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MTAVVDSRVQPAAPVSPRVRRGAILALALGGFGIGTTEFVAMGLLPNIAHGLHVTEPQAGHVISAYALGV VVGAPVIAALTARASRRTLLVALMVAFTIGNAATVFAPGYAALIASRFVAGLPHGAYFGVAALVAAHLAG PGERAKAVGQTMLGLSVANVVGVPVATWLGNTVGWRSAFAVVAVIGAITIAALLRYLPGLTDMRITNPLT ELGALRRVQVWFTLLIGIVGFGGMFAFYTYISTTLTSVSGLPRALVPLALSLYGIGMVTGNVLGGWMADR SVVRAIAVGLVLVAAMLLIFAAVSRNPWAALALVFAVGVSGTSLVPALQTRLMDVADDAQTLAAALNHSA LNIANAGGAWLGGLVITAGYGYRAPSLVGAALAIAGLVVLGLSVLYARSRAVALPSRAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1429 | - | - | 100% (409) | major facilitator superfamily permease |
| M. abscessus ATCC 19977 | MAB_2983c | - | 2e-44 | 30.95% (378) | chloramphenicol resistance protein |
| M. abscessus ATCC 19977 | MAB_2706c | - | 2e-16 | 26.40% (394) | putative transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0197 | - | 5e-30 | 29.34% (409) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_1840 | - | 1e-144 | 64.66% (399) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv0191 | - | 5e-30 | 29.34% (409) | integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0577 | - | 1e-34 | 29.02% (379) | integral membrane transport protein |
| M. avium 104 | MAV_4987 | - | 2e-27 | 27.30% (359) | sugar transporter family protein |
| M. smegmatis MC2 155 | MSMEG_5556 | - | 1e-141 | 63.64% (396) | MFS permease |
| M. thermoresistible (build 8) | TH_3988 | - | 3e-28 | 33.22% (283) | PUTATIVE putative MFS permease |
| M. ulcerans Agy99 | MUL_1084 | - | 1e-29 | 27.09% (406) | integral membrane protein |
| M. vanbaalenii PYR-1 | Mvan_4890 | - | 1e-144 | 65.08% (398) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1840|M.gilvum_PYR-GCK ---MSAAVDQQSTPGASVAAPDPVVRRLAVLALALGGFGIGTTEFVAMGL
Mvan_4890|M.vanbaalenii_PYR-1 ---MTDTLHRPSGP-VSVAAPDPVVRRLAVVALALGGFGIGTTEFVAMGL
MSMEG_5556|M.smegmatis_MC2_155 ---MTTSLQ-PNRP-ASVVATDTTVRWLAVFALALGGFGIGTAEFVAMGL
MAB_1429|M.abscessus_ATCC_1997 ---MTAVVDSRVQP---AAPVSPRVRRGAILALALGGFGIGTTEFVAMGL
Mb0197|M.bovis_AF2122/97 -------MTAPTGTSATTTRPWTPRIATQLSVLACAAFIYVTAEILPVGA
Rv0191|M.tuberculosis_H37Rv -------MTAPTGTSATTTRPWTPRIATQLSVLACAAFIYVTAEILPVGA
MUL_1084|M.ulcerans_Agy99 -------MTSEARTATTAARPWTPRVAAQLSVLAAAAFIYVTAEILPVGA
MAV_4987|M.avium_104 -------MTAET--ANAAARTWTPRIAAQLAILAAAAFTYVTAEILPVGA
MMAR_0577|M.marinum_M ----------MPESVTAPPELGIRHATPGLLALTIATCLAITTEILPVGL
TH_3988|M.thermoresistible__bu MSESKASQDASAPAADPVDATARRTPWIAILAAALGIFVMITIEELPIGV
: : . * * :.:*
Mflv_1840|M.gilvum_PYR-GCK LPDIARSFDVSEPVAGHVISAYALGVVVGAPLIAAITARMARRTLLLALM
Mvan_4890|M.vanbaalenii_PYR-1 LPDIATGMGVSEPTAGHVISAYALGVVVGAPVIAAVTARMARRKLLLALM
MSMEG_5556|M.smegmatis_MC2_155 LPDIATGFGITEPTAGHVISAYALGVVVGAPVLAAVTARVPRRVLLLGLM
MAB_1429|M.abscessus_ATCC_1997 LPNIAHGLHVTEPQAGHVISAYALGVVVGAPVIAALTARASRRTLLVALM
Mb0197|M.bovis_AF2122/97 LSAIARNLRVSVVLVGTLLSWYALVAAVTTVPLVRWTAHWPRRRALVVSL
Rv0191|M.tuberculosis_H37Rv LSAIARNLRVSVVLVGTLLSWYALVAAVTTVPLVRWTAHWPRRRALVVSL
MUL_1084|M.ulcerans_Agy99 LSAIARNLHISVVLVGTLLSWYALVAALTTVPLVRWTAHWPRRHALMVSL
MAV_4987|M.avium_104 LPAIARNLQVSLVLVGTLLSWYALVAALTTIPLVRWTAHLPRRRVLVASL
MMAR_0577|M.marinum_M LPAIGHTFGVRDAVTGLLVSLYAVLVALLAVPLTVVTARFPRKPLLLTTL
TH_3988|M.thermoresistible__bu LTLIGDDLGLSSGVVGLTVTIPGVLAGAVAVLTPTLIGRLDRRLALVSAL
*. *. : : .* :: .: . : .: *: *: :
Mflv_1840|M.gilvum_PYR-GCK AVFTLGNLASMLASSYETLVGARFLAGLPHGAYFGVAALVAAHLMGPQHR
Mvan_4890|M.vanbaalenii_PYR-1 ALFTIGNLASMLAPTYETLIAARFLAGLPHGAYFGVAALVAAHLMGPQNR
MSMEG_5556|M.smegmatis_MC2_155 AVFTLGNVASMVAPSYPTLVVARFVAGLPHGAYFGVAALAAAHLMGPANR
MAB_1429|M.abscessus_ATCC_1997 VAFTIGNAATVFAPGYAALIASRFVAGLPHGAYFGVAALVAAHLAGPGER
Mb0197|M.bovis_AF2122/97 VCLTVSQLVSALAPNFAVLAAGRVLCAVTHGLLWAVIAPIATRLVPPSHA
Rv0191|M.tuberculosis_H37Rv VCLTVSQLVSALAPNFAVLAAGRVLCAVTHGLLWAVIAPIATRLVPPSHA
MUL_1084|M.ulcerans_Agy99 VCLTISQLISALAPNFAVLAAGRALCAITHGLLWSVIAPIATRLVPPSHA
MAV_4987|M.avium_104 TCLTASQLISALAPNFAVLAAGRVLCAITHGLLWSVIAPIATRLVPPSHA
MMAR_0577|M.marinum_M LGYAVSNTLVAIAPTFAMVAAGRAVGGVTHALFFSLCIGYAPRLVGLADV
TH_3988|M.thermoresistible__bu LLVFVSAATSAIAPNLPVLLASRLFAGMAIGVFWALLAVVVARVAHPDDL
. .*. : .* . .:. . :.: ..:: .
Mflv_1840|M.gilvum_PYR-GCK AKAVAHVLTGLTVATVLGVPVASWLGQSLGWRAAFGLVVAVGVLTLTALA
Mvan_4890|M.vanbaalenii_PYR-1 AKAVAHVLTGLTVATVLGVPIASWLGQSLGWRAAFGLVVGVGLVTLTALW
MSMEG_5556|M.smegmatis_MC2_155 AKAVAHVLSGLTIATVLGVPMASWLGQALGWRSAFGLVVFVGVLTLAALW
MAB_1429|M.abscessus_ATCC_1997 AKAVGQTMLGLSVANVVGVPVATWLGNTVGWRSAFAVVAVIGAITIAALL
Mb0197|M.bovis_AF2122/97 GRATTSIYIGTSLALVVGSPLTAAMSLMWGWRLAAVCVTGAAAAVALAAR
Rv0191|M.tuberculosis_H37Rv GRATTSIYIGTSLALVVGSPLTAAMSLMWGWRLAAVCVTGAAAAVALAAR
MUL_1084|M.ulcerans_Agy99 GRATTSIYIGTSLALVIGSPLTAALSLMWGWRLAAVCVTVAAAVVTVAAR
MAV_4987|M.avium_104 GRATMSIYVGTSLALVVGSPLTAALSLMWGWRLAVVCVTVAAAVVTVAAR
MMAR_0577|M.marinum_M GRALALVGGGVSAGIVVGVPLLTSVGTAVGWRGAFAVLAVLAAVLLLVVA
TH_3988|M.thermoresistible__bu PKALTLAFGGVSVAVVLGVPFAAWIGAMVGWRWAFVLVGALGLMVAVALT
:* * : . *:* *. : :. *** * : . .
Mflv_1840|M.gilvum_PYR-GCK LWLPVQLRLMRSTSPLTELG-ALRRPQVWLALAVGMIGFGGMFAVYTYIA
Mvan_4890|M.vanbaalenii_PYR-1 CWLPFQLKFMRATSPLTELG-ALRRPQVWLALLVGMIGFGGMFAVYTYIT
MSMEG_5556|M.smegmatis_MC2_155 FWLPEQLRTMHISSPLTELG-ALRRPQVWLAVLVGMIGFGGMFAVYTYIS
MAB_1429|M.abscessus_ATCC_1997 RYLPG-LTDMRITNPLTELG-ALRRVQVWFTLLIGIVGFGGMFAFYTYIS
Mb0197|M.bovis_AF2122/97 LALPEMVLRADQLEHVGRRARHHRNPRLVKVSVLTMIAVTGHFVSYTYIV
Rv0191|M.tuberculosis_H37Rv LALPEMVLRADQLEHVGRRARHHRNPRLVKVSVLTMIAVTGHFVSYTYIV
MUL_1084|M.ulcerans_Agy99 LLLPEMVLSADQLQHVGPRSRHHRNRALIIVSLITMVGVTGHFVSYTYIV
MAV_4987|M.avium_104 LMLPEMVLTEHQLAHVGPRSRHHRNGRLITVSLLAMVAVTGHFVSYTFIV
MMAR_0577|M.marinum_M KLLPPVSSESAPPPAGTAKG----RRRLAAVVSSNALTYTGQFTLYTFIS
TH_3988|M.thermoresistible__bu VLLPPVPVAER--TTLGQLGAAWSIPAARTGVLVTLVMVTAHFTAYTYAS
** . : . *. **:
Mflv_1840|M.gilvum_PYR-GCK TTMTDVAGMPRALVPVALMVFGLGMFFGNLVGGRLADRSVVRALYLSMGA
Mvan_4890|M.vanbaalenii_PYR-1 TTMTDVAGMPRGLVPLALMMFGLGMVLGNLVGGRLADGSVVRALYLSLGA
MSMEG_5556|M.smegmatis_MC2_155 TTMTDVAGLSRGLVPLALMVFGFGMVIGNLLGGRLADLSVVRALYVSLAA
MAB_1429|M.abscessus_ATCC_1997 TTLTSVSGLPRALVPLALSLYGIGMVTGNVLGGWMADRSVVRAIAVGLVL
Mb0197|M.bovis_AF2122/97 VIIRDVVGVRGPNLAWLLAAYGVAGLVSVPLVARPLDRWPKGAVIVGMTG
Rv0191|M.tuberculosis_H37Rv VIIRDVVGVRGPNLAWLLAAYGVAGLVSVPLVARPLDRWPKGAVIVGMTG
MUL_1084|M.ulcerans_Agy99 VIIRQVVGVRGPSLAWLLAAYGVAGVVAVALVARPLDRRPKGTIIFCVAG
MAV_4987|M.avium_104 EIIRNVVGVRGPTLAWVLAAYGLAGLLSVPLVARPLDHRPKSAVILCMTG
MMAR_0577|M.marinum_M AVLLAAG-ARPAFIGPLLLMCGVCSLAGLWYVGATLDRNPRQTTVIIIVV
TH_3988|M.thermoresistible__bu PVLQDRIHITESGVGPMLFVFGIAGFLGNFAAGPLLRRSMRATYVVLPIG
: : * *. . . . : .
Mflv_1840|M.gilvum_PYR-GCK LCAMLTLFVAASH----NPWTALLA----LFGIGLTGSAVGPALQTRLMD
Mvan_4890|M.vanbaalenii_PYR-1 LCGALALFVVASH----NPWTALLV----LFLIGLTGSAVGPALQTRLMD
MSMEG_5556|M.smegmatis_MC2_155 LGILLAVFVAASH----HPWSALLV----LFGIGVAGSAVGPALQTRLMD
MAB_1429|M.abscessus_ATCC_1997 VAAMLLIFAAVSR----NPWAALAL----VFAVGVSGTSLVPALQTRLMD
Mb0197|M.bovis_AF2122/97 LTAAFTLLTALAFGERHTAATALLG-TGAIVLWGALATAVSPMLQSAAMR
Rv0191|M.tuberculosis_H37Rv LTAAFTLLTALAFGERHTAATALLG-TGAIVLWGALATAVSPMLQSAAMR
MUL_1084|M.ulcerans_Agy99 LTFAFVLLTALAFGGHLAPMTALVVGTGAIVLWGAAVTAVSPMLQSAAMR
MAV_4987|M.avium_104 LTAAFAVLTALAFGGPTGATTALIG-TAAIVLWGAMATAVSPMMQSAAMR
MMAR_0577|M.marinum_M VIGALLGLGASFP--------ALLPVVLAAAVWNGAFGGIPSIYQAGAVR
TH_3988|M.thermoresistible__bu VMVGVXXXGPNSR-------------------WRPDGTRM----------
: . :
Mflv_1840|M.gilvum_PYR-GCK VAHDAQTLAAALNHSALNIGNATGAWVGG-LVIAAGYGYTAPAGAG-AVL
Mvan_4890|M.vanbaalenii_PYR-1 VAHDAQTLAAALNHSALNIGNATGAWVGG-LVIAAGLGYTAPAAAG-AVL
MSMEG_5556|M.smegmatis_MC2_155 VAHDAQTLAAALNHSALNIGNATGAWVGG-LVIAAGFGYTAPAAAG-AVL
MAB_1429|M.abscessus_ATCC_1997 VADDAQTLAAALNHSALNIANAGGAWLGG-LVITAGYGYRAPSLVG-AAL
Mb0197|M.bovis_AF2122/97 SGGDDPDGASGLYVTAFQIGIMAGALLGG-LLYERSLAMMLTASAGLMGV
Rv0191|M.tuberculosis_H37Rv SGGDDPDGASGLYVTAFQIGIMAGALLGG-LLYERSLAMMLTASAGLMGV
MUL_1084|M.ulcerans_Agy99 SGADDPDGASGLYVTAFQVGIMAGSLIGG-LLYERSVAMMLTASAGLMGV
MAV_4987|M.avium_104 NGADDPDGASGLYVTAFQVGIMAGSLLGG-LLYERSVILMLSASGVLMAV
MMAR_0577|M.marinum_M AQAATPEMAGAWVNATANLGIAAGAAIGAGLLPTIGLAGLPWVAAALIAI
TH_3988|M.thermoresistible__bu --------------------------------------------------
Mflv_1840|M.gilvum_PYR-GCK ALAGLVVLTVSVVLQKR----------
Mvan_4890|M.vanbaalenii_PYR-1 ALAGLAVLTVSVLLQKRG---------
MSMEG_5556|M.smegmatis_MC2_155 AVGGLLVLTLSVAVQRRSKT-------
MAB_1429|M.abscessus_ATCC_1997 AIAGLVVLGLSVLYARSRAVALPSRAG
Mb0197|M.bovis_AF2122/97 ALFGMTVSQHLFENPTLSPGDG-----
Rv0191|M.tuberculosis_H37Rv ALFGMTVSQHLFENPTLSPGDG-----
MUL_1084|M.ulcerans_Agy99 ALVGMTSARRVFEAPVAVAGATSHNQ-
MAV_4987|M.avium_104 ALVGIAANRRMLDVAPTSSRDS-----
MMAR_0577|M.marinum_M SLAVTLATGRGPTH-------------
TH_3988|M.thermoresistible__bu ---------------------------