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LAIKVAAIGTGNVGRHALTQLITDPRFELTAVWVSSESKAGKDAAELVGLADSTGIRATTDLDAVLATRP QCAVYTALADNRLPEALEDYRRILAAGVNVVGSSAVFLQHPWKVLPDELIAPIEDAAKAGSSTIFVNGID PGFANDLLPMALAGTCQSIQQIRCMEIINYDTYDSAPVMFDVMGFGGSLDETPMLLQPGVLSLAWGSVVR QLAAGLGIELDEVTETHLRVPAPEAFDIAAGRIEKGTTAAIRFEVRGMKDGEVAVVLEHVTRLRDDLCPD WPQPAQHGGSYRIEITGEPSYALDLCLSSPNGDHNHAGLVATAARVVNAIPAVIDAAPGIVTARELPPIT GEGLYAKP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4922 | - | - | 100% (358) | dihydrodipicolinate reductase |
| M. vanbaalenii PYR-1 | Mvan_3001 | - | e-122 | 58.10% (358) | dihydrodipicolinate reductase |
| M. vanbaalenii PYR-1 | Mvan_4970 | - | 2e-70 | 42.65% (347) | dihydrodipicolinate reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0949c | - | 1e-158 | 75.28% (356) | hypothetical protein Mb0949c |
| M. gilvum PYR-GCK | Mflv_1824 | - | 0.0 | 91.06% (358) | dihydrodipicolinate reductase |
| M. tuberculosis H37Rv | Rv0926c | - | 1e-158 | 75.28% (356) | hypothetical protein Rv0926c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4633 | - | 1e-134 | 65.71% (350) | hypothetical protein MAB_4633 |
| M. marinum M | MMAR_4582 | - | 1e-159 | 75.42% (358) | hypothetical protein MMAR_4582 |
| M. avium 104 | MAV_1045 | dapB | 1e-163 | 77.46% (355) | dihydrodipicolinate reductase N-terminus domain-containing |
| M. smegmatis MC2 155 | MSMEG_5586 | - | 1e-168 | 81.18% (356) | hypothetical protein MSMEG_5586 |
| M. thermoresistible (build 8) | TH_0599 | - | 1e-154 | 74.30% (358) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3685 | - | 9e-36 | 31.73% (353) | hypothetical protein MUL_3685 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0949c|M.bovis_AF2122/97 ----MAIPVVQLGTGNVGVHSLRALIADPEFELTGVWVSSDAKAGKDAAE
Rv0926c|M.tuberculosis_H37Rv ----MAIPVVQLGTGNVGVHSLRALIADPEFELTGVWVSSDAKAGKDAAE
MMAR_4582|M.marinum_M ----MAIPVVQLGTGNVGLHSLRALITNPEFELTGVWVSSDAKAGKDAAE
MAV_1045|M.avium_104 ----MPIPVVQLGTGNVGIHALRALITDPQFELTGVWVSSDAKAGKDAAE
Mvan_4922|M.vanbaalenii_PYR-1 ----MAIKVAAIGTGNVGRHALTQLITDPRFELTAVWVSSESKAGKDAAE
Mflv_1824|M.gilvum_PYR-GCK ----MAIKVAAVGTGNVGRHALAQLINDPRFELTAVWVSSEAKAGKDAAE
MSMEG_5586|M.smegmatis_MC2_155 ----MAIRVAAIGTGNVGRHALRQLITNPAYELTAVWVSSPEKAGKDAGD
TH_0599|M.thermoresistible__bu ----VTIRTAVVGTGNVGRHALAQVIADPRFDLTAVWVSSAAKAGLDAGE
MAB_4633|M.abscessus_ATCC_1997 ---MTKTRVAVWGTGNVGQHALAGVITDPSMELVGVWVSGSNKAGKDAGA
MUL_3685|M.ulcerans_Agy99 MSTARPLRVIQWTTGNIGRRSLHAIIGRPDLELVGVYAHGPDKVGVDAAE
. ***:* ::* :* * :*..*:. . *.* **.
