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M. thermoresistible (build 8) TH_0599 (-)

annotation: conserved hypothetical protein
coordinates: 1270977 - 1272077
length: 367

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0599--100% (367)conserved hypothetical protein
M. thermoresistible (build 8)TH_4586-4e-7244.51% (346) PUTATIVE dihydrodipicolinate reductase
M. thermoresistible (build 8)TH_4297-8e-6943.02% (358) PUTATIVE putative dihydrodipicolinate reductase, N-terminus

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0949c-1e-15875.21% (355) hypothetical protein Mb0949c
M. gilvum PYR-GCKMflv_1824-1e-15876.82% (358) dihydrodipicolinate reductase
M. tuberculosis H37RvRv0926c-1e-15875.21% (355) hypothetical protein Rv0926c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4633-1e-13967.81% (351) hypothetical protein MAB_4633
M. marinum MMMAR_4582-1e-15975.42% (358) hypothetical protein MMAR_4582
M. avium 104MAV_1045dapB1e-15676.00% (350) dihydrodipicolinate reductase N-terminus domain-containing
M. smegmatis MC2 155MSMEG_5586-1e-16278.59% (355) hypothetical protein MSMEG_5586
M. ulcerans Agy99MUL_4353-8e-4032.59% (359) hypothetical protein MUL_4353
M. vanbaalenii PYR-1Mvan_4922-1e-15474.30% (358) dihydrodipicolinate reductase

CLUSTAL 2.0.9 multiple sequence alignment


Mb0949c|M.bovis_AF2122/97           ----MAIPVVQLGTGNVGVHSLRALIADPEFELTGVWVSSDAKAGKDAAE
Rv0926c|M.tuberculosis_H37Rv        ----MAIPVVQLGTGNVGVHSLRALIADPEFELTGVWVSSDAKAGKDAAE
MMAR_4582|M.marinum_M               ----MAIPVVQLGTGNVGLHSLRALITNPEFELTGVWVSSDAKAGKDAAE
MAV_1045|M.avium_104                ----MPIPVVQLGTGNVGIHALRALITDPQFELTGVWVSSDAKAGKDAAE
Mflv_1824|M.gilvum_PYR-GCK          ----MAIKVAAVGTGNVGRHALAQLINDPRFELTAVWVSSEAKAGKDAAE
Mvan_4922|M.vanbaalenii_PYR-1       ----MAIKVAAIGTGNVGRHALTQLITDPRFELTAVWVSSESKAGKDAAE
MSMEG_5586|M.smegmatis_MC2_155      ----MAIRVAAIGTGNVGRHALRQLITNPAYELTAVWVSSPEKAGKDAGD
TH_0599|M.thermoresistible__bu      ----VTIRTAVVGTGNVGRHALAQVIADPRFDLTAVWVSSAAKAGLDAGE
MAB_4633|M.abscessus_ATCC_1997      ---MTKTRVAVWGTGNVGQHALAGVITDPSMELVGVWVSGSNKAGKDAGA
MUL_4353|M.ulcerans_Agy99           MSGPAKLRVIQWATGGVGKAAIECILNHPQLELAGCWVHSAAKHGLDVGT
                                            .   .**.**  ::  :: .*  :*.. ** .  * * *.. 

Mb0949c|M.bovis_AF2122/97           LAGLADSTGVRASTDLNAVLATGPRCAVYNAMADNRLPEALEDYRRILAA
Rv0926c|M.tuberculosis_H37Rv        LAGLADSTGVRASTDLNAVLATGPRCAVYNAMADNRLPEALEDYRRILAA
MMAR_4582|M.marinum_M               LAGFAESTGVKASTDLDAVLASGPQCAVYNAMADNRLPEALDDYRRVLAA
MAV_1045|M.avium_104                LAGLAQPTGVLASTDLDAVLATGPRCAVYNALADNRLPEALDDYRRVLAA
Mflv_1824|M.gilvum_PYR-GCK          LAGLQDSTGIRATTDLDEVLATRPECVVYTALADNRLPDALEDYRRILAA
Mvan_4922|M.vanbaalenii_PYR-1       LVGLADSTGIRATTDLDAVLATRPQCAVYTALADNRLPEALEDYRRILAA
MSMEG_5586|M.smegmatis_MC2_155      LAGLEVTTGIKATDSLDEVLATEPECAVYTAMADNRLPDALEDYRRILAA
TH_0599|M.thermoresistible__bu      LAGLDVSTGIRATTDLDELLATGPECVVYTAMADNRLNEALDDYRRILAA
MAB_4633|M.abscessus_ATCC_1997      LAGLDILTGITATTDAAQILALRPDCVVYTAMTDNRLMEALKDLTDLLSA
MUL_4353|M.ulcerans_Agy99           IIGAAR-FGVTATNDVDELLALDADCVMYSPQVAD-----EQDVKAILRS
                                    : *     *: *: .   :**  . *.:*.. . :      .*   :* :

