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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4029 | - | - | 100% (528) | putative PE-PPE, C-terminal domain protein |
| M. thermoresistible (build 8) | TH_3724 | - | 1e-33 | 37.50% (288) | PUTATIVE putative PE-PPE, C-terminal domain protein |
| M. thermoresistible (build 8) | TH_4255 | - | 9e-11 | 23.69% (363) | PUTATIVE putative PE-PPE, C-terminal domain protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1465 | PE16 | 5e-33 | 33.07% (384) | PE family protein |
| M. gilvum PYR-GCK | Mflv_1918 | - | 1e-72 | 44.53% (384) | hypothetical protein Mflv_1918 |
| M. tuberculosis H37Rv | Rv1430 | PE16 | 5e-33 | 33.07% (384) | PE family protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4141 | - | 1e-20 | 28.76% (386) | PE/PPE family protein |
| M. marinum M | MMAR_4321 | - | 2e-32 | 30.95% (391) | PE family protein |
| M. avium 104 | MAV_1760 | - | 4e-05 | 24.65% (215) | hypothetical protein MAV_1760 |
| M. smegmatis MC2 155 | MSMEG_5455 | - | 8e-72 | 35.98% (503) | PE family protein |
| M. ulcerans Agy99 | MUL_0967 | - | 6e-32 | 29.82% (389) | PE family protein |
| M. vanbaalenii PYR-1 | Mvan_4815 | - | 1e-74 | 38.00% (529) | hypothetical protein Mvan_4815 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1465|M.bovis_AF2122/97 -----MSFVFAVPEMVAATASDLASLGAALSEATAAAAIPTTQVLAAAAD
Rv1430|M.tuberculosis_H37Rv -----MSFVFAVPEMVAATASDLASLGAALSEATAAAAIPTTQVLAAAAD
MMAR_4321|M.marinum_M -----MIDLLASPQAMTATATEVAEIGLAINQADLAVAGPTTGLAAAAAD
MUL_0967|M.ulcerans_Agy99 ---MAVIDLLASPQAMTATATEVAEIGLAINQADLAVAGPTTGLAAAAAA
TH_4029|M.thermoresistible__bu ------------------------------------------------VR
MSMEG_5455|M.smegmatis_MC2_155 --------------------------------------------MGRLLH
Mflv_1918|M.gilvum_PYR-GCK MGKGDFGLKASEFTGRSSTRFADSVRRRPGGATYGLYRHDGLGVGTWAWV
Mvan_4815|M.vanbaalenii_PYR-1 ----------------------MRLIIRPLAALF---------------L
MAB_4141|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1760|M.avium_104 -----------------------------------------------MKQ
Mb1465|M.bovis_AF2122/97 EVSAAIAELFGAHGQEFQALSAQASAFHDRFVRALSAAAGWYVDAEAANA
Rv1430|M.tuberculosis_H37Rv EVSAAIAELFGAHGQEFQALSAQASAFHDRFVRALSAAAGWYVDAEAANA
MMAR_4321|M.marinum_M EVSEAIATLFDNYAQGYQAVSRQAAAFHDAFAQTLFAASDSYVRAEAAAV
MUL_0967|M.ulcerans_Agy99 EVSEAIATLFDNYAQGYQAVSRQTAAFHDAFAQTLFAASDSYVRAEAAAV
TH_4029|M.thermoresistible__bu SAVLVGCVLTTVLALAWVSPMPAMVQVLAKT--MLVIGGTGHPLVDPSGP
MSMEG_5455|M.smegmatis_MC2_155 SLSTAFLVFVAVVVLCVSTSMPTAAHLLLNHPHALVIGGTGTPVPPPE--
Mflv_1918|M.gilvum_PYR-GCK FARSSRSFPRSRRCWRYPRGVPTPVAVLVANTTALVMGGTFHPLTGPRDS
Mvan_4815|M.vanbaalenii_PYR-1 VLASVAALPLS---WTLSG----VVVALTSNTTALIMGGSFHPLAEPADA
MAB_4141|M.abscessus_ATCC_1997 -MAGQYSVPGKRHSLRRYVATITAVAATCTVLAPLAMESRTIASTLAS--
MAV_1760|M.avium_104 LLAGVTALLSVSTAGYFGIGTAAADGGPIGGPPTPGAPGDQTAYALGG--
.
