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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4255 | - | - | 100% (448) | putative PE-PPE, C-terminal domain protein |
| M. thermoresistible (build 8) | TH_3724 | - | 4e-14 | 27.49% (331) | PUTATIVE putative PE-PPE, C-terminal domain protein |
| M. thermoresistible (build 8) | TH_4159 | - | 7e-14 | 23.58% (458) | PUTATIVE PE-PPE, C-terminal domain protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2640 | PPE42 | 6e-10 | 29.84% (191) | PPE family protein |
| M. gilvum PYR-GCK | Mflv_3378 | - | 2e-07 | 28.36% (268) | hypothetical protein Mflv_3378 |
| M. tuberculosis H37Rv | Rv2608 | PPE42 | 7e-10 | 29.84% (191) | PPE family protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4141 | - | 9e-13 | 27.19% (320) | PE/PPE family protein |
| M. marinum M | MMAR_0382 | - | 2e-14 | 30.77% (182) | PE-PGRS family protein |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1176 | - | 9e-53 | 34.77% (440) | hypothetical protein MSMEG_1176 |
| M. ulcerans Agy99 | MUL_1034 | - | 2e-12 | 26.91% (249) | PE family protein |
| M. vanbaalenii PYR-1 | Mvan_4081 | - | 2e-58 | 41.47% (340) | hypothetical protein Mvan_4081 |
CLUSTAL 2.0.9 multiple sequence alignment
TH_4255|M.thermoresistible__bu -------------------------------------------VSSRQVL
Mvan_4081|M.vanbaalenii_PYR-1 --------------MSKVRHRIGSAACGVAALGMAITVGGVAATQPASIS
Mb2640|M.bovis_AF2122/97 ----------------MNFAVLPPEVNSARIFAGAGLGPMLAAASAWDGL
Rv2608|M.tuberculosis_H37Rv ----------------MNFAVLPPEVNSARIFAGAGLGPMLAAASAWDGL
MMAR_0382|M.marinum_M ----------------MSYVRTIPEFLST-------------AAADIGGI
MUL_1034|M.ulcerans_Agy99 ----------------MSYVLTAPDLLAS-------------AATDVDGI
MSMEG_1176|M.smegmatis_MC2_155 MSGITQNVREATMAIRDFRRACVPALVGGVALTTALGVGAVATAPAPAHV
MAB_4141|M.abscessus_ATCC_1997 ----------MAGQYSVPGKRHSLRRYVATITAVAATCTVLAPLAMESRT
Mflv_3378|M.gilvum_PYR-GCK -----------MHSALRPYVTTGLALVGTSVIALAPIAPPAPAFGGATVA
TH_4255|M.thermoresistible__bu TEAIELSALIAVGSSTNPAGTGVVNFFQSRFN-------------PPGTD
Mvan_4081|M.vanbaalenii_PYR-1 ASPVDLTALIVVGSSTHPDPTGNEDFFGGKFNQAPYNPGG-----QPGPD
Mb2640|M.bovis_AF2122/97 AEELHAAAGSFASVTTGLAGDAWHGPASLAMTRAASPYVGWLNTAAGQAA
Rv2608|M.tuberculosis_H37Rv AEELHAAAGSFASVTTGLAGDAWHGPASLAMTRAASPYVGWLNTAAGQAA
MMAR_0382|M.marinum_M GSALTDASSAAAGPTTNLLAAAAD-EVSAVVSKVFGGYG-----------
MUL_1034|M.ulcerans_Agy99 AATLQVANSAAAALTSGLLAAAQD-EVSAAIAKVFSAYG-----------
MSMEG_1176|M.smegmatis_MC2_155 ASDVGLKALITHGSATNWNADGIDKFYGLDWNEKYGPTVVS--------Q
MAB_4141|M.abscessus_ATCC_1997 IASTLASYVIGIGGNNDGASANIPRKLGGAYSVDYHPVSYPG-AIWPVSG
Mflv_3378|M.gilvum_PYR-GCK KQVTQDVTLSARVVTLNPTPDALEMGEQLQGSICGGNGTPCYEVEYAPIW
TH_4255|M.thermoresistible__bu VRTVNFLTGPLGIYAALVS-TDESD--VVLSSGWGAANASALLSWFNHTD
Mvan_4081|M.vanbaalenii_PYR-1 LIGLDFRGGAAAIEQALQENSGEDN--AVLSSGWGAANASLVLNRLDRAG
Mb2640|M.bovis_AF2122/97 QAAGQARLAASAFEATLAATVSPAM--VAANRTRLASLVAANLLGQNAPA
Rv2608|M.tuberculosis_H37Rv QAAGQARLAASAFEATLAATVSPAM--VAANRTRLASLVAANLLGQNAPA
MMAR_0382|M.marinum_M LSAQAVLTQASAFHDEFTELLANAG--GIYAQAEVDN--AEALTN----A
