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TQIQQSVEPPVIEDVLALSPLQQGLFSMATLSEGRDDDPYVIAMTADATGDLDARLLRECAAELLDRHAN LRASFVKGNLSRAVQVIPKRVDLPWRHVTVAGDAELEAAERLERTTPFTLARGPVIRFLLIEAPQRWRFV VTAHHILIDGWSLPLFMGELLTLYRAGGDVTALPDPPRPYRDYIGWLAGRDEETGRALWRRHLAGVDGPT LLTPALTSSAPTPGRPRLTEVRLDAETTRQLAEAARSRGVTMNTLIQMAWATVLSVITDRTDVSFGVTVS GRPGELAGVERMVGLFINTVPLRVRLDPAAPAGEQCLALQREAAALRDHGYLSHSELRALGGIGELFDTL LVYENFPPGGLVGQARFEANGATFVPSALESLSHFPVTIAAHLADDELTVFVEVIDGALGALRPGDLGRR VLHTAQRLISCWDAPLRSVGVLLPAEHTPAPMVREPLTANSIHDRFAGIAGDRLGSVALTWEAGGDSGTL TYRQLDEAADRMAVALTAAGVGPETSVAVLLSRGPDYVVTMLGVLKAGGVIVPLDPAMPAERISDILEQS RASVVVDDAFVAAVPDVEPPAGYRPAEVTADRAAYIVFTSGTTGRPKGVVGTHGAVLGYAEDHAEQVLRP AAARIGRPLRVGHAWSFTFDAAWQPLAALLDGHSVHLLGEESQRDAEALVYRIGRFGIDMLDTTPSMFAQ LHDVGLLSTVPLAVLALGGEAVSPATWRLIGDECARTGMTAFNCYGPTETTVEAVVAPIDGYQRPSIGQP TRTMRTYVLDAWLRPVPDGVAGELYLSGRQLTRGYLGRAAETAGRFVADPFTPGQRMYRTGDVVRRGADG GLQFLGRADNQVKIRGFRVEPGEIAAVLSGHPAVTDAHVVVDRVGTQTRLIAYVAAATPPAVADLRELMA KRLPRYMVPQRVVVLDELPLTSHGKIDEAALAGIAVEDAPSAAPETPTETALVELMAEVLGDDGIDVEAD FLEMGLDSIVALTLVQAARRRGLEMRARLMLECNTIRELATAIDSGAHDHAPAAVTDDRFGEVMPAPIMS WMYECGNYRRFTQNVLVSLPADITDSRLEQILQALLDRHDMLRAILDERGRLVTRPPGAVRVADVLRVVD AAAHTVLAAEVVAALDRIDPTSGAMVQAVWFRHGPPVLALCVHHLSTDVVSWYLILGALAQIDATLAAGH APDPAAEYTTYREWTRRLYQRSRTEAVERRRGFWVEQLAGSDPLLGRRLPDPRHDTWSTLQSTDVVTDAG ATRAILDRLDGASLEVRDFLLTALTLTLASWRIERGQPAHHGALVALEGHGREDALVGGGVDTSATVGWF TSVYPVRLGAGEAAIDVDTAARNPAAARSLLRAVIQQLAEVPDKGLDYGLLRYTRRDETLRALPEPQVEF NYIGRYDLSADQTSQAWSLITDETLNAHMPAAAEPDLPLRYTFDVISVISGGADGPQLRTSWRWSTALST STEVDRLTALWQQAVTVLGEAL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3844 | - | - | 100% (1493) | amino acid adenylation domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_1000 | - | e-111 | 29.56% (1238) | amino acid adenylation domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_3845 | - | 2e-97 | 28.27% (1383) | amino acid adenylation domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2400c | mbtF | 0.0 | 55.44% (1490) | peptide synthetase MBTF (peptide synthase) |
| M. gilvum PYR-GCK | Mflv_2697 | - | 0.0 | 53.78% (1493) | amino acid adenylation domain-containing protein |
| M. tuberculosis H37Rv | Rv2379c | mbtF | 0.0 | 55.50% (1490) | peptide synthetase MBTF (peptide synthase) |
| M. leprae Br4923 | MLBr_02546 | fadD2 | 2e-27 | 26.46% (495) | acyl-CoA synthetase |
| M. abscessus ATCC 19977 | MAB_2123 | - | 0.0 | 45.25% (1525) | putative peptide synthetase MbtF |
| M. marinum M | MMAR_3690 | mbtF | 0.0 | 44.74% (1531) | non-ribosomal peptide synthetase MbtF |
| M. avium 104 | MAV_2014 | - | 0.0 | 51.65% (1512) | putative sulfotransferase |
| M. smegmatis MC2 155 | MSMEG_4510 | - | 0.0 | 53.75% (1507) | peptide synthetase mbtf |
| M. thermoresistible (build 8) | TH_4360 | - | 0.0 | 57.82% (671) | PUTATIVE amino acid adenylation domain |
| M. ulcerans Agy99 | MUL_3633 | mbtF | 0.0 | 44.55% (1531) | non-ribosomal peptide synthetase MbtF |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4510|M.smegmatis_MC2_155 -----MTATGTPPGIEDVLALSPLQQGLYSLAGLTEEDTG-----ADPYV
TH_4360|M.thermoresistible__bu --------------------------------------------------
Mb2400c|M.bovis_AF2122/97 MGPVAVTRADARGAIDDVMALSPLQQGLFSRATLVAAESGSEAAEADPYV
Rv2379c|M.tuberculosis_H37Rv MGPVAVTRADARGAIDDVMALSPLQQGLFSRATLVAAESGSEAAEADPYV
MAV_2014|M.avium_104 ---MTAAETDVAPDIEDVMALSPLQEGLYSLTTLAEFADGQ--PADDPYV
Mflv_2697|M.gilvum_PYR-GCK ------MTAAKTGAIADVMALSPLQQGLYSLTAMSD--------GDDPYL
Mvan_3844|M.vanbaalenii_PYR-1 --MTQIQQSVEPPVIEDVLALSPLQQGLFSMATLSEGRD------DDPYV
MMAR_3690|M.marinum_M -------MTAAAPQIEDVLALSPLQEGLFALHQLAEDG-------VDLYS
MUL_3633|M.ulcerans_Agy99 -------MTAAAPQIEDVLALTPLQEGLFALHQLAEDG-------VDLYS
MAB_2123|M.abscessus_ATCC_1997 -----MTGTEQQPQIEDVLALSPLQEGFFALSQLADES-------VDLYS
MLBr_02546|M.leprae_Br4923 --------------------------------------------------
