLGRAAETAGRFVADPFTPGQRMYRTGDVVRRGADGGLQFLGR-ADNQV
MMAR_3690|M.marinum_M               GYVGRPGMTAARFVADPLRPGQRMYRTGDLVRRLSHGGYAYVGR-ADTQV
MUL_3633|M.ulcerans_Agy99           GYVGRPGMTAARFVADPLRPGQRMYRTGDLVRRLSHGGYAYVGR-ADTQV
MAB_2123|M.abscessus_ATCC_1997      GYAGKPAVTAAAFVADPRRAGQRMYRTGDLVRRLPHGGFAYLGR-ADSQV
MLBr_01051|M.leprae_Br4923          GYLNRPEATAEAFDED------GWYRTGDVAVVDSGGMHRIVGRESVDLI
                                    ** .:.  **  *  :        *****:.     *    :** :   :

TH_4360|M.thermoresistible__bu      KIRGFRVEPGEVAAVLQTHPAVRAAHVA-VRRHRSGPRLVGYVATGGAEV
MSMEG_4510|M.smegmatis_MC2_155      KIRGFRVEPGEVAAALHRHPQVRHAHVA-LRRHRSGPRLVAYVVTDASLA
Mb2400c|M.bovis_AF2122/97           KIRGFRVEPGEIAAVLNGHHAVHGCHVT-ARGHASGPRLTAYVAGGPQPP
Rv2379c|M.tuberculosis_H37Rv        KIRGFRVEPGEIAAVLNGHHAVHGCHVT-ARGHASGPRLTAYVAGGPQPP
Mflv_2697|M.gilvum_PYR-GCK          KIRGFRVEPGEVAAVLRTHPAVGQAYVA-VRPHRDGHRLTAYVTGEPQ--
MAV_2014|M.avium_104                KIRGHRVEPGEIAAALESHPAVRHAGVL-VRHRDGAPRLTGYVATHEAAP
Mvan_3844|M.vanbaalenii_PYR-1       KIRGFRVEPGEIAAVLSGHPAVTDAHVV-VDRVGTQTRLIAYVAAATPPA
MMAR_3690|M.marinum_M               KIRGYRVEVGEIEAALRGQPGVHDAAVS-VLRQQDRTSLVGFVVWQDNMH
MUL_3633|M.ulcerans_Agy99           KIRGYRVEVGEIEAALRGQPGVHDAAVS-VLRQQDRTSLVGFVVWQDNMH
MAB_2123|M.abscessus_ATCC_1997      KIRGYRVEVGEIESALRLQPDIQTAAVT-VVRRAGGASLVGFVVCEKDTF
MLBr_01051|M.leprae_Br4923          KLGGYRIGAGEIEMALLGHPDVREVAVVGLPDEDLGQRIVAFVVGAEALD
                                    *: *.*:  **:  .*  :  :    *           : .:*.      

TH_4360|M.thermoresistible__bu      DVD---ELRRMLVARLPRYLVPHRVTVLDQLPLTPHGKIDDAALAAHDDA
MSMEG_4510|M.smegmatis_MC2_155      DAAG--ELRRMLAATLPRYLVPHHILLVDEIPLTTNGKVDDARLAALDSG
Mb2400c|M.bovis_AF2122/97           PVA---ELRAMLLERLPRYLVPHHIVVLDELPLTPHGKIDENALAAIN--
Rv2379c|M.tuberculosis_H37Rv        PVA---ELRAMLLERLPRYLVPHHIVVLDELPLTPHGKIDENALAAIN--
Mflv_2697|M.gilvum_PYR-GCK          --LR--ELRAWLGRRLPRYLMPNAIVAVDRIPLTAHGKIDEPALVALEP-
MAV_2014|M.avium_104                DTPSPAELRGMLSARLPRYMVPQRIIMVDEIPLTPNGKLDETALAAVDNA
Mvan_3844|M.vanbaalenii_PYR-1       VAD----LRELMAKRLPRYMVPQRVVVLDELPLTSHGKIDEAALAGIA--
MMAR_3690|M.marinum_M               EDLI--KLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLAED
MUL_3633|M.ulcerans_Agy99           EDLI--KLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLAED
MAB_2123|M.abscessus_ATCC_1997      DSAR--TMMR-LADRLPSYMMPSRLVPLPQLPVTVNGKLDGGALERLARE
MLBr_01051|M.leprae_Br4923          ADE----LINYVAQQLSIHKRPREVRFVDALPRNAMGKVLKKQLLFEG--
                                           :   :   *. :  *  :  :  :* .  **:    *      

