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M. thermoresistible (build 8) TH_3709 (-)

annotation: enoyl-CoA hydratase
coordinates: 1028526 - 1029335
length: 270

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3709--100% (270)enoyl-CoA hydratase
M. thermoresistible (build 8)TH_3065-e-13187.73% (269) PUTATIVE enoyl-CoA hydratase
M. thermoresistible (build 8)TH_4638-5e-6448.24% (255) PUTATIVE putative enoyl-CoA hydratase/isomerase family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2698echA153e-4141.23% (228) enoyl-CoA hydratase
M. gilvum PYR-GCKMflv_2395-9e-5141.15% (243) enoyl-CoA hydratase/isomerase
M. tuberculosis H37RvRv2679echA153e-4141.23% (228) enoyl-CoA hydratase
M. leprae Br4923MLBr_02402-3e-2628.92% (249) enoyl-CoA hydratase
M. abscessus ATCC 19977MAB_2737c-5e-2730.23% (258) enoyl-CoA hydratase
M. marinum MMMAR_4790-4e-5946.77% (248) enoyl-CoA hydratase
M. avium 104MAV_2558-1e-13791.45% (269) enoyl-CoA hydratase
M. smegmatis MC2 155MSMEG_5620-2e-6044.62% (251) enoyl-CoA hydratase
M. ulcerans Agy99MUL_0359-4e-5946.37% (248) enoyl-CoA hydratase
M. vanbaalenii PYR-1Mvan_4253-3e-5141.87% (246) enoyl-CoA hydratase/isomerase

CLUSTAL 2.0.9 multiple sequence alignment


Mb2698|M.bovis_AF2122/97            ----MPVTYDDFPSLRCEIHDQPGHEGVLELVLDSPGLNSVGPHMHRDLA
Rv2679|M.tuberculosis_H37Rv         ----MPVTYDDFPSLRCEIHDQPGHEGVLELVLDSPGLNSVGPHMHRDLA
TH_3709|M.thermoresistible__bu      MTTSEIATLPGYEEFAPWLLVEKRGAVHVVSINRPEAFNAVNEEVHHAFA
MAV_2558|M.avium_104                MTTSEIATLPGYEEFAPWLLVEKRGNVHVVSINRPEAFNAVNEQVHHAFA
Mflv_2395|M.gilvum_PYR-GCK          -----MYGMP--DEID----VTADGDLRIITLNRPDDLNAVNDNLHVGLA
Mvan_4253|M.vanbaalenii_PYR-1       -----MYGMP--EEID----VRADGALRIITLNRPDDLNAVNDNLHVGLA
MMAR_4790|M.marinum_M               -----MYDMP--TEID----VRAEGALRIITLNRPDALNAVNDNLHVGLA
MUL_0359|M.ulcerans_Agy99           -----MYDMP--TEID----VRAEGALRIITLNRPDALNAVNDNLHVGLA
MSMEG_5620|M.smegmatis_MC2_155      ----MNYDVP--DELS----VSTDGPVRIVTINRETDLNSVNEKLHWALA
MLBr_02402|M.leprae_Br4923          ------------MKYDTILVDG-YQRVGIITLNRPQALNALNSQMMNEIT
MAB_2737c|M.abscessus_ATCC_199      --------------MSFVLVDRPRPEIALVTLNRPERMNAMAFDVMLPFK
                                                                :  :     :*::  .:   : 