Mb0949c|M.bovis_AF2122/97 LAGLADSTGVRASTDLNAVLATGPRCAVYNAMADNRLPEALEDYRRILAA
Rv0926c|M.tuberculosis_H37Rv LAGLADSTGVRASTDLNAVLATGPRCAVYNAMADNRLPEALEDYRRILAA
MMAR_4582|M.marinum_M LAGFAESTGVKASTDLDAVLASGPQCAVYNAMADNRLPEALDDYRRVLAA
MAV_1045|M.avium_104 LAGLAQPTGVLASTDLDAVLATGPRCAVYNALADNRLPEALDDYRRVLAA
Mvan_4922|M.vanbaalenii_PYR-1 LVGLADSTGIRATTDLDAVLATRPQCAVYTALADNRLPEALEDYRRILAA
Mflv_1824|M.gilvum_PYR-GCK LAGLQDSTGIRATTDLDEVLATRPECVVYTALADNRLPDALEDYRRILAA
MSMEG_5586|M.smegmatis_MC2_155 LAGLEVTTGIKATDSLDEVLATEPECAVYTAMADNRLPDALEDYRRILAA
TH_0599|M.thermoresistible__bu LAGLDVSTGIRATTDLDELLATGPECVVYTAMADNRLNEALDDYRRILAA
MAB_4633|M.abscessus_ATCC_1997 LAGLDILTGITATTDAAQILALRPDCVVYTAMTDNRLMEALKDLTDLLSA
MUL_3685|M.ulcerans_Agy99 LAGWPDPTGVRATSDIGALLALGADACCYNPLWPN-----IDELVGLLES
*.* **: *: . :** . . *..: * :.: :* :
Mb0949c|M.bovis_AF2122/97 GINIVGSGPVFLQYPWQVIPDEIIKPLQDAARAGNSSLYVNGIDPGFAND
Rv0926c|M.tuberculosis_H37Rv GINIVGSGPVFLQYPWQVIPDEIIKPLQDAARAGNSSLYVNGIDPGFAND
MMAR_4582|M.marinum_M GVNIVGSGPVFLQYPWQVLPDELVKPLEDAAREGNSSLYVSGIDPGFAND
MAV_1045|M.avium_104 GINIVGSGPVFLQYPWQVIPDELIKPLEEAAQQGNSSLYVNGIDPGFAND
Mvan_4922|M.vanbaalenii_PYR-1 GVNVVGSSAVFLQHPWKVLPDELIAPIEDAAKAGSSTIFVNGIDPGFAND
Mflv_1824|M.gilvum_PYR-GCK GVNVVGSSAVFLQHPWQVLPAELISPIEDAAKAGNASLFVNGIDPGFAND
MSMEG_5586|M.smegmatis_MC2_155 GVNVVGSSAVFLQYPWQVLPEELVKPIEDAAHAGGASLFVNGIDPGFAND
TH_0599|M.thermoresistible__bu GSNVVGSSAVFLQHPWQVLPAELIAPIEEAATAGNASLYVNGIDPGFAND
MAB_4633|M.abscessus_ATCC_1997 GINVAASAPVFLQYPWGVLPENMLTPIENAAREGNSSIFAGGIDPGFAND
MUL_3685|M.ulcerans_Agy99 GVNVCTSAAWITGG--KQTPRDRER-ILAACERGGATIFGSDAHPGMTN-
* *: *.. : * : : *. *.:::: .. .**::*
Mb0949c|M.bovis_AF2122/97 LLPMALAGTCESIEQIRCMEIVDYATYDSAVVMFDVMGFGKPMDQIPMLL
Rv0926c|M.tuberculosis_H37Rv LLPMALAGTCESIEQIRCMEIVDYATYDSAVVMFDVMGFGKPMDQIPMLL
