For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_4638 (-)

annotation: putative enoyl-CoA hydratase/isomerase family protein
coordinates: 2954493 - 2955278
length: 262

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_4638 - - 100% (262) putative enoyl-CoA hydratase/isomerase family protein
M. thermoresistible (build 8) TH_3165 - 1e-70 51.00% (249) PUTATIVE putative enoyl-CoA hydratase
M. thermoresistible (build 8) TH_3065 - 1e-64 49.02% (255) PUTATIVE enoyl-CoA hydratase

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb2698 echA15 7e-32 34.76% (233) enoyl-CoA hydratase
M. gilvum PYR-GCK Mflv_2395 - 1e-58 47.37% (247) enoyl-CoA hydratase/isomerase
M. tuberculosis H37Rv Rv2679 echA15 7e-32 34.76% (233) enoyl-CoA hydratase
M. leprae Br4923 MLBr_02402 - 4e-24 30.68% (251) enoyl-CoA hydratase
M. abscessus ATCC 19977 MAB_0836c - 6e-27 35.81% (215) putative enoyl-CoA hydratase/isomerase
M. marinum M MMAR_4790 - 7e-59 48.76% (242) enoyl-CoA hydratase
M. avium 104 MAV_0867 - 7e-65 50.61% (247) enoyl-CoA hydratase/isomerase family protein
M. smegmatis MC2 155 MSMEG_5620 - 5e-61 47.98% (248) enoyl-CoA hydratase
M. ulcerans Agy99 MUL_0359 - 3e-59 49.17% (242) enoyl-CoA hydratase
M. vanbaalenii PYR-1 Mvan_4253 - 2e-58 47.56% (246) enoyl-CoA hydratase/isomerase

CLUSTAL 2.0.9 multiple sequence alignment


Mb2698|M.bovis_AF2122/97            MPVTYDDFPSLRCEIHDQPGHEGVLELVLDSP-GLNSVGPHMHRDLADIW
Rv2679|M.tuberculosis_H37Rv         MPVTYDDFPSLRCEIHDQPGHEGVLELVLDSP-GLNSVGPHMHRDLADIW
Mflv_2395|M.gilvum_PYR-GCK          ---MYG-MPDEIDVTADGD----LRIITLNRPDDLNAVNDNLHVGLAKIW
Mvan_4253|M.vanbaalenii_PYR-1       ---MYG-MPEEIDVRADGA----LRIITLNRPDDLNAVNDNLHVGLAKIW
MMAR_4790|M.marinum_M               ---MYD-MPTEIDVRAEGA----LRIITLNRPDALNAVNDNLHVGLAGLW
MUL_0359|M.ulcerans_Agy99           ---MYD-MPTEIDVRAEGA----LRIITLNRPDALNAVNDNLHVGLAGLW
MAV_0867|M.avium_104                ---MYD-MPTEIDVRADGA----LRIITLNRPDSLNSVNDDLHVGLARLW
MSMEG_5620|M.smegmatis_MC2_155      --MNYD-VPDELSVSTDGP----VRIVTINRETDLNSVNEKLHWALANVW
TH_4638|M.thermoresistible__bu      --MDYGRFAPTLLVTKDGP----VRILTMNRPDDLNSFNDDLHSAMRRIW
MLBr_02402|M.leprae_Br4923          ------MKYDTILVDGYQR----VGIITLNRPQALNALNSQMMNEITNAA
MAB_0836c|M.abscessus_ATCC_199      -----MSAARELLVERDGP----VVILTMNRPHRRNALSTNMVSQFAAAW
                                                           :  :.::     *:.. .:   :    

Mb2698|M.bovis_AF2122/97            PVIDRDPAVRVVLVRGEGKAFSSGGSFDLIAETIGDYQGRLRIMREARDL
Rv2679|M.tuberculosis_H37Rv         PVIDRDPAVRVVLVRGEGKAFSSGGSFDLIAETIGDYQGRLRIMREARDL
Mflv_2395|M.gilvum_PYR-GCK          EELNEDPGARAAVITGAGRAFSAGGDFHYLDELRRDEALRQKTIKHGRDL
Mvan_4253|M.vanbaalenii_PYR-1       EELNEDAGARAAVITGAGRAFSAGGDFNYLDELRNDEALRQKTIKHGRDL
MMAR_4790|M.marinum_M               RRLSEDRSARAAVLTGAGRAFSAGGDFAYLAELSQDADLRAKTIAHGRDI
MUL_0359|M.ulcerans_Agy99           RRLSEDRSARAAVLTGAGRAFSAGGDFAYLAELAQDADLRAKTIAHGRDI
MAV_0867|M.avium_104                QRLTDDPTARAAVITGAGRAFSAGGDFGYLKELSADADLRAKTIRDGREI
MSMEG_5620|M.smegmatis_MC2_155      RQLAADKDAKVVVLTGAGRAFSAGGDLGWITTFLDDPVARDESIREGAQI
TH_4638|M.thermoresistible__bu      DALIDDVDARAVVLTGAGRAFSSGGYLPNFARNNTDPVARRKDIREAERL
MLBr_02402|M.leprae_Br4923          KELDIDPDVGAILITGSPKVFAAGADIKE--MASLTFTDAFDADFFSAWG
MAB_0836c|M.abscessus_ATCC_199      DEIDHDDGIRAAILTGAGSAYCVGGDLSDGWMVRDGSAPPLDPATIGKGL
                                      :  *    . :: *   .:. *. :                   .   

Mb2698|M.bovis_AF2122/97            VLNLVNFDKPVVSAIRGPAVGAGLVVALLADISVAGRAAKIIDGHTKLGV
Rv2679|M.tuberculosis_H37Rv         VLNLVNFDKPVVSAIRGPAVGAGLVVALLADISVAGRAAKIIDGHTKLGV
Mflv_2395|M.gilvum_PYR-GCK          VIGMVRCRIPVIAAVNGPAVGLGCSLAALSDVVYIAENAFFADPHVSIGL
Mvan_4253|M.vanbaalenii_PYR-1       VIGMVRCRIPVVAAVNGPAVGLGCSLAALSDVVYIAENAFFADPHVSIGL
MMAR_4790|M.marinum_M               VLGMARCRVPVVAAVNGPAVGLGCSLVALSDIVYIAPDAYLADPHVQVGL
MUL_0359|M.ulcerans_Agy99           VLGMARCRVPVVAAVNGPAVGLGCSLVALSDIVYIAPDAYLADPHVQVGL
MAV_0867|M.avium_104                VLGMARCRIPVVAAVNGPAVGLGCSLVALSDIVYIAENAYLADPHVQVGL
MSMEG_5620|M.smegmatis_MC2_155      IEEMLRFPLPVIAAVNGPAVGLGCSVALLCDILLISEDAYLADPHVSVGL
TH_4638|M.thermoresistible__bu      AKAMLECELPIVAAVNGLAVGLGGSLAVMSDLVVMAEDAFISDPHVSVGL
MLBr_02402|M.leprae_Br4923          KLAAVRT--PMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKLGV
MAB_0836c|M.abscessus_ATCC_199      LLSHTLTK-PLIAAVNGACLGGGCEMLQQTDIRVSDEHATFGLPEVQRGL
                                             *:::*: * .:* *  :    *:      * :   . . *:

Mb2698|M.bovis_AF2122/97            AAGDHAAICWPLLVGMAKAKYYLLTCEPLSGEEAERIGLVSICVDDDDVL
Rv2679|M.tuberculosis_H37Rv         AAGDHAAICWPLLVGMAKAKYYLLTCEPLSGEEAERIGLVSICVDDDDVL
Mflv_2395|M.gilvum_PYR-GCK          VAADGGPLVWGSQISLLQAKEFALTGVRIKAQKAVELGLANHVVD--DPV
Mvan_4253|M.vanbaalenii_PYR-1       VAADGGPLVWGSQISLLQAKEFALTGVRIKAQRAVELGLANHVVD--DPV
MMAR_4790|M.marinum_M               VAADGGPLTWPLHISLMLAKEYALTGQRIAAQRAVELGLVNHVAA--DPV
MUL_0359|M.ulcerans_Agy99           VAADGGPLTWPLHISLMLAKEYALTGQRIAAQRAVELGLANHVAA--DPV
MAV_0867|M.avium_104                VAADGGPLTWPLHISLLLAKEYALTGTRISAQRAVELGLANHVAD--DPV
MSMEG_5620|M.smegmatis_MC2_155      VAGDGGAALWPLLTPIMRSREFLYTGDRIDAGKAVELGLASRSVAPGQLR
TH_4638|M.thermoresistible__bu      VAGDGGALTWPFMMSMLKAKEYILLGERITASEAERLGLANRVTPRERVV
MLBr_02402|M.leprae_Br4923          LPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLADDLL
MAB_0836c|M.abscessus_ATCC_199      VPGAGSMVRLKRQIPYTKAMEMILTGEPLTAFEAYHFGLVGHVVPAGTAL
                                     ..  .            :         : . .* . **..  .      

