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MGPVAVTRADARGAIDDVMALSPLQQGLFSRATLVAAESGSEAAEADPYVIAMAADAAGPLDIALLRDCA AAMLTRHPNLRASFLHGNLSRPVQVIPSSAEVLWRHVRAHPSEVGALAAEERRRRFDVGRGPLIRFLLIE LPDECWHLVIVAHHIVIDGWSLPLFVSELLALYRAGGHVAALPAAPRPYRDYIGWLAGRDQTASRAMWAD HLNGLDGPTLLSPALADTPVQPGIPGRTEVRLDREATAELADAARTRGVTISTLVQMAWATTLSAFTGRG DVTFGVTVSGRPSELSGVETMIGLFINTVPLRVRLDARATVGGQCAVLQRQFAMLRDHSYLGFNEFRAIA GIGEMFDTLLVYENFPPGEVVGTAEFVANGVTFRPVALESLSHFPVTVAAHRSTGELTLLVEVLDGALGT MAPESLGRRVLAVLQRLVSRWDRPLRDVDILLDGEHDPTAPGLPDVTTSAPAVHTRFAEIAAAQPDSVAV SWADGQLTYRELDALADRLATGLRRADVSRETPVAVALSRGPRYVAAMLAVLKAGGMIVPLDPAMPGERV AEILRQTSAPVVIDEGVFAASVGADILEDDRAITVPVDQAAYVIFTSGTTGTPKGVIGTHRALSAYADDH IERVLRPAAQRLGRPLRIAHAWSFTFDAAWQPLVALLDGHAVHIVDDHRQRDAGALVEAIDRFGLDMIDT TPSMFAQLHNAGLLDRAPLAVLALGGEALGAATWRMIQQNCARTAMTAFNCYGPTETTVEAVVAAVAEHA RPVIGRPTCTTRAYVMDSWLRPVPDGVAGELYLAGAQLTRGYLGRPAETAARFVAEPNGRGSRMYRTGDV VRRLPDGGLEFLGRSDDQVKIRGFRVEPGEIAAVLNGHHAVHGCHVTARGHASGPRLTAYVAGGPQPPPV AELRAMLLERLPRYLVPHHIVVLDELPLTPHGKIDENALAAINVTEGPATPPQTPTELVLAEAFADVMET SNVDVTAGFLQMGLDSIVALSVVQAARRRGIALRARLMVECDTIRELAAAIDSDAAWQAPANDAGEPIPV LPNTHWLYEYGDPRRLAQTEVIRLPDRITRERLDAVLAAVVDGHEVLRCRFDRDAMALVAQPKTDILSEV WVSGELVTAVAEQTLGVLASLDPQAGRLLSAVWLREPDGPGVLVLTAHVLAMDPASWRIVLGELDAGLHA LAAGRAPSPARENTSYRQWSRLLAQRAKALDSVDFWVAELEGADPPLGARRVAPQTDRVGELAITMSISD ADLTARLLSTGRSMTDLLATAAARMVTAWRRQRGQQTPAPLLALETHGRADVHVDKTADTSDTVGLLSAI YPLRIHCDGATDFARIPGSGIDYGLLRYLRADTAERLRAHREPQLLLNYLGSLHVGVGDLAVDRALLADV GQLPEPEQPVRHELTVLAALLGPADAPVLATRWRTLPDILSADDVATLQSLWQGALAEITA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2400c | mbtF | - | 100% (1461) | peptide synthetase MBTF (peptide synthase) |
| M. bovis AF2122 / 97 | Mb0104 | nrp | 1e-94 | 31.57% (1042) | peptide synthetase |
| M. bovis AF2122 / 97 | Mb2401c | mbtE | 5e-84 | 26.65% (1336) | peptide synthetase MBTE (peptide synthase) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2697 | - | 0.0 | 61.02% (1465) | amino acid adenylation domain-containing protein |
| M. tuberculosis H37Rv | Rv2379c | mbtF | 0.0 | 99.86% (1461) | peptide synthetase MBTF (peptide synthase) |
| M. leprae Br4923 | MLBr_02353 | - | 1e-27 | 27.41% (456) | polyketide synthase |
| M. abscessus ATCC 19977 | MAB_2123 | - | 0.0 | 41.73% (1524) | putative peptide synthetase MbtF |
| M. marinum M | MMAR_3690 | mbtF | 0.0 | 42.05% (1529) | non-ribosomal peptide synthetase MbtF |
| M. avium 104 | MAV_2014 | - | 0.0 | 59.46% (1485) | putative sulfotransferase |
| M. smegmatis MC2 155 | MSMEG_4510 | - | 0.0 | 61.92% (1476) | peptide synthetase mbtf |
| M. thermoresistible (build 8) | TH_4360 | - | 0.0 | 66.77% (674) | PUTATIVE amino acid adenylation domain |
| M. ulcerans Agy99 | MUL_3633 | mbtF | 0.0 | 42.16% (1530) | non-ribosomal peptide synthetase MbtF |
| M. vanbaalenii PYR-1 | Mvan_3844 | - | 0.0 | 55.44% (1490) | amino acid adenylation domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2400c|M.bovis_AF2122/97 MGPVAVTRADARGAIDDVMALSPLQQGLFSRATLVAAESGSEAAEADPYV
Rv2379c|M.tuberculosis_H37Rv MGPVAVTRADARGAIDDVMALSPLQQGLFSRATLVAAESGSEAAEADPYV
MSMEG_4510|M.smegmatis_MC2_155 -----MTATGTPPGIEDVLALSPLQQGLYSLAGLTEEDTG-----ADPYV
TH_4360|M.thermoresistible__bu --------------------------------------------------
MAV_2014|M.avium_104 ---MTAAETDVAPDIEDVMALSPLQEGLYSLTTLAEFADGQ--PADDPYV
Mflv_2697|M.gilvum_PYR-GCK ------MTAAKTGAIADVMALSPLQQGLYSLTAMSD--------GDDPYL
Mvan_3844|M.vanbaalenii_PYR-1 --MTQIQQSVEPPVIEDVLALSPLQQGLFSMATLSEGRD------DDPYV
MMAR_3690|M.marinum_M -------MTAAAPQIEDVLALSPLQEGLFALHQLAEDG-------VDLYS
MUL_3633|M.ulcerans_Agy99 -------MTAAAPQIEDVLALTPLQEGLFALHQLAEDG-------VDLYS
MAB_2123|M.abscessus_ATCC_1997 -----MTGTEQQPQIEDVLALSPLQEGFFALSQLADES-------VDLYS
MLBr_02353|M.leprae_Br4923 -----MITPDNAIAVVGMAGKFPGANDVSAFWTNLRRGKESIVTLSEQEL
Mb2400c|M.bovis_AF2122/97 IAMAADAAGPLDIALLRDCAAAMLTRHPNLRASFLHGNLSRPVQVIPSSA
Rv2379c|M.tuberculosis_H37Rv IAMAADAAGPLDIALLRDCAAAMLTRHPNLRASFLHGNLSRPVQVIPSSA
MSMEG_4510|M.smegmatis_MC2_155 IAMAADIEGAVDPALLRSCAEAMLVRHPNLRASFFQGNLTRPVAVVPTAV
