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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2649 | - | - | 100% (394) | cytochrome P450 superfamily protein |
| M. thermoresistible (build 8) | TH_3500 | - | 7e-74 | 40.62% (384) | PUTATIVE cytochrome P450 |
| M. thermoresistible (build 8) | TH_1956 | - | 5e-69 | 39.65% (401) | PROBABLE CYTOCHROME P450 125 CYP125 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2289 | cyp124 | 7e-66 | 39.22% (357) | cytochrome P450 124 CYP124 |
| M. gilvum PYR-GCK | Mflv_1321 | - | 1e-151 | 68.38% (389) | cytochrome P450 |
| M. tuberculosis H37Rv | Rv3518c | cyp142 | 4e-67 | 38.62% (391) | cytochrome P450 monooxygenase 142 |
| M. leprae Br4923 | MLBr_02088 | - | 6e-51 | 32.47% (388) | putative cytochrome p450 |
| M. abscessus ATCC 19977 | MAB_1406c | - | 4e-63 | 38.42% (367) | cytochrome P450 |
| M. marinum M | MMAR_4833 | cyp123B1 | 5e-71 | 38.40% (401) | cytochrome P450 123B1 Cyp123B1 |
| M. avium 104 | MAV_1339 | - | 1e-177 | 77.20% (386) | cytochrome P450 superfamily protein |
| M. smegmatis MC2 155 | MSMEG_3551 | - | 2e-68 | 37.10% (407) | linalool 8-monooxygenase |
| M. ulcerans Agy99 | MUL_4077 | cyp142A3 | 2e-65 | 38.10% (399) | cytochrome P450 142A3 Cyp142A3 |
| M. vanbaalenii PYR-1 | Mvan_5481 | - | 1e-148 | 67.10% (389) | cytochrome P450 |
CLUSTAL 2.0.9 multiple sequence alignment
TH_2649|M.thermoresistible__bu --------------------------------VLTTVPLHSPDFYAG-NP
MAV_1339|M.avium_104 -------------------------MQTHPPLRSPSFPLHSPDFYAG-NP
Mflv_1321|M.gilvum_PYR-GCK ----------------------------------MPPPLHSPAFYAG-DP
Mvan_5481|M.vanbaalenii_PYR-1 -------------------------------MSRLSNPLHSPAFYAG-DP
Mb2289|M.bovis_AF2122/97 -MGLNTAIATRVNGTPPPEVPIADIELGSLDFWALDDDVRDGAFATLRRE
MSMEG_3551|M.smegmatis_MC2_155 -MG----IAPRVNGAAPPDVPLSEINLGSWDFWALDDDIRDGAFATLRRE
Rv3518c|M.tuberculosis_H37Rv ---------------------------MTE---APDVDLADGNFYASREA
MUL_4077|M.ulcerans_Agy99 -------------------------MAMTKPLIKPDVDLTDGNFYASRQA
MAB_1406c|M.abscessus_ATCC_199 --------------------------MSVDVSHTVAPRYVPGTADNWTNP
MMAR_4833|M.marinum_M -------------------------MWQETLMSTVQLRYDPFDPEIQDDP
MLBr_02088|M.leprae_Br4923 MRTCVPTRTCVYAFIEYLSHNRPMGTNPPSLVEAQMLLLRLIDPGTRADP
TH_2649|M.thermoresistible__bu YPAYRELRATTPVVYNDV-----TNFWALLKYEDIRYVSSHPQLFSSTKG
MAV_1339|M.avium_104 YPAYRELRATAPVCWNDV-----TNFWALLKYEDIRFVSSNPALFTSTRG
Mflv_1321|M.gilvum_PYR-GCK FPAYRELRATDPVTWNEE-----HGFWALLKYEDIRYVSTNPALFSSARG
Mvan_5481|M.vanbaalenii_PYR-1 FPVYRELRATDPVCWNDE-----HEFWALLKYEDIRYVSTNPALFSSARG
Mb2289|M.bovis_AF2122/97 APISFWPTIELP-GFVAG-----NGHWALTKYDDVFYASRHPDIFSSYPN
MSMEG_3551|M.smegmatis_MC2_155 APISFHPAFDTEEGFPQG-----AGHWALTRHDDVFYASRHPELFSSASG
Rv3518c|M.tuberculosis_H37Rv RAAYRWMRANQP-VFRDR-----NGLAAASTYQAVIDAERQPELFSNAGG
MUL_4077|M.ulcerans_Agy99 REAYRWMRANQP-VFRDR-----NGLAAASTYQAVIDAERQPELFSNAGG
MAB_1406c|M.abscessus_ATCC_199 WPMYAALRDHDPVHHVVPEYTPDQDYYVLTRHADVYEAARDWETFSSARG
MMAR_4833|M.marinum_M YPVYRQLRDDAPVYHAT-----DTNTWVLSRHADVISALLDHHSYSSVDG
MLBr_02088|M.leprae_Br4923 FPVYRALIDYGPMQLPGMP------LTVFSSFSDCDEALRHPLSASDRLK
. . . . :.
