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M. thermoresistible (build 8) TH_4297 (dapB)

annotation: putative dihydrodipicolinate reductase, N-terminus domain protein
coordinates: 3457908 - 3458993
length: 362

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4297dapB-100% (362)putative dihydrodipicolinate reductase, N-terminus domain protein
M. thermoresistible (build 8)TH_0599-8e-6943.02% (358) conserved hypothetical protein
M. thermoresistible (build 8)TH_3380-1e-6141.21% (347) PUTATIVE dihydrodipicolinate reductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0949c-4e-7142.00% (350) hypothetical protein Mb0949c
M. gilvum PYR-GCKMflv_3282-1e-6540.63% (347) dihydrodipicolinate reductase
M. tuberculosis H37RvRv0926c-4e-7142.00% (350) hypothetical protein Rv0926c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4633-3e-7143.43% (350) hypothetical protein MAB_4633
M. marinum MMMAR_4582-5e-7343.52% (347) hypothetical protein MMAR_4582
M. avium 104MAV_4999dapB2e-8143.94% (355) dihydrodipicolinate reductase N-terminus domain-containing
M. smegmatis MC2 155MSMEG_5586-1e-6842.27% (343) hypothetical protein MSMEG_5586
M. ulcerans Agy99MUL_4353-4e-3732.32% (362) hypothetical protein MUL_4353
M. vanbaalenii PYR-1Mvan_4922-7e-6340.41% (344) dihydrodipicolinate reductase

CLUSTAL 2.0.9 multiple sequence alignment


TH_4297|M.thermoresistible__bu      --------VILWGPGQVGVGALRAVIAHPGLELVGLVVHSPAKHGKDAGA
MAV_4999|M.avium_104                -----MYKVGVWGPGSMGVIALRGVIDHPQLELVDLVVHSDAKAGRDAGE
Mb0949c|M.bovis_AF2122/97           ----MAIPVVQLGTGNVGVHSLRALIADPEFELTGVWVSSDAKAGKDAAE
Rv0926c|M.tuberculosis_H37Rv        ----MAIPVVQLGTGNVGVHSLRALIADPEFELTGVWVSSDAKAGKDAAE
MMAR_4582|M.marinum_M               ----MAIPVVQLGTGNVGLHSLRALITNPEFELTGVWVSSDAKAGKDAAE
MSMEG_5586|M.smegmatis_MC2_155      ----MAIRVAAIGTGNVGRHALRQLITNPAYELTAVWVSSPEKAGKDAGD
Mvan_4922|M.vanbaalenii_PYR-1       ----MAIKVAAIGTGNVGRHALTQLITDPRFELTAVWVSSESKAGKDAAE
MAB_4633|M.abscessus_ATCC_1997      ---MTKTRVAVWGTGNVGQHALAGVITDPSMELVGVWVSGSNKAGKDAGA
Mflv_3282|M.gilvum_PYR-GCK          ----MAIRVALIGTGNCGSLALRQLIEDARFDLVGVWVSTPAKVGKDAGE
MUL_4353|M.ulcerans_Agy99           MSGPAKLRVIQWATGGVGKAAIECILNHPQLELAGCWVHSAAKHGLDVGT
                                            *   ..*  *  ::  :: ..  :*.   *    * * *.. 

TH_4297|M.thermoresistible__bu      LCGMPE-TGILATNDIDAALAVDADVVAYFASGDYRYREAAEDIARCLRA
MAV_4999|M.avium_104                LCGVAP-VGVVATQDPAAMLAGDADAVVYAAGANLRPLEAVEDMVSILRA
Mb0949c|M.bovis_AF2122/97           LAGLADSTGVRASTDLNAVLATGPRCAVYNAMADNRLPEALEDYRRILAA
Rv0926c|M.tuberculosis_H37Rv        LAGLADSTGVRASTDLNAVLATGPRCAVYNAMADNRLPEALEDYRRILAA
MMAR_4582|M.marinum_M               LAGFAESTGVKASTDLDAVLASGPQCAVYNAMADNRLPEALDDYRRVLAA
MSMEG_5586|M.smegmatis_MC2_155      LAGLEVTTGIKATDSLDEVLATEPECAVYTAMADNRLPDALEDYRRILAA
Mvan_4922|M.vanbaalenii_PYR-1       LVGLADSTGIRATTDLDAVLATRPQCAVYTALADNRLPEALEDYRRILAA
MAB_4633|M.abscessus_ATCC_1997      LAGLDILTGITATTDAAQILALRPDCVVYTAMTDNRLMEALKDLTDLLSA
Mflv_3282|M.gilvum_PYR-GCK          LARLDVTTGIAATDDLDALVATRPDCVVYCAMGDVRPREALADVRKLLEA
MUL_4353|M.ulcerans_Agy99           IIGAAR-FGVTATNDVDELLALDADCVMYSPQVADE-----QDVKAILRS
                                    :       *: *: .    :*  .  . * .    .      *    * :