TH_4360|M.thermoresistible__bu --------------------------------------------------
MAV_2014|M.avium_104 IGMAADITGTLDVALLRDCAEKMLVRHPNLRASFFSRGIPRPVQIVPSRV
Mflv_2697|M.gilvum_PYR-GCK IGMSADITGALDVSLLHDCAAAVLARHPNLRAGFFQGDLKRPVQVIPEKV
Mvan_3844|M.vanbaalenii_PYR-1 IAMTADATGDLDARLLRECAAELLDRHANLRASFVKGNLSRAVQVIPKRV
MMAR_3690|M.marinum_M MQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAAFWDRDVPKPVQIVPVHA
MUL_3633|M.ulcerans_Agy99 MQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAAFWDRDVPKPVQIVPVHA
MAB_2123|M.abscessus_ATCC_1997 MQFVADIDGGLDVDLLHRSAQALLTRHPNLRAAFWDRGLPKPVQIVPTHA
MLBr_02353|M.leprae_Br4923 RDNGVSDKALADPAYVRR--APLLDGIDEFDADFFG-LPPLAAQVLDPQH
Mb2400c|M.bovis_AF2122/97 EVLWRHVRAHPSEVG-ALAAEERRRRFDVGRGPLIRFLLIELPD-ECWHL
Rv2379c|M.tuberculosis_H37Rv EVLWRHVRAHPSEVG-ALAAEERRRRFDVGRGPLIRFLLIELPD-ECWHL
MSMEG_4510|M.smegmatis_MC2_155 DLPWRHVTAPTAEAAAAIEAEERTRRFDLGRGPLIRFLLIEMPA-QRWRL
TH_4360|M.thermoresistible__bu --------------------------------------------------
MAV_2014|M.avium_104 ELPWRSVTASPAEVP-MLETAERRRPFDLERGPAIRFLLIELPD-AHWRL
Mflv_2697|M.gilvum_PYR-GCK EVLWRHVRCDGTEVE-PLEREERARRFDLGRGPAMRFLLLETGQ-QRWRF
Mvan_3844|M.vanbaalenii_PYR-1 DLPWRHVTVAGDAELEAAERLERTTPFTLARGPVIRFLLIEAP--QRWRF
MMAR_3690|M.marinum_M ALPWSERVATPAEFD-SIARSERRRPFDLSRGPALRVVVLSVPGETKRRM
MUL_3633|M.ulcerans_Agy99 ALPWSERVATPAEFD-SIARSERRRPFDLSRGPALRVVVLSVPGETKRRM
MAB_2123|M.abscessus_ATCC_1997 DIPWEEREAQPTEFD-EIALRERLRPFNLGKGPAIRLVLLTVPGESRHRM
MLBr_02353|M.leprae_Br4923 RLFLQCAWHALEDAG--CDPAQFDGSIGVYGTSSPSGYLLHNLLSHRDPH
Mb2400c|M.bovis_AF2122/97 VIVAHHIVIDGWSLPLFVSELLALYRAGGHVAALPAAPRPYRDYIGWLAG
Rv2379c|M.tuberculosis_H37Rv VIVAHHIVIDGWSLPLFVSELLALYRAGGHVAALPAAPRPYRDYIGWLAG
MSMEG_4510|M.smegmatis_MC2_155 VVTAHHIAIDGWSLPVFVGEYITLYAADGDTAVFPAAPRPYRDYIGWLAG
TH_4360|M.thermoresistible__bu --------------------------------------------------
MAV_2014|M.avium_104 VLTAHHIVIDGWSLPVFVNELMTLYRAGGDRSALPAAPRPYRDYIGWLAG
Mflv_2697|M.gilvum_PYR-GCK VITAHHIVIDGWSLSLLVSELLALYRAAGNTSALPDAPRPYRDYIGWLAA
Mvan_3844|M.vanbaalenii_PYR-1 VVTAHHILIDGWSLPLFMGELLTLYRAGGDVTALPDPPRPYRDYIGWLAG
MMAR_3690|M.marinum_M IFTAHHILVDGWSLAVFFTELLAVYRAGGAADALP-AARPYRDYIVWLAK
MUL_3633|M.ulcerans_Agy99 IFTAHHILVDGWSLAVFFTELLAVYRAGGAADALP-AARPYRDYIVWLAN
MAB_2123|M.abscessus_ATCC_1997 IVTSHHILMDGWAIAIFFSELLAVYQAGGSLAGLP-AVRPYRDYIAWLNA
MLBr_02353|M.leprae_Br4923 TVLAEGLNFDQFSLFLQNDKDFLATRISHAFNLRGPSIAVQTACSSSLVA
Mb2400c|M.bovis_AF2122/97 RDQTASRAMWADHLNGLDGPTLLSPALADTPVQPG----IPGRTEVRLDR
Rv2379c|M.tuberculosis_H37Rv RDQTASRAMWADHLNGLDGPTLLSPALADTPVQPG----IPGRTEVRLDR
MSMEG_4510|M.smegmatis_MC2_155 RDHDASRARWRAHLDGLDGPTLLAPALSGREAEPG----LPARTEVTLDE
TH_4360|M.thermoresistible__bu --------------------------------------------------
MAV_2014|M.avium_104 RDLQASQRVWREHLAGLPGPTLLAASLGSAEATGGQRTALPRTTELRMPA
Mflv_2697|M.gilvum_PYR-GCK RDQDHARSLWRAHLADLDGPTLLAPALGAATIGDG----LPGMVELTADP
Mvan_3844|M.vanbaalenii_PYR-1 RDEETGRALWRRHLAGVDGPTLLTPALTSSAPTPG----RPRLTEVRLDA
MMAR_3690|M.marinum_M QDRSAALAGWMDYLRGVSEP--LMVAYEATAGQS-----KPGKTELLLPA
MUL_3633|M.ulcerans_Agy99 QDRSAALAGWMDYLRGVSEP--LMVAYEATAGQS-----KPGKTELLLPA
MAB_2123|M.abscessus_ATCC_1997 QDTTEATARWTRYLGTVSGP--LMLADGAVAAHDN----VPEKSQFLLAP
MLBr_02353|M.leprae_Br4923 LHLACLSLLSGECDMALAGGSSLCIPHRVGYWHSP----------GSMVS
Mb2400c|M.bovis_AF2122/97 EATAELADAARTRGVTISTLVQMAWATTLSAFTGRGDVTFGVTVSGRPSE
Rv2379c|M.tuberculosis_H37Rv EATAELADAARTRGVTISTLVQMAWATTLSAFTGRGDVTFGVTVSGRPSE
MSMEG_4510|M.smegmatis_MC2_155 QASAEIFDGARARGVTVNTLFQMAWAAILSAFTDRTDVVYGVTVSGRPDE
TH_4360|M.thermoresistible__bu --------------------------------------------------
MAV_2014|M.avium_104 EATARLAAETRSRGITVNTLMQMAWALVLSRLTDTRDVVFGVTVSGRPPE
Mflv_2697|M.gilvum_PYR-GCK SITEAVVDAARARGVTVNSLVQLAWALTLSSLTDRDDITFGVTVSGRPDD
Mvan_3844|M.vanbaalenii_PYR-1 ETTRQLAEAARSRGVTMNTLIQMAWATVLSVITDRTDVSFGVTVSGRPGE
MMAR_3690|M.marinum_M ADTARLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQ
MUL_3633|M.ulcerans_Agy99 ADTARLRQWAGRHGLTLNTTVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQ
MAB_2123|M.abscessus_ATCC_1997 EETARLRQWAAANGLTLNTVTAFAWALVLGRLTDRTDVVFGTIVSGRPKE
