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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4258 | - | - | 100% (467) | AMP-dependent synthetase and ligase |
| M. thermoresistible (build 8) | TH_3626 | - | 3e-53 | 34.15% (448) | PUTATIVE putative fatty-acid-CoA ligase |
| M. thermoresistible (build 8) | TH_3186 | - | 2e-49 | 34.75% (495) | PUTATIVE AMP-dependent synthetase and ligase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3591 | fadD3 | 1e-48 | 34.13% (501) | acyl-CoA synthetase |
| M. gilvum PYR-GCK | Mflv_2392 | - | 0.0 | 74.68% (462) | AMP-dependent synthetase and ligase |
| M. tuberculosis H37Rv | Rv3561 | fadD3 | 3e-49 | 34.33% (501) | acyl-CoA synthetase |
| M. leprae Br4923 | MLBr_02661 | - | 5e-39 | 30.54% (501) | acyl-CoA synthetase |
| M. abscessus ATCC 19977 | MAB_4055c | - | 6e-52 | 32.08% (477) | putative acyl-CoA synthetase |
| M. marinum M | MMAR_4793 | - | 0.0 | 69.44% (468) | acyl-CoA synthetase |
| M. avium 104 | MAV_0863 | - | 0.0 | 69.44% (468) | AMP-binding enzyme, putative |
| M. smegmatis MC2 155 | MSMEG_4876 | - | 0.0 | 69.51% (469) | acyl-CoA synthase |
| M. ulcerans Agy99 | MUL_0362 | - | 0.0 | 68.80% (468) | acyl-CoA synthetase |
| M. vanbaalenii PYR-1 | Mvan_4256 | - | 0.0 | 75.27% (461) | AMP-dependent synthetase and ligase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3591|M.bovis_AF2122/97 ----------------------MINDLRTVPAALDRLVR----QLPDHTA
Rv3561|M.tuberculosis_H37Rv ----------------------MINDLRTVPAALDRLVR----QLPDHTA
MAB_4055c|M.abscessus_ATCC_199 -----------------MTFRSPLPDVSIPDCSVYEYVFGDTGAEDSRIA
Mflv_2392|M.gilvum_PYR-GCK --------------------------------------------MSEPTA
Mvan_4256|M.vanbaalenii_PYR-1 --------------------------------------------MSDPWA
TH_4258|M.thermoresistible__bu --------------------------------------------MADRVA
MSMEG_4876|M.smegmatis_MC2_155 -----------------------------------------MRLMGESAV
MMAR_4793|M.marinum_M --------------------------------------------MTEPAA
MUL_0362|M.ulcerans_Agy99 MPGSAMTALPAPPLMYFRSSLLRILFASGDRIFSDCRDRREGRDVTEPAA
MAV_0863|M.avium_104 --------------------------------------------MTEPAA
MLBr_02661|M.leprae_Br4923 -----MKSESITSSRAPVEQIDARLTGQFESPSIASLVEAAAIRNPSAPA
. .
Mb3591|M.bovis_AF2122/97 LIAEDR--RFTSTELRDAVYGAAAALIALGVEPADRVAIWSPNTWHWVVA
Rv3561|M.tuberculosis_H37Rv LIAEDR--RFTSTELRDAVYGAAAALIALGVEPADRVAIWSPNTWHWVVA