TH_4360|M.thermoresistible__bu      ----TGSP-VAEPETPTEKALVEAVVDLLGPTPVDVDAELLSLGVDSIVA
MSMEG_4510|M.smegmatis_MC2_155      ----RQSGGFQGPATDTERVVAEVLAEVLDTRAVDVTAEFLDLGLDSIVA
Mb2400c|M.bovis_AF2122/97           ----VTEGPATPPQTPTELVLAEAFADVMETSNVDVTAGFLQMGLDSIVA
Rv2379c|M.tuberculosis_H37Rv        ----VTEGPATPPQTPTELVLAEAFADVMETSNVDVTAGFLQMGLDSIVA
Mflv_2697|M.gilvum_PYR-GCK          ----AADGAATRPQTPTEVELAAVLAEVLGVGEIDVTADFLELGLDSIVA
MAV_2014|M.avium_104                ----EAVDGAATPQTGTESALAELIAELLGQPRVDVTADFLALGLDSIMA
Mvan_3844|M.vanbaalenii_PYR-1       ----VEDAPSAAPETPTETALVELMAEVLGDDGIDVEADFLEMGLDSIVA
MMAR_3690|M.marinum_M               ALTSVSGGTAVSASTDTERVLCELFEEQLN-AVPHIDDDLFLFGMDSIVA
MUL_3633|M.ulcerans_Agy99           ALTSVSGGTAVSASTDTERVLCELFEEQLN-AVPHIDDDLFLFGMDSIVA
MAB_2123|M.abscessus_ATCC_1997      ALSGGAVGEQAQPATATECVLCECCAELFDGTAPGIDEDFFSLGVDSIVA
MLBr_01051|M.leprae_Br4923          --------------------------------------------------
                                                                                      

TH_4360|M.thermoresistible__bu      LSVVQAARRRGLALRARLMLECGSIRELAAAIDAEANAAPDTESADAGAG
MSMEG_4510|M.smegmatis_MC2_155      LTVVQAVRRRGLALRARLMLECANVRELAAAIDADAHHAAVDHTPEDSG-
Mb2400c|M.bovis_AF2122/97           LSVVQAARRRGIALRARLMVECDTIRELAAAIDSDAAWQAPAN----DAG
Rv2379c|M.tuberculosis_H37Rv        LSVVQAARRRGIALRARLMVECDTIRELAAAIDSDAAWQAPAN----DAG
Mflv_2697|M.gilvum_PYR-GCK          LSVVQTARRRGVVMRAKLMLDCATVRELAAAIDDAGSGPPSAD----EGS
MAV_2014|M.avium_104                LSVVQAARARGIALRARLVLDCTSIRELAEAIDAESTPAAGEVD---DGT
Mvan_3844|M.vanbaalenii_PYR-1       LTLVQAARRRGLEMRARLMLECNTIRELATAIDSGAHDHAPAAVT-DDRF
MMAR_3690|M.marinum_M               ISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPAD---ADY
MUL_3633|M.ulcerans_Agy99           ISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPAD---ADY
MAB_2123|M.abscessus_ATCC_1997      ISLVNKARKRDLVITPRMVLAAPTIRQLAALVDTRGHVDSLAGE---ADY
MLBr_01051|M.leprae_Br4923          --------------------------------------------------
                                                                                      

TH_4360|M.thermoresistible__bu      EPIPVLPAVHWLYQHGDPRRLAQTEAIRLPDGITGADLRTLLTTVVASHE
MSMEG_4510|M.smegmatis_MC2_155      -PIPLLPNGSWLYQYGEPRRLAQTEAFRLPEGTTAAQLRTLLRTVVDGHE
Mb2400c|M.bovis_AF2122/97           EPIPVLPNTHWLYEYGDPRRLAQTEVIRLPDRITRERLDAVLAAVVDGHE
Rv2379c|M.tuberculosis_H37Rv        EPIPVLPNTHWLYEYGDPRRLAQTEVIRLPDRITRERLDAVLAAVVDGHE
Mflv_2697|M.gilvum_PYR-GCK          GPIALLPNAHWLYEFGDPRRLASTEALRLPRGITGPQIRALLQSVVDAHP
MAV_2014|M.avium_104                GPMPLLPNGRWLYEHGQPRRLAQTEAIRVPQTLRRDQLETALAGIIDGHE
Mvan_3844|M.vanbaalenii_PYR-1       GEVMPAPIMSWMYECGNYRRFTQNVLVSLPADITDSRLEQILQALLDRHD
MMAR_3690|M.marinum_M               GAVRPLPMVSWLYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHD
MUL_3633|M.ulcerans_Agy99           GAVLPLPMVSWLYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHD
MAB_2123|M.abscessus_ATCC_1997      GEVPPLPVVSWMYESEIYRRLSLSVLVRLPAGIDRPGIERMLQLLLDGFT
MLBr_01051|M.leprae_Br4923          --------------------------------------------------
                                                                                      

