For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VTGTEQQPQIEDVLALSPLQEGFFALSQLADESVDLYSMQFVADIDGGLDVDLLHRSAQALLTRHPNLRA AFWDRGLPKPVQIVPTHADIPWEEREAQPTEFDEIALRERLRPFNLGKGPAIRLVLLTVPGESRHRMIVT SHHILMDGWAIAIFFSELLAVYQAGGSLAGLPAVRPYRDYIAWLNAQDTTEATARWTRYLGTVSGPLMLA DGAVAAHDNVPEKSQFLLAPEETARLRQWAAANGLTLNTVTAFAWALVLGRLTDRTDVVFGTIVSGRPKE LPDVERMVGLFINSVPMVHHIDYSASVVEQCVQLQREAAAMRDIGYLSLSTLQRAEGSAALFDTLFVFEN APIGDVVQEVEMADGARFRPVEMESLAHYPLTVVSHMHGDSLLVLIEAIPQALPHVSGASVGERLVSVLR QLPDIGGGTPDALELLTARERAEIVVTASAADPSVVSVWDLFEREAQAHPESLALVADAGTRYTYAQLRG AVSRLCAELIESGVTPETTVALALPRSADSIIAILAVLAAGAAYVPVDIGLPAARVESILRQSNPTLVIT VDRHRDIAGRGYQVLILDDPETAARISGRSESGHAVVVHRDQSAYLIFTSGSTGEPKGVVGTHAALMSYF ADHRDRVYRPATARLGRKLRIAHAWSLSFDASWQPMIGLLDGHAVHLFDAEAMRDASLLVRGMAERGVDM IDTTPSMLAQLSAAGLLDHELAVLALGGEAIETALWDRLRSLSDTAVYNCYGPTETTVEAVVAAVKEYPA PTIGTPNQGMVGYVLDSRLRPVPDGAVGELYLAGAQLARGYAGKPAVTAAAFVADPRRAGQRMYRTGDLV RRLPHGGFAYLGRADSQVKIRGYRVEVGEIESALRLQPDIQTAAVTVVRRAGGASLVGFVVCEKDTFDSA RTMMRLADRLPSYMMPSRLVPLPQLPVTVNGKLDGGALERLAREALSGGAVGEQAQPATATECVLCECCA ELFDGTAPGIDEDFFSLGVDSIVAISLVNKARKRDLVITPRMVLAAPTIRQLAALVDTRGHVDSLAGEAD YGEVPPLPVVSWMYESEIYRRLSLSVLVRLPAGIDRPGIERMLQLLLDGFTMLRSTLVDTPDGARVVTRE PGVVRGESVLSRVELPTGESAHAAITNAARQAFDSLDPRSGAMMRAVWLASRDSGDVLLLTVHHLAMDVV SWHIVLGYLADAWIAVRSGTAPKAPMEFTSYRQWSQLMHQRASSHDVLRQRDYWAEQVSGADPELGSRHA DPSRDTWGTLQTTAVPTPVAVTTRLLASLNKPEGVYSFLLSALAVTVASWRKLRGQDSTAGTLVSLEGHG RADGELDTDTSGTVGWFTTVYPVRVAAGEAAIDVDRMENDVNAARQLLAGVARHIDEIPYQGLDYGLLRY VRGCEELSSARDPQIQFNYVGRMDISGIDDQPWSLITDARSLAVPPDSEPDLPLRFAINIGSAVMTTPEG PQLLTNWQLSSALFTPADASRLAQLWQRSVAALAGALDG
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_2123 | - | - | 100% (1509) | putative peptide synthetase MbtF |
M. abscessus ATCC 19977 | MAB_4099c | - | 0.0 | 32.50% (1557) | non-ribosomal peptide synthetase |
M. abscessus ATCC 19977 | MAB_4691c | - | e-151 | 33.07% (1409) | non-ribosomal peptide synthetase PstA |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2400c | mbtF | 0.0 | 41.73% (1524) | peptide synthetase MBTF (peptide synthase) |
M. gilvum PYR-GCK | Mflv_2697 | - | 0.0 | 41.79% (1517) | amino acid adenylation domain-containing protein |
M. tuberculosis H37Rv | Rv2379c | mbtF | 0.0 | 41.80% (1524) | peptide synthetase MBTF (peptide synthase) |
M. leprae Br4923 | MLBr_02353 | - | 7e-22 | 24.85% (499) | polyketide synthase |
M. marinum M | MMAR_3690 | mbtF | 0.0 | 60.94% (1513) | non-ribosomal peptide synthetase MbtF |
M. avium 104 | MAV_2014 | - | 0.0 | 42.78% (1531) | putative sulfotransferase |
M. smegmatis MC2 155 | MSMEG_4510 | - | 0.0 | 41.04% (1535) | peptide synthetase mbtf |
M. thermoresistible (build 8) | TH_3730 | - | 1e-170 | 33.77% (1297) | PUTATIVE linear gramicidin synthetase subunit D |
M. ulcerans Agy99 | MUL_3633 | mbtF | 0.0 | 60.61% (1513) | non-ribosomal peptide synthetase MbtF |
M. vanbaalenii PYR-1 | Mvan_3844 | - | 0.0 | 45.25% (1525) | amino acid adenylation domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_3690|M.marinum_M -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MAB_2123|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2400c|M.bovis_AF2122/97 -------------------------------------------------- Rv2379c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4510|M.smegmatis_MC2_155 -------------------------------------------------- MAV_2014|M.avium_104 -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3730|M.thermoresistible__bu VTTAELGARLHRSGVPVIHIDDPAAPGQAGATTGPAPAPDDIAYIIYTSG MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_3690|M.marinum_M -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MAB_2123|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2400c|M.bovis_AF2122/97 -------------------------------------------------- Rv2379c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4510|M.smegmatis_MC2_155 -------------------------------------------------- MAV_2014|M.avium_104 -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3730|M.thermoresistible__bu TTGVPKGVAVTHRNVAALLSALDAELASGQVWTQCHSLAFDFSVWEIWGP MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_3690|M.marinum_M -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MAB_2123|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2400c|M.bovis_AF2122/97 -------------------------------------------------- Rv2379c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4510|M.smegmatis_MC2_155 -------------------------------------------------- MAV_2014|M.avium_104 -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3730|M.thermoresistible__bu LLYGGRVVIVPDPVVRSPEDLHALLAAEQVGMLSQTPSAFYALQTADSLQ MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_3690|M.marinum_M -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MAB_2123|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2400c|M.bovis_AF2122/97 -------------------------------------------------- Rv2379c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4510|M.smegmatis_MC2_155 -------------------------------------------------- MAV_2014|M.avium_104 -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3730|M.thermoresistible__bu PEQARQLQLQTVVFGGEALEPQRLSAWMRNHPERPRLINMYGITETTVHA MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_3690|M.marinum_M -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MAB_2123|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2400c|M.bovis_AF2122/97 -------------------------------------------------- Rv2379c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4510|M.smegmatis_MC2_155 -------------------------------------------------- MAV_2014|M.avium_104 -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3730|M.thermoresistible__bu SFREIGAADLDDNTSPIGRPLPHLAFFVLDGWLRPVPPGVVGELYVAGAG MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_3690|M.marinum_M -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MAB_2123|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2400c|M.bovis_AF2122/97 -------------------------------------------------- Rv2379c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4510|M.smegmatis_MC2_155 -------------------------------------------------- MAV_2014|M.avium_104 -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3730|M.thermoresistible__bu LATGYVSRSDLTSTRFVACPFGPPGTRMYRTGDLVRWDTGGELHYIGRAD MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_3690|M.marinum_M -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MAB_2123|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2400c|M.bovis_AF2122/97 -------------------------------------------------- Rv2379c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4510|M.smegmatis_MC2_155 -------------------------------------------------- MAV_2014|M.avium_104 -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3730|M.thermoresistible__bu EQVKIRGYRIELGEIQAALARLDGVDQAAVIAREDRPGDKRLVGYITGTA MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_3690|M.marinum_M -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MAB_2123|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2400c|M.bovis_AF2122/97 -------------------------------------------------- Rv2379c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4510|M.smegmatis_MC2_155 -------------------------------------------------- MAV_2014|M.avium_104 -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3730|M.thermoresistible__bu DPVQARAQLADRLPPYMVPAAIVVLESIPLTSNNKLDVRALPAPEYRATG MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_3690|M.marinum_M -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MAB_2123|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2400c|M.bovis_AF2122/97 -------------------------------------------------- Rv2379c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4510|M.smegmatis_MC2_155 -------------------------------------------------- MAV_2014|M.avium_104 -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3730|M.thermoresistible__bu AEYRAPGTPLEGLLAGIFAEVLGVERVGVDDSFFDLGGDSILSMQVVARA MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_3690|M.marinum_M -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MAB_2123|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2400c|M.bovis_AF2122/97 -------------------------------------------------- Rv2379c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4510|M.smegmatis_MC2_155 -------------------------------------------------- MAV_2014|M.avium_104 -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3730|M.thermoresistible__bu RAAGVQCRPRDIFVEQTVARLASVVKVSGGEPETVDDGTGAVVATPIMRW MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_3690|M.marinum_M -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MAB_2123|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2400c|M.bovis_AF2122/97 -------------------------------------------------- Rv2379c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4510|M.smegmatis_MC2_155 -------------------------------------------------- MAV_2014|M.avium_104 -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3730|M.thermoresistible__bu LRGVDGPTDQFNQTVVLQAPPGTDTAAAEADVVAVLQALIDRHPTLRMRA MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_3690|M.marinum_M -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MAB_2123|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2400c|M.bovis_AF2122/97 -------------------------------------------------- Rv2379c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4510|M.smegmatis_MC2_155 -------------------------------------------------- MAV_2014|M.avium_104 -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3730|M.thermoresistible__bu EGMTAGDGTDDWSLFIPEPGATSAREVMHTVDTLTDEVLIAARSRLNPAA MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_3690|M.marinum_M -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MAB_2123|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2400c|M.bovis_AF2122/97 -------------------------------------------------- Rv2379c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4510|M.smegmatis_MC2_155 -------------------------------------------------- MAV_2014|M.avium_104 -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3730|M.thermoresistible__bu GVMLSAVWARGSGQLVLMIHHLAVDGVSWRILVEDLNIAWAQHRTGQPID MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_3690|M.marinum_M -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MAB_2123|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2400c|M.bovis_AF2122/97 -------------------------------------------------- Rv2379c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4510|M.smegmatis_MC2_155 -------------------------------------------------- MAV_2014|M.avium_104 -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3730|M.thermoresistible__bu