Mb2698|M.bovis_AF2122/97            DIWPVIDRDPAVRVVLVRGEGKAFSSGGSFDLIAETIGDYQGRLRIMREA
Rv2679|M.tuberculosis_H37Rv         DIWPVIDRDPAVRVVLVRGEGKAFSSGGSFDLIAETIGDYQGRLRIMREA
TH_3709|M.thermoresistible__bu      TIWRRLTDDEDVRAVVTTGVGKAFSAGGDMVMFGRLIEDPVARQFQITEA
MAV_2558|M.avium_104                TIWRVLTADDDVRAVVTTGVGKAFSAGGDMVMFGRLIDDAVARQFQISEA
Mflv_2395|M.gilvum_PYR-GCK          KIWEELNEDPGARAAVITGAGRAFSAGGDFHYLDELRRDEALRQKTIKHG
Mvan_4253|M.vanbaalenii_PYR-1       KIWEELNEDAGARAAVITGAGRAFSAGGDFNYLDELRNDEALRQKTIKHG
MMAR_4790|M.marinum_M               GLWRRLSEDRSARAAVLTGAGRAFSAGGDFAYLAELSQDADLRAKTIAHG
MUL_0359|M.ulcerans_Agy99           GLWRRLSEDRSARAAVLTGAGRAFSAGGDFAYLAELAQDADLRAKTIAHG
MSMEG_5620|M.smegmatis_MC2_155      NVWRQLAADKDAKVVVLTGAGRAFSAGGDLGWITTFLDDPVARDESIREG
MLBr_02402|M.leprae_Br4923          NAAKELDIDPDVGAILITGSPKVFAAGADIKEMASLTFTDAFDADFFSAW
MAB_2737c|M.abscessus_ATCC_199      QMLVDISHDNDVRAVVITGAGKGFCSGADQKSAGPIPHIGGLTQPTIALR
                                         :  *  . . :  *  : *.:*..                 :   

Mb2698|M.bovis_AF2122/97            R-----DLVLNLVNFDKPVVSAIRGPAVGAGLVVALLADISVAGRAAKII
Rv2679|M.tuberculosis_H37Rv         R-----DLVLNLVNFDKPVVSAIRGPAVGAGLVVALLADISVAGRAAKII
TH_3709|M.thermoresistible__bu      R-----TVFLEVINFPKPLVSAVNGPAVGLGCSIALLSDFLVMGRSSYLA
MAV_2558|M.avium_104                R-----TVFLEVINFPKPLVSAVNGPAVGLGCSIALLSDFLVMGESSYLA
Mflv_2395|M.gilvum_PYR-GCK          R-----DLVIGMVRCRIPVIAAVNGPAVGLGCSLAALSDVVYIAENAFFA
Mvan_4253|M.vanbaalenii_PYR-1       R-----DLVIGMVRCRIPVVAAVNGPAVGLGCSLAALSDVVYIAENAFFA
MMAR_4790|M.marinum_M               R-----DIVLGMARCRVPVVAAVNGPAVGLGCSLVALSDIVYIAPDAYLA
MUL_0359|M.ulcerans_Agy99           R-----DIVLGMARCRVPVVAAVNGPAVGLGCSLVALSDIVYIAPDAYLA
MSMEG_5620|M.smegmatis_MC2_155      A-----QIIEEMLRFPLPVIAAVNGPAVGLGCSVALLCDILLISEDAYLA
MLBr_02402|M.leprae_Br4923          G---------KLAAVRTPMIAAVAGYALGGGCELAMMCDLLIAADTAKFG
MAB_2737c|M.abscessus_ATCC_199      SMELLDEVILTLRRMHQPVIAAINGAAIGGGLCLALACDVRVASQDAYFR
                                               :     *:::*: * *:* *  :.  .*.   .  : : 

Mb2698|M.bovis_AF2122/97            DGHTKLGVAAGDHAA-ICWPLLVGMAKAKYYLLTCEPLSGEEAERIGLVS
Rv2679|M.tuberculosis_H37Rv         DGHTKLGVAAGDHAA-ICWPLLVGMAKAKYYLLTCEPLSGEEAERIGLVS
TH_3709|M.thermoresistible__bu      DPHVAVGLVAGDGGA-AMLPLLIGLMKAKQYVLLGDRITPEEAEKLNLVT
MAV_2558|M.avium_104                DPHVAVGLVAGDGGA-AMLPLLIGLMKAKEYVLLGDRITPAIADKLNLVT
Mflv_2395|M.gilvum_PYR-GCK          DPHVSIGLVAADGGP-LVWGSQISLLQAKEFALTGVRIKAQKAVELGLAN
Mvan_4253|M.vanbaalenii_PYR-1       DPHVSIGLVAADGGP-LVWGSQISLLQAKEFALTGVRIKAQRAVELGLAN
MMAR_4790|M.marinum_M               DPHVQVGLVAADGGP-LTWPLHISLMLAKEYALTGQRIAAQRAVELGLVN
MUL_0359|M.ulcerans_Agy99           DPHVQVGLVAADGGP-LTWPLHISLMLAKEYALTGQRIAAQRAVELGLAN
MSMEG_5620|M.smegmatis_MC2_155      DPHVSVGLVAGDGGA-ALWPLLTPIMRSREFLYTGDRIDAGKAVELGLAS
MLBr_02402|M.leprae_Br4923          QPEIKLGVLP-GMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVS
MAB_2737c|M.abscessus_ATCC_199      AAGINNGLTASELGLSYLLPRAIGTSRASDIMLTGRDVDADEAERIGLVS
                                          *: .   .             :         :    * . .*..