MUL_1034|M.ulcerans_Agy99 QEYQAAIAQASAFHTEFTRALAAAG--AAYAQAEAAN--ASLITAGVSDA
MSMEG_1176|M.smegmatis_MC2_155 FSLFPYNVNPDNLKAALRNNVGDPEPDLVLTSGRGSGAATVTMLLLLNSG
MAB_4141|M.abscessus_ATCC_1997 LTAPTFKTSVAQGRTNLNDEIVTAG--NQPITIVGYSLGAVVVSKSHSDL
Mflv_3378|M.gilvum_PYR-GCK TGPGYFGLGVEALREALTGNPGEET--TIFAFSEGAVVASQWLEKHLEDP
: : :
TH_4255|M.thermoresistible__bu PAALA----GNLWVLDNNVARPNGG----WGTRYPVFALIGVNPIPTP--
Mvan_4081|M.vanbaalenii_PYR-1 DPALP----KSLFILDNNVSRPDGG----FGTRYPLFALIGVNPFPSPT-
Mb2640|M.bovis_AF2122/97 IAAAE----AEYEQIWAQDVAAMFG----YHSAASAVATQLAPIQEGLQQ
Rv2608|M.tuberculosis_H37Rv IAAAE----AEYEQIWAQDVAAMFG----YHSAASAVATQLAPIQEGLQQ
MMAR_0382|M.marinum_M VGEFS----EPFIQLWDPSYTYVG-----SNIATGPNPQPNEPSLT----
MUL_1034|M.ulcerans_Agy99 LTAIT----TPIQSLLGPAAIGTGG----AGSAGALTAVSSTLMAD----
MSMEG_1176|M.smegmatis_MC2_155 RPEDRELVLNTRWILDNSVNRPNGG----YGSRYIPFSILGVYPWPTP--
MAB_4141|M.abscessus_ATCC_1997 LQRYPGGNPNIQFVLMGSANTPNGG----IFARFPWLKIPLADIESNG--
Mflv_3378|M.gilvum_PYR-GCK EAYPAP--ENLTFVVIGNPARKYGGSGTIWGRQWPTSPYQVIDVAQQYDP
:
TH_4255|M.thermoresistible__bu --------------------------------------------------
Mvan_4081|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2640|M.bovis_AF2122/97 QLQNVLAQLASGNLGSGNVGVGNIGNDNIGNANIGFGNRGDANIGIGNIG
Rv2608|M.tuberculosis_H37Rv QLQNVLAQLASGNLGSGNVGVGNIGNDNIGNANIGFGNRGDANIGIGNIG
MMAR_0382|M.marinum_M --------------------------------------------------
MUL_1034|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1176|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4141|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3378|M.gilvum_PYR-GCK TVDMPVNNLNVLATLNATMGFFTNHLGRGYSDVDIDDPANSRWEEDGIEY
TH_4255|M.thermoresistible__bu ---------------------------------------EIDGVQVIDIG
Mvan_4081|M.vanbaalenii_PYR-1 ---------------------------------------DTAARAVVDIA
Mb2640|M.bovis_AF2122/97 DRNLGIGNTGNWNIGIGITGNGQIGFGKPANPDVLVVGNGGPGVTALVMG
Rv2608|M.tuberculosis_H37Rv DRNLGIGNTGNWNIGIGITGNGQIGFGKPANPDVLVVGNGGPGVTALVMG
MMAR_0382|M.marinum_M ------------------------------------------PEFALIMG
MUL_1034|M.ulcerans_Agy99 ------------------------------------------PVVALIMG
MSMEG_1176|M.smegmatis_MC2_155 ---------------------------------------TDEGVDIVDVG
MAB_4141|M.abscessus_ATCC_1997 -------------------------------------AWEPDQFKTKVIN
Mflv_3378|M.gilvum_PYR-GCK VFVPAKTLPLVEPLRWVGLGQLADELTPGLQYLIEQGYNRDDRITGTTID
:
TH_4255|M.thermoresistible__bu YQYDANSNAPAYFLNPIAD-------------------------------
Mvan_4081|M.vanbaalenii_PYR-1 YQYNYNSNAPADLLNLVAH-------------------------------
Mb2640|M.bovis_AF2122/97 GTDSLLSLPNIPLLEYAAR-------------------------------
Rv2608|M.tuberculosis_H37Rv GTDSLLPLPNIPLLEYAAR-------------------------------
MMAR_0382|M.marinum_M GTFDPQPFP-LYVTTINNA-------------------------------
MUL_1034|M.ulcerans_Agy99 GTSVPLPGP-GYVSDINNN-------------------------------
MSMEG_1176|M.smegmatis_MC2_155 YEYAWNSSAPAYVTNVVAL-------------------------------
MAB_4141|M.abscessus_ATCC_1997 TEYDTYGDFPAYFNPLALAN------------------------------
Mflv_3378|M.gilvum_PYR-GCK APEKSWSYAPINFLEAIANIPYYSVAGTNRFANAMRASGSWWVYTPTNVL
.