MMAR_4582|M.marinum_M LLPMALAGTCQSIEQIRCMEIVDYATYDSAVVMFDVMGFGKPLDEIPMLL
MAV_1045|M.avium_104 LLPLALAGTCQSIQQIRCMEIVDYATYDSAAVMFDVMGFGKPLDDVPMLL
Mvan_4922|M.vanbaalenii_PYR-1 LLPMALAGTCQSIQQIRCMEIINYDTYDSAPVMFDVMGFGGSLDETPMLL
Mflv_1824|M.gilvum_PYR-GCK LLPMALAGTCQSIQQIRCMEIINYDTYDSAAVMFDVMGFGGSLDETPMLL
MSMEG_5586|M.smegmatis_MC2_155 LLPLALAGTCQQIEQIRCMEIVDYATYDSATVMLDVMGFGKSLDETPMLL
TH_0599|M.thermoresistible__bu QLPLALAGACQHIEQIRCLEIVDYATYDSATVLFDVMGFGKPLDEIPLLL
MAB_4633|M.abscessus_ATCC_1997 LLPLALMGTCQRIDQVRCIEIVDYATYDSATVMFDVMGFGKPMEETPMLL
MUL_3685|M.ulcerans_Agy99 MVGMVLSGSCERVDEIRITESVDCSTYESAATQT-AMGFSQHPDTPGLAE
: :.* *:*: ::::* * :: **:** . .***. : :
Mb0949c|M.bovis_AF2122/97 QPGVLSLAWGSVVRQLAAGLGISLDGVEEMYVREPAPEAFNIASGHIPKG
Rv0926c|M.tuberculosis_H37Rv QPGVLSLAWGSVVRQLAAGLGISLDGVEEMYVREPAPEAFNIASGHIPKG
MMAR_4582|M.marinum_M QPGVLSLAWGSVVRQLAAGLGLSLDVVEEMYVREPAPHAFDIASGHIPQG
MAV_1045|M.avium_104 QPGVLSLAWGSVVRQLAAGLGVSLDEVTQQHVRVPAPEDFDIASGHIAKG
Mvan_4922|M.vanbaalenii_PYR-1 QPGVLSLAWGSVVRQLAAGLGIELDEVTETHLRVPAPEAFDIAAGRIEKG
Mflv_1824|M.gilvum_PYR-GCK QPGVLSLAWGSVVRQLAAGLDIELDEVTETHERVPAPESFDIAAGRIEEG
MSMEG_5586|M.smegmatis_MC2_155 QPGVLSLAWGSVVRQLAAGLGIELDAVTEEHTRVPAPEDFDIAAGHISEG
TH_0599|M.thermoresistible__bu QPGVLTMAWGSVVRQLAAGLGIELDEVREQYVREPAPEDFDIAAGHIPQG
MAB_4633|M.abscessus_ATCC_1997 QPGVLSLAWGSVVRQLAAGLGVELDEVTEVYEKLSAPEDFDISSGHIPAG
MUL_3685|M.ulcerans_Agy99 SVRVESEVFAESAAMMADAIGATLDKMTFDVTFTAATADTDLGFMKIPAG
. * : .:.. . :* .:. ** : .*. ::. :* *
Mb0949c|M.bovis_AF2122/97 SAAALRFEVLGLVDGVPAVVLEHVTRLRADLCPEWPQPAQPGGSYRIEIS
Rv0926c|M.tuberculosis_H37Rv SAAALRFEVLGLVDGVPAVVLEHVTRLRADLCPEWPQPAQPGGSYRIEIS
MMAR_4582|M.marinum_M SAAALRFEVLGLVDGAPVVVLEHVTRLREDLCPDWPQPAQPGGSYRIEIT
MAV_1045|M.avium_104 TAAALRFEVFGMVDGRPVVVLEHVTRLREDLCPDWPQPAQHGGSYRIEVT
Mvan_4922|M.vanbaalenii_PYR-1 TTAAIRFEVRGMKDGEVAVVLEHVTRLRDDLCPDWPQPAQHGGSYRIEIT
