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M. thermoresistible (build 8) TH_3065 (-)

annotation: enoyl-CoA hydratase
coordinates: 3968577 - 3969386
length: 270

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3065--100% (270)enoyl-CoA hydratase
M. thermoresistible (build 8)TH_3709-e-13187.73% (269) PUTATIVE enoyl-CoA hydratase
M. thermoresistible (build 8)TH_4638-1e-6449.02% (255) PUTATIVE putative enoyl-CoA hydratase/isomerase family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2698echA153e-3938.17% (241) enoyl-CoA hydratase
M. gilvum PYR-GCKMflv_2395-3e-5342.80% (243) enoyl-CoA hydratase/isomerase
M. tuberculosis H37RvRv2679echA153e-3938.17% (241) enoyl-CoA hydratase
M. leprae Br4923MLBr_02402-1e-2528.69% (251) enoyl-CoA hydratase
M. abscessus ATCC 19977MAB_1185c-2e-2729.27% (246) enoyl-CoA hydratase
M. marinum MMMAR_4790-2e-5846.53% (245) enoyl-CoA hydratase
M. avium 104MAV_2558-1e-13087.73% (269) enoyl-CoA hydratase
M. smegmatis MC2 155MSMEG_5620-1e-6145.02% (251) enoyl-CoA hydratase
M. ulcerans Agy99MUL_0359-2e-5846.53% (245) enoyl-CoA hydratase
M. vanbaalenii PYR-1Mvan_4253-3e-5343.09% (246) enoyl-CoA hydratase/isomerase

CLUSTAL 2.0.9 multiple sequence alignment


Mb2698|M.bovis_AF2122/97            -------MPVTYDDFPSLRCEIHDQPGHEGVLELVLDSPGLNSVGPHMHR
Rv2679|M.tuberculosis_H37Rv         -------MPVTYDDFPSLRCEIHDQPGHEGVLELVLDSPGLNSVGPHMHR
TH_3065|M.thermoresistible__bu      ---MTNSKIATLPRYEEFAPWLLVEKRGGVHVVSINRPQAFNAVNEEVHH
MAV_2558|M.avium_104                ---MTTSEIATLPGYEEFAPWLLVEKRGNVHVVSINRPEAFNAVNEQVHH
Mflv_2395|M.gilvum_PYR-GCK          --------MYGMP--DEID----VTADGDLRIITLNRPDDLNAVNDNLHV
Mvan_4253|M.vanbaalenii_PYR-1       --------MYGMP--EEID----VRADGALRIITLNRPDDLNAVNDNLHV
MMAR_4790|M.marinum_M               --------MYDMP--TEID----VRAEGALRIITLNRPDALNAVNDNLHV
MUL_0359|M.ulcerans_Agy99           --------MYDMP--TEID----VRAEGALRIITLNRPDALNAVNDNLHV
MSMEG_5620|M.smegmatis_MC2_155      -------MNYDVP--DELS----VSTDGPVRIVTINRETDLNSVNEKLHW
MLBr_02402|M.leprae_Br4923          ---MKYDTIL-------------VDGYQRVGIITLNRPQALNALNSQMMN
MAB_1185c|M.abscessus_ATCC_199      MTSHNFETIL-------------TERIDRVAVITLNRPKALNALNSQVMN
                                                                   :  :     :*::. .:  