MAB_4055c|M.abscessus_ATCC_199 LIDGLTGAQTTLGELRSQIDATAAGLAERGFGIGDVAAVFLPNCSAFAVV
Mflv_2392|M.gilvum_PYR-GCK LAFEDR--CLSLADIDALAAGMAVELQRRGVGAGSRVALMSSNRPEFVVA
Mvan_4256|M.vanbaalenii_PYR-1 LAFEDR--QYSLADLDALAGGMAAELHRRGVAAGSRVAVMSSNRPEFVVA
TH_4258|M.thermoresistible__bu LTFEDR--AYSAAELDALTGGTAAALAARGVCPGSRVAIMSSNRPEFVVA
MSMEG_4876|M.smegmatis_MC2_155 LAFGDR--EYTLTELDALAGGMAATLAQRGVGPGDRVAMMSSNRPEFVIA
MMAR_4793|M.marinum_M LVFEDR--GFSLPGLGAMADGLAAALRKQGVVAGDRVAVMSSNRPEFVAV
MUL_0362|M.ulcerans_Agy99 LVFEDR--GFSLPGLGAMADGLAAALRKQGVVAGDRVAVMSSNRPEFVAV
MAV_0863|M.avium_104 LVFEER--RFSVPELDALADGWAAALAKDGVTAGRRVAVMTSNRPEFLAV
MLBr_02661|M.leprae_Br4923 LVVTDNRIVVSYRDLLRLVDDLTVQLALGGLLPGDRVALCAASNIEFVVG
* : : :. * *. . .*: .. :
Mb3591|M.bovis_AF2122/97 CLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGL
Rv3561|M.tuberculosis_H37Rv CLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGL
MAB_4055c|M.abscessus_ATCC_199 LHGILRAGGTASTVNVLYTAEELAKQLIDSKAQLIFTVSPLLSR----AL
Mflv_2392|M.gilvum_PYR-GCK LRAIWRLGAAAVLLSPAWKQTEVGHAVALTEATHAVGDHPVLADAMP---
Mvan_4256|M.vanbaalenii_PYR-1 LRAIWRLGASAVLLSPAWKQAEVGHALSLTEPTHAVGDHPVLAGSMP---
TH_4258|M.thermoresistible__bu LRAIWSLGAAAVLLSPAWKRAEVDHALALTTPSHAVGDHPVLADLMP---
MSMEG_4876|M.smegmatis_MC2_155 LRAIWRLGAAAVLISPAWKTTEIAHALELTRANHAVGDQPLLAEHLP---
MMAR_4793|M.marinum_M LNAIWCLGASAVLISPAWKRAEVDHALALTGPAHAAGDHPVLAGLMP---
MUL_0362|M.ulcerans_Agy99 LNVIWCLGASAVLISPAWKRAEVDHALALTGPAHAAGDHPVLAGLMP---
MAV_0863|M.avium_104 LLAIWRLAATAVLISPAWKRDEVEHALALTDPGHAVGDHPVLAGLMP---
MLBr_02661|M.leprae_Br4923 LLAASRAGLIVVPLDPALPVNEQCIRSQAAGVRVTLVDSLALEGVSDQRA
. . :. * : *
Mb3591|M.bovis_AF2122/97 DRAALPALRHVVRVPVEADDGTWDEFIATGAGALDAVAARAAAVAPQDVS
Rv3561|M.tuberculosis_H37Rv DRAALPALRHVVRVPVEADDGTWDEFIATGAGALDAVAARAAAVAPQDVS
MAB_4055c|M.abscessus_ATCC_199 EAAEIAGIDAAGVITVDPVEG---RLSLADIARPDLAPPQVTFDPATHLA
Mflv_2392|M.gilvum_PYR-GCK ------------------------MLSLDDEIAPRDP-EAAPDPDAGADA
Mvan_4256|M.vanbaalenii_PYR-1 ------------------------MLSLDEEIAPVAHGAVQPAPTPDADA
TH_4258|M.thermoresistible__bu ------------------------MLHLDEPVTADPDGAGRPVPPEDADA
MSMEG_4876|M.smegmatis_MC2_155 ------------------------MVHLDEPITPGER--PGPAVAPDADA
MMAR_4793|M.marinum_M ------------------------MLHLDEPITPAAP--LPGAPRRAGDA
MUL_0362|M.ulcerans_Agy99 ------------------------MLHLDEPITPAAP--LPGAPRRAGDA