MLBr_02353|M.leprae_Br4923 AVGHCRPFDVRADGTVFGSGVALVALKPLQAAIDASDRIHAVILG-----
Mb2400c|M.bovis_AF2122/97 LSGVETMIGLFINTVPLRVRLDARATVGGQCAVLQRQFAMLRDHSYLGFN
Rv2379c|M.tuberculosis_H37Rv LSGVETMIGLFINTVPLRVRLDARATVGGQCAVLQRQFAMLRDHSYLGFN
MSMEG_4510|M.smegmatis_MC2_155 LSGVESMVGLFINTVPLRIRLDPAGSVGEQCLAVQREAADLRDHSYLSHT
TH_4360|M.thermoresistible__bu --------------------------------------------------
MAV_2014|M.avium_104 LTGVETMVGLFINTVPLRVRLDPAATVGEQCRAVQRDAALLREHSYLGHA
Mflv_2697|M.gilvum_PYR-GCK LAGVESMIGLFVNTVPLRVRLDPALTAGAQCRALQQDAATLRDHSYLGHA
Mvan_3844|M.vanbaalenii_PYR-1 LAGVERMVGLFINTVPLRVRLDPAAPAGEQCLALQREAAALRDHGYLSHS
MMAR_3690|M.marinum_M LPGVETMVGLFINAVPVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLS
MUL_3633|M.ulcerans_Agy99 LLGVETMVGLFINAVPVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLS
MAB_2123|M.abscessus_ATCC_1997 LPDVERMVGLFINSVPMVHHIDYSASVVEQCVQLQREAAAMRDIGYLSLS
MLBr_02353|M.leprae_Br4923 --------SAINNDGSMKMGYAAPNPAAQADVIAEAHAVAGIDSSTVSYV
Mb2400c|M.bovis_AF2122/97 EFRAIAG-IGEMFDTLLVYENFPPGEVVGTAEFVAN----GVTFRPVALE
Rv2379c|M.tuberculosis_H37Rv EFRAIAG-IGEMFDTLLVYENFPPGEVVGTAEFVAN----GVTFRPVALE
MSMEG_4510|M.smegmatis_MC2_155 EIRALGG-IGELFDTLLVYENFPPGGLVGSDEFPLGSDGDGAVLRPSALE
TH_4360|M.thermoresistible__bu --------------------------------------------------
MAV_2014|M.avium_104 QLRALGG-IGEMFDTLLVYENFPMDGLTAGGELSAG----GATFRPSALQ
Mflv_2697|M.gilvum_PYR-GCK ELRALAG-VGELFDTLLVYENFPPGAVAGAGTLEAA----GATFTPVALQ
Mvan_3844|M.vanbaalenii_PYR-1 ELRALGG-IGELFDTLLVYENFPPGGLVGQARFEAN----GATFVPSALE
MMAR_3690|M.marinum_M EIQREHG-RGPLFDSLFVFENAPIDDAIRPATTPDG-----AQFLPVEME
MUL_3633|M.ulcerans_Agy99 EIQREHG-RGPLFDSLFVFENAPIDDAIRPATTPDG-----AQFLPVEME
MAB_2123|M.abscessus_ATCC_1997 TLQRAEG-SAALFDTLFVFENAPIGDVVQEVEMADG-----ARFRPVEME
MLBr_02353|M.leprae_Br4923 ETHGTGTPLGDPIEIQGLKTAFEVSQIPRPGPCVLG------------SV
Mb2400c|M.bovis_AF2122/97 SLSHFPVTVAAHRSTGELTLLVEVLDGALGTMAPESLGRRVLAVLQRLVS
Rv2379c|M.tuberculosis_H37Rv SLSHFPVTVAAHRSTGELTLLVEVLDGALGTMAPESLGRRVLAVLQRLVS
MSMEG_4510|M.smegmatis_MC2_155 SLSHFPVTIAAHPTHGRLTVLVETLDGALGMLDPHALGRRVLTVVQRLLR
TH_4360|M.thermoresistible__bu --------------------------------------------------
MAV_2014|M.avium_104 TLSHFPIAVAAHMEGGELVVLIEVVDGALGVIPADAVGRRLLTTAERLLR
Mflv_2697|M.gilvum_PYR-GCK SLAHFPVTIAAHLTDGRLTVLVEAKDGALGQITPRALGTRLLATVSRIVE
Mvan_3844|M.vanbaalenii_PYR-1 SLSHFPVTIAAHLADDELTVFVEVIDGALGALRPGDLGRRVLHTAQRLIS
MMAR_3690|M.marinum_M SLTHYPLTVVSHLREDELLVLIEAIAEALPYLPAAEIGERMLTVLRQLPD
MUL_3633|M.ulcerans_Agy99 SLTHYPLTVVSHLREDELLVLIEAIAEALPYLPAAEIGERMLTVLRQLPD
MAB_2123|M.abscessus_ATCC_1997 SLAHYPLTVVSHMHGDSLLVLIEAIPQALPHVSGASVGERLVSVLRQLPD
MLBr_02353|M.leprae_Br4923 KSNIGHLEVAAGIAGLIKTILCLKNKAIPATLHYTSPNRELRLDQTPFVV
Mb2400c|M.bovis_AF2122/97 RWDRPLRDVDILLDGEHDPTAPGLPDVTTSA-PAVHTRFAEIAAAQPDSV
Rv2379c|M.tuberculosis_H37Rv RWDRPLRDVDILLDGEHDPTAPGLPDVTTSA-PAVHTRFAEIAAAQPDSV
MSMEG_4510|M.smegmatis_MC2_155 SWDRPVRDVAVTLDDEVATVAP--TDTAVRP-GGFHTAFTEAAAQRLGSI
TH_4360|M.thermoresistible__bu --------------------------------------------------
MAV_2014|M.avium_104 HWERPLRAVSVLFDDEAAPLRAAGPIAPPSP-KCLPARFADVVAQTPDAP
Mflv_2697|M.gilvum_PYR-GCK GWDRPLREISISPDDHPVPVPVSEAAPTPSPSTGVHTRFTETASARLGSV
Mvan_3844|M.vanbaalenii_PYR-1 CWDAPLRSVGVLLPAEHTPAPMVREPLTANS---IHDRFAGIAGDRLGSV
MMAR_3690|M.marinum_M IGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQATPDAV
MUL_3633|M.ulcerans_Agy99 IGDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQTTPDAV
MAB_2123|M.abscessus_ATCC_1997 IGGGTPDALELLTARER-AEIVVTASAADPSVVSVWDLFEREAQAHPESL
MLBr_02353|M.leprae_Br4923 QSNYGPWKWDGVRRAGVSSFGVGGTNVHVVLEEASVEASTVAASTGPQVI
Mb2400c|M.bovis_AF2122/97 AVSWADG----QLTYRELDALADRLATGLRRADVSRETPVAVALSRGPRY
Rv2379c|M.tuberculosis_H37Rv AVSWADG----QLTYRELDALADRLATGLRRADVSRETPVAVALSRGPRY
MSMEG_4510|M.smegmatis_MC2_155 ALTWDGG----ELTYRQLDEAADRVAAELRRRGVGTETPVPIRLPRGPEY
TH_4360|M.thermoresistible__bu --------------------------------------------------
MAV_2014|M.avium_104 AVSWAQG----SLTYRELDEATNRLAAQLVALGVEPETPVAIKLSRGPRY