TH_4297|M.thermoresistible__bu      GKNVVTTSLVPLCYP-PAADAETVDLIEAACAEGRTTFFNSGVDPGWAND
MAV_4999|M.avium_104                GKNVVSCSVVPLVFP-DAVDSAFTEPLRAAALEGQVSFFTTGIDSGFAND
Mb0949c|M.bovis_AF2122/97           GINIVGSGPVFLQYPWQVIPDEIIKPLQDAARAGNSSLYVNGIDPGFAND
Rv0926c|M.tuberculosis_H37Rv        GINIVGSGPVFLQYPWQVIPDEIIKPLQDAARAGNSSLYVNGIDPGFAND
MMAR_4582|M.marinum_M               GVNIVGSGPVFLQYPWQVLPDELVKPLEDAAREGNSSLYVSGIDPGFAND
MSMEG_5586|M.smegmatis_MC2_155      GVNVVGSSAVFLQYPWQVLPEELVKPIEDAAHAGGASLFVNGIDPGFAND
Mvan_4922|M.vanbaalenii_PYR-1       GVNVVGSSAVFLQHPWKVLPDELIAPIEDAAKAGSSTIFVNGIDPGFAND
MAB_4633|M.abscessus_ATCC_1997      GINVAASAPVFLQYPWGVLPENMLTPIENAAREGNSSIFAGGIDPGFAND
Mflv_3282|M.gilvum_PYR-GCK          GINVVGSSPGFLSYPWGVIGDHTIEKVQAAARQGNSSLFITGVDPGFVTD
MUL_4353|M.ulcerans_Agy99           GKNVFTP----VGWVYPDLSKPRVKAVADAAVAGGVTLHGSGIHPGGITE
                                    * *:       :              :  *.  *  ::.  *:..*  .:

TH_4297|M.thermoresistible__bu      LMALTMTGFSSRVDTITMLEILDYAPINQPEIMFDFMGFGHPPEHPAPLF
MAV_4999|M.avium_104                VLPLVLTGVSRVIESVRVTEMFNYATYPDASAVYEILGFGQPPDHPAFAA
Mb0949c|M.bovis_AF2122/97           LLPMALAGTCESIEQIRCMEIVDYATYDSAVVMFDVMGFGKPMDQIPMLL
Rv0926c|M.tuberculosis_H37Rv        LLPMALAGTCESIEQIRCMEIVDYATYDSAVVMFDVMGFGKPMDQIPMLL
MMAR_4582|M.marinum_M               LLPMALAGTCQSIEQIRCMEIVDYATYDSAVVMFDVMGFGKPLDEIPMLL
MSMEG_5586|M.smegmatis_MC2_155      LLPLALAGTCQQIEQIRCMEIVDYATYDSATVMLDVMGFGKSLDETPMLL
Mvan_4922|M.vanbaalenii_PYR-1       LLPMALAGTCQSIQQIRCMEIINYDTYDSAPVMFDVMGFGGSLDETPMLL
MAB_4633|M.abscessus_ATCC_1997      LLPLALMGTCQRIDQVRCIEIVDYATYDSATVMFDVMGFGKPMEETPMLL
Mflv_3282|M.gilvum_PYR-GCK          LLPLALASTCQHIEQIRTMEIADYATYDGATVMFDVMGFGNEIGDLPFLY
MUL_4353|M.ulcerans_Agy99           RFPLMVSSLSSAITHVRAEEFSDIRTYNAPDVVRDIMGFGVPHAQAMQGP
                                     :.: : . .  :  :   *: :  .   .  : :.:***    .     

TH_4297|M.thermoresistible__bu      DPERLAALWAPTVHLVADGVGLPLD-RVETTIDKWLATERYRVASGWIEP
MAV_4999|M.avium_104                QPGIFTFGWGPVLHQLAAGLGVEID-HIEESNERIPAPESFDTPTGHIAA
Mb0949c|M.bovis_AF2122/97           QPGVLSLAWGSVVRQLAAGLGISLD-GVEEMYVREPAPEAFNIASGHIPK
Rv0926c|M.tuberculosis_H37Rv        QPGVLSLAWGSVVRQLAAGLGISLD-GVEEMYVREPAPEAFNIASGHIPK
MMAR_4582|M.marinum_M               QPGVLSLAWGSVVRQLAAGLGLSLD-VVEEMYVREPAPHAFDIASGHIPQ
MSMEG_5586|M.smegmatis_MC2_155      QPGVLSLAWGSVVRQLAAGLGIELD-AVTEEHTRVPAPEDFDIAAGHISE
Mvan_4922|M.vanbaalenii_PYR-1       QPGVLSLAWGSVVRQLAAGLGIELD-EVTETHLRVPAPEAFDIAAGRIEK
MAB_4633|M.abscessus_ATCC_1997      QPGVLSLAWGSVVRQLAAGLGVELD-EVTEVYEKLSAPEDFDISSGHIPA
Mflv_3282|M.gilvum_PYR-GCK          QPGMLSAAWGVGIRQLAAGLGVEVE-EIRDSVEQEPAPEDFEVAVGTIRK
MUL_4353|M.ulcerans_Agy99           MAALLESGFKMSVRMIANHMGFHIDPMIRATHEIAVATSDIASDVLPIAA
                                     .  :   :   :: :*  :*. ::  :        *.         *  