MAV_0863|M.avium_104 ------------------------MLHLDEPVPPAQP--TAGAPPRAGDA
MLBr_02661|M.leprae_Br4923 ATMRYWPIAVSYGSVTGASEGS--LLVHLDDTAALHPVTSTPDGLRHDDA
. :
Mb3591|M.bovis_AF2122/97 DILFTSGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHN
Rv3561|M.tuberculosis_H37Rv DILFTSGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHN
MAB_4055c|M.abscessus_ATCC_199 VLPYSSGTTGKAKGVMLTHHNLVANIAQAKHLYGVQRGDRVLAVLPFFHI
Mflv_2392|M.gilvum_PYR-GCK VFVFSSGTTGMPKAVRHTHASLAVAIRHWRDALGLTAADRMQVMTPPSHI
Mvan_4256|M.vanbaalenii_PYR-1 VFVFSSGTTGMPKAVRHTHASLAVAVRHWRAALGLTSADRMQVMTPPSHI
TH_4258|M.thermoresistible__bu LFVFSSGTTGMPKAVRHTHGALRTAVRHWRDALGLTAADRMQIMTPPSHI
MSMEG_4876|M.smegmatis_MC2_155 LFVFSSGTTGMPKAVRHSHAGFAAAIEHWRDALGLTAADRMQIMTPPSHI
MMAR_4793|M.marinum_M LLVFSSGTTGLPKAVRHTHASLNAAIGHWRDALGLTERDRIQIVTPPSHI
MUL_0362|M.ulcerans_Agy99 LLVFSSGTTGLPKAVRHTHASLNAAIGHWRDALGLTERDRIQIVTPPSHI
MAV_0863|M.avium_104 VLVFSSGTTGLPKAVRHTHASLDEAVRHWREALRLTRRDRIQVATPPSHI
MLBr_02661|M.leprae_Br4923 MIMFTGGTTGLPKMVPWTDGNIAGSVHAIITAYQLGPQDATVVVMPLYHG
: ::.**** .* * :. : * * *
Mb3591|M.bovis_AF2122/97 FGYKAGILACLQTG--ATLIPHVTFDPLHALRAIERHRITVLPGPPTIYQ
Rv3561|M.tuberculosis_H37Rv FGYKAGILACLQTG--ATLIPHVTFDPLHALRAIERHRITVLPGPPTIYQ
MAB_4055c|M.abscessus_ATCC_199 YGLVVLLNVQLKLG--AELVILPRFELDTFLGSIANYRVDHVFVAPPVAV
Mflv_2392|M.gilvum_PYR-GCK LGLLN-IIMALDTG--AWIRLHRRFDIDAMLRHIESDRITIEMAVAPIAL
Mvan_4256|M.vanbaalenii_PYR-1 LGLLN-IVMALDTG--AWIRLHRRFDIDAMLRHIESDRITIEMAVAPIAL
TH_4258|M.thermoresistible__bu LGLLN-IVMALDTG--TWIRLHRRFDIDRMLHHIQADRITIEMAVAPIAL
MSMEG_4876|M.smegmatis_MC2_155 LGLLN-IAMVLDTG--AWMRLHPRFDVETMLRHIESDGITIEMAVAPIAL
MMAR_4793|M.marinum_M LGLLN-IVTALRTG--VRVRLHRRFDIDQMLAHIESDRITVEMAVAPIAL
MUL_0362|M.ulcerans_Agy99 LGLLN-IVAALRTG--VRVRLHRRFDIDQMLAHIESDRITVEMAVAPIAL
MAV_0863|M.avium_104 LGLLN-LLTALKTG--ACVRLHPRFDIDKVLHHIESDRVTVEMAVAPIAL
MLBr_02661|M.leprae_Br4923 HGLIAALLSTLASGGVVLLPARARFSARTFWDDIDAVAATWYTAAPAIHR
* : * * . : *. * ..:
Mb3591|M.bovis_AF2122/97 SLLDHPARKDFDLS--SLRFAVTGAATVPVVLVERMQSELDIDIVLTAYG
Rv3561|M.tuberculosis_H37Rv SLLDHPARKDFDLS--SLRFAVTGAATVPVVLVERMQSELDIDIVLTAYG
MAB_4055c|M.abscessus_ATCC_199 VLAKHPDVDKYDVS--CLRSVFSGAAPLDEQLGNAVAARLNCRVSQG-YG
Mflv_2392|M.gilvum_PYR-GCK ALSAHPRLEDHDLS--SLRYIMWCATPVTQSVAEAVTARTGVTWVTA-YG
Mvan_4256|M.vanbaalenii_PYR-1 ALSAHPGLEEHDLS--SLRYIMWCATPVTQTVAEAVSARTGATWVTA-YG