Mflv_2697|M.gilvum_PYR-GCK ALSWDGG----ALTYRQLDEAADRLAAVLTASGVRTETPVAVRLRRGADY
Mvan_3844|M.vanbaalenii_PYR-1 ALTWEAGGDSGTLTYRQLDEAADRMAVALTAAGVGPETSVAVLLSRGPDY
MMAR_3690|M.marinum_M ALTAAAG---VRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERS
MUL_3633|M.ulcerans_Agy99 ALAAAGG---VRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERS
MAB_2123|M.abscessus_ATCC_1997 ALVADAG---TRYTYAQLRGAVSRLCAELIESGVTPETTVALALPRSADS
MLBr_02353|M.leprae_Br4923 LLSAQTA--------AALGESREALATVLEKPGAPDLSDVAYTLAGRRKH
Mb2400c|M.bovis_AF2122/97 VAAMLAVLKAGGMIVPLDPAMPGERVAEILRQTS----APVVIDEGVFAA
Rv2379c|M.tuberculosis_H37Rv VAAMLAVLKAGGMIVPLDPAMPGERVAEILRQTS----APVVIDEGVFAA
MSMEG_4510|M.smegmatis_MC2_155 VVAMLGVLKAGGLIVPLDPAMPDERVDEIIRQTHPDGRQPAIVDDAFVAA
TH_4360|M.thermoresistible__bu VIAMLAILKAGGVIVPLDPSMPGHRIAEILRQTS----APIVVDQAVSDA
MAV_2014|M.avium_104 VVAMLAVLKAGGMCVPMEPGMPAPRVNSILRQSG----ASIVLDEERIDE
Mflv_2697|M.gilvum_PYR-GCK VVAMFAVLKAGGAIVPLDPAMPADRIEVILRRAG----VTVVVDEDTVAR
Mvan_3844|M.vanbaalenii_PYR-1 VVTMLGVLKAGGVIVPLDPAMPAERISDILEQSR----ASVVVDDAFVAA
MMAR_3690|M.marinum_M IVAILGVLAAGGAYLPVDVTLPSARVESIVRQAS----PALAITEADYSQ
MUL_3633|M.ulcerans_Agy99 IVAILGVLAAGGAYLPVDVTLPSARVESIVRQAS----PALAITEADYSQ
MAB_2123|M.abscessus_ATCC_1997 IIAILAVLAAGAAYVPVDIGLPAARVESILRQSN----PTLVITVDRHRD
MLBr_02353|M.leprae_Br4923 NITMAAVVRD--REHAVTVLRAAEHDNVFVGESG----ADTGRSAAASIT
:: .:: .: . : :: .:
Mb2400c|M.bovis_AF2122/97 SVGAD--ILEDDRA---------------ITVPVDQAAYVIFTSGTTGTP
Rv2379c|M.tuberculosis_H37Rv SVGAD--ILEEDRA---------------ITVPVDQAAYVIFTSGTTGTP
MSMEG_4510|M.smegmatis_MC2_155 VRAADAELPADYRP---------------AHVHPGQGAYIVFTSGTTGKP
TH_4360|M.thermoresistible__bu VRAS----SAAWSP---------------PPVHPGQAAYTVFTSGTTGVP
MAV_2014|M.avium_104 LLEAGRSQHGGFEP---------------PDIPPAQAAYVVFTSGTTGEP
Mflv_2697|M.gilvum_PYR-GCK ATAEP---PAQYRP---------------AETLPGQAAYVVFTSGTTGEP
Mvan_3844|M.vanbaalenii_PYR-1 VPDVEP--PAGYRP---------------AEVTADRAAYIVFTSGTTGRP
MMAR_3690|M.marinum_M LVGTAVPTLALDDPAAVESISRRSAAAPTVDRRPEQSAYVIFTSGSTGEP
MUL_3633|M.ulcerans_Agy99 LVGTAVPTLALDDPAAVDSISRRSAAAPTVDRRPEQSAYVIFTSGSTGEP
MAB_2123|M.abscessus_ATCC_1997 IAGRGYQVLILDDPETAARISGRSESGHAVVVHRDQSAYLIFTSGSTGEP
MLBr_02353|M.leprae_Br4923 TLGSDRVVFLFPGQ---------------GAQHVGMAKGLYDTESVFAEH
. *.. .
Mb2400c|M.bovis_AF2122/97 KGVIGTHRALSAYADDHIERVLRPAAQRLGRPLRIAHAWSFTFDAAWQPL
Rv2379c|M.tuberculosis_H37Rv KGVIGTHRALSAYADDHIERVLRPAAQRLGRPLRIAHAWSFTFDAAWQPL
MSMEG_4510|M.smegmatis_MC2_155 KGVIGTHQALLAYAADHARNVLRPAAQRVGHPLRVAHAWSFTFDAAWQPL
TH_4360|M.thermoresistible__bu KGVVGTHDALLAYADDHARNVLRPAAARLGRPLRIAHAWSFTFDAAWQPL
MAV_2014|M.avium_104 KGVIGTHGAVGAYADDHLDRVLRPAAAALGRPLRIAHAWSFAFDAAWQPL
Mflv_2697|M.gilvum_PYR-GCK KGVIGTHRALLAYADDHIGAILRPAADRVGRPLRIAHAWSFTFDAAWQPL
Mvan_3844|M.vanbaalenii_PYR-1 KGVVGTHGAVLGYAEDHAEQVLRPAAARIGRPLRVGHAWSFTFDAAWQPL
MMAR_3690|M.marinum_M KGVVGTNAAVLSYFADHAERVYRAARARLGRPLRIAHAWSLSFDASWQPM
MUL_3633|M.ulcerans_Agy99 KGVAGTNAAVLSYFADHAERVYRAARARLGRPLRIAHAWSLSFDASWQPM
MAB_2123|M.abscessus_ATCC_1997 KGVVGTHAALMSYFADHRDRVYRPATARLGRKLRIAHAWSLSFDASWQPM
MLBr_02353|M.leprae_Br4923 FDTCSAGFREAMDDLDLHSAIFNGTAIDLER-IDRSQPALFTVEYALAKL
.. .: * : . : : : : .:. ::.: : :
Mb2400c|M.bovis_AF2122/97 VALLDGHAVHIVDDHRQRDAGALVEAIDRFGLDMIDTTPSMFAQLHNAGL
Rv2379c|M.tuberculosis_H37Rv VALLDGHAVHIVDDHRQRDAGALVEAIDRFGLDMIDTTPSMFAQLHNAGL
MSMEG_4510|M.smegmatis_MC2_155 VALLDGHANHIVGDDVQRDAEALVETIGRHAIDMIDTTPSMFTQLRAAGL
TH_4360|M.thermoresistible__bu AALFEGHAVHIIGDDVQRDAEALVDTIDRHRVDMIDITPSMFEQLRAFGL
MAV_2014|M.avium_104 VALLDGHGVHVVDEATQTDAEALVALIAEHGVDMIDTTPSMFAQLQAFGL
Mflv_2697|M.gilvum_PYR-GCK AALLDGHSVHIVDDATQRDAEALVDTIARFGVDMIDTTPSMFARLRDVGL
Mvan_3844|M.vanbaalenii_PYR-1 AALLDGHSVHLLGEESQRDAEALVYRIGRFGIDMLDTTPSMFAQLHDVGL
MMAR_3690|M.marinum_M VGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAAGL
MUL_3633|M.ulcerans_Agy99 VGLLDGHEIHLFDADEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSAAGL
MAB_2123|M.abscessus_ATCC_1997 IGLLDGHAVHLFDAEAMRDASLLVRGMAERGVDMIDTTPSMLAQLSAAGL
MLBr_02353|M.leprae_Br4923 VESFGVGAGAYIG--YSTGEYIAATLAGVFDLETAIKTVSLRARLMHESP
: .. . . :: * *: :* .