LPANGTSFARWSALLADHARAPEVVEHVEAWQRVIAAPSALPAIRPERDT MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_3690|M.marinum_M -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MAB_2123|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2400c|M.bovis_AF2122/97 -------------------------------------------------- Rv2379c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4510|M.smegmatis_MC2_155 -------------------------------------------------- MAV_2014|M.avium_104 -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3730|M.thermoresistible__bu YATAGQLSVSLDADTTRQLLGAVPAAFHAGVQDILLIAFGLAWAEFLGAC MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_3690|M.marinum_M -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MAB_2123|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2400c|M.bovis_AF2122/97 -------------------------------------------------- Rv2379c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4510|M.smegmatis_MC2_155 -------------------------------------------------- MAV_2014|M.avium_104 -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3730|M.thermoresistible__bu DSPIGIDVEGHGRAEELAAGVDLSRTVGWFTTKYPVALTIPKLSWEQVRT MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_3690|M.marinum_M -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MAB_2123|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2400c|M.bovis_AF2122/97 -------------------------------------------------- Rv2379c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4510|M.smegmatis_MC2_155 -------------------------------------------------- MAV_2014|M.avium_104 -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3730|M.thermoresistible__bu GGDALGAAVKAAKEQLRSVPDGITYGLLRHLNPDVELGGAEPAIGFNYLG MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_3690|M.marinum_M -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MAB_2123|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2400c|M.bovis_AF2122/97 -------------------------------------------------- Rv2379c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4510|M.smegmatis_MC2_155 -------------------------------------------------- MAV_2014|M.avium_104 -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3730|M.thermoresistible__bu RLAAGAGDLPDELWRIDPSGLPITEAASKIPMPLAHTVEVNAGTLDAGPD MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_3690|M.marinum_M -------------------------------------------------- MUL_3633|M.ulcerans_Agy99 -------------------------------------------------- MAB_2123|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2400c|M.bovis_AF2122/97 -------------------------------------------------- Rv2379c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4510|M.smegmatis_MC2_155 -------------------------------------------------- MAV_2014|M.avium_104 -------------------------------------------------- Mflv_2697|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3844|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3730|M.thermoresistible__bu GPVLQATWTWAPSLVDEAQIARLSRLWFEALGGVCAHVRSGGGGLTPSDI MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_3690|M.marinum_M -----------MTAAAPQIEDVLALSPLQEGLFALHQLAEDG-------V MUL_3633|M.ulcerans_Agy99 -----------MTAAAPQIEDVLALTPLQEGLFALHQLAEDG-------V MAB_2123|M.abscessus_ATCC_1997 ---------MTGTEQQPQIEDVLALSPLQEGFFALSQLADES-------V Mb2400c|M.bovis_AF2122/97 ----MGPVAVTRADARGAIDDVMALSPLQQGLFSRATLVAAESGSEAAEA Rv2379c|M.tuberculosis_H37Rv ----MGPVAVTRADARGAIDDVMALSPLQQGLFSRATLVAAESGSEAAEA MSMEG_4510|M.smegmatis_MC2_155 ---------MTATGTPPGIEDVLALSPLQQGLYSLAGLTEEDTG-----A MAV_2014|M.avium_104 -------MTAAETDVAPDIEDVMALSPLQEGLYSLTTLAEFADGQ--PAD Mflv_2697|M.gilvum_PYR-GCK ----------MTAAKTGAIADVMALSPLQQGLYSLTAMSD--------GD Mvan_3844|M.vanbaalenii_PYR-1 ------MTQIQQSVEPPVIEDVLALSPLQQGLFSMATLSEGRD------D TH_3730|M.thermoresistible__bu APARLTQQQIDELADRHDIADILPLTPVQQGLLFHSAVTRTT------AD MLBr_02353|M.leprae_Br4923 ---------MITPDNAIAVVGMAGKFPGANDVSAFWTNLRRGKESIVTLS : .: * :.. MMAR_3690|M.marinum_M DLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAAFWDRDVPKPVQIV MUL_3633|M.ulcerans_Agy99 DLYSMQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAAFWDRDVPKPVQIV MAB_2123|M.abscessus_ATCC_1997 DLYSMQFVADIDGGLDVDLLHRSAQALLTRHPNLRAAFWDRGLPKPVQIV Mb2400c|M.bovis_AF2122/97 DPYVIAMAADAAGPLDIALLRDCAAAMLTRHPNLRASFLHGNLSRPVQVI Rv2379c|M.tuberculosis_H37Rv DPYVIAMAADAAGPLDIALLRDCAAAMLTRHPNLRASFLHGNLSRPVQVI MSMEG_4510|M.smegmatis_MC2_155 DPYVIAMAADIEGAVDPALLRSCAEAMLVRHPNLRASFFQGNLTRPVAVV MAV_2014|M.avium_104 DPYVIGMAADITGTLDVALLRDCAEKMLVRHPNLRASFFSRGIPRPVQIV Mflv_2697|M.gilvum_PYR-GCK DPYLIGMSADITGALDVSLLHDCAAAVLARHPNLRAGFFQGDLKRPVQVI Mvan_3844|M.vanbaalenii_PYR-1 DPYVIAMTADATGDLDARLLRECAAELLDRHANLRASFVKGNLSRAVQVI TH_3730|M.thermoresistible__bu DIYAVQLDLTIAGVVDQHRLRDAVHAVVARHPNLAARFCT-DHDHPVQII MLBr_02353|M.leprae_Br4923 EQELRDNGVSDKALADPAYVRR--APLLDGIDEFDADFFG-LPPLAAQVL : . * :: :: :: * * .. :: MMAR_3690|M.marinum_M PVHAALPWSERVATPAEFD------SIARSERRRPFDLSRGPALRVVVLS MUL_3633|M.ulcerans_Agy99 PVHAALPWSERVATPAEFD------SIARSERRRPFDLSRGPALRVVVLS MAB_2123|M.abscessus_ATCC_1997 PTHADIPWEEREAQPTEFD------EIALRERLRPFNLGKGPAIRLVLLT Mb2400c|M.bovis_AF2122/97 PSSAEVLWRHVRAHPSEVG------ALAAEERRRRFDVGRGPLIRFLLIE Rv2379c|M.tuberculosis_H37Rv PSSAEVLWRHVRAHPSEVG------ALAAEERRRRFDVGRGPLIRFLLIE MSMEG_4510|M.smegmatis_MC2_155 