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YDMPTEIDVRAEGALRIITLNRPDALNAVNDNLHVGLAGLWRRLSEDRSARAAVLTGAGRAFSAGGDFAY LAELSQDADLRAKTIAHGRDIVLGMARCRVPVVAAVNGPAVGLGCSLVALSDIVYIAPDAYLADPHVQVG LVAADGGPLTWPLHISLMLAKEYALTGQRIAAQRAVELGLVNHVAADPVAEAVACAQRIMKLPQQAVEST KRVLNIHLERAVLASLDYALSAEHQSFTTEDFRSIVTRLTAPKN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4790 | - | - | 100% (255) | enoyl-CoA hydratase |
| M. marinum M | MMAR_2037 | echA15 | 1e-29 | 32.90% (231) | enoyl-CoA hydratase EchA15 |
| M. marinum M | MMAR_3510 | echA8_5 | 1e-25 | 35.14% (222) | enoyl-CoA hydratase, EchA8_5 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2698 | echA15 | 3e-30 | 33.76% (234) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_2395 | - | 1e-101 | 71.83% (252) | enoyl-CoA hydratase/isomerase |
| M. tuberculosis H37Rv | Rv2679 | echA15 | 3e-30 | 33.76% (234) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 5e-24 | 32.47% (231) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_0836c | - | 4e-23 | 32.27% (251) | putative enoyl-CoA hydratase/isomerase |
| M. avium 104 | MAV_0867 | - | 1e-122 | 86.27% (255) | enoyl-CoA hydratase/isomerase family protein |
| M. smegmatis MC2 155 | MSMEG_4873 | - | 1e-110 | 77.38% (252) | enoyl-CoA hydratase/isomerase |
| M. thermoresistible (build 8) | TH_2529 | - | 1e-114 | 79.22% (255) | PUTATIVE enoyl-CoA hydratase/isomerase |
| M. ulcerans Agy99 | MUL_0359 | - | 1e-140 | 98.82% (255) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_4253 | - | 1e-103 | 72.83% (254) | enoyl-CoA hydratase/isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4790|M.marinum_M -------MYDMPTEIDVRAEGALRIITLNRPDALNAVNDNLHVGLAGLWR
MUL_0359|M.ulcerans_Agy99 -------MYDMPTEIDVRAEGALRIITLNRPDALNAVNDNLHVGLAGLWR
MAV_0867|M.avium_104 -------MYDMPTEIDVRADGALRIITLNRPDSLNSVNDDLHVGLARLWQ
MSMEG_4873|M.smegmatis_MC2_155 ----------MPDEIEVRAEGDIRVITLNRPEALNAVNDSLHEGLAHLWT
TH_2529|M.thermoresistible__bu -------MYDMPPEIDVRADGDIRIITLNRPDALNAVNDPLHEGLAKLWD
Mflv_2395|M.gilvum_PYR-GCK -------MYGMPDEIDVTADGDLRIITLNRPDDLNAVNDNLHVGLAKIWE
Mvan_4253|M.vanbaalenii_PYR-1 -------MYGMPEEIDVRADGALRIITLNRPDDLNAVNDNLHVGLAKIWE
MLBr_02402|M.leprae_Br4923 ---------MKYDTILVDGYQRVGIITLNRPQALNALNSQMMNEITNAAK
