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M. thermoresistible (build 8) TH_3679 (-)

annotation: Carboxylesterase, type B
coordinates: 4344745 - 4346358
length: 538

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3679--100% (538)Carboxylesterase, type B
M. thermoresistible (build 8)TH_2744-6e-9541.97% (517) PUTATIVE Carboxylesterase, type B
M. thermoresistible (build 8)TH_0737lipT7e-8339.52% (496) Probable carboxylesterase LipT

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2071clipT3e-8138.17% (503) carboxylesterase LipT
M. gilvum PYR-GCKMflv_3419-0.064.67% (518) carboxylesterase, type B
M. tuberculosis H37RvRv2045clipT3e-8138.17% (503) carboxylesterase LipT
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3452c-6e-8039.13% (506) carboxylesterase LipT
M. marinum MMMAR_4363-0.062.21% (516) carboxylesterase
M. avium 104MAV_1226-0.064.13% (513) carboxylesterase superfamily protein
M. smegmatis MC2 155MSMEG_3667-0.065.13% (519) para-nitrobenzyl esterase
M. ulcerans Agy99MUL_2261lipT7e-8139.96% (503) carboxylesterase, LipT
M. vanbaalenii PYR-1Mvan_3172-0.065.84% (524) carboxylesterase, type B

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3419|M.gilvum_PYR-GCK          --------------MTAEATPRSSA---PVVDTSTGPVRG-----LDDGI
Mvan_3172|M.vanbaalenii_PYR-1       --------------MTADATTRSSAGGRPVVETTNGPVRG-----VDDGS
MSMEG_3667|M.smegmatis_MC2_155      ---------------MANAARIADG---PVAETGYGPVRG-----TDDGT
TH_3679|M.thermoresistible__bu      MPSTTPPDDRTPDDAPTRPAPAHSAVGSPVVDTVHGPVRG-----RDDGV
MMAR_4363|M.marinum_M               --------------MTSDIRRMASDG--YVVETAYGPVRGAEDGIAAAGS
MAV_1226|M.avium_104                ---------------------MAVDD--LVVETGYGPVR----GVPVDG-
Mb2071c|M.bovis_AF2122/97           -----------MALESATVGSMHERT--VRARTATGIVEG----FTRDG-
Rv2045c|M.tuberculosis_H37Rv        -----------MALESATVGSMHERT--VRARTATGIVEG----FTRDG-
MUL_2261|M.ulcerans_Agy99           ---------------------MHERT--VRARTATGVVEG----FTRDG-
MAB_3452c|M.abscessus_ATCC_199      ---------------------MAKKP--IRINTVNGTVEG----FTRGG-
                                                                    *  * *.         * 

Mflv_3419|M.gilvum_PYR-GCK          ---IKSWKGVPYAAAPVGELRWRAPEPPPAWTEPRDATRVGPVCPQP-TD
Mvan_3172|M.vanbaalenii_PYR-1       ---VKSWKAVRYAAAPVGELRWRAPEPPQAWSEPVDAGRVGPVCPQP-TD
MSMEG_3667|M.smegmatis_MC2_155      ---AKAWLGIRYARAPIGELRWRAPEPPASWHDVFDATRVGAVCPQA-TD
TH_3679|M.thermoresistible__bu      ---VKVWRGIRYAAAPVGGLRWRAPEPPQPWREPMDAIRVGPACPQP-AD
MMAR_4363|M.marinum_M               GVRTKSWKGIRYGAPPVGELRFRAPQPPQPWTEIADATAFGPVCPQP-VL
MAV_1226|M.avium_104                ---VKAWKGIRYAAPPIGDLRFRAPQPPERWTEVADATVFGPACPQP-VF
Mb2071c|M.bovis_AF2122/97           ---VHRWRSIPYARAPVGSLRFRAPQPAQPWPGVRHCHTFANCAPQQRRY
Rv2045c|M.tuberculosis_H37Rv        ---VHRWRSIPYARAPVGSLRFRAPQPAQPWPGVRHCHTFANCAPQQRRY
MUL_2261|M.ulcerans_Agy99           ---VHRWRSIPYARAPIGLLRFRAPRPPQPWSGVRHCHGFTHCSPQQRRY
MAB_3452c|M.abscessus_ATCC_199      ---VHRFRGIPYAEPPVGPLRLRAPRPALPWTGVRTCRAWGAASIQQHRY
                                        : : .: *. .*:* ** ***.*.  *     .      . *    

Mflv_3419|M.gilvum_PYR-GCK          PKIPLDLGAPQGEDFLSLNVWAPSGTQPGDRKPVMVWVHGGAYVLGSASQ
Mvan_3172|M.vanbaalenii_PYR-1       PRIPIDLGAPQGEDFLTLNIWAPSGTQPGDAKPVMVWIHGGAYILGSASQ
MSMEG_3667|M.smegmatis_MC2_155      ARIPIDLGGKQDEDSLVLNVWAPSGCRPGDRRPVMVWVHGGAYVLGSASQ
TH_3679|M.thermoresistible__bu      PRIPLDLGAAIGEDCLNLNVWASSDTEPGDRKPVLVWVHGGAYVIGAASQ
MMAR_4363|M.marinum_M               ANMPIDLGAPQDEDCLRLNIWAPANTAPGAAKPVMVWLHGGAYMLGSASQ
MAV_1226|M.avium_104                PNMPLDLGAPQGEDCLRLNVWASADTQPGDAKPVMVWLHGGAYVLGSSSQ
Mb2071c|M.bovis_AF2122/97           TVMGIGRYQTRSEDCLTLNVVTPEEPATQP-LPVMVFIHGGGYILGSSAT
Rv2045c|M.tuberculosis_H37Rv        TVMGIGRYQTRSEDCLTLNVVTPEEPATQP-LPVMVFIHGGGYILGSSAT
MUL_2261|M.ulcerans_Agy99           TMLGLGKYQPMSEDCLTLNVVAPEAPTHRP-LPVMVFIHGGGYILGSSAT
MAB_3452c|M.abscessus_ATCC_199      AIILPGKPQKLSEDCLTLNVVAPEGPVSGP-LPVMFFIHGGGYFLGSSAT
                                    . :  .     .** * **: :.         **:.::***.*.:*::: 

Mflv_3419|M.gilvum_PYR-GCK          PLYHGRAMAGAGDVIVVTVNYRLGALGFLELSTLD-DSGRFASNLGLRDV
Mvan_3172|M.vanbaalenii_PYR-1       PLYHGGTLASGGDAVVVTVNYRLGALGFLELSTLGADPERFATNLGLRDV
MSMEG_3667|M.smegmatis_MC2_155      PLCRGRVLASEGDVVVVTVNYRLGPFGFLDLSEYSSRAMRFDTNLGLRDV
TH_3679|M.thermoresistible__bu      PLYHGRELVRRGDVVLVTLNYRLGAFGFLELTALSSGRRRFDTNVGLRDV
MMAR_4363|M.marinum_M               ALYDGRRLASSGEVIVVTVNYRLGALGFLDLSSLSHAGRSFDSNVGLRDV
MAV_1226|M.avium_104                TLYDGRRLVSHGDVVVVTVNYRLGALGFLDLSSLNSAGRSFDSNVGLRDV
Mb2071c|M.bovis_AF2122/97           PIYDGAALARRG-CVYVSVNYRLGALGCLDLSSLSTPQITLDSNVYLRDL
Rv2045c|M.tuberculosis_H37Rv        PIYDGAALARRG-CVYVSVNYRLGALGCLDLSSLSTPQITLDSNVYLRDL
MUL_2261|M.ulcerans_Agy99           PIYDGAALARRG-CVYVSVNYRLGALGCLDLSSLSTPDIAIDGNLYLRDL
MAB_3452c|M.abscessus_ATCC_199      PLYDGASLARRG-CVYVSVNYRLGGLGCVDLSSLSDDKHTIDSNLYLRDL
                                    .:  *  :.  *  : *::***** :* ::*:  .     :  *: ***:

Mflv_3419|M.gilvum_PYR-GCK          LAALGWVRDNIAAFGGDPGRVTVFGESAGGGIVTSLLGSPAAAGLFHAAI
Mvan_3172|M.vanbaalenii_PYR-1       LAALEWVRDNIAAFGGDPGRVTVFGESAGGGIVASLLASPAAAGLFSAAI
MSMEG_3667|M.smegmatis_MC2_155      IFALQWVRDNIAAFGGDPSRVTLFGESAGGGMITTLLASPAAEGLFSAAI
TH_3679|M.thermoresistible__bu      LFALAWVRDNIAAFGGDPDRVTLFGESAGGGIVTTLLGSPAAAGLFHRAI
MMAR_4363|M.marinum_M               LAALHWVRENIAAFGGDPANITLFGESAGAGLVTTLLVTPAARGLFSRAI
MAV_1226|M.avium_104                LAALEWVRDNITAFGGDPRRVTLFGESAGAGIVTTLLASPAAAGLFAAAI
Mb2071c|M.bovis_AF2122/97           VLALRWVHDNIAEFGGDPGNVTIFGESAGAHITATLLAVPAAKGLFARAI
Rv2045c|M.tuberculosis_H37Rv        VLALRWVHDNIAEFGGDPGNVTIFGESAGAHITATLLAVPAAKGLFARAI
MUL_2261|M.ulcerans_Agy99           VMALQWIQDNIAEFGGDPDNVTIFGESAGAHITATLLAVPAAKGLFARAI
MAB_3452c|M.abscessus_ATCC_199      VLALQWVHDNIGAFGGDPNNVTIFGESAGSHAVNTLLAVPSAAGLFHRAI
                                    : ** *:::**  ***** .:*:******.    :**  *:* ***  **

Mflv_3419|M.gilvum_PYR-GCK          AQSSPATSMYDVGRARRVATRFLEVIGVDRADMS-ALTTAPISALVEASR
Mvan_3172|M.vanbaalenii_PYR-1       AQSAPVTSTYELGRAQRVAERFLDVLGARPDDLH-RLSEAPIDVLVEASR
MSMEG_3667|M.smegmatis_MC2_155      AQSSPATSVYDAERSRRVARALLERLLIEPDDAA-RLAHVPIPAILGASQ
TH_3679|M.thermoresistible__bu      AQSSPATSCYGTERAIDVAEQFLGHLGLSPRDVD-RLPDVPVAAIVEVSK
MMAR_4363|M.marinum_M               AQSSPATSVYDRERAQRVAVHLLDKLGVAASDVD-KLTQLPTAAIVAAST
MAV_1226|M.avium_104                AQSSPATSVYDRDRAARVAEAFLGKLGITASESR-RLIDMPMAAILAASQ
Mb2071c|M.bovis_AF2122/97           SESPAAGMVRSREVAAEFAARFANLIGARTQDAANALMQASPAQLVEAQH
Rv2045c|M.tuberculosis_H37Rv        SESPAAGMVRSREVAAEFAARFANLIGARTQDAANALMQASPAQLVEAQH
MUL_2261|M.ulcerans_Agy99           SESPAAGMVRPREIAAEFATRFARLLGARKHDAASALMRATAAQLVQTQH
MAB_3452c|M.abscessus_ATCC_199      CQSTASGLVVSAEDAAVNARQFAKYLGASDSNAAATVLAAKPKDLVKALF
                                    .:*..         :   *  :   :     :    :       :: .  

Mflv_3419|M.gilvum_PYR-GCK          TVFNEVPVRTPGTLAFAPTIDGDLLPDYPVNLARNGKTHPVPLLIGTNKN
Mvan_3172|M.vanbaalenii_PYR-1       TVFDEVPVRTPGTLAFAPTVDGDLLPDYPVNLARQGRTHPVPLIIGTNKN
MSMEG_3667|M.smegmatis_MC2_155      QIFNEVPAQSPGTLAFAPIVDGDVVPDYPVQAARAGRTHRVPLIIGTNKH
TH_3679|M.thermoresistible__bu      HVFDDVPARRPGTLAFAPIVDGDIVPDYPVALARAGRTLPVPLVIGTNKD
MMAR_4363|M.marinum_M               EVFNEVPVRNPGTLAFVPIVDGDVLTDYPVKVAQEGRSHPVPLLIGTNKH
MAV_1226|M.avium_104                QVFDEVPVRNPGTLAFVPIVDGDVLADYPVKVAQQGCSHPVPLIIGTNQH
Mb2071c|M.bovis_AF2122/97           HLIRQGMRKRLGAFPIGPVFGDDYLPMDPVEAMRSGRVHAVPLIVGTNAE
Rv2045c|M.tuberculosis_H37Rv        HLIRQGMRKRLGAFPIGPVFGDDYLPMDPVEAMRSGRVHAVPLIVGTNAE
MUL_2261|M.ulcerans_Agy99           RLIDQGMQKRLGAFPIGPTFGDDCLPLDPVEAMRAGQSHKVPLIVGTNAD
MAB_3452c|M.abscessus_ATCC_199      RLIGSAKHVPGLSLRIGPSIDGDVLPQDPIEAMERGESHRVPLIIGYNAE
                                     :: .       :: : * ...* :.  *:   . *    ***::* * .

Mflv_3419|M.gilvum_PYR-GCK          EAALFRYMKSPLMPVAPESVRAMFAEISAEQPTLQLPSEDHLRGIYRG-R
Mvan_3172|M.vanbaalenii_PYR-1       EAALFRYMKSPLMPIAPASIKAMFAEIAAEQPGLQLPSEDILKGTYRG-R
MSMEG_3667|M.smegmatis_MC2_155      EASLFRWMKSPLMPITPEAIRAMFEGIASEQPGLALPTEEEIRAAYSGMR
TH_3679|M.thermoresistible__bu      EASLFRWMKSPLLPITPDAIKKMFADIAAEQPGLRLPTETQISAAYRRQR
MMAR_4363|M.marinum_M               EAALFRLMRSPLMPITPRAITSMFTQIAAEQPDLQLPTEEEIGLAYSRLR
MAV_1226|M.avium_104                EAALFRLMRSALMPITPHAITSMFNQIAAEQPDLQLPTEKQIGSAYSRFR
Mb2071c|M.bovis_AF2122/97           EGRLFTRFLG-MLPTNEPMVEELLSGMKPA-------DRERITAAYPNYP
Rv2045c|M.tuberculosis_H37Rv        EGRLFTRFLG-MLPTNEPMVEELLSGMKPA-------DRERITAAYPNYP
MUL_2261|M.ulcerans_Agy99           EGRLFTRFLK-MLPTNKAMIDELLADTEPA-------TRERITAAYPNYP
MAB_3452c|M.abscessus_ATCC_199      EATLFTKVLK-ILPITPEALEHSLSKGGPD-------FVRRIIEGYDGYP
                                    *. **  .   ::*     :   :    .            :   *    

Mflv_3419|M.gilvum_PYR-GCK          GKNHALGLTSDLGFRMPSIWFADGHRAVAPVYLYRFDFATPLLRVARLHA
Mvan_3172|M.vanbaalenii_PYR-1       GKTKGLGLTSDLGFRMPSLWFADGHRAVAPVYLYRFDFHTPLLRLVRLHA
MSMEG_3667|M.smegmatis_MC2_155      TKAIGMGVARDIGFRMPTLWFADGHSTSAPVYLYRFDFATPMLRLLRLGA
TH_3679|M.thermoresistible__bu      GKRLGVGVASDIGFRMPSVWFAEGHTAVAPTYLYRFDWSTPTLRLLRLGA
MMAR_4363|M.marinum_M               RRARPLSIATDVGFRMPSVWLAEGHSRVAPVYLYRFDYSTPLLKLLLVRA
MAV_1226|M.avium_104                RRARYLSIATDVGFRMPSVWLAEGHARVAPVYLYRFDYSTPLLRLLMVKA
Mb2071c|M.bovis_AF2122/97           APSACIQLGGDFAFSSAAWQIAEAHGANAPTYLYRYDYAPRTLRWSGFGA
Rv2045c|M.tuberculosis_H37Rv        APSACIQLGGDFAFSSAAWQIAEAHGANAPTYLYRYDYAPRTLRWSGFGA
MUL_2261|M.ulcerans_Agy99           ESAACIQLGGDFAFNAAAWQIAEAQGVHAPTYLYRYDYAPRTLRWSGFGA
MAB_3452c|M.abscessus_ATCC_199      SQQALLQLAGDLAFGSAAWRVAEAHGRYAPTYFYRYDYTTRALRRYGLGP
                                         : :  *..*  .:  .*:.:   **.*:**:*: .  *:   . .

Mflv_3419|M.gilvum_PYR-GCK          AHATELPFVWGNLGSGRKDPTFALGGRKSGTAVSQRMQSRWTNFAANGDP
Mvan_3172|M.vanbaalenii_PYR-1       AHATELPFVWGNLVAGRRDPTFALGGRKSGAAVSERMRARWVSFAAHGAP
MSMEG_3667|M.smegmatis_MC2_155      AHATELPYVWGNLAAGPKDPTFKMGGLKQGRKVSQRIRRRWVNFATTGEP
TH_3679|M.thermoresistible__bu      AHATELPYVFGNLDT-PKDPTFTLGGRRTGRQVSQRIRTRWINFAVHGRP
MMAR_4363|M.marinum_M               AHATELPYVWGNLGG-PQDPTLRLGGAKTAKAVSKRMRTRWINFATQDNP
MAV_1226|M.avium_104                AHATELPYVWGTLGA-PKDPTLKLGGSKTAKAVSKRVRTRWTNFAAHAKP
Mb2071c|M.bovis_AF2122/97           THATELFAVFDIYRTRFGALLTAAADRRAALRVSNEVQRRWRCFSQIGVP
Rv2045c|M.tuberculosis_H37Rv        THATELFAVFDIYRTRFGALLTAAADRRAALRVSNEVQRRWRCFSQIGVP
MUL_2261|M.ulcerans_Agy99           THATELFAVFDIYRTRFGALLTAAADRRHALRVSDEVIRRWRSFSQTGTP
MAB_3452c|M.abscessus_ATCC_199      THAIELLAVFGTYRTVAGPFLAGRADRAVARSVSDEMQRRWLAFAHTGVP
                                    :** **  *:.             ..   .  **..:  **  *:    *

Mflv_3419|M.gilvum_PYR-GCK          SAPG-APTWRPYDAS-RATLVIDKHDSVVDDLDAHVRRAWGDDVLSFL
Mvan_3172|M.vanbaalenii_PYR-1       TGPAGEPVWRPYGADDRATLVIDKQDTVVDDLDADVRRAWGDDVLSFL
MSMEG_3667|M.smegmatis_MC2_155      TGALGEPVWRRYRREDRAALVIDKQDKTVTDLDQQLQAAWGDQVLNFR
TH_3679|M.thermoresistible__bu      DGPPGEPRWHAYDRAERPCLLIDRRDRVVRDVDEPIRLTWGSEVLSFR
MMAR_4363|M.marinum_M               AGPAGEPDWPAYQDGDRACLVIDKSDRVARDIDAPIRAAWGREVVGFR
MAV_1226|M.avium_104                AGPAGSPEWAPYQEQDRACLIIGKNDVLAHDVDAKARAAWGSEMVSFR
Mb2071c|M.bovis_AF2122/97           -----GDDWPAYTQDDRAVLVFDRRCRIEFDPHQHRRIAWDGFSLAN-
Rv2045c|M.tuberculosis_H37Rv        -----GDDWPAYTQDDRAVLVFDRRCRIEFDPHQHRRIAWDGFSLAN-
MUL_2261|M.ulcerans_Agy99           -----GEDWPAYTHTRRAVMVIDRKSRVEIDPHRHRRLAWDGFSLAR-
MAB_3452c|M.abscessus_ATCC_199      -----GDGWPAHTVPDRQVLIIDNPSRLEADPDADRRPLWQDVTSIV-
                                            *  :    *  :::..      * .   :  *