Mb2698|M.bovis_AF2122/97            DLADIWPVIDRDPAVRVVLVRGEGKAFSSGGSFDLIAETIGDYQGRLRIM
Rv2679|M.tuberculosis_H37Rv         DLADIWPVIDRDPAVRVVLVRGEGKAFSSGGSFDLIAETIGDYQGRLRIM
TH_3065|M.thermoresistible__bu      AFATIWRALAADNDVRAVVTTGVGKAFSAGGDMAMFDRLIEDPVARQHQI
MAV_2558|M.avium_104                AFATIWRVLTADDDVRAVVTTGVGKAFSAGGDMVMFGRLIDDAVARQFQI
Mflv_2395|M.gilvum_PYR-GCK          GLAKIWEELNEDPGARAAVITGAGRAFSAGGDFHYLDELRRDEALRQKTI
Mvan_4253|M.vanbaalenii_PYR-1       GLAKIWEELNEDAGARAAVITGAGRAFSAGGDFNYLDELRNDEALRQKTI
MMAR_4790|M.marinum_M               GLAGLWRRLSEDRSARAAVLTGAGRAFSAGGDFAYLAELSQDADLRAKTI
MUL_0359|M.ulcerans_Agy99           GLAGLWRRLSEDRSARAAVLTGAGRAFSAGGDFAYLAELAQDADLRAKTI
MSMEG_5620|M.smegmatis_MC2_155      ALANVWRQLAADKDAKVVVLTGAGRAFSAGGDLGWITTFLDDPVARDESI
MLBr_02402|M.leprae_Br4923          EITNAAKELDIDPDVGAILITGSPKVFAAGADIKEMASLTFTDAFDADFF
MAB_1185c|M.abscessus_ATCC_199      EVTTAAAEFDADHGIGAIIITGSEKAFAAGADIKEMSEQSFSDMFGSDFF
                                     .:     :  *    . :  *  :.*::*..:  :             :

Mb2698|M.bovis_AF2122/97            REARDLVLNLVNFDKPVVSAIRGPAVGAGLVVALLADISVAGRAAKIIDG
Rv2679|M.tuberculosis_H37Rv         REARDLVLNLVNFDKPVVSAIRGPAVGAGLVVALLADISVAGRAAKIIDG
TH_3065|M.thermoresistible__bu      TEARTVFLELINFAKPLVSAVNGPAVGLGCSIALLSDFLVMGQSSFLSDP
MAV_2558|M.avium_104                SEARTVFLEVINFPKPLVSAVNGPAVGLGCSIALLSDFLVMGESSYLADP
Mflv_2395|M.gilvum_PYR-GCK          KHGRDLVIGMVRCRIPVIAAVNGPAVGLGCSLAALSDVVYIAENAFFADP
Mvan_4253|M.vanbaalenii_PYR-1       KHGRDLVIGMVRCRIPVVAAVNGPAVGLGCSLAALSDVVYIAENAFFADP
MMAR_4790|M.marinum_M               AHGRDIVLGMARCRVPVVAAVNGPAVGLGCSLVALSDIVYIAPDAYLADP
MUL_0359|M.ulcerans_Agy99           AHGRDIVLGMARCRVPVVAAVNGPAVGLGCSLVALSDIVYIAPDAYLADP
MSMEG_5620|M.smegmatis_MC2_155      REGAQIIEEMLRFPLPVIAAVNGPAVGLGCSVALLCDILLISEDAYLADP
MLBr_02402|M.leprae_Br4923          SAWG----KLAAVRTPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQP
MAB_1185c|M.abscessus_ATCC_199      SAWG----KLGAVRTPTIAAVSGYALGGGCELAMMCDVIIAAENATFGQP
                                             :     * ::*: * *:* *  :. :.*.   .  : : : 

Mb2698|M.bovis_AF2122/97            HTKLGVAAGDHAAICWPLLVGMAKAKYYLLTCEPLSGEEAERIGLVSICV
Rv2679|M.tuberculosis_H37Rv         HTKLGVAAGDHAAICWPLLVGMAKAKYYLLTCEPLSGEEAERIGLVSICV
TH_3065|M.thermoresistible__bu      HVAVGLVAGDGGAAMLPLLIGLMKAKEYVLLGDRITAEAAVKLNLVTKVT
MAV_2558|M.avium_104                HVAVGLVAGDGGAAMLPLLIGLMKAKEYVLLGDRITPAIADKLNLVTKVA
Mflv_2395|M.gilvum_PYR-GCK          HVSIGLVAADGGPLVWGSQISLLQAKEFALTGVRIKAQKAVELGLANHVV
Mvan_4253|M.vanbaalenii_PYR-1       HVSIGLVAADGGPLVWGSQISLLQAKEFALTGVRIKAQRAVELGLANHVV
MMAR_4790|M.marinum_M               HVQVGLVAADGGPLTWPLHISLMLAKEYALTGQRIAAQRAVELGLVNHVA
MUL_0359|M.ulcerans_Agy99           HVQVGLVAADGGPLTWPLHISLMLAKEYALTGQRIAAQRAVELGLANHVA
MSMEG_5620|M.smegmatis_MC2_155      HVSVGLVAGDGGAALWPLLTPIMRSREFLYTGDRIDAGKAVELGLASRSV
MLBr_02402|M.leprae_Br4923          EIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVV
MAB_1185c|M.abscessus_ATCC_199      EIKLGVLPGMGGSQRLTRAIGKAKAMDMILTGRNMDAAEAERSGLVSRVV
                                    .  :*: ..  ..           :         :    * . .*..  .