TH_4360|M.thermoresistible__bu      VLRTRLDR--TTMTLVPQHDGDIGDRLREVTVR------GDLTAAVAEQV
MSMEG_4510|M.smegmatis_MC2_155      VLRTRLDR--VTRTLVPHGP---RDVLTEAVGV------GTLADAVAEQA
Mb2400c|M.bovis_AF2122/97           VLRCRFDR--DAMALVAQPK---TDILSEVWVS------GELVTAVAEQT
Rv2379c|M.tuberculosis_H37Rv        VLRCRFDR--DAMALVAQPK---TDILSEVWVS------GELVTAVAEQT
Mflv_2697|M.gilvum_PYR-GCK          VLRTRLDR--AAMTLVDGGF---DLPLTEIEVG------DEGSAAVARHA
MAV_2014|M.avium_104                VLRSRVDR--ATMTLVPGPAPDIGKELEEVAVV------GDLRAAVADRA
Mvan_3844|M.vanbaalenii_PYR-1       MLRAILD---ERGRLVTRPPGAVRVADVLRVVD------AAAHTVLAAEV
MMAR_3690|M.marinum_M               TLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAA
MUL_3633|M.ulcerans_Agy99           TLRSILTETPEGPRLVTREPAAVRAEDVLTRIRLPEGSDDELASAVAHAA
MAB_2123|M.abscessus_ATCC_1997      MLRSTLVDTPDGARVVTREPGVVRGESVLSRVELPTG--ESAHAAITNAA
MLBr_01051|M.leprae_Br4923          --------------------------------------------------
                                                                                      

TH_4360|M.thermoresistible__bu      DLSVRTLDPEGGRLWSAVWLR---PEQGPG-VLVWTAHVIAMDPASWRVV
MSMEG_4510|M.smegmatis_MC2_155      ALSVDRIDPQQGSMLDAVWLR---HPDAPGGVFILTAHVLALDPASWRIV
Mb2400c|M.bovis_AF2122/97           LGVLASLDPQAGRLLSAVWLR---EPDGPG-VLVLTAHVLAMDPASWRIV
Rv2379c|M.tuberculosis_H37Rv        LGALASLDPQAGRLLSAVWLR---EPDGPG-VLVLTAHVLAMDPASWRIV
Mflv_2697|M.gilvum_PYR-GCK          AAALEHLDPQRGPLWGAVWLRGSDDADSTSSVLLLTAHVLAMDPVSWQIV
MAV_2014|M.avium_104                ARAIDRLDPERGVLLGAVWLR---PADGDG-VLLLTAHVIALDPASWRVV
Mvan_3844|M.vanbaalenii_PYR-1       VAALDRIDPTSGAMVQAVWFR-----HGPP-VLALCVHHLSTDVVSWYLI
MMAR_3690|M.marinum_M               RVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIM
MUL_3633|M.ulcerans_Agy99           RVVTDQIDPSAGAMVRAIWFRGTEHRADPANMLLLTAHHLAVDVVSWHIM
MAB_2123|M.abscessus_ATCC_1997      RQAFDSLDPRSGAMMRAVWLAS----RDSGDVLLLTVHHLAMDVVSWHIV
MLBr_01051|M.leprae_Br4923          --------------------------------------------------
                                                                                      