MSMEG_4510|M.smegmatis_MC2_155 IAMAADIEGAVDPALLRSCAEAMLVRHPNLRASFFQGNLTRPVAVVPTAV
TH_4360|M.thermoresistible__bu --------------------------------------------------
Mb2400c|M.bovis_AF2122/97 IAMAADAAGPLDIALLRDCAAAMLTRHPNLRASFLHGNLSRPVQVIPSSA
Rv2379c|M.tuberculosis_H37Rv IAMAADAAGPLDIALLRDCAAAMLTRHPNLRASFLHGNLSRPVQVIPSSA
MAV_2014|M.avium_104 IGMAADITGTLDVALLRDCAEKMLVRHPNLRASFFSRGIPRPVQIVPSRV
Mflv_2697|M.gilvum_PYR-GCK IGMSADITGALDVSLLHDCAAAVLARHPNLRAGFFQGDLKRPVQVIPEKV
Mvan_3844|M.vanbaalenii_PYR-1 IAMTADATGDLDARLLRECAAELLDRHANLRASFVKGNLSRAVQVIPKRV
MMAR_3690|M.marinum_M MQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAAFWDRDVPKPVQIVPVHA
MUL_3633|M.ulcerans_Agy99 MQFVVDIDGPVDLELLRRSAQAMLDRHPNLRAAFWDRDVPKPVQIVPVHA
MAB_2123|M.abscessus_ATCC_1997 MQFVADIDGGLDVDLLHRSAQALLTRHPNLRAAFWDRGLPKPVQIVPTHA
MLBr_02546|M.leprae_Br4923 --------------------------------------------------
MSMEG_4510|M.smegmatis_MC2_155 DLPWRHVTAPTAEAAAAIEAEERTRRFDLGRGPLIRFLLIEMPA-QRWRL
TH_4360|M.thermoresistible__bu --------------------------------------------------
Mb2400c|M.bovis_AF2122/97 EVLWRHVRAHPSEVG-ALAAEERRRRFDVGRGPLIRFLLIELPD-ECWHL
Rv2379c|M.tuberculosis_H37Rv EVLWRHVRAHPSEVG-ALAAEERRRRFDVGRGPLIRFLLIELPD-ECWHL
MAV_2014|M.avium_104 ELPWRSVTASPAEVP-MLETAERRRPFDLERGPAIRFLLIELPD-AHWRL
Mflv_2697|M.gilvum_PYR-GCK EVLWRHVRCDGTEVE-PLEREERARRFDLGRGPAMRFLLLETGQ-QRWRF
Mvan_3844|M.vanbaalenii_PYR-1 DLPWRHVTVAGDAELEAAERLERTTPFTLARGPVIRFLLIEAP--QRWRF
MMAR_3690|M.marinum_M ALPWSERVATPAEFD-SIARSERRRPFDLSRGPALRVVVLSVPGETKRRM
MUL_3633|M.ulcerans_Agy99 ALPWSERVATPAEFD-SIARSERRRPFDLSRGPALRVVVLSVPGETKRRM
MAB_2123|M.abscessus_ATCC_1997 DIPWEEREAQPTEFD-EIALRERLRPFNLGKGPAIRLVLLTVPGESRHRM
MLBr_02546|M.leprae_Br4923 --------------------------------------------------
MSMEG_4510|M.smegmatis_MC2_155 VVTAHHIAIDGWSLPVFVGEYITLYAADGDTAVFPAAPRPYRDYIGWLAG
TH_4360|M.thermoresistible__bu --------------------------------------------------
Mb2400c|M.bovis_AF2122/97 VIVAHHIVIDGWSLPLFVSELLALYRAGGHVAALPAAPRPYRDYIGWLAG
Rv2379c|M.tuberculosis_H37Rv VIVAHHIVIDGWSLPLFVSELLALYRAGGHVAALPAAPRPYRDYIGWLAG
MAV_2014|M.avium_104 VLTAHHIVIDGWSLPVFVNELMTLYRAGGDRSALPAAPRPYRDYIGWLAG
Mflv_2697|M.gilvum_PYR-GCK VITAHHIVIDGWSLSLLVSELLALYRAAGNTSALPDAPRPYRDYIGWLAA
Mvan_3844|M.vanbaalenii_PYR-1 VVTAHHILIDGWSLPLFMGELLTLYRAGGDVTALPDPPRPYRDYIGWLAG
MMAR_3690|M.marinum_M IFTAHHILVDGWSLAVFFTELLAVYRAGGAADALP-AARPYRDYIVWLAK
MUL_3633|M.ulcerans_Agy99 IFTAHHILVDGWSLAVFFTELLAVYRAGGAADALP-AARPYRDYIVWLAN
MAB_2123|M.abscessus_ATCC_1997 IVTSHHILMDGWAIAIFFSELLAVYQAGGSLAGLP-AVRPYRDYIAWLNA
MLBr_02546|M.leprae_Br4923 --------------------------------------------------
MSMEG_4510|M.smegmatis_MC2_155 RDHDASRARWRAHLDGLDGPTLLAPALSGREAEPG----LPARTEVTLDE
TH_4360|M.thermoresistible__bu --------------------------------------------------
Mb2400c|M.bovis_AF2122/97 RDQTASRAMWADHLNGLDGPTLLSPALADTPVQPG----IPGRTEVRLDR
Rv2379c|M.tuberculosis_H37Rv RDQTASRAMWADHLNGLDGPTLLSPALADTPVQPG----IPGRTEVRLDR
MAV_2014|M.avium_104 RDLQASQRVWREHLAGLPGPTLLAASLGSAEATGGQRTALPRTTELRMPA
Mflv_2697|M.gilvum_PYR-GCK RDQDHARSLWRAHLADLDGPTLLAPALGAATIGDG----LPGMVELTADP
Mvan_3844|M.vanbaalenii_PYR-1 RDEETGRALWRRHLAGVDGPTLLTPALTSSAPTPG----RPRLTEVRLDA
MMAR_3690|M.marinum_M QDRSAALAGWMDYLRGVSEP--LMVAYEATAGQS-----KPGKTELLLPA
MUL_3633|M.ulcerans_Agy99 QDRSAALAGWMDYLRGVSEP--LMVAYEATAGQS-----KPGKTELLLPA
MAB_2123|M.abscessus_ATCC_1997 QDTTEATARWTRYLGTVSGP--LMLADGAVAAHDN----VPEKSQFLLAP
MLBr_02546|M.leprae_Br4923 --------------------------------------------------
MSMEG_4510|M.smegmatis_MC2_155 QASAEIFDGARARGVTVNTLFQMAWAAILSAFTDRTDVVYGVTVSGRPDE
TH_4360|M.thermoresistible__bu --------------------------------------------------
Mb2400c|M.bovis_AF2122/97 EATAELADAARTRGVTISTLVQMAWATTLSAFTGRGDVTFGVTVSGRPSE
Rv2379c|M.tuberculosis_H37Rv EATAELADAARTRGVTISTLVQMAWATTLSAFTGRGDVTFGVTVSGRPSE