TH_4255|M.thermoresistible__bu ------------------LNS--LVAYAQRRLHQSELYLPVQDDGTIVDA
Mvan_4081|M.vanbaalenii_PYR-1 ------------------VNS--LVAYLYGYREQSEIDLPVDVDGRPTVS
Mb2640|M.bovis_AF2122/97 ------------------FITPVHPGYTATFLETPSQFFPF-TGLNSLTY
Rv2608|M.tuberculosis_H37Rv ------------------FITPVHPGYTATFLETPSQFFPF-TGLNSLTY
MMAR_0382|M.marinum_M ------------------FIQPFFPGATSVGLSYPAQFWPLTSGL---TL
MUL_1034|M.ulcerans_Agy99 ------------------YIQPLFSGAIPQALFTPEQFWPVTPGLGNLTF
MSMEG_1176|M.smegmatis_MC2_155 ------------------LNS--IIAYAYRYKSQAFTGLPVDPALGIDPV
MAB_4141|M.abscessus_ATCC_1997 ---------------SIAAIQYAHPDAYYDRIDPAALDDPDNPNVVKTVQ
Mflv_3378|M.gilvum_PYR-GCK GWDPANPEMTRAFVDFLVAIPSISTPMGMTADWWARANLPMNEGCTGFPP
. *
TH_4255|M.thermoresistible__bu TDTVVECPDTCRVVIGWEDD------------------------------
Mvan_4081|M.vanbaalenii_PYR-1 CGGANTCAVLAGGVDALPCDDAR---------------------------
Mb2640|M.bovis_AF2122/97 DVSVAQGVTNLHTAIMAQLAAGN---------------------------
Rv2608|M.tuberculosis_H37Rv DVSVAQGVTNLHTAIMAQLAAGN---------------------------
MMAR_0382|M.marinum_M NQSVAEGVIDLNNALSVQINGGQ---------------------------
MUL_1034|M.ulcerans_Agy99 NQSVAQGVTLLNDAINTQLALGN---------------------------
MSMEG_1176|M.smegmatis_MC2_155 TG---EPKLEKGYHYIVEVDG-----------------------------
MAB_4141|M.abscessus_ATCC_1997 GNTTYYLVRAEHLPLLQPLRDLT---------------------------
Mflv_3378|M.gilvum_PYR-GCK CDNPAGITDQMFKVQLWDFFAPGGFTFTDPITPEYNPISDTEAFWGQELG
TH_4255|M.thermoresistible__bu ---------------------------------------------GTPQY
Mvan_4081|M.vanbaalenii_PYR-1 ----------------------------------------CAIPSGERVL
Mb2640|M.bovis_AF2122/97 ----------------------------------------EVVVFGTSQS
Rv2608|M.tuberculosis_H37Rv ----------------------------------------EVVVFGTSQS
MMAR_0382|M.marinum_M ----------------------------------------HVINFGFSQS