TH_4360|M.thermoresistible__bu      LGDLDAGWHALSAGRPS---------------------------------
MSMEG_4510|M.smegmatis_MC2_155      VGELETAWHALASGREPTPVREHTSLRRWSRMLSERALKLDT---VDFWH
Mb2400c|M.bovis_AF2122/97           LGELDAGLHALAAGRAPSPARENTSYRQWSRLLAQRAKALDS---VDFWV
Rv2379c|M.tuberculosis_H37Rv        LGELDAGLHALAAGRAPSPARENTSYRQWSRLLAQRAKALDS---VDFWV
Mflv_2697|M.gilvum_PYR-GCK          IGELDAGWHALAGGRAPAALGEHTGYRQWSNLLRERAESSDG---LQFWL
MAV_2014|M.avium_104                LGELGAALTAAATGHSPAAVREHTSYRRWAHALTARAHRLDT---VGFWA
Mvan_3844|M.vanbaalenii_PYR-1       LGALAQIDATLAAGHAPDPAAEYTTYREWTRRLYQRSRTEAVERRRGFWV
MMAR_3690|M.marinum_M               LGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYWA
MUL_3633|M.ulcerans_Agy99           LGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYWA
MAB_2123|M.abscessus_ATCC_1997      LGYLADAWIAVRSGTAPKAPMEFTSYRQWSQLMHQRASSHDVLRQRDYWA
MLBr_01051|M.leprae_Br4923          --------------------------------------------------
                                                                                      

TH_4360|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4510|M.smegmatis_MC2_155      RQFDGADPDIGARRVDPATDRMRDIAVEMTFADADLTARLLT----GGVP
Mb2400c|M.bovis_AF2122/97           AELEGADPPLGARRVAPQTDRVGELAITMSISDADLTARLLS----TGRS
Rv2379c|M.tuberculosis_H37Rv        AELEGADPPLGARRVAPQTDRVGELAITMSISDADLTARLLS----TGRS
Mflv_2697|M.gilvum_PYR-GCK          DQLGGPDPALGARRVRPDTDRAGDVRVTVTVTGADVTARLLA----GPHP
MAV_2014|M.avium_104                SELDGDDPDLGARRVDPARDRARDLLVRNVATDADLTRRLLE----SGLP
Mvan_3844|M.vanbaalenii_PYR-1       EQLAGSDPLLGRRLPDPRHDTWSTLQSTDVVTDAGATRAILDRLDGASLE
MMAR_3690|M.marinum_M               ALVREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVR-RDQG
MUL_3633|M.ulcerans_Agy99           ALVREPDPELGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVR-RDQG
MAB_2123|M.abscessus_ATCC_1997      EQVSGADPELGSRHADPSRDTWGTLQTTAVPTPVAVTTRLLASLN-KPEG
MLBr_01051|M.leprae_Br4923          --------------------------------------------------
                                                                                      

TH_4360|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4510|M.smegmatis_MC2_155      VTEVLAAATARTVTAWRRERGQPTPA-PLLALETHGRADAVVSADLGEDP
Mb2400c|M.bovis_AF2122/97           MTDLLATAAARMVTAWRRQRGQQTPA-PLLALETHGRADVHVDK------
Rv2379c|M.tuberculosis_H37Rv        MTDLLATAAARMVTAWRRQRGQQTPA-PLLALETHGRADVHVDK------
Mflv_2697|M.gilvum_PYR-GCK          VLDVLVAALGRTITEWRGRRNQPTPP-PLVALETHGRA-ALAEADTADTA
MAV_2014|M.avium_104                LPTLLVAATAATVTRWRRQRGQSTPP-PLLALETHGRADSLVDG---PGA
Mvan_3844|M.vanbaalenii_PYR-1       VRDFLLTALTLTLASWRIERGQPAHHGALVALEGHGREDALVGG------
MMAR_3690|M.marinum_M               VRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDT------
MUL_3633|M.ulcerans_Agy99           VRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDT------
MAB_2123|M.abscessus_ATCC_1997      VYSFLLSALAVTVASWRKLRGQDSTAGTLVSLEGHGRADGELDT------
MLBr_01051|M.leprae_Br4923          --------------------------------------------------
                                                                                      

TH_4360|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4510|M.smegmatis_MC2_155      HQVDTGDTAGLLSMIYPLRVTAGDA------------------RGVAELV
Mb2400c|M.bovis_AF2122/97           -TADTSDTVGLLSAIYPLRIHCDGA------------------TDFAR--
Rv2379c|M.tuberculosis_H37Rv        -TADTSDTVGLLSAIYPLRIHCDGA------------------TDFAR--
Mflv_2697|M.gilvum_PYR-GCK          DTADTSDTVGLLSAIYPLRLHEDSP------------------GATTELI
MAV_2014|M.avium_104                HTIDTGDTVGLLSSIYPIRVDAADP------------------RRVADKL
Mvan_3844|M.vanbaalenii_PYR-1       -GVDTSATVGWFTSVYPVRLGAGEAAIDVDTAARNPAAARSLLRAVIQQL
MMAR_3690|M.marinum_M               ---DTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHL
MUL_3633|M.ulcerans_Agy99           ---DTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHL
MAB_2123|M.abscessus_ATCC_1997      ---DTSGTVGWFTTVYPVRVAAGEAAIDVDRMENDVNAARQLLAGVARHI
MLBr_01051|M.leprae_Br4923          --------------------------------------------------
                                                                                      