TH_2649|M.thermoresistible__bu ITIPDPDQPEP-----VQEGNLIFTDPPRHRQLRKLINTAFTRRQVALLE
MAV_1339|M.avium_104 ITIPDPQLPNP-----VQQGSLIFTDPPRHRQLRKLINSGFTRRRVSVLE
Mflv_1321|M.gilvum_PYR-GCK ITVPDPAIENP-----VMEGSLIFTDPPRHRRLRKLINSGFTRRQVAILE
Mvan_5481|M.vanbaalenii_PYR-1 VTVPDPALENP-----VMEGSLIFTDPPRHRQLRKLINSGFTRRQVAILE
Mb2289|M.bovis_AF2122/97 ITINDQTPELA-----EYFGSMIVLDDPRHQRLRSIVSRAFTPKVVARIE
MSMEG_3551|M.smegmatis_MC2_155 IVIGDQTPELA-----EYFGSMIAMDDPRHTRLRNIVRSAFTPRVLAVIE
Rv3518c|M.tuberculosis_H37Rv IRPDQP-----------ALPMMIDMDDPAHLLRRKLVNAGFTRKRVKDKE
MUL_4077|M.ulcerans_Agy99 IRPDQD-----------ALPMMIDMDDPAHLWRRKLVNAGFTRKRVKDKE
MAB_1406c|M.abscessus_ATCC_199 LTVTYGDLEKTGM---GDNPPMVMQDPPTHTEFRKLVSRGFTPRQVTAVE
MMAR_4833|M.marinum_M VFPTP-PGSTFRE---SLLPMMILMDPPRHDQLRALVSKAFTPRRIAALT
MLBr_02088|M.leprae_Br4923 ATLAQQAIAAGAEPRPFYASSFMFLDPPDHTRLRKLVSKAFAPKVVQALE
:: * * * * :: .*: : :
TH_2649|M.thermoresistible__bu PKVREIVYGIFEGVAPGS---EQEFAESFAAPLPTRMIAELLGASPEDWE
MAV_1339|M.avium_104 PKIREIVRGILDGIERGA---VHEFAEQIAAPLPTRMIAELIGAPPDDWE
Mflv_1321|M.gilvum_PYR-GCK PKLRAFARTALDAIDPAG---GTEFAERIAAPLPTRMIAELLGAPDEDWE
Mvan_5481|M.vanbaalenii_PYR-1 PKLRAFARAALDAIDPS----ATEFAEQVAAPLPTRMIAELLGAPDEDWE
Mb2289|M.bovis_AF2122/97 AAVRDRAHRLVSSMIANNPDRQADLVSELAGPLPLQIICDMMGIPKADHQ
MSMEG_3551|M.smegmatis_MC2_155 DSVRDRARRLVAGMVDRNPDGHAELVTELAGPLPLQIICDMMGIPESDHQ
Rv3518c|M.tuberculosis_H37Rv ASIAALCDTLIDAVCER---GECDFVRDLAAPLPMAVIGDMLGVRPEQRD
MUL_4077|M.ulcerans_Agy99 HSIAQLCDTLIDAVCER---GECDFVRDLAAPLPMAVIGDMLGVLPEQRE
MAB_1406c|M.abscessus_ATCC_199 PKVREFVVQRLERLK-ERG--EGDIVVELFKPLPSMVVAHYLGVPEEDRT
MMAR_4833|M.marinum_M SAIEDLADHLTGGLIQEAG--SADFVADFAAVLPAMVIADLLGVPREDRT
MLBr_02088|M.leprae_Br4923 GDIAALVDSLLDKGAAAG---QFDVIADLAFPLAVAVICRLLGVPYEDAP
: :. . *. :: :* :
TH_2649|M.thermoresistible__bu RFRRWSDACTGTADPE--IEL-------DAMEAIGELYEYFQQLIAARR-
MAV_1339|M.avium_104 QFRAWSDAATGTADPE--IEL-------DPAVAAGQLYEYFQRLIAARR-
Mflv_1321|M.gilvum_PYR-GCK QFRRWSDAAVGMDDPD--VEL-------DTFTAMGELYQYFEKLIALRRN
Mvan_5481|M.vanbaalenii_PYR-1 QFRTWSDATVGMDDPD--VEL-------DTFAAMGELYQYFEAQIARRRD
Mb2289|M.bovis_AF2122/97 RIFHWTNVILGFGDPD--LAT----DFDEFMQVSADIGAYATALAEDRR-
MSMEG_3551|M.smegmatis_MC2_155 QIFHWTNVILGFGDPD--LTT----DFDEFVTVAMDIGAYATALADQRR-
