For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_2744 (-)

annotation: Carboxylesterase, type B
coordinates: 1160994 - 1162568
length: 525

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2744--100% (525)Carboxylesterase, type B
M. thermoresistible (build 8)TH_0737lipTe-10243.66% (497) Probable carboxylesterase LipT
M. thermoresistible (build 8)TH_3679-6e-9541.97% (517) PUTATIVE Carboxylesterase, type B

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2071clipT1e-9440.90% (511) carboxylesterase LipT
M. gilvum PYR-GCKMflv_3787-0.070.10% (495) carboxylesterase, type B
M. tuberculosis H37RvRv2045clipT1e-9440.90% (511) carboxylesterase LipT
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2866c-0.064.74% (519) carboxylesterase (LipT)
M. marinum MMMAR_4363-2e-9440.12% (511) carboxylesterase
M. avium 104MAV_2466-1e-9543.74% (487) LppT protein
M. smegmatis MC2 155MSMEG_3002-0.072.60% (500) para-nitrobenzyl esterase
M. ulcerans Agy99MUL_2261lipT3e-9343.06% (483) carboxylesterase, LipT
M. vanbaalenii PYR-1Mvan_2609-0.068.56% (493) carboxylesterase, type B

CLUSTAL 2.0.9 multiple sequence alignment


Mb2071c|M.bovis_AF2122/97           -----------------------MALESATVGSMHERTVRARTATGIVEG
Rv2045c|M.tuberculosis_H37Rv        -----------------------MALESATVGSMHERTVRARTATGIVEG
MAV_2466|M.avium_104                ---------------------------------MHDRTVRARTATGIVEG
MUL_2261|M.ulcerans_Agy99           ---------------------------------MHERTVRARTATGVVEG
TH_2744|M.thermoresistible__bu      ----VVLVSMRIPSLKVMG--SASHNYHAGVTAVVERSPIADTPLGRLRG
MSMEG_3002|M.smegmatis_MC2_155      ------------------------------MSVVAEHSTIAHTSLGTLRG
Mflv_3787|M.gilvum_PYR-GCK          ------------------------------MAIVDGDSTLVSTPSGDLRG
Mvan_2609|M.vanbaalenii_PYR-1       ---------------------------------------MLSTPSGDLRG
MAB_2866c|M.abscessus_ATCC_199      MYPEKTRGNFPAPPLRLCGPVTADRTTIRYVAVDVALPTVVRTPLGALRG
MMAR_4363|M.marinum_M               --------------------------MTSDIRRMASDGYVVETAYGPVRG
                                                                              *. * :.*

Mb2071c|M.bovis_AF2122/97           FTR--------DGVHRWRSIPYARAPVGSLRFRAPQPAQPWPGVRHCHTF
Rv2045c|M.tuberculosis_H37Rv        FTR--------DGVHRWRSIPYARAPVGSLRFRAPQPAQPWPGVRHCHTF
MAV_2466|M.avium_104                FTR--------DGVHRWRSIPYARPPVGDLRFRAPQPAQPWSGVRHCHGF
MUL_2261|M.ulcerans_Agy99           FTR--------DGVHRWRSIPYARAPIGLLRFRAPRPPQPWSGVRHCHGF
TH_2744|M.thermoresistible__bu      SYENVPAQAA-EGVAVWRGVPYARQPVGDLRFRAPEPPRPWSGVRDAVEP
MSMEG_3002|M.smegmatis_MC2_155      TLE--------AGVSVWRGVHYAQQPVGDLRFRAPQPLQPWSGVREAVEH
Mflv_3787|M.gilvum_PYR-GCK          DID--------GGVGVWRGVPYAEQPVGLRRFLAPAELAPWMGVRDAVEH
Mvan_2609|M.vanbaalenii_PYR-1       EVE--------AGIGVWRGIPYAEQPTGQRRFLAPEPMAPWPGVREAREH
MAB_2866c|M.abscessus_ATCC_199      AIEG--------GVSVWRGVPYAQQPVEQLRFLAPVPLEPWEGVRDAIEH
MMAR_4363|M.marinum_M               AEDGIAAAGSGVRTKSWKGIRYGAPPVGELRFRAPQPPQPWTEIADATAF
                                                    *:.: *.  *    ** **    **  : ..   

Mb2071c|M.bovis_AF2122/97           ANCAPQQRRYTVMGIG----RYQTRSEDCLTLNVVTPEE-PATQPLPVMV
Rv2045c|M.tuberculosis_H37Rv        ANCAPQQRRYTVMGIG----RYQTRSEDCLTLNVVTPEE-PATQPLPVMV
MAV_2466|M.avium_104                ANCAPQQRRYTLLGLSGLGGRYQPMSEDCLTLNVVTPEA-PAEGPLPVMV
MUL_2261|M.ulcerans_Agy99           THCSPQQRRYTMLGLG----KYQPMSEDCLTLNVVAPEA-PTHRPLPVMV
TH_2744|M.thermoresistible__bu      APIPPQGRSFVGGGKD----DPRIRDEACLTLTVWSPD---PGGSLPVMV
MSMEG_3002|M.smegmatis_MC2_155      GPLPPQGRSFVGGGRD----DPKMRDEACLTVTVWSPD---TSGALPVMV
Mflv_3787|M.gilvum_PYR-GCK          GPLPPQTKSFVGGGRD----DPKARDEACLTLTVWSPD---TTGSLPVMV
Mvan_2609|M.vanbaalenii_PYR-1       GPLPPQSKSFVGGGRD----DPKVRDEACLTLTVWSPD---TAASLPVMV
MAB_2866c|M.abscessus_ATCC_199      APLPPQGKSFVGAGRD----DPKIRGEECLTVTVWSPD---VHASLPVMV
MMAR_4363|M.marinum_M               GPVCPQP-VLANMPID----LGAPQDEDCLRLNIWAPANTAPGAAKPVMV
                                        **    .    .         .* ** :.: :*       . ****

Mb2071c|M.bovis_AF2122/97           FIHGGGYILGSSATPIYDGAALARRG-CVYVSVNYRLGALGCLDLSSLST
Rv2045c|M.tuberculosis_H37Rv        FIHGGGYILGSSATPIYDGAALARRG-CVYVSVNYRLGALGCLDLSSLST
MAV_2466|M.avium_104                FIHGGGYFLGSSATPLYDGAALARRG-CVYVSVNYRLGALGCVDFSSLST
MUL_2261|M.ulcerans_Agy99           FIHGGGYILGSSATPIYDGAALARRG-CVYVSVNYRLGALGCLDLSSLST
TH_2744|M.thermoresistible__bu      WIPGGAFVYGAGHLQLYNGSRLAANGNVVVVNVTYRLGVFGGFELSGLGA
MSMEG_3002|M.smegmatis_MC2_155      WIPGGAFVYGAGQLQLYNGSRLAANGNVVVVNVTYRLGVFGGFELGDLAG
Mflv_3787|M.gilvum_PYR-GCK          WIPGGAFVYGAGQFQLYNGSRLAANGDVVVVNVTYRIGVFGGFELSDLGE
Mvan_2609|M.vanbaalenii_PYR-1       WIPGGAFVYGAGQFQLYNGSRLAANGDVVVVNVTYRIGVFGGLELSDLGD
MAB_2866c|M.abscessus_ATCC_199      WIPGGAFVFGAGQLELYSGARLAANGNVVVVNVTYRLGALGGLELSALGE
MMAR_4363|M.marinum_M               WLHGGAYMLGSASQALYDGRRLASSGEVIVVTVNYRLGALGFLDLSSLSH
                                    :: **.:. *:.   :*.*  **  *  : *.*.**:*.:* .::. *. 

Mb2071c|M.bovis_AF2122/97           PQITLDSNVYLRDLVLALRWVHDNIAEFGGDPGNVTIFGESAGAHITATL
Rv2045c|M.tuberculosis_H37Rv        PQITLDSNVYLRDLVLALRWVHDNIAEFGGDPGNVTIFGESAGAHITATL
MAV_2466|M.avium_104                PEIPLESNLYLRDLVLALQWVRDNIAEFGGDPDNVTIFGESAGACITATL
MUL_2261|M.ulcerans_Agy99           PDIAIDGNLYLRDLVMALQWIQDNIAEFGGDPDNVTIFGESAGAHITATL
TH_2744|M.thermoresistible__bu      G---FDDNLALRDQVAALRWVRDNIAAFGGDPGRVTVFGESAGATSVLAL
MSMEG_3002|M.smegmatis_MC2_155      D---FSDNLCLRDQLAALQWVRDNIAAFGGDPKRVTVFGESAGATSVLAL
Mflv_3787|M.gilvum_PYR-GCK          G---FDDNLALRDQIAALRWVRDNIAAFGGDPGRVTVFGESAGATSVLAL
Mvan_2609|M.vanbaalenii_PYR-1       G---FDDNLALRDQIAALRWVRDNISAFGGDPGRVTVFGESAGATSVLAL
MAB_2866c|M.abscessus_ATCC_199      G---FDDNLALRDQMAALTWVRDNIAAFGGDPDHVTIFGESAGATSVLAL
MMAR_4363|M.marinum_M               AGRSFDSNVGLRDVLAALHWVRENIAAFGGDPANITLFGESAGAGLVTTL
                                        :..*: *** : ** *:::**: ***** .:*:*******  . :*

Mb2071c|M.bovis_AF2122/97           LAVPAAKGLFARAISESPAAGMVRSREVAAEFAARFANLIGARTQDAANA
Rv2045c|M.tuberculosis_H37Rv        LAVPAAKGLFARAISESPAAGMVRSREVAAEFAARFANLIGARTQDAANA
MAV_2466|M.avium_104                LAVPAAKGLFAQAISESPASGLVRSQEVAAEFANRFANLLGVRRQDAANA
MUL_2261|M.ulcerans_Agy99           LAVPAAKGLFARAISESPAAGMVRPREIAAEFATRFARLLGARKHDAASA
TH_2744|M.thermoresistible__bu      LASPAARGLFHRAIAQSPALPLIADADLRAGRAARFVERLGV-----GVD
MSMEG_3002|M.smegmatis_MC2_155      LASPSAEGLFARAIAQSPALPLIADRDVRARQAHRFLEIVGE-----DPA
Mflv_3787|M.gilvum_PYR-GCK          MAAPSATGLFGRAIAQSPALPLIADRHLRAANAQEFLRRLGV-----DAA
Mvan_2609|M.vanbaalenii_PYR-1       MAAPSAQRLFHRAIAQSPALPLVADREYRAANAHEFLRRLGV-----GAG
MAB_2866c|M.abscessus_ATCC_199      LASPAAEGLFGRAIAQSPALPLIADKALRDKRAHRYLELLDVT----DPS
MMAR_4363|M.marinum_M               LVTPAARGLFSRAIAQSSPATSVYDRERAQRVAVHLLDKLGVAAS--DVD
                                    :. *:*  ** :**::*..   :         * .    :.         

Mb2071c|M.bovis_AF2122/97           LMQASPAQLVEAQHHLIRQGMRKRLG-AFPIGPVFGDDYLPMDPVEAMRS
Rv2045c|M.tuberculosis_H37Rv        LMQASPAQLVEAQHHLIRQGMRKRLG-AFPIGPVFGDDYLPMDPVEAMRS
MAV_2466|M.avium_104                LMQASAAQLVKTQHRLIDEGMQDRLG-AFPIGPVVGDDILPTDPVEAMRR
MUL_2261|M.ulcerans_Agy99           LMRATAAQLVQTQHRLIDQGMQKRLG-AFPIGPTFGDDCLPLDPVEAMRA
TH_2744|M.thermoresistible__bu      DIRELPQRALRRAAGLVQLDSIADSP-ALAYGLTHGVDLLPRHPIAAARA
MSMEG_3002|M.smegmatis_MC2_155      KLRDLPQKQLRRAAGQVQLESAQHTP-TLAYGLTHGVDLLPRHPIDAARA
Mflv_3787|M.gilvum_PYR-GCK          EVKTLPQRQLRRAAGLVQLTSAATTP-TLAYGLTTGTDLLPLHPLDAARQ
Mvan_2609|M.vanbaalenii_PYR-1       EVKALPQRQLRRAAGILQLKSAANTP-TLAYGLTYGTELLPQHPVAAARE
MAB_2866c|M.abscessus_ATCC_199      RLKVLPQRELRRGAAKLQIESATETP-VLGYGLAHGTELLPYHPIEAARR
MMAR_4363|M.marinum_M               KLTQLPTAAIVAASTEVFNEVPVRNPGTLAFVPIVDGDVLTDYPVKVAQE
                                     :   .   :      :          .:      . : *.  *: . : 

Mb2071c|M.bovis_AF2122/97           GRVHAVPLIVGTNAEEGRLFTR-FLGMLPTNEPMVEELLSGMKPAD----
Rv2045c|M.tuberculosis_H37Rv        GRVHAVPLIVGTNAEEGRLFTR-FLGMLPTNEPMVEELLSGMKPAD----
MAV_2466|M.avium_104                GEAHRVPLIVGTNAEEGRLFTR-FLAMLPTNESMVEELLADAEPAV----
MUL_2261|M.ulcerans_Agy99           GQSHKVPLIVGTNADEGRLFTR-FLKMLPTNKAMIDELLADTEPAT----
TH_2744|M.thermoresistible__bu      GTVHPVPLIIGTNSDEASMFAWGRPPMLPTTPDRVEHYFRRHAPHA----
MSMEG_3002|M.smegmatis_MC2_155      GEVLPVPLIIGTNSHEASMFAWGKPPMLPTTVAGVEHYFRRKHAGA----
Mflv_3787|M.gilvum_PYR-GCK          GRMSSVPLIVGTNSHEASMFAWTKPPMLPTTRESIDGFFERTAPHA----
Mvan_2609|M.vanbaalenii_PYR-1       GRTSGVPLIIGTNSHEASMFAWTKPPMLPTTKASIDGYFQRVAPDA----
MAB_2866c|M.abscessus_ATCC_199      GEVHQVPLIIGSNSHEASMFARVKPPMLPTTEPTVNGYFNRIGPEY----
MMAR_4363|M.marinum_M               GRSHPVPLLIGTNKHEAALFRLMRSPLMPITPRAITSMFTQIAAEQPDLQ
                                    *    ***::*:* .*. :*      ::* .   :   :    .      

Mb2071c|M.bovis_AF2122/97           ---RERITAAYPNYPAPSACIQLGGDFAFSSAAWQIAEAHGANAPTYLYR
Rv2045c|M.tuberculosis_H37Rv        ---RERITAAYPNYPAPSACIQLGGDFAFSSAAWQIAEAHGANAPTYLYR
MAV_2466|M.avium_104                ---RERITAAYPDYPDRSACIQLGGDFAFGSAAWQIAEAHCAHAPTYLYR
MUL_2261|M.ulcerans_Agy99           ---RERITAAYPNYPESAACIQLGGDFAFNAAAWQIAEAQGVHAPTYLYR
TH_2744|M.thermoresistible__bu      ---RDTVLAAYPGYPRRRAAVAVGADVMFAAPTWAFADAYSAHAPTYLYR
MSMEG_3002|M.smegmatis_MC2_155      ---KDRILSAYPAFPRRRALVAFGSDVMFGAPTWAFSDAYSAHAPTHVYR
Mflv_3787|M.gilvum_PYR-GCK          ---KRQVLQAYPGYPRRSALVAIGADAMFGGPTWAFADAYSAHAPTRMYR
Mvan_2609|M.vanbaalenii_PYR-1       ---KQRVLQAYPGYPRRSALVALGSDAMFGGPTWAFADAYSALAPTRMYR
MAB_2866c|M.abscessus_ATCC_199      ---QDAIIAAYPGYPSRQALVAVGSDAMFAAPMWAFADAYSAFVDTYMYR
MMAR_4363|M.marinum_M               LPTEEEIGLAYSRLRRRARPLSIATDVGFRMPSVWLAEGHSRVAPVYLYR
                                       .  :  **.        : .. *  *  .   :::.    . . :**

Mb2071c|M.bovis_AF2122/97           YDYAPRTLRWSGFGATHATELFAVFDIYRTRFGALLTAAADRRAALRVSN
Rv2045c|M.tuberculosis_H37Rv        YDYAPRTLRWSGFGATHATELFAVFDIYRTRFGALLTAAADRRAALRVSN
MAV_2466|M.avium_104                YDYAPRTLRWSGFGATHATELLAVFDVYRTRFGALLTAAADRRAALRVSN
MUL_2261|M.ulcerans_Agy99           YDYAPRTLRWSGFGATHATELFAVFDIYRTRFGALLTAAADRRHALRVSD
TH_2744|M.thermoresistible__bu      FEHAPPALRALGLGATHGSEIVHIQHTYASYPGRRLHPLG-ARRTPAVGR
MSMEG_3002|M.smegmatis_MC2_155      FDHTTWTLRALGLGATHGSEIVHIQHSYGSYLGRRLHPLG-RHVQPSVGR
Mflv_3787|M.gilvum_PYR-GCK          FDHFGMSLRMLGLGATHGSEIVHIHHSYASFVGRKLHPLG-RRIQPGVGR
Mvan_2609|M.vanbaalenii_PYR-1       FDHFGWSLRMLGLGATHGSEIVHIHHSYESFVGRKLHPLG-RRIQPGVGR
MAB_2866c|M.abscessus_ATCC_199      FDHTAWGLKLLGLGATHGSEIVHVQHSYGSFVGMLLSPLG-ARMMPSVGR
MMAR_4363|M.marinum_M               FDYSTPLLKLLLVRAAHATELPYVWGNLGGPQDPTLRLGG-AKTAKAVSK
                                    :::    *:   . *:*.:*:  :        .  *   .  :    *. 

Mb2071c|M.bovis_AF2122/97           EVQRRWRCFSQ-----IGVPGDDWPAYTQDDR-AVLVFDRRCRIEFDPHQ
Rv2045c|M.tuberculosis_H37Rv        EVQRRWRCFSQ-----IGVPGDDWPAYTQDDR-AVLVFDRRCRIEFDPHQ
MAV_2466|M.avium_104                QVQRRWRAFSR-----TGVPGEDWPRYTAADR-AVLVFDRKSRVEFDPHP
MUL_2261|M.ulcerans_Agy99           EVIRRWRSFSQ-----TGTPGEDWPAYTHTRR-AVMVIDRKSRVEIDPHR
TH_2744|M.thermoresistible__bu      RMQRAWLAFAT-----DDHPGSDWPRYDTGRRRTRLIRTGEDLVADDPDV
MSMEG_3002|M.smegmatis_MC2_155      RMQRTWLDFAR-----AEIA--DWPFYDTERRLTRVIRSTRDDTVADPDA
Mflv_3787|M.gilvum_PYR-GCK          RMQRSWLDFARDN---AEVDEGHWPLYEIGARLTRLITSTRDVMASDPDR
Mvan_2609|M.vanbaalenii_PYR-1       RMQRAWLDFARGS---EDVDDEHWPLYETGERLTRLIASTRDVMASDPDR
MAB_2866c|M.abscessus_ATCC_199      RMQRAWLDFAT------GAGPEDWPTYGADGRRTRIIRSRSDVTVEDPDS
MMAR_4363|M.marinum_M               RMRTRWINFATQDNPAGPAGEPDWPAYQDGDR-ACLVIDKSDRVARDIDA
                                    .:   *  *:            .** *    * : ::         * . 

Mb2071c|M.bovis_AF2122/97           HRRIAWDGFSLAN-----
Rv2045c|M.tuberculosis_H37Rv        HRRIAWDGFSLAN-----
MAV_2466|M.avium_104                HRRMAWDGFSLAR-----
MUL_2261|M.ulcerans_Agy99           HRRLAWDGFSLAR-----
TH_2744|M.thermoresistible__bu      VRRTAWQGVY--------
MSMEG_3002|M.smegmatis_MC2_155      LRRAVWEGLY--------
Mflv_3787|M.gilvum_PYR-GCK          DRREAWAQVYQPPKRSSV
Mvan_2609|M.vanbaalenii_PYR-1       DRRQAWAAVY--------
MAB_2866c|M.abscessus_ATCC_199      VRRIAWAQVH--------
MMAR_4363|M.marinum_M               PIRAAWGREVVGFR----
                                      * .*