Mb2400c|M.bovis_AF2122/97 LDRAPLAVLALGGEALGAATWRMIQQNCARTAMTAFNCYGPTETTVEAVV
Rv2379c|M.tuberculosis_H37Rv LDRAPLAVLALGGEALGAATWRMIQQNCARTAMTAFNCYGPTETTVEAVV
MSMEG_4510|M.smegmatis_MC2_155 LSTVPLAVLALGGEAIDTALWQAIQAECERTWMSAHNCYGPTEATVEAVV
TH_4360|M.thermoresistible__bu LGRVPLAVLALGGEAVGIGTWRFIRDECERTGMAAYNCYGPTETTVEAVV
MAV_2014|M.avium_104 LSEAPLTVLALGGEALGNAAWARIRNACNTTTMSAYNCYGPTETTVEAVV
Mflv_2697|M.gilvum_PYR-GCK LSTVPLAVLALGGEAVDPGLWQQIRQECARTGMSAFNCYGPTETTVEAVV
Mvan_3844|M.vanbaalenii_PYR-1 LSTVPLAVLALGGEAVSPATWRLIGDECARTGMTAFNCYGPTETTVEAVV
MMAR_3690|M.marinum_M LDHN-LSVLALGGEAINTGLWDQLR---GLSQMAVYNCYGPTEMTVEAVV
MUL_3633|M.ulcerans_Agy99 LDHN-LSVLALGGEAINTGLWDQLR---GLSQMAVYNCYGPTEMTVEAVV
MAB_2123|M.abscessus_ATCC_1997 LDHE-LAVLALGGEAIETALWDRLR---SLSDTAVYNCYGPTETTVEAVV
MLBr_02353|M.leprae_Br4923 PGAMVAVALGPEDITEYLAEYSAKGVELSAVNDPGNCVVAGPKDQIRAFS
. .*. . : . : . . .: :.*.
Mb2400c|M.bovis_AF2122/97 AAVAEHARPV-IGRPTCTTRAYVMDSWLRPVPDGVAGELYLAG-----AQ
Rv2379c|M.tuberculosis_H37Rv AAVAEHARPV-IGRPTCTTRAYVMDSWLRPVPDGVAGELYLAG-----AQ
MSMEG_4510|M.smegmatis_MC2_155 AAIADHRDPC-IGKPTDPTAAYVLDSWLRPVPAGVAGELYLAG-----GQ
TH_4360|M.thermoresistible__bu GRFAAHEQPV-IGLPTRHTRAYVLDAWLRPVPDGVAGELYLAG-----AQ
MAV_2014|M.avium_104 AAIAEHAEPS-IGRPTRHTRGYVLDSELRPVPCGATGELYLGG-----AQ
Mflv_2697|M.gilvum_PYR-GCK AEIGAHERPT-IGRPTAPTRAYVLDSWLRPVPSGAAGELYLAG-----GQ
Mvan_3844|M.vanbaalenii_PYR-1 APIDGYQRPS-IGQPTRTMRTYVLDAWLRPVPDGVAGELYLSG-----RQ
MMAR_3690|M.marinum_M AAVKDYRKPT-IGTANAGTFGYVFDSALRMVPDGVVGELYLSG-----AQ
MUL_3633|M.ulcerans_Agy99 AAVKDYRKPT-IGTANAGTFGYVFDSALRMVPDGVVGELYLSG-----AQ
MAB_2123|M.abscessus_ATCC_1997 AAVKEYPAPT-IGTPNQGMVGYVLDSRLRPVPDGAVGELYLAG-----AQ
MLBr_02353|M.leprae_Br4923 QRLDEVGIPVRRVRATHAFHTSSMEPMLREFSEFLSRQQLRVPNTPLLSN
. * .. ::. ** .. : :
Mb2400c|M.bovis_AF2122/97 LTRGYLGRPAETAARFVAEPNGRGSRMYRTGDVVRRLPDGGLEFLGRSD-
Rv2379c|M.tuberculosis_H37Rv LTRGYLGRPAETAARFVAEPNGRGSRMYRTGDVVRRLPDGGLEFLGRSD-
MSMEG_4510|M.smegmatis_MC2_155 LTRGYVGRPGETAARFVADPFTLGARMYRTGDVVRRTPDGALQFLGRSD-
TH_4360|M.thermoresistible__bu LTRGYLGRAGETATRFVPDPFDPGRRMYRTGDVVRRTADGALQYLGRSD-
MAV_2014|M.avium_104 LARGYLGRAGETASRFVADPFAASERMYRTGDLVRRLPDGSLQYVGRAD-
Mflv_2697|M.gilvum_PYR-GCK LTRGYLGRPGETAARFVPDPFVPGARMYRTGDVVRRAVDGTLAFLGRSD-
Mvan_3844|M.vanbaalenii_PYR-1 LTRGYLGRAAETAGRFVADPFTPGQRMYRTGDVVRRGADGGLQFLGRAD-
MMAR_3690|M.marinum_M LARGYVGRPGMTAARFVADPLRPGQRMYRTGDLVRRLSHGGYAYVGRAD-
MUL_3633|M.ulcerans_Agy99 LARGYVGRPGMTAARFVADPLRPGQRMYRTGDLVRRLSHGGYAYVGRAD-
MAB_2123|M.abscessus_ATCC_1997 LARGYAGKPAVTAAAFVADPRRAGQRMYRTGDLVRRLPHGGFAYLGRAD-
MLBr_02353|M.leprae_Br4923 LTGTWMSEQQVTDPENWTRQISSTIRFADELDVVLSQSGRVLVEVGPGGS
*: : .. * . *: *:* :* ..