Mb0949c|M.bovis_AF2122/97           GINIVGSGPVFLQYPWQVIPDEIIKPLQDAARAGNSSLYVNGIDPGFAND
Rv0926c|M.tuberculosis_H37Rv        GINIVGSGPVFLQYPWQVIPDEIIKPLQDAARAGNSSLYVNGIDPGFAND
MMAR_4582|M.marinum_M               GVNIVGSGPVFLQYPWQVLPDELVKPLEDAAREGNSSLYVSGIDPGFAND
MAV_1045|M.avium_104                GINIVGSGPVFLQYPWQVIPDELIKPLEEAAQQGNSSLYVNGIDPGFAND
Mflv_1824|M.gilvum_PYR-GCK          GVNVVGSSAVFLQHPWQVLPAELISPIEDAAKAGNASLFVNGIDPGFAND
Mvan_4922|M.vanbaalenii_PYR-1       GVNVVGSSAVFLQHPWKVLPDELIAPIEDAAKAGSSTIFVNGIDPGFAND
MSMEG_5586|M.smegmatis_MC2_155      GVNVVGSSAVFLQYPWQVLPEELVKPIEDAAHAGGASLFVNGIDPGFAND
TH_0599|M.thermoresistible__bu      GSNVVGSSAVFLQHPWQVLPAELIAPIEEAATAGNASLYVNGIDPGFAND
MAB_4633|M.abscessus_ATCC_1997      GINVAASAPVFLQYPWGVLPENMLTPIENAAREGNSSIFAGGIDPGFAND
MUL_4353|M.ulcerans_Agy99           GKNVFTP----VGWVYPDLSKPRVKAVADAAVAGGVTLHGSGIHPGGITE
                                    * *:  .    :   :  :.   : .: :**  *. ::. .**.**  .:

Mb0949c|M.bovis_AF2122/97           LLPMALAGTCESIEQIRCMEIVDYATYDSAVVMFDVMGFGKPMDQIPMLL
Rv0926c|M.tuberculosis_H37Rv        LLPMALAGTCESIEQIRCMEIVDYATYDSAVVMFDVMGFGKPMDQIPMLL
MMAR_4582|M.marinum_M               LLPMALAGTCQSIEQIRCMEIVDYATYDSAVVMFDVMGFGKPLDEIPMLL
MAV_1045|M.avium_104                LLPLALAGTCQSIQQIRCMEIVDYATYDSAAVMFDVMGFGKPLDDVPMLL
Mflv_1824|M.gilvum_PYR-GCK          LLPMALAGTCQSIQQIRCMEIINYDTYDSAAVMFDVMGFGGSLDETPMLL
Mvan_4922|M.vanbaalenii_PYR-1       LLPMALAGTCQSIQQIRCMEIINYDTYDSAPVMFDVMGFGGSLDETPMLL
MSMEG_5586|M.smegmatis_MC2_155      LLPLALAGTCQQIEQIRCMEIVDYATYDSATVMLDVMGFGKSLDETPMLL
TH_0599|M.thermoresistible__bu      QLPLALAGACQHIEQIRCLEIVDYATYDSATVLFDVMGFGKPLDEIPLLL
MAB_4633|M.abscessus_ATCC_1997      LLPLALMGTCQRIDQVRCIEIVDYATYDSATVMFDVMGFGKPMEETPMLL
MUL_4353|M.ulcerans_Agy99           RFPLMVSSLSSAITHVRAEEFSDIRTYNAPDVVRDIMGFGVPHAQAMQGP
                                     :*: : . .. * ::*. *: :  **::. *: *:**** .  :     

Mb0949c|M.bovis_AF2122/97           QPGVLSLAWGSVVRQLAAGLGISLD-GVEEMYVREPAPEAFNIASGHIPK
Rv0926c|M.tuberculosis_H37Rv        QPGVLSLAWGSVVRQLAAGLGISLD-GVEEMYVREPAPEAFNIASGHIPK
MMAR_4582|M.marinum_M               QPGVLSLAWGSVVRQLAAGLGLSLD-VVEEMYVREPAPHAFDIASGHIPQ
MAV_1045|M.avium_104                QPGVLSLAWGSVVRQLAAGLGVSLD-EVTQQHVRVPAPEDFDIASGHIAK
Mflv_1824|M.gilvum_PYR-GCK          QPGVLSLAWGSVVRQLAAGLDIELD-EVTETHERVPAPESFDIAAGRIEE
Mvan_4922|M.vanbaalenii_PYR-1       QPGVLSLAWGSVVRQLAAGLGIELD-EVTETHLRVPAPEAFDIAAGRIEK
MSMEG_5586|M.smegmatis_MC2_155      QPGVLSLAWGSVVRQLAAGLGIELD-AVTEEHTRVPAPEDFDIAAGHISE
TH_0599|M.thermoresistible__bu      QPGVLTMAWGSVVRQLAAGLGIELD-EVREQYVREPAPEDFDIAAGHIPQ
MAB_4633|M.abscessus_ATCC_1997      QPGVLSLAWGSVVRQLAAGLGVELD-EVTEVYEKLSAPEDFDISSGHIPA
MUL_4353|M.ulcerans_Agy99           MAALLESGFKMSVRMIANHMGFHIDPMIRATHEIAVATSDIASDVLPIAA
                                     ..:*  .:   ** :*  :.. :*  :   :    *.  :      *  

