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AKKPIRINTVNGTVEGFTRGGVHRFRGIPYAEPPVGPLRLRAPRPALPWTGVRTCRAWGAASIQQHRYAI ILPGKPQKLSEDCLTLNVVAPEGPVSGPLPVMFFIHGGGYFLGSSATPLYDGASLARRGCVYVSVNYRLG GLGCVDLSSLSDDKHTIDSNLYLRDLVLALQWVHDNIGAFGGDPNNVTIFGESAGSHAVNTLLAVPSAAG LFHRAICQSTASGLVVSAEDAAVNARQFAKYLGASDSNAAATVLAAKPKDLVKALFRLIGSAKHVPGLSL RIGPSIDGDVLPQDPIEAMERGESHRVPLIIGYNAEEATLFTKVLKILPITPEALEHSLSKGGPDFVRRI IEGYDGYPSQQALLQLAGDLAFGSAAWRVAEAHGRYAPTYFYRYDYTTRALRRYGLGPTHAIELLAVFGT YRTVAGPFLAGRADRAVARSVSDEMQRRWLAFAHTGVPGDGWPAHTVPDRQVLIIDNPSRLEADPDADRR PLWQDVTSIV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3452c | - | - | 100% (501) | carboxylesterase LipT |
| M. abscessus ATCC 19977 | MAB_3453c | - | 0.0 | 63.14% (491) | carboxylesterase LipT |
| M. abscessus ATCC 19977 | MAB_1223 | - | e-164 | 56.85% (496) | carboxylesterase (LipT) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2071c | lipT | 1e-158 | 57.69% (494) | carboxylesterase LipT |
| M. gilvum PYR-GCK | Mflv_3125 | - | 1e-162 | 55.71% (499) | carboxylesterase, type B |
| M. tuberculosis H37Rv | Rv2045c | lipT | 1e-158 | 57.69% (494) | carboxylesterase LipT |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_3020 | lipT | 1e-158 | 56.88% (494) | carboxylesterase, LipT |
| M. avium 104 | MAV_2466 | - | 1e-163 | 58.63% (498) | LppT protein |
| M. smegmatis MC2 155 | MSMEG_3848 | - | 1e-163 | 58.27% (496) | para-nitrobenzyl esterase |
| M. thermoresistible (build 8) | TH_0737 | lipT | 1e-166 | 59.52% (499) | Probable carboxylesterase LipT |
| M. ulcerans Agy99 | MUL_2261 | lipT | 1e-157 | 56.68% (494) | carboxylesterase, LipT |
| M. vanbaalenii PYR-1 | Mvan_3408 | - | 1e-156 | 55.82% (498) | carboxylesterase, type B |
CLUSTAL 2.0.9 multiple sequence alignment
TH_0737|M.thermoresistible__bu -------------VMHEHRVRVQISTGTIEGFTRDGVHRWRAIPYAKPPV
Mvan_3408|M.vanbaalenii_PYR-1 --------------MHEHTVRVRTASGTVEGFTRDGVHRWRSIPYARPPV
MSMEG_3848|M.smegmatis_MC2_155 --------------MHERTVRAEISTGIIEGFTRDGVHRWRSIPYARAPI
Mflv_3125|M.gilvum_PYR-GCK MVRQAGREFDTVGRMHEHTVRVKIASGTVEGFTRDGVHRWRSIPYARPPV
Mb2071c|M.bovis_AF2122/97 ----MALESATVGSMHERTVRARTATGIVEGFTRDGVHRWRSIPYARAPV
Rv2045c|M.tuberculosis_H37Rv ----MALESATVGSMHERTVRARTATGIVEGFTRDGVHRWRSIPYARAPV