TH_4360|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4510|M.smegmatis_MC2_155      AAIPGDPIDYGLLRHLREDTAESLGVHRDPQLLLNYLGRIELDSADH---
Mb2400c|M.bovis_AF2122/97           --IPGSGIDYGLLRYLRADTAERLRAHREPQLLLNYLGSLHVGVG-----
Rv2379c|M.tuberculosis_H37Rv        --IPGSGIDYGLLRYLRADTAERLRAHREPQLLLNYLGSLHVGVG-----
Mflv_2697|M.gilvum_PYR-GCK          AGVPAGGIDYGLLRYLRPDTSEVLKAHPEPQILLNYLGRTDLVPSG----
MAV_2014|M.avium_104                AAIPGDGLDYGLLRYLRDDTAERLAALPSPQLLLNYLGAAHTDGGT----
Mvan_3844|M.vanbaalenii_PYR-1       AEVPDKGLDYGLLRYTRRD--ETLRALPEPQVEFNYIGRYDLSADQTSQA
MMAR_3690|M.marinum_M               EAIPNDGLDYGLLRY--VDGVAELVDAVDPQIQFSYLGRLDLGGVADQP-
MUL_3633|M.ulcerans_Agy99           EAIPNDGLDYGLLRY--VDGVAELVDAVDPQIQFSYLGRLDLGGVADQP-
MAB_2123|M.abscessus_ATCC_1997      DEIPYQGLDYGLLRY--VRGCEELSSARDPQIQFNYVGRMDISGIDDQP-
MLBr_01051|M.leprae_Br4923          --------------------------------------------------
                                                                                      

TH_4360|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4510|M.smegmatis_MC2_155      -ALLQDRSLLSGVTPIPEPDVAVRHELTIMAAVIDRDGSAVLGAQWRTLP
Mb2400c|M.bovis_AF2122/97           -DLAVDRALLADVGQLPEPEQPVRHELTVLAALLGPADAPVLATRWRTLP
Rv2379c|M.tuberculosis_H37Rv        -DLAVDRALLADVGQLPEPEQPVRHELTVLAALLGPADAPVLATRWRTLP
Mflv_2697|M.gilvum_PYR-GCK          -AIVADRLLLSGLSTVPEPNAAVRHELTVVAAVVAHGDEPALVAQWRVLP
MAV_2014|M.avium_104                -GLTLERELLAGLSPIPEPDLAVRHELTIAAMVLTYGGQRVLAAQWRTLP
Mvan_3844|M.vanbaalenii_PYR-1       WSLITDETLNAHMPAAAEPDLPLRYTFDVISVISGGADGPQLRTSWRWST
MMAR_3690|M.marinum_M               -WSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSD
MUL_3633|M.ulcerans_Agy99           -WSLLTGPYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSD
MAB_2123|M.abscessus_ATCC_1997      -WSLITDARSLAVPPDSEPDLPLRFAINIGSAVMTTPEGPQLLTNWQLSS
MLBr_01051|M.leprae_Br4923          --------------------------------------------------
                                                                                      

TH_4360|M.thermoresistible__bu      ----------------------------
MSMEG_4510|M.smegmatis_MC2_155      DILSAAEVGTLQTMWLDALREVVE----
Mb2400c|M.bovis_AF2122/97           DILSADDVATLQSLWQGALAEITA----
Rv2379c|M.tuberculosis_H37Rv        DILSADDVATLQSLWQGALAEITA----
Mflv_2697|M.gilvum_PYR-GCK          EILSDTDVEEMQTIWQDTLREVL-----
MAV_2014|M.avium_104                DILTDTDITALQELWVDSLREMVT----
Mvan_3844|M.vanbaalenii_PYR-1       ALSTSTEVDRLTALWQQAVTVLGEAL--
MMAR_3690|M.marinum_M               AVFERSDIDHLTGLWQRGIAALAAGLD-
MUL_3633|M.ulcerans_Agy99           AVFERSDIDHLTGLWQRGIAALAAGLD-
MAB_2123|M.abscessus_ATCC_1997      ALFTPADASRLAQLWQRSVAALAGALDG
MLBr_01051|M.leprae_Br4923          ----------------------------