Mb1465|M.bovis_AF2122/97 ALVD------------------TAATGASELGSGG-----RTALILGSTG
Rv1430|M.tuberculosis_H37Rv ALVD------------------TAATGASELGSGG-----RTALILGSTG
MMAR_4321|M.marinum_M KALAGLTEPVANLFAPVLSGPESVAASATALLSGAPLKPVEAALILSESG
MUL_0967|M.ulcerans_Agy99 KALAGLTEPVANLFAPVLSGPESVAASATALLSGAPLKPVEAALILSESG
TH_4029|M.thermoresistible__bu GRPVDGWPYPSRPLGEPGMATEGDGAPAGYVLLVH-----DNFVVPGGTD
MSMEG_5455|M.smegmatis_MC2_155 -----------------------------YVNGQT-----DNYIGAEFPG
Mflv_1918|M.gilvum_PYR-GCK ---------------------------PEFVTAYL-----DNAVDNQISA
Mvan_4815|M.vanbaalenii_PYR-1 ---------------------------PPFVTAYL-----DNAVTGHLDP
MAB_4141|M.abscessus_ATCC_1997 -----------------------------YVIGIG-----GNNDGASANI
MAV_1760|M.avium_104 ----------------------------AHVLGIPYDQYIRMEGADWFPG
:
Mb1465|M.bovis_AF2122/97 TPRPPFDYMQQVYDRYIAPHYLG---YAFSGLYTPAQFQPWTGIPSLTYD
Rv1430|M.tuberculosis_H37Rv TPRPPFDYMQQVYDRYIAPHYLG---YAFSGLYTPAQFQPWTGIPSLTYD
MMAR_4321|M.marinum_M VPTPSASYISDVYTKYVEPNFPSA--TAPQGVSTPNGLYPFTGIKDLTLD
MUL_0967|M.ulcerans_Agy99 VPTPSASYISDVYTKYVEPNFPSA--TAPQGVSTPNGLYPFTGIKDLSLD
TH_4029|M.thermoresistible__bu GHRYR------AVAVYTPQEFFPV--AGSRTFNDSVTDGFANTVNCAHSS
MSMEG_5455|M.smegmatis_MC2_155 EYRY---------AVHTPQNFWPV--YGSMSFDESTVAGLA-ALQAEMAK
Mflv_1918|M.gilvum_PYR-GCK AYGYA---VTNAVAVYTPEEFFPL--G-GLTFDDSVAEGLANLGRCLRAE
Mvan_4815|M.vanbaalenii_PYR-1 AFADASGPVTNAVAVYTPEQFFPI--G-QLTFARSVAEGLVNLHRCLGAE
MAB_4141|M.abscessus_ATCC_1997 PRKLGGAYSVDYHPVSYPGAIWPVSGLTAPTFKTSVAQGRTNLNDEIVTA
MAV_1760|M.avium_104 QQRQIVRYPAGQVQGHVLERLFPGIGKLDESFPGLGMDGPSVGESVAEGI
.
Mb1465|M.bovis_AF2122/97 QSVAEGAGYLHTAIMQQVA---AGNDVVVLGFSQGASVATLEMRHLASLP
Rv1430|M.tuberculosis_H37Rv QSVAEGAGYLHTAIMQQVA---AGNDVVVLGFSQGASVATLEMRHLASLP
MMAR_4321|M.marinum_M ISLARGATILNDAILQQLAALPAGSSVAVLGYSQSAVLSSLVMPKL--LA
MUL_0967|M.ulcerans_Agy99 ISLARGATILNDAILQQLAALPAGSSVAVLGYSQSAVLSSRVMPKL--LA
TH_4029|M.thermoresistible__bu AGCIAHIYPDTDVGLTDPVADDDGSGVVVVGYSQSAVIASLVKQHL---L
MSMEG_5455|M.smegmatis_MC2_155 EG-------------------HFGSPLVILGYSSSTRILTADKNRR---I
Mflv_1918|M.gilvum_PYR-GCK PGCVFNADPAVAARV-GTVAPRHDDTFVVFGYSQSAAVASLLKRQL---I
Mvan_4815|M.vanbaalenii_PYR-1 TDCVFNDDPAIRP---HAVAPRAGDAMMAFGYSQSAVIASLAKLDL---I
MAB_4141|M.abscessus_ATCC_1997 GN----------------------QPITIVGYSLGAVVVSKSHSDL---L
MAV_1760|M.avium_104 DN-------------LDAAIRTTGRPGTAIGLSEGAFVVDGEQARLAN--
. .* * .: :
Mb1465|M.bovis_AF2122/97 AGVAPSPDQLSFVLLGNPN--NPNGGILARFP-GLYLQSLGLTFNGATPD
Rv1430|M.tuberculosis_H37Rv AGVAPSPDQLSFVLLGNPN--NPNGGILARFP-GLYLQSLGLTFNGATPD
MMAR_4321|M.marinum_M EGVTSS--QVNFVLLGNPM--NPNGGVLARFP-DLTLPSLGFTFYGATPD
MUL_0967|M.ulcerans_Agy99 EGVTSS--QVNFVLLGNPM--NPNGGVLARFP-DLTLPSLGFTFYGATPD
TH_4029|M.thermoresistible__bu DNPDR-APGTSFVLLGNPM--RPNGGLLQRLPRGMTIPILDVTAFGPTPT
MSMEG_5455|M.smegmatis_MC2_155 ADGDY-AVDINYVLVSDVA--KGNGGVMARFP-GWHIPILGVTFDGATRT
Mflv_1918|M.gilvum_PYR-GCK DAPGPEPAATTFMLAANPM--RPNGGVLGRFP-ALTIPILGITFHGATPT
Mvan_4815|M.vanbaalenii_PYR-1 QRYQPGDPSVSFMLVANPM--RPNGGILMRLHGWPTIPILEIPFPGASPT
MAB_4141|M.abscessus_ATCC_1997 QRYPGGNPNIQFVLMGSAN--TPNGGIFARFP-WLKIPLADIESNGAWEP
MAV_1760|M.avium_104 DPTAPPPNTLNFATFGDPIGRHAFGQSFLTAMFGVGSVVPALDYTMPPPY
: .. * : . .
Mb1465|M.bovis_AF2122/97 TD---------YATTIYTTQYDGFA-DFPKYPLNILADVNALLGIYYSHS
Rv1430|M.tuberculosis_H37Rv TD---------YATTIYTTQYDGFA-DFPKYPLNILADVNALLGIYYSHS
MMAR_4321|M.marinum_M NA---------FPTVSYTLEYDGFA-DFPRYPINLLADINAVMGIPFVHA
MUL_0967|M.ulcerans_Agy99 NA---------FPTVSYTLEYDGFA-DFPRYPINLLADINAVMGIPFVHA
TH_4029|M.thermoresistible__bu NSCDEQGENCAHPTLDVAVQHDALGGDFPIYPLHLPAVANSLLSYALLHG
MSMEG_5455|M.smegmatis_MC2_155 DS-----DGYAFDTKSISFVHDGWS-DFPVYPLNVLALANAVAGIAVLHP
Mflv_1918|M.gilvum_PYR-GCK AG---VDG--AYRTVDVVRQYDGLGGDFPVRPLNLLATVNALLGYGIMHG
Mvan_4815|M.vanbaalenii_PYR-1 DSAVLPDGRHVYPTVDVARQYDGLGGDFPVRPLNLVATVNALLGYALLHG
MAB_4141|M.abscessus_ATCC_1997 DQ---------FKTKVINTEYDTYG-DFPAY-FNPLALANSIAAIQYAHP
MAV_1760|M.avium_104 ES--------QYDTNRFVAAYDSIA-DFPDRPDNMFALANTLMGLATGHT
. * :* . *** : * *:: . *
Mb1465|M.bovis_AF2122/97 LYYGLTPEQVASG---IVLPVSSPDTNTTYILLPNEDLPLLQPLRGI---
Rv1430|M.tuberculosis_H37Rv LYYGLTPEQVASG---IVLPVSSPDTNTTYILLPNEDLPLLQPLRGI---
MMAR_4321|M.marinum_M DYQHLTQAQLDSA---VQLPTEGP-TQSTYYMIPTEHLPLLAPLRFIPY-
MUL_0967|M.ulcerans_Agy99 DYQDLTQAQLDSA---VQLPTEGP-TQSTYYMIPTEHLPLLAPLRFIPY-
TH_4029|M.thermoresistible__bu TMPEQHLDDAV---------PQGVHGDTTYYLLPTDLVPLLMPFEGV---
MSMEG_5455|M.smegmatis_MC2_155 TYPELDRPDLV---------PVGSTGDTEYFVIGTDIMPLLMPLETIG--
Mflv_1918|M.gilvum_PYR-GCK ETVDVPFAQAR---------FQGREGDTDYYLIGTDLLPLLQPLLLF---
Mvan_4815|M.vanbaalenii_PYR-1 SAVDIPLAQAR---------FQGRQGDTGYYLVETDLVPLLQPFAFF---
MAB_4141|M.abscessus_ATCC_1997 DAYYDRIDPAALDDPDNPNVVKTVQGNTTYYLVRAEHLPLLQPLRDLTNP
MAV_1760|M.avium_104 AVAFTNPSMVPPQ--NIRTTINSRGAKDTTIMIPEKHLPLVMPLKYIG--
. :: . :**: *: .
Mb1465|M.bovis_AF2122/97 -VPEPLLDLIEPDLRAIIELGYDR------TGYADVPTPAALFPVHIDPI
Rv1430|M.tuberculosis_H37Rv -VPEPLLDLIEPDLRAIIELGYDR------TGYADVPTPAALFPVHIDPI
MMAR_4321|M.marinum_M -VGDPLAELLEPNLRVLVNLGYGDPAYGYDTGPANVPTPFGLFPP-VSPL
MUL_0967|M.ulcerans_Agy99 -VGDPLAELLEPNLRVLVNFGYGDPAYGYDTGPANVPTPFGLFPP-VSPL
TH_4029|M.thermoresistible__bu -VPRPILVALDEPLRVLIEGGYRR------DISPGEPTPAYLIPV-INPV
MSMEG_5455|M.smegmatis_MC2_155 -VPRPILLAVDEPLRVLVEAGYRR------DIAPGAPTPARLIPI-VNPI
Mflv_1918|M.gilvum_PYR-GCK -VPRPILSALDAPLRVLVEDAYDR------DAGPGDPTTARWWPV-KDFA
Mvan_4815|M.vanbaalenii_PYR-1 -VPRPILKAIDAPLRVVIEDAYDR------DVGPGVATRASWRPI-KDIV
MAB_4141|M.abscessus_ATCC_1997 IGASFVLDAIEPTLRVFIDMAYDR------DTGPGTTTQFSFFTPSKNIV
MAV_1760|M.avium_104 -IDENTLNKLDAILTPRVNAGYSR------------NDDPATAPVQVDPV
:: * :: .* . .
Mb1465|M.bovis_AF2122/97 AVPPQIGAAIGGPLTALDGLL--DTVINDQLNP-VVTSGIYQAGAELSVA
Rv1430|M.tuberculosis_H37Rv AVPPQIGAAIGGPLTALDGLL--DTVINDQLNP-VVTSGIYQAGAELSVA
MMAR_4321|M.marinum_M TVAEHLAAGTQQGIVNSG------AALQAQGPPSIPLSDIAHTLTANPPW
MUL_0967|M.ulcerans_Agy99 TVAEHLAAGTQQGIVNSG------AALQAQGPPSIPLSDIAHTLTANPPW
TH_4029|M.thermoresistible__bu SLTVNLIRSVPVGLDNGIEELTGERPLGTTDPGPYGVGGDDADLRGLPAG
MSMEG_5455|M.smegmatis_MC2_155 TLTRNFIAAIPVGVDDAMEELGHGRPLGTQPSGVFGVGGEDTELKGLPAG
Mflv_1918|M.gilvum_PYR-GCK GTAAKLIASVPVAVDNLTEGFGLGRVLGTPVPGVFGVGGPDLPDVDEGGA
Mvan_4815|M.vanbaalenii_PYR-1 GLAARLVASIPVAVDNLTEGLGLGRVLGTTEPGAFGVGGPDLPAEPEP-A
MAB_4141|M.abscessus_ATCC_1997 DAFNKLPTAIAEGAHNVENGLAGATPKQSASPEKPASPPVPQPGPTNPGS
MAV_1760|M.avium_104 HGFDPAEVTAPANQATFGGG---ADPLSQIMAGAMSVLSHGAGEADH---
Mb1465|M.bovis_AF2122/97 AAGY----------------GAPAGVTNAIFIGQQVLPILVEGPGALVTA
Rv1430|M.tuberculosis_H37Rv AAGY----------------GAPAGVTNAIFIGQQVLPILVEGPGALVTA
MMAR_4321|M.marinum_M AGTP----------------ALPPSTSPASSIEDFILAVQAAN-SSISRG
MUL_0967|M.ulcerans_Agy99 AGTP----------------ALPPSTSPASSIEDFILAVQAAN-SSISRG
TH_4029|M.thermoresistible__bu LVPLGST------------SPTPILPETAAPAAEKPAMRVDSGTPKPIIR
MSMEG_5455|M.smegmatis_MC2_155 VISL----------------AKPTLPVSSHTTVVEKTERKDLAKPAAEPE
Mflv_1918|M.gilvum_PYR-GCK VTSD---------------IDEDAVAQRDSASSTERSAPAEESRSAVGGA
Mvan_4815|M.vanbaalenii_PYR-1 VPDE---------------SVEPAVPEQDPESVEYDGGRAAGEGSAGEGS
MAB_4141|M.abscessus_ATCC_1997 ATTQIPAPEAPTPSVVSLSTAEPPAPPASAKAADPTAISVSTAGASTARD
MAV_1760|M.avium_104 --------------------------------------------------
Mb1465|M.bovis_AF2122/97 DTHYLVDAIQDLAAGDLSGFNQNLQLIPATNIALLVFAAGIPAVAAVAIL
Rv1430|M.tuberculosis_H37Rv DTHYLVDAIQDLAAGDLSGFNQNLQLIPATNIALLVFAAGIPAVAAVAIL
MMAR_4321|M.marinum_M FVKTLSTAYATLLP--TTDIASELVFTLPSYNLNLFLDGVIQAINGQPIE
MUL_0967|M.ulcerans_Agy99 FVKTLSTAYATLLP--TTDIASELVFTLPSYNLNLFLDGVIQAINGQPIG
TH_4029|M.thermoresistible__bu TAAPSAPLLRTPRPPAGERLGERLGERLNQRRGPILDASRLLRPGRAAAG
MSMEG_5455|M.smegmatis_MC2_155 PVVEDEPAVEDETPVADTKKASPKPLRPKVRGPISFDAPKLPTIRKATGD
Mflv_1918|M.gilvum_PYR-GCK DSDGRDDVVDPEPAAPEAETS---------EAETVTET------EADDAD
Mvan_4815|M.vanbaalenii_PYR-1 AGAESVDRVEPDAAPVESDPAPVEADPAPVEADPAPEKSDPAPVEADPAP
MAB_4141|M.abscessus_ATCC_1997 QDFQPDTKPDPKSTPPPTKDSVGEADKSKNTLKPTLRLPKLPVAQPGTAP
MAV_1760|M.avium_104 --------------------------------------------------
Mb1465|M.bovis_AF2122/97 TGQDFPV-------------------------------------------
Rv1430|M.tuberculosis_H37Rv TGQDFPV-------------------------------------------
MMAR_4321|M.marinum_M GLINAIGNPIAASTGLITLAGGFQLIVISYALDTILFGTPHPLP------
MUL_0967|M.ulcerans_Agy99 D-------------------------------------------------
TH_4029|M.thermoresistible__bu R------GVTDTGRPGPV---DAAPNP-ESDTKSQEQP------------
MSMEG_5455|M.smegmatis_MC2_155 RPLKRLLSALTPKRPKPASSHDAGPAAGNKDTDNADKPAARADDAA----
Mflv_1918|M.gilvum_PYR-GCK D--------ADDGADADDEDIDADGADADGEDTAG------NTAEAA---
Mvan_4815|M.vanbaalenii_PYR-1 EK-------SDPGSDASADDGEAGAATTPTETDEADEPPDEDTAEAA---
MAB_4141|M.abscessus_ATCC_1997 KSPKFPSLKNHLKSVPGLSEKKNPAADASSKHSQPANAPAHTSDKTSDHA
MAV_1760|M.avium_104 --------------------------------------------------
Mb1465|M.bovis_AF2122/97 --------
Rv1430|M.tuberculosis_H37Rv --------
MMAR_4321|M.marinum_M --------
MUL_0967|M.ulcerans_Agy99 --------
TH_4029|M.thermoresistible__bu --------
MSMEG_5455|M.smegmatis_MC2_155 --------
Mflv_1918|M.gilvum_PYR-GCK --------
Mvan_4815|M.vanbaalenii_PYR-1 --------
MAB_4141|M.abscessus_ATCC_1997 SETGRGAA
MAV_1760|M.avium_104 --------