MAV_2014|M.avium_104 EATARLAAETRSRGITVNTLMQMAWALVLSRLTDTRDVVFGVTVSGRPPE
Mflv_2697|M.gilvum_PYR-GCK SITEAVVDAARARGVTVNSLVQLAWALTLSSLTDRDDITFGVTVSGRPDD
Mvan_3844|M.vanbaalenii_PYR-1 ETTRQLAEAARSRGVTMNTLIQMAWATVLSVITDRTDVSFGVTVSGRPGE
MMAR_3690|M.marinum_M ADTARLRQWAGRHGLTLNTAVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQ
MUL_3633|M.ulcerans_Agy99 ADTARLRQWAGRHGLTLNTTVLFAWAVVLSRLTDRRDVVFGTVVSGRPDQ
MAB_2123|M.abscessus_ATCC_1997 EETARLRQWAAANGLTLNTVTAFAWALVLGRLTDRTDVVFGTIVSGRPKE
MLBr_02546|M.leprae_Br4923 -------------------------MTKLRHYLERGAAEVHYLRSIFESG
MSMEG_4510|M.smegmatis_MC2_155 LSGVESMVGLFINTVPLRIRLDPAGSVGEQCLAVQREAADLRDHSYLSHT
TH_4360|M.thermoresistible__bu --------------------------------------------------
Mb2400c|M.bovis_AF2122/97 LSGVETMIGLFINTVPLRVRLDARATVGGQCAVLQRQFAMLRDHSYLGFN
Rv2379c|M.tuberculosis_H37Rv LSGVETMIGLFINTVPLRVRLDARATVGGQCAVLQRQFAMLRDHSYLGFN
MAV_2014|M.avium_104 LTGVETMVGLFINTVPLRVRLDPAATVGEQCRAVQRDAALLREHSYLGHA
Mflv_2697|M.gilvum_PYR-GCK LAGVESMIGLFVNTVPLRVRLDPALTAGAQCRALQQDAATLRDHSYLGHA
Mvan_3844|M.vanbaalenii_PYR-1 LAGVERMVGLFINTVPLRVRLDPAAPAGEQCLALQREAAALRDHGYLSHS
MMAR_3690|M.marinum_M LPGVETMVGLFINAVPVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLS
MUL_3633|M.ulcerans_Agy99 LLGVETMVGLFINAVPVVHYVSGTEAVVAQCTQVQRQSSAMRDVSYLSLS
MAB_2123|M.abscessus_ATCC_1997 LPDVERMVGLFINSVPMVHHIDYSASVVEQCVQLQREAAAMRDIGYLSLS
MLBr_02546|M.leprae_Br4923 ALGFEPPLTYAAMAVAMRKWGDLAMLPAMPARRSPHRAALIDEEGTLTYK
MSMEG_4510|M.smegmatis_MC2_155 EIRALGGIGELFDTLLVYENFPPGGLVGSDEFPLGSDGDGAVLRPSALES
TH_4360|M.thermoresistible__bu --------------------------------------------------
Mb2400c|M.bovis_AF2122/97 EFRAIAGIGEMFDTLLVYENFPPGEVVGTAEFVAN----GVTFRPVALES
Rv2379c|M.tuberculosis_H37Rv EFRAIAGIGEMFDTLLVYENFPPGEVVGTAEFVAN----GVTFRPVALES
MAV_2014|M.avium_104 QLRALGGIGEMFDTLLVYENFPMDGLTAGGELSAG----GATFRPSALQT
Mflv_2697|M.gilvum_PYR-GCK ELRALAGVGELFDTLLVYENFPPGAVAGAGTLEAA----GATFTPVALQS
Mvan_3844|M.vanbaalenii_PYR-1 ELRALGGIGELFDTLLVYENFPPGGLVGQARFEAN----GATFVPSALES
MMAR_3690|M.marinum_M EIQREHGRGPLFDSLFVFENAPIDDAIRPATTPDG-----AQFLPVEMES
MUL_3633|M.ulcerans_Agy99 EIQREHGRGPLFDSLFVFENAPIDDAIRPATTPDG-----AQFLPVEMES
MAB_2123|M.abscessus_ATCC_1997 TLQRAEGSAALFDTLFVFENAPIGDVVQEVEMADG-----ARFRPVEMES
MLBr_02546|M.leprae_Br4923 ELDR------------------------------------------AAHA
MSMEG_4510|M.smegmatis_MC2_155 LSHFPVTIAAHPTHGRLTVLVETLDGALGMLDPHALGRRVLTVVQRLLRS
TH_4360|M.thermoresistible__bu --------------------------------------------------
Mb2400c|M.bovis_AF2122/97 LSHFPVTVAAHRSTGELTLLVEVLDGALGTMAPESLGRRVLAVLQRLVSR
Rv2379c|M.tuberculosis_H37Rv LSHFPVTVAAHRSTGELTLLVEVLDGALGTMAPESLGRRVLAVLQRLVSR
MAV_2014|M.avium_104 LSHFPIAVAAHMEGGELVVLIEVVDGALGVIPADAVGRRLLTTAERLLRH
Mflv_2697|M.gilvum_PYR-GCK LAHFPVTIAAHLTDGRLTVLVEAKDGALGQITPRALGTRLLATVSRIVEG
Mvan_3844|M.vanbaalenii_PYR-1 LSHFPVTIAAHLADDELTVFVEVIDGALGALRPGDLGRRVLHTAQRLISC
MMAR_3690|M.marinum_M LTHYPLTVVSHLREDELLVLIEAIAEALPYLPAAEIGERMLTVLRQLPDI
MUL_3633|M.ulcerans_Agy99 LTHYPLTVVSHLREDELLVLIEAIAEALPYLPAAEIGERMLTVLRQLPDI
MAB_2123|M.abscessus_ATCC_1997 LAHYPLTVVSHMHGDSLLVLIEAIPQALPHVSGASVGERLVSVLRQLPDI
MLBr_02546|M.leprae_Br4923 LANGLIAKGVRGGDGIAILARNHRWFVIANYGCARVGARIILLNSEFS--
MSMEG_4510|M.smegmatis_MC2_155 WDRPVRDVAVTLDDEVATVAP--TDTAVRPGG-FHTAFTEAAAQRLGSIA
TH_4360|M.thermoresistible__bu --------------------------------------------------
Mb2400c|M.bovis_AF2122/97 WDRPLRDVDILLDGEHDPTAPGLPDVTTSAPA-VHTRFAEIAAAQPDSVA
Rv2379c|M.tuberculosis_H37Rv WDRPLRDVDILLDGEHDPTAPGLPDVTTSAPA-VHTRFAEIAAAQPDSVA
MAV_2014|M.avium_104 WERPLRAVSVLFDDEAAPLRAAGPIAPPSPKC-LPARFADVVAQTPDAPA
Mflv_2697|M.gilvum_PYR-GCK WDRPLREISISPDDHPVPVPVSEAAPTPSPSTGVHTRFTETASARLGSVA
Mvan_3844|M.vanbaalenii_PYR-1 WDAPLRSVGVLLPAEHTPAPMVREPLT---ANSIHDRFAGIAGDRLGSVA
MMAR_3690|M.marinum_M GDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQATPDAVA
MUL_3633|M.ulcerans_Agy99 GDGTPDDLDIRTAAELKAHGLLAARSAPTFDTTVWEMFERQVQTTPDAVA
MAB_2123|M.abscessus_ATCC_1997 GGGTPDALELLTARER-AEIVVTASAADPSVVSVWDLFEREAQAHPESLA
MLBr_02546|M.leprae_Br4923 -----------------------------------GPQIKEVSEREGAKV
MSMEG_4510|M.smegmatis_MC2_155 LTWDGG----ELTYRQLDEAADRVAAELRRRGVGTETPVPIRLPRGPEYV
TH_4360|M.thermoresistible__bu -------------------------------------------------V
Mb2400c|M.bovis_AF2122/97 VSWADG----QLTYRELDALADRLATGLRRADVSRETPVAVALSRGPRYV
Rv2379c|M.tuberculosis_H37Rv VSWADG----QLTYRELDALADRLATGLRRADVSRETPVAVALSRGPRYV
MAV_2014|M.avium_104 VSWAQG----SLTYRELDEATNRLAAQLVALGVEPETPVAIKLSRGPRYV
Mflv_2697|M.gilvum_PYR-GCK LSWDGG----ALTYRQLDEAADRLAAVLTASGVRTETPVAVRLRRGADYV
Mvan_3844|M.vanbaalenii_PYR-1 LTWEAGGDSGTLTYRQLDEAADRMAVALTAAGVGPETSVAVLLSRGPDYV
MMAR_3690|M.marinum_M LTAAAG---VRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSI
MUL_3633|M.ulcerans_Agy99 LAAAGG---VRHTYAELHARACRLAGELAEHGVGPETVVALVLPRSERSI
MAB_2123|M.abscessus_ATCC_1997 LVADAG---TRYTYAQLRGAVSRLCAELIESGVTPETTVALALPRSADSI
MLBr_02546|M.leprae_Br4923 IIYDDE-------YTKVVSKAEPALGKLRALGVNPDE-------------
MSMEG_4510|M.smegmatis_MC2_155 VAMLGVLKAGGLIVPLDPAMPDERVDEIIRQTHPDGRQPAIVDDAFVAAV
TH_4360|M.thermoresistible__bu IAMLAILKAGGVIVPLDPSMPGHRIAEILRQTS----APIVVDQAVSDAV
Mb2400c|M.bovis_AF2122/97 AAMLAVLKAGGMIVPLDPAMPGERVAEILRQTS----APVVIDEGVFAAS
Rv2379c|M.tuberculosis_H37Rv AAMLAVLKAGGMIVPLDPAMPGERVAEILRQTS----APVVIDEGVFAAS
MAV_2014|M.avium_104 VAMLAVLKAGGMCVPMEPGMPAPRVNSILRQSG----ASIVLDEERIDEL
Mflv_2697|M.gilvum_PYR-GCK VAMFAVLKAGGAIVPLDPAMPADRIEVILRRAG----VTVVVDEDTVARA
Mvan_3844|M.vanbaalenii_PYR-1 VTMLGVLKAGGVIVPLDPAMPAERISDILEQSR----ASVVVDDAFVAAV
MMAR_3690|M.marinum_M VAILGVLAAGGAYLPVDVTLPSARVESIVRQAS----PALAITEADYSQL
MUL_3633|M.ulcerans_Agy99 VAILGVLAAGGAYLPVDVTLPSARVESIVRQAS----PALAITEADYSQL
MAB_2123|M.abscessus_ATCC_1997 IAILAVLAAGAAYVPVDIGLPAARVESILRQSN----PTLVITVDRHRDI
MLBr_02546|M.leprae_Br4923 --------------EEPPGSTDETLAELIARSS---------SAP-----
. : :: ::
MSMEG_4510|M.smegmatis_MC2_155 RAADAELPADYRP---------------AHVHPGQGAYIVFTSGTTGKPK
TH_4360|M.thermoresistible__bu RAS----SAAWSP---------------PPVHPGQAAYTVFTSGTTGVPK
Mb2400c|M.bovis_AF2122/97 VGAD--ILEDDRA---------------ITVPVDQAAYVIFTSGTTGTPK
Rv2379c|M.tuberculosis_H37Rv VGAD--ILEEDRA---------------ITVPVDQAAYVIFTSGTTGTPK
MAV_2014|M.avium_104 LEAGRSQHGGFEP---------------PDIPPAQAAYVVFTSGTTGEPK
Mflv_2697|M.gilvum_PYR-GCK TAEP---PAQYRP---------------AETLPGQAAYVVFTSGTTGEPK
Mvan_3844|M.vanbaalenii_PYR-1 PDVEP--PAGYRP---------------AEVTADRAAYIVFTSGTTGRPK
MMAR_3690|M.marinum_M VGTAVPTLALDDPAAVESISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPK
MUL_3633|M.ulcerans_Agy99 VGTAVPTLALDDPAAVDSISRRSAAAPTVDRRPEQSAYVIFTSGSTGEPK
MAB_2123|M.abscessus_ATCC_1997 AGRGYQVLILDDPETAARISGRSESGHAVVVHRDQSAYLIFTSGSTGEPK
MLBr_02546|M.leprae_Br4923 ----------------------------APKVRKRASIIILTSGTTGTPK
:.: ::***:** **
MSMEG_4510|M.smegmatis_MC2_155 GVIGTHQALLAYAADHARNVLRPAAQRVGHPLRVAHAWSFTFDAAWQPLV
TH_4360|M.thermoresistible__bu GVVGTHDALLAYADDHARNVLRPAAARLGRPLRIAHAWSFTFDAAWQPLA
Mb2400c|M.bovis_AF2122/97 GVIGTHRALSAYADDHIERVLRPAAQRLGRPLRIAHAWSFTFDAAWQPLV
Rv2379c|M.tuberculosis_H37Rv GVIGTHRALSAYADDHIERVLRPAAQRLGRPLRIAHAWSFTFDAAWQPLV
MAV_2014|M.avium_104 GVIGTHGAVGAYADDHLDRVLRPAAAALGRPLRIAHAWSFAFDAAWQPLV
Mflv_2697|M.gilvum_PYR-GCK GVIGTHRALLAYADDHIGAILRPAADRVGRPLRIAHAWSFTFDAAWQPLA
Mvan_3844|M.vanbaalenii_PYR-1 GVVGTHGAVLGYAEDHAEQVLRPAAARIGRPLRVGHAWSFTFDAAWQPLA
MMAR_3690|M.marinum_M GVVGTNAAVLSYFADHAERVYRAARARLGRPLRIAHAWSLSFDASWQPMV
MUL_3633|M.ulcerans_Agy99 GVAGTNAAVLSYFADHAERVYRAARARLGRPLRIAHAWSLSFDASWQPMV
MAB_2123|M.abscessus_ATCC_1997 GVVGTHAALMSYFADHRDRVYRPATARLGRKLRIAHAWSLSFDASWQPMI
MLBr_02546|M.leprae_Br4923 GANRNTPASLAPLGGILSKVPFRAHEVTLLPAPMFHALGY-----LHATL
*. . * . . : * : ** . :.