PTAVDLPWRHVTAPTAEAAA-----AIEAEERTRRFDLGRGPLIRFLLIE MAV_2014|M.avium_104 PSRVELPWRSVTASPAEVP------MLETAERRRPFDLERGPAIRFLLIE Mflv_2697|M.gilvum_PYR-GCK PEKVEVLWRHVRCDGTEVE------PLEREERARRFDLGRGPAMRFLLLE Mvan_3844|M.vanbaalenii_PYR-1 PKRVDLPWRHVTVAGDAELE-----AAERLERTTPFTLARGPVIRFLLIE TH_3730|M.thermoresistible__bu PTEPVAAWRYLDLRGDDQNPEHEVQQLCAAERAAVRDLTERPTFRAALIR MLBr_02353|M.leprae_Br4923 DPQHRLFLQCAWHALEDAG-------CDPAQFDGSIGVYGTSSPSGYLLH : : . :: MMAR_3690|M.marinum_M VPGETKRRMIFTAHHILVDGWSLAVFFTELLAVYRAGGAADALP-AARPY MUL_3633|M.ulcerans_Agy99 VPGETKRRMIFTAHHILVDGWSLAVFFTELLAVYRAGGAADALP-AARPY MAB_2123|M.abscessus_ATCC_1997 VPGESRHRMIVTSHHILMDGWAIAIFFSELLAVYQAGGSLAGLP-AVRPY Mb2400c|M.bovis_AF2122/97 LPD-ECWHLVIVAHHIVIDGWSLPLFVSELLALYRAGGHVAALPAAPRPY Rv2379c|M.tuberculosis_H37Rv LPD-ECWHLVIVAHHIVIDGWSLPLFVSELLALYRAGGHVAALPAAPRPY MSMEG_4510|M.smegmatis_MC2_155 MPA-QRWRLVVTAHHIAIDGWSLPVFVGEYITLYAADGDTAVFPAAPRPY MAV_2014|M.avium_104 LPD-AHWRLVLTAHHIVIDGWSLPVFVNELMTLYRAGGDRSALPAAPRPY Mflv_2697|M.gilvum_PYR-GCK TGQ-QRWRFVITAHHIVIDGWSLSLLVSELLALYRAAGNTSALPDAPRPY Mvan_3844|M.vanbaalenii_PYR-1 AP--QRWRFVVTAHHILIDGWSLPLFMGELLTLYRAGGDVTALPDPPRPY TH_3730|M.thermoresistible__bu TGA-TEHRFVLTVHHIVIDGWSLPILLQEIFAGYFG-----QRLPAPARF MLBr_02353|M.leprae_Br4923 NLLSHRDPHTVLAEGLNFDQFSLFLQNDKDFLATRISHAFNLRGPSIAVQ . . : .* ::: : : : . MMAR_3690|M.marinum_M RDYIVWLAKQDRSAALAGWMDYLRGVSEP--LMVAYEATAGQS-----KP MUL_3633|M.ulcerans_Agy99 RDYIVWLANQDRSAALAGWMDYLRGVSEP--LMVAYEATAGQS-----KP MAB_2123|M.abscessus_ATCC_1997 RDYIAWLNAQDTTEATARWTRYLGTVSGP--LMLADGAVAAHDN----VP Mb2400c|M.bovis_AF2122/97 RDYIGWLAGRDQTASRAMWADHLNGLDGPTLLSPALADTPVQPG----IP Rv2379c|M.tuberculosis_H37Rv RDYIGWLAGRDQTASRAMWADHLNGLDGPTLLSPALADTPVQPG----IP MSMEG_4510|M.smegmatis_MC2_155 RDYIGWLAGRDHDASRARWRAHLDGLDGPTLLAPALSGREAEPG----LP MAV_2014|M.avium_104 RDYIGWLAGRDLQASQRVWREHLAGLPGPTLLAASLGSAEATGGQRTALP Mflv_2697|M.gilvum_PYR-GCK RDYIGWLAARDQDHARSLWRAHLADLDGPTLLAPALGAATIGDG----LP Mvan_3844|M.vanbaalenii_PYR-1 RDYIGWLAGRDEETGRALWRRHLAGVDGPTLLTPALTSSAPTPG----RP TH_3730|M.thermoresistible__bu RDFVTWLAAQDRDAARAAWRELLDGFDTPTLIAPPGQAG---------PR MLBr_02353|M.leprae_Br4923 TACSSSLVALHLACLSLLSGECDMALAGGSSLCIPHRVGYWHS------P * . . : . MMAR_3690|M.marinum_M GKTELLLPAADTARLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFG MUL_3633|M.ulcerans_Agy99 GKTELLLPAADTARLRQWAGRHGLTLNTTVLFAWAVVLSRLTDRRDVVFG MAB_2123|M.abscessus_ATCC_1997 EKSQFLLAPEETARLRQWAAANGLTLNTVTAFAWALVLGRLTDRTDVVFG Mb2400c|M.bovis_AF2122/97 GRTEVRLDREATAELADAARTRGVTISTLVQMAWATTLSAFTGRGDVTFG Rv2379c|M.tuberculosis_H37Rv GRTEVRLDREATAELADAARTRGVTISTLVQMAWATTLSAFTGRGDVTFG MSMEG_4510|M.smegmatis_MC2_155 ARTEVTLDEQASAEIFDGARARGVTVNTLFQMAWAAILSAFTDRTDVVYG MAV_2014|M.avium_104 RTTELRMPAEATARLAAETRSRGITVNTLMQMAWALVLSRLTDTRDVVFG Mflv_2697|M.gilvum_PYR-GCK GMVELTADPSITEAVVDAARARGVTVNSLVQLAWALTLSSLTDRDDITFG Mvan_3844|M.vanbaalenii_PYR-1 RLTEVRLDAETTRQLAEAARSRGVTMNTLIQMAWATVLSVITDRTDVSFG TH_3730|M.thermoresistible__bu GSASYRIDTETTAAIGELARTQRTTVNTVLQAAWAHLLMAMTGQRDVVFG MLBr_02353|M.leprae_Br4923 GSMVSAVGHCRPFDVRADGTVFGSGVALVALKPLQAAIDASDRIHAVILG . : : . : : * MMAR_3690|M.marinum_M TVVSGRPDQLPGVETMVGLFINAVPVVHYVSGTEAVVAQCTQVQRQSSAM MUL_3633|M.ulcerans_Agy99 TVVSGRPDQLLGVETMVGLFINAVPVVHYVSGTEAVVAQCTQVQRQSSAM MAB_2123|M.abscessus_ATCC_1997 TIVSGRPKELPDVERMVGLFINSVPMVHHIDYSASVVEQCVQLQREAAAM Mb2400c|M.bovis_AF2122/97 VTVSGRPSELSGVETMIGLFINTVPLRVRLDARATVGGQCAVLQRQFAML Rv2379c|M.tuberculosis_H37Rv VTVSGRPSELSGVETMIGLFINTVPLRVRLDARATVGGQCAVLQRQFAML MSMEG_4510|M.smegmatis_MC2_155 VTVSGRPDELSGVESMVGLFINTVPLRIRLDPAGSVGEQCLAVQREAADL MAV_2014|M.avium_104 VTVSGRPPELTGVETMVGLFINTVPLRVRLDPAATVGEQCRAVQRDAALL Mflv_2697|M.gilvum_PYR-GCK VTVSGRPDDLAGVESMIGLFVNTVPLRVRLDPALTAGAQCRALQQDAATL Mvan_3844|M.vanbaalenii_PYR-1 VTVSGRPGELAGVERMVGLFINTVPLRVRLDPAAPAGEQCLALQREAAAL TH_3730|M.thermoresistible__bu TAVSGRPADLPGADRIVGLLINTIPVRARIGADTTVADLLAQLQHAHNDT MLBr_02353|M.leprae_Br4923 SAIN-----------------NDGSMKMGYAAPNPAAQADVIAEAHAVAG :. * .: .. : MMAR_3690|M.marinum_M RDVSYLSLSEIQREHG-RGPLFDSLFVFENAPIDDAIRPATTPDG----- MUL_3633|M.ulcerans_Agy99 RDVSYLSLSEIQREHG-RGPLFDSLFVFENAPIDDAIRPATTPDG----- MAB_2123|M.abscessus_ATCC_1997 RDIGYLSLSTLQRAEG-SAALFDTLFVFENAPIGDVVQEVEMADG----- Mb2400c|M.bovis_AF2122/97 RDHSYLGFNEFRAIAG-IGEMFDTLLVYENFPPGEVVGTAEFVAN----G Rv2379c|M.tuberculosis_H37Rv RDHSYLGFNEFRAIAG-IGEMFDTLLVYENFPPGEVVGTAEFVAN----G MSMEG_4510|M.smegmatis_MC2_155 RDHSYLSHTEIRALGG-IGELFDTLLVYENFPPGGLVGSDEFPLGSDGDG MAV_2014|M.avium_104 REHSYLGHAQLRALGG-IGEMFDTLLVYENFPMDGLTAGGELSAG----G Mflv_2697|M.gilvum_PYR-GCK RDHSYLGHAELRALAG-VGELFDTLLVYENFPPGAVAGAGTLEAA----G Mvan_3844|M.vanbaalenii_PYR-1 RDHGYLSHSELRALGG-IGELFDTLLVYENFPPGGLVGQARFEAN----G TH_3730|M.thermoresistible__bu LEHEHLALTEIHHLAG-HDQLFDTLFLYESYPIDTGAFSGAQELA----- MLBr_02353|M.leprae_Br4923 IDSSTVSYVETHGTGTPLGDPIEIQGLKTAFEVSQIPRPGPCVLG----- : :. : :: : . MMAR_3690|M.marinum_M AQFLPVEMESLTHYPLTVVSHLREDELLVLIEAIAEALPYLPAAEIGERM MUL_3633|M.ulcerans_Agy99 AQFLPVEMESLTHYPLTVVSHLREDELLVLIEAIAEALPYLPAAEIGERM MAB_2123|M.abscessus_ATCC_1997 ARFRPVEMESLAHYPLTVVSHMHGDSLLVLIEAIPQALPHVSGASVGERL Mb2400c|M.bovis_AF2122/97 VTFRPVALESLSHFPVTVAAHRSTGELTLLVEVLDGALGTMAPESLGRRV Rv2379c|M.tuberculosis_H37Rv VTFRPVALESLSHFPVTVAAHRSTGELTLLVEVLDGALGTMAPESLGRRV MSMEG_4510|M.smegmatis_MC2_155 