Mb0949c|M.bovis_AF2122/97           GSAAALRFEVLGLVDGVPAVVLEHVTRL-RADLCPEWPQPAQPGGSYRIE
Rv0926c|M.tuberculosis_H37Rv        GSAAALRFEVLGLVDGVPAVVLEHVTRL-RADLCPEWPQPAQPGGSYRIE
MMAR_4582|M.marinum_M               GSAAALRFEVLGLVDGAPVVVLEHVTRL-REDLCPDWPQPAQPGGSYRIE
MAV_1045|M.avium_104                GTAAALRFEVFGMVDGRPVVVLEHVTRL-REDLCPDWPQPAQHGGSYRIE
Mflv_1824|M.gilvum_PYR-GCK          GTTAAIRFEVRGMKDGNVAVILEHVTRL-RDDLCPDWPQPAQHGGSYRIE
Mvan_4922|M.vanbaalenii_PYR-1       GTTAAIRFEVRGMKDGEVAVVLEHVTRL-RDDLCPDWPQPAQHGGSYRIE
MSMEG_5586|M.smegmatis_MC2_155      GTTAAMRFEVRGMVDGKPAVVLEHVTRL-RDDLCPEWPQPAQEGGSYRVE
TH_0599|M.thermoresistible__bu      GSAAALRFEVQGMVDGHPAVVLEHVTRL-RDDLRPDWPQPAQPGGSYRVE
MAB_4633|M.abscessus_ATCC_1997      GTMAALHFEVRGIKDGRAVTVLEHFTRL-REDLAPNWPQPAHEGGTYRVE
MUL_4353|M.ulcerans_Agy99           DTVAGRKFRWQTLADGKPVITAAVNWLMGQADMHPDWSFGER-GERFEIE
                                    .: *. :*.   : **  .        : : *: *:*.   : *  :.:*

Mb0949c|M.bovis_AF2122/97           ISGEPCYAMDIC----LSSRHGDHNHAGLVATAMRIVNAIPAVVAAEPGI
Rv0926c|M.tuberculosis_H37Rv        ISGEPCYAMDIC----LSSRHGDHNHAGLVATAMRIVNAIPAVVAAEPGI
MMAR_4582|M.marinum_M               ITGEPSYAMDLC----LSSRRGDHNHAGLVATAMRVVNAIPAVVAAPPGI
MAV_1045|M.avium_104                VTGEPSYAMDIC----LSSRKGDHNHAGLVATAMRVVNAIPAVVAAPPGI
Mflv_1824|M.gilvum_PYR-GCK          VTGEPSYAMDLC----LSSPNGDHNHAGLVATAARVVNAIPAVVDSSPGI
Mvan_4922|M.vanbaalenii_PYR-1       ITGEPSYALDLC----LSSPNGDHNHAGLVATAARVVNAIPAVIDAAPGI
MSMEG_5586|M.smegmatis_MC2_155      VTGEPSYALDLC----LSSPYGDHNHAGLVATAARVVNAIPAVFAAPPGI
TH_0599|M.thermoresistible__bu      VTGEPCYTLDLR----LSSPHGDHNHAGLVATAARVVNAIPPVVAAPAGI
MAB_4633|M.abscessus_ATCC_1997      ITGEPSYLLDLG----SFSARGDHNYANLIATAMRVVNAVPAVVAAEAGI
MUL_4353|M.ulcerans_Agy99           ITGNPSVSLVFKGLQPTSITEGLQRNPGVVATANHCANAIPVVCAADPGI
                                    ::*:*.  : :          * :. ..::*** : .**:* *  : .**

Mb0949c|M.bovis_AF2122/97           RTTLDLPLITGEGRYAAA--------
Rv0926c|M.tuberculosis_H37Rv        RTTLDLPLITGEGRYAAA--------
MMAR_4582|M.marinum_M               RTTLELPLVTGKGLYLPPAGAA----
MAV_1045|M.avium_104                VTTLDLPLITGRGLYRPE--------
Mflv_1824|M.gilvum_PYR-GCK          VTARELPPITGKGLYANP--------
Mvan_4922|M.vanbaalenii_PYR-1       VTARELPPITGEGLYAKP--------
MSMEG_5586|M.smegmatis_MC2_155      RTTLDMPLITGKGLYAAR--------
TH_0599|M.thermoresistible__bu      RTTLDLPWVSGTGRYLPPDRPEGTIR
MAB_4633|M.abscessus_ATCC_1997      RTTLDLPLITGKGRAV----------
MUL_4353|M.ulcerans_Agy99           ATYLDLPLFAGRPARASRGLER----
                                     *  ::* .:*