MSMEG_4510|M.smegmatis_MC2_155 ALLDGHANHIVGDDVQRDAEALVETIGRHAIDMIDTTPSMFTQLRA--AG
TH_4360|M.thermoresistible__bu ALFEGHAVHIIGDDVQRDAEALVDTIDRHRVDMIDITPSMFEQLRA--FG
Mb2400c|M.bovis_AF2122/97 ALLDGHAVHIVDDHRQRDAGALVEAIDRFGLDMIDTTPSMFAQLHN--AG
Rv2379c|M.tuberculosis_H37Rv ALLDGHAVHIVDDHRQRDAGALVEAIDRFGLDMIDTTPSMFAQLHN--AG
MAV_2014|M.avium_104 ALLDGHGVHVVDEATQTDAEALVALIAEHGVDMIDTTPSMFAQLQA--FG
Mflv_2697|M.gilvum_PYR-GCK ALLDGHSVHIVDDATQRDAEALVDTIARFGVDMIDTTPSMFARLRD--VG
Mvan_3844|M.vanbaalenii_PYR-1 ALLDGHSVHLLGEESQRDAEALVYRIGRFGIDMLDTTPSMFAQLHD--VG
MMAR_3690|M.marinum_M GLLDGHEIHLFDAEEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSA--AG
MUL_3633|M.ulcerans_Agy99 GLLDGHEIHLFDADEMRDADRLVEGIAIGQIDMIDTTPSMFVQLSA--AG
MAB_2123|M.abscessus_ATCC_1997 GLLDGHAVHLFDAEAMRDASLLVRGMAERGVDMIDTTPSMLAQLSA--AG
MLBr_02546|M.leprae_Br4923 AMFLGSTLVLR---RRFKPATVLEDIEKHQATAMVVVPVMLSRILDTLEN
.:: * : .. :: : : .* *: :: .
MSMEG_4510|M.smegmatis_MC2_155 LLSTVPLAVLALGGEAIDTALWQAIQAECERTWMSAHNCYGPTEATVEAV
TH_4360|M.thermoresistible__bu LLGRVPLAVLALGGEAVGIGTWRFIRDECERTGMAAYNCYGPTETTVEAV
Mb2400c|M.bovis_AF2122/97 LLDRAPLAVLALGGEALGAATWRMIQQNCARTAMTAFNCYGPTETTVEAV
Rv2379c|M.tuberculosis_H37Rv LLDRAPLAVLALGGEALGAATWRMIQQNCARTAMTAFNCYGPTETTVEAV
MAV_2014|M.avium_104 LLSEAPLTVLALGGEALGNAAWARIRNACNTTTMSAYNCYGPTETTVEAV
Mflv_2697|M.gilvum_PYR-GCK LLSTVPLAVLALGGEAVDPGLWQQIRQECARTGMSAFNCYGPTETTVEAV
Mvan_3844|M.vanbaalenii_PYR-1 LLSTVPLAVLALGGEAVSPATWRLIGDECARTGMTAFNCYGPTETTVEAV
MMAR_3690|M.marinum_M LLDHN-LSVLALGGEAINTGLWDQLR---GLSQMAVYNCYGPTEMTVEAV
MUL_3633|M.ulcerans_Agy99 LLDHN-LSVLALGGEAINTGLWDQLR---GLSQMAVYNCYGPTEMTVEAV
MAB_2123|M.abscessus_ATCC_1997 LLDHE-LAVLALGGEAIETALWDRLR---SLSDTAVYNCYGPTETTVEAV
MLBr_02546|M.leprae_Br4923 LETKSDLSSLRVVFVSGSQLGAELATRALEELGPVIYNMYGSTEIAFATI
* *: * : : .* **.** :. ::
MSMEG_4510|M.smegmatis_MC2_155 VAAIADHR-DPCIGKPTDPTAAYVLDSWLRPVPAGVAGELYLAGGQLTRG
TH_4360|M.thermoresistible__bu VGRFAAHE-QPVIGLPTRHTRAYVLDAWLRPVPDGVAGELYLAGAQLTRG
Mb2400c|M.bovis_AF2122/97 VAAVAEHA-RPVIGRPTCTTRAYVMDSWLRPVPDGVAGELYLAGAQLTRG
Rv2379c|M.tuberculosis_H37Rv VAAVAEHA-RPVIGRPTCTTRAYVMDSWLRPVPDGVAGELYLAGAQLTRG
MAV_2014|M.avium_104 VAAIAEHA-EPSIGRPTRHTRGYVLDSELRPVPCGATGELYLGGAQLARG
Mflv_2697|M.gilvum_PYR-GCK VAEIGAHE-RPTIGRPTAPTRAYVLDSWLRPVPSGAAGELYLAGGQLTRG
Mvan_3844|M.vanbaalenii_PYR-1 VAPIDGYQ-RPSIGQPTRTMRTYVLDAWLRPVPDGVAGELYLSGRQLTRG
MMAR_3690|M.marinum_M VAAVKDYR-KPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARG
MUL_3633|M.ulcerans_Agy99 VAAVKDYR-KPTIGTANAGTFGYVFDSALRMVPDGVVGELYLSGAQLARG
MAB_2123|M.abscessus_ATCC_1997 VAAVKEYP-APTIGTPNQGMVGYVLDSRLRPVPDGAVGELYLAGAQLARG
MLBr_02546|M.leprae_Br4923 AGPKDLQINSATVGPVVKGVKVKILDDSGKEVPRGQVGRIFVGNAFPFEG
.. . :* ::* : ** * .*.:::.. .*
MSMEG_4510|M.smegmatis_MC2_155 YVGRPGETAARFVADPFTLGARMYRTGDVVRRTPDGALQFLGRSDDQVKI
TH_4360|M.thermoresistible__bu YLGRAGETATRFVPDPFDPGRRMYRTGDVVRRTADGALQYLGRSDDQVKI
Mb2400c|M.bovis_AF2122/97 YLGRPAETAARFVAEPNGRGSRMYRTGDVVRRLPDGGLEFLGRSDDQVKI
Rv2379c|M.tuberculosis_H37Rv YLGRPAETAARFVAEPNGRGSRMYRTGDVVRRLPDGGLEFLGRSDDQVKI
MAV_2014|M.avium_104 YLGRAGETASRFVADPFAASERMYRTGDLVRRLPDGSLQYVGRADAQVKI
Mflv_2697|M.gilvum_PYR-GCK YLGRPGETAARFVPDPFVPGARMYRTGDVVRRAVDGTLAFLGRSDTQVKI
Mvan_3844|M.vanbaalenii_PYR-1 YLGRAAETAGRFVADPFTPGQRMYRTGDVVRRGADGGLQFLGRADNQVKI
MMAR_3690|M.marinum_M YVGRPGMTAARFVADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKI
MUL_3633|M.ulcerans_Agy99 YVGRPGMTAARFVADPLRPGQRMYRTGDLVRRLSHGGYAYVGRADTQVKI
MAB_2123|M.abscessus_ATCC_1997 YAGKPAVTAAAFVADPRRAGQRMYRTGDLVRRLPHGGFAYLGRADSQVKI
MLBr_02546|M.leprae_Br4923 YTGGGG----KQIIDG------LLSSGDVGYFDEHDLLYISGRDDEMIVS
* * . : : : :**: .. ** * :
MSMEG_4510|M.smegmatis_MC2_155 RGFRVEPGEVAAALHRHPQVRHAHVA-LRRHRSGPRLVAYVVTDASLADA
TH_4360|M.thermoresistible__bu RGFRVEPGEVAAVLQTHPAVRAAHVA-VRRHRSGPRLVGYVATGGAEVDV
Mb2400c|M.bovis_AF2122/97 RGFRVEPGEIAAVLNGHHAVHGCHVT-ARGHASGPRLTAYVAGGPQPPPV
Rv2379c|M.tuberculosis_H37Rv RGFRVEPGEIAAVLNGHHAVHGCHVT-ARGHASGPRLTAYVAGGPQPPPV
MAV_2014|M.avium_104 RGHRVEPGEIAAALESHPAVRHAGVL-VRHRDGAPRLTGYVATHEAAPDT
Mflv_2697|M.gilvum_PYR-GCK RGFRVEPGEVAAVLRTHPAVGQAYVA-VRPHRDGHRLTAYVTG---EPQL
Mvan_3844|M.vanbaalenii_PYR-1 RGFRVEPGEIAAVLSGHPAVTDAHVV-VDRVGTQTRLIAYVAAATPPAVA
MMAR_3690|M.marinum_M RGYRVEVGEIEAALRGQPGVHDAAVS-VLRQQDRTSLVGFVVWQDNMHED
MUL_3633|M.ulcerans_Agy99 RGYRVEVGEIEAALRGQPGVHDAAVS-VLRQQDRTSLVGFVVWQDNMHED
MAB_2123|M.abscessus_ATCC_1997 RGYRVEVGEIESALRLQPDIQTAAVT-VVRRAGGASLVGFVVCEKDTFDS
MLBr_02546|M.leprae_Br4923 GGENVFPAEVEDLISGHPEVVEATAIGVDDKEWGARLRAFVVKKQDATID
* .* .*: : : : . . * .:*.