AVLRPSALESLSHFPVTIAAHPTHGRLTVLVETLDGALGMLDPHALGRRV MAV_2014|M.avium_104 ATFRPSALQTLSHFPIAVAAHMEGGELVVLIEVVDGALGVIPADAVGRRL Mflv_2697|M.gilvum_PYR-GCK ATFTPVALQSLAHFPVTIAAHLTDGRLTVLVEAKDGALGQITPRALGTRL Mvan_3844|M.vanbaalenii_PYR-1 ATFVPSALESLSHFPVTIAAHLADDELTVFVEVIDGALGALRPGDLGRRV TH_3730|M.thermoresistible__bu --VTGFTNREFNHYPLSVMALPG-HELGLRIEYDTEVFDTAAIDALADRF MLBr_02353|M.leprae_Br4923 ----------------SVKSNIGHLEVAAGIAGLIKTILCLKNKAIPATL :: : : : .: : . MMAR_3690|M.marinum_M LTVLRQLPDIGDGTPDDLDIRTAAELKAHGLLAARSAPTFD---TTVWEM MUL_3633|M.ulcerans_Agy99 LTVLRQLPDIGDGTPDDLDIRTAAELKAHGLLAARSAPTFD---TTVWEM MAB_2123|M.abscessus_ATCC_1997 VSVLRQLPDIGGGTPDALELLTARER-AEIVVTASAADPSV---VSVWDL Mb2400c|M.bovis_AF2122/97 LAVLQRLVSRWDRPLRDVDILLDGEHDPTAPGLPDVTTSA----PAVHTR Rv2379c|M.tuberculosis_H37Rv LAVLQRLVSRWDRPLRDVDILLDGEHDPTAPGLPDVTTSA----PAVHTR MSMEG_4510|M.smegmatis_MC2_155 LTVVQRLLRSWDRPVRDVAVTLDDEVATVAP--TDTAVRP----GGFHTA MAV_2014|M.avium_104 LTTAERLLRHWERPLRAVSVLFDDEAAPLRAAGPIAPPSP----KCLPAR Mflv_2697|M.gilvum_PYR-GCK LATVSRIVEGWDRPLREISISPDDHPVPVPVSEAAPTPSPS---TGVHTR Mvan_3844|M.vanbaalenii_PYR-1 LHTAQRLISCWDAPLRSVGVLLPAEHTPAPMVREPLTANS------IHDR TH_3730|M.thermoresistible__bu RRVLESMVGDPARRLSAIEVLDAAEREQLDAWSNRAVLADSPALESIPEV MLBr_02353|M.leprae_Br4923 HYTSPNRELRLDQTPFVVQSNYGPWKWDGVRRAGVSSFGVGG--TNVHVV . : . MMAR_3690|M.marinum_M FERQVQATPDAVALTAAAG---VRHTYAELHARACRLAGELAEHGVGPET MUL_3633|M.ulcerans_Agy99 FERQVQTTPDAVALAAAGG---VRHTYAELHARACRLAGELAEHGVGPET MAB_2123|M.abscessus_ATCC_1997 FEREAQAHPESLALVADAG---TRYTYAQLRGAVSRLCAELIESGVTPET Mb2400c|M.bovis_AF2122/97 FAEIAAAQPDSVAVSWADG----QLTYRELDALADRLATGLRRADVSRET Rv2379c|M.tuberculosis_H37Rv FAEIAAAQPDSVAVSWADG----QLTYRELDALADRLATGLRRADVSRET MSMEG_4510|M.smegmatis_MC2_155 FTEAAAQRLGSIALTWDGG----ELTYRQLDEAADRVAAELRRRGVGTET MAV_2014|M.avium_104 FADVVAQTPDAPAVSWAQG----SLTYRELDEATNRLAAQLVALGVEPET Mflv_2697|M.gilvum_PYR-GCK FTETASARLGSVALSWDGG----ALTYRQLDEAADRLAAVLTASGVRTET Mvan_3844|M.vanbaalenii_PYR-1 FAGIAGDRLGSVALTWEAGGDSGTLTYRQLDEAADRMAVALTAAGVGPET TH_3730|M.thermoresistible__bu FARQVARDPGAVAVTFEGR----SMTYGELDDAATELANLLAVYGAGPGE MLBr_02353|M.leprae_Br4923 LEEASVEASTVAASTGPQVILLSAQTAAALGESREALATVLEKPGAPDLS : * * * :. * .. MMAR_3690|M.marinum_M VVALVLPRSERSIVAILGVLAAGGAYLPVDVTLPSARVESIVRQAS---- MUL_3633|M.ulcerans_Agy99 VVALVLPRSERSIVAILGVLAAGGAYLPVDVTLPSARVESIVRQAS---- MAB_2123|M.abscessus_ATCC_1997 TVALALPRSADSIIAILAVLAAGAAYVPVDIGLPAARVESILRQSN---- Mb2400c|M.bovis_AF2122/97 PVAVALSRGPRYVAAMLAVLKAGGMIVPLDPAMPGERVAEILRQTS---- Rv2379c|M.tuberculosis_H37Rv PVAVALSRGPRYVAAMLAVLKAGGMIVPLDPAMPGERVAEILRQTS---- MSMEG_4510|M.smegmatis_MC2_155 PVPIRLPRGPEYVVAMLGVLKAGGLIVPLDPAMPDERVDEIIRQTHP--- MAV_2014|M.avium_104 PVAIKLSRGPRYVVAMLAVLKAGGMCVPMEPGMPAPRVNSILRQSG---- Mflv_2697|M.gilvum_PYR-GCK PVAVRLRRGADYVVAMFAVLKAGGAIVPLDPAMPADRIEVILRRAG---- Mvan_3844|M.vanbaalenii_PYR-1 SVAVLLSRGPDYVVTMLGVLKAGGVIVPLDPAMPAERISDILEQSR---- TH_3730|M.thermoresistible__bu SVALLMPRSADAIVAILAVLKTGAAYLPIDPAVPAARLEFMLSDAEP--- MLBr_02353|M.leprae_Br4923 DVAYTLAGRRKHNITMAAVVRDREHAVTVLRAAEHDNVFVGESGADTGRS *. : :: .*: :.: .: : MMAR_3690|M.marinum_M ----PALAITEADYSQLVGTAVPTLALDDPAAVESISRRSAAAPTVDRRP MUL_3633|M.ulcerans_Agy99 ----PALAITEADYSQLVGTAVPTLALDDPAAVDSISRRSAAAPTVDRRP MAB_2123|M.abscessus_ATCC_1997 ----PTLVITVDRHRDIAGRGYQVLILDDPETAARISGRSESGHAVVVHR Mb2400c|M.bovis_AF2122/97 ----APVVIDEGVFAAS--VGADILEDDRA---------------ITVPV Rv2379c|M.tuberculosis_H37Rv ----APVVIDEGVFAAS--VGADILEEDRA---------------ITVPV MSMEG_4510|M.smegmatis_MC2_155 -DGRQPAIVDDAFVAAVRAADAELPADYRP---------------AHVHP MAV_2014|M.avium_104 ----ASIVLDEERIDELLEAGRSQHGGFEP---------------PDIPP Mflv_2697|M.gilvum_PYR-GCK ----VTVVVDEDTVARA---TAEPPAQYRP---------------AETLP Mvan_3844|M.vanbaalenii_PYR-1 ----ASVVVDDAFVAAVP--DVEPPAGYRP---------------AEVTA TH_3730|M.thermoresistible__bu ----IVALTTVELGTRFNGTGVPIIEVDDPAPP-----MYPSSTLLPPAP MLBr_02353|M.leprae_Br4923 AAASITTLGSDRVVFLFPGQGAQHVGMAKG--------------LYDTES MMAR_3690|M.marinum_M EQSAYVIFTSGSTGEPKGVVGTNAAVLSYFADHAERVYRAARARLGRPLR MUL_3633|M.ulcerans_Agy99 EQSAYVIFTSGSTGEPKGVAGTNAAVLSYFADHAERVYRAARARLGRPLR MAB_2123|M.abscessus_ATCC_1997 DQSAYLIFTSGSTGEPKGVVGTHAALMSYFADHRDRVYRPATARLGRKLR Mb2400c|M.bovis_AF2122/97 DQAAYVIFTSGTTGTPKGVIGTHRALSAYADDHIERVLRPAAQRLGRPLR Rv2379c|M.tuberculosis_H37Rv DQAAYVIFTSGTTGTPKGVIGTHRALSAYADDHIERVLRPAAQRLGRPLR MSMEG_4510|M.smegmatis_MC2_155 GQGAYIVFTSGTTGKPKGVIGTHQALLAYAADHARNVLRPAAQRVGHPLR MAV_2014|M.avium_104 AQAAYVVFTSGTTGEPKGVIGTHGAVGAYADDHLDRVLRPAAAALGRPLR Mflv_2697|M.gilvum_PYR-GCK GQAAYVVFTSGTTGEPKGVIGTHRALLAYADDHIGAILRPAADRVGRPLR Mvan_3844|M.vanbaalenii_PYR-1 DRAAYIVFTSGTTGRPKGVVGTHGAVLGYAEDHAEQVLRPAAARIGRPLR TH_3730|M.thermoresistible__bu DDIAYLIYTSGTTGVPKGVAITHANVTRVLHTLPADLP----AGPGKVWS MLBr_02353|M.leprae_Br4923 VFAEHFDTCSAGFREAMDDLDLHSAIFNGTAIDLERIDRSQPALFTVEYA :. *. . . : : : MMAR_3690|M.marinum_M IAHAWSLSFDASWQPMVGLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDM MUL_3633|M.ulcerans_Agy99 IAHAWSLSFDASWQPMVGLLDGHEIHLFDADEMRDADRLVEGIAIGQIDM MAB_2123|M.abscessus_ATCC_1997 IAHAWSLSFDASWQPMIGLLDGHAVHLFDAEAMRDASLLVRGMAERGVDM Mb2400c|M.bovis_AF2122/97 IAHAWSFTFDAAWQPLVALLDGHAVHIVDDHRQRDAGALVEAIDRFGLDM Rv2379c|M.tuberculosis_H37Rv IAHAWSFTFDAAWQPLVALLDGHAVHIVDDHRQRDAGALVEAIDRFGLDM MSMEG_4510|M.smegmatis_MC2_155 VAHAWSFTFDAAWQPLVALLDGHANHIVGDDVQRDAEALVETIGRHAIDM