TH_4258|M.thermoresistible__bu ALAGHPGLESYDLS--SLRYIMWCATPVTQSVADAVTARTGVGWIAA-YG
MSMEG_4876|M.smegmatis_MC2_155 ALAAHPGLERFDLS--SLRFVMWCATPVTRSVAEDITARAGIRWLTA-YG
MMAR_4793|M.marinum_M AMASHPNLESYDLS--SLRFIMWGATPVSAGIAETVTNRTGIGWVPA-YG
MUL_0362|M.ulcerans_Agy99 AMASHPNLESYDLS--SLRFIMWGATPVSAGIAETVTNRTGIGWVPA-YG
MAV_0863|M.avium_104 AIASHPDLESYDLS--SLRYIVWGATPVNAEVAQTVTRRTGVGWLPA-YG
MLBr_02661|M.leprae_Br4923 ILLELASTQSFRSKRAKLRFIRSCSAPLTQETAQALREEFLAPVICA-FG
: . . . . ** ::.: : : . :*
Mb3591|M.bovis_AF2122/97 LTEANGMGTMCRPEDDAVTVATTCGRPFA----DFELRIAD---------
Rv3561|M.tuberculosis_H37Rv LTEANGMGTMCRPEDDAVTVATTCGRPFA----DFELRIAD---------
MAB_4055c|M.abscessus_ATCC_199 MTELSPVSHLIPPDRPDIPLN-SVGIPVP----NSENKIIDTETGDEIEI
Mflv_2392|M.gilvum_PYR-GCK ASELP----VISCNDLQHARLDTVGRAVT----GVGIRIVSLQTGEVL--
Mvan_4256|M.vanbaalenii_PYR-1 ASELP----VISCNDLQDARLDTVGRAVA----GVDIRIVSLESGAPL--
TH_4258|M.thermoresistible__bu TTELP----VIACNPLQGGRLDTVGRPVP----GVQVRIVSLDTGAPV--
MSMEG_4876|M.smegmatis_MC2_155 TTELP----VIACNPLDDTRIETVGKPVR----GVRVRIA----------
MMAR_4793|M.marinum_M TTELP----VIACSPLRGARLDTVGRVLP----GVDLRVVSIETGERV--
MUL_0362|M.ulcerans_Agy99 TTELP----VIACSPLRGARLDTVGRVLP----GVDLRVVSTETGERV--
MAV_0863|M.avium_104 TTELP----VIACNPIEDARLDTVGRPVP----GVEVRVVSLESGEPA--
MLBr_02661|M.leprae_Br4923 MTEATHQVTTTNIKWFGQGENPTVTNGLVGQSTGVQIRIVGSDGQPLP--
:* . : . . ::
Mb3591|M.bovis_AF2122/97 -------DGEVLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQA
Rv3561|M.tuberculosis_H37Rv -------DGEVLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQA
MAB_4055c|M.abscessus_ATCC_199 PAEGESAPGELLVRGPNVMAGYLGNEEATAATIEPDGFLHTGDIAVVRAD
Mflv_2392|M.gilvum_PYR-GCK ---GAGEEGEIQVRSDSAMAGYLPDQWTAQAFS--DGWYRTGDVGTLDGE
Mvan_4256|M.vanbaalenii_PYR-1 ---GPGDEGEIQVRSDSAMAGYLPDHWTADAFC--DGWYRTGDVGSLDAD
TH_4258|M.thermoresistible__bu ---GPGEEGEVQARSASVMAGYLPDQ--PGAFV--EGWYRTGDVGYLDTD
MSMEG_4876|M.smegmatis_MC2_155 ------DTGEIQVCSPSAMCGYLPESATGGAFD--DGWYRTGDIGFLDDD
MMAR_4793|M.marinum_M ---GPGEVGEIQARSHSLMAGYLPAAATAEVMS--QGWYRTGDIGSLDAA
MUL_0362|M.ulcerans_Agy99 ---GPGEVGEIQARSHLLMAGYLPAAATAEVMS--QGWYRTGDIGSLDAA
MAV_0863|M.avium_104 ---GAGEVGEIQARSASLMAGYLPGEATGEAIR--DGWYRTGDAGWLDTG
MLBr_02661|M.leprae_Br4923 ----PDTVGEVWLRGSTVVRGYLGDPAITAANFT-HGWLRTGDLGSLSVT
**: . : *** . .*: :*** . :
Mb3591|M.bovis_AF2122/97 GNLRINDRLKDMYICGGFNVYPAEVEQVLARMDGVADAAVIGVPDQRLGE