MUL_1034|M.ulcerans_Agy99 ----------------------------------------KVVAFGYSQS
MSMEG_1176|M.smegmatis_MC2_155 --------------------------------------------TVTKEP
MAB_4141|M.abscessus_ATCC_1997 ----------------------------------------NPIGASFVLD
Mflv_3378|M.gilvum_PYR-GCK LTGDKVEWYGETVHPEPFGETKGFLDFLISTPEGIKTPTLQDQLNAFRNL
TH_4255|M.thermoresistible__bu AEIKKVGDTTYVTYLSNGLPLVQPLRLLG-PVGSTLADVL-----EPIAT
Mvan_4081|M.vanbaalenii_PYR-1 AYVTTRGNTTYVTYTTDELPLTRLIRAV---LGDTVADAS-----APLLK
Mb2640|M.bovis_AF2122/97 ATIATFEMRYLQSLPAHLRPGLDELSFTL-TGNPNRPDGG-----ILTRF
Rv2608|M.tuberculosis_H37Rv ATIATFEMRYLQSLPAHLRPGLDELSFTL-TGNPNRPDGG-----ILTRF
MMAR_0382|M.marinum_M AVVATQEMQRLMALPVGMRPDPSDLSFVL-AGNPATPNGG-----IFTRF
MUL_1034|M.ulcerans_Agy99 ATIVNNEILALMAMGTGA-PDPGDLSFIM-VGAPNNPDGG-----LLARF
MSMEG_1176|M.smegmatis_MC2_155 LKSLGNTNTAYVTYRADGLPMLQPLRDFGGQFGNAVADLL-----QPALK
MAB_4141|M.abscessus_ATCC_1997 AIEPTLRVFIDMAYDRDTGPGTTTQFSFFTPSKNIVDAFN-----KLPTA
Mflv_3378|M.gilvum_PYR-GCK ADGLTTTWNPFVPKSYVWNPDMTPFAYLARPLAKILCPTCNAVDPFMPED
. *
TH_4255|M.thermoresistible__bu VLVNAGYPDNDP-IAN-PDRYVPGRFLPP--PHVVVTALRQLPEAIQDGL
Mvan_4081|M.vanbaalenii_PYR-1 LIVDSAYYDGNP-ISSDPSRYRPARLMPS--LGELIDTASKVPGAIREGL
Mb2640|M.bovis_AF2122/97 G-FSIPQLGFTLSGATPAD-AYPTVDYAF--QYDGVNDFPKYPLNVFATA
Rv2608|M.tuberculosis_H37Rv G-FSIPQLGFTLSGATPAD-AYPTVDYAF--QYDGVNDFPKYPLNVFATA
MMAR_0382|M.marinum_M PGMHIPFVDLTFTSPTPPDTPYPTTIYAT--QYDPTSDFPRYPLNILSDL
MUL_1034|M.ulcerans_Agy99 PGFYIPFLDVSFNGATPAANPYPTSIFTA--QYDGIAHAPQYRLNILSDI
MSMEG_1176|M.smegmatis_MC2_155 VIVDASYPGGDP--VANPDRYITASLFTP--PDVAIKAIQTLPSAIHQGV
MAB_4141|M.abscessus_ATCC_1997 IAEGAHNVENGLAGATPKQSASPEKPASPPVPQPGPTNPGSATTQIPAPE
Mflv_3378|M.gilvum_PYR-GCK WKVGLDVYPGAYIPPSVKDQYDPETGKYIGDPVDGLTDAEIAEWNEKAGL
.
TH_4255|M.thermoresistible__bu TRLHRAGSGSTGPDPAPETGRTESTRFAEAPGAV-----IRTTGGSVAAN
Mvan_4081|M.vanbaalenii_PYR-1 ETLSDNDSRQS-SEPARET----------------------VTAQTVEEA
Mb2640|M.bovis_AF2122/97 NAIAGILFLHSGLIALPPDLASGVVQPVSSPDVL--TTYILLPSQDLPLL
Rv2608|M.tuberculosis_H37Rv NAIAGILFLHSGLIALPPDLASGVVQPVSSPDVL--TTYILLPSQDLPLL
MMAR_0382|M.marinum_M NTLMS-LGQHE---LYPNLDVSNAVQLPTSPDYTGNTTYYMFMTKNLPLL
MUL_1034|M.ulcerans_Agy99 NAIMGYFYVHG---NYPDLMSGQAIQLPTSPGYTGNTDYYMYLTQDLPLV
MSMEG_1176|M.smegmatis_MC2_155 EDFKKDLGLTKTKAPAADERQSEPKPVEEQSAPQRDDDTTEAPSAAVAVS
MAB_4141|M.abscessus_ATCC_1997 APTPSVVSLSTAEPPAPPASAKAADPTAISVSTAGASTARDQDFQPDTKP
Mflv_3378|M.gilvum_PYR-GCK NDIVDETTDGTEETEESGDVSEDPADADTSLLSARSMATVDESSEDTGAS
TH_4255|M.thermoresistible__bu GAERLAAAEPTPS--VDDRRPTRRVSPNFSTRVGSVSGSAEDPAVAEDST
Mvan_4081|M.vanbaalenii_PYR-1 GHRDDDPAAPGED--DDDATEVVQDDDEAAEVGQDDGAVDADPAVDESAG
Mb2640|M.bovis_AF2122/97 VPLRAIPLLGNPL--ADLIQPDLRVLVELGYDRT----AHQDVPSPFGLF
Rv2608|M.tuberculosis_H37Rv VPLRAIPLLGNPL--ADLIQPDLRVLVELGYDRT----AHQDVPSPFGLF
MMAR_0382|M.marinum_M EPVRAIPFIGNPI--ADFIQPDLRVLVDLGYSDWGSGQDYANVPTPATLF
MUL_1034|M.ulcerans_Agy99 QPIRDIPYAGPPL--ADLIQPQLRVLVDLGYSDYGPGLSYADVPTPAGLL
MSMEG_1176|M.smegmatis_MC2_155 SKLATESAATSVK--SVADSGDVKDVKDVKAVEDTKKATDKRVRPRPLRK
MAB_4141|M.abscessus_ATCC_1997 DPKSTPPPTKDSVGEADKSKNTLKPTLRLPKLPVAQPGTAPKSPKFPSLK
Mflv_3378|M.gilvum_PYR-GCK DKKTDVISAAVQDLVDTFDKTPAAEDTEQGAETPAGSEEPTQPQDETPAA
TH_4255|M.thermoresistible__bu SVPKTGDATPRRVRGVLQR----------------PTVGAHERPAGERRE
Mvan_4081|M.vanbaalenii_PYR-1 AEDSVGNDDAVAAADPEGG----------------LTTDAADGSGEESSE
Mb2640|M.bovis_AF2122/97 PDVDWAEVAADLQQGAVQG---------VNDALSGLGLPPPWQPALPRLF
Rv2608|M.tuberculosis_H37Rv PDVDWAEVAADLQQGAVQG---------VNDALSGLGLPPPWQPALPRLF
MMAR_0382|M.marinum_M PIPNPFVIGTDLVIGAVHG----STALAVDLGLLPASALPNAYPYLPSLD
MUL_1034|M.ulcerans_Agy99 SVPNPFAVSYYLLKGSLQAPYGAAVEIGVEAGLLGPESFPDTYPWVPSLN
MSMEG_1176|M.smegmatis_MC2_155 LVDRVTKALTPKATRPAKTS--------------KPSTGTESGGASTGQS
MAB_4141|M.abscessus_ATCC_1997 NHLKSVPGLSEKKNPAADAS--------------SKHSQPANAPAHTSDK
Mflv_3378|M.gilvum_PYR-GCK DADDDAGVDAEPVTTPRKPSSTTKSDVDASESADADATTSGTAGTSESSE
.
TH_4255|M.thermoresistible__bu TGHTGTPGGADPTE----------------------------------
Mvan_4081|M.vanbaalenii_PYR-1 ------------------------------------------------
Mb2640|M.bovis_AF2122/97 ------------------------------------------------
Rv2608|M.tuberculosis_H37Rv ------------------------------------------------
MMAR_0382|M.marinum_M TDLNFFLGQPGVTDISLVTNAIGPVLQRLP-AINPG------------
MUL_1034|M.ulcerans_Agy99 PGLNFYLGQPSVTLLSLLSGGLGDIFHLIPPPVFP-------------
MSMEG_1176|M.smegmatis_MC2_155 DSGDAKSGDSES------------------------------------
MAB_4141|M.abscessus_ATCC_1997 TSDHASETGRGAA-----------------------------------
Mflv_3378|M.gilvum_PYR-GCK SEKSDTSSDSSASDSSASDSASSSDSSGSGAGSSGSGGSAGSGGGSDD