MAV_2014|M.avium_104 IAHAWSFAFDAAWQPLVALLDGHGVHVVDEATQTDAEALVALIAEHGVDM Mflv_2697|M.gilvum_PYR-GCK IAHAWSFTFDAAWQPLAALLDGHSVHIVDDATQRDAEALVDTIARFGVDM Mvan_3844|M.vanbaalenii_PYR-1 VGHAWSFTFDAAWQPLAALLDGHSVHLLGEESQRDAEALVYRIGRFGIDM TH_3730|M.thermoresistible__bu QWHSLVFDVS-VWEIWGALLHGGRLVIVPESITGSPDDLHDLLVAEHVDV MLBr_02353|M.leprae_Br4923 LAK-LVESFGVGAGAYIGYSTGEYIAATLAG-VFDLETAIKTVSLRARLM : .. . * . : : MMAR_3690|M.marinum_M IDTTPSMFVQLSAAGLLDHN-LSVLALGGEAINTGLWDQLR---GLSQMA MUL_3633|M.ulcerans_Agy99 IDTTPSMFVQLSAAGLLDHN-LSVLALGGEAINTGLWDQLR---GLSQMA MAB_2123|M.abscessus_ATCC_1997 IDTTPSMLAQLSAAGLLDHE-LAVLALGGEAIETALWDRLR---SLSDTA Mb2400c|M.bovis_AF2122/97 IDTTPSMFAQLHNAGLLDRAPLAVLALGGEALGAATWRMIQQNCARTAMT Rv2379c|M.tuberculosis_H37Rv IDTTPSMFAQLHNAGLLDRAPLAVLALGGEALGAATWRMIQQNCARTAMT MSMEG_4510|M.smegmatis_MC2_155 IDTTPSMFTQLRAAGLLSTVPLAVLALGGEAIDTALWQAIQAECERTWMS MAV_2014|M.avium_104 IDTTPSMFAQLQAFGLLSEAPLTVLALGGEALGNAAWARIRNACNTTTMS Mflv_2697|M.gilvum_PYR-GCK IDTTPSMFARLRDVGLLSTVPLAVLALGGEAVDPGLWQQIRQECARTGMS Mvan_3844|M.vanbaalenii_PYR-1 LDTTPSMFAQLHDVGLLSTVPLAVLALGGEAVSPATWRLIGDECARTGMT TH_3730|M.thermoresistible__bu VYQTPSAAGMLSQRGLDSTA----LVVAGEACPTDLVDRWAP-----GRV MLBr_02353|M.leprae_Br4923 HESPPGAMVAVALG--PEDITEYLAEYSAKGVELSAVNDPGNCVVAGPKD .*. : . ..:. MMAR_3690|M.marinum_M VYNCYGPTEMTVEAVVAAVKDYRK--PTIGTANAGTFGYVFDSALRMVPD MUL_3633|M.ulcerans_Agy99 VYNCYGPTEMTVEAVVAAVKDYRK--PTIGTANAGTFGYVFDSALRMVPD MAB_2123|M.abscessus_ATCC_1997 VYNCYGPTETTVEAVVAAVKEYPA--PTIGTPNQGMVGYVLDSRLRPVPD Mb2400c|M.bovis_AF2122/97 AFNCYGPTETTVEAVVAAVAEHAR--PVIGRPTCTTRAYVMDSWLRPVPD Rv2379c|M.tuberculosis_H37Rv AFNCYGPTETTVEAVVAAVAEHAR--PVIGRPTCTTRAYVMDSWLRPVPD MSMEG_4510|M.smegmatis_MC2_155 AHNCYGPTEATVEAVVAAIADHRD--PCIGKPTDPTAAYVLDSWLRPVPA MAV_2014|M.avium_104 AYNCYGPTETTVEAVVAAIAEHAE--PSIGRPTRHTRGYVLDSELRPVPC Mflv_2697|M.gilvum_PYR-GCK AFNCYGPTETTVEAVVAEIGAHER--PTIGRPTAPTRAYVLDSWLRPVPS Mvan_3844|M.vanbaalenii_PYR-1 AFNCYGPTETTVEAVVAPIDGYQR--PSIGQPTRTMRTYVLDAWLRPVPD TH_3730|M.thermoresistible__bu MINAYGPTETTMCVAISAPLTPGSGAVPIGTPVPRAALFVLDSWMRPVPA MLBr_02353|M.leprae_Br4923 QIRAFSQRLDEVGIPVRRVRATHAFHTSSMEPMLREFSEFLSRQQLRVPN ..:. : : . .:. ** MMAR_3690|M.marinum_M GVVGELYLSGAQLARGYVGRPGMTAARFVADPLRP-GQRMYRTGDLVRRL MUL_3633|M.ulcerans_Agy99 GVVGELYLSGAQLARGYVGRPGMTAARFVADPLRP-GQRMYRTGDLVRRL MAB_2123|M.abscessus_ATCC_1997 GAVGELYLAGAQLARGYAGKPAVTAAAFVADPRRA-GQRMYRTGDLVRRL Mb2400c|M.bovis_AF2122/97 GVAGELYLAGAQLTRGYLGRPAETAARFVAEPNGR-GSRMYRTGDVVRRL Rv2379c|M.tuberculosis_H37Rv GVAGELYLAGAQLTRGYLGRPAETAARFVAEPNGR-GSRMYRTGDVVRRL MSMEG_4510|M.smegmatis_MC2_155 GVAGELYLAGGQLTRGYVGRPGETAARFVADPFTL-GARMYRTGDVVRRT MAV_2014|M.avium_104 GATGELYLGGAQLARGYLGRAGETASRFVADPFAA-SERMYRTGDLVRRL Mflv_2697|M.gilvum_PYR-GCK GAAGELYLAGGQLTRGYLGRPGETAARFVPDPFVP-GARMYRTGDVVRRA Mvan_3844|M.vanbaalenii_PYR-1 GVAGELYLSGRQLTRGYLGRAAETAGRFVADPFTP-GQRMYRTGDVVRRG TH_3730|M.thermoresistible__bu GVIGELYVAGDGVAVGYVGRSELTASRFVACPFGPPGSRMYRTGDLVRWG MLBr_02353|M.leprae_Br4923 ------TPLLSNLTGTWMSEQQVTDPENWTRQISS-TIRFADELDVVLSQ :: : .. * . *: *:* MMAR_3690|M.marinum_M SHGGYAYVGRAD--TQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQ MUL_3633|M.ulcerans_Agy99 SHGGYAYVGRAD--TQVKIRGYRVEVGEIEAALRGQPGVHDAAVSVLRQQ MAB_2123|M.abscessus_ATCC_1997 PHGGFAYLGRAD--SQVKIRGYRVEVGEIESALRLQPDIQTAAVTVVRRA Mb2400c|M.bovis_AF2122/97 PDGGLEFLGRSD--DQVKIRGFRVEPGEIAAVLNGHHAVHGCHVTARGHA Rv2379c|M.tuberculosis_H37Rv PDGGLEFLGRSD--DQVKIRGFRVEPGEIAAVLNGHHAVHGCHVTARGHA MSMEG_4510|M.smegmatis_MC2_155 PDGALQFLGRSD--DQVKIRGFRVEPGEVAAALHRHPQVRHAHVALRRHR MAV_2014|M.avium_104 PDGSLQYVGRAD--AQVKIRGHRVEPGEIAAALESHPAVRHAGVLVRHRD Mflv_2697|M.gilvum_PYR-GCK VDGTLAFLGRSD--TQVKIRGFRVEPGEVAAVLRTHPAVGQAYVAVRPHR Mvan_3844|M.vanbaalenii_PYR-1 ADGGLQFLGRAD--NQVKIRGFRVEPGEIAAVLSGHPAVTDAHVVVDRVG TH_3730|M.thermoresistible__bu ADGQLQYLGRAD--EQVKIRGYRIELGEVQTALTAVDGVENAVVIAREDR MLBr_02353|M.leprae_Br4923 SGRVLVEVGPGGSLTGSAMRHPRWSSGHRAVRLMRHPLQNVDDHDTFLRA :* .. :* * . *. * MMAR_3690|M.marinum_M DR-TSLVGFVVWQDNMHEDLI--KLRAGLTERLPSYMVPARIVTLPRLPV MUL_3633|M.ulcerans_Agy99 DR-TSLVGFVVWQDNMHEDLI--KLRAGLTERLPSYMVPARIVTLPRLPV MAB_2123|M.abscessus_ATCC_1997 GG-ASLVGFVVCEKDTFDSAR--TMMR-LADRLPSYMMPSRLVPLPQLPV Mb2400c|M.bovis_AF2122/97 SG-PRLTAYVAGGPQPPPVA---ELRAMLLERLPRYLVPHHIVVLDELPL Rv2379c|M.tuberculosis_H37Rv SG-PRLTAYVAGGPQPPPVA---ELRAMLLERLPRYLVPHHIVVLDELPL MSMEG_4510|M.smegmatis_MC2_155 SG-PRLVAYVVTDASLADAAG--ELRRMLAATLPRYLVPHHILLVDEIPL MAV_2014|M.avium_104 GA-PRLTGYVATHEAAPDTPSPAELRGMLSARLPRYMVPQRIIMVDEIPL Mflv_2697|M.gilvum_PYR-GCK DG-HRLTAYVTGEPQLR------ELRAWLGRRLPRYLMPNAIVAVDRIPL Mvan_3844|M.vanbaalenii_PYR-1 TQ-TRLIAYVAAATPPAVAD----LRELMAKRLPRYMVPQRVVVLDELPL TH_3730|M.thermoresistible__bu PGDKRLVGYITGTADPD------QARARLADRLPAYMVPTAVVVLDALPL MLBr_02353|M.leprae_Br4923 LGELWSAGIEVDWAPQRSVMPHLVSLPGYPFARQRHWVEPRYTIWAQIPG . . : : :* MMAR_3690|M.marinum_M NANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLN-AV MUL_3633|M.ulcerans_Agy99 NANGKLDGHALDRLAEDALTSVSGGTAVSASTDTERVLCELFEEQLN-AV MAB_2123|M.abscessus_ATCC_1997 TVNGKLDGGALERLAREALSGGAVGEQAQPATATECVLCECCAELFDGTA Mb2400c|M.bovis_AF2122/97 TPHGKIDENALAAIN------VTEGPATPPQTPTELVLAEAFADVMETSN Rv2379c|M.tuberculosis_H37Rv TPHGKIDENALAAIN------VTEGPATPPQTPTELVLAEAFADVMETSN MSMEG_4510|M.smegmatis_MC2_155 TTNGKVDDARLAALDSG----RQSGGFQGPATDTERVVAEVLAEVLDTRA MAV_2014|M.avium_104 TPNGKLDETALAAVDNA----EAVDGAATPQTGTESALAELIAELLGQPR Mflv_2697|M.gilvum_PYR-GCK TAHGKIDEPALVALEP-----AADGAATRPQTPTEVELAAVLAEVLGVGE Mvan_3844|M.vanbaalenii_PYR-1 TSHGKIDEAALAGIA------VEDAPSAAPETPTETALVELMAEVLGDDG TH_3730|M.thermoresistible__bu TVNGKLDTRALPAPEY-----QDAEQYRAPTHAVEEVLAGIYAEVLGIDK MLBr_02353|M.leprae_Br4923 ASSGSPVDSSVDSAT--------VEGVRGGESQTEATLQRIWSQCLGVSS *. : .