TH_4297|M.thermoresistible__bu      GTMGGMRFKLAGIVDGEPRVVLEHITRM-GEHSAPDWPR-----------
MAV_4999|M.avium_104                GTIAAMRSTLTGYVGAKPTFVLDHVTRM-RDDLAPDWPQPRIAIAPKDLG
Mb0949c|M.bovis_AF2122/97           GSAAALRFEVLGLVDGVPAVVLEHVTRL-RADLCPEWPQP----------
Rv0926c|M.tuberculosis_H37Rv        GSAAALRFEVLGLVDGVPAVVLEHVTRL-RADLCPEWPQP----------
MMAR_4582|M.marinum_M               GSAAALRFEVLGLVDGAPVVVLEHVTRL-REDLCPDWPQP----------
MSMEG_5586|M.smegmatis_MC2_155      GTTAAMRFEVRGMVDGKPAVVLEHVTRL-RDDLCPEWPQP----------
Mvan_4922|M.vanbaalenii_PYR-1       GTTAAIRFEVRGMKDGEVAVVLEHVTRL-RDDLCPDWPQP----------
MAB_4633|M.abscessus_ATCC_1997      GTMAALHFEVRGIKDGRAVTVLEHFTRL-REDLAPNWPQP----------
Mflv_3282|M.gilvum_PYR-GCK          GTVAAVRFLIEGLVDGRPAIVVEHITRL-RGDLRPDWAQP----------
MUL_4353|M.ulcerans_Agy99           DTVAGRKFRWQTLADGKPVITAAVNWLMGQADMHPDWSFG----------
                                    .: .. :       ..    .      :   .  *:*.            

TH_4297|M.thermoresistible__bu      --HPSPHGGYRVVVDGLPTYTVDIE----MHG-RGNNMRGLTYATVMREL
MAV_4999|M.avium_104                YGLASGRGLYRVEIEGSPSMRCEFE----MAE-DHDHDLGARIAGSSRMV
Mb0949c|M.bovis_AF2122/97           ---AQPGGSYRIEISGEPCYAMDIC----LSSRHGDHNHAGLVATAMRIV
Rv0926c|M.tuberculosis_H37Rv        ---AQPGGSYRIEISGEPCYAMDIC----LSSRHGDHNHAGLVATAMRIV
MMAR_4582|M.marinum_M               ---AQPGGSYRIEITGEPSYAMDLC----LSSRRGDHNHAGLVATAMRVV
MSMEG_5586|M.smegmatis_MC2_155      ---AQEGGSYRVEVTGEPSYALDLC----LSSPYGDHNHAGLVATAARVV
Mvan_4922|M.vanbaalenii_PYR-1       ---AQHGGSYRIEITGEPSYALDLC----LSSPNGDHNHAGLVATAARVV
MAB_4633|M.abscessus_ATCC_1997      ---AHEGGTYRVEITGEPSYLLDLG----SFSARGDHNYANLIATAMRVV
Mflv_3282|M.gilvum_PYR-GCK          ---AQEGGSYRVEITGEPSYVMDIR----PTSRNGDHNYAAILAAAGRIV
MUL_4353|M.ulcerans_Agy99           ----ERGERFEIEITGNPSVSLVFKGLQPTSITEGLQRNPGVVATANHCA
                                             :.: : * *     :            :      *   :  

TH_4297|M.thermoresistible__bu      NAIPAVVAAPPGLLSTLDLPLVTGPVRGGRWTGTLPPTTRR-
MAV_4999|M.avium_104                NAIPAVCAAPPGLLSALDLPLITG-AGLVRPVPGPPPDSRLF
Mb0949c|M.bovis_AF2122/97           NAIPAVVAAEPGIRTTLDLPLITG---EGRYAAA--------
Rv0926c|M.tuberculosis_H37Rv        NAIPAVVAAEPGIRTTLDLPLITG---EGRYAAA--------
MMAR_4582|M.marinum_M               NAIPAVVAAPPGIRTTLELPLVTG---KGLYLPPAGAA----
MSMEG_5586|M.smegmatis_MC2_155      NAIPAVFAAPPGIRTTLDMPLITG---KGLYAAR--------
Mvan_4922|M.vanbaalenii_PYR-1       NAIPAVIDAAPGIVTARELPPITG---EGLYAKP--------
MAB_4633|M.abscessus_ATCC_1997      NAVPAVVAAEAGIRTTLDLPLITG---KGRAV----------
Mflv_3282|M.gilvum_PYR-GCK          NAIPEVVAAEAGIRTTLDLPLVTG---NGTYRPA--------
MUL_4353|M.ulcerans_Agy99           NAIPVVCAADPGIATYLDLPLFAG--RPARASRGLER-----
                                    **:* *  * .*: :  ::* .:*