MAB_0836c|M.abscessus_ATCC_199 --------MSAARELLVERDGPVVILTMNRPHRRNALSTNMVSQFAAAWD
Mb2698|M.bovis_AF2122/97 MPVTYDDFPSLRCEIHDQPGHEGVLELVLDSPGLNSVGPHMHRDLADIWP
Rv2679|M.tuberculosis_H37Rv MPVTYDDFPSLRCEIHDQPGHEGVLELVLDSPGLNSVGPHMHRDLADIWP
: : : . *::. : ::
MMAR_4790|M.marinum_M RLSEDRSARAAVLTGAGRAFSAGGDFAYLAELSQDADLRAKTIAHGRDIV
MUL_0359|M.ulcerans_Agy99 RLSEDRSARAAVLTGAGRAFSAGGDFAYLAELAQDADLRAKTIAHGRDIV
MAV_0867|M.avium_104 RLTDDPTARAAVITGAGRAFSAGGDFGYLKELSADADLRAKTIRDGREIV
MSMEG_4873|M.smegmatis_MC2_155 RLSEDYDARAAVITGAGRAFSAGGDFAYLQELGEDPKLRAKTILHGREIV
TH_2529|M.thermoresistible__bu RLSEDYDARAAVLTGAGRAFSAGGDYAYLAELGEDPRLRAKTLQHGREIV
Mflv_2395|M.gilvum_PYR-GCK ELNEDPGARAAVITGAGRAFSAGGDFHYLDELRRDEALRQKTIKHGRDLV
Mvan_4253|M.vanbaalenii_PYR-1 ELNEDAGARAAVITGAGRAFSAGGDFNYLDELRNDEALRQKTIKHGRDLV
MLBr_02402|M.leprae_Br4923 ELDIDPDVGAILITGSPKVFAAGADIKE--MASLTFTDAFDADFFSAWGK
MAB_0836c|M.abscessus_ATCC_199 EIDHDDGIRAAILTGAGSAYCVGGDLSDGWMVRDGSAPPLDPATIGKGLL
Mb2698|M.bovis_AF2122/97 VIDRDPAVRVVLVRGEGKAFSSGGSFDLIAETIGDYQGRLRIMREARDLV
Rv2679|M.tuberculosis_H37Rv VIDRDPAVRVVLVRGEGKAFSSGGSFDLIAETIGDYQGRLRIMREARDLV
: * . :: * .:. *.. .
MMAR_4790|M.marinum_M LGMARCRVPVVAAVNGPAVGLGCSLVALSDIVYIAPDAYLADPHVQVGLV
MUL_0359|M.ulcerans_Agy99 LGMARCRVPVVAAVNGPAVGLGCSLVALSDIVYIAPDAYLADPHVQVGLV
MAV_0867|M.avium_104 LGMARCRIPVVAAVNGPAVGLGCSLVALSDIVYIAENAYLADPHVQVGLV
MSMEG_4873|M.smegmatis_MC2_155 LGMTRCRVPVVAAVNGPAVGLGCSLVALSDIVYIAPQAYLADPHVQVGLV
TH_2529|M.thermoresistible__bu LGMTRCRVPVVAAVNGPAVGLGCSLVALSDIVYIAPDAYLADPHVQVGLV
Mflv_2395|M.gilvum_PYR-GCK IGMVRCRIPVIAAVNGPAVGLGCSLAALSDVVYIAENAFFADPHVSIGLV
Mvan_4253|M.vanbaalenii_PYR-1 IGMVRCRIPVVAAVNGPAVGLGCSLAALSDVVYIAENAFFADPHVSIGLV
MLBr_02402|M.leprae_Br4923 LAAVRT--PMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKLGVL
MAB_0836c|M.abscessus_ATCC_199 LSHTLTK-PLIAAVNGACLGGGCEMLQQTDIRVSDEHATFGLPEVQRGLV
Mb2698|M.bovis_AF2122/97 LNLVNFDKPVVSAIRGPAVGAGLVVALLADISVAGRAAKIIDGHTKLGVA
Rv2679|M.tuberculosis_H37Rv LNLVNFDKPVVSAIRGPAVGAGLVVALLADISVAGRAAKIIDGHTKLGVA
: . *:::*: * .:* * : *: * : . . *:
MMAR_4790|M.marinum_M AADGGPLTWPLHISLMLAKEYALTGQRIAAQRAVELGLVNHVA--ADPVA
MUL_0359|M.ulcerans_Agy99 AADGGPLTWPLHISLMLAKEYALTGQRIAAQRAVELGLANHVA--ADPVA
