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M. thermoresistible (build 8) TH_3989 (-)

annotation: acyl-CoA dehydrogenase domain protein
coordinates: 262607 - 263764
length: 386

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3989--100% (386)acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)TH_4559-e-10955.53% (371) PUTATIVE putative acyl-CoA dehydrogenase
M. thermoresistible (build 8)TH_2026-e-10353.24% (370) transposase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3592fadE313e-4536.53% (375) acyl-CoA dehydrogenase FADE31
M. gilvum PYR-GCKMflv_5166-1e-12562.63% (372) Fis family transcriptional regulator
M. tuberculosis H37RvRv3562fadE313e-4536.53% (375) acyl-CoA dehydrogenase FADE31
M. leprae Br4923MLBr_00737fadE252e-1526.14% (241) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977MAB_0597-1e-4333.58% (399) acyl-CoA dehydrogenase FadE
M. marinum MMMAR_3511-1e-12361.46% (371) acyl-CoA dehydrogenase
M. avium 104MAV_2554-1e-10956.76% (370) acyl-CoA dehydrogenase, central region
M. smegmatis MC2 155MSMEG_2879-1e-12961.79% (390) acyl-CoA dehydrogenase
M. ulcerans Agy99MUL_2757-1e-12360.85% (378) acyl-CoA dehydrogenase
M. vanbaalenii PYR-1Mvan_3917-1e-13163.49% (378) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb3592|M.bovis_AF2122/97            --------------MDLNFDDETLAFQAEVREFLAANAA------SIPTK
Rv3562|M.tuberculosis_H37Rv         --------------MDLNFDDETLAFQAEVREFLAANAA------SIPTK
MMAR_3511|M.marinum_M               MADALMALPRLVPPAGALDSPRADVLRGEVRAFLAEQSA------AGGFT
MUL_2757|M.ulcerans_Agy99           -----MALPRLVPPAGALDSPRADVLRGEVRAFLAEQSA------AGGFT
MSMEG_2879|M.smegmatis_MC2_155      -----MAIPRLVP-ALDTEPADATALRAEVRAFLDEQRA------AGTFT
Mvan_3917|M.vanbaalenii_PYR-1       -----MAAARLVP-PCTAETSEAHELRAEVRRFLAEQLA------AGAFT
Mflv_5166|M.gilvum_PYR-GCK          -----MNTSRLVP-PVADDPHAMDGLRDEVRQFVAEQRD------AGRIG
TH_3989|M.thermoresistible__bu      -----MTAVERLP--ASAPVEVAPELRAEVREFLDEERA------AGRFT
MAV_2554|M.avium_104                -------MVNSFD-ALSAREPELVKLRHAVRDFLESDRA------EFGWQ
MAB_0597|M.abscessus_ATCC_1997      ---MVESQVSPAPAGEPMSEMSDDQVRTEIREWLAENLVGEFAELKGLGG
MLBr_00737|M.leprae_Br4923          ----MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAP---------H
                                                             .:  :*     :             

Mb3592|M.bovis_AF2122/97            SYDNAEGFAQHRYWDRVLFDAGLSVITWPAKYGGRDAPLLHWIVFEEEYF
Rv3562|M.tuberculosis_H37Rv         SYDNAEGFAQHRYWDRVLFDAGLSVITWPAKYGGRDAPLLHWIVFEEEYF
MMAR_3511|M.marinum_M               PSVDAWLSAWDEDFTAALADRGWLGMTVPVEYGGHGRTFLERFVVTEELL
MUL_2757|M.ulcerans_Agy99           PSVDAWLSAWDEDFTAALADRGWLGMTVPVEYGGHGRTFLERFVVTEELL
MSMEG_2879|M.smegmatis_MC2_155      PAVDAWLCGWDEKFTTALAARGWLGMTVPKEYGGQGRSFLHRFVVTEELL
Mvan_3917|M.vanbaalenii_PYR-1       PTADAWLCGWDEDFTAALAERGWLGMTVPVAYGGHGRSFLERFVVTEELL
Mflv_5166|M.gilvum_PYR-GCK          RQVDSWLTGWDEDFSRALAARGWLGMTVPEEYGGHGRSFLERFVVTEELL
TH_3989|M.thermoresistible__bu      PRCDAWLVGWDPEFSRRLAGRGWLGMTLPARYGGHERSTLERYVVTEELL
MAV_2554|M.avium_104                PGVDSWLAGWDEEFSGRLGAAGFTGLTIPQRYGGHGLGHLHRYVVTEELI
MAB_0597|M.abscessus_ATCC_1997      PGSEHEAFEERLAWNRHLAAAGWTCLGWPVEHGGRGATVSQRVIFYEEYA
MLBr_00737|M.leprae_Br4923          AADVDQRARFPEEALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVA
                                                     *   *   :  *  :**:        :. **  

Mb3592|M.bovis_AF2122/97            RAGAPGRASANGTSMLAPTLFAHGTAEQLDRILPKMASGEQIWAQAWSEP
Rv3562|M.tuberculosis_H37Rv         RAGAPGRASANGTSMLAPTLFAHGTAEQLDRILPKMASGEQIWAQAWSEP
MMAR_3511|M.marinum_M               AAGAPVAAHWIADRQIVPSLLKYGTELQKSHFLPRIVRGECFFGIGMSEP
MUL_2757|M.ulcerans_Agy99           AVGAPVAAHWIADRQIVPSLLKYGTELQKSHFLPRIVRGECFFGIGMSEP
MSMEG_2879|M.smegmatis_MC2_155      AAGVPVAAHWIADRQIVPSLLKYGTERQKQEFLPRIAAGQCFFGIGMSEP
Mvan_3917|M.vanbaalenii_PYR-1       AAGAPVAAHWIADRQIVPSLLKYGTEFQKTEFLPKIAGGTCFFGIGMSEP
Mflv_5166|M.gilvum_PYR-GCK          AAGAPVGAHWIADRQIVPSLLKYGTETQKRRYLPEIAAGRCYFGIGMSEP
TH_3989|M.thermoresistible__bu      AAGAPVAAHWIADRQIGPSLLRYGTEAQRNRFLPAIARGECFFGIGMSEP
MAV_2554|M.avium_104                AAGAPVAAHWTADRQVAPALLTYGNEEQRERLLPKIVAGQLFSSIGMSEH
MAB_0597|M.abscessus_ATCC_1997      RAEAPHKVNHLGEELLGPTLIAYGTPEQQQRFLPAIRDVTELWCQGYSEP
MLBr_00737|M.leprae_Br4923          RVDASASLIPAVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSER
                                     . ..              *:  *.     . ** :         . ** 

Mb3592|M.bovis_AF2122/97            ESGSDLASLRSTASKVDGGWLLNGQKIWSSRAPFADMGFGLFRS---DPA
Rv3562|M.tuberculosis_H37Rv         ESGSDLASLRSTASKVDGGWLLNGQKIWSSRAPFADMGFGLFRS---DPA
MMAR_3511|M.marinum_M               DSGSDLASVRTRAVRGEGGWLLSGTKVWTSGAHRAHAFIVLARTAPVDP-
MUL_2757|M.ulcerans_Agy99           DSGSDLASVRTRAVRGEGGWLLSGTKVWTSGAHRAHAFIVLARTAPVDP-
MSMEG_2879|M.smegmatis_MC2_155      DSGSDLASVRTRAVQVEGGWRLTGTKVWTSGAHRAHAFIVLARTAPVDP-
Mvan_3917|M.vanbaalenii_PYR-1       DSGSDLASVRTRAERVDGGWRLTGTKVWTSGAHLAHAFIALARTAPVDP-
Mflv_5166|M.gilvum_PYR-GCK          DSGSDLASVRTKASPVDGGWSVTGAKVWTSGAHRADAFICLARTEPVDP-
TH_3989|M.thermoresistible__bu      DSGSDLASVRTKATRVDGGWRIDGTKIWTSGAHRAHAFFVLARSTPLAES
MAV_2554|M.avium_104                GAGSDLAAVQTKAVRADGGWLLSGSKVWTSGAHHAHQVVVLARTSPPDP-
MAB_0597|M.abscessus_ATCC_1997      GAGSDLANVSTSAVLDGGDWVINGQKVWTSLALQSQWCFVVARTEPGSS-
MLBr_00737|M.leprae_Br4923          EAGSDAASMRTRAKADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDKG-
                                     :*** * : : *    ..* : * * * : .  :     :  :      

Mb3592|M.bovis_AF2122/97            VERHRGLTYFMFDLKAKGVTVRPIAQLGGDTG--FGEIFLDDVFVPDRDV
Rv3562|M.tuberculosis_H37Rv         VERHRGLTYFMFDLKAKGVTVRPIAQLGGDTG--FGEIFLDDVFVPDRDV
MMAR_3511|M.marinum_M               DHRHAGLSQFIVDLRGPGVQTRPIISMNGAHH--FNEVILDNACVPDEMV
MUL_2757|M.ulcerans_Agy99           DHRHAGLSQFIVDLRGPGVQTRPIISMNGAHH--FNEVILDNAHVPDEMV
MSMEG_2879|M.smegmatis_MC2_155      AHRHAGLSQFIVRFDGPGVEVRPIISMNGGHH--FNEVILDDAFVPDDMV
Mvan_3917|M.vanbaalenii_PYR-1       AHRHAGLSQFIVDLRGPGVEIRPIVSMNGAHH--FNEVLLDGAFVPDEMV
Mflv_5166|M.gilvum_PYR-GCK          AHRHAGLSQFIVDLRSPGVDIRPIVSMDGRHH--FNEVLLDDVFVADDMV
TH_3989|M.thermoresistible__bu      PSRHAGLSQFIVLLDSPGVEIRPIPLLTGEHH--FNEVHLDGVFVPDDMV
MAV_2554|M.avium_104                EHRHAGFSQFLVPCDAEGVRIEPIILMSGAHH--FNEVLFEQVFVPDADV
MAB_0597|M.abscessus_ATCC_1997      --RHKGLSYLLVPLDQPGVEIRPIIQLTGTSE--FNEVFFDNARTSADLV
MLBr_00737|M.leprae_Br4923          ---ANGISAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRI
                                         *:: ::.     *.   *     *       *: ::    .   :

Mb3592|M.bovis_AF2122/97            IGAPNDGWRAAMSTSSNERGMS--------LRSPARFLASAERLVQLWKD
Rv3562|M.tuberculosis_H37Rv         IGAPNDGWRAAMSTSSNERGMS--------LRSPARFLASAERLVQLWKD
MMAR_3511|M.marinum_M               FGAIGNGWTQVTSELSFERSGP--------ERFLSTFVLLAATAESMAEQ
MUL_2757|M.ulcerans_Agy99           FGAIGNGWTQVTSELSFERSGP--------ERFLSTFVLLAATAESMAEQ
MSMEG_2879|M.smegmatis_MC2_155      FGQIGNGWQQVTSELSFERSGP--------ERLLSTFVLLAQTTDSMARQ
Mvan_3917|M.vanbaalenii_PYR-1       FGSIGAGWEQVTSELAFERSGP--------ERFLSTFVLLDACAETIASQ
Mflv_5166|M.gilvum_PYR-GCK          FGAIGDGWQQVTSELAFERSGP--------ERFLSTFPLLAELAALMNDG
TH_3989|M.thermoresistible__bu      LGEIGEGWRQVTSELAFERSGP--------ERFLSTFPLLTTLVDELARR
MAV_2554|M.avium_104                LGEVGNGWHQVTSELSFERSGP--------ERILSTGPLLFAAIRTLGRG
MAB_0597|M.abscessus_ATCC_1997      VGEPGDGWRVAMGTLTFERG----------VSTLGNQITYARELSRLAEL
MLBr_00737|M.leprae_Br4923          IGEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGES
                                    .*  . *:  . .     *                           :   

Mb3592|M.bovis_AF2122/97            RGSPPEFADRVADAWIKAQAYRLQTFGTVTRLAAGGE-LGAESSVTKVFW
Rv3562|M.tuberculosis_H37Rv         RGSPPEFADRVADAWIKAQAYRLQTFGTVTRLAAGGE-LGAESSVTKVFW
MMAR_3511|M.marinum_M               RFTRDQ---QLGRLVARIAGLHQMSAAVAGALERNDP-ADLPAAVVKVLG
MUL_2757|M.ulcerans_Agy99           RFTRDQ---QLGRLVARIAGLHQMSAAVAGALERNDP-ADLPAAVVKVLG
MSMEG_2879|M.smegmatis_MC2_155      QISRDA---DLGRLVARIAGLHHMSMAVAGALERHEP-ADVPAAVVKVLG
Mvan_3917|M.vanbaalenii_PYR-1       RVPRSD---DLGRLVARVAGLHQMSSAVAGALQRHEP-ADVPAAVVKVLG
Mflv_5166|M.gilvum_PYR-GCK          -LPRHN---DLGRYVARVAGLHQMSTAVAGALERHEP-ADTAAAVVKVLG
TH_3989|M.thermoresistible__bu      GDRGSGT--EIGKLIARLWTLRRMSLAIAVSLADGVA-QEVPAALVKDLG
MAV_2554|M.avium_104                PVPDDRTAADIGDLMARLISLRQLSLSVARTLTHGGD-AANQAALVKDLG
MAB_0597|M.abscessus_ATCC_1997      AKSNGAADDPAIRERLAQAYVGMRTMRAYALATMDEE-RPGQDNVSKLLW
MLBr_00737|M.leprae_Br4923          ISTFQSIQFMLADMAMKVEAARLIVYAAAARAERGEPDLGFISAASKCFA
                                                                                  * : 

Mb3592|M.bovis_AF2122/97            SELDVHLHQTALDLRGADG-------------ELAGPWTEGLLFALGGPI
Rv3562|M.tuberculosis_H37Rv         SELDVHLHQTALDLRGADG-------------ELAGPWTEGLLFALGGPI
MMAR_3511|M.marinum_M               TSTEGD-IAELADLADS---------HRPRDSEFAALVTAALDQRPGFTL
MUL_2757|M.ulcerans_Agy99           TSTESD-IAELADLADSTDLADSGAPHRPRDPEFAALVTAALDQRPGFTL
MSMEG_2879|M.smegmatis_MC2_155      TTTEGD-IADFADLHRGD--------DGALPQQARDLITAAVDQRPGFTL
Mvan_3917|M.vanbaalenii_PYR-1       TTTEGD-IAEYAHLMMDD----------DAGQQFSDMANAAVDQRPGFTL
Mflv_5166|M.gilvum_PYR-GCK          TSTEGD-IADFADLLTDA--------CAPDHGGYRAMLDDAVVQRPGFTL
TH_3989|M.thermoresistible__bu      TRFENE-IVTAAQLLLDLE-------PDPGGEGLPRLLAEAVLQAPGFTI
MAV_2554|M.avium_104                TLFEAESVGLIADLLEAA----------PPNSELEAMLNTAWLHKPMFTL
MAB_0597|M.abscessus_ATCC_1997      ANWHRDLGELAMEIIGTST--------LLTNAGEMDEWQRLFLFSRADTI
MLBr_00737|M.leprae_Br4923          SDIAMEVTTDAVQLFGGAG------------YTSDFPVERFMRDAKITQI
                                    :    .      .:                                   :

Mb3592|M.bovis_AF2122/97            YAGTNEIQRNIIAERLLGLPREKT
Rv3562|M.tuberculosis_H37Rv         YAGTNEIQRNIIAERLLGLPREKT
MMAR_3511|M.marinum_M               RGGTNEVLRGVIAR-GLGLR----
MUL_2757|M.ulcerans_Agy99           RGGTNEVLRGVIAR-GLGLR----
MSMEG_2879|M.smegmatis_MC2_155      RGGTNEVLRGVIAR-GLGLR----
Mvan_3917|M.vanbaalenii_PYR-1       RGGTNEVLRGVIAR-GLGIR----
Mflv_5166|M.gilvum_PYR-GCK          RGGTNEILRGVIAR-GLGMR----
TH_3989|M.thermoresistible__bu      RGGTSEVLRSMVAR-GMGLR----
MAV_2554|M.avium_104                RGGTNEVLRGVIAR-GMGLR----
MAB_0597|M.abscessus_ATCC_1997      YGGSNEIQRNIISERVLGLPREAR
MLBr_00737|M.leprae_Br4923          YEGTNQIQRVVMSRALLR------
                                      *:.:: * :::.  :