Mflv_1824|M.gilvum_PYR-GCK TTAAIRFEVRGMKDGNVAVILEHVTRLRDDLCPDWPQPAQHGGSYRIEVT
MSMEG_5586|M.smegmatis_MC2_155 TTAAMRFEVRGMVDGKPAVVLEHVTRLRDDLCPEWPQPAQEGGSYRVEVT
TH_0599|M.thermoresistible__bu SAAALRFEVQGMVDGHPAVVLEHVTRLRDDLRPDWPQPAQPGGSYRVEVT
MAB_4633|M.abscessus_ATCC_1997 TMAALHFEVRGIKDGRAVTVLEHFTRLREDLAPNWPQPAHEGGTYRVEIT
MUL_3685|M.ulcerans_Agy99 TVGSVYGYHRGWVGDRNVVSVGFNWTMGNHVVP--PKPLKHG--HVIQVF
: .:: * .. .. : . : .: * *:* : * : :::
Mb0949c|M.bovis_AF2122/97 GEPCYAMDICLSSRH----GDHNHAGLVATAMRIVNAIPAVVAAEPGIRT
Rv0926c|M.tuberculosis_H37Rv GEPCYAMDICLSSRH----GDHNHAGLVATAMRIVNAIPAVVAAEPGIRT
MMAR_4582|M.marinum_M GEPSYAMDLCLSSRR----GDHNHAGLVATAMRVVNAIPAVVAAPPGIRT
MAV_1045|M.avium_104 GEPSYAMDICLSSRK----GDHNHAGLVATAMRVVNAIPAVVAAPPGIVT
Mvan_4922|M.vanbaalenii_PYR-1 GEPSYALDLCLSSPN----GDHNHAGLVATAARVVNAIPAVIDAAPGIVT
Mflv_1824|M.gilvum_PYR-GCK GEPSYAMDLCLSSPN----GDHNHAGLVATAARVVNAIPAVVDSSPGIVT
MSMEG_5586|M.smegmatis_MC2_155 GEPSYALDLCLSSPY----GDHNHAGLVATAARVVNAIPAVFAAPPGIRT
TH_0599|M.thermoresistible__bu GEPCYTLDLRLSSPH----GDHNHAGLVATAARVVNAIPPVVAAPAGIRT
MAB_4633|M.abscessus_ATCC_1997 GEPSYLLDLGSFSAR----GDHNYANLIATAMRVVNAVPAVVAAEAGIRT
MUL_3685|M.ulcerans_Agy99 GLPNMRTVLHCLPPKDWTESGFMGLGMIYTAMPVTNAVPAVVAAKPGIVT
* * : . ... .:: ** :.**:*.*. : .** *
Mb0949c|M.bovis_AF2122/97 TLDLPLITGEGRYAAA--------
Rv0926c|M.tuberculosis_H37Rv TLDLPLITGEGRYAAA--------
MMAR_4582|M.marinum_M TLELPLVTGKGLYLPPAGAA----
MAV_1045|M.avium_104 TLDLPLITGRGLYRPE--------
Mvan_4922|M.vanbaalenii_PYR-1 ARELPPITGEGLYAKP--------
Mflv_1824|M.gilvum_PYR-GCK ARELPPITGKGLYANP--------
MSMEG_5586|M.smegmatis_MC2_155 TLDMPLITGKGLYAAR--------
TH_0599|M.thermoresistible__bu TLDLPWVSGTGRYLPPDRPEGTIR
MAB_4633|M.abscessus_ATCC_1997 TLDLPLITGKGRAV----------
MUL_3685|M.ulcerans_Agy99 LADLPPITGRAAL-----------
::* ::* .