* : : : MMAR_3690|M.marinum_M PHIDDDLFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAID MUL_3633|M.ulcerans_Agy99 PHIDDDLFLFGMDSIVAISLVHKARRQGLRVDPRMVLTATTIRQLGAAID MAB_2123|M.abscessus_ATCC_1997 PGIDEDFFSLGVDSIVAISLVNKARKRDLVITPRMVLAAPTIRQLAALVD Mb2400c|M.bovis_AF2122/97 VDVTAGFLQMGLDSIVALSVVQAARRRGIALRARLMVECDTIRELAAAID Rv2379c|M.tuberculosis_H37Rv VDVTAGFLQMGLDSIVALSVVQAARRRGIALRARLMVECDTIRELAAAID MSMEG_4510|M.smegmatis_MC2_155 VDVTAEFLDLGLDSIVALTVVQAVRRRGLALRARLMLECANVRELAAAID MAV_2014|M.avium_104 VDVTADFLALGLDSIMALSVVQAARARGIALRARLVLDCTSIRELAEAID Mflv_2697|M.gilvum_PYR-GCK IDVTADFLELGLDSIVALSVVQTARRRGVVMRAKLMLDCATVRELAAAID Mvan_3844|M.vanbaalenii_PYR-1 IDVEADFLEMGLDSIVALTLVQAARRRGLEMRARLMLECNTIRELATAID TH_3730|M.thermoresistible__bu VGVDDSFFDLGGDSISSMQVVARARAAGLTIRPRDIFVERTVARLAQVAV MLBr_02353|M.leprae_Br4923 VDRNANFFDLGGDSLMAISISMAAANEGMTITPQDMYEHPTLASLTAAVD :: :* **: :: : . .: : .: : .: * MMAR_3690|M.marinum_M AAVD--SQDAPADADYGAVRPLPMVSWLYEYG-NYRRFTHTVLLRLPSGI MUL_3633|M.ulcerans_Agy99 AAVD--SQDAPADADYGAVLPLPMVSWLYEYG-NYRRFTHTVLLRLPSGI MAB_2123|M.abscessus_ATCC_1997 TRGH--VDSLAGEADYGEVPPLPVVSWMYESE-IYRRLSLSVLVRLPAGI Mb2400c|M.bovis_AF2122/97 SDAA-WQAPAN--DAGEPIPVLPNTHWLYEYG-DPRRLAQTEVIRLPDRI Rv2379c|M.tuberculosis_H37Rv SDAA-WQAPAN--DAGEPIPVLPNTHWLYEYG-DPRRLAQTEVIRLPDRI MSMEG_4510|M.smegmatis_MC2_155 ADAH-HAAVDHTPEDSGPIPLLPNGSWLYQYG-EPRRLAQTEAFRLPEGT MAV_2014|M.avium_104 AEST-PAAGEVD-DGTGPMPLLPNGRWLYEHG-QPRRLAQTEAIRVPQTL Mflv_2697|M.gilvum_PYR-GCK DAGS-GPPSAD--EGSGPIALLPNAHWLYEFG-DPRRLASTEALRLPRGI Mvan_3844|M.vanbaalenii_PYR-1 SGAHDHAPAAVTDDRFGEVMPAPIMSWMYECG-NYRRFTQNVLVSLPADI TH_3730|M.thermoresistible__bu PTGA---DAAVDDAGTGPVVATPIMRWLYDTRGPIDQFNQTVVLRAPAGV MLBr_02353|M.leprae_Br4923 ASFASSGLAKPPEAAAHPAVPPNIAYFLERGLCDTGRWRVPLILRLDPKI :: : . MMAR_3690|M.marinum_M DRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRIT MUL_3633|M.ulcerans_Agy99 DRSSIELMLQLLLDGHDTLRSILTETPEGPRLVTREPAAVRAEDVLTRIR MAB_2123|M.abscessus_ATCC_1997 DRPGIERMLQLLLDGFTMLRSTLVDTPDGARVVTREPGVVRGESVLSRVE Mb2400c|M.bovis_AF2122/97 TRERLDAVLAAVVDGHEVLRCRFDR--DAMALVAQPKTDI---LSEVWVS Rv2379c|M.tuberculosis_H37Rv TRERLDAVLAAVVDGHEVLRCRFDR--DAMALVAQPKTDI---LSEVWVS MSMEG_4510|M.smegmatis_MC2_155 TAAQLRTLLRTVVDGHEVLRTRLDR--VTRTLVPHGPRDV---LTEAVGV MAV_2014|M.avium_104 RRDQLETALAGIIDGHEVLRSRVDR--ATMTLVPGPAPDIGKELEEVAVV Mflv_2697|M.gilvum_PYR-GCK TGPQIRALLQSVVDAHPVLRTRLDR--AAMTLVDGG-FDLP--LTEIEVG Mvan_3844|M.vanbaalenii_PYR-1 TDSRLEQILQALLDRHDMLRAILD---ERGRLVTRPPGAVRVADVLRVVD TH_3730|M.thermoresistible__bu TEADVVEILQAVLDRHAMLRLRAADVENLTVPESGAVTARGCLRTVHRLS MLBr_02353|M.leprae_Br4923 GSDDIRAVLTAVVNHHDVLRLSLVDNDGMWEQHIAATGEFTRLLTQTLPD : * ::: . ** MMAR_3690|M.marinum_M LPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANIL MUL_3633|M.ulcerans_Agy99 LPEGSDDELASAVAHAARVVTDQIDPSAGAMVRAIWFRGTEHRADPANML MAB_2123|M.abscessus_ATCC_1997 LPTG--ESAHAAITNAARQAFDSLDPRSGAMMRAVWLAS----RDSGDVL Mb2400c|M.bovis_AF2122/97 ------GELVTAVAEQTLGVLASLDPQAGRLLSAVWLR---EPDGPG-VL Rv2379c|M.tuberculosis_H37Rv ------GELVTAVAEQTLGALASLDPQAGRLLSAVWLR---EPDGPG-VL MSMEG_4510|M.smegmatis_MC2_155 ------GTLADAVAEQAALSVDRIDPQQGSMLDAVWLR---HPDAPGGVF MAV_2014|M.avium_104 ------GDLRAAVADRAARAIDRLDPERGVLLGAVWLR---PADGDG-VL Mflv_2697|M.gilvum_PYR-GCK ------DEGSAAVARHAAAALEHLDPQRGPLWGAVWLRGSDDADSTSSVL Mvan_3844|M.vanbaalenii_PYR-1 ------AAAHTVLAAEVVAALDRIDPTSGAMVQAVWFR-----HGPP-VL TH_3730|M.thermoresistible__bu -------------GDELRSARAELDPAAGTMVRALWAP-------DTRRL MLBr_02353|M.leprae_Br4923 G----VAAGSAEERAVVSSILAELIASQSDLNEPLTAVQITTAHGGPHYL : . . : .: : MMAR_3690|M.marinum_M LLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELM MUL_3633|M.ulcerans_Agy99 LLTAHHLAVDVVSWHIMLGDLAAAWRSLQAGTPPKILPEFTSYRRWCELM MAB_2123|M.abscessus_ATCC_1997 LLTVHHLAMDVVSWHIVLGYLADAWIAVRSGTAPKAPMEFTSYRQWSQLM Mb2400c|M.bovis_AF2122/97 VLTAHVLAMDPASWRIVLGELDAGLHALAAGRAPSPARENTSYRQWSRLL Rv2379c|M.tuberculosis_H37Rv VLTAHVLAMDPASWRIVLGELDAGLHALAAGRAPSPARENTSYRQWSRLL MSMEG_4510|M.smegmatis_MC2_155 ILTAHVLALDPASWRIVVGELETAWHALASGREPTPVREHTSLRRWSRML MAV_2014|M.avium_104 LLTAHVIALDPASWRVVLGELGAALTAAATGHSPAAVREHTSYRRWAHAL Mflv_2697|M.gilvum_PYR-GCK LLTAHVLAMDPVSWQIVIGELDAGWHALAGGRAPAALGEHTGYRQWSNLL Mvan_3844|M.vanbaalenii_PYR-1 ALCVHHLSTDVVSWYLILGALAQIDATLAAGHAPDPAAEYTTYREWTRRL TH_3730|M.thermoresistible__bu ALIVHHLAVDAVSWRILVEDINIAWGQRHTGQPIDLPAGGTSFARWSTLL MLBr_02353|M.leprae_Br4923 GLAVHQMVIDDASRQILGTDIITAFGQRLAGEEITLEPVTTGWREWSLRC * .* : * .* :: : * * .