Mb2400c|M.bovis_AF2122/97 -DQVKIRGFRVEPGEIAAVLNGHHAVHGCHVTARGHASGPRLTAYVAGGP
Rv2379c|M.tuberculosis_H37Rv -DQVKIRGFRVEPGEIAAVLNGHHAVHGCHVTARGHASGPRLTAYVAGGP
MSMEG_4510|M.smegmatis_MC2_155 -DQVKIRGFRVEPGEVAAALHRHPQVRHAHVALRRHRSGPRLVAYVVTDA
TH_4360|M.thermoresistible__bu -DQVKIRGFRVEPGEVAAVLQTHPAVRAAHVAVRRHRSGPRLVGYVATGG
MAV_2014|M.avium_104 -AQVKIRGHRVEPGEIAAALESHPAVRHAGVLVRHRDGAPRLTGYVATHE
Mflv_2697|M.gilvum_PYR-GCK -TQVKIRGFRVEPGEVAAVLRTHPAVGQAYVAVRPHRDGHRLTAYVTGEP
Mvan_3844|M.vanbaalenii_PYR-1 -NQVKIRGFRVEPGEIAAVLSGHPAVTDAHVVVDRVGTQTRLIAYVAAAT
MMAR_3690|M.marinum_M -TQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQDRTSLVGFVVWQD
MUL_3633|M.ulcerans_Agy99 -TQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQDRTSLVGFVVWQD
MAB_2123|M.abscessus_ATCC_1997 -SQVKIRGYRVEVGEIESALRLQPDIQTAAVTVVRRAGGASLVGFVVCEK
MLBr_02353|M.leprae_Br4923 LTGSAMRHPRWSSGHRAVRLMRHPLQNVDDHDTFLRALGELWSAGIEVDW
:* * . *. * : . :
Mb2400c|M.bovis_AF2122/97 QPPPVA---ELRAMLLERLP--RYLVPHHIVVLDELPLTPHGKIDENALA
Rv2379c|M.tuberculosis_H37Rv QPPPVA---ELRAMLLERLP--RYLVPHHIVVLDELPLTPHGKIDENALA
MSMEG_4510|M.smegmatis_MC2_155 SLADAAG--ELRRMLAATLP--RYLVPHHILLVDEIPLTTNGKVDDARLA
TH_4360|M.thermoresistible__bu AEVDVD---ELRRMLVARLP--RYLVPHRVTVLDQLPLTPHGKIDDAALA
MAV_2014|M.avium_104 AAPDTPSPAELRGMLSARLP--RYMVPQRIIMVDEIPLTPNGKLDETALA
Mflv_2697|M.gilvum_PYR-GCK QLR------ELRAWLGRRLP--RYLMPNAIVAVDRIPLTAHGKIDEPALV
Mvan_3844|M.vanbaalenii_PYR-1 PPAVAD----LRELMAKRLP--RYMVPQRVVVLDELPLTSHGKIDEAALA
MMAR_3690|M.marinum_M NMHEDLI--KLRAGLTERLP--SYMVPARIVTLPRLPVNANGKLDGHALD
MUL_3633|M.ulcerans_Agy99 NMHEDLI--KLRAGLTERLP--SYMVPARIVTLPRLPVNANGKLDGHALD
MAB_2123|M.abscessus_ATCC_1997 DTFDSAR--TMMR-LADRLP--SYMMPSRLVPLPQLPVTVNGKLDGGALE
MLBr_02353|M.leprae_Br4923 APQRSVMP-HLVSLPGYPFARQRHWVEPRYTIWAQIPGASSGSPVDSSVD
: :. : : .:* *. :
Mb2400c|M.bovis_AF2122/97 AIN------VTEGPATPPQTPTELVLAEAFADVMETSNVDVTAGFLQMGL
Rv2379c|M.tuberculosis_H37Rv AIN------VTEGPATPPQTPTELVLAEAFADVMETSNVDVTAGFLQMGL
MSMEG_4510|M.smegmatis_MC2_155 ALDSG----RQSGGFQGPATDTERVVAEVLAEVLDTRAVDVTAEFLDLGL
TH_4360|M.thermoresistible__bu AHDDA----TGSP-VAEPETPTEKALVEAVVDLLGPTPVDVDAELLSLGV
MAV_2014|M.avium_104 AVDNA----EAVDGAATPQTGTESALAELIAELLGQPRVDVTADFLALGL
Mflv_2697|M.gilvum_PYR-GCK ALEP-----AADGAATRPQTPTEVELAAVLAEVLGVGEIDVTADFLELGL
Mvan_3844|M.vanbaalenii_PYR-1 GIA------VEDAPSAAPETPTETALVELMAEVLGDDGIDVEADFLEMGL
MMAR_3690|M.marinum_M RLAEDALTSVSGGTAVSASTDTERVLCELFEEQLN-AVPHIDDDLFLFGM
MUL_3633|M.ulcerans_Agy99 RLAEDALTSVSGGTAVSASTDTERVLCELFEEQLN-AVPHIDDDLFLFGM
MAB_2123|M.abscessus_ATCC_1997 RLAREALSGGAVGEQAQPATATECVLCECCAELFDGTAPGIDEDFFSLGV
MLBr_02353|M.leprae_Br4923 SAT--------VEGVRGGESQTEATLQRIWSQCLGVSSVDRNANFFDLGG
: ** : : : :: :*
Mb2400c|M.bovis_AF2122/97 DSIVALSVVQAARRRGIALRARLMVECDTIRELAAAIDSDAAWQAPAN--
Rv2379c|M.tuberculosis_H37Rv DSIVALSVVQAARRRGIALRARLMVECDTIRELAAAIDSDAAWQAPAN--
MSMEG_4510|M.smegmatis_MC2_155 DSIVALTVVQAVRRRGLALRARLMLECANVRELAAAIDADAHHAAVDHTP
TH_4360|M.thermoresistible__bu DSIVALSVVQAARRRGLALRARLMLECGSIRELAAAIDAEANAAPDTESA
MAV_2014|M.avium_104 DSIMALSVVQAARARGIALRARLVLDCTSIRELAEAIDAESTPAAGEVD-
Mflv_2697|M.gilvum_PYR-GCK DSIVALSVVQTARRRGVVMRAKLMLDCATVRELAAAIDDAGSGPPSAD--
Mvan_3844|M.vanbaalenii_PYR-1 DSIVALTLVQAARRRGLEMRARLMLECNTIRELATAIDSGAHDHAPAAVT
MMAR_3690|M.marinum_M DSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPAD-
MUL_3633|M.ulcerans_Agy99 DSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPAD-
MAB_2123|M.abscessus_ATCC_1997 DSIVAISLVNKARKRDLVITPRMVLAAPTIRQLAALVDTRGHVDSLAGE-
MLBr_02353|M.leprae_Br4923 DSLMAISISMAAANEGMTITPQDMYEHPTLASLTAAVDASFASSGLAKPP
**::*::: . ..: : .: : .: .* :*
Mb2400c|M.bovis_AF2122/97 --DAGEPIPVLPNTHWLYEYGDPRRLAQTEVIRLPDRITRERLDAVLAAV
Rv2379c|M.tuberculosis_H37Rv --DAGEPIPVLPNTHWLYEYGDPRRLAQTEVIRLPDRITRERLDAVLAAV
MSMEG_4510|M.smegmatis_MC2_155 EDSG--PIPLLPNGSWLYQYGEPRRLAQTEAFRLPEGTTAAQLRTLLRTV
TH_4360|M.thermoresistible__bu DAGAGEPIPVLPAVHWLYQHGDPRRLAQTEAIRLPDGITGADLRTLLTTV
MAV_2014|M.avium_104 --DGTGPMPLLPNGRWLYEHGQPRRLAQTEAIRVPQTLRRDQLETALAGI
Mflv_2697|M.gilvum_PYR-GCK --EGSGPIALLPNAHWLYEFGDPRRLASTEALRLPRGITGPQIRALLQSV
Mvan_3844|M.vanbaalenii_PYR-1 -DDRFGEVMPAPIMSWMYECGNYRRFTQNVLVSLPADITDSRLEQILQAL
MMAR_3690|M.marinum_M --ADYGAVRPLPMVSWLYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLL
MUL_3633|M.ulcerans_Agy99 --ADYGAVLPLPMVSWLYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLL
MAB_2123|M.abscessus_ATCC_1997 --ADYGEVPPLPVVSWMYESEIYRRLSLSVLVRLPAGIDRPGIERMLQLL
MLBr_02353|M.leprae_Br4923 EAAAHPAVPPNIAYFLERGLCDTGRWRVPLILRLDPKIGSDDIRAVLTAV
: * . : : * :
Mb2400c|M.bovis_AF2122/97 VDGHEVLRCRFDR--DAMALVAQPK---TDILSEVWVS------GELVTA
Rv2379c|M.tuberculosis_H37Rv VDGHEVLRCRFDR--DAMALVAQPK---TDILSEVWVS------GELVTA
MSMEG_4510|M.smegmatis_MC2_155 VDGHEVLRTRLDR--VTRTLVPHGP---RDVLTEAVGV------GTLADA
TH_4360|M.thermoresistible__bu VASHEVLRTRLDR--TTMTLVPQHDGDIGDRLREVTVR------GDLTAA
MAV_2014|M.avium_104 IDGHEVLRSRVDR--ATMTLVPGPAPDIGKELEEVAVV------GDLRAA
Mflv_2697|M.gilvum_PYR-GCK VDAHPVLRTRLDR--AAMTLVDGGF---DLPLTEIEVG------DEGSAA
Mvan_3844|M.vanbaalenii_PYR-1 LDRHDMLRAILD---ERGRLVTRPPGAVRVADVLRVVD------AAAHTV
MMAR_3690|M.marinum_M LDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASA
MUL_3633|M.ulcerans_Agy99 LDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRIRLPEGSDDELASA
MAB_2123|M.abscessus_ATCC_1997 LDGFTMLRSTLVDTPDGARVVTREPGVVRGESVLSRVELPTG--ESAHAA
MLBr_02353|M.leprae_Br4923 VNHHDVLRLSLVDNDGMWEQHIAATGEFTRLLTQTLPDG----VAAGSAE
: . ** .