MMAR_3020|M.marinum_M --------------MHERTVRARTATGIVEGFTRDGVHRWRSIPYARAPI
MUL_2261|M.ulcerans_Agy99 --------------MHERTVRARTATGVVEGFTRDGVHRWRSIPYARAPI
MAV_2466|M.avium_104 --------------MHDRTVRARTATGIVEGFTRDGVHRWRSIPYARPPV
MAB_3452c|M.abscessus_ATCC_199 --------------MAKKPIRINTVNGTVEGFTRGGVHRFRGIPYAEPPV
* .: :* . .* :*****.****:*.****..*:
TH_0737|M.thermoresistible__bu GPLRLRAPEPADPWPGVRHCHGFGNCAPQERKYTLIGLG----KYQPMGE
Mvan_3408|M.vanbaalenii_PYR-1 GRLRYRAPEPVQPWSGVRHCHGFLSCAPQHRRYTLIGVR----KYQPTSE
MSMEG_3848|M.smegmatis_MC2_155 GPLRLRAPQPAEPWPGVRYCHGFGFCAPQQRRYTLLGVG----KYQPTSE
Mflv_3125|M.gilvum_PYR-GCK GPLRYRAPRPVQPWPGVRYCHGFGACAPQQRMYTLLAPG----RYQPMSE
Mb2071c|M.bovis_AF2122/97 GSLRFRAPQPAQPWPGVRHCHTFANCAPQQRRYTVMGIG----RYQTRSE
Rv2045c|M.tuberculosis_H37Rv GSLRFRAPQPAQPWPGVRHCHTFANCAPQQRRYTVMGIG----RYQTRSE
MMAR_3020|M.marinum_M GPLRFRAPRPPQPWSGVRHCHGFTHCSPQQRRYTMLGLG----KYQPMSE
MUL_2261|M.ulcerans_Agy99 GLLRFRAPRPPQPWSGVRHCHGFTHCSPQQRRYTMLGLG----KYQPMSE
MAV_2466|M.avium_104 GDLRFRAPQPAQPWSGVRHCHGFANCAPQQRRYTLLGLSGLGGRYQPMSE
MAB_3452c|M.abscessus_ATCC_199 GPLRLRAPRPALPWTGVRTCRAWGAASIQQHRYAIILPG----KPQKLSE
* ** ***.* **.*** *: : .: *.: *::: : * .*
TH_0737|M.thermoresistible__bu DCLTLNVVAPE--HPPDS--PMPVLVFIHGGGYLLGSSATPIYDGAALAR
Mvan_3408|M.vanbaalenii_PYR-1 DCLTLNVVAPE--GAASAGEPLPVMFFIHGGGYILGSSATPLYDGAALAR
MSMEG_3848|M.smegmatis_MC2_155 DCLTLNVVAPE--KPHDG--PLPVMFFVHGGGYVLGSSATPIYDGAALAR
Mflv_3125|M.gilvum_PYR-GCK DCLTLNVVAPADAEARAADGPLPVMVFIHGGGYLLGSSATPVYDGASLAR
Mb2071c|M.bovis_AF2122/97 DCLTLNVVTPE----EPATQPLPVMVFIHGGGYILGSSATPIYDGAALAR
Rv2045c|M.tuberculosis_H37Rv DCLTLNVVTPE----EPATQPLPVMVFIHGGGYILGSSATPIYDGAALAR
MMAR_3020|M.marinum_M DCLTLNVVAPE----APSHRPLPVMVFIHGGGYILGSSATPIYDGAALAR
MUL_2261|M.ulcerans_Agy99 DCLTLNVVAPE----APTHRPLPVMVFIHGGGYILGSSATPIYDGAALAR
MAV_2466|M.avium_104 DCLTLNVVTPE----APAEGPLPVMVFIHGGGYFLGSSATPLYDGAALAR
MAB_3452c|M.abscessus_ATCC_199 DCLTLNVVAPE----GPVSGPLPVMFFIHGGGYFLGSSATPLYDGASLAR
********:* *:**:.*:*****.*******:****:***
TH_0737|M.thermoresistible__bu RGCVYVSVNYRLGALGCMDLSSLSTRRHPIDSNLFLRDLVLALQWVRDNI
Mvan_3408|M.vanbaalenii_PYR-1 RGCVYVSVNYRLGPLGCMDLSSLSTPENPIDDNLFLRDLVMALRWVRDNV
MSMEG_3848|M.smegmatis_MC2_155 RGCVYVSVNYRLGVLGAMELSSLSTPEHPIDDNLFLRDLVLALQWVRDNI