* MMAR_3690|M.marinum_M WHRASAPQVQDQRDYWAALVREP---DPALGLRYPDPTRDTWSTLQLTRA MUL_3633|M.ulcerans_Agy99 WHRASAPQVQDQRDYWAALVREP---DPELGLRYPDPTRDTWSTLQLTRA MAB_2123|M.abscessus_ATCC_1997 HQRASSHDVLRQRDYWAEQVSGA---DPELGSRHADPSRDTWGTLQTTAV Mb2400c|M.bovis_AF2122/97 AQRAKALDS---VDFWVAELEGA---DPPLGARRVAPQTDRVGELAITMS Rv2379c|M.tuberculosis_H37Rv AQRAKALDS---VDFWVAELEGA---DPPLGARRVAPQTDRVGELAITMS MSMEG_4510|M.smegmatis_MC2_155 SERALKLDT---VDFWHRQFDGA---DPDIGARRVDPATDRMRDIAVEMT MAV_2014|M.avium_104 TARAHRLDT---VGFWASELDGD---DPDLGARRVDPARDRARDLLVRNV Mflv_2697|M.gilvum_PYR-GCK RERAESSDG---LQFWLDQLGGP---DPALGARRVRPDTDRAGDVRVTVT Mvan_3844|M.vanbaalenii_PYR-1 YQRSRTEAVERRRGFWVEQLAGS---DPLLGRRLPDPRHDTWSTLQSTDV TH_3730|M.thermoresistible__bu AEYADTPEVVAQAGVWQQVAAXX---WPSCSTP----------------- MLBr_02353|M.leprae_Br4923 AALATHPAALDTRSFWIENANKVNLWLADVSLNTDVIQPPGADDLIRMPC : * . . MMAR_3690|M.marinum_M AIPVDVTERVLGAVR-RDQGVRELLLAATAMAVASWRRVRAQDPAAGVLV MUL_3633|M.ulcerans_Agy99 AIPVDVTERVLGAVR-RDQGVRELLLAATAMAVASWRRVRAQDPAAGVLV MAB_2123|M.abscessus_ATCC_1997 PTPVAVTTRLLASLN-KPEGVYSFLLSALAVTVASWRKLRGQDSTAGTLV Mb2400c|M.bovis_AF2122/97 ISDADLTARLLS----TGRSMTDLLATAAARMVTAWRRQRGQQTPA-PLL Rv2379c|M.tuberculosis_H37Rv ISDADLTARLLS----TGRSMTDLLATAAARMVTAWRRQRGQQTPA-PLL MSMEG_4510|M.smegmatis_MC2_155 FADADLTARLLT----GGVPVTEVLAAATARTVTAWRRERGQPTPA-PLL MAV_2014|M.avium_104 ATDADLTRRLLE----SGLPLPTLLVAATAATVTRWRRQRGQSTPP-PLL Mflv_2697|M.gilvum_PYR-GCK VTGADVTARLLA----GPHPVLDVLVAALGRTITEWRGRRNQPTPP-PLV Mvan_3844|M.vanbaalenii_PYR-1 VTDAGATRAILDRLDGASLEVRDFLLTALTLTLASWRIERGQPAHHGALV TH_3730|M.thermoresistible__bu --------------------------TTTSSSTSTWRSTRSTGRPVRTGC MLBr_02353|M.leprae_Br4923 TLSVEQTSELDDARRRFRRSIQAIVLAALGRTIAQTVGDG--------VV :: : MMAR_3690|M.marinum_M ALEGHGRADAVLDT---------DTTNTVGWFTNAFPVRLGAGAAAVDIE MUL_3633|M.ulcerans_Agy99 ALEGHGRADAVLDT---------DTTNTVGWFTNAFPVRLGAGAAAVDIE MAB_2123|M.abscessus_ATCC_1997 SLEGHGRADGELDT---------DTSGTVGWFTTVYPVRVAAGEAAIDVD Mb2400c|M.bovis_AF2122/97 ALETHGRADVHVDK-------TADTSDTVGLLSAIYPLRIHCDGA----- Rv2379c|M.tuberculosis_H37Rv ALETHGRADVHVDK-------TADTSDTVGLLSAIYPLRIHCDGA----- MSMEG_4510|M.smegmatis_MC2_155 ALETHGRADAVVSADLGEDPHQVDTGDTAGLLSMIYPLRVTAGDA----- MAV_2014|M.avium_104 ALETHGRADSLVDG---PGAHTIDTGDTVGLLSSIYPIRVDAADP----- Mflv_2697|M.gilvum_PYR-GCK ALETHGRAALAEADT-ADTADTADTSDTVGLLSAIYPLRLHEDSP----- Mvan_3844|M.vanbaalenii_PYR-1 ALEGHGREDALVGG-------GVDTSATVGWFTSVYPVRLGAGEAAIDVD TH_3730|M.thermoresistible__bu STRCS-------------------STRTIRSMRRRWPGRKALRSP----- MLBr_02353|M.leprae_Br4923 AVELEGEGRSVLRP-------DVDVRRTIGWFTNYYPIPLVCVKGQ---- : . * : :* MMAR_3690|M.marinum_M QAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYVDGV--AELVDAVDP MUL_3633|M.ulcerans_Agy99 QAERDPVAAQDLVHSVVSHLEAIPNDGLDYGLLRYVDGV--AELVDAVDP MAB_2123|M.abscessus_ATCC_1997 RMENDVNAARQLLAGVARHIDEIPYQGLDYGLLRYVRGC--EELSSARDP Mb2400c|M.bovis_AF2122/97 -------------TDFAR----IPGSGIDYGLLRYLRADTAERLRAHREP Rv2379c|M.tuberculosis_H37Rv -------------TDFAR----IPGSGIDYGLLRYLRADTAERLRAHREP MSMEG_4510|M.smegmatis_MC2_155 -------------RGVAELVAAIPGDPIDYGLLRHLREDTAESLGVHRDP MAV_2014|M.avium_104 -------------RRVADKLAAIPGDGLDYGLLRYLRDDTAERLAALPSP Mflv_2697|M.gilvum_PYR-GCK -------------GATTELIAGVPAGGIDYGLLRYLRPDTSEVLKAHPEP Mvan_3844|M.vanbaalenii_PYR-1 TAARNPAAARSLLRAVIQQLAEVPDKGLDYGLLRYTRRD--ETLRALPEP TH_3730|M.thermoresistible__bu -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------GALAQLDAVHNTLKSIPHYGIGYGLLRYMYAPTGRVFSAQRTP MMAR_3690|M.marinum_M QIQFSYLGRLDLGGVADQP--WSLLTGPYLDALPIDPEPDLPLRFALNLS MUL_3633|M.ulcerans_Agy99 QIQFSYLGRLDLGGVADQP--WSLLTGPYLDALPIDPEPDLPLRFALNLS MAB_2123|M.abscessus_ATCC_1997 QIQFNYVGRMDISGIDDQP--WSLITDARSLAVPPDSEPDLPLRFAINIG Mb2400c|M.bovis_AF2122/97 QLLLNYLGSLHVGVGD------LAVDRALLADVGQLPEPEQPVRHELTVL Rv2379c|M.tuberculosis_H37Rv QLLLNYLGSLHVGVGD------LAVDRALLADVGQLPEPEQPVRHELTVL MSMEG_4510|M.smegmatis_MC2_155 QLLLNYLGRIELDSADH----ALLQDRSLLSGVTPIPEPDVAVRHELTIM MAV_2014|M.avium_104 QLLLNYLGAAHTDGGTG-----LTLERELLAGLSPIPEPDLAVRHELTIA Mflv_2697|M.gilvum_PYR-GCK QILLNYLGRTDLVPSG-----AIVADRLLLSGLSTVPEPNAAVRHELTVV Mvan_3844|M.vanbaalenii_PYR-1 QVEFNYIGRYDLSADQTSQAWSLITDETLNAHMPAAAEPDLPLRYTFDVI TH_3730|M.thermoresistible__bu --------------------------------------------ISRAAN MLBr_02353|M.leprae_Br4923 DIHFRYVGVVPEPPSVDAT--VQFDSDMTIPVQEPVPGMGHAIELRTYRF MMAR_3690|M.marinum_M VFVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLWQRGIAALAAGLD--- MUL_3633|M.ulcerans_Agy99 VFVGVTAEGTQLIGNWRWSDAVFERSDIDHLTGLWQRGIAALAAGLD--- MAB_2123|M.abscessus_ATCC_1997 SAVMTTPEGPQLLTNWQLSSALFTPADASRLAQLWQRSVAALAGALDG-- Mb2400c|M.bovis_AF2122/97 AALLGPADAPVLATRWRTLPDILSADDVATLQSLWQGALAEITA------ Rv2379c|M.tuberculosis_H37Rv AALLGPADAPVLATRWRTLPDILSADDVATLQSLWQGALAEITA------ MSMEG_4510|M.smegmatis_MC2_155 AAVIDRDGSAVLGAQWRTLPDILSAAEVGTLQTMWLDALREVVE------ MAV_2014|M.avium_104 AMVLTYGGQRVLAAQWRTLPDILTDTDITALQELWVDSLREMVT------ Mflv_2697|M.gilvum_PYR-GCK AAVVAHGDEPALVAQWRVLPEILSDTDVEEMQTIWQDTLREVL------- Mvan_3844|M.vanbaalenii_PYR-1 SVISGGADGPQLRTSWRWSTALSTSTEVDRLTALWQQAVTVLGEAL---- TH_3730|M.thermoresistible__bu TTTIRCRWSQCPGTSSDCASNTTPRCSTPRMSRHWSAGCGGC-------- MLBr_02353|M.leprae_Br4923 GGSLHLDWWYDIRRIPQVTAEALAQSFPVTLSKLIQEGIATQKDAHDESE : MMAR_3690|M.marinum_M ------------------- MUL_3633|M.ulcerans_Agy99 ------------------- MAB_2123|M.abscessus_ATCC_1997 ------------------- Mb2400c|M.bovis_AF2122/97 ------------------- Rv2379c|M.tuberculosis_H37Rv ------------------- MSMEG_4510|M.smegmatis_MC2_155 ------------------- MAV_2014|M.avium_104 ------------------- Mflv_2697|M.gilvum_PYR-GCK ------------------- Mvan_3844|M.vanbaalenii_PYR-1 ------------------- TH_3730|M.thermoresistible__bu ------------------- MLBr_02353|M.leprae_Br4923 MAGAPQAGVLVDLSTLDAG