Mb2698|M.bovis_AF2122/97            PTATRLAERLAAGAQNAIRWTKRSLN-HWYRMFGPAFETSLGLEFIGFGG
Rv2679|M.tuberculosis_H37Rv         PTATRLAERLAAGAQNAIRWTKRSLN-HWYRMFGPAFETSLGLEFIGFGG
Mflv_2395|M.gilvum_PYR-GCK          GEAIACAKKIMALPQQAVEATKRLMNIQLEKSVMASLDYANLAEYVSFGT
Mvan_4253|M.vanbaalenii_PYR-1       AEAIACAKKLIELPQQAVEATKRLMNIQLEKSVMASLDYANLAEYVSFGT
MMAR_4790|M.marinum_M               AEAVACAQRIMKLPQQAVESTKRVLNIHLERAVLASLDYALSAEHQSFTT
MUL_0359|M.ulcerans_Agy99           AEAVACAQRIVKLPQQAVESTKRVLNIHLERAVLASLDYALSAEHQSFTT
MAV_0867|M.avium_104                AEAIACAQKILELPQQAVESTKRVLNIHLERAVLASLDYALSAESQSFVT
MSMEG_5620|M.smegmatis_MC2_155      SEAMTLAHRLAKQPVEALQGTKRVVNMYLSQVLSGPLQAGFAAEQVSMRS
TH_4638|M.thermoresistible__bu      EEAVALAHRLADQPAQALRDTKRAMNLHLLNAANMILPFALATESETFAS
MLBr_02402|M.leprae_Br4923          PEAKAVATTISQMSRSATRMAKEAVNRSFESTLAEGLLHERRLFHSTFVT
MAB_0836c|M.abscessus_ATCC_199      DKARSLADRIVRNGPLAVRNAKEAIVRSGWLAEEDARAIEARLTRPVITS
                                      *   *  :      * . :*. :                      :  

Mb2698|M.bovis_AF2122/97            PDVREGLAAHREKRPARFGADPDPGAGS
Rv2679|M.tuberculosis_H37Rv         PDVREGLAAHREKRPARFGADPDPGAGS
Mflv_2395|M.gilvum_PYR-GCK          ADFNRIVDGLIAKN--------------
Mvan_4253|M.vanbaalenii_PYR-1       ADFNKIVDGLIAKK--------------
MMAR_4790|M.marinum_M               EDFRSIVTRLTAPKN-------------
MUL_0359|M.ulcerans_Agy99           EDFRSIVTRLTAPKN-------------
MAV_0867|M.avium_104                EDFRSIVTKL-ADKN-------------
MSMEG_5620|M.smegmatis_MC2_155      DDHRARLLAFKKKAHK------------
TH_4638|M.thermoresistible__bu      EDVRRSVEKFLSKDASR-----------
MLBr_02402|M.leprae_Br4923          DDQSEGMAAFIEKRAPQFTHR-------
MAB_0836c|M.abscessus_ATCC_199      ADAREGLAAFKEKREARFTGR-------
                                     *    :

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_4638	-	-	100% (262)	putative enoyl-CoA hydratase/isomerase family protein
M. thermoresistible (build 8)	TH_3165	-	1e-70	51.00% (249)	PUTATIVE putative enoyl-CoA hydratase
M. thermoresistible (build 8)	TH_3065	-	1e-64	49.02% (255)	PUTATIVE enoyl-CoA hydratase