Mb2400c|M.bovis_AF2122/97 VAEQTLGVLASLDPQAGRLLSAVWLR---EPDGPG-VLVLTAHVLAMDPA
Rv2379c|M.tuberculosis_H37Rv VAEQTLGALASLDPQAGRLLSAVWLR---EPDGPG-VLVLTAHVLAMDPA
MSMEG_4510|M.smegmatis_MC2_155 VAEQAALSVDRIDPQQGSMLDAVWLR---HPDAPGGVFILTAHVLALDPA
TH_4360|M.thermoresistible__bu VAEQVDLSVRTLDPEGGRLWSAVWLR---PEQGPG-VLVWTAHVIAMDPA
MAV_2014|M.avium_104 VADRAARAIDRLDPERGVLLGAVWLR---PADGDG-VLLLTAHVIALDPA
Mflv_2697|M.gilvum_PYR-GCK VARHAAAALEHLDPQRGPLWGAVWLRGSDDADSTSSVLLLTAHVLAMDPV
Mvan_3844|M.vanbaalenii_PYR-1 LAAEVVAALDRIDPTSGAMVQAVWFR-----HGPP-VLALCVHHLSTDVV
MMAR_3690|M.marinum_M VAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVV
MUL_3633|M.ulcerans_Agy99 VAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANMLLLTAHHLAVDVV
MAB_2123|M.abscessus_ATCC_1997 ITNAARQAFDSLDPRSGAMMRAVWLAS----RDSGDVLLLTVHHLAMDVV
MLBr_02353|M.leprae_Br4923 ERAVVSSILAELIASQSDLNEPLTAVQITTAHGGPHYLGLAVHQMVIDDA
. : . . : .: : .* : * .
Mb2400c|M.bovis_AF2122/97 SWRIVLGELDAGLHALAAGRAPSPARENTSYRQWSRLLAQRAKALDS---
Rv2379c|M.tuberculosis_H37Rv SWRIVLGELDAGLHALAAGRAPSPARENTSYRQWSRLLAQRAKALDS---
MSMEG_4510|M.smegmatis_MC2_155 SWRIVVGELETAWHALASGREPTPVREHTSLRRWSRMLSERALKLDT---
TH_4360|M.thermoresistible__bu SWRVVLGDLDAGWHALSAGRPS----------------------------
MAV_2014|M.avium_104 SWRVVLGELGAALTAAATGHSPAAVREHTSYRRWAHALTARAHRLDT---
Mflv_2697|M.gilvum_PYR-GCK SWQIVIGELDAGWHALAGGRAPAALGEHTGYRQWSNLLRERAESSDG---
Mvan_3844|M.vanbaalenii_PYR-1 SWYLILGALAQIDATLAAGHAPDPAAEYTTYREWTRRLYQRSRTEAVERR
MMAR_3690|M.marinum_M SWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQ
MUL_3633|M.ulcerans_Agy99 SWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQ
MAB_2123|M.abscessus_ATCC_1997 SWHIVLGYLADAWIAVRSGTAPKAPMEFTSYRQWSQLMHQRASSHDVLRQ
MLBr_02353|M.leprae_Br4923 SRQILGTDIITAFGQRLAGEEITLEPVTTGWREWSLRCAALATHPAALDT
* :: : *
Mb2400c|M.bovis_AF2122/97 VDFWVAELEGADPPLGARRVAPQTDR---VGELAITMSISDADLTARLLS
Rv2379c|M.tuberculosis_H37Rv VDFWVAELEGADPPLGARRVAPQTDR---VGELAITMSISDADLTARLLS
MSMEG_4510|M.smegmatis_MC2_155 VDFWHRQFDGADPDIGARRVDPATDR---MRDIAVEMTFADADLTARLLT
TH_4360|M.thermoresistible__bu --------------------------------------------------
MAV_2014|M.avium_104 VGFWASELDGDDPDLGARRVDPARDR---ARDLLVRNVATDADLTRRLLE
Mflv_2697|M.gilvum_PYR-GCK LQFWLDQLGGPDPALGARRVRPDTDR---AGDVRVTVTVTGADVTARLLA
Mvan_3844|M.vanbaalenii_PYR-1 RGFWVEQLAGSDPLLGRRLPDPRHDT---WSTLQSTDVVTDAGATRAILD
MMAR_3690|M.marinum_M RDYWAALVREPDPALGLRYPDPTRDT---WSTLQLTRAAIPVDVTERVLG
MUL_3633|M.ulcerans_Agy99 RDYWAALVREPDPELGLRYPDPTRDT---WSTLQLTRAAIPVDVTERVLG
MAB_2123|M.abscessus_ATCC_1997 RDYWAEQVSGADPELGSRHADPSRDT---WGTLQTTAVPTPVAVTTRLLA
MLBr_02353|M.leprae_Br4923 RSFWIENANKVNLWLADVSLNTDVIQPPGADDLIRMPCTLSVEQTSELDD
Mb2400c|M.bovis_AF2122/97 ----TGRSMTDLLATAAARMVTAWRRQRGQQTPA-PLLALETHGRADVHV
Rv2379c|M.tuberculosis_H37Rv ----TGRSMTDLLATAAARMVTAWRRQRGQQTPA-PLLALETHGRADVHV
MSMEG_4510|M.smegmatis_MC2_155 ----GGVPVTEVLAAATARTVTAWRRERGQPTPA-PLLALETHGRADAVV
TH_4360|M.thermoresistible__bu --------------------------------------------------
MAV_2014|M.avium_104 ----SGLPLPTLLVAATAATVTRWRRQRGQSTPP-PLLALETHGRADSLV
Mflv_2697|M.gilvum_PYR-GCK ----GPHPVLDVLVAALGRTITEWRGRRNQPTPP-PLVALETHGRA-ALA
Mvan_3844|M.vanbaalenii_PYR-1 RLDGASLEVRDFLLTALTLTLASWRIERGQPAHHGALVALEGHGREDALV
MMAR_3690|M.marinum_M AVR-RDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVL
MUL_3633|M.ulcerans_Agy99 AVR-RDQGVRELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVL
MAB_2123|M.abscessus_ATCC_1997 SLN-KPEGVYSFLLSALAVTVASWRKLRGQDSTAGTLVSLEGHGRADGEL
MLBr_02353|M.leprae_Br4923 ARRRFRRSIQAIVLAALGRTIAQTVGDG--------VVAVELEGEGRSVL
Mb2400c|M.bovis_AF2122/97 DK-------TADTSDTVGLLSAIYPLRIHCDGA-----------------
Rv2379c|M.tuberculosis_H37Rv DK-------TADTSDTVGLLSAIYPLRIHCDGA-----------------
MSMEG_4510|M.smegmatis_MC2_155 SADLGEDPHQVDTGDTAGLLSMIYPLRVTAGDA-----------------