MSMEG_4510|M.smegmatis_MC2_155 AG--ELRRMLAATLPRYLVPHHILLVDEIPLTTNGKVDDARLAALDSG--
TH_4360|M.thermoresistible__bu D---ELRRMLVARLPRYLVPHRVTVLDQLPLTPHGKIDDAALAAHDDA--
Mb2400c|M.bovis_AF2122/97 A---ELRAMLLERLPRYLVPHHIVVLDELPLTPHGKIDENALAAIN----
Rv2379c|M.tuberculosis_H37Rv A---ELRAMLLERLPRYLVPHHIVVLDELPLTPHGKIDENALAAIN----
MAV_2014|M.avium_104 PSPAELRGMLSARLPRYMVPQRIIMVDEIPLTPNGKLDETALAAVDNA--
Mflv_2697|M.gilvum_PYR-GCK R---ELRAWLGRRLPRYLMPNAIVAVDRIPLTAHGKIDEPALVALEP---
Mvan_3844|M.vanbaalenii_PYR-1 D----LRELMAKRLPRYMVPQRVVVLDELPLTSHGKIDEAALAGIA----
MMAR_3690|M.marinum_M LI--KLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLAEDAL
MUL_3633|M.ulcerans_Agy99 LI--KLRAGLTERLPSYMVPARIVTLPRLPVNANGKLDGHALDRLAEDAL
MAB_2123|M.abscessus_ATCC_1997 AR--TMMR-LADRLPSYMMPSRLVPLPQLPVTVNGKLDGGALERLAREAL
MLBr_02546|M.leprae_Br4923 ED--AIKAYVRDHLARYKVPREVIFLEELPRNPTGKVLKRELRDFEVH--
: : *. * :* : : .:* . **: *
MSMEG_4510|M.smegmatis_MC2_155 --RQSGGFQGPATDTERVVAEVLAEVLDTRAVDVTAEFLDLGLDSIVALT
TH_4360|M.thermoresistible__bu --TGSP-VAEPETPTEKALVEAVVDLLGPTPVDVDAELLSLGVDSIVALS
Mb2400c|M.bovis_AF2122/97 --VTEGPATPPQTPTELVLAEAFADVMETSNVDVTAGFLQMGLDSIVALS
Rv2379c|M.tuberculosis_H37Rv --VTEGPATPPQTPTELVLAEAFADVMETSNVDVTAGFLQMGLDSIVALS
MAV_2014|M.avium_104 --EAVDGAATPQTGTESALAELIAELLGQPRVDVTADFLALGLDSIMALS
Mflv_2697|M.gilvum_PYR-GCK --AADGAATRPQTPTEVELAAVLAEVLGVGEIDVTADFLELGLDSIVALS
Mvan_3844|M.vanbaalenii_PYR-1 --VEDAPSAAPETPTETALVELMAEVLGDDGIDVEADFLEMGLDSIVALT
MMAR_3690|M.marinum_M TSVSGGTAVSASTDTERVLCELFEEQLN-AVPHIDDDLFLFGMDSIVAIS
MUL_3633|M.ulcerans_Agy99 TSVSGGTAVSASTDTERVLCELFEEQLN-AVPHIDDDLFLFGMDSIVAIS
MAB_2123|M.abscessus_ATCC_1997 SGGAVGEQAQPATATECVLCECCAELFDGTAPGIDEDFFSLGVDSIVAIS
MLBr_02546|M.leprae_Br4923 --------------------------------------------------
MSMEG_4510|M.smegmatis_MC2_155 VVQAVRRRGLALRARLMLECANVRELAAAIDADAHHAAVDHTPEDSG--P
TH_4360|M.thermoresistible__bu VVQAARRRGLALRARLMLECGSIRELAAAIDAEANAAPDTESADAGAGEP
Mb2400c|M.bovis_AF2122/97 VVQAARRRGIALRARLMVECDTIRELAAAIDSDAAWQAPAN----DAGEP
Rv2379c|M.tuberculosis_H37Rv VVQAARRRGIALRARLMVECDTIRELAAAIDSDAAWQAPAN----DAGEP
MAV_2014|M.avium_104 VVQAARARGIALRARLVLDCTSIRELAEAIDAESTPAAGEVD---DGTGP
Mflv_2697|M.gilvum_PYR-GCK VVQTARRRGVVMRAKLMLDCATVRELAAAIDDAGSGPPSAD----EGSGP
Mvan_3844|M.vanbaalenii_PYR-1 LVQAARRRGLEMRARLMLECNTIRELATAIDSGAHDHAPAAVT-DDRFGE
MMAR_3690|M.marinum_M LVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPAD---ADYGA
MUL_3633|M.ulcerans_Agy99 LVHKARRQGLRVDPRMVLTATTIRQLGAAIDAAVDSQDAPAD---ADYGA
MAB_2123|M.abscessus_ATCC_1997 LVNKARKRDLVITPRMVLAAPTIRQLAALVDTRGHVDSLAGE---ADYGE
MLBr_02546|M.leprae_Br4923 --------------------------------------------------
MSMEG_4510|M.smegmatis_MC2_155 IPLLPNGSWLYQYGEPRRLAQTEAFRLPEGTTAAQLRTLLRTVVDGHEVL
TH_4360|M.thermoresistible__bu IPVLPAVHWLYQHGDPRRLAQTEAIRLPDGITGADLRTLLTTVVASHEVL
Mb2400c|M.bovis_AF2122/97 IPVLPNTHWLYEYGDPRRLAQTEVIRLPDRITRERLDAVLAAVVDGHEVL
Rv2379c|M.tuberculosis_H37Rv IPVLPNTHWLYEYGDPRRLAQTEVIRLPDRITRERLDAVLAAVVDGHEVL
MAV_2014|M.avium_104 MPLLPNGRWLYEHGQPRRLAQTEAIRVPQTLRRDQLETALAGIIDGHEVL
Mflv_2697|M.gilvum_PYR-GCK IALLPNAHWLYEFGDPRRLASTEALRLPRGITGPQIRALLQSVVDAHPVL
Mvan_3844|M.vanbaalenii_PYR-1 VMPAPIMSWMYECGNYRRFTQNVLVSLPADITDSRLEQILQALLDRHDML
MMAR_3690|M.marinum_M VRPLPMVSWLYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTL
MUL_3633|M.ulcerans_Agy99 VLPLPMVSWLYEYGNYRRFTHTVLLRLPSGIDRSSIELMLQLLLDGHDTL
MAB_2123|M.abscessus_ATCC_1997 VPPLPVVSWMYESEIYRRLSLSVLVRLPAGIDRPGIERMLQLLLDGFTML
MLBr_02546|M.leprae_Br4923 --------------------------------------------------
MSMEG_4510|M.smegmatis_MC2_155 RTRLDR--VTRTLVPHGP---RDVLTEAVGV------GTLADAVAEQAAL
TH_4360|M.thermoresistible__bu RTRLDR--TTMTLVPQHDGDIGDRLREVTVR------GDLTAAVAEQVDL