Mb2698|M.bovis_AF2122/97            DDDDVLPTATRLAERLAAGAQNAIRWTKRSLN-HWYRMFGPAFETSLGLE
Rv2679|M.tuberculosis_H37Rv         DDDDVLPTATRLAERLAAGAQNAIRWTKRSLN-HWYRMFGPAFETSLGLE
TH_3065|M.thermoresistible__bu      SDESVLDEALAIGERLVALPSQALRATKVAMNMHLSRAALGVLEYALAEE
MAV_2558|M.avium_104                TDDTVLDEALAIGERLAGLPPQALRASKVAMNMHLSRAALGVLEYALAEE
Mflv_2395|M.gilvum_PYR-GCK          D--DPVGEAIACAKKIMALPQQAVEATKRLMNIQLEKSVMASLDYANLAE
Mvan_4253|M.vanbaalenii_PYR-1       D--DPVAEAIACAKKLIELPQQAVEATKRLMNIQLEKSVMASLDYANLAE
MMAR_4790|M.marinum_M               A--DPVAEAVACAQRIMKLPQQAVESTKRVLNIHLERAVLASLDYALSAE
MUL_0359|M.ulcerans_Agy99           A--DPVAEAVACAQRIVKLPQQAVESTKRVLNIHLERAVLASLDYALSAE
MSMEG_5620|M.smegmatis_MC2_155      APGQLRSEAMTLAHRLAKQPVEALQGTKRVVNMYLSQVLSGPLQAGFAAE
MLBr_02402|M.leprae_Br4923          LADDLLPEAKAVATTISQMSRSATRMAKEAVNRSFESTLAEGLLHERRLF
MAB_1185c|M.abscessus_ATCC_199      ATESLLDEAKAVAKTISEMSLSASMMAKEAVNRAFESSLAEGLLFERRIF
                                            *   .  :   . .*   :*  :*          :       

Mb2698|M.bovis_AF2122/97            FIGFGGPDVREGLAAHREKRPARFGADPDPGAGS
Rv2679|M.tuberculosis_H37Rv         FIGFGGPDVREGLAAHREKRPARFGADPDPGAGS
TH_3065|M.thermoresistible__bu      YTSFSTPEFKERVAAFRARSQK------------
MAV_2558|M.avium_104                YTSFSTPEFKERVAAFRARSKK------------
Mflv_2395|M.gilvum_PYR-GCK          YVSFGTADFNRIVDGLIAKN--------------
Mvan_4253|M.vanbaalenii_PYR-1       YVSFGTADFNKIVDGLIAKK--------------
MMAR_4790|M.marinum_M               HQSFTTEDFRSIVTRLTAPKN-------------
MUL_0359|M.ulcerans_Agy99           HQSFTTEDFRSIVTRLTAPKN-------------
MSMEG_5620|M.smegmatis_MC2_155      QVSMRSDDHRARLLAFKKKAHK------------
MLBr_02402|M.leprae_Br4923          HSTFVTDDQSEGMAAFIEKRAPQFTHR-------
MAB_1185c|M.abscessus_ATCC_199      HSAFGTADQSEGMAAFVEKRPANFIHR-------
                                       :   :    :