Rv3561|M.tuberculosis_H37Rv GNLRITDRLKDMYICGGFNVYPAEVEQVLARMDGVADAAVIGVPDQRLGE
MAB_4055c|M.abscessus_ATCC_199 GVVTIVDRLKELIKYKGYQVPPAELEALLLTHPGIGDAAVIGVPDPSSGE
Mflv_2392|M.gilvum_PYR-GCK GWLRITDRAKEMIKVRGFQVAPAEVEAVLHGHPAVEDCAVFGIP-AADGE
Mvan_4256|M.vanbaalenii_PYR-1 GWLRITDRAKEMIKVRGFQVAPAEVEAVLHGHPAVEDCAVFGVP-AADGE
TH_4258|M.thermoresistible__bu GWLRLTDRAKDMVKVRGFQVAPAEVEAVLHEHPAVDDCAVFGVP-SPDGE
MSMEG_4876|M.smegmatis_MC2_155 GYLHVTDRAKEMVKVRGFQVAPAEVEAVLHGHPAVADCAVFGEPHDTDGE
MMAR_4793|M.marinum_M GWLRVTDRLKEMIKVRGFQVAPAEIEAVLHGHPAVRDCAVFGVPDGANGE
MUL_0362|M.ulcerans_Agy99 GWLRVTDRLKEMIKVRGFQVAPTEIEAVLHGHPAVRDCAVFGVPDGANGE
MAV_0863|M.avium_104 GWLRITDRLKEMIKVRGFQVAPAEIDAVLQGHPAVADCAVFGVPDGLNGE
MLBr_02661|M.leprae_Br4923 GDLRIRGRIKELINRSGEKISPERVEGVLASHHNVMEVAVFGDPDKVYGE
* : : .* *:: * :: * .:: :* : : **:* * **
Mb3591|M.bovis_AF2122/97 VGRAFVVARPGTGLDEASVIAYTREHLANFKTPRSVRFVDVLPRNAAGKV
Rv3561|M.tuberculosis_H37Rv VGRAFVVARPGTGLDEASVIAYTREHLANFKTPRSVRFVDVLPRNAAGKV
MAB_4055c|M.abscessus_ATCC_199 IPKAFVVR-TDDDLTDEAVMAFVEQKVAPHKRIRQVEFIDAIPKSAAGKI
Mflv_2392|M.gilvum_PYR-GCK AIVAAVTL--GHPVDTDELADLVADRLASYKRPSRVVVVDEIPRLPSGKV
Mvan_4256|M.vanbaalenii_PYR-1 AIVAAVAA--SGPLDTDDLVALVAERLAGYKRLSQVFVVDEIPRLPSGKV
TH_4258|M.thermoresistible__bu ALVAAVTR--RGEVSADELLALVGERLASYKRPSRVVFVPEIPRLPSGKV
MSMEG_4876|M.smegmatis_MC2_155 AVVAAVAT--CAEVSAEELIDLVGARLASYKRPRRIEFVTEIPRLPSGKV
MMAR_4793|M.marinum_M AVVAAVAA--RTPVGDAELRARVAASLASYKRLSRIVFVPDIPRLPSGKV
MUL_0362|M.ulcerans_Agy99 AVVVAVAA--RTPVDAAELRARVAASLASYKRLSRIVFVPDIPRLPSGKV
MAV_0863|M.avium_104 AVVAAVAV--SAPVDVTELTALVRQKLASYKHLSRVVVVPEIPRLPSGKV
MLBr_02661|M.leprae_Br4923 TVTAVIVPREVIAPTPSELAVFCRDRLAAFEVPTRFQEASALPHTAKGSL
. :. : :* .: . :*: . *.:
Mb3591|M.bovis_AF2122/97 SKPQLRELG-----------------
Rv3561|M.tuberculosis_H37Rv SKPQLRELG-----------------
MAB_4055c|M.abscessus_ATCC_199 LRKDLRARI-----------------
Mflv_2392|M.gilvum_PYR-GCK LRRVLRERAMGAGAKSGGF-------
Mvan_4256|M.vanbaalenii_PYR-1 LRRVLRERAMSARAESGGFGGRPSDQ
TH_4258|M.thermoresistible__bu LRRVLKER---HGCPSDG--------
MSMEG_4876|M.smegmatis_MC2_155 LRRVLKER---HGRPSDG--------
MMAR_4793|M.marinum_M LRRALKEL---YGCASDS--------
MUL_0362|M.ulcerans_Agy99 LRRALKEL---YGCTSDS--------
MAV_0863|M.avium_104 LRRVLKER---HGCTSDS--------
MLBr_02661|M.leprae_Br4923 DRRAVAEQFAHRG-------------
: :