MAV_0867|M.avium_104 AADGGPLTWPLHISLLLAKEYALTGTRISAQRAVELGLANHVA--DDPVA
MSMEG_4873|M.smegmatis_MC2_155 AADGGPITWPLHISLLLAKEYALTGARIPAQRAVELGLANHLS--DDPVA
TH_2529|M.thermoresistible__bu AADGGPITWPLHISLLLAKEYALTGARIPAQRAVELGLANHLS--EDPVA
Mflv_2395|M.gilvum_PYR-GCK AADGGPLVWGSQISLLQAKEFALTGVRIKAQKAVELGLANHVV--DDPVG
Mvan_4253|M.vanbaalenii_PYR-1 AADGGPLVWGSQISLLQAKEFALTGVRIKAQRAVELGLANHVV--DDPVA
MLBr_02402|M.leprae_Br4923 PGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLADDLLP
MAB_0836c|M.abscessus_ATCC_199 PGAGSMVRLKRQIPYTKAMEMILTGEPLTAFEAYHFGLVGHVVPAGTALD
Mb2698|M.bovis_AF2122/97 AGDHAAICWPLLVGMAKAKYYLLTCEPLSGEEAERIGLVSICVDDDDVLP
Rv2679|M.tuberculosis_H37Rv AGDHAAICWPLLVGMAKAKYYLLTCEPLSGEEAERIGLVSICVDDDDVLP
.. . : * ** : . .* . **.. :
MMAR_4790|M.marinum_M EAVACAQRIMKLPQQAVESTKRVLNIHLERAVLASLDYALSAEHQSFTTE
MUL_0359|M.ulcerans_Agy99 EAVACAQRIVKLPQQAVESTKRVLNIHLERAVLASLDYALSAEHQSFTTE
MAV_0867|M.avium_104 EAIACAQKILELPQQAVESTKRVLNIHLERAVLASLDYALSAESQSFVTE
MSMEG_4873|M.smegmatis_MC2_155 EAIEAAQKMAKLPRQSLEATKRLLNLHMEQAVLATLDFGNTAEEQSFRTE
TH_2529|M.thermoresistible__bu DAVAAARKMSRMPRQALEATKRLLNIHMERAVMATLDYGNTAEAQSFETE
Mflv_2395|M.gilvum_PYR-GCK EAIACAKKIMALPQQAVEATKRLMNIQLEKSVMASLDYANLAEYVSFGTA
Mvan_4253|M.vanbaalenii_PYR-1 EAIACAKKLIELPQQAVEATKRLMNIQLEKSVMASLDYANLAEYVSFGTA
MLBr_02402|M.leprae_Br4923 EAKAVATTISQMSRSATRMAKEAVNRSFESTLAEGLLHERRLFHSTFVTD
MAB_0836c|M.abscessus_ATCC_199 KARSLADRIVRNGPLAVRNAKEAIVRSGWLAEEDARAIEARLTRPVITSA
Mb2698|M.bovis_AF2122/97 TATRLAERLAAGAQNAIRWTKRSLN-HWYRMFGPAFETSLGLEFIGFGGP
Rv2679|M.tuberculosis_H37Rv TATRLAERLAAGAQNAIRWTKRSLN-HWYRMFGPAFETSLGLEFIGFGGP
* * : : . :*. : :
MMAR_4790|M.marinum_M DFRSIVTRLTAPKN-------------
MUL_0359|M.ulcerans_Agy99 DFRSIVTRLTAPKN-------------
MAV_0867|M.avium_104 DFRSIVTKL-ADKN-------------
MSMEG_4873|M.smegmatis_MC2_155 DFKAIVAGLNARKN-------------
TH_2529|M.thermoresistible__bu DFRNIVAGLNARRN-------------
Mflv_2395|M.gilvum_PYR-GCK DFNRIVDGLIAKN--------------
Mvan_4253|M.vanbaalenii_PYR-1 DFNKIVDGLIAKK--------------
MLBr_02402|M.leprae_Br4923 DQSEGMAAFIEKRAPQFTHR-------
MAB_0836c|M.abscessus_ATCC_199 DAREGLAAFKEKREARFTGR-------
Mb2698|M.bovis_AF2122/97 DVREGLAAHREKRPARFGADPDPGAGS
Rv2679|M.tuberculosis_H37Rv DVREGLAAHREKRPARFGADPDPGAGS
* : .