Mflv_3125|M.gilvum_PYR-GCK KGCVYISVNYRLGALGCLELSSLSTPEAPIDDNLFLRDLVMALRWVRDNV
Mb2071c|M.bovis_AF2122/97 RGCVYVSVNYRLGALGCLDLSSLSTPQITLDSNVYLRDLVLALRWVHDNI
Rv2045c|M.tuberculosis_H37Rv RGCVYVSVNYRLGALGCLDLSSLSTPQITLDSNVYLRDLVLALRWVHDNI
MMAR_3020|M.marinum_M RGCVYVSVNYRLGALGCLDLSSLSTPDIAIDGNLYLRDLVMALQWIQDNI
MUL_2261|M.ulcerans_Agy99 RGCVYVSVNYRLGALGCLDLSSLSTPDIAIDGNLYLRDLVMALQWIQDNI
MAV_2466|M.avium_104 RGCVYVSVNYRLGALGCVDFSSLSTPEIPLESNLYLRDLVLALQWVRDNI
MAB_3452c|M.abscessus_ATCC_199 RGCVYVSVNYRLGGLGCVDLSSLSDDKHTIDSNLYLRDLVLALQWVHDNI
:****:******* **.:::**** .::.*::*****:**:*::**:
TH_0737|M.thermoresistible__bu SVFGGDPGNVTIFGESAGAHAVATLMAVPAAKGLFSQAISQSPASGMVRS
Mvan_3408|M.vanbaalenii_PYR-1 AAFGGDPDKVTIFGESAGAHAVATLLATPQAKGLFAQAISESPASGMVRS
MSMEG_3848|M.smegmatis_MC2_155 AVFGGDPDNVTIFGESAGAHAVATLLAVPAARGLFARVISESPASGMVSS
Mflv_3125|M.gilvum_PYR-GCK AAFGGDPGNVTIFGESAGAHAVSTLVATPEAEGLFAQAIAQSPASGMISD
Mb2071c|M.bovis_AF2122/97 AEFGGDPGNVTIFGESAGAHITATLLAVPAAKGLFARAISESPAAGMVRS
Rv2045c|M.tuberculosis_H37Rv AEFGGDPGNVTIFGESAGAHITATLLAVPAAKGLFARAISESPAAGMVRS
MMAR_3020|M.marinum_M AEFGGDPDNVTIFGESAGAHITATLLAVPAAKGLFARAISESPAAGMVRP
MUL_2261|M.ulcerans_Agy99 AEFGGDPDNVTIFGESAGAHITATLLAVPAAKGLFARAISESPAAGMVRP
MAV_2466|M.avium_104 AEFGGDPDNVTIFGESAGACITATLLAVPAAKGLFAQAISESPASGLVRS
MAB_3452c|M.abscessus_ATCC_199 GAFGGDPNNVTIFGESAGSHAVNTLLAVPSAAGLFHRAICQSTASGLVVS
. *****.:*********: . **:*.* * *** :.*.:*.*:*::
TH_0737|M.thermoresistible__bu ADVAAEFARRFADLLG-AGRDPAAALMAASPADLVRALDELISRGMTDMP
Mvan_3408|M.vanbaalenii_PYR-1 TEMAAKFASRFADLVANDGGDAAAALMSASPHALIAALDDLVANGFKDMP
MSMEG_3848|M.smegmatis_MC2_155 ADTAARLAGQYAGIIGHGGRDAAEALKTLSPAQLGRALEELINRGMTDMP
Mflv_3125|M.gilvum_PYR-GCK ADIAADYAQRFARQLGADGKDGARALLAARPADLVDALERLIVEGQRDLV
Mb2071c|M.bovis_AF2122/97 REVAAEFAARFANLIGARTQDAANALMQASPAQLVEAQHHLIRQGMRKRL
Rv2045c|M.tuberculosis_H37Rv REVAAEFAARFANLIGARTQDAANALMQASPAQLVEAQHHLIRQGMRKRL
MMAR_3020|M.marinum_M REIAAEFATRFARLLGARKHDAASALMRATAAQLVQTQHRLIDQGMQKRL
MUL_2261|M.ulcerans_Agy99 REIAAEFATRFARLLGARKHDAASALMRATAAQLVQTQHRLIDQGMQKRL
MAV_2466|M.avium_104 QEVAAEFANRFANLLGVRRQDAANALMQASAAQLVKTQHRLIDEGMQDRL
MAB_3452c|M.abscessus_ATCC_199 AEDAAVNARQFAKYLGASDSNAAATVLAAKPKDLVKALFRLIGSAKHVPG
: ** * ::* :. : * :: . * : *: .
TH_0737|M.thermoresistible__bu GAFAVGPSYGDDCLPRHPVEAMRDGRAHDVPLIVGTNAEEGRLFRRFLPL
Mvan_3408|M.vanbaalenii_PYR-1 GAFPVGPTYGTEYLPKDPVEAMRDGTAHRVPLIVGTNAEEGRLFTRFLPL
MSMEG_3848|M.smegmatis_MC2_155 GAFPVGPTYGTEFLPTDPVEAMAAGSAHRVPLIVGNNAEEGRLFTRFLPL
Mflv_3125|M.gilvum_PYR-GCK GAFAIGPTYGTEYLPEDPVEAMRSGRAHPVPLIVGTNADEGRLFTRFLKL
Mb2071c|M.bovis_AF2122/97 GAFPIGPVFGDDYLPMDPVEAMRSGRVHAVPLIVGTNAEEGRLFTRFLGM
Rv2045c|M.tuberculosis_H37Rv GAFPIGPVFGDDYLPMDPVEAMRSGRVHAVPLIVGTNAEEGRLFTRFLGM
MMAR_3020|M.marinum_M GAFPIGPTFGDDCLPLDPVEAMRAGQSHKVPLIVGTNADEGRLFTRFLKM
MUL_2261|M.ulcerans_Agy99 GAFPIGPTFGDDCLPLDPVEAMRAGQSHKVPLIVGTNADEGRLFTRFLKM
MAV_2466|M.avium_104 GAFPIGPVVGDDILPTDPVEAMRRGEAHRVPLIVGTNAEEGRLFTRFLAM
MAB_3452c|M.abscessus_ATCC_199 LSLRIGPSIDGDVLPQDPIEAMERGESHRVPLIIGYNAEEATLFTKVLKI
:: :** . : ** .*:*** * * ****:* **:*. ** :.* :
TH_0737|M.thermoresistible__bu LPISEPMIEALFGDTDAEVRDRIIAAYPGYPDADACIRLGGDFAFGTAAW
Mvan_3408|M.vanbaalenii_PYR-1 LPTTEQTIEIMLGDTDAEVRNRIMSAYPDYPKPDACVQIGGDFTFSTAAW
MSMEG_3848|M.smegmatis_MC2_155 LPTNEPMIEKLFADADPEHRERILSAYPGYPDRDVCVRLGGDFAFGSATW
Mflv_3125|M.gilvum_PYR-GCK LPTNEQAIEQLLSAVEPEARQRVLAAYPKYPAVDACVAFGGDFIFGSAVW
Mb2071c|M.bovis_AF2122/97 LPTNEPMVEELLSGMKPADRERITAAYPNYPAPSACIQLGGDFAFSSAAW
Rv2045c|M.tuberculosis_H37Rv LPTNEPMVEELLSGMKPADRERITAAYPNYPAPSACIQLGGDFAFSSAAW
MMAR_3020|M.marinum_M LPTNKAMIDELLADTEPATRERITAAYPNYPESAACIQLGGDFAFNAAAW
MUL_2261|M.ulcerans_Agy99 LPTNKAMIDELLADTEPATRERITAAYPNYPESAACIQLGGDFAFNAAAW
MAV_2466|M.avium_104 LPTNESMVEELLADAEPAVRERITAAYPDYPDRSACIQLGGDFAFGSAAW
MAB_3452c|M.abscessus_ATCC_199 LPITPEALEHSLSKGGPDFVRRIIEGYDGYPSQQALLQLAGDLAFGSAAW
** . :: :. . *: .* ** . : :.**: *.:*.*
TH_0737|M.thermoresistible__bu EISEAHSRHAPTYVYRYDYAPRMLHWSGIGATHATELLAVFGTYRTRPGR
Mvan_3408|M.vanbaalenii_PYR-1 QIGEAHSRHAPTFVYRYDYAPRPLHWSGMGATHATELLAVFDIYRTMPGA
MSMEG_3848|M.smegmatis_MC2_155 QVAEAHSRHAPTYVYRYDYAPRALRWSGLGATHAMELLAVFDTYRTRYGS
Mflv_3125|M.gilvum_PYR-GCK QIAHAHSAFAPTYVYRYDYATAALRLSGMGATHATELLAVFDVYRSRFGK
Mb2071c|M.bovis_AF2122/97 QIAEAHGANAPTYLYRYDYAPRTLRWSGFGATHATELFAVFDIYRTRFGA
Rv2045c|M.tuberculosis_H37Rv QIAEAHGANAPTYLYRYDYAPRTLRWSGFGATHATELFAVFDIYRTRFGA
MMAR_3020|M.marinum_M QIAEAQGAHAPTYLYRYDYAPRTLRWSGFGATHATELFAVFDIYRTRFGA
MUL_2261|M.ulcerans_Agy99 QIAEAQGVHAPTYLYRYDYAPRTLRWSGFGATHATELFAVFDIYRTRFGA
MAV_2466|M.avium_104 QIAEAHCAHAPTYLYRYDYAPRTLRWSGFGATHATELLAVFDVYRTRFGA
MAB_3452c|M.abscessus_ATCC_199 RVAEAHGRYAPTYFYRYDYTTRALRRYGLGPTHAIELLAVFGTYRTVAGP
.:..*: ***:.*****:. *: *:*.*** **:***. **: *
TH_0737|M.thermoresistible__bu LLTLAGDWVSAQRVSSDLQRRWLAFGRTGVPGDDWPAYTAEHRPVRVFDR
Mvan_3408|M.vanbaalenii_PYR-1 LLTLAGDWRSARRVSKDVQRRWSSFSRTGVPGADWPRYSAEDRPVMVFDR
MSMEG_3848|M.smegmatis_MC2_155 MLTAMADRRSARRVSRDIQTRWRDFSRAGVPGDGWPAYRHDERAVYVFDT
Mflv_3125|M.gilvum_PYR-GCK LLAAGLDSRSAKKVTDDVQKRWLGFAERAVPGGDWPQYTRDERAVLVLDR
Mb2071c|M.bovis_AF2122/97 LLTAAADRRAALRVSNEVQRRWRCFSQIGVPGDDWPAYTQDDRAVLVFDR
Rv2045c|M.tuberculosis_H37Rv LLTAAADRRAALRVSNEVQRRWRCFSQIGVPGDDWPAYTQDDRAVLVFDR
MMAR_3020|M.marinum_M LLTAAADRRHALRVSDEVIRRWRSFSQTGTPGEDWPAYTHTRRAVMVIDR
MUL_2261|M.ulcerans_Agy99 LLTAAADRRHALRVSDEVIRRWRSFSQTGTPGEDWPAYTHTRRAVMVIDR
MAV_2466|M.avium_104 LLTAAADRRAALRVSNQVQRRWRAFSRTGVPGEDWPRYTAADRAVLVFDR
MAB_3452c|M.abscessus_ATCC_199 FLAGRADRAVARSVSDEMQRRWLAFAHTGVPGDGWPAHTVPDRQVLIIDN
:*: * * *: :: ** *.. ..** .** : * * ::*
TH_0737|M.thermoresistible__bu NPRVEYDPDAHRRQAWQGFTLTRPDRN
Mvan_3408|M.vanbaalenii_PYR-1 HPRLEYDPHAHRRQAWEGFSLA-----
MSMEG_3848|M.smegmatis_MC2_155 RPRVEYDPDADRRLAWEGFSLAQR---
Mflv_3125|M.gilvum_PYR-GCK RRRVEFDPHSERRQAWEGFFLATR---
Mb2071c|M.bovis_AF2122/97 RCRIEFDPHQHRRIAWDGFSLAN----
Rv2045c|M.tuberculosis_H37Rv RCRIEFDPHQHRRIAWDGFSLAN----
MMAR_3020|M.marinum_M KSRVEIDPHQHRRLAWDGFSLAR----
MUL_2261|M.ulcerans_Agy99 KSRVEIDPHRHRRLAWDGFSLAR----
MAV_2466|M.avium_104 KSRVEFDPHPHRRMAWDGFSLAR----
MAB_3452c|M.abscessus_ATCC_199 PSRLEADPDADRRPLWQDVTSIV----
*:* **. .** *:..