TH_4360|M.thermoresistible__bu --------------------------------------------------
MAV_2014|M.avium_104 DG---PGAHTIDTGDTVGLLSSIYPIRVDAADP-----------------
Mflv_2697|M.gilvum_PYR-GCK EADTADTADTADTSDTVGLLSAIYPLRLHEDSP-----------------
Mvan_3844|M.vanbaalenii_PYR-1 GG-------GVDTSATVGWFTSVYPVRLGAGEAAIDVDTAARNPAAARSL
MMAR_3690|M.marinum_M DT---------DTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDL
MUL_3633|M.ulcerans_Agy99 DT---------DTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDL
MAB_2123|M.abscessus_ATCC_1997 DT---------DTSGTVGWFTTVYPVRVAAGEAAIDVDRMENDVNAARQL
MLBr_02353|M.leprae_Br4923 RP-------DVDVRRTIGWFTNYYPIPLVCVKGQ-----------GALAQ
Mb2400c|M.bovis_AF2122/97 -TDFAR----IPGSGIDYGLLRYLRADTAERLRAHREPQLLLNYLGSLHV
Rv2379c|M.tuberculosis_H37Rv -TDFAR----IPGSGIDYGLLRYLRADTAERLRAHREPQLLLNYLGSLHV
MSMEG_4510|M.smegmatis_MC2_155 -RGVAELVAAIPGDPIDYGLLRHLREDTAESLGVHRDPQLLLNYLGRIEL
TH_4360|M.thermoresistible__bu --------------------------------------------------
MAV_2014|M.avium_104 -RRVADKLAAIPGDGLDYGLLRYLRDDTAERLAALPSPQLLLNYLGAAHT
Mflv_2697|M.gilvum_PYR-GCK -GATTELIAGVPAGGIDYGLLRYLRPDTSEVLKAHPEPQILLNYLGRTDL
Mvan_3844|M.vanbaalenii_PYR-1 LRAVIQQLAEVPDKGLDYGLLRYTRRD--ETLRALPEPQVEFNYIGRYDL
MMAR_3690|M.marinum_M VHSVVSHLEAIPNDGLDYGLLRY--VDGVAELVDAVDPQIQFSYLGRLDL
MUL_3633|M.ulcerans_Agy99 VHSVVSHLEAIPNDGLDYGLLRY--VDGVAELVDAVDPQIQFSYLGRLDL
MAB_2123|M.abscessus_ATCC_1997 LAGVARHIDEIPYQGLDYGLLRY--VRGCEELSSARDPQIQFNYVGRMDI
MLBr_02353|M.leprae_Br4923 LDAVHNTLKSIPHYGIGYGLLRYMYAPTGRVFSAQRTPDIHFRYVGVVPE
Mb2400c|M.bovis_AF2122/97 GVG------DLAVDRALLADVGQLPEPEQPVRHELTVLAALLGPADAPVL
Rv2379c|M.tuberculosis_H37Rv GVG------DLAVDRALLADVGQLPEPEQPVRHELTVLAALLGPADAPVL
MSMEG_4510|M.smegmatis_MC2_155 DSAD----HALLQDRSLLSGVTPIPEPDVAVRHELTIMAAVIDRDGSAVL
TH_4360|M.thermoresistible__bu --------------------------------------------------
MAV_2014|M.avium_104 DGG-----TGLTLERELLAGLSPIPEPDLAVRHELTIAAMVLTYGGQRVL
Mflv_2697|M.gilvum_PYR-GCK VPS-----GAIVADRLLLSGLSTVPEPNAAVRHELTVVAAVVAHGDEPAL
Mvan_3844|M.vanbaalenii_PYR-1 SADQTSQAWSLITDETLNAHMPAAAEPDLPLRYTFDVISVISGGADGPQL
MMAR_3690|M.marinum_M GGVA-DQPWSLLTG-PYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQL
MUL_3633|M.ulcerans_Agy99 GGVA-DQPWSLLTG-PYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQL
MAB_2123|M.abscessus_ATCC_1997 SGID-DQPWSLITD-ARSLAVPPDSEPDLPLRFAINIGSAVMTTPEGPQL
MLBr_02353|M.leprae_Br4923 PPS------VDATVQFDSDMTIPVQEPVPGMGHAIELRTYRFGGSLHLDW
Mb2400c|M.bovis_AF2122/97 ATRWRTLPDILSADDVATLQSLWQGALAEITA------------------
Rv2379c|M.tuberculosis_H37Rv ATRWRTLPDILSADDVATLQSLWQGALAEITA------------------
MSMEG_4510|M.smegmatis_MC2_155 GAQWRTLPDILSAAEVGTLQTMWLDALREVVE------------------
TH_4360|M.thermoresistible__bu --------------------------------------------------
MAV_2014|M.avium_104 AAQWRTLPDILTDTDITALQELWVDSLREMVT------------------
Mflv_2697|M.gilvum_PYR-GCK VAQWRVLPEILSDTDVEEMQTIWQDTLREVL-------------------
Mvan_3844|M.vanbaalenii_PYR-1 RTSWRWSTALSTSTEVDRLTALWQQAVTVLGEAL----------------
MMAR_3690|M.marinum_M IGNWRWSDAVFERSDIDHLTGLWQRGIAALAAGLD---------------
MUL_3633|M.ulcerans_Agy99 IGNWRWSDAVFERSDIDHLTGLWQRGIAALAAGLD---------------
MAB_2123|M.abscessus_ATCC_1997 LTNWQLSSALFTPADASRLAQLWQRSVAALAGALDG--------------
MLBr_02353|M.leprae_Br4923 WYDIRRIPQVTAEALAQSFPVTLSKLIQEGIATQKDAHDESEMAGAPQAG
Mb2400c|M.bovis_AF2122/97 -----------
Rv2379c|M.tuberculosis_H37Rv -----------
MSMEG_4510|M.smegmatis_MC2_155 -----------
TH_4360|M.thermoresistible__bu -----------
MAV_2014|M.avium_104 -----------
Mflv_2697|M.gilvum_PYR-GCK -----------
Mvan_3844|M.vanbaalenii_PYR-1 -----------
MMAR_3690|M.marinum_M -----------
MUL_3633|M.ulcerans_Agy99 -----------
MAB_2123|M.abscessus_ATCC_1997 -----------
MLBr_02353|M.leprae_Br4923 VLVDLSTLDAG