Rv3518c|M.tuberculosis_H37Rv MFLRWSDDLVTFLSSH--VSQE---DFQITMDAFAAYNDFTRATIAARR-
MUL_4077|M.ulcerans_Agy99 MFLRWSDDLVTFLSSQ--VSQE---DFQVTIDAFAAYNDFTRATIAARR-
MAB_1406c|M.abscessus_ATCC_199 QFDAWTDGIVAAASGGAIDIEA---MQGEVAQTIGELMMYFTGLIERRR-
MMAR_4833|M.marinum_M QFRQWSNALVQSNP-----THG---ETGEALAAAAAIYGYFTDFLADRR-
MLBr_02088|M.leprae_Br4923 EFGRVSALLVQSVDPFITITGEPPEATEERLRAGVWLRDYLEQLVKCRR-
: : . : **
TH_2649|M.thermoresistible__bu --TEPRDDMMSVLAQAEV--DGARLSDEDLLNFAFLLLVAGNETTRNLIA
MAV_1339|M.avium_104 --ARPRADLLSVLAEAEI--DEHRLTDEDLLNFAFLLLVAGNETTRNLIA
Mflv_1321|M.gilvum_PYR-GCK GALRDSDDLLSVLVAAEV--DGVRLSDQDLLQFCLLLLVAGNETTRNLIA
Mvan_5481|M.vanbaalenii_PYR-1 GTLRDSDDLLSVLVAAEV--DGVRLTDQDLLQFCLLLLVAGNETTRNLVA
Mb2289|M.bovis_AF2122/97 --VNHHDDLTSSLVEAEV--DGERLSSREIASFFILLVVAGNETTRNAIT
MSMEG_3551|M.smegmatis_MC2_155 --SAPADDLTTSLVQAEV--DGERLTSAEVASFFILLVVAGNETTRNAIS
Rv3518c|M.tuberculosis_H37Rv --ADPTDDLVSVLVSSEV--DGERLSDDELVMETLLILIGGDETTRHTLS
MUL_4077|M.ulcerans_Agy99 --AEPTDDLVSVLVSSEV--DGERLSDDELVMETLLILIGGDETTRHTLS
MAB_1406c|M.abscessus_ATCC_199 --AEPEDDTVSHLVAAGVGADGDISGTLQILGFAFTMVTGGNDTTTGMLG
MMAR_4833|M.marinum_M --RQPRDDLMSALVCAEI--DGKHLSDDELLGFCLLLLIAGHETTSNLLA
MLBr_02088|M.leprae_Br4923 --GTPGEDLISRLIELDE--SGDQLTEEEIIATCGLLLVAGHETTVNLIA
* : * . :: :: .*.:** :
TH_2649|M.thermoresistible__bu LGTLALIEHPDQCRKLIENPT-LIPGAVEEMLRYTSPVTHMARQATEDVE
MAV_1339|M.avium_104 LGTLALIAHPDQYRLLVEEPA-RIPLAVEEMLRWNSPVVHMARTATADVE
Mflv_1321|M.gilvum_PYR-GCK LGTLALIEHPQQFRLLREHPE-LIPTAVEEFLRYTSPVANMTRCATRDVE
Mvan_5481|M.vanbaalenii_PYR-1 LGTLALIENPDQFRLLRQRRD-LVPTAVEEMLRYASPVANMTRCATRDVD
Mb2289|M.bovis_AF2122/97 HGVLALSRYPEQRDRWWSDFDGLAPTAVEEIVRWASPVVYMRRTLTQDIE
MSMEG_3551|M.smegmatis_MC2_155 HGVLALTRYPEQRRLWWSRFDELAPTAVEEIVRWASPVSYMRRTVTRDTE
Rv3518c|M.tuberculosis_H37Rv GGTEQLLRNRDQWDLLQRDPS-LLPGAIEEMLRWTAPVKNMCRVLTADTE
MUL_4077|M.ulcerans_Agy99 GGSEQLLRNRVQWDLLQSDRE-LLPGAIEEMLRWTAPVKNMCRMLTADTE
MAB_1406c|M.abscessus_ATCC_199 GAIQLLHQNPAQRQKLIDDPS-LIPGAVEEFLRLTSPVQGLARTATRDVI
MMAR_4833|M.marinum_M NAAVVLADYRDTRRQLAGDES-LLGAAVEELLRYDSPAQGLSRTLTRDVT
MLBr_02088|M.leprae_Br4923 NAVLAMLRNPSQWKALSSNPQ-RAPLVVEETLRYDPAIHLIGRVAAKDMT
. : .:** :* .. : * : *
TH_2649|M.thermoresistible__bu IRGRHIRKGDTVVMLYGSANRDEEIFGDDAEDFRIDRQPNPHIAFGCG-E