Mb2400c|M.bovis_AF2122/97 RCRFDR--DAMALVAQPK---TDILSEVWVS------GELVTAVAEQTLG
Rv2379c|M.tuberculosis_H37Rv RCRFDR--DAMALVAQPK---TDILSEVWVS------GELVTAVAEQTLG
MAV_2014|M.avium_104 RSRVDR--ATMTLVPGPAPDIGKELEEVAVV------GDLRAAVADRAAR
Mflv_2697|M.gilvum_PYR-GCK RTRLDR--AAMTLVDGGF---DLPLTEIEVG------DEGSAAVARHAAA
Mvan_3844|M.vanbaalenii_PYR-1 RAILD---ERGRLVTRPPGAVRVADVLRVVD------AAAHTVLAAEVVA
MMAR_3690|M.marinum_M RSILTETPEGPRLVTREPAAVRAEDVLTRITLPEGSDDELASAVAHAARV
MUL_3633|M.ulcerans_Agy99 RSILTETPEGPRLVTREPAAVRAEDVLTRIRLPEGSDDELASAVAHAARV
MAB_2123|M.abscessus_ATCC_1997 RSTLVDTPDGARVVTREPGVVRGESVLSRVELPTG--ESAHAAITNAARQ
MLBr_02546|M.leprae_Br4923 --------------------------------------------------
MSMEG_4510|M.smegmatis_MC2_155 SVDRIDPQQGSMLDAVWLR---HPDAPGGVFILTAHVLALDPASWRIVVG
TH_4360|M.thermoresistible__bu SVRTLDPEGGRLWSAVWLR---PEQGPG-VLVWTAHVIAMDPASWRVVLG
Mb2400c|M.bovis_AF2122/97 VLASLDPQAGRLLSAVWLR---EPDGPG-VLVLTAHVLAMDPASWRIVLG
Rv2379c|M.tuberculosis_H37Rv ALASLDPQAGRLLSAVWLR---EPDGPG-VLVLTAHVLAMDPASWRIVLG
MAV_2014|M.avium_104 AIDRLDPERGVLLGAVWLR---PADGDG-VLLLTAHVIALDPASWRVVLG
Mflv_2697|M.gilvum_PYR-GCK ALEHLDPQRGPLWGAVWLRGSDDADSTSSVLLLTAHVLAMDPVSWQIVIG
Mvan_3844|M.vanbaalenii_PYR-1 ALDRIDPTSGAMVQAVWFR-----HGPP-VLALCVHHLSTDVVSWYLILG
MMAR_3690|M.marinum_M VTDQIDPSAGAMVRAIWFRGTEHRADPANILLLTAHHLAVDVVSWHIMLG
MUL_3633|M.ulcerans_Agy99 VTDQIDPSAGAMVRAIWFRGTEHRADPANMLLLTAHHLAVDVVSWHIMLG
MAB_2123|M.abscessus_ATCC_1997 AFDSLDPRSGAMMRAVWLAS----RDSGDVLLLTVHHLAMDVVSWHIVLG
MLBr_02546|M.leprae_Br4923 --------------------------------------------------
MSMEG_4510|M.smegmatis_MC2_155 ELETAWHALASGREPTPVREHTSLRRWSRMLSERALKLDT---VDFWHRQ
TH_4360|M.thermoresistible__bu DLDAGWHALSAGRPS-----------------------------------
Mb2400c|M.bovis_AF2122/97 ELDAGLHALAAGRAPSPARENTSYRQWSRLLAQRAKALDS---VDFWVAE
Rv2379c|M.tuberculosis_H37Rv ELDAGLHALAAGRAPSPARENTSYRQWSRLLAQRAKALDS---VDFWVAE
MAV_2014|M.avium_104 ELGAALTAAATGHSPAAVREHTSYRRWAHALTARAHRLDT---VGFWASE
Mflv_2697|M.gilvum_PYR-GCK ELDAGWHALAGGRAPAALGEHTGYRQWSNLLRERAESSDG---LQFWLDQ
Mvan_3844|M.vanbaalenii_PYR-1 ALAQIDATLAAGHAPDPAAEYTTYREWTRRLYQRSRTEAVERRRGFWVEQ
MMAR_3690|M.marinum_M DLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYWAAL
MUL_3633|M.ulcerans_Agy99 DLAAAWRSLQAGTPPKILPEFTSYRRWCELMWHRASAPQVQDQRDYWAAL
MAB_2123|M.abscessus_ATCC_1997 YLADAWIAVRSGTAPKAPMEFTSYRQWSQLMHQRASSHDVLRQRDYWAEQ
MLBr_02546|M.leprae_Br4923 --------------------------------------------------
MSMEG_4510|M.smegmatis_MC2_155 FDGADPDIGARRVDPATDRMRDIAVEMTFADADLTARLLT----GGVPVT
TH_4360|M.thermoresistible__bu --------------------------------------------------
Mb2400c|M.bovis_AF2122/97 LEGADPPLGARRVAPQTDRVGELAITMSISDADLTARLLS----TGRSMT
Rv2379c|M.tuberculosis_H37Rv LEGADPPLGARRVAPQTDRVGELAITMSISDADLTARLLS----TGRSMT
MAV_2014|M.avium_104 LDGDDPDLGARRVDPARDRARDLLVRNVATDADLTRRLLE----SGLPLP
Mflv_2697|M.gilvum_PYR-GCK LGGPDPALGARRVRPDTDRAGDVRVTVTVTGADVTARLLA----GPHPVL
Mvan_3844|M.vanbaalenii_PYR-1 LAGSDPLLGRRLPDPRHDTWSTLQSTDVVTDAGATRAILDRLDGASLEVR
MMAR_3690|M.marinum_M VREPDPALGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVR-RDQGVR
MUL_3633|M.ulcerans_Agy99 VREPDPELGLRYPDPTRDTWSTLQLTRAAIPVDVTERVLGAVR-RDQGVR
MAB_2123|M.abscessus_ATCC_1997 VSGADPELGSRHADPSRDTWGTLQTTAVPTPVAVTTRLLASLN-KPEGVY
MLBr_02546|M.leprae_Br4923 --------------------------------------------------
MSMEG_4510|M.smegmatis_MC2_155 EVLAAATARTVTAWRRERGQPTPA-PLLALETHGRADAVVSADLGEDPHQ
TH_4360|M.thermoresistible__bu --------------------------------------------------
Mb2400c|M.bovis_AF2122/97 DLLATAAARMVTAWRRQRGQQTPA-PLLALETHGRADVHVDK-------T
Rv2379c|M.tuberculosis_H37Rv DLLATAAARMVTAWRRQRGQQTPA-PLLALETHGRADVHVDK-------T
MAV_2014|M.avium_104 TLLVAATAATVTRWRRQRGQSTPP-PLLALETHGRADSLVDG---PGAHT
Mflv_2697|M.gilvum_PYR-GCK DVLVAALGRTITEWRGRRNQPTPP-PLVALETHGRA-ALAEADTADTADT
Mvan_3844|M.vanbaalenii_PYR-1 DFLLTALTLTLASWRIERGQPAHHGALVALEGHGREDALVGG-------G
MMAR_3690|M.marinum_M ELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDT--------
MUL_3633|M.ulcerans_Agy99 ELLLAATAMAVASWRRVRAQDPAAGVLVALEGHGRADAVLDT--------
MAB_2123|M.abscessus_ATCC_1997 SFLLSALAVTVASWRKLRGQDSTAGTLVSLEGHGRADGELDT--------
MLBr_02546|M.leprae_Br4923 --------------------------------------------------
MSMEG_4510|M.smegmatis_MC2_155 VDTGDTAGLLSMIYPLRVTAGDA------------------RGVAELVAA
TH_4360|M.thermoresistible__bu --------------------------------------------------
Mb2400c|M.bovis_AF2122/97 ADTSDTVGLLSAIYPLRIHCDGA------------------TDFAR----
Rv2379c|M.tuberculosis_H37Rv ADTSDTVGLLSAIYPLRIHCDGA------------------TDFAR----
MAV_2014|M.avium_104 IDTGDTVGLLSSIYPIRVDAADP------------------RRVADKLAA
Mflv_2697|M.gilvum_PYR-GCK ADTSDTVGLLSAIYPLRLHEDSP------------------GATTELIAG
Mvan_3844|M.vanbaalenii_PYR-1 VDTSATVGWFTSVYPVRLGAGEAAIDVDTAARNPAAARSLLRAVIQQLAE
MMAR_3690|M.marinum_M -DTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEA
MUL_3633|M.ulcerans_Agy99 -DTTNTVGWFTNAFPVRLGAGAAAVDIEQAERDPVAAQDLVHSVVSHLEA
MAB_2123|M.abscessus_ATCC_1997 -DTSGTVGWFTTVYPVRVAAGEAAIDVDRMENDVNAARQLLAGVARHIDE
MLBr_02546|M.leprae_Br4923 --------------------------------------------------
MSMEG_4510|M.smegmatis_MC2_155 IPGDPIDYGLLRHLREDTAESLGVHRDPQLLLNYLGRIELDSAD----HA
TH_4360|M.thermoresistible__bu --------------------------------------------------
Mb2400c|M.bovis_AF2122/97 IPGSGIDYGLLRYLRADTAERLRAHREPQLLLNYLGSLHVGVG------D
Rv2379c|M.tuberculosis_H37Rv IPGSGIDYGLLRYLRADTAERLRAHREPQLLLNYLGSLHVGVG------D
MAV_2014|M.avium_104 IPGDGLDYGLLRYLRDDTAERLAALPSPQLLLNYLGAAHTDGG-----TG
Mflv_2697|M.gilvum_PYR-GCK VPAGGIDYGLLRYLRPDTSEVLKAHPEPQILLNYLGRTDLVPS-----GA
Mvan_3844|M.vanbaalenii_PYR-1 VPDKGLDYGLLRYTRRD--ETLRALPEPQVEFNYIGRYDLSADQTSQAWS
MMAR_3690|M.marinum_M IPNDGLDYGLLRY--VDGVAELVDAVDPQIQFSYLGRLDLGGVA-DQPWS
MUL_3633|M.ulcerans_Agy99 IPNDGLDYGLLRY--VDGVAELVDAVDPQIQFSYLGRLDLGGVA-DQPWS
MAB_2123|M.abscessus_ATCC_1997 IPYQGLDYGLLRY--VRGCEELSSARDPQIQFNYVGRMDISGID-DQPWS
MLBr_02546|M.leprae_Br4923 --------------------------------------------------
MSMEG_4510|M.smegmatis_MC2_155 LLQDRSLLSGVTPIPEPDVAVRHELTIMAAVIDRDGSAVLGAQWRTLPDI
TH_4360|M.thermoresistible__bu --------------------------------------------------
Mb2400c|M.bovis_AF2122/97 LAVDRALLADVGQLPEPEQPVRHELTVLAALLGPADAPVLATRWRTLPDI
Rv2379c|M.tuberculosis_H37Rv LAVDRALLADVGQLPEPEQPVRHELTVLAALLGPADAPVLATRWRTLPDI
MAV_2014|M.avium_104 LTLERELLAGLSPIPEPDLAVRHELTIAAMVLTYGGQRVLAAQWRTLPDI
Mflv_2697|M.gilvum_PYR-GCK IVADRLLLSGLSTVPEPNAAVRHELTVVAAVVAHGDEPALVAQWRVLPEI
Mvan_3844|M.vanbaalenii_PYR-1 LITDETLNAHMPAAAEPDLPLRYTFDVISVISGGADGPQLRTSWRWSTAL
MMAR_3690|M.marinum_M LLTG-PYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSDAV
MUL_3633|M.ulcerans_Agy99 LLTG-PYLDALPIDPEPDLPLRFALNLSVFVGVTAEGTQLIGNWRWSDAV
MAB_2123|M.abscessus_ATCC_1997 LITD-ARSLAVPPDSEPDLPLRFAINIGSAVMTTPEGPQLLTNWQLSSAL
MLBr_02546|M.leprae_Br4923 --------------------------------------------------
MSMEG_4510|M.smegmatis_MC2_155 LSAAEVGTLQTMWLDALREVVE----
TH_4360|M.thermoresistible__bu --------------------------
Mb2400c|M.bovis_AF2122/97 LSADDVATLQSLWQGALAEITA----
Rv2379c|M.tuberculosis_H37Rv LSADDVATLQSLWQGALAEITA----
MAV_2014|M.avium_104 LTDTDITALQELWVDSLREMVT----
Mflv_2697|M.gilvum_PYR-GCK LSDTDVEEMQTIWQDTLREVL-----
Mvan_3844|M.vanbaalenii_PYR-1 STSTEVDRLTALWQQAVTVLGEAL--
MMAR_3690|M.marinum_M FERSDIDHLTGLWQRGIAALAAGLD-
MUL_3633|M.ulcerans_Agy99 FERSDIDHLTGLWQRGIAALAAGLD-
MAB_2123|M.abscessus_ATCC_1997 FTPADASRLAQLWQRSVAALAGALDG
MLBr_02546|M.leprae_Br4923 --------------------------