Mb2698|M.bovis_AF2122/97            ICVDDDDVLPTATRLAERLAAGAQNAIRWTKRSLN-HWYRMFGP--AFET
Rv2679|M.tuberculosis_H37Rv         ICVDDDDVLPTATRLAERLAAGAQNAIRWTKRSLN-HWYRMFGP--AFET
TH_3709|M.thermoresistible__bu      KVAEDDAVLDDALAIGERLAALPPQALRATKVAMNMHLSRAALG--ILEY
MAV_2558|M.avium_104                KVATDDTVLDEALAIGERLAGLPPQALRASKVAMNMHLSRAALG--VLEY
Mflv_2395|M.gilvum_PYR-GCK          HVVD--DPVGEAIACAKKIMALPQQAVEATKRLMNIQLEKSVMA--SLDY
Mvan_4253|M.vanbaalenii_PYR-1       HVVD--DPVAEAIACAKKLIELPQQAVEATKRLMNIQLEKSVMA--SLDY
MMAR_4790|M.marinum_M               HVAA--DPVAEAVACAQRIMKLPQQAVESTKRVLNIHLERAVLA--SLDY
MUL_0359|M.ulcerans_Agy99           HVAA--DPVAEAVACAQRIVKLPQQAVESTKRVLNIHLERAVLA--SLDY
MSMEG_5620|M.smegmatis_MC2_155      RSVAPGQLRSEAMTLAHRLAKQPVEALQGTKRVVNMYLSQVLSG--PLQA
MLBr_02402|M.leprae_Br4923          RVVLADDLLPEAKAVATTISQMSRSATRMAKEAVNRSFESTLAEGLLHER
MAB_2737c|M.abscessus_ATCC_199      RKVASESLLEECYAIGERIAGFSRPGIELTKRTIWSGLDAASLESHMHQE
                                      .        .   .  :   .  . . :*  :              : 

Mb2698|M.bovis_AF2122/97            SLGLEFIGFGGPDVREGLAAHREKRPARFGADPDPGAGS
Rv2679|M.tuberculosis_H37Rv         SLGLEFIGFGGPDVREGLAAHREKRPARFGADPDPGAGS
TH_3709|M.thermoresistible__bu      ALAEEYTSFTTPEFQERVAAFRAKSNK------------
MAV_2558|M.avium_104                ALAEEYTSFSTPEFKERVAAFRARSKK------------
Mflv_2395|M.gilvum_PYR-GCK          ANLAEYVSFGTADFNRIVDGLIAKN--------------
Mvan_4253|M.vanbaalenii_PYR-1       ANLAEYVSFGTADFNKIVDGLIAKK--------------
MMAR_4790|M.marinum_M               ALSAEHQSFTTEDFRSIVTRLTAPKN-------------
MUL_0359|M.ulcerans_Agy99           ALSAEHQSFTTEDFRSIVTRLTAPKN-------------
MSMEG_5620|M.smegmatis_MC2_155      GFAAEQVSMRSDDHRARLLAFKKKAHK------------
MLBr_02402|M.leprae_Br4923          --RLFHSTFVTDDQSEGMAAFIEKRAPQFTHR-------
MAB_2737c|M.abscessus_ATCC_199      GLGQLYVRLLTDNFEEATAARKEKRPAEFRDKR------
                                            :   :