MAV_1339|M.avium_104 IRGQRIRAGEVVVMLYGSANRDEDVFGPDSEEFDVTRHPNPHIAFGCG-E
Mflv_1321|M.gilvum_PYR-GCK MRGRLIREGQYVTMLYGSANRDEDIFGPTSEQLDVTRNPNPHLAFGCG-E
Mvan_5481|M.vanbaalenii_PYR-1 IRGRSIRAGQYVTMLYGSANRDKDVFGPTSEQFDITRNPNPHLAFGCG-E
Mb2289|M.bovis_AF2122/97 LRGTKMAAGDKVSLWYCSANRDESKFAD-PWTFDLARNPNPHLGFGGGGA
MSMEG_3551|M.smegmatis_MC2_155 LAGTALPAGSKVTLWYGSANRDETKFDN-PWMFDVQRHPNPHVGFGGGGA
Rv3518c|M.tuberculosis_H37Rv FHGTALCAGEKMMLLFESANFDEAVFCE-PEKFDVQRNPNSHLAFGFG-T
MUL_4077|M.ulcerans_Agy99 FHGTALSKGEKIMLLFESANFDEAVFTD-PEKFDIQRNPNSHLAFGFG-T
MAB_1406c|M.abscessus_ATCC_199 IGDTTIPAGRRALLLYGSANRDEREYGNDAAELDVLRKPRNILTFSHG-N
MMAR_4833|M.marinum_M VHGVRMSAGESVLLLFGSANRDERVFA-DPDVFDIGRKPEHQVAFGRG-I
MLBr_02088|M.leprae_Br4923 IGQTTLTEGDTMVLLLAAANRDPAVYSR-PDEFDPDRPSSRHLAFAVG-S
. : * : :** * : . : * . : *. *
TH_2649|M.thermoresistible__bu HSCIGAQLARLEACVFFEVLLGRFPDLELVGTVDRMRA---TMVPGVKRM
MAV_1339|M.avium_104 HSCVGAQLARLEATVFFEELLRRYPRIELVGEVDRMRA---TMVPGVKRM
Mflv_1321|M.gilvum_PYR-GCK HSCLGAQLARLEARVLFEELLARFEHIEPAGEVLRMQA---TMVPGVRAM
Mvan_5481|M.vanbaalenii_PYR-1 HSCLGAQLARLEARVLFEELLNRFDHIELDGDVLRMQA---TMVPGVRQM
Mb2289|M.bovis_AF2122/97 HFCLGANLARREIRVAFDELRRQMPDVVATEEPARLLS---QFIHGIKTL
MSMEG_3551|M.smegmatis_MC2_155 HFCLGANLARREITVLFSELHRHLPDIVATEEPDRLQS---AFIHGIKRL
Rv3518c|M.tuberculosis_H37Rv HFCLGNQLARLELSLMTERVLRRLPDLRLVADDSVLPLRPANFVSGLESM
MUL_4077|M.ulcerans_Agy99 HFCMGNQLARLELSLMTARVVQRLPDLRLADQDSRLPLRPANFVSGLESM
MAB_1406c|M.abscessus_ATCC_199 HHCLGAAAARMQSRIALEELLTRIPDFEVDLDGVTWAD--GSYVRRPLTV
MMAR_4833|M.marinum_M HFCLGASLARMEARIALRALLARVPNWEVDLERAQRLR--SGPIRGYLSL
MLBr_02088|M.leprae_Br4923 HFCLGAALARLEATVTLSAISARFPQVQLAGELVYKPN---VAMRGMSAL
* *:* ** : : : : : :
TH_2649|M.thermoresistible__bu PVRLGAGR-------------
MAV_1339|M.avium_104 PVRMGA---------------
Mflv_1321|M.gilvum_PYR-GCK PVRLRAATDPRRAKARAG---
Mvan_5481|M.vanbaalenii_PYR-1 PVRLSATAAEPRETGTAAVSV
Mb2289|M.bovis_AF2122/97 PVTWS----------------
MSMEG_3551|M.smegmatis_MC2_155 PVAWR----------------
Rv3518c|M.tuberculosis_H37Rv PVVFTPSPPLG----------
MUL_4077|M.ulcerans_Agy99 PVVFTPSRPLR----------
MAB_1406c|M.abscessus_ATCC_199 PIRVR----------------
MMAR_4833|M.marinum_M PISWSAN--------------
MLBr_02088